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Jonathan Pokorski

TitleAssociate Researcher
InstitutionUniversity of California San Diego
DepartmentNanoengineering
Address9500 Gilman Drive #0448
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Protein/Polymer Devices for Slow-Release of Immunotherapies to Treat Ovarian Cancer
    NIH/NIBIB R21EB024874Sep 5, 2017 - Jun 30, 2019
    Role: Principal Investigator
    Development of Protein-Displaying Peptide Hydrogels for Tissue Engineering
    NIH/NIBIB R00EB011530Feb 15, 2012 - Jan 31, 2015
    Role: Principal Investigator
    Development of Protein-Displaying Peptide Hydrogels for Tissue Engineering
    NIH/NIBIB K99EB011530Apr 1, 2010 - Mar 31, 2012
    Role: Principal Investigator
    Molecular Evoluation of Virus based Hydrogels for Cancer Therapy
    NIH/NCI F32CA130318Sep 15, 2007 - Sep 14, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pokorski J, Smith LE. "Click" Chemistry for Medicine and Biology. Mol Pharm. 2018 Aug 06; 15(8):2891. PMID: 30078333.
      View in: PubMed
    2. Hutnick MA, Pokorski J. Polymeric Interventions for Microbial Infections: A Review. Mol Pharm. 2018 May 22. PMID: 29787274.
      View in: PubMed
    3. Lee PW, Pokorski J. Poly(lactic-co-glycolic acid) devices: Production and applications for sustained protein delivery. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Mar 13. PMID: 29536634.
      View in: PubMed
    4. Czapar AE, Tiu BDB, Veliz FA, Pokorski J, Steinmetz NF. Slow-Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer. Adv Sci (Weinh). 2018 May; 5(5):1700991. PMID: 29876220.
      View in: PubMed
    5. Wallat JD, Harrison JK, Pokorski J. pH Responsive Doxorubicin Delivery by Fluorous Polymers for Cancer Treatment. Mol Pharm. 2018 Jan 30. PMID: 29381366.
      View in: PubMed
    6. Lee PW, Maia J, Pokorski J. Milling solid proteins to enhance activity after melt-encapsulation. Int J Pharm. 2017 Nov 25; 533(1):254-265. PMID: 28939464.
      View in: PubMed
    7. Lee PW, Shukla S, Wallat JD, Danda C, Steinmetz NF, Maia J, Pokorski J. Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing. ACS Nano. 2017 Sep 26; 11(9):8777-8789. PMID: 28902491.
      View in: PubMed
    8. Johansen ML, Gao Y, Hutnick MA, Craig SEL, Pokorski J, Flask CA, Brady-Kalnay SM. Quantitative Molecular Imaging with a Single Gd-Based Contrast Agent Reveals Specific Tumor Binding and Retention in Vivo. Anal Chem. 2017 Jun 06; 89(11):5932-5939. PMID: 28481080.
      View in: PubMed
    9. Kim SE, Lee PW, Pokorski J. Biologically Triggered Delivery of EGF from Polymer Fiber Patches. ACS Macro Lett. 2017; 6(6):593-597. PMID: 29250460.
      View in: PubMed
    10. Cyphert EL, Wallat JD, Pokorski J, von Recum HA. Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery. Antibiotics (Basel). 2017 Apr 25; 6(2). PMID: 28441360.
      View in: PubMed
    11. Tiu BD, Kernan DL, Tiu SB, Wen AM, Zheng Y, Pokorski J, Advincula RC, Steinmetz NF. Electrostatic layer-by-layer construction of fibrous TMV biofilms. Nanoscale. 2017 Jan 26; 9(4):1580-1590. PMID: 28070572.
      View in: PubMed
    12. Lee PW, Isarov SA, Wallat JD, Molugu SK, Shukla S, Sun JE, Zhang J, Zheng Y, Lucius Dougherty M, Konkolewicz D, Stewart PL, Steinmetz NF, Hore MJ, Pokorski J. Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates. J Am Chem Soc. 2017 03 08; 139(9):3312-3315. PMID: 28121424.
      View in: PubMed
    13. Hutnick MA, Ahsanuddin S, Guan L, Lam M, Baron ED, Pokorski J. PEGylated Dendrimers as Drug Delivery Vehicles for the Photosensitizer Silicon Phthalocyanine Pc 4 for Candidal Infections. Biomacromolecules. 2017 02 13; 18(2):379-385. PMID: 28117573.
      View in: PubMed
    14. Chen Q, Mangadlao JD, Wallat J, De Leon A, Pokorski J, Advincula RC. 3D Printing Biocompatible Polyurethane/Poly(lactic acid)/Graphene Oxide Nanocomposites: Anisotropic Properties. ACS Appl Mater Interfaces. 2017 Feb 01; 9(4):4015-4023. PMID: 28026926.
      View in: PubMed
    15. Wallat JD, Czapar AE, Wang C, Wen AM, Wek KS, Yu X, Steinmetz NF, Pokorski J. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules. 2017 01 09; 18(1):103-112. PMID: 27992176.
      View in: PubMed
    16. Chariou PL, Lee KL, Pokorski J, Saidel GM, Steinmetz NF. Diffusion and Uptake of Tobacco Mosaic Virus as Therapeutic Carrier in Tumor Tissue: Effect of Nanoparticle Aspect Ratio. J Phys Chem B. 2016 07 07; 120(26):6120-9. PMID: 27045770.
      View in: PubMed
    17. Kim SE, Zhang C, Advincula AA, Baer E, Pokorski J. Protein and Bacterial Antifouling Behavior of Melt-Coextruded Nanofiber Mats. ACS Appl Mater Interfaces. 2016 Apr 13; 8(14):8928-38. PMID: 27043205.
      View in: PubMed
    18. Isarov SA, Lee PW, Pokorski J. "Graft-to" Protein/Polymer Conjugates Using Polynorbornene Block Copolymers. Biomacromolecules. 2016 Feb 08; 17(2):641-8. PMID: 26765848.
      View in: PubMed
    19. Lee P, Towslee J, Maia J, Pokorski J. PEGylation to Improve Protein Stability During Melt Processing. Macromol Biosci. 2015 Oct; 15(10):1332-7. PMID: 26097064; PMCID: PMC4615555 [Available on 10/01/16].
    20. Kim SE, Wallat JD, Harker EC, Advincula AA, Pokorski J. Multifunctional and Spatially Controlled Bioconjugation to Melt Coextruded Nanofibers. Polym Chem. 2015 Aug 21; 6(31):5683-5692. PMID: 26604990.
      View in: PubMed
    21. Lee KL, Shukla S, Wu M, Ayat NR, El Sanadi CE, Wen AM, Edelbrock JF, Pokorski J, Commandeur U, Dubyak GR, Steinmetz NF. Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X. Acta Biomater. 2015 Jun; 19:166-79. PMID: 25769228; PMCID: PMC4411193.
    22. Kim SE, Harker EC, De Leon AC, Advincula RC, Pokorski J. Coextruded, aligned, and gradient-modified poly(e-caprolactone) fibers as platforms for neural growth. Biomacromolecules. 2015 Mar 09; 16(3):860-7. PMID: 25715836.
      View in: PubMed
    23. Herrmann K, Johansen ML, Craig SE, Vincent J, Howell M, Gao Y, Lu L, Erokwu B, Agnes RS, Lu ZR, Pokorski J, Basilion J, Gulani V, Griswold M, Flask C, Brady-Kalnay SM. Molecular Imaging of Tumors Using a Quantitative T 1 Mapping Technique via Magnetic Resonance Imaging. Diagnostics (Basel). 2015; 5(3):318-32. PMID: 26435847; PMCID: PMC4589153.
    24. Kim SE, Wang J, Jordan AM, Korley LT, Baer E, Pokorski J. Surface Modification of Melt Extruded Poly(e-caprolactone) Nanofibers: Toward a New Scalable Biomaterial Scaffold. ACS Macro Lett. 2014 Jun 17; 3(6):585-589. PMID: 24977107.
      View in: PubMed
    25. von Recum HA, Pokorski J. Peptide and protein-based inhibitors of HIV-1 co-receptors. Exp Biol Med (Maywood). 2013 May; 238(5):442-9. PMID: 23856897; PMCID: PMC3908444.
    26. Pokorski J, Appella DH. Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA. J Nucleic Acids. 2012; 2012:971581. PMID: 22957210; PMCID: PMC3432390.
    27. Wen AM, Ryan MJ, Yang AC, Breitenkamp K, Pokorski J, Steinmetz NF. Photodynamic activity of viral nanoparticles conjugated with C60. Chem Commun (Camb). 2012 Sep 18; 48(72):9044-6. PMID: 22858632; PMCID: PMC3470913.
    28. Nicolaou KC, Valiulin RA, Pokorski J, Chang V, Chen JS. Bio-inspired synthesis and biological evaluation of a colchicine-related compound library. Bioorg Med Chem Lett. 2012 Jun 01; 22(11):3776-80. PMID: 22542017; PMCID: PMC3353021.
    29. Pokorski J, Hovlid ML, Finn MG. Cell targeting with hybrid Qß virus-like particles displaying epidermal growth factor. Chembiochem. 2011 Nov 04; 12(16):2441-7. PMID: 21956837; PMCID: PMC3410710.
    30. Pokorski J, Breitenkamp K, Liepold LO, Qazi S, Finn MG. Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization. J Am Chem Soc. 2011 Jun 22; 133(24):9242-5. PMID: 21627118; PMCID: PMC3163106.
    31. Pokorski J, Steinmetz NF. The art of engineering viral nanoparticles. Mol Pharm. 2011 Feb 07; 8(1):29-43. PMID: 21047140; PMCID: PMC3156490.
    32. Pokorski J, Jenkins LM, Feng H, Durell SR, Bai Y, Appella DH. Introduction of a triazole amino acid into a peptoid oligomer induces turn formation in aqueous solution. Org Lett. 2007 Jun 07; 9(12):2381-3. PMID: 17506576.
      View in: PubMed
    33. Witschi MA, Pokorski J, Appella DH. Peptide nucleic acid microarrays made with (S,S)-trans-cyclopentane-constrained peptide nucleic acids. Methods Enzymol. 2006; 410:189-200. PMID: 16938552.
      View in: PubMed
    34. Guler MO, Pokorski J, Appella DH, Stupp SI. Enhanced oligonucleotide binding to self-assembled nanofibers. Bioconjug Chem. 2005 May-Jun; 16(3):501-3. PMID: 15898715.
      View in: PubMed
    35. Pokorski J, Nam JM, Vega RA, Mirkin CA, Appella DH. Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection. Chem Commun (Camb). 2005 Apr 28; (16):2101-3. PMID: 15846413.
      View in: PubMed
    36. Myers MC, Pokorski J, Appella DH. Peptide nucleic acids with a flexible secondary amine in the backbone maintain oligonucleotide binding affinity. Org Lett. 2004 Dec 09; 6(25):4699-702. PMID: 15575664.
      View in: PubMed
    37. Pokorski J, Witschi MA, Purnell BL, Appella DH. (S,S)-trans-cyclopentane-constrained peptide nucleic acids. a general backbone modification that improves binding affinity and sequence specificity. J Am Chem Soc. 2004 Nov 24; 126(46):15067-73. PMID: 15548003.
      View in: PubMed
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