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Stanley Opella

TitleResearcher
InstitutionUniversity of California San Diego
DepartmentChemistry and Biochemistry
Address9500 Gilman Drive #0307
La Jolla CA 92093
Phone858-822-4820
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    Collapse Research 
    Collapse Research Activities and Funding
    Structures, Dynamics, and Functions of Membrane Proteins
    NIH/NIGMS R35GM122501May 1, 2017 - Apr 30, 2022
    Role: Principal Investigator
    Structure Determination of Membrane Proteins in Phospholipid Bilyaers
    NIH/NIGMS R01GM099986Apr 1, 2012 - Mar 31, 2016
    Role: Principal Investigator
    Protein-Protein Interaction in Natural Product Biosynthesis
    NIH/NIGMS R01GM095970Mar 1, 2012 - Jan 31, 2020
    Role: Principal Investigator
    Acquisition of a Cryoprobe for an 800 MHz NMR Spectrometer
    NIH/NCRR S10RR023773Mar 1, 2008 - Feb 28, 2009
    Role: Principal Investigator
    Membrane Protein Structures in Phospholipid Bilayers by Solid State NMR
    NIH/NIGMS R01GM075877Sep 23, 2005 - Jul 31, 2011
    Role: Principal Investigator
    Molecular Imaging of G-Protein-Coupled Receptors for Drug Development
    NIH/NIBIB R01EB005161Apr 1, 2005 - Apr 30, 2015
    Role: Principal Investigator
    Structure, Dynamics, and Functions of the Viroporins Vpu from HIV and p7 from HCV
    NIH/NIGMS R01GM066978Jul 1, 2003 - Jul 31, 2017
    Role: Principal Investigator
    CONFERENCE ON FRONTIERS OF NMR IN MOLECULAR BIOLOGY VII
    NIH/NCI R13CA088925Mar 5, 2001 - Feb 28, 2002
    Role: Principal Investigator
    PHAGE DISPLAY--STRUCTURE, BIOLOGY AND APPLICATIONS
    NIH/NCI R13CA090984Sep 1, 2000 - Dec 31, 2003
    Role: Principal Investigator
    CONFERENCE ON FRONTIERS OF NMR IN MOLECULAR BIOLOGY
    NIH/NIDDK R13DK054982Jan 1, 1999 - Dec 31, 1999
    Role: Principal Investigator
    NMR PROBES FOR MEMBRANE PROTEIN STRUCTURE DETERMINATION
    NIH/NCRR R01RR012599Aug 1, 1998 - Mar 31, 2003
    Role: Principal Investigator
    STRUCTURAL BIOLOGY OF AIDS RELATED PROJECTS
    NIH/NIGMS P01GM056538Aug 1, 1997 - Nov 30, 2003
    Role: Principal Investigator
    Resource for NMR Molecular Imaging of Proteins
    NIH/NIBIB P41EB002031Apr 10, 1994 - May 31, 2019
    Role: Principal Investigator
    RESOURCE FOR SOLID STATE NMR OF PROTEINS
    NIH/NCRR P41RR009793Apr 10, 1994 - May 30, 2004
    Role: Principal Investigator
    PROTEIN STRUCTURE BY SOLID-STATE NMR SPECTROSCOPY
    NIH/NCRR R24RR005976Apr 1, 1991 - Mar 31, 1994
    Role: Principal Investigator
    NMR STRUCTURAL STUDIES OF MEMBRANE PROTEINS
    NIH/NIAID R01AI020770Dec 1, 1984 - Jun 30, 1998
    Role: Principal Investigator
    SOLID STATE NMR OF PEPTIDES
    NIH/NIBIB R01EB002169Jan 1, 1982 - Mar 31, 2006
    Role: Principal Investigator
    SOLID STATE NMR OF PEPTIDES
    NIH/NIGMS R01GM029754Jan 1, 1982 - Mar 31, 2005
    Role: Principal Investigator
    Consolidated Basic Cancer Research Program
    NIH P30CA010815Sep 1, 1978 - Feb 28, 2019
    Role: Co-Investigator
    NMR Studies of Biological Supramolecular Structures
    NIH/NIBIB R01EB001966Aug 1, 1977 - Feb 28, 2009
    Role: Principal Investigator
    NMR STUDIES OF BIOLOGICAL SUPRAMOLECULAR STRUCTURES
    NIH/NIGMS R37GM024266Aug 1, 1977 - Mar 31, 2004
    Role: Principal Investigator
    NMR STUDIES OF BIOLOGICAL SUPRAMOLECULAR STRUCTURES
    NIH/NIGMS R01GM024266Aug 1, 1977 - Jul 31, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Radoicic J, Park SH, Opella S. Macrodiscs Comprising SMALPs for Oriented Sample Solid-State NMR Spectroscopy of Membrane Proteins. Biophys J. 2018 Jun 15. PMID: 29914645.
      View in: PubMed
    2. McKay MJ, Martfeld AN, De Angelis AA, Opella S, Greathouse DV, Koeppe RE. Control of Transmembrane Helix Dynamics by Interfacial Tryptophan Residues. Biophys J. 2018 Jun 05; 114(11):2617-2629. PMID: 29874612.
      View in: PubMed
    3. Park SH, Berkamp S, Radoicic J, De Angelis AA, Opella S. Interaction of Monomeric Interleukin-8 with CXCR1 Mapped by Proton-Detected Fast MAS Solid-State NMR. Biophys J. 2017 Dec 19; 113(12):2695-2705. PMID: 29262362.
      View in: PubMed
    4. Berkamp S, Park SH, De Angelis AA, Marassi FM, Opella S. Structure of monomeric Interleukin-8 and its interactions with the N-terminal Binding Site-I of CXCR1 by solution NMR spectroscopy. J Biomol NMR. 2017 Nov; 69(3):111-121. PMID: 29143165.
      View in: PubMed
    5. Jaremko MJ, Lee DJ, Patel A, Winslow V, Opella S, McCammon JA, Burkart MD. Manipulating Protein-Protein Interactions in Nonribosomal Peptide Synthetase Type II Peptidyl Carrier Proteins. Biochemistry. 2017 10 10; 56(40):5269-5273. PMID: 28920687.
      View in: PubMed
    6. Amin A, Latif Z, Opella S. Expression and Purification of Transmembrane Protein MerE from Mercury Resistant Bacillus cereus. J Microbiol Biotechnol. 2017 Aug 08. PMID: 28783894.
      View in: PubMed
    7. Opella S, Marassi FM. Applications of NMR to membrane proteins. Arch Biochem Biophys. 2017 08 15; 628:92-101. PMID: 28529197.
      View in: PubMed
    8. Yao Y, Dutta SK, Park SH, Rai R, Fujimoto LM, Bobkov AA, Opella S, Marassi FM. High resolution solid-state NMR spectroscopy of the Yersinia pestis outer membrane protein Ail in lipid membranes. J Biomol NMR. 2017 03; 67(3):179-190. PMID: 28239773.
      View in: PubMed
    9. Tian Y, Schwieters CD, Opella S, Marassi FM. High quality NMR structures: a new force field with implicit water and membrane solvation for Xplor-NIH. J Biomol NMR. 2017 01; 67(1):35-49. PMID: 28035651.
      View in: PubMed
    10. Das BB, Opella S. Simultaneous cross polarization to (13)C and (15)N with (1)H detection at 60kHz MAS solid-state NMR. J Magn Reson. 2016 Jan; 262:20-26. PMID: 26705905; PMCID: PMC4716881 [Available on 01/01/17].
    11. Zhang H, Lin EC, Das BB, Tian Y, Opella S. Structural determination of virus protein U from HIV-1 by NMR in membrane environments. Biochim Biophys Acta. 2015 Nov; 1848(11 Pt A):3007-3018. PMID: 26362058; PMCID: PMC4623708 [Available on 11/01/16].
    12. Jaremko MJ, Lee DJ, Opella S, Burkart MD. Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. J Am Chem Soc. 2015 Sep 16; 137(36):11546-9. PMID: 26340431; PMCID: PMC4847951.
    13. Tian Y, Schwieters CD, Opella S, Marassi FM. A Practical Implicit Membrane Potential for NMR Structure Calculations of Membrane Proteins. Biophys J. 2015 Aug 04; 109(3):574-85. PMID: 26244739; PMCID: PMC4572468.
    14. Opella S. Relating structure and function of viral membrane-spanning miniproteins. Curr Opin Virol. 2015 Jun; 12:121-5. PMID: 26057606; PMCID: PMC4476644.
    15. Lewinski MK, Jafari M, Zhang H, Opella S, Guatelli J. Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly. J Biol Chem. 2015 Apr 24; 290(17):10919-33. PMID: 25759385; PMCID: PMC4409254.
    16. Opella S. Solid-state NMR and membrane proteins. J Magn Reson. 2015 Apr; 253:129-37. PMID: 25681966; PMCID: PMC4372479.
    17. Park SH, Wang VS, Radoicic J, De Angelis AA, Berkamp S, Opella S. Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl)propanoic acid (HQA). J Biomol NMR. 2015 Apr; 61(3-4):185-96. PMID: 25430059; PMCID: PMC4398598.
    18. Tian Y, Lu GJ, Marassi FM, Opella S. Structure of the membrane protein MerF, a bacterial mercury transporter, improved by the inclusion of chemical shift anisotropy constraints. J Biomol NMR. 2014 Sep; 60(1):67-71. PMID: 25103921; PMCID: PMC4154067.
    19. Radoicic J, Lu GJ, Opella S. NMR structures of membrane proteins in phospholipid bilayers. Q Rev Biophys. 2014 Aug; 47(3):249-83. PMID: 25032938; PMCID: PMC4153756.
    20. Wu CH, De Angelis AA, Opella S. Magic angle Lee-Goldburg frequency offset irradiation improves the efficiency and selectivity of SPECIFIC-CP in triple-resonance MAS solid-state NMR. J Magn Reson. 2014 Sep; 246:1-3. PMID: 25051542; PMCID: PMC4165850.
    21. Das BB, Opella S. Multiple acquisition/multiple observation separated local field/chemical shift correlation solid-state magic angle spinning NMR spectroscopy. J Magn Reson. 2014 Aug; 245:98-104. PMID: 25023566; PMCID: PMC4128693.
    22. Das BB, Park SH, Opella S. Membrane protein structure from rotational diffusion. Biochim Biophys Acta. 2015 Jan; 1848(1 Pt B):229-45. PMID: 24747039; PMCID: PMC4201901.
    23. Tian Y, Schwieters CD, Opella S, Marassi FM. A practical implicit solvent potential for NMR structure calculation. J Magn Reson. 2014 Jun; 243:54-64. PMID: 24747742; PMCID: PMC4037354.
    24. Lu GJ, Opella S. Mechanism of dilute-spin-exchange in solid-state NMR. J Chem Phys. 2014 Mar 28; 140(12):124201. PMID: 24697432; PMCID: PMC3971823.
    25. Das BB, Zhang H, Opella S. Dipolar Assisted Assignment Protocol (DAAP) for MAS solid-state NMR of rotationally aligned membrane proteins in phospholipid bilayers. J Magn Reson. 2014 May; 242:224-32. PMID: 24698983; PMCID: PMC4043445.
    26. Perrin BS, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella S, Pastor RW, Cotten ML. High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J Am Chem Soc. 2014 Mar 05; 136(9):3491-504. PMID: 24410116; PMCID: PMC3985945.
    27. Opella S. The development of solid-state NMR of membrane proteins. Biomed Spectrosc Imaging. 2014; 3(2):81-105. PMID: 26069880.
      View in: PubMed
    28. Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella S, Tsai SC, Burkart MD. Trapping the dynamic acyl carrier protein in fatty acid biosynthesis. Nature. 2014 Jan 16; 505(7483):427-31. PMID: 24362570; PMCID: PMC4437705.
    29. Lu GJ, Opella S. Resonance assignments of a membrane protein in phospholipid bilayers by combining multiple strategies of oriented sample solid-state NMR. J Biomol NMR. 2014 Jan; 58(1):69-81. PMID: 24356892; PMCID: PMC3928288.
    30. Lin EC, Opella S. Covariance spectroscopy in high-resolution multi-dimensional solid-state NMR. J Magn Reson. 2014 Feb; 239:57-60. PMID: 24380813; PMCID: PMC3929046.
    31. Gleason NJ, Greathouse DV, Grant CV, Opella S, Koeppe RE. Single tryptophan and tyrosine comparisons in the N-terminal and C-terminal interface regions of transmembrane GWALP peptides. J Phys Chem B. 2013 Nov 07; 117(44):13786-94. PMID: 24111589; PMCID: PMC3934079.
    32. Park SH, Yang C, Opella S, Mueller LJ. Resolution and measurement of heteronuclear dipolar couplings of a noncrystalline protein immobilized in a biological supramolecular assembly by proton-detected MAS solid-state NMR spectroscopy. J Magn Reson. 2013 Dec; 237:164-8. PMID: 24225529; PMCID: PMC3915937.
    33. Wang Y, Park SH, Tian Y, Opella S. Impact of histidine residues on the transmembrane helices of viroporins. Mol Membr Biol. 2013 Nov; 30(7):360-9. PMID: 24102567; PMCID: PMC4028331.
    34. Das BB, Lin EC, Opella S. Experiments optimized for magic angle spinning and oriented sample solid-state NMR of proteins. J Phys Chem B. 2013 Oct 17; 117(41):12422-31. PMID: 24044695; PMCID: PMC3846429.
    35. Lin EC, Opella S. Sampling scheme and compressed sensing applied to solid-state NMR spectroscopy. J Magn Reson. 2013 Dec; 237:40-8. PMID: 24140622; PMCID: PMC3851314.
    36. Lu GJ, Opella S. Motion-adapted pulse sequences for oriented sample (OS) solid-state NMR of biopolymers. J Chem Phys. 2013 Aug 28; 139(8):084203. PMID: 24006989; PMCID: PMC3772948.
    37. Cook GA, Dawson LA, Tian Y, Opella S. Three-dimensional structure and interaction studies of hepatitis C virus p7 in 1,2-dihexanoyl-sn-glycero-3-phosphocholine by solution nuclear magnetic resonance. Biochemistry. 2013 Aug 06; 52(31):5295-303. PMID: 23841474; PMCID: PMC3855088.
    38. Opella S. Structure determination of membrane proteins in their native phospholipid bilayer environment by rotationally aligned solid-state NMR spectroscopy. Acc Chem Res. 2013 Sep 17; 46(9):2145-53. PMID: 23829871; PMCID: PMC3778126.
    39. Lu GJ, Tian Y, Vora N, Marassi FM, Opella S. The structure of the mercury transporter MerF in phospholipid bilayers: a large conformational rearrangement results from N-terminal truncation. J Am Chem Soc. 2013 Jun 26; 135(25):9299-302. PMID: 23763519; PMCID: PMC3763827.
    40. Opella S. Structure determination of membrane proteins by nuclear magnetic resonance spectroscopy. Annu Rev Anal Chem (Palo Alto Calif). 2013; 6:305-28. PMID: 23577669; PMCID: PMC3980955.
    41. Yao Y, Ding Y, Tian Y, Opella S, Marassi FM. Membrane protein structure determination: back to the membrane. Methods Mol Biol. 2013; 1063:145-58. PMID: 23975776; PMCID: PMC4012560.
    42. Rankenberg JM, Vostrikov VV, Greathouse DV, Grant CV, Opella S, Koeppe RE. Properties of membrane-incorporated WALP peptides that are anchored on only one end. Biochemistry. 2012 Dec 18; 51(50):10066-74. PMID: 23171005; PMCID: PMC3527101.
    43. Park SH, Das BB, Casagrande F, Tian Y, Nothnagel HJ, Chu M, Kiefer H, Maier K, De Angelis AA, Marassi FM, Opella S. Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Nature. 2012 Nov 29; 491(7426):779-83. PMID: 23086146; PMCID: PMC3700570.
    44. Tian Y, Opella S, Marassi FM. Improved chemical shift prediction by Rosetta conformational sampling. J Biomol NMR. 2012 Nov; 54(3):237-43. PMID: 23007199; PMCID: PMC3484222.
    45. Lu GJ, Park SH, Opella S. Improved 1H amide resonance line narrowing in oriented sample solid-state NMR of membrane proteins in phospholipid bilayers. J Magn Reson. 2012 Jul; 220:54-61. PMID: 22683581; PMCID: PMC3760517.
    46. Rankenberg JM, Vostrikov VV, DuVall CD, Greathouse DV, Koeppe RE, Grant CV, Opella S. Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses. Biochemistry. 2012 May 01; 51(17):3554-64. PMID: 22489564; PMCID: PMC3558528.
    47. Gleason NJ, Vostrikov VV, Greathouse DV, Grant CV, Opella S, Koeppe RE. Tyrosine replacing tryptophan as an anchor in GWALP peptides. Biochemistry. 2012 Mar 13; 51(10):2044-53. PMID: 22364236; PMCID: PMC3312603.
    48. Das BB, Nothnagel HJ, Lu GJ, Son WS, Tian Y, Marassi FM, Opella S. Structure determination of a membrane protein in proteoliposomes. J Am Chem Soc. 2012 Feb 01; 134(4):2047-56. PMID: 22217388; PMCID: PMC3272072.
    49. Vostrikov VV, Grant CV, Opella S, Koeppe RE. On the combined analysis of ²H and ¹5N/¹H solid-state NMR data for determination of transmembrane peptide orientation and dynamics. Biophys J. 2011 Dec 21; 101(12):2939-47. PMID: 22208192; PMCID: PMC3244059.
    50. Skasko M, Wang Y, Tian Y, Tokarev A, Munguia J, Ruiz A, Stephens EB, Opella S, Guatelli J. HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions. J Biol Chem. 2012 Jan 02; 287(1):58-67. PMID: 22072710; PMCID: PMC3249111.
    51. Son WS, Park SH, Nothnagel HJ, Lu GJ, Wang Y, Zhang H, Cook GA, Howell SC, Opella S. 'q-Titration' of long-chain and short-chain lipids differentiates between structured and mobile residues of membrane proteins studied in bicelles by solution NMR spectroscopy. J Magn Reson. 2012 Jan; 214(1):111-8. PMID: 22079194; PMCID: PMC3257358.
    52. Park SH, Casagrande F, Chu M, Maier K, Kiefer H, Opella S. Optimization of purification and refolding of the human chemokine receptor CXCR1 improves the stability of proteoliposomes for structure determination. Biochim Biophys Acta. 2012 Mar; 1818(3):584-91. PMID: 22024025; PMCID: PMC3777732.
    53. Park SH, Casagrande F, Cho L, Albrecht L, Opella S. Interactions of interleukin-8 with the human chemokine receptor CXCR1 in phospholipid bilayers by NMR spectroscopy. J Mol Biol. 2011 Nov 25; 414(2):194-203. PMID: 22019593; PMCID: PMC3236022.
    54. Tian Y, Schwieters CD, Opella S, Marassi FM. AssignFit: a program for simultaneous assignment and structure refinement from solid-state NMR spectra. J Magn Reson. 2012 Jan; 214(1):42-50. PMID: 22036904; PMCID: PMC3257385.
    55. Park SH, Berkamp S, Cook GA, Chan MK, Viadiu H, Opella S. Nanodiscs versus macrodiscs for NMR of membrane proteins. Biochemistry. 2011 Oct 25; 50(42):8983-5. PMID: 21936505; PMCID: PMC3236031.
    56. Marassi FM, Das BB, Lu GJ, Nothnagel HJ, Park SH, Son WS, Tian Y, Opella S. Structure determination of membrane proteins in five easy pieces. Methods. 2011 Dec; 55(4):363-9. PMID: 21964394; PMCID: PMC3264820.
    57. De Angelis AA, Grant CV, Baxter MK, McGavin JA, Opella S, Cotten ML. Amphipathic antimicrobial piscidin in magnetically aligned lipid bilayers. Biophys J. 2011 Sep 07; 101(5):1086-94. PMID: 21889445; PMCID: PMC3164131.
    58. Lin EC, Opella S. 1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples. J Magn Reson. 2011 Jul; 211(1):37-44. PMID: 21543244; PMCID: PMC3236683.
    59. Park SH, Casagrande F, Das BB, Albrecht L, Chu M, Opella S. Local and global dynamics of the G protein-coupled receptor CXCR1. Biochemistry. 2011 Mar 29; 50(12):2371-80. PMID: 21323370; PMCID: PMC3236025.
    60. Haushalter RW, Filipp FV, Ko KS, Yu R, Opella S, Burkart MD. Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. ACS Chem Biol. 2011 May 20; 6(5):413-8. PMID: 21268653; PMCID: PMC3092034.
    61. Lu GJ, Son WS, Opella S. A general assignment method for oriented sample (OS) solid-state NMR of proteins based on the correlation of resonances through heteronuclear dipolar couplings in samples aligned parallel and perpendicular to the magnetic field. J Magn Reson. 2011 Apr; 209(2):195-206. PMID: 21316275; PMCID: PMC3109902.
    62. Cook GA, Stefer S, Opella S. Expression and purification of the membrane protein p7 from hepatitis C virus. Biopolymers. 2011; 96(1):32-40. PMID: 20560141; PMCID: PMC2954269.
    63. Park SH, Das BB, De Angelis AA, Scrima M, Opella S. Mechanically, magnetically, and "rotationally aligned" membrane proteins in phospholipid bilayers give equivalent angular constraints for NMR structure determination. J Phys Chem B. 2010 Nov 11; 114(44):13995-4003. PMID: 20961141; PMCID: PMC3760507.
    64. Park SH, Opella S. Triton X-100 as the "short-chain lipid" improves the magnetic alignment and stability of membrane proteins in phosphatidylcholine bilayers for oriented-sample solid-state NMR spectroscopy. J Am Chem Soc. 2010 Sep 15; 132(36):12552-3. PMID: 20735058; PMCID: PMC2958821.
    65. Park SH, Marassi FM, Black D, Opella S. Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. Biophys J. 2010 Sep 08; 99(5):1465-74. PMID: 20816058; PMCID: PMC2931714.
    66. Opella S. Perspectives in magnetic resonance. J Magn Reson. 2010 Sep; 206(1):1. PMID: 20727502.
      View in: PubMed
    67. Cook GA, Opella S. Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy. Biochim Biophys Acta. 2011 Jun; 1808(6):1448-53. PMID: 20727850; PMCID: PMC3046219.
    68. Cook GA, Zhang H, Park SH, Wang Y, Opella S. Comparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1. Biochim Biophys Acta. 2011 Feb; 1808(2):554-60. PMID: 20727848; PMCID: PMC3005007.
    69. Shealy P, Simin M, Park SH, Opella S, Valafar H. Simultaneous structure and dynamics of a membrane protein using REDCRAFT: membrane-bound form of Pf1 coat protein. J Magn Reson. 2010 Nov; 207(1):8-16. PMID: 20829084; PMCID: PMC3970221.
    70. Lin EC, Wu CH, Yang Y, Grant CV, Opella S. 1H-13C separated local field spectroscopy of uniformly 13C labeled peptides and proteins. J Magn Reson. 2010 Sep; 206(1):105-11. PMID: 20637662; PMCID: PMC2926282.
    71. Knox RW, Lu GJ, Opella S, Nevzorov AA. A resonance assignment method for oriented-sample solid-state NMR of proteins. J Am Chem Soc. 2010 Jun 23; 132(24):8255-7. PMID: 20509649; PMCID: PMC2909040.
    72. Grant CV, Wu CH, Opella S. Probes for high field solid-state NMR of lossy biological samples. J Magn Reson. 2010 Jun; 204(2):180-8. PMID: 20435493; PMCID: PMC2887343.
    73. Cook GA, Opella S. NMR studies of membrane proteins. Methods Mol Biol. 2010; 637:263-75. PMID: 20419440; PMCID: PMC3760502.
    74. Wu CH, Das BB, Opella S. (1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins. J Magn Reson. 2010 Feb; 202(2):127-34. PMID: 19896874; PMCID: PMC2888030.
    75. Park SH, Son WS, Mukhopadhyay R, Valafar H, Opella S. Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps. J Am Chem Soc. 2009 Oct 14; 131(40):14140-1. PMID: 19761238; PMCID: PMC2771775.
    76. Filipp FV, Sinha N, Jairam L, Bradley J, Opella S. Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins. J Magn Reson. 2009 Dec; 201(2):121-30. PMID: 19781966; PMCID: PMC2804798.
    77. Cook GA, Opella S. NMR studies of p7 protein from hepatitis C virus. Eur Biophys J. 2010 Jun; 39(7):1097-104. PMID: 19727701; PMCID: PMC2878448.
    78. Grant CV, Yang Y, Glibowicka M, Wu CH, Park SH, Deber CM, Opella S. A Modified Alderman-Grant Coil makes possible an efficient cross-coil probe for high field solid-state NMR of lossy biological samples. J Magn Reson. 2009 Nov; 201(1):87-92. PMID: 19733108; PMCID: PMC2800166.
    79. Wu CH, Grant CV, Cook GA, Park SH, Opella S. A strip-shield improves the efficiency of a solenoid coil in probes for high-field solid-state NMR of lossy biological samples. J Magn Reson. 2009 Sep; 200(1):74-80. PMID: 19559634; PMCID: PMC2741312.
    80. Opella S. Faster is better: improving the sensitivity of solid-state NMR. Nat Methods. 2009 Mar; 6(3):197-8. PMID: 19247292.
      View in: PubMed
    81. Diller A, Loudet C, Aussenac F, Raffard G, Fournier S, Laguerre M, Grélard A, Opella S, Marassi FM, Dufourc EJ. Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. Biochimie. 2009 Jun; 91(6):744-51. PMID: 19248817; PMCID: PMC2899883.
    82. Page RC, Lee S, Moore JD, Opella S, Cross TA. Backbone structure of a small helical integral membrane protein: A unique structural characterization. Protein Sci. 2009 Jan; 18(1):134-46. PMID: 19177358; PMCID: PMC2708045.
    83. Vostrikov VV, Grant CV, Daily AE, Opella S, Koeppe RE. Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment. J Am Chem Soc. 2008 Sep 24; 130(38):12584-5. PMID: 18763771; PMCID: PMC2609751.
    84. Park SH, Loudet C, Marassi FM, Dufourc EJ, Opella S. Solid-state NMR spectroscopy of a membrane protein in biphenyl phospholipid bicelles with the bilayer normal parallel to the magnetic field. J Magn Reson. 2008 Jul; 193(1):133-8. PMID: 18492613; PMCID: PMC2562692.
    85. Wu CH, Opella S. Shiftless nuclear magnetic resonance spectroscopy. J Chem Phys. 2008 Feb 07; 128(5):052312. PMID: 18266429; PMCID: PMC3760504.
    86. Opella S, Zeri AC, Park SH. Structure, dynamics, and assembly of filamentous bacteriophages by nuclear magnetic resonance spectroscopy. Annu Rev Phys Chem. 2008; 59:635-57. PMID: 18393681.
      View in: PubMed
    87. Sinha N, Filipp FV, Jairam L, Park SH, Bradley J, Opella S. Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins. Magn Reson Chem. 2007 Dec; 45 Suppl 1:S107-15. PMID: 18157808; PMCID: PMC5010364.
    88. Wu CH, Opella S. Proton-detected separated local field spectroscopy. J Magn Reson. 2008 Jan; 190(1):165-70. PMID: 17981481; PMCID: PMC3486921.
    89. Müller SD, De Angelis AA, Walther TH, Grage SL, Lange C, Opella S, Ulrich AS. Structural characterization of the pore forming protein TatAd of the twin-arginine translocase in membranes by solid-state 15N-NMR. Biochim Biophys Acta. 2007 Dec; 1768(12):3071-9. PMID: 17980349.
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