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Transcriptional analysis links B cells and TERT expression to favorable prognosis in head and neck cancer. PNAS Nexus. 2023 Mar; 2(3):pgad046.
Xian S, Dosset M, Castro A, Carter H, Zanetti M. PMID: 36909826; PMCID: PMC10003760.
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PubMed Mentions:
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Subcellular location of source proteins improves prediction of neoantigens for immunotherapy. EMBO J. 2022 12 15; 41(24):e111071.
Castro A, Kaabinejadian S, Yari H, Hildebrand W, Zanetti M, Carter H. PMID: 36314681; PMCID: PMC9753441.
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PubMed Mentions: Fields:
Translation:
Humans
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Structure-selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern. PLoS Pathog. 2022 07; 18(7):e1010686.
Almanza G, Clark AE, Kouznetsova V, Olmedillas E, Castro A, Tsigelny IF, Wu Y, Gao GF, Leibel SL, Bray W, Ollmann Saphire E, Carlin AF, Zanetti M. PMID: 35862442; PMCID: PMC9302722.
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PubMed Mentions: Fields:
Translation:
AnimalsCellsPHPublic Health
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Disulfiram's journey from rubber vulcanization to T-cell activation. EMBO J. 2022 08 16; 41(16):e111862.
Dosset M, Zanetti M. PMID: 35848116; PMCID: PMC9379543.
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PubMed Mentions: Fields:
Translation:
Humans
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The Unfolded Protein Response at the Tumor-Immune Interface. Front Immunol. 2022; 13:823157.
Zanetti M, Xian S, Dosset M, Carter H. PMID: 35237269; PMCID: PMC8882736.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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The unfolded protein response links tumor aneuploidy to local immune dysregulation. EMBO Rep. 2021 12 06; 22(12):e52509.
Xian S, Dosset M, Almanza G, Searles S, Sahani P, Waller TC, Jepsen K, Carter H, Zanetti M. PMID: 34698427; PMCID: PMC8647024.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Neoantigen Controversies. Annu Rev Biomed Data Sci. 2021 07 20; 4:227-253.
Castro A, Zanetti M, Carter H. PMID: 34465181; PMCID: PMC10146390.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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In silico analysis suggests less effective MHC-II presentation of SARS-CoV-2 RBM peptides: Implication for neutralizing antibody responses. PLoS One. 2021; 16(2):e0246731.
Castro A, Ozturk K, Zanetti M, Carter H. PMID: 33571241; PMCID: PMC7877779.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Strength of immune selection in tumors varies with sex and age. Nat Commun. 2020 08 17; 11(1):4128.
Castro A, Pyke RM, Zhang X, Thompson WK, Day CP, Alexandrov LB, Zanetti M, Carter H. PMID: 32807809; PMCID: PMC7431859.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Telomerase and CD4 T Cell Immunity in Cancer. Cancers (Basel). 2020 Jun 25; 12(6).
Dosset M, Castro A, Carter H, Zanetti M. PMID: 32630460; PMCID: PMC7352225.
View in:
PubMed Mentions:
12
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IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival. PLoS Biol. 2020 06; 18(6):e3000687.
Batista A, Rodvold JJ, Xian S, Searles SC, Lew A, Iwawaki T, Almanza G, Waller TC, Lin J, Jepsen K, Carter H, Zanetti M. PMID: 32520957; PMCID: PMC7307794.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells. Sci Rep. 2020 05 20; 10(1):8348.
Rodvold JJ, Xian S, Nussbacher J, Tsui B, Cameron Waller T, Searles SC, Lew A, Jiang P, Babic I, Nomura N, Lin JH, Kesari S, Carter H, Zanetti M. PMID: 32433555; PMCID: PMC7239929.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Ubi Maior Minor Cessat. Crit Rev Immunol. 2020; 40(3):255-262.
Zanetti M. PMID: 33389889.
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PubMed Mentions: Fields:
Translation:
HumansCells
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PERK-mediated induction of microRNA-483 disrupts cellular ATP homeostasis during the unfolded protein response. J Biol Chem. 2020 01 03; 295(1):237-249.
Hiramatsu N, Chiang K, Aivati C, Rodvold JJ, Lee JM, Han J, Chea L, Zanetti M, Koo EH, Lin JH. PMID: 31792031; PMCID: PMC6952592.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes. BMC Med Genomics. 2019 07 25; 12(Suppl 6):107.
Castro A, Ozturk K, Pyke RM, Xian S, Zanetti M, Carter H. PMID: 31345234; PMCID: PMC6657029.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Extracellular vesicles produced in B cells deliver tumor suppressor miR-335 to breast cancer cells disrupting oncogenic programming in vitro and in vivo. Sci Rep. 2018 12 04; 8(1):17581.
Almanza G, Rodvold JJ, Tsui B, Jepsen K, Carter H, Zanetti M. PMID: 30514916; PMCID: PMC6279829.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Evolutionary Pressure against MHC Class II Binding Cancer Mutations. Cell. 2018 10 04; 175(2):416-428.e13.
Marty Pyke R, Thompson WK, Salem RM, Font-Burgada J, Zanetti M, Carter H. PMID: 30245014; PMCID: PMC6482006.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Insidious communication amongst cancer cells. Mol Cell Oncol. 2018; 5(3):e1356898.
Rodvold JJ, Zanetti M. PMID: 30250884; PMCID: PMC6149878.
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PubMed Mentions:
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Cripto stabilizes GRP78 on the cell membrane. Protein Sci. 2018 03; 27(3):653-661.
Kouznetsova VL, Hu H, Teigen K, Zanetti M, Tsigelny IF. PMID: 29226519; PMCID: PMC5818753.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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A community affair in the tumor microenvironment. Oncotarget. 2017 Dec 05; 8(63):106173-106174.
Rodvold JJ, Kesari S, Zanetti M. PMID: 29290938; PMCID: PMC5739723.
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PubMed Mentions:
1 Fields:
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Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells. Sci Signal. 2017 Jun 06; 10(482).
Rodvold JJ, Chiu KT, Hiramatsu N, Nussbacher JK, Galimberti V, Mahadevan NR, Willert K, Lin JH, Zanetti M. PMID: 28588081; PMCID: PMC5962022.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Chromosomal chaos silences immune surveillance. Science. 2017 01 20; 355(6322):249-250.
Zanetti M. PMID: 28104855.
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PubMed Mentions:
9 Fields:
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Tumor microenvironment on the move and the Aselli connection. Sci Signal. 2016 06 28; 9(434):fs13.
Rodvold JJ, Zanetti M. PMID: 27353363.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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A second chance for telomerase reverse transcriptase in anticancer immunotherapy. Nat Rev Clin Oncol. 2017 02; 14(2):115-128.
Zanetti M. PMID: 27245281.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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High-efficiency Generation of Multiple Short Noncoding RNA in B-cells and B-cell-derived Extracellular Vesicles. Mol Ther Nucleic Acids. 2015 Dec 15; 4:e271.
Almanza G, Zanetti M. PMID: 26670278; PMCID: PMC5014536.
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PubMed Mentions:
2
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Immune modulation by ER stress and inflammation in the tumor microenvironment. Cancer Lett. 2016 09 28; 380(1):227-36.
Rodvold JJ, Mahadevan NR, Zanetti M. PMID: 26525580.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Tapping CD4 T cells for cancer immunotherapy: the choice of personalized genomics. J Immunol. 2015 Mar 01; 194(5):2049-56.
Zanetti M. PMID: 25710958.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Synthesis and delivery of short, noncoding RNA by B lymphocytes. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20182-7.
Almanza G, Anufreichik V, Rodvold JJ, Chiu KT, DeLaney A, Akers JC, Chen CC, Zanetti M. PMID: 24277816; PMCID: PMC3864290.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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A Janus-faced role of the unfolded protein response in antitumor immunity. Oncoimmunology. 2013 May 01; 2(5):e23901.
Mahadevan NR, Rodvold JJ, Zanetti M. PMID: 23762789; PMCID: PMC3667895.
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PubMed Mentions:
3 Fields:
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Cell-extrinsic effects of the tumor unfolded protein response on myeloid cells and T cells. Ann N Y Acad Sci. 2013 May; 1284:6-11.
Zanetti M. PMID: 23651187.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Sensing hyperploidy and immune surveillance: a pas-de-deux. Cell Cycle. 2013 Feb 15; 12(4):544-5.
Mahadevan NR, Zanetti M. PMID: 23370385; PMCID: PMC3594253.
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PubMed Mentions: Fields:
Translation:
Animals
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Cell-extrinsic effects of tumor ER stress imprint myeloid dendritic cells and impair CD8⁺ T cell priming. PLoS One. 2012; 7(12):e51845.
Mahadevan NR, Anufreichik V, Rodvold JJ, Chiu KT, Sepulveda H, Zanetti M. PMID: 23272178; PMCID: PMC3525659.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway. Cancer Lett. 2013 Feb 28; 329(2):236-42.
Kumandan S, Mahadevan NR, Chiu K, DeLaney A, Zanetti M. PMID: 23200669; PMCID: PMC4091625.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Cancer. Immune surveillance from chromosomal chaos? Science. 2012 Sep 28; 337(6102):1616-7.
Zanetti M, Mahadevan NR. PMID: 23019639.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Lipocalin 2 in cancer: when good immunity goes bad. Cancer Lett. 2012 Mar 28; 316(2):132-8.
Rodvold JJ, Mahadevan NR, Zanetti M. PMID: 22075378.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimals
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Tumor stress inside out: cell-extrinsic effects of the unfolded protein response in tumor cells modulate the immunological landscape of the tumor microenvironment. J Immunol. 2011 Nov 01; 187(9):4403-9.
Mahadevan NR, Zanetti M. PMID: 22013206.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner. BMC Cancer. 2011 Jun 07; 11:229.
Mahadevan NR, Rodvold J, Almanza G, Pérez AF, Wheeler MC, Zanetti M. PMID: 21649922; PMCID: PMC3146445.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6561-6.
Mahadevan NR, Rodvold J, Sepulveda H, Rossi S, Drew AF, Zanetti M. PMID: 21464300; PMCID: PMC3081038.
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PubMed Mentions:
134 Fields:
Translation:
AnimalsCells
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Endoplasmic reticulum stress drives a regulatory phenotype in human T-cell clones. Cell Immunol. 2010; 266(1):1-6.
Franco A, Almanza G, Burns JC, Wheeler M, Zanetti M. PMID: 20951371.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Prostate cancer cells undergoing ER stress in vitro and in vivo activate transcription of pro-inflammatory cytokines. J Inflamm Res. 2010; 3:99-103.
Mahadevan NR, Fernandez A, Rodvold JJ, Almanza G, Zanetti M. PMID: 22096360; PMCID: PMC3218737.
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PubMed Mentions:
9
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Selected microRNAs define cell fate determination of murine central memory CD8 T cells. PLoS One. 2010 Jun 22; 5(6):e11243.
Almanza G, Fernandez A, Volinia S, Cortez-Gonzalez X, Croce CM, Zanetti M. PMID: 20582165; PMCID: PMC2889817.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Principles of memory CD8 T-cells generation in relation to protective immunity. Adv Exp Med Biol. 2010; 684:108-25.
Zanetti M, Castiglioni P, Ingulli E. PMID: 20795544.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Identification of immunogenic peptides of the self-tumor antigen: our experience with telomerase reverse transcriptase. Methods Mol Biol. 2010; 651:211-25.
Cortez-Gonzalez X, Zanetti M. PMID: 20686968.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Cutting edge: antigen presentation to CD8 T cells after influenza A virus infection. J Immunol. 2009 Jan 01; 182(1):29-33.
Ingulli E, Funatake C, Jacovetty EL, Zanetti M. PMID: 19109130.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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KDEL-retained antigen in B lymphocytes induces a proinflammatory response: a possible role for endoplasmic reticulum stress in adaptive T cell immunity. J Immunol. 2008 Jul 01; 181(1):256-64.
Wheeler MC, Rizzi M, Sasik R, Almanza G, Hardiman G, Zanetti M. PMID: 18566391.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Protection against influenza A virus by memory CD8 T cells requires reactivation by bone marrow-derived dendritic cells. J Immunol. 2008 Apr 01; 180(7):4956-64.
Castiglioni P, Hall de S, Jacovetty EL, Ingulli E, Zanetti M. PMID: 18354221.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Plasmid DNA and IL-4 modulate expression of mHC class I and costimulatory molecules in B lymphocytes. DNA Cell Biol. 2007 Mar; 26(3):148-59.
Frazzi R, Zanetti M. PMID: 17417943.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Telomerase immunity from bench to bedside: round one. J Transl Med. 2007 Feb 26; 5:12.
Cortez-Gonzalez X, Zanetti M. PMID: 17324292; PMCID: PMC1839079.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Immunity and protection, the unfolding of a tale. Immunol Res. 2007; 38(1-3):305-18.
Zanetti M. PMID: 17917038.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Immunogenic HLA-B7-restricted peptides of hTRT. Int Immunol. 2006 Dec; 18(12):1707-18.
Cortez-Gonzalez X, Sidney J, Adotevi O, Sette A, Millard F, Lemonnier F, Langlade-Demoyen P, Zanetti M. PMID: 17077179.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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T cell memory and protective immunity by vaccination: is more better? Trends Immunol. 2006 Nov; 27(11):511-7.
Zanetti M, Franchini G. PMID: 16997631.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Immune-privileged embryonic Swiss mouse STO and STO cell-derived progenitor cells: major histocompatibility complex and cell differentiation antigen expression patterns resemble those of human embryonic stem cell lines. Immunology. 2006 Sep; 119(1):98-115.
Koch KS, Son KH, Maehr R, Pellicciotta I, Ploegh HL, Zanetti M, Sell S, Leffert HL. PMID: 16836618; PMCID: PMC1782333.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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TLR9-independent activation of B lymphocytes by bacterial DNA. DNA Cell Biol. 2006 May; 25(5):253-61.
Cortez-Gonzalez X, Pellicciotta I, Gerloni M, Wheeler MC, Castiglioni P, Lenert P, Zanetti M. PMID: 16716115.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Ex vivo programming of antigen-presenting B lymphocytes: considerations on DNA uptake and cell activation. Int Rev Immunol. 2006 May-Aug; 25(3-4):83-97.
Wheeler M, Cortez-Gonzalez X, Frazzi R, Zanetti M. PMID: 16818366.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The cooperation between two CD4 T cells induces tumor protective immunity in MUC.1 transgenic mice. J Immunol. 2005 Nov 15; 175(10):6551-9.
Gerloni M, Castiglioni P, Zanetti M. PMID: 16272309.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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T for two: when helpers need help. Autoimmun Rev. 2005 Nov; 4(8):571-8.
Zanetti M. PMID: 16214098.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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In utero DNA immunisation. Immunity over tolerance in fetal life. Vaccine. 2005 Jul 21; 23(33):4273-82.
Rizzi M, Gerloni M, Srivastava AS, Wheeler MC, Schuler K, Carrier E, Zanetti M. PMID: 16005117.
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PubMed Mentions: Fields:
Translation:
AnimalsPHPublic Health
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CD8 T cell priming by B lymphocytes is CD4 help dependent. Eur J Immunol. 2005 May; 35(5):1360-70.
Castiglioni P, Gerloni M, Cortez-Gonzalez X, Zanetti M. PMID: 15816014.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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CD4 T cells in tumor immunity. Springer Semin Immunopathol. 2005 Jun; 27(1):37-48.
Gerloni M, Zanetti M. PMID: 15965712.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Telomerase reverse transcriptase as target for anti-tumor T cell responses in humans. Springer Semin Immunopathol. 2005 Jun; 27(1):87-104.
Zanetti M, Hernandez X, Langlade-Demoyen P. PMID: 15711953.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Genetically programmed B lymphocytes are highly efficient in inducing anti-virus protective immunity mediated by central memory CD8 T cells. Vaccine. 2004 Dec 16; 23(5):699-708.
Castiglioni P, Gerloni M, Zanetti M. PMID: 15542193.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Antigenized antibodies expressing Vbeta8.2 TCR peptides immunize against rat experimental allergic encephalomyelitis. J Immune Based Ther Vaccines. 2004 Nov 12; 2(1):9.
Musselli C, Daverio-Zanetti S, Zanetti M. PMID: 15541175; PMCID: PMC539290.
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PubMed Mentions:
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Antigenicity and immunogenicity of peptide analogues of a low affinity peptide of the human telomerase reverse transcriptase tumor antigen. Eur J Immunol. 2004 Aug; 34(8):2331-41.
Hernández J, Schoeder K, Blondelle SE, Pons FG, Lone YC, Simora A, Langlade-Demoyen P, Wilson DB, Zanetti M. PMID: 15259031.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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B lymphocytes as antigen-presenting cell-based genetic vaccines. Immunol Rev. 2004 Jun; 199:264-78.
Zanetti M, Castiglioni P, Rizzi M, Wheeler M, Gerloni M. PMID: 15233740.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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T cell immunity using transgenic B lymphocytes. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3892-7.
Gerloni M, Rizzi M, Castiglioni P, Zanetti M. PMID: 15004284; PMCID: PMC374340.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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The role of relB in regulating the adaptive immune response. Ann N Y Acad Sci. 2003 Apr; 987:249-57.
Zanetti M, Castiglioni P, Schoenberger S, Gerloni M. PMID: 12727647.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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CD4 T cell priming in dendritic cell-deficient mice. Int Immunol. 2003 Jan; 15(1):127-36.
Castiglioni P, Lu C, Lo D, Croft M, Langlade-Demoyen P, Zanetti M, Gerloni M. PMID: 12502733.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12275-80.
Hernandez J, Garcia-Pons F, Lone YC, Firat H, Schmidt JD, Langlade-Demoyen P, Zanetti M. PMID: 12218171; PMCID: PMC129435.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells