Charlotte Stoneham

Title(s)	Assistant Project Scientist, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0003-3729-6936
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Overview

Interests

Cellular Biology, Molecular Virology, Confocal Microscopy, Electron Microscopy, Mass Spectrometry, Proteomics, HIV-1, SARS-CoV2, Endocytosis, Clathrin Adaptor Proteins, Endosomal Sorting

Websites

ResearchGate Profile

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Reply to: Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nat Chem Biol. 2023 Nov; 19(11):1306-1308. Oh CK, Piña-Crespo J, Talantova M, Carnevale LN, Stoneham C, Lewinski M, Guatelli J, Lipton SA. PMID: 37798355.

View in: PubMed Mentions: Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation. Viruses. 2023 02 28; 15(3). Firrito C, Bertelli C, Rosa A, Chande A, Ananth S, van Dijk H, Fackler OT, Stoneham C, Singh R, Guatelli J, Pizzato M. PMID: 36992361; PMCID: PMC10057511.

View in: PubMed Mentions: 1 Fields:
Vir Virology
Translation:Humans Cells
Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression. Mol Cell Proteomics. 2022 03; 21(3):100194. Oom AL, Stoneham CA, Lewinski MK, Richards A, Wozniak JM, Shams-Ud-Doha K, Gonzalez DJ, Krogan NJ, Guatelli J. PMID: 35017099; PMCID: PMC8956815.

View in: PubMed Mentions: Fields:
Bio Biochemistry Cel Cell Biology Mol Molecular Biology
Translation:Humans Cells
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. PLoS Pathog. 2021 11; 17(11):e1009409. Stoneham CA, Langer S, De Jesus PD, Wozniak JM, Lapek J, Deerinck T, Thor A, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J. PMID: 34843601; PMCID: PMC8659692.

View in: PubMed Mentions: Fields:
Mic Microbiology
Translation:Humans Cells
Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. PLoS Pathog. 2021 05; 17(5):e1009519. Park SH, Siddiqi H, Castro DV, De Angelis AA, Oom AL, Stoneham CA, Lewinski MK, Clark AE, Croker BA, Carlin AF, Guatelli J, Opella SJ. PMID: 34003853; PMCID: PMC8184013.

View in: PubMed Mentions: 16 Fields:
Mic Microbiology
Translation:Humans Animals Cells
Functional landscape of SARS-CoV-2 cellular restriction. Mol Cell. 2021 06 17; 81(12):2656-2668.e8. Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Curry HM, Oom AL, Miorin L, Rodriguez-Frandsen A, Zheng F, Wu C, Xiong Y, Urbanowski M, Shaw ML, Chang MW, Benner C, Hope TJ, Frieman MB, García-Sastre A, Ideker T, Hultquist JF, Guatelli J, Chanda SK. PMID: 33930332; PMCID: PMC8043580.

View in: PubMed Mentions: 129 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
Corrigendum to "Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5" [Virology 2020 548, 73-81]. Virology. 2021 May; 557:100. Angerstein AO, Stoneham CA, Ramirez PW, Guatelli JC, Vollbrecht T. PMID: 33581863.

View in: PubMed Mentions: Fields:
Vir Virology
Functional Landscape of SARS-CoV-2 Cellular Restriction. bioRxiv. 2020 Sep 30. Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Pratt D, Churas C, Rosenthal SB, Liu S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Oom AL, Miorin L, Rodriguez-Frandsen A, Urbanowski M, Shaw ML, Chang MW, Benner C, Frieman MB, García-Sastre A, Ideker T, Hultquist JF, Guatelli J, Chanda SK. PMID: 33024967; PMCID: PMC7536870.

View in: PubMed Mentions:
Structural basis of CD4 downregulation by HIV-1 Nef. Nat Struct Mol Biol. 2020 09; 27(9):822-828. Kwon Y, Kaake RM, Echeverria I, Suarez M, Karimian Shamsabadi M, Stoneham C, Ramirez PW, Kress J, Singh R, Sali A, Krogan N, Guatelli J, Jia X. PMID: 32719457; PMCID: PMC7483821.

View in: PubMed Mentions: 30 Fields:
Mol Molecular Biology
Translation:Humans Cells
Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5. Virology. 2020 09; 548:73-81. Angerstein AO, Stoneham CA, Ramirez PW, Guatelli JC, Vollbrecht T. PMID: 32838948; PMCID: PMC7447835.

View in: PubMed Mentions: 3 Fields:
Vir Virology
Translation:Humans Cells
A Conserved Acidic-Cluster Motif in SERINC5 Confers Partial Resistance to Antagonism by HIV-1 Nef. J Virol. 2020 03 17; 94(7). Stoneham CA, Ramirez PW, Singh R, Suarez M, Debray A, Lim C, Jia X, Xiong Y, Guatelli J. PMID: 31941773; PMCID: PMC7081897.

View in: PubMed Mentions: 14 Fields:
Vir Virology
Translation:Humans Cells
Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins. Cells. 2019 09 02; 8(9). Ramirez PW, Sharma S, Singh R, Stoneham CA, Vollbrecht T, Guatelli J. PMID: 31480747; PMCID: PMC6770538.

View in: PubMed Mentions: 17 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
Next-generation of targeted AAVP vectors for systemic transgene delivery against cancer. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18571-18577. Suwan K, Yata T, Waramit S, Przystal JM, Stoneham CA, Bentayebi K, Asavarut P, Chongchai A, Pothachareon P, Lee KY, Topanurak S, Smith TL, Gelovani JG, Sidman RL, Pasqualini R, Arap W, Hajitou A. PMID: 31375630; PMCID: PMC6744886.

View in: PubMed Mentions: 21 Fields:
Sci Science
Translation:Humans Animals Cells
Phosphoserine acidic cluster motifs bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes. J Biol Chem. 2018 10 05; 293(40):15678-15690. Singh R, Stoneham C, Lim C, Jia X, Guenaga J, Wyatt R, Wertheim JO, Xiong Y, Guatelli J. PMID: 30135209; PMCID: PMC6177606.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Endocytic activity of HIV-1 Vpu: Phosphoserine-dependent interactions with clathrin adaptors. Traffic. 2017 08; 18(8):545-561. Stoneham CA, Singh R, Jia X, Xiong Y, Guatelli J. PMID: 28504462; PMCID: PMC5600163.

View in: PubMed Mentions: 10 Fields:
Phy Physiology
Translation:Humans Cells
Pharmacologic Inhibition of Nedd8 Activation Enzyme Exposes CD4-Induced Epitopes within Env on Cells Expressing HIV-1. J Virol. 2015 Dec 16; 90(5):2486-502. Tokarev A, Stoneham C, Lewinski MK, Mukim A, Deshmukh S, Vollbrecht T, Spina CA, Guatelli J. PMID: 26676780; PMCID: PMC4810708.

View in: PubMed Mentions: 8 Fields:
Vir Virology
Translation:Humans Cells
A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases. mBio. 2014 Aug 12; 5(4). Mousnier A, Schroeder GN, Stoneham CA, So EC, Garnett JA, Yu L, Matthews SJ, Choudhary JS, Hartland EL, Frankel G. PMID: 25118235; PMCID: PMC4145681.

View in: PubMed Mentions: 18 Fields:
Mic Microbiology
Translation:Humans Animals Cells
Enterohaemorrhagic Escherichia coli inhibits recycling endosome function and trafficking of surface receptors. Cell Microbiol. 2014 Nov; 16(11):1693-705. Clements A, Stoneham CA, Furniss RC, Frankel G. PMID: 24898821; PMCID: PMC4336558.

View in: PubMed Mentions: 7 Fields:
Cel Cell Biology Mic Microbiology
Translation:Humans Cells
The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice. Infect Immun. 2013 Jul; 81(7):2598-605. Harding CR, Stoneham CA, Schuelein R, Newton H, Oates CV, Hartland EL, Schroeder GN, Frankel G. PMID: 23649096; PMCID: PMC3697626.

View in: PubMed Mentions: 23 Fields:
All Allergy and Immunology Com Communicable Diseases
Translation:Animals Cells
Clathrin-mediated endocytosis and subsequent endo-lysosomal trafficking of adeno-associated virus/phage. J Biol Chem. 2012 Oct 19; 287(43):35849-59. Stoneham CA, Hollinshead M, Hajitou A. PMID: 22915587; PMCID: PMC3476254.

View in: PubMed Mentions: 30 Fields:
Bio Biochemistry
Translation:Humans Cells
Proteasome inhibition in cancer is associated with enhanced tumor targeting by the adeno-associated virus/phage. Mol Oncol. 2013 Feb; 7(1):55-66. Przystal JM, Umukoro E, Stoneham CA, Yata T, O'Neill K, Syed N, Hajitou A. PMID: 22951279; PMCID: PMC3553581.

View in: PubMed Mentions: 16 Fields:
Mol Molecular Biology Neo Neoplasms
Translation:Humans Animals Cells
The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways. Biomaterials. 2010 Mar; 31(9):2665-72. Griesenbach U, Meng C, Farley R, Wasowicz MY, Munkonge FM, Chan M, Stoneham C, Sumner-Jones SG, Pringle IA, Gill DR, Hyde SC, Stevenson B, Holder E, Ban H, Hasegawa M, Cheng SH, Scheule RK, Sinn PL, McCray PB, Alton EW. PMID: 20022367; PMCID: PMC4148698.

View in: PubMed Mentions: 6 Fields:
Bio Biomedical Engineering
Translation:Humans Animals Cells
A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol Cancer Ther. 2009 Aug; 8(8):2383-91. Trepel M, Stoneham CA, Eleftherohorinou H, Mazarakis ND, Pasqualini R, Arap W, Hajitou A. PMID: 19671758; PMCID: PMC2871293.

View in: PubMed Mentions: 32 Fields:
Ant Antineoplastic Agents
Translation:Humans Animals Cells
Flavonol tetraglycosides and other constituents from leaves of Styphnolobium japonicum (Leguminosae) and related taxa. Phytochemistry. 2007 May; 68(10):1407-16. Kite GC, Stoneham CA, Veitch NC. PMID: 17462679.

View in: PubMed Mentions: 10 Fields:
Bot Botany Che Chemistry
Translation:Animals
Application of liquid chromatography-mass spectrometry to the investigation of poisoning by Oenanthe crocata. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jun 21; 838(1):63-70. Kite GC, Stoneham CA, Veitch NC, Stein BK, Whitwell KE. PMID: 16730246.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Che Chemistry Techniques
Translation:Animals Cells