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Samira Dahesh

Title(s)SRA 3, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Investigating Azithromycin Activity Against ESBL-Producing Escherichia coli Under Physiologically Relevant Conditions. J Infect Dis. 2025 Sep 17. Jung S, Dahesh S, Bjånes E, Monk J, Chavarria N, Correa S, Hoffman A, Gage H, Nizet V, Kumaraswamy M. PMID: 40974066.
      View in: PubMed   Mentions:    Fields:    
    2. STING-adjuvanted outer membrane vesicle nanoparticle vaccine against Pseudomonas aeruginosa. JCI Insight. 2025 Sep 09; 10(17). Bjånes E, Krishnan N, Koh T, Ngo AT, Cole J, Olson J, Cornax I, Chen CH, Chavarria N, Dahesh S, Hannah SM, Stream A, Zhang JA, Besançon H, Sun D, Yendluri S, Morrill S, Zhou J, Mohapatra A, Fang RH, Nizet V. PMID: 40705476; PMCID: PMC12487677.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Exploration of virulence and immune evasion functions of the candidate vaccine antigen SpyAD in the globally disseminated M1T1 group A Streptococcus strain. mBio. 2025 Jul 09; 16(7):e0068325. Stream A, Dahesh S, Thomas L, Gao NJ, Bjånes E, Kang K, Koh T, Kapoor N, Nizet V. PMID: 40497733; PMCID: PMC12239572.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Colistin exerts potent activity against mcr+ Enterobacteriaceae via synergistic interactions with the host defense. J Clin Invest. 2025 Jun 16; 135(12). Kumaraswamy M, Riestra AM, Flores A, Dahesh S, Askarian F, Uchiyama S, Monk J, Jung S, Bondsäter G, Nilsson V, Chang M, Bulitta JB, Lang Y, Kousha A, Bjånes E, Chavarria N, Clark T, Seo H, Sakoulas G, Nizet V. PMID: 40261712; PMCID: PMC12165787.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Correction to "Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans". ACS Chem Biol. 2024 Dec 20; 19(12):2593. Ngo TE, Ecker A, Ryu B, Guild A, Remmel A, Boudreau PD, Alexander KL, Naman CB, Glukhov E, Avalon NE, Shende VV, Thomas L, Dahesh S, Nizet V, Gerwick L, Gerwick WH. PMID: 39591979; PMCID: PMC11667661.
      View in: PubMed   Mentions:    Fields:    
    6. Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine Streptomycete. J Nat Prod. 2024 Dec 27; 87(12):2768-2778. Sweeney D, Bogdanov A, Chase AB, Castro-Falcón G, Trinidad-Javier A, Dahesh S, Nizet V, Jensen PR. PMID: 39575834; PMCID: PMC11686505.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    7. Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycetef. bioRxiv. 2024 Oct 29. Sweeney D, Bogdanov A, Chase AB, Castro-Falcón G, Trinidad-Javier A, Dahesh S, Nizet V, Jensen PR. PMID: 39554111; PMCID: PMC11565753.
      View in: PubMed   Mentions:
    8. An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies. mBio. 2024 Aug 14; 15(8):e0084024. Bjånes E, Stream A, Janssen AB, Gibson PS, Bravo AM, Dahesh S, Baker JL, Varble A, Nizet V, Veening J-W. PMID: 38953375; PMCID: PMC11323564.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans. ACS Chem Biol. 2024 03 15; 19(3):619-628. Ngo TE, Ecker A, Ryu B, Guild A, Remmel A, Boudreau PD, Alexander KL, Naman CB, Glukhov E, Avalon NE, Shende VV, Thomas L, Dahesh S, Nizet V, Gerwick L, Gerwick WH. PMID: 38330248; PMCID: PMC10949194.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity. bioRxiv. 2023 Mar 21. Kumaraswamy M, Riestra A, Flores A, Uchiyama S, Dahesh S, Bondsäter G, Nilsson V, Chang M, Seo H, Sakoulas G, Nizet V. PMID: 36993410; PMCID: PMC10055327.
      View in: PubMed   Mentions:
    11. Bicarbonate Effects on Antibacterial Immunity and Mucus Glycobiology in the Cystic Fibrosis Lung: A Review With Selected Experimental Observations. Infect Microbes Dis. 2022 Sep; 4(3):103-110. Siew R, Ou TL, Dahesh S, Akong K, Nizet V. PMID: 36793929; PMCID: PMC9928163.
      View in: PubMed   Mentions: 4  
    12. Effect of eliminating hdcA gene of Staphylococcus epidermidis TYH1 on Histamine production. Iran J Microbiol. 2022 Aug; 14(4):529-534. Pashangeh S, Berizi E, Majlesi M, Ghaderi S, Nizet V, Dahesh S. PMID: 36721505; PMCID: PMC9867640.
      View in: PubMed   Mentions: 1  
    13. Inhibition of histamine accumulation by novel histamine-degrading species of Staphylococcus sp. isolated from goats and sheep milk. Food Sci Nutr. 2022 Feb; 10(2):354-362. Pashangeh S, Shekarforoush SS, Aminlari M, Hosseinzadeh S, Nizet V, Dahesh S, Rahmdel S. PMID: 35154673; PMCID: PMC8825735.
      View in: PubMed   Mentions: 3  
    14. Identifying the effect of vancomycin on health care-associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media. Gigascience. 2021 01 09; 10(1). Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Seif Y, Lamsa A, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Pogliano J, Nizet V, Feist AM, Palsson BO. PMID: 33420779; PMCID: PMC7794652.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. Site-Specific Conjugation of Cell Wall Polyrhamnose to Protein SpyAD Envisioning a Safe Universal Group A Streptococcal Vaccine. Infect Microbes Dis. 2021 Jun; 3(2):87-100. Gao NJ, Uchiyama S, Pill L, Dahesh S, Olson J, Bautista L, Maroju S, Berges A, Liu JZ, Zurich RH, van Sorge N, Fairman J, Kapoor N, Nizet V. PMID: 39450141; PMCID: PMC11501091.
      View in: PubMed   Mentions: 8  
    16. Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. mSystems. 2020 Mar 31; 5(2). Salazar MJ, Machado H, Dillon NA, Tsunemoto H, Szubin R, Dahesh S, Pogliano J, Sakoulas G, Palsson BO, Nizet V, Feist AM. PMID: 32234776; PMCID: PMC7112963.
      View in: PubMed   Mentions: 7     Fields:    
    17. Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media. Sci Data. 2019 12 17; 6(1):322. Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Nizet V, Palsson BO, Feist AM, Pogliano J. PMID: 31848353; PMCID: PMC6917727.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    18. Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin. Antimicrob Agents Chemother. 2019 07; 63(7). Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL. PMID: 31235559; PMCID: PMC6591586.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    19. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media. Sci Data. 2019 04 26; 6(1):43. Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, Nizet V, Palsson BO, Feist AM. PMID: 31028276; PMCID: PMC6486602.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    20. Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry. Cell Chem Biol. 2019 05 16; 26(5):724-736.e7. Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS. PMID: 30853419; PMCID: PMC6525064.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    21. Enhanced topical delivery of non-complexed molecular iodine for Methicillin-resistant Staphylococcus aureus decolonization. Int J Pharm. 2019 Jan 10; 554:81-86. Uchiyama S, Dahesh S, Nizet V, Kessler J. PMID: 30395958.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    22. Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance. Sci Rep. 2018 02 02; 8(1):2215. Choe D, Szubin R, Dahesh S, Cho S, Nizet V, Palsson B, Cho BK. PMID: 29396540; PMCID: PMC5797083.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    23. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. J Antibiot (Tokyo). 2018 02; 71(2):333-338. Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. PMID: 29184121; PMCID: PMC5960985.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    24. Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. J Biol Chem. 2016 Jul 01; 291(27):13964-13973. Hollands A, Corriden R, Gysler G, Dahesh S, Olson J, Raza Ali S, Kunkel MT, Lin AE, Forli S, Newton AC, Kumar GB, Nair BG, Perry JJP, Nizet V. PMID: 27226531; PMCID: PMC4933157.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    25. Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation. J Mol Med (Berl). 2016 Feb; 94(2):219-33. Secundino I, Lizcano A, Roupé KM, Wang X, Cole JN, Olson J, Ali SR, Dahesh S, Amayreh LK, Henningham A, Varki A, Nizet V. PMID: 26411873; PMCID: PMC4766071.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    26. Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. Eur J Med Chem. 2015 Jan 27; 90:448-61. Kang S, Watanabe M, Jacobs JC, Yamaguchi M, Dahesh S, Nizet V, Leyh TS, Silverman RB. PMID: 25461893; PMCID: PMC4291291.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    27. Mutual exclusivity of hyaluronan and hyaluronidase in invasive group A Streptococcus. J Biol Chem. 2014 Nov 14; 289(46):32303-32315. Henningham A, Yamaguchi M, Aziz RK, Kuipers K, Buffalo CZ, Dahesh S, Choudhury B, Van Vleet J, Yamaguchi Y, Seymour LM, Ben Zakour NL, He L, Smith HV, Grimwood K, Beatson SA, Ghosh P, Walker MJ, Nizet V, Cole JN. PMID: 25266727; PMCID: PMC4231703.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    28. The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host Microbe. 2014 Jun 11; 15(6):729-740. van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ETM, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L, Gin J, Cunningham M, Merriman JA, Hütter J, Lepenies B, Rooijakkers SHM, Malley R, Walker MJ, Shattil SJ, Schlievert PM, Choudhury B, Nizet V. PMID: 24922575; PMCID: PMC4078075.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    29. Severe soft tissue infection caused by a non-beta-hemolytic Streptococcus pyogenes strain harboring a premature stop mutation in the sagC gene. J Clin Microbiol. 2013 Jun; 51(6):1962-5. Jantsch J, Gerlach RG, Ensser A, Dahesh S, Popp I, Heeg C, Bleiziffer O, Merz T, Schulz T, Horch RE, Bogdan C, Nizet V, van der Linden M. PMID: 23515542; PMCID: PMC3716101.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    30. Study of streptococcal hemoprotein receptor (Shr) in iron acquisition and virulence of M1T1 group A streptococcus. Virulence. 2012 Nov 15; 3(7):566-75. Dahesh S, Nizet V, Cole JN. PMID: 23076332; PMCID: PMC3545933.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    31. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chem Biol. 2012 May 25; 19(5):559-71. van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. PMID: 22633408; PMCID: PMC3361698.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    32. Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile. PLoS One. 2012; 7(4):e35218. Hertzén E, Johansson L, Kansal R, Hecht A, Dahesh S, Janos M, Nizet V, Kotb M, Norrby-Teglund A. PMID: 22511985; PMCID: PMC3325220.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    33. A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection. J Mol Med (Berl). 2012 Sep; 90(9):1079-89. Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. PMID: 22371073; PMCID: PMC3606899.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    34. A residue in helical conformation in the native state adopts a β-strand conformation in the folding transition state despite its high and canonical Φ-value. Proteins. 2012 May; 80(5):1343-9. Zarrine-Afsar A, Dahesh S, Davidson AR. PMID: 22274997.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    35. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat Immunol. 2011 Sep 04; 12(10):966-74. Kinjo Y, Illarionov P, Vela JL, Pei B, Girardi E, Li X, Li Y, Imamura M, Kaneko Y, Okawara A, Miyazaki Y, Gómez-Velasco A, Rogers P, Dahesh S, Uchiyama S, Khurana A, Kawahara K, Yesilkaya H, Andrew PW, Wong CH, Kawakami K, Nizet V, Besra GS, Tsuji M, Zajonc DM, Kronenberg M. PMID: 21892173; PMCID: PMC3178673.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    36. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. PMID: 20581111; PMCID: PMC2934687.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    37. The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology (Reading). 2010 Feb; 156(Pt 2):543-554. Milani CJE, Aziz RK, Locke JB, Dahesh S, Nizet V, Buchanan JT. PMID: 19762441; PMCID: PMC2890087.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    38. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 2009 Nov; 19(11):1204-13. Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. PMID: 19643844; PMCID: PMC2757575.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    39. Bacterial phenotype variants in group B streptococcal toxic shock syndrome. Emerg Infect Dis. 2009 Feb; 15(2):223-32. Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, Norrby-Teglund A. PMID: 19193266; PMCID: PMC2657631.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    40. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrob Agents Chemother. 2008 Aug; 52(8):2915-8. Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. PMID: 18541727; PMCID: PMC2493126.
      View in: PubMed   Mentions: 95     Fields:    Translation:Cells
    41. Protein folding kinetics provides a context-independent assessment of beta-strand propensity in the Fyn SH3 domain. J Mol Biol. 2007 Oct 26; 373(3):764-74. Zarrine-Afsar A, Dahesh S, Davidson AR. PMID: 17850820.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    42. Protein-protein interaction affinity plays a crucial role in controlling the Sho1p-mediated signal transduction pathway in yeast. Mol Cell. 2004 Jun 18; 14(6):813-23. Marles JA, Dahesh S, Haynes J, Andrews BJ, Davidson AR. PMID: 15200958.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
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