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Sonya Neal

Title(s)Assistant Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    The Discovery of Molecules and Mechanisms in ERAD Retrotranslocation Pathways
    NIH/NIGMS R35GM133565Aug 15, 2019 - Jun 30, 2024
    Role: Principal Investigator
    Discovering the machinery and mechanism of ERAD-M retrotranslocation
    NIH/NIGMS F32GM111024May 1, 2014 - Apr 30, 2017
    Role: Principal Investigator
    Characterization of redox-mediated protein in mitochondria
    NIH/NIGMS F31GM087108Jan 1, 2009 - Dec 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation. iScience. 2020 Aug 21; 23(9):101493. Neal S, Syau D, Nejatfard A, Nadeau S, Hampton RY. PMID: 32891886.
      View in: PubMed   Mentions:
    2. The role of rhomboid superfamily members in protein homeostasis: Mechanistic insight and physiological implications. Biochim Biophys Acta Mol Cell Res. 2020 Oct; 1867(10):118793. Kandel RR, Neal SE. PMID: 32645330.
      View in: PubMed   Mentions:    Fields:    
    3. Assays for protein retrotranslocation in ERAD. Methods Enzymol. 2019; 619:1-26. Neal S, Duttke SH, Hampton RY. PMID: 30910017.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 03 01; 69(5):915. Neal S, Jaeger PA, Duttke SH, Benner C, Glass CK, Ideker T, Hampton RY. PMID: 29499140.
      View in: PubMed   Mentions: 2     Fields:    
    5. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 01 18; 69(2):306-320.e4. Neal S, Jaeger PA, Duttke SH, Benner C, K Glass C, Ideker T, Hampton RY. PMID: 29351849.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    6. Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space. Mol Biol Cell. 2017 Oct 15; 28(21):2773-2785. Neal SE, Dabir DV, Wijaya J, Boon C, Koehler CM. PMID: 28814504.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    7. A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates. J Biol Chem. 2017 02 24; 292(8):3112-3128. Neal S, Mak R, Bennett EJ, Hampton R. PMID: 28077573.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    8. Direct and essential function for Hrd3 in ER-associated degradation. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):5934-9. Vashistha N, Neal SE, Singh A, Carroll SM, Hampton RY. PMID: 27170191.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    9. Mia40 Protein Serves as an Electron Sink in the Mia40-Erv1 Import Pathway. J Biol Chem. 2015 Aug 21; 290(34):20804-14. Neal SE, Dabir DV, Tienson HL, Horn DM, Glaeser K, Ogozalek Loo RR, Barrientos A, Koehler CM. PMID: 26085103.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    10. Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins. Mol Biol Cell. 2009 Aug; 20(15):3481-90. Tienson HL, Dabir DV, Neal SE, Loo R, Hasson SA, Boontheung P, Kim SK, Loo JA, Koehler CM. PMID: 19477928.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells