Sotirios Tsimikas

Title(s)Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Oxidation-specific nanoparticles for imaging atherosclerosis
    NIH R01HL119828Aug 21, 2013 - Jul 31, 2019
    Role: Principal Investigator
    IMAGING ATHEROSCLEROSIS WITH SPECIFIC ANTIBODIES
    NIH K08HL003793Dec 15, 1997 - Nov 30, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Defining the Role of Lp(a) in High-Risk Plaques: The Road to Validation of IVUS, NIRS, OCT, and CTA Approaches. Circ Cardiovasc Imaging. 2024 Nov; 17(11):e017613. Tsimikas S. PMID: 39561227.
      View in: PubMed   Mentions:    Fields:    
    2. Independence of Lipoprotein(a) and Low-Density Lipoprotein Cholesterol-Mediated Cardiovascular Risk: A Participant-Level Meta-Analysis. Circulation. 2024 Nov 04. Bhatia HS, Wandel S, Willeit P, Lesogor A, Bailey K, Ridker PM, Nestel P, Simes J, Tonkin A, Schwartz GG, Colhoun H, Wanner C, Tsimikas S. PMID: 39492722.
      View in: PubMed   Mentions:    Fields:    
    3. The Effects of Colchicine on Lipoprotein(a) and Oxidized Phospholipid Associated Cardiovascular Disease Risk. Eur J Prev Cardiol. 2024 Oct 30. Mohammadnia N, van Broekhoven A, Bax WA, Eikelboom JW, Mosterd A, Fiolet ATL, Tijssen JGP, Thompson PL, de Kleijn DPV, Tsimikas S, Cornel JH, Yeang C, El Messaoudi S. PMID: 39478683.
      View in: PubMed   Mentions:    Fields:    
    4. Polygenic risk, aspirin and primary prevention of coronary artery disease. Eur Heart J Cardiovasc Pharmacother. 2024 Oct 25. Yu C, Natarajan P, Patel AP, Bhatia HS, Khera AV, Neumann JT, Tsimikas S, Wolfe R, Nicholls SJ, Reid CM, Zoungas S, Tonkin AM, McNeil JJ, Lacaze P. PMID: 39455425.
      View in: PubMed   Mentions:    Fields:    
    5. Oxidized Phospholipids and Calcific Aortic Valvular Disease. J Am Coll Cardiol. 2024 Oct 22. Bhatia HS, Dweck MR, Craig N, Capoulade R, Pibarot P, Trainor PJ, Whelton SP, Rikhi R, Lidani KCF, Post WS, Tsai MY, Criqui MH, Shapiro MD, Budoff MJ, DeFilippis AP, Thanassoulis G, Tsimikas S. PMID: 39545902.
      View in: PubMed   Mentions:    Fields:    
    6. Efficacy and safety of olezarsen in lowering apolipoprotein C-III and triglycerides in healthy Japanese Americans. Lipids Health Dis. 2024 Oct 03; 23(1):329. Karwatowska-Prokopczuk E, Lesogor A, Yan JH, Hoenlinger A, Margolskee A, Li L, Tsimikas S. PMID: 39363329; PMCID: PMC11448427.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    7. Lp(a) and Accelerated Progression of Aortic Stenosis: A Rationale for Universal Measurement and Therapeutic Targeting. JACC Asia. 2024 Oct; 4(10):761-763. Tsimikas S. PMID: 39553910; PMCID: PMC11561483.
      View in: PubMed   Mentions:
    8. Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression: A Systematic Review and Meta-Analysis. JAMA Cardiol. 2024 Sep 01; 9(9):835-842. Arsenault BJ, Loganath K, Girard A, Botezatu S, Zheng KH, Tzolos E, Abdoun K, Tastet L, Capoulade R, Côté N, Craig N, Chan KL, Tam JW, Teo KK, Couture C, Clavel MA, Mathieu P, Thériault S, Stroes ESG, Newby DE, Tsimikas S, Pibarot P, Dweck MR. PMID: 39018080; PMCID: PMC11255972.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. In Search of an Accurate Measurement of LDL-C: Correction for Lp(a)-Cholesterol to Predict Clinical Outcomes. J Am Coll Cardiol. 2024 Jul 09; 84(2):178-181. Tsimikas S, Yeang C, Kronenberg F. PMID: 38960511.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Lipoprotein(a) in the Year 2024: A Look Back and a Look Ahead. Arterioscler Thromb Vasc Biol. 2024 07; 44(7):1485-1490. Tsimikas S. PMID: 38924439; PMCID: PMC11210685.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    11. Associations between lipoprotein(a), oxidized phospholipids, and extracoronary vascular disease. J Lipid Res. 2024 Jul; 65(7):100585. Bellomo TR, Liu Y, Gilliland TC, Miksenas H, Haidermota S, Wong M, Hu X, Cristino JR, Browne A, Plutzky J, Tsimikas S, Januzzi JL, Natarajan P. PMID: 38942114; PMCID: PMC11298641.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Lipoprotein(a), Oxidized Phospholipids, and Progression to Symptomatic Heart Failure: The CASABLANCA Study. J Am Heart Assoc. 2024 Jun 18; 13(12):e034774. Januzzi JL, van Kimmenade RRJ, Liu Y, Hu X, Browne A, Plutzky J, Tsimikas S, Blankstein R, Natarajan P. PMID: 38860394; PMCID: PMC11255745.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Aspirin use for primary prevention among US adults with and without elevated Lipoprotein(a). Am J Prev Cardiol. 2024 Jun; 18:100674. Razavi AC, Richardson LC, Coronado F, Dzaye O, Bhatia HS, Mehta A, Quyyumi AA, Vaccarino V, Budoff MJ, Nasir K, Tsimikas S, Whelton SP, Blaha MJ, Blumenthal RS, Sperling LS. PMID: 38741703; PMCID: PMC11090055.
      View in: PubMed   Mentions: 1  
    14. Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome. N Engl J Med. 2024 May 16; 390(19):1781-1792. Stroes ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, Arca M, Ballantyne CM, Soran H, Prohaska TA, Xia S, Ginsberg HN, Witztum JL, Tsimikas S, Balance Investigators. PMID: 38587247.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    15. Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk. N Engl J Med. 2024 May 16; 390(19):1770-1780. Bergmark BA, Marston NA, Prohaska TA, Alexander VJ, Zimerman A, Moura FA, Murphy SA, Goodrich EL, Zhang S, Gaudet D, Karwatowska-Prokopczuk E, Tsimikas S, Giugliano RP, Sabatine MS, Bridge–TIMI 73a Investigators. PMID: 38587249.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    16. Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis. J Clin Invest. 2024 Mar 01; 134(5). Nakamura Y, Kulkarni NN, Takahashi T, Alimohamadi H, Dokoshi T, Liu E, Shia M, Numata T, Luo EW, Gombart AF, Yang X, Secrest P, Gordts PL, Tsimikas S, Wong GC, Gallo RL. PMID: 38194294; PMCID: PMC10904043.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    17. Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial. PLoS One. 2024; 19(2):e0299197. Tomazini BM, Tramujas L, Medrado FA, Gomes SPDC, Negrelli KL, Murinize GS, Santos RHN, Vianna BMP, Piotto BF, Veiga TS, Santos BRD, Peneluppi Horak AC, Lemos OMC, Lopes MA, Olicheski BB, Campones DL, Peixoto LAA, Basilio ADAC, Gebara OCE, Lopes ATA, Saconato H, Valeis N, Miranda TA, Laranjeira LN, Santucci EV, Carlin AF, Esko JD, Gordts PLSM, Tsimikas S, Cavalcanti AB. PMID: 38394069; PMCID: PMC10889621.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    18. Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance. Cardiovasc Res. 2024 02 17; 119(18):2843-2857. Packard CJ, Pirillo A, Tsimikas S, Ference BA, Catapano AL. PMID: 38039351; PMCID: PMC11484501.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia. N Engl J Med. 2024 Feb 01; 390(5):476-477. Alexander VJ, Karwatowska-Prokopczuk E, Prohaska TA, Li L, Geary RS, Gouni-Berthold I, Oral EA, Hegele RA, Stroes ESG, Witztum JL, Tsimikas S. PMID: 38294982.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    20. Aspirin and Cardiovascular Risk in Individuals With Elevated Lipoprotein(a): The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2024 Feb 06; 13(3):e033562. Bhatia HS, Trainor P, Carlisle S, Tsai MY, Criqui MH, DeFilippis A, Tsimikas S. PMID: 38293935; PMCID: PMC11056170.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation. Arterioscler Thromb Vasc Biol. 2024 03; 44(3):720-740. Dzobo KE, Cupido AJ, Mol BM, Stiekema LCA, Versloot M, Winkelmeijer M, Peter J, Pennekamp AM, Havik SR, Vaz FM, van Weeghel M, Prange KHM, Levels JHM, de Winther MPJ, Tsimikas S, Groen AK, Stroes ESG, de Kleijn DPV, Kroon J. PMID: 38269588; PMCID: PMC10880937.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. Particle Number and Characteristics of Lipoprotein(a), LDL, and apoB: Perspectives on Contributions to ASCVD. J Am Coll Cardiol. 2024 01 23; 83(3):396-400. Tsimikas S, Bittner V. PMID: 38233013.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Safety and Tolerability of GalNAc3-Conjugated Antisense Drugs Compared to the Same-Sequence 2'-O-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data. Nucleic Acid Ther. 2024 02; 34(1):18-25. Baker BF, Xia S, Partridge W, Engelhardt JA, Tsimikas S, Crooke ST, Bhanot S, Geary RS. PMID: 38227794.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    24. Atherothrombotic and thrombolytic biomarkers in incident stroke and atrial fibrillation-related stroke: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2024 Mar; 390:117451. Lidani KCF, Trainor PJ, Bhatia HS, Nasir K, Blaha MJ, Tsai MY, Gottesman RF, Post WS, Thanassoulis G, Tsimikas S, Heckbert SR, DeFilippis AP. PMID: 38262276.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Effect of Eplontersen on Cardiac Structure and Function in Patients With Hereditary Transthyretin Amyloidosis. J Card Fail. 2024 Aug; 30(8):973-980. Masri A, Maurer MS, Claggett BL, Kulac I, Waddington Cruz M, Conceição I, Weiler M, Berk JL, Gertz M, Gillmore JD, Rush S, Chen J, Zhou W, Kwoh J, Duran JM, Tsimikas S, Solomon SD. PMID: 38065307.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Updated Lipoprotein(a) Genomic Risk Score and Aspirin for Primary Prevention of Cardiovascular Events. JACC Adv. 2024 Jan; 3(1):100754. Yu C, Thanassoulis G, Wolfe R, McNeil JJ, Tonkin AM, Tsimikas S, Lacaze P. PMID: 38939824; PMCID: PMC11198050.
      View in: PubMed   Mentions:
    27. Author Correction: Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease. Nat Cardiovasc Res. 2023 Dec; 2(12):1328. Pattarabanjird T, Nguyen AT, McSkimming C, Dinh HQ, Marshall MA, Ghosheh Y, Gulati R, Durant C, Vallejo J, Saigusa R, Drago F, Guy TV, Premo K, Taylor AM, Paul S, Kundu B, Berr S, Gonen A, Tsimikas S, Miller Y, Pillai S, Ley K, Hedrick CC, McNamara CA. PMID: 39196158.
      View in: PubMed   Mentions:
    28. Lipoprotein(a) levels and carotid intima-media thickness in children: A 20-year follow-up study. J Clin Lipidol. 2024 Mar-Apr; 18(2):e290-e294. de Boer LM, Hutten BA, Tsimikas S, Yeang C, Zwinderman AH, Kroon J, Revers A, Kastelein JJP, Wiegman A. PMID: 38065715.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Lipoprotein(a), platelet function and cardiovascular disease. Nat Rev Cardiol. 2024 05; 21(5):299-311. Bhatia HS, Becker RC, Leibundgut G, Patel M, Lacaze P, Tonkin A, Narula J, Tsimikas S. PMID: 37938756; PMCID: PMC11216952.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease. Circulation. 2024 01 30; 149(5):391-401. Rogers MA, Bartoli-Leonard F, Zheng KH, Small AM, Chen HY, Clift CL, Asano T, Kuraoka S, Blaser MC, Perez KA, Natarajan P, Yeang C, Stroes ESG, Tsimikas S, Engert JC, Thanassoulis G, O'Donnell CJ, Aikawa M, Singh SA, Aikawa E. PMID: 37937463; PMCID: PMC10842618.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease. Nat Cardiovasc Res. 2023 Nov; 2(11):1003-1014. Pattarabanjird T, Nguyen AT, McSkimming C, Dinh HQ, Marshall MA, Ghosheh Y, Gulati R, Durant C, Vallejo J, Saigusa R, Drago F, Guy TV, Premo K, Taylor AM, Paul S, Kundu B, Berr S, Gonen A, Tsimikas S, Miller Y, Pillai S, Ley K, Hedrick CC, McNamara CA. PMID: 39196097.
      View in: PubMed   Mentions: Translation:HumansAnimalsCells
    32. Oxidized phospholipids in cardiovascular disease. Nat Rev Cardiol. 2024 03; 21(3):170-191. Tsimikas S, Witztum JL. PMID: 37848630.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Corrigendum to "Volanesorsen and triglyceride levels in familial chylomicronemia syndrome: Long-term efficacy and safety data from patients in an open-label extension trial" [Journal of Clinical Lipidology, Volume 17, Issue 3, May-June 2023, Pages 342-355]. J Clin Lipidol. 2024 May-Jun; 18(3):e482-e483. Witztum JL, Gaudet D, Arca M, Jones A, Soran H, Gouni-Berthold I, Stroes ESG, Alexander VJ, Jones R, Watts L, Xia S, Tsimikas S. PMID: 38565460.
      View in: PubMed   Mentions:    Fields:    
    34. Relating Lipoprotein(a) Concentrations to Cardiovascular Event Risk After Acute Coronary Syndrome: A Comparison of 3 Tests. Circulation. 2024 01 16; 149(3):192-203. Szarek M, Reijnders E, Jukema JW, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, Ruhaak LR, Schwertfeger M, Tsimikas S, White HD, Steg PG, Cobbaert C, Schwartz GG, ODYSSEY OUTCOMES Investigators. PMID: 37632469; PMCID: PMC10782942.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Lipoprotein(a) and the pooled cohort equations for ASCVD risk prediction: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2023 09; 381:117217. Bhatia HS, Rikhi R, Allen TS, Yeang C, Guan W, Garg PK, Tsai MY, Criqui MH, Shapiro MD, Tsimikas S. PMID: 37607461; PMCID: PMC10659123.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Lipoprotein(a) and carotid intima-media thickness in children with familial hypercholesterolaemia in the Netherlands: a 20-year follow-up study. Lancet Diabetes Endocrinol. 2023 09; 11(9):667-674. de Boer LM, Wiegman A, Kroon J, Tsimikas S, Yeang C, Peletier MC, Revers A, Kastelein JJP, Zwinderman AH, Hutten BA. PMID: 37487514.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Reducing reductionism: addressing risk for atherosclerotic cardiovascular disease by apolipoprotein proteomics. Eur Heart J. 2023 Jul 14; 44(27):2420-2422. Schmidt LE, Speidl WS, Tsimikas S, Mayr M. PMID: 37264561.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Clinical trials to improve outcomes in patients with elevated Lp(a) undergoing PCI: The time has arrived. J Clin Lipidol. 2023 Sep-Oct; 17(5):567-570. Tsimikas S, Bhatia HS, Erlinge D. PMID: 37419784.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. On-treatment platelet reactivity through the thromboxane A2 or P2Y12 platelet receptor pathways is not affected by pelacarsen. J Thromb Thrombolysis. 2023 Aug; 56(2):226-232. Karwatowska-Prokopczuk E, Li L, Yang J, Witztum JL, Tsimikas S. PMID: 37338713.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    40. Lipoprotein(a) and coronary artery calcium in comparison with other lipid biomarkers: The multi-ethnic study of atherosclerosis. J Clin Lipidol. 2023 Jul-Aug; 17(4):538-548. Jackson CL, Garg PK, Guan W, Tsai MY, Criqui MH, Tsimikas S, Bhatia HS. PMID: 37357049; PMCID: PMC10691212.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nat Rev Cardiol. 2023 Jun; 20(6):429. Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A, Zhou F, Moreira AL, Côté N, Tsimikas S, Fuster V, Gandy S, Bonow RO, Gursky O, Narula J. PMID: 36807395.
      View in: PubMed   Mentions:    Fields:    
    42. High immunoglobulin-M levels to oxidation-specific epitopes are associated with lower risk of acute myocardial infarction. J Lipid Res. 2023 06; 64(6):100391. Taleb A, Willeit P, Amir S, Perkmann T, Kozma MO, Watzenböck ML, Binder CJ, Witztum JL, Tsimikas S. PMID: 37211249; PMCID: PMC10275726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Effects of mixed nut consumption on LDL cholesterol, lipoprotein(a), and other cardiometabolic risk factors in overweight and obese adults. Nutr Metab Cardiovasc Dis. 2023 Aug; 33(8):1529-1538. Nora CL, Zhang L, Castro RJ, Marx A, Carman HB, Lum T, Tsimikas S, Hong MY. PMID: 37263914.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    44. Lipoprotein(a), Oxidized Phospholipids, and Coronary Artery Disease Severity and Outcomes. J Am Coll Cardiol. 2023 05 09; 81(18):1780-1792. Gilliland TC, Liu Y, Mohebi R, Miksenas H, Haidermota S, Wong M, Hu X, Cristino JR, Browne A, Plutzky J, Tsimikas S, Januzzi JL, Natarajan P. PMID: 37137588; PMCID: PMC10824318.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    45. APOC3 inhibition with volanesorsen reduces hepatic steatosis in patients with severe hypertriglyceridemia. J Clin Lipidol. 2023 May-Jun; 17(3):406-411. Prohaska TA, Alexander VJ, Karwatowska-Prokopczuk E, Tami J, Xia S, Witztum JL, Tsimikas S. PMID: 37164837.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    46. Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification. Circulation. 2023 05 16; 147(20):1518-1533. Gollmann-Tepeköylü C, Graber M, Hirsch J, Mair S, Naschberger A, Pölzl L, Nägele F, Kirchmair E, Degenhart G, Demetz E, Hilbe R, Chen HY, Engert JC, Böhm A, Franz N, Lobenwein D, Lener D, Fuchs C, Weihs A, Töchterle S, Vogel GF, Schweiger V, Eder J, Pietschmann P, Seifert M, Kronenberg F, Coassin S, Blumer M, Hackl H, Meyer D, Feuchtner G, Kirchmair R, Troppmair J, Krane M, Weiss G, Tsimikas S, Thanassoulis G, Grimm M, Rupp B, Huber LA, Zhang SY, Casanova JL, Tancevski I, Holfeld J. PMID: 37013819; PMCID: PMC10192061.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    47. Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2023 04 04; 81(13):1248-1259. Trainor PJ, Brambatti M, Carlisle SM, Mullick AE, Shah SJ, Kahlon T, Mostacero DO, Mousavi H, Morgan ES, Tami Y, Michos ED, Ouyang P, Tsimikas S, DeFilippis AP. PMID: 36990544; PMCID: PMC10352958.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    48. Impact of C-reactive protein levels on lipoprotein(a)-associated aortic stenosis incidence and progression. Eur Heart J Open. 2023 Mar; 3(2):oead032. Girard A, Gaillard E, Puri R, Capoulade R, Chan KL, Paulin A, Manikpurage HD, Dumesnil J, Tam JW, Teo KK, Couture C, Wareham NJ, Clavel MA, Stroes ESG, Mathieu P, Thériault S, Tsimikas S, Pibarot P, Boekholdt SM, Arsenault BJ. PMID: 37077580; PMCID: PMC10108885.
      View in: PubMed   Mentions: 2  
    49. Volanesorsen and triglyceride levels in familial chylomicronemia syndrome: Long-term efficacy and safety data from patients in an open-label extension trial. J Clin Lipidol. 2023 May-Jun; 17(3):342-355. Witztum JL, Gaudet D, Arca M, Jones A, Soran H, Gouni-Berthold I, Stroes ESG, Alexander VJ, Jones R, Watts L, Xia S, Tsimikas S. PMID: 37100699.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    50. The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nat Rev Cardiol. 2023 06; 20(6):418-428. Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A, Zhou F, Moreira AL, Côté N, Tsimikas S, Fuster V, Gandy S, Bonow RO, Gursky O, Narula J. PMID: 36624274; PMCID: PMC10199673.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Association of Lp(a) (Lipoprotein[a]) and Hypertension in Primary Prevention of Cardiovascular Disease: The MESA. Hypertension. 2023 02; 80(2):352-360. Rikhi R, Bhatia HS, Schaich CL, Ashburn N, Tsai MY, Michos ED, Chevli PA, Herrington DM, Tsimikas S, Shapiro MD. PMID: 36511156; PMCID: PMC9983733.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    52. Efficacy and safety of pelacarsen in lowering Lp(a) in healthy Japanese subjects. J Clin Lipidol. 2023 Jan-Feb; 17(1):181-188. Karwatowska-Prokopczuk E, Lesogor A, Yan JH, Hurh E, Hoenlinger A, Margolskee A, Xia S, Tsimikas S. PMID: 36529659.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    53. Integrated Assessment of Phase 2 Data on GalNAc3-Conjugated 2'-O-Methoxyethyl-Modified Antisense Oligonucleotides. Nucleic Acid Ther. 2023 01; 33(1):72-80. Baker BF, Xia S, Partridge W, Kwoh TJ, Tsimikas S, Bhanot S, Geary RS. PMID: 36454263; PMCID: PMC10623620.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    54. Lipoprotein(a) and LDL-C: The Relevance of Equivalence. J Am Coll Cardiol. 2022 11 22; 80(21):2011-2013. Morris PB, Narula J, Tsimikas S. PMID: 36396202.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation. Lipids Health Dis. 2022 Nov 01; 21(1):113. Ruder S, Mansfield B, Immelman AR, Varki N, Miu P, Raal F, Tsimikas S. PMID: 36320028; PMCID: PMC9623907.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    56. Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes. J Am Coll Cardiol. 2022 10 04; 80(14):1287-1298. Lacaze P, Bakshi A, Riaz M, Polekhina G, Owen A, Bhatia HS, Natarajan P, Wolfe R, Beilin L, Nicholls SJ, Watts GF, McNeil JJ, Tonkin AM, Tsimikas S. PMID: 36175048; PMCID: PMC10025998.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    57. Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease. Open Heart. 2022 10; 9(2). Nissen SE, Wolski K, Cho L, Nicholls SJ, Kastelein J, Leitersdorf E, Landmesser U, Blaha M, Lincoff AM, Morishita R, Tsimikas S, Liu J, Manning B, Kozlovski P, Lesogor A, Thuren T, Shibasaki T, Matei F, Silveira FS, Meunch A, Bada A, Vijan V, Bruun NE, Nordestgaard BG, Lp(a)HERITAGE Investigators. PMID: 36252994; PMCID: PMC9577925.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    58. Assessment of efficacy and safety of volanesorsen for treatment of metabolic complications in patients with familial partial lipodystrophy: Results of the BROADEN study: Volanesorsen in FPLD; The BROADEN Study. J Clin Lipidol. 2022 Nov-Dec; 16(6):833-849. Oral EA, Garg A, Tami J, Huang EA, O'Dea LSL, Schmidt H, Tiulpakov A, Mertens A, Alexander VJ, Watts L, Hurh E, Witztum JL, Geary RS, Tsimikas S. PMID: 36402670.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    59. Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 08 30; 80(9):934-946. Tsimikas S, Marcovina SM. PMID: 36007992.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    60. Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering. JCI Insight. 2022 07 08; 7(13). Ramms B, Patel S, Sun X, Pessentheiner AR, Ducasa GM, Mullick AE, Lee RG, Crooke RM, Tsimikas S, Witztum JL, Gordts PL. PMID: 35653195; PMCID: PMC9310539.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    61. Oxidized phospholipids on apolipoprotein B-100 versus plasminogen and risk of coronary heart disease in the PROCARDIS study. Atherosclerosis. 2022 08; 354:15-22. Clarke R, Hammami I, Sherliker P, Valdes-Marquez E, Watkins H, Hill M, Yang X, Tsimikas S, Hopewell JC, PROCARDIS Consortium. PMID: 35803063.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    62. Effect of olezarsen targeting APOC-III on lipoprotein size and particle number measured by NMR in patients with hypertriglyceridemia. J Clin Lipidol. 2022 Sep-Oct; 16(5):617-625. Karwatowska-Prokopczuk E, Tardif JC, Gaudet D, Ballantyne CM, Shapiro MD, Moriarty PM, Baum SJ, Amour ES, Alexander VJ, Xia S, Otvos JD, Witztum JL, Tsimikas S, Olezarsen Trial Investigators. PMID: 35902351.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    63. Development and validation of an isoform-independent monoclonal antibody-based ELISA for measurement of lipoprotein(a). J Lipid Res. 2022 08; 63(8):100239. Marcovina SM, Navabi N, Allen S, Gonen A, Witztum JL, Tsimikas S. PMID: 35688187; PMCID: PMC9352967.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    64. Apolipoprotein C-III reduction in subjects with moderate hypertriglyceridaemia and at high cardiovascular risk. Eur Heart J. 2022 04 06; 43(14):1401-1412. Tardif JC, Karwatowska-Prokopczuk E, Amour ES, Ballantyne CM, Shapiro MD, Moriarty PM, Baum SJ, Hurh E, Bartlett VJ, Kingsbury J, Figueroa AL, Alexander VJ, Tami J, Witztum JL, Geary RS, O'Dea LSL, Tsimikas S, Gaudet D. PMID: 35025993; PMCID: PMC8986458.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    65. Effect of Pelacarsen on Lipoprotein(a) Cholesterol and Corrected Low-Density Lipoprotein Cholesterol. J Am Coll Cardiol. 2022 03 22; 79(11):1035-1046. Yeang C, Karwatowska-Prokopczuk E, Su F, Dinh B, Xia S, Witztum JL, Tsimikas S. PMID: 35300814; PMCID: PMC8972555.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    66. Atherothrombotic factors and atherosclerotic cardiovascular events: the multi-ethnic study of atherosclerosis. Eur Heart J. 2022 03 07; 43(10):971-981. DeFilippis AP, Trainor PJ, Thanassoulis G, Brumback LC, Post WS, Tsai MY, Tsimikas S. PMID: 34508626; PMCID: PMC8899529.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    67. Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial. Atherosclerosis. 2022 04; 346:68-74. Ren S, Hansbro PM, Srikusalanukul W, Horvat JC, Hunter T, Brown AC, Peel R, Faulkner J, Evans TJ, Li SC, Newby D, Hure A, Abhayaratna WP, Tsimikas S, Gonen A, Witztum JL, Attia J, AUSPICE investigators. PMID: 35290813.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    68. Lipoprotein(a) and Coronary Calcium: Clinical Management and Potential Design of Primary Prevention Trials. J Am Coll Cardiol. 2022 03 01; 79(8):769-771. Tsimikas S. PMID: 35210031.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    69. Trends in testing and prevalence of elevated Lp(a) among patients with aortic valve stenosis. Atherosclerosis. 2022 05; 349:144-150. Bhatia HS, Ma GS, Taleb A, Wilkinson M, Kahn AM, Cotter B, Yeang C, DeMaria AN, Patel MP, Mahmud E, Reeves RR, Tsimikas S. PMID: 35144769; PMCID: PMC9674369.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    70. Lipoprotein(a) and CT Angiography: Novel Insights Into High-Risk Plaque Progression. J Am Coll Cardiol. 2022 01 25; 79(3):234-237. Tsimikas S, Narula J. PMID: 35057908.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    71. Lipoprotein(a), venous thromboembolism and COVID-19: A pilot study. Atherosclerosis. 2022 01; 341:43-49. Nurmohamed NS, Collard D, Reeskamp LF, Kaiser Y, Kroon J, Tromp TR, Amsterdam UMC Covid-19 Biobank, van den Born BH, Coppens M, Vlaar APJ, Beudel M, van de Beek D, van Es N, Moriarty PM, Tsimikas S, Stroes ESG. PMID: 34995986; PMCID: PMC8690577.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    72. Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. Circulation. 2021 12 14; 144(24):1940-1954. Dou H, Kotini A, Liu W, Fidler T, Endo-Umeda K, Sun X, Olszewska M, Xiao T, Abramowicz S, Yalcinkaya M, Hardaway B, Tsimikas S, Que X, Bick A, Emdin C, Natarajan P, Papapetrou EP, Witztum JL, Wang N, Tall AR. PMID: 34846914; PMCID: PMC8663540.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    73. Longitudinal Assessment of Lipoprotein(a) Levels in Perinatally HIV-Infected Children and Adolescents. Viruses. 2021 10 14; 13(10). van Genderen JG, Van den Hof M, de Boer CG, Jansen HPG, van Deventer SJH, Tsimikas S, Witztum JL, Kastelein JJP, Pajkrt D. PMID: 34696496; PMCID: PMC8539147.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    74. PCSK9 Activity Is Potentiated Through HDL Binding. Circ Res. 2021 11 12; 129(11):1039-1053. Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE, Hall WL, Notdurfter M, Rungger G, Paulweber B, Willeit J, Kiechl S, Levkau B, Mayr M. PMID: 34601896; PMCID: PMC8579991.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    75. Always Present, But Now Rediscovered: Lp(a) as a Predictor of Long-Term Outcomes in PCI. JACC Cardiovasc Interv. 2021 09 27; 14(18):2069-2072. Tsimikas S, Reeves RR, Patel MP. PMID: 34556281.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    76. PCSK9 Inhibition and Oxidized Phospholipids. J Am Coll Cardiol. 2021 09 21; 78(12):1288-1289. Bhatia HS, Yeang C, Baruch A, Yang X, Stroes ESG, Tsimikas S. PMID: 34531030; PMCID: PMC10198455.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    77. Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. Aging Cell. 2021 08; 20(8):e13442. Palmieri M, Almeida M, Nookaew I, Gomez-Acevedo H, Joseph TE, Que X, Tsimikas S, Sun X, Manolagas SC, Witztum JL, Ambrogini E. PMID: 34278710; PMCID: PMC8373359.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    78. Association of lipoprotein(a) with intrinsic and on-clopidogrel platelet reactivity. J Thromb Thrombolysis. 2022 Jan; 53(1):1-9. Kille A, Nührenberg T, Franke K, Valina CM, Leibundgut G, Tsimikas S, Neumann FJ, Hochholzer W. PMID: 34213715; PMCID: PMC8791920.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    79. Elevated lipoprotein(a) and the risk of stroke in children, young adults, and the elderly. Eur Heart J. 2021 06 07; 42(22):2197-2200. Tsimikas S. PMID: 34000000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    80. Antisense Inhibition of Angiotensinogen With IONIS-AGT-LRx: Results of Phase 1 and Phase 2 Studies. JACC Basic Transl Sci. 2021 Jun; 6(6):485-496. Morgan ES, Tami Y, Hu K, Brambatti M, Mullick AE, Geary RS, Bakris GL, Tsimikas S. PMID: 34222719; PMCID: PMC8246029.
      View in: PubMed   Mentions: 15  
    81. Emerging RNA Therapeutics to Lower Blood Levels of Lp(a): JACC Focus Seminar 2/4. J Am Coll Cardiol. 2021 03 30; 77(12):1576-1589. Tsimikas S, Moriarty PM, Stroes ES. PMID: 33766265.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    82. Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol. 2021 05; 9(5):264-275. Gouni-Berthold I, Alexander VJ, Yang Q, Hurh E, Steinhagen-Thiessen E, Moriarty PM, Hughes SG, Gaudet D, Hegele RA, O'Dea LSL, Stroes ESG, Tsimikas S, Witztum JL, COMPASS study group. PMID: 33798466.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCTClinical Trials
    83. Prevalence and influence of LPA gene variants and isoform size on the Lp(a)-lowering effect of pelacarsen. Atherosclerosis. 2021 05; 324:102-108. Karwatowska-Prokopczuk E, Clouet-Foraison N, Xia S, Viney NJ, Witztum JL, Marcovina SM, Tsimikas S. PMID: 33872986.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    84. The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26. Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697; PMCID: PMC8010724.
      View in: PubMed   Mentions: 3  
    85. Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy. Neurol Ther. 2021 Jun; 10(1):375-389. Coelho T, Ando Y, Benson MD, Berk JL, Waddington-Cruz M, Dyck PJ, Gillmore JD, Khella SL, Litchy WJ, Obici L, Monteiro C, Tai LJ, Viney NJ, Buchele G, Brambatti M, Jung SW, St L O'Dea L, Tsimikas S, Schneider E, Geary RS, Monia BP, Gertz M. PMID: 33638113; PMCID: PMC8140170.
      View in: PubMed   Mentions: 22  
    86. Novel method for quantification of lipoprotein(a)-cholesterol: implications for improving accuracy of LDL-C measurements. J Lipid Res. 2021; 62:100053. Yeang C, Witztum JL, Tsimikas S. PMID: 33636163; PMCID: PMC8042377.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    87. Glucose Control in Patients Undergoing PCI: What Is the Optimal HbA1c for Long-Term Outcomes? JACC Cardiovasc Interv. 2021 02 22; 14(4):398-400. Tsimikas S, Bhatia HS. PMID: 33602436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    88. Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):e82-e96. Choi SH, Agatisa-Boyle C, Gonen A, Kim A, Kim J, Alekseeva E, Tsimikas S, Miller YI. PMID: 33356389; PMCID: PMC8105271.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    89. Effect of bariatric surgery on plasma levels of oxidised phospholipids, biomarkers of oxidised LDL and lipoprotein(a). J Clin Lipidol. 2021 Mar-Apr; 15(2):320-331. Ho JH, Adam S, Liu Y, Azmi S, Dhage S, Syed AA, Ammori BJ, Donn R, Heald A, Gibson MJ, Malik RA, Yang X, Durrington PN, Tsimikas S, Soran H. PMID: 33518459.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    90. Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data. ESC Heart Fail. 2021 02; 8(1):652-661. Viney NJ, Guo S, Tai LJ, Baker BF, Aghajan M, Jung SW, Yu RZ, Booten S, Murray H, Machemer T, Burel S, Murray S, Buchele G, Tsimikas S, Schneider E, Geary RS, Benson MD, Monia BP. PMID: 33283485; PMCID: PMC7835591.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCTClinical Trials
    91. microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production. JCI Insight. 2020 12 03; 5(23). Dong J, He M, Li J, Pessentheiner A, Wang C, Zhang J, Sun Y, Wang WT, Zhang Y, Liu J, Wang SC, Huang PH, Gordts PL, Yuan ZY, Tsimikas S, Shyy JY. PMID: 33119548; PMCID: PMC7714402.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    92. The interconnection between lipoprotein(a), lipoprotein(a) cholesterol and true LDL-cholesterol in the diagnosis of familial hypercholesterolemia. Curr Opin Lipidol. 2020 Dec; 31(6):305-312. Yeang C, Willeit P, Tsimikas S. PMID: 33027223.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    93. Low-Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events. J Am Heart Assoc. 2020 12; 9(23):e016318. Willeit P, Yeang C, Moriarty PM, Tschiderer L, Varvel SA, McConnell JP, Tsimikas S. PMID: 33222611; PMCID: PMC7763787.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    94. Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial. Eur Heart J. 2020 11 21; 41(44):4245-4255. Szarek M, Bittner VA, Aylward P, Baccara-Dinet M, Bhatt DL, Diaz R, Fras Z, Goodman SG, Halvorsen S, Harrington RA, Jukema JW, Moriarty PM, Pordy R, Ray KK, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Investigators. PMID: 33051646; PMCID: PMC7724642.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    95. Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):458-464. Hoekstra M, Chen HY, Rong J, Dufresne L, Yao J, Guo X, Tsai MY, Tsimikas S, Post WS, Vasan RS, Rotter JI, Larson MG, Thanassoulis G, Engert JC. PMID: 33115273; PMCID: PMC7769958.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    96. Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia. Eur Heart J. 2020 10 21; 41(40):3936-3945. Gaudet D, Karwatowska-Prokopczuk E, Baum SJ, Hurh E, Kingsbury J, Bartlett VJ, Figueroa AL, Piscitelli P, Singleton W, Witztum JL, Geary RS, Tsimikas S, O'Dea LSL, Vupanorsen Study Investigators. PMID: 32860031; PMCID: PMC7750927.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCTClinical Trials
    97. From traditional pharmacological towards nucleic acid-based therapies for cardiovascular diseases. Eur Heart J. 2020 10 21; 41(40):3884-3899. Landmesser U, Poller W, Tsimikas S, Most P, Paneni F, Lüscher TF. PMID: 32350510.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    98. A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice. J Bone Miner Res. 2021 01; 36(1):170-185. Palmieri M, Kim HN, Gomez-Acevedo H, Que X, Tsimikas S, Jilka RL, Manolagas SC, Witztum JL, Ambrogini E. PMID: 32990984; PMCID: PMC7855899.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    99. Lipoprotein(a) and Its Potential Association with Thrombosis and Inflammation in COVID-19: a Testable Hypothesis. Curr Atheroscler Rep. 2020 07 25; 22(9):48. Moriarty PM, Gorby LK, Stroes ES, Kastelein JP, Davidson M, Tsimikas S. PMID: 32710255; PMCID: PMC7381416.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCellsPHPublic Health
    100. Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a). J Lipid Res. 2020 Sep; 61(9):1263-1270. Gonen A, Yang X, Yeang C, Alekseeva E, Koschinsky M, Witztum JL, Boffa M, Tsimikas S. PMID: 32641432; PMCID: PMC7469883.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    101. Treatment with Volanesorsen, a 2'-O-Methoxyethyl-Modified Antisense Oligonucleotide Targeting APOC3 mRNA, Does Not Affect the QTc Interval in Healthy Volunteers. Nucleic Acid Ther. 2020 08; 30(4):198-206. Watts LM, Karwatowska-Prokopczuk E, Hurh E, Alexander VJ, Balogh K, O'Dea L, Geary RS, Tsimikas S. PMID: 32589506; PMCID: PMC7415887.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    102. Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a). Eur Heart J. 2020 06 21; 41(24):2262-2271. Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. PMID: 32268367; PMCID: PMC7308540.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    103. Statin therapy increases lipoprotein(a) levels. Eur Heart J. 2020 06 21; 41(24):2275-2284. Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31111151.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    104. Lipoprotein(a) Reduction in Persons with Cardiovascular Disease. Reply. N Engl J Med. 2020 05 21; 382(21):e65. Tsimikas S, Karwatowska-Prokopczuk E, Xia S. PMID: 32433854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    105. Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes. Int J Cardiol. 2020 09 15; 315:81-85. Schnitzler JG, Poels K, Stiekema LCA, Yeang C, Tsimikas S, Kroon J, Stroes ESG, Lutgens E, Seijkens TTP. PMID: 32387421.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    106. High-Density Lipoproteins Are the Main Carriers of PCSK9 in the Circulation. J Am Coll Cardiol. 2020 03 31; 75(12):1495-1497. Burnap SA, Joshi A, Tsimikas S, Fernández-Hernando C, Kiechl S, Berry SE, Hall W, Levkau B, Mayr M. PMID: 32216920.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    107. The dedicated "Lp(a) clinic": A concept whose time has arrived? Atherosclerosis. 2020 05; 300:1-9. Tsimikas S, Stroes ESG. PMID: 32234580.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    108. Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation. Circ Res. 2020 05 08; 126(10):1346-1359. Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. PMID: 32160811; PMCID: PMC7208285.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    109. ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis. Heart. 2020 05; 106(10):738-745. Capoulade R, Torzewski M, Mayr M, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam J, Teo KK, Burnap SA, Schmid J, Gobel N, Franke UFW, Sanchez A, Witztum JL, Yang X, Yeang C, Arsenault B, Després JP, Pibarot P, Tsimikas S. PMID: 32054669.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    110. Ancient Remedy for a Modern Disease: Will Celastrol Become a Treatment for Aortic Valve Stenosis? JACC Basic Transl Sci. 2020 Jan; 5(1):50-52. Yeang C, Tsimikas S. PMID: 32043488; PMCID: PMC7000881.
      View in: PubMed   Mentions: 2  
    111. Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome. J Am Coll Cardiol. 2020 01 21; 75(2):133-144. Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Committees and Investigators. PMID: 31948641.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    112. Familial hypercholesterolemia and elevated lipoprotein(a): double heritable risk and new therapeutic opportunities. J Intern Med. 2020 01; 287(1):2-18. Vuorio A, Watts GF, Schneider WJ, Tsimikas S, Kovanen PT. PMID: 31858669.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    113. Statins and increases in Lp(a): an inconvenient truth that needs attention. Eur Heart J. 2020 01 01; 41(1):192-193. Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31893480.
      View in: PubMed   Mentions: 11     Fields:    
    114. Lipoprotein(a) Reduction in Persons with Cardiovascular Disease. N Engl J Med. 2020 01 16; 382(3):244-255. Tsimikas S, Karwatowska-Prokopczuk E, Gouni-Berthold I, Tardif JC, Baum SJ, Steinhagen-Thiessen E, Shapiro MD, Stroes ES, Moriarty PM, Nordestgaard BG, Xia S, Guerriero J, Viney NJ, O'Dea L, Witztum JL, AKCEA-APO(a)-LRx Study Investigators. PMID: 31893580.
      View in: PubMed   Mentions: 253     Fields:    Translation:HumansCTClinical Trials
    115. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metab. 2020 01 07; 31(1):189-206.e8. Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. PMID: 31761566; PMCID: PMC7028360.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    116. Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial. Circulation. 2020 02 25; 141(8):624-636. Damask A, Steg PG, Schwartz GG, Szarek M, Hagström E, Badimon L, Chapman MJ, Boileau C, Tsimikas S, Ginsberg HN, Banerjee P, Manvelian G, Pordy R, Hess S, Overton JD, Lotta LA, Yancopoulos GD, Abecasis GR, Baras A, Paulding C, Regeneron Genetics Center and the ODYSSEY OUTCOMES Investigators. PMID: 31707832.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    117. Erratum: A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 Nov; 60(11):1979. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 31676683; PMCID: PMC6824499.
      View in: PubMed   Mentions:    Fields:    
    118. Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis. Circ Res. 2019 10 25; 125(10):e55-e70. Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen A, McSkimming C, Marshall MA, Garmey JC, Taylor AM, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, McNamara CA. PMID: 31549940; PMCID: PMC6830526.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    119. Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis. J Lipid Res. 2019 12; 60(12):2082-2089. Boffa MB, Marar TT, Yeang C, Viney NJ, Xia S, Witztum JL, Koschinsky ML, Tsimikas S. PMID: 31551368; PMCID: PMC6889713.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    120. PCSK9 loss-of-function variants and Lp(a) phenotypes among black US adults. J Lipid Res. 2019 11; 60(11):1946-1952. Mefford MT, Marcovina SM, Bittner V, Cushman M, Brown TM, Farkouh ME, Tsimikas S, Monda KL, López JAG, Muntner P, Rosenson RS. PMID: 31511398; PMCID: PMC6824493.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    121. Elevated Lipoprotein(a) in Perinatally HIV-Infected Children Compared With Healthy Ethnicity-Matched Controls. Open Forum Infect Dis. 2019 Sep; 6(9):ofz301. Van den Hof M, Klein Haneveld MJ, Blokhuis C, Scherpbier HJ, Jansen HPG, Kootstra NA, Dallinga-Thie GM, Van Deventer SJH, Tsimikas S, Pajkrt D, NOVICE study group . PMID: 31660394; PMCID: PMC6736182.
      View in: PubMed   Mentions: 6  
    122. N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels. Eur Heart J. 2019 09 01; 40(33):2785-2796. Alexander VJ, Xia S, Hurh E, Hughes SG, O'Dea L, Geary RS, Witztum JL, Tsimikas S. PMID: 31329855; PMCID: PMC6736334.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCTClinical Trials
    123. The challenges of measuring Lp(a): A fight against Hydra? Atherosclerosis. 2019 10; 289:181-183. Kronenberg F, Tsimikas S. PMID: 31495537.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    124. Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome. N Engl J Med. 2019 08 08; 381(6):531-542. Witztum JL, Gaudet D, Freedman SD, Alexander VJ, Digenio A, Williams KR, Yang Q, Hughes SG, Geary RS, Arca M, Stroes ESG, Bergeron J, Soran H, Civeira F, Hemphill L, Tsimikas S, Blom DJ, O'Dea L, Bruckert E. PMID: 31390500.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansCTClinical Trials
    125. ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance. J Lipid Res. 2019 08; 60(8):1379-1395. Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM. PMID: 31092690; PMCID: PMC6672034.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    126. Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis. J Am Coll Cardiol. 2019 05 07; 73(17):2150-2162. Zheng KH, Tsimikas S, Pawade T, Kroon J, Jenkins WSA, Doris MK, White AC, Timmers NKLM, Hjortnaes J, Rogers MA, Aikawa E, Arsenault BJ, Witztum JL, Newby DE, Koschinsky ML, Fayad ZA, Stroes ESG, Boekholdt SM, Dweck MR. PMID: 31047003; PMCID: PMC6494952.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    127. Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography. CJC Open. 2019 May; 1(3):131-140. Després AA, Perrot N, Poulin A, Tastet L, Shen M, Chen HY, Bourgeois R, Trottier M, Tessier M, Guimond J, Nadeau M, Engert JC, Thériault S, Bossé Y, Witztum JL, Couture P, Mathieu P, Dweck MR, Tsimikas S, Thanassoulis G, Pibarot P, Clavel MA, Arsenault BJ. PMID: 32159096; PMCID: PMC7063623.
      View in: PubMed   Mentions: 23  
    128. In Search of Patients With Elevated Lp(a): Seek and Ye Shall Find. J Am Coll Cardiol. 2019 03 12; 73(9):1040-1042. Tsimikas S. PMID: 30846098.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    129. Potential Causality and Emerging Medical Therapies for Lipoprotein(a) and Its Associated Oxidized Phospholipids in Calcific Aortic Valve Stenosis. Circ Res. 2019 02; 124(3):405-415. Tsimikas S. PMID: 30702993; PMCID: PMC6361547.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    130. Lipid-Lowering Agents. Circ Res. 2019 02; 124(3):386-404. Hegele RA, Tsimikas S. PMID: 30702996.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    131. Lipoprotein(a) in Patients Undergoing Transcatheter Aortic Valve Replacement. Angiology. 2019 Apr; 70(4):332-336. Ma GS, Wilkinson MJ, Reeves RR, Yeang C, DeMaria AN, Cotter B, Patel M, Mahmud E, Tsimikas S. PMID: 30700108.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    132. Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids. Cardiovasc Res. 2019 01 01; 115(1):179-189. Yeang C, Hasanally D, Que X, Hung MY, Stamenkovic A, Chan D, Chaudhary R, Margulets V, Edel AL, Hoshijima M, Gu Y, Bradford W, Dalton N, Miu P, Cheung DY, Jassal DS, Pierce GN, Peterson KL, Kirshenbaum LA, Witztum JL, Tsimikas S, Ravandi A. PMID: 29850765; PMCID: PMC6302283.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    133. Integrated Assessment of the Clinical Performance of GalNAc3-Conjugated 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer Experience. Nucleic Acid Ther. 2019 02; 29(1):16-32. Crooke ST, Baker BF, Xia S, Yu RZ, Viney NJ, Wang Y, Tsimikas S, Geary RS. PMID: 30570431; PMCID: PMC6386089.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCellsCTClinical Trials
    134. A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 02; 60(2):436-445. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 30563909; PMCID: PMC6358287.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    135. Association of Mild to Moderate Aortic Valve Stenosis Progression With Higher Lipoprotein(a) and Oxidized Phospholipid Levels: Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2018 12 01; 3(12):1212-1217. Capoulade R, Yeang C, Chan KL, Pibarot P, Tsimikas S. PMID: 30476957; PMCID: PMC6583098.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    136. RNA-targeted therapeutics for lipid disorders. Curr Opin Lipidol. 2018 12; 29(6):459-466. Tsimikas S. PMID: 30234555.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    137. Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis. JACC Cardiovasc Imaging. 2019 10; 12(10):2015-2026. Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C. PMID: 30343086; PMCID: PMC6461528.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    138. Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials. Lancet. 2018 10 13; 392(10155):1311-1320. Willeit P, Ridker PM, Nestel PJ, Simes J, Tonkin AM, Pedersen TR, Schwartz GG, Olsson AG, Colhoun HM, Kronenberg F, Drechsler C, Wanner C, Mora S, Lesogor A, Tsimikas S. PMID: 30293769.
      View in: PubMed   Mentions: 152     Fields:    Translation:Humans
    139. Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 09; 561(7724):E43. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 30013121.
      View in: PubMed   Mentions: 2     Fields:    
    140. Relationship of lipoprotein-associated apolipoprotein C-III with lipid variables and coronary artery disease risk: The EPIC-Norfolk prospective population study. J Clin Lipidol. 2018 Nov - Dec; 12(6):1493-1501.e11. van Capelleveen JC, Lee SR, Verbeek R, Kastelein JJP, Wareham NJ, Stroes ESG, Hovingh GK, Khaw KT, Boekholdt SM, Witztum JL, Tsimikas S. PMID: 30249512; PMCID: PMC6970616.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    141. Relationship of lipoprotein(a) molar concentrations and mass according to lipoprotein(a) thresholds and apolipoprotein(a) isoform size. J Clin Lipidol. 2018 Sep - Oct; 12(5):1313-1323. Tsimikas S, Fazio S, Viney NJ, Xia S, Witztum JL, Marcovina SM. PMID: 30100157.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    142. Lipoprotein Apheresis Acutely Reverses Coronary Microvascular Dysfunction in Patients With Severe Hypercholesterolemia. JACC Cardiovasc Imaging. 2019 08; 12(8 Pt 1):1430-1440. Wu MD, Moccetti F, Brown E, Davidson BP, Atkinson T, Belcik JT, Giraud G, Duell PB, Fazio S, Tavori H, Tsimikas S, Lindner JR. PMID: 29909101; PMCID: PMC6458098.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    143. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 06; 558(7709):301-306. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 29875409; PMCID: PMC6033669.
      View in: PubMed   Mentions: 204     Fields:    Translation:AnimalsCells
    144. Oxidation-specific epitopes restrain bone formation. Nat Commun. 2018 06 06; 9(1):2193. Ambrogini E, Que X, Wang S, Yamaguchi F, Weinstein RS, Tsimikas S, Manolagas SC, Witztum JL, Jilka RL. PMID: 29875355; PMCID: PMC5990540.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    145. Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):E4680-E4689. Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, Tremblay MS, Glass CK. PMID: 29632203; PMCID: PMC5960280.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    146. In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes. J Lipid Res. 2018 05; 59(5):741-744. Tsimikas S. PMID: 29610122; PMCID: PMC5928428.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    147. Relationship between "LDL-C", estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide. J Clin Lipidol. 2018 May - Jun; 12(3):702-710. Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. PMID: 29574075.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    148. PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis. J Am Coll Cardiol. 2018 01 23; 71(3):321-335. Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S. PMID: 29348025; PMCID: PMC5995462.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    149. Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease. J Cardiovasc Transl Res. 2018 06; 11(3):221-229. Kothari H, Nguyen AT, Yang X, Hisada Y, Tsimikas S, Mackman N, Taylor A, McNamara CA. PMID: 29344841.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    150. NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis. J Am Coll Cardiol. 2018 01 16; 71(2):177-192. Tsimikas S, Fazio S, Ferdinand KC, Ginsberg HN, Koschinsky ML, Marcovina SM, Moriarty PM, Rader DJ, Remaley AT, Reyes-Soffer G, Santos RD, Thanassoulis G, Witztum JL, Danthi S, Olive M, Liu L. PMID: 29325642; PMCID: PMC5868960.
      View in: PubMed   Mentions: 145     Fields:    Translation:Humans
    151. Interleukin-1 genotypes modulate the long-term effect of lipoprotein(a) on cardiovascular events: The Ioannina Study. J Clin Lipidol. 2018 Mar - Apr; 12(2):338-347. Naka KK, Bechlioullis A, Marini A, Sionis D, Vakalis K, Triantis G, Wilkins L, Rogus J, Kornman KS, Witztum JL, Doucette-Stamm L, Michalis LK, Tsimikas S. PMID: 29310992.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    152. Plasma Proteomics for Epidemiology: Increasing Throughput With Standard-Flow Rates. Circ Cardiovasc Genet. 2017 Dec; 10(6). Yin X, Baig F, Haudebourg E, Blankley RT, Gandhi T, Müller S, Reiter L, Hinterwirth H, Pechlaner R, Tsimikas S, Santer P, Willeit J, Kiechl S, Witztum JL, Sullivan A, Mayr M. PMID: 29237681.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    153. The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in Humans. Nucleic Acid Ther. 2018 02; 28(1):10-22. Crooke ST, Baker BF, Pham NC, Hughes SG, Kwoh TJ, Cai D, Tsimikas S, Geary RS, Bhanot S. PMID: 29185862; PMCID: PMC5790433.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    154. Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)Rx and IONIS-APO(a)-LRx antisense oligonucleotide clinical trials. J Clin Lipidol. 2018 Jan - Feb; 12(1):122-129.e2. Marcovina SM, Viney NJ, Hughes SG, Xia S, Witztum JL, Tsimikas S. PMID: 29174389.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    155. Threshold Effects of Circulating Angiopoietin-Like 3 Levels on Plasma Lipoproteins. J Clin Endocrinol Metab. 2017 09 01; 102(9):3340-3348. Fazio S, Minnier J, Shapiro MD, Tsimikas S, Tarugi P, Averna MR, Arca M, Tavori H. PMID: 28633452; PMCID: PMC5587068.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    156. Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up. Eur Heart J. 2017 Sep 01; 38(33):2547-2555. Hartikainen J, Hassinen I, Hedman A, Kivelä A, Saraste A, Knuuti J, Husso M, Mussalo H, Hedman M, Rissanen TT, Toivanen P, Heikura T, Witztum JL, Tsimikas S, Ylä-Herttuala S. PMID: 28903476; PMCID: PMC5837555.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCellsCTClinical Trials
    157. Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis. JACC Basic Transl Sci. 2017 Jun; 2(3):229-240. Torzewski M, Ravandi A, Yeang C, Edel A, Bhindi R, Kath S, Twardowski L, Schmid J, Yang X, Franke UFW, Witztum JL, Tsimikas S. PMID: 29147686; PMCID: PMC5685511.
      View in: PubMed   Mentions: 39  
    158. Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease: The Copenhagen General Population Study. Arterioscler Thromb Vasc Biol. 2017 08; 37(8):1570-1578. Kamstrup PR, Hung MY, Witztum JL, Tsimikas S, Nordestgaard BG. PMID: 28572160; PMCID: PMC5551411.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    159. Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides. N Engl J Med. 2017 07 20; 377(3):222-232. Graham MJ, Lee RG, Brandt TA, Tai LJ, Fu W, Peralta R, Yu R, Hurh E, Paz E, McEvoy BW, Baker BF, Pham NC, Digenio A, Hughes SG, Geary RS, Witztum JL, Crooke RM, Tsimikas S. PMID: 28538111.
      View in: PubMed   Mentions: 233     Fields:    Translation:HumansAnimalsCTClinical Trials
    160. Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol. 2017 06; 37(6):1206-1212. van Capelleveen JC, Bernelot Moens SJ, Yang X, Kastelein JJP, Wareham NJ, Zwinderman AH, Stroes ESG, Witztum JL, Hovingh GK, Khaw KT, Boekholdt SM, Tsimikas S. PMID: 28473441; PMCID: PMC5484077.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    161. Relationship of Autoantibodies to MDA-LDL and ApoB-Immune Complexes to Sex, Ethnicity, Subclinical Atherosclerosis, and Cardiovascular Events. Arterioscler Thromb Vasc Biol. 2017 06; 37(6):1213-1221. Prasad A, Clopton P, Ayers C, Khera A, de Lemos JA, Witztum JL, Tsimikas S. PMID: 28473443; PMCID: PMC5500201.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    162. Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis. Lancet Diabetes Endocrinol. 2017 07; 5(7):524-533. Saleheen D, Haycock PC, Zhao W, Rasheed A, Taleb A, Imran A, Abbas S, Majeed F, Akhtar S, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Mallick NH, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Frossard P, Tsimikas S, Witztum JL, Marcovina S, Sandhu M, Rader DJ, Danesh J. PMID: 28408323; PMCID: PMC5483508.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    163. Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgRKT to the List. Circ Res. 2017 03 31; 120(7):1050-1052. Yeang C, Gordts PL, Tsimikas S. PMID: 28360338; PMCID: PMC5470738.
      View in: PubMed   Mentions: 7     Fields:    
    164. Lipoprotein(a) Improves Cardiovascular Risk Prediction Based on Established Risk Algorithms. J Am Coll Cardiol. 2017 03 21; 69(11):1513-1515. Verbeek R, Sandhu MS, Hovingh GK, Sjouke B, Wareham NJ, Zwinderman AH, Kastelein JJP, Khaw KT, Tsimikas S, Boekholdt SM. PMID: 28302296.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    165. Lipoprotein(a) and incident type-2 diabetes: results from the prospective Bruneck study and a meta-analysis of published literature. Cardiovasc Diabetol. 2017 03 21; 16(1):38. Paige E, Masconi KL, Tsimikas S, Kronenberg F, Santer P, Weger S, Willeit J, Kiechl S, Willeit P. PMID: 28320383; PMCID: PMC5359972.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansPHPublic Health
    166. Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial. Atherosclerosis. 2017 05; 260:1-7. Capoulade R, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. PMID: 28319871.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    167. Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III. J Am Coll Cardiol. 2017 Feb 21; 69(7):789-800. Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum JL, Alexander VJ, Willeit J, Kiechl S, Mayr M. PMID: 28209220; PMCID: PMC5314136.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    168. Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis. J Biol Chem. 2017 03 31; 292(13):5378-5391. Lu J, Guo S, Xue X, Chen Q, Ge J, Zhuo Y, Zhong H, Chen B, Zhao M, Han W, Suzuki T, Zhu M, Xia L, Schneider C, Blackwell TS, Porter NA, Zheng L, Tsimikas S, Yin H. PMID: 28202546; PMCID: PMC5392682.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    169. A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies. J Am Coll Cardiol. 2017 Feb 14; 69(6):692-711. Tsimikas S. PMID: 28183512.
      View in: PubMed   Mentions: 336     Fields:    Translation:Humans
    170. Oxidized Phospholipids on Apolipoprotein B-100 and Recurrent Ischemic Events Following Stroke or Transient Ischemic Attack. J Am Coll Cardiol. 2017 Jan 17; 69(2):147-158. Byun YS, Yang X, Bao W, DeMicco D, Laskey R, Witztum JL, Tsimikas S, SPARCL Trial Investigators. PMID: 28081824.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    171. The Prevalence of Lipoprotein(a) Measurement and Degree of Elevation Among 2710 Patients With Calcific Aortic Valve Stenosis in an Academic Echocardiography Laboratory Setting. Angiology. 2017 Oct; 68(9):795-798. Wilkinson MJ, Ma GS, Yeang C, Ang L, Strachan M, DeMaria AN, Tsimikas S, Cotter B. PMID: 28068801.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    172. Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431 239 Patients. Arterioscler Thromb Vasc Biol. 2017 Mar; 37(3):580-588. Moriarty PM, Varvel SA, Gordts PL, McConnell JP, Tsimikas S. PMID: 28062489; PMCID: PMC5323356.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    173. LPA Gene, Ethnicity, and Cardiovascular Events. Circulation. 2017 Jan 17; 135(3):251-263. Lee SR, Prasad A, Choi YS, Xing C, Clopton P, Witztum JL, Tsimikas S. PMID: 27831500; PMCID: PMC5241172.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    174. Immune cell screening of a nanoparticle library improves atherosclerosis therapy. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6731-E6740. Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ. PMID: 27791119; PMCID: PMC5098679.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    175. Lipoprotein(a)-cholesterol levels estimated by vertical auto profile correlate poorly with Lp(a) mass in hyperlipidemic subjects: Implications for clinical practice interpretation of Lp(a)-mediated risk. J Clin Lipidol. 2016 Nov - Dec; 10(6):1389-1396. Yeang C, Clopton PC, Tsimikas S. PMID: 27919356; PMCID: PMC8545497.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    176. Prevalence of Elevated Lp(a) Mass Levels and Patient Thresholds in 532 359 Patients in the United States. Arterioscler Thromb Vasc Biol. 2016 11; 36(11):2239-2245. Varvel S, McConnell JP, Tsimikas S. PMID: 27659098.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    177. Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials. Lancet. 2016 11 05; 388(10057):2239-2253. Viney NJ, van Capelleveen JC, Geary RS, Xia S, Tami JA, Yu RZ, Marcovina SM, Hughes SG, Graham MJ, Crooke RM, Crooke ST, Witztum JL, Stroes ES, Tsimikas S. PMID: 27665230.
      View in: PubMed   Mentions: 255     Fields:    Translation:HumansCTClinical Trials
    178. Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans. Circulation. 2016 Aug 23; 134(8):611-24. van der Valk FM, Bekkering S, Kroon J, Yeang C, Van den Bossche J, van Buul JD, Ravandi A, Nederveen AJ, Verberne HJ, Scipione C, Nieuwdorp M, Joosten LA, Netea MG, Koschinsky ML, Witztum JL, Tsimikas S, Riksen NP, Stroes ES. PMID: 27496857; PMCID: PMC4995139.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansCellsCTClinical Trials
    179. The re-emergence of lipoprotein(a) in a broader clinical arena. Prog Cardiovasc Dis. 2016 Sep - Oct; 59(2):135-144. Tsimikas S. PMID: 27497506.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    180. Elevated Lp(a) and Abdominal Aortic Aneurysm. Angiology. 2017 02; 68(2):96-98. Alexandrou AT, Tsimikas S. PMID: 27207842.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    181. Lipoprotein(a) and oxidized phospholipids in calcific aortic valve stenosis. Curr Opin Cardiol. 2016 07; 31(4):440-50. Yeang C, Wilkinson MJ, Tsimikas S. PMID: 27205885; PMCID: PMC4956483.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    182. Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction. J Thromb Thrombolysis. 2016 Jul; 42(1):61-76. DeFilippis AP, Chernyavskiy I, Amraotkar AR, Trainor PJ, Kothari S, Ismail I, Hargis CW, Korley FK, Leibundgut G, Tsimikas S, Rai SN, Bhatnagar A. PMID: 26510751; PMCID: PMC5403145.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    183. Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease. J Intern Med. 2016 11; 280(5):509-517. Nsaibia MJ, Mahmut A, Boulanger MC, Arsenault BJ, Bouchareb R, Simard S, Witztum JL, Clavel MA, Pibarot P, Bossé Y, Tsimikas S, Mathieu P. PMID: 27237700.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    184. In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models. JACC Cardiovasc Imaging. 2016 08; 9(8):950-61. Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ. PMID: 27236528; PMCID: PMC5589956.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    185. Long-term mipomersen treatment is associated with a reduction in cardiovascular events in patients with familial hypercholesterolemia. J Clin Lipidol. 2016 Jul-Aug; 10(4):1011-1021. Duell PB, Santos RD, Kirwan BA, Witztum JL, Tsimikas S, Kastelein JJP. PMID: 27578134.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    186. Acute and long-term effect of percutaneous coronary intervention on serially-measured oxidative, inflammatory, and coagulation biomarkers in patients with stable angina. J Thromb Thrombolysis. 2016 May; 41(4):569-80. Leibundgut G, Lee JH, Strauss BH, Segev A, Tsimikas S. PMID: 26964999; PMCID: PMC4811750.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    187. PCSK9 Association With Lipoprotein(a). Circ Res. 2016 06 24; 119(1):29-35. Tavori H, Christian D, Minnier J, Plubell D, Shapiro MD, Yeang C, Giunzioni I, Croyal M, Duell PB, Lambert G, Tsimikas S, Fazio S. PMID: 27121620; PMCID: PMC4920709.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    188. The role of lipoprotein(a) in progression of renal disease: Causality or reverse causality? J Diabetes Complications. 2016 07; 30(5):755-7. Yeang C, Tsimikas S. PMID: 27118508.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    189. Lipoprotein(a): novel target and emergence of novel therapies to lower cardiovascular disease risk. Curr Opin Endocrinol Diabetes Obes. 2016 Apr; 23(2):157-64. Tsimikas S. PMID: 26825471; PMCID: PMC5061509.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    190. Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a). J Clin Lipidol. 2016 May-Jun; 10(3):594-603. Yeang C, Hung MY, Byun YS, Clopton P, Yang X, Witztum JL, Tsimikas S. PMID: 27206947.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    191. JCL Roundtable: Should we treat elevations in Lp(a)? J Clin Lipidol. 2016 Mar-Apr; 10(2):215-24. Brown WV, Moriarty PM, Remaley AT, Tsimikas S. PMID: 27055952.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    192. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4):682-91. Harmon DB, Srikakulapu P, Kaplan JL, Oldham SN, McSkimming C, Garmey JC, Perry HM, Kirby JL, Prohaska TA, Gonen A, Hallowell P, Schirmer B, Tsimikas S, Taylor AM, Witztum JL, McNamara CA. PMID: 26868208; PMCID: PMC4808436.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    193. Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results. J Lipid Res. 2016 Apr; 57(4):706-13. Yang X, Lee SR, Choi YS, Alexander VJ, Digenio A, Yang Q, Miller YI, Witztum JL, Tsimikas S. PMID: 26848137; PMCID: PMC4808774.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCTClinical Trials
    194. Experimental Animal Models Evaluating the Causal Role of Lipoprotein(a) in Atherosclerosis and Aortic Stenosis. Cardiovasc Drugs Ther. 2016 Feb; 30(1):75-85. Yeang C, Cotter B, Tsimikas S. PMID: 26780907.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    195. Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study. J Lipid Res. 2016 Apr; 57(4):697-705. Verbeek R, Boekholdt SM, Stoekenbroek RM, Hovingh GK, Witztum JL, Wareham NJ, Sandhu MS, Khaw KT, Tsimikas S. PMID: 26828068; PMCID: PMC4808778.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    196. Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans. J Lipid Res. 2016 Mar; 57(3):340-51. Graham MJ, Viney N, Crooke RM, Tsimikas S. PMID: 26538546; PMCID: PMC4767000.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    197. Mechanistic insights into Lp(a)-induced IL-8 expression: a role for oxidized phospholipid modification of apo(a). J Lipid Res. 2015 Dec; 56(12):2273-85. Scipione CA, Sayegh SE, Romagnuolo R, Tsimikas S, Marcovina SM, Boffa MB, Koschinsky ML. PMID: 26474593; PMCID: PMC4655984.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    198. Apolipoprotein C-III: From Pathophysiology to Pharmacology. Trends Pharmacol Sci. 2015 Oct; 36(10):675-687. Norata GD, Tsimikas S, Pirillo A, Catapano AL. PMID: 26435212.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    199. Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis. J Am Coll Cardiol. 2015 Sep 15; 66(11):1236-1246. Capoulade R, Chan KL, Yeang C, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Mahmut A, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. PMID: 26361154.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansCells
    200. Invasive Cardiologists Are Exposed to Greater Left Sided Cranial Radiation: The BRAIN Study (Brain Radiation Exposure and Attenuation During Invasive Cardiology Procedures). JACC Cardiovasc Interv. 2015 Aug 17; 8(9):1197-1206. Reeves RR, Ang L, Bahadorani J, Naghi J, Dominguez A, Palakodeti V, Tsimikas S, Patel MP, Mahmud E. PMID: 26292583.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansPHPublic Health
    201. Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study. Lancet. 2015 Oct 10; 386(10002):1472-83. Tsimikas S, Viney NJ, Hughes SG, Singleton W, Graham MJ, Baker BF, Burkey JL, Yang Q, Marcovina SM, Geary RS, Crooke RM, Witztum JL. PMID: 26210642.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansCellsCTClinical Trials
    202. B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis. Circ Res. 2015 Jul 17; 117(3):e28-39. Rosenfeld SM, Perry HM, Gonen A, Prohaska TA, Srikakulapu P, Grewal S, Das D, McSkimming C, Taylor AM, Tsimikas S, Bender TP, Witztum JL, McNamara CA. PMID: 26082558; PMCID: PMC4527334.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    203. Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-analysis of randomized controlled clinical trials in individuals without diabetes. Atherosclerosis. 2015 Aug; 241(2):409-18. Vallejo-Vaz AJ, Kondapally Seshasai SR, Kurogi K, Michishita I, Nozue T, Sugiyama S, Tsimikas S, Yoshida H, Ray KK. PMID: 26074315.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    204. 'LDL-C' = LDL-C + Lp(a)-C: implications of achieved ultra-low LDL-C levels in the proprotein convertase subtilisin/kexin type 9 era of potent LDL-C lowering. Curr Opin Lipidol. 2015 Jun; 26(3):169-78. Yeang C, Witztum JL, Tsimikas S. PMID: 25943842.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    205. HDL-C, ABCA1-mediated cholesterol efflux, and lipoprotein(a): insights into a potential novel physiologic role of lipoprotein(a). J Lipid Res. 2015 Jul; 56(7):1241-4. Yeang C, Tsimikas S. PMID: 26014961; PMCID: PMC4479328.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    206. Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study. Arterioscler Thromb Vasc Biol. 2015 Jul; 35(7):1704-11. Rao F, Schork AJ, Maihofer AX, Nievergelt CM, Marcovina SM, Miller ER, Witztum JL, O'Connor DT, Tsimikas S. PMID: 25953646; PMCID: PMC4483152.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    207. Retrieval of a detached transseptal sheath tip from a right pulmonary artery branch following catheter ablation. Catheter Cardiovasc Interv. 2015 Nov 15; 86(6):1131-5. Schricker AA, Feld GK, Tsimikas S. PMID: 25913843.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    208. Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial. J Am Coll Cardiol. 2015 Apr 07; 65(13):1286-1295. Byun YS, Lee JH, Arsenault BJ, Yang X, Bao W, DeMicco D, Laskey R, Witztum JL, Tsimikas S, TNT Trial Investigators. PMID: 25835440; PMCID: PMC4386070.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    209. Plasma Levels of Advanced Glycation End Products Are Related to the Clinical Presentation and Angiographic Severity of Symptomatic Lower Extremity Peripheral Arterial Disease. Int J Angiol. 2016 Mar; 25(1):44-53. Prasad A, Lane JR, Tsimikas S, Mahmud E, Khandrika S, Bekker P, Ilapakurti M, Nguyen D, Ravandi A, Israel T. PMID: 26900311; PMCID: PMC4758845.
      View in: PubMed   Mentions: 3  
    210. Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):689-99. Santos RD, Raal FJ, Catapano AL, Witztum JL, Steinhagen-Thiessen E, Tsimikas S. PMID: 25614280; PMCID: PMC4344404.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    211. Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc. 2015; 113:T5. Handa JT, Tagami M, Ebrahimi K, Leibundgut G, Janiak A, Witztum JL, Tsimikas S. PMID: 26538774; PMCID: PMC4601905.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    212. Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies. J Lipid Res. 2015 Feb; 56(2):440-8. Tsiantoulas D, Perkmann T, Afonyushkin T, Mangold A, Prohaska TA, Papac-Milicevic N, Millischer V, Bartel C, Hörkkö S, Boulanger CM, Tsimikas S, Fischer MB, Witztum JL, Lang IM, Binder CJ. PMID: 25525116; PMCID: PMC4306697.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    213. What is the ultimate test that lowering lipoprotein(a) is beneficial for cardiovascular disease and aortic stenosis? Curr Opin Lipidol. 2014 Dec; 25(6):423-30. Hung MY, Tsimikas S. PMID: 25340480.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    214. Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis. PLoS One. 2014; 9(11):e112483. Willeit P, Raschenberger J, Heydon EE, Tsimikas S, Haun M, Mayr A, Weger S, Witztum JL, Butterworth AS, Willeit J, Kronenberg F, Kiechl S. PMID: 25390655; PMCID: PMC4229188.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    215. Prevalence of coronary artery spasm after stent placement and its association with inflammation. Int J Cardiol. 2015 Jan 20; 179:252-5. Hung MJ, Hsu KH, Chang NC, Tsimikas S, Hung MY. PMID: 25464459.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    216. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1):229-36. Pechlaner R, Willeit P, Summerer M, Santer P, Egger G, Kronenberg F, Demetz E, Weiss G, Tsimikas S, Witztum JL, Willeit K, Iglseder B, Paulweber B, Kedenko L, Haun M, Meisinger C, Gieger C, Müller-Nurasyid M, Peters A, Willeit J, Kiechl S. PMID: 25359861; PMCID: PMC4317265.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    217. Imaging of oxidation-specific epitopes with targeted nanoparticles to detect high-risk atherosclerotic lesions: progress and future directions. J Cardiovasc Transl Res. 2014 Nov; 7(8):719-36. Briley-Saebo K, Yeang C, Witztum JL, Tsimikas S. PMID: 25297940; PMCID: PMC4233166.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    218. Lipoprotein apheresis and acute reduction of arterial inflammation: FDG-PET as an imaging biomarker of nonpharmacological effects on the vessel wall. J Am Coll Cardiol. 2014 Oct 07; 64(14):1427-9. Tsimikas S. PMID: 25277611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    219. Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study. J Am Coll Cardiol. 2014 Sep 02; 64(9):851-60. Willeit P, Kiechl S, Kronenberg F, Witztum JL, Santer P, Mayr M, Xu Q, Mayr A, Willeit J, Tsimikas S. PMID: 25169167.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    220. Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine. J Lipid Res. 2014 Oct; 55(10):2137-55. Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. PMID: 25143462; PMCID: PMC4174006.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    221. The severe hypercholesterolemia phenotype: clinical diagnosis, management, and emerging therapies. J Am Coll Cardiol. 2014 May 20; 63(19):1935-47. Sniderman AD, Tsimikas S, Fazio S. PMID: 24632267.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    222. Manganese G8 dendrimers targeted to oxidation-specific epitopes: in vivo MR imaging of atherosclerosis. J Magn Reson Imaging. 2015 Mar; 41(3):797-805. Nguyen TH, Bryant H, Shapsa A, Street H, Mani V, Fayad ZA, Frank JA, Tsimikas S, Briley-Saebo KC. PMID: 24610640; PMCID: PMC4160426.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    223. Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans. J Am Coll Cardiol. 2014 May 20; 63(19):1961-71. Ravandi A, Leibundgut G, Hung MY, Patel M, Hutchins PM, Murphy RC, Prasad A, Mahmud E, Miller YI, Dennis EA, Witztum JL, Tsimikas S. PMID: 24613321; PMCID: PMC4629781.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    224. Highlights of the year in JACC 2013. J Am Coll Cardiol. 2014 Feb 18; 63(6):570-602. DeMaria AN, Adler ED, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall JL, Hlatky MA, Lew WY, Lima JA, Mahmud E, Maisel AS, Narayan SM, Nissen SE, Sahn DJ, Tsimikas S. PMID: 24524815.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    225. Pro-inflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a). J Am Coll Cardiol. 2014 May 06; 63(17):1724-34. Tsimikas S, Duff GW, Berger PB, Rogus J, Huttner K, Clopton P, Brilakis E, Kornman KS, Witztum JL. PMID: 24530664; PMCID: PMC4008715.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    226. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. PLoS One. 2013; 8(12):e83145. Choi SH, Yin H, Ravandi A, Armando A, Dumlao D, Kim J, Almazan F, Taylor AM, McNamara CA, Tsimikas S, Dennis EA, Witztum JL, Miller YI. PMID: 24376657; PMCID: PMC3871536.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    227. New therapeutic targets for calcific aortic valve stenosis: the lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis. J Am Coll Cardiol. 2014 Feb 11; 63(5):478-80. Hung MY, Witztum JL, Tsimikas S. PMID: 24161316; PMCID: PMC5928500.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    228. Lipoprotein(a) for risk assessment in patients with established coronary artery disease. J Am Coll Cardiol. 2014 Feb 18; 63(6):520-7. O'Donoghue ML, Morrow DA, Tsimikas S, Sloan S, Ren AF, Hoffman EB, Desai NR, Solomon SD, Domanski M, Arai K, Chiuve SE, Cannon CP, Sacks FM, Sabatine MS. PMID: 24161323; PMCID: PMC3945105.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansPHPublic Health
    229. Helix-loop-helix factor inhibitor of differentiation 3 regulates interleukin-5 expression and B-1a B cell proliferation. Arterioscler Thromb Vasc Biol. 2013 Dec; 33(12):2771-9. Perry HM, Oldham SN, Fahl SP, Que X, Gonen A, Harmon DB, Tsimikas S, Witztum JL, Bender TP, McNamara CA. PMID: 24115031; PMCID: PMC4003558.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    230. The association between circulating lipoprotein(a) and type 2 diabetes: is it causal? Diabetes. 2014 Jan; 63(1):332-342. Ye Z, Haycock PC, Gurdasani D, Pomilla C, Boekholdt SM, Tsimikas S, Khaw KT, Wareham NJ, Sandhu MS, Forouhi NG. PMID: 24089516; PMCID: PMC4246060.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    231. Oxidation-specific epitopes as targets for biotheranostic applications in humans: biomarkers, molecular imaging and therapeutics. Curr Opin Lipidol. 2013 Oct; 24(5):426-37. Miller YI, Tsimikas S. PMID: 23995232; PMCID: PMC4085330.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    232. Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol. 2013 Nov 19; 62(21):1966-1976. Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EPA, Li M, Leusink M, Trompet S, Verschuren JJW, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, van 't Hooft F, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Mateo Leach I, Breitling LP, Brenner H, Thiery J, Dallmeier D, Franco-Cereceda A, Boer JMA, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day INM, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der Zee AH, Khaw KT, Keating BJ, van der Harst P, Price JF, Mehta SR, Yusuf S, Witteman JCM, Franco OH, Jukema JW, de Knijff P, Tybjaerg-Hansen A, Rader DJ, Farrall M, Samani NJ, Kivimaki M, Fox KAA, Humphries SE, Anderson JL, Boekholdt SM, Palmer TM, Eriksson P, Paré G, Hingorani AD, Sabatine MS, Mallat Z, Casas JP, Talmud PJ. PMID: 23916927; PMCID: PMC3826105.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    233. Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res. 2013 Oct; 54(10):2815-30. Leibundgut G, Scipione C, Yin H, Schneider M, Boffa MB, Green S, Yang X, Dennis E, Witztum JL, Koschinsky ML, Tsimikas S. PMID: 23828779; PMCID: PMC3770094.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    234. Tracking oxidatively stressed cardiac stem cells with molecular imaging: "insights" into fate, viability, and function. JACC Cardiovasc Imaging. 2013 Jul; 6(7):803-5. Tsimikas S. PMID: 23845575.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    235. IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitope. PLoS One. 2013; 8(6):e65203. Que X, Widhopf GF, Amir S, Hartvigsen K, Hansen LF, Woelkers D, Tsimikas S, Binder CJ, Kipps TJ, Witztum JL. PMID: 23840319; PMCID: PMC3688726.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    236. Statin therapy and secretory phospholipase A₂ in children with heterozygous familial hypercholesterolemia. Atherosclerosis. 2013 Aug; 229(2):404-7. Braamskamp MJ, Tsimikas S, Wiegman A, Kastelein JJ, Hutten BA. PMID: 23880195.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    237. MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res. 2013 Jul; 54(7):1877-83. Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI. PMID: 23667177; PMCID: PMC3679389.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    238. Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis. Curr Opin Pharmacol. 2013 Apr; 13(2):168-79. Leibundgut G, Witztum JL, Tsimikas S. PMID: 23541680; PMCID: PMC3844667.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    239. Oxidation-specific biomarkers and risk of peripheral artery disease. J Am Coll Cardiol. 2013 May 28; 61(21):2169-79. Bertoia ML, Pai JK, Lee JH, Taleb A, Joosten MM, Mittleman MA, Yang X, Witztum JL, Rimm EB, Tsimikas S, Mukamal KJ. PMID: 23541965; PMCID: PMC3756816.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    240. Highlights of the year in JACC 2012. J Am Coll Cardiol. 2013 Jan 22; 61(3):357-85. DeMaria AN, Bax JJ, Feld GK, Greenberg BH, Hall JL, Hlatky MA, Lew WY, Lima JA, Mahmud E, Maisel AS, Narayan SM, Nissen SE, Sahn DJ, Tsimikas S. PMID: 23328613; PMCID: PMC3760511.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    241. Adaptive immunity in atherogenesis: new insights and therapeutic approaches. J Clin Invest. 2013 Jan; 123(1):27-36. Lichtman AH, Binder CJ, Tsimikas S, Witztum JL. PMID: 23281407; PMCID: PMC3533280.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    242. Emerging therapeutic agents to lower lipoprotein (a) levels. Curr Opin Lipidol. 2012 Dec; 23(6):560-8. Kolski B, Tsimikas S. PMID: 23041907.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    243. Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia. Atherosclerosis. 2013 Jan; 226(1):161-4. Yoshida H, Shoda T, Yanai H, Ikewaki K, Kurata H, Ito K, Furutani N, Tada N, Witztum JL, Tsimikas S. PMID: 23174369.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    244. Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events. J Am Coll Cardiol. 2012 Nov 20; 60(21):2218-29. Tsimikas S, Willeit P, Willeit J, Santer P, Mayr M, Xu Q, Mayr A, Witztum JL, Kiechl S. PMID: 23122790.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    245. Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12):3058-65. Gurdasani D, Sjouke B, Tsimikas S, Hovingh GK, Luben RN, Wainwright NW, Pomilla C, Wareham NJ, Khaw KT, Boekholdt SM, Sandhu MS. PMID: 23065826; PMCID: PMC4210842.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    246. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52. Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. PMID: 23021221; PMCID: PMC3464914.
      View in: PubMed   Mentions: 301     Fields:    Translation:AnimalsCells
    247. Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations. Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12):3066-75. Holleboom AG, Daniil G, Fu X, Zhang R, Hovingh GK, Schimmel AW, Kastelein JJ, Stroes ES, Witztum JL, Hutten BA, Tsimikas S, Hazen SL, Chroni A, Kuivenhoven JA. PMID: 23023370; PMCID: PMC3610418.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    248. Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions. J Lipid Res. 2012 Dec; 53(12):2773-90. van Dijk RA, Kolodgie F, Ravandi A, Leibundgut G, Hu PP, Prasad A, Mahmud E, Dennis E, Curtiss LK, Witztum JL, Wasserman BA, Otsuka F, Virmani R, Tsimikas S. PMID: 22969153; PMCID: PMC3494262.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    249. Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol. 2012 Aug 21; 60(8):716-21. Tsimikas S, Hall JL. PMID: 22898069.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimals
    250. Regression of inflammation in atherosclerosis by the LXR agonist R211945: a noninvasive assessment and comparison with atorvastatin. JACC Cardiovasc Imaging. 2012 Aug; 5(8):819-28. Vucic E, Calcagno C, Dickson SD, Rudd JH, Hayashi K, Bucerius J, Moshier E, Mounessa JS, Roytman M, Moon MJ, Lin J, Ramachandran S, Tanimoto T, Brown K, Kotsuma M, Tsimikas S, Fisher EA, Nicolay K, Fuster V, Fayad ZA. PMID: 22897996; PMCID: PMC3600612.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    251. Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis. J Am Coll Cardiol. 2012 Jul 10; 60(2):112-9. Purushothaman KR, Purushothaman M, Levy AP, Lento PA, Evrard S, Kovacic JC, Briley-Saebo KC, Tsimikas S, Witztum JL, Krishnan P, Kini A, Fayad ZA, Fuster V, Sharma SK, Moreno PR. PMID: 22766337.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    252. Advanced glycation end products and diabetic cardiovascular disease. Cardiol Rev. 2012 Jul-Aug; 20(4):177-83. Prasad A, Bekker P, Tsimikas S. PMID: 22314141.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    253. Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia. J Lipid Res. 2012 Aug; 53(8):1670-8. Arai K, Orsoni A, Mallat Z, Tedgui A, Witztum JL, Bruckert E, Tselepis AD, Chapman MJ, Tsimikas S. PMID: 22628616; PMCID: PMC3540845.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    254. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb). 2012 Jun; 4(6):595-605. Olson ES, Whitney MA, Friedman B, Aguilera TA, Crisp JL, Baik FM, Jiang T, Baird SM, Tsimikas S, Tsien RY, Nguyen QT. PMID: 22534729; PMCID: PMC3689578.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    255. Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction. J Am Coll Cardiol. 2012 Apr 17; 59(16):1426-37. Leibundgut G, Arai K, Orsoni A, Yin H, Scipione C, Miller ER, Koschinsky ML, Chapman MJ, Witztum JL, Tsimikas S. PMID: 22497821; PMCID: PMC3333481.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    256. Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease. J Lipid Res. 2012 Jul; 53(7):1316-26. Amir S, Hartvigsen K, Gonen A, Leibundgut G, Que X, Jensen-Jarolim E, Wagner O, Tsimikas S, Witztum JL, Binder CJ. PMID: 22508944; PMCID: PMC3371243.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    257. Lipoprotein oxidation biomarkers for cardiovascular risk: what does the future hold? Expert Rev Cardiovasc Ther. 2012 Apr; 10(4):399-402. Taleb A, Tsimikas S. PMID: 22458571.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    258. The clinical emergence of optical coherence tomography: defining a role in intravascular imaging. J Am Coll Cardiol. 2012 Mar 20; 59(12):1090-2. Tsimikas S, DeMaria AN. PMID: 22421302.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    259. Effect of an oral astaxanthin prodrug (CDX-085) on lipoprotein levels and progression of atherosclerosis in LDLR(-/-) and ApoE(-/-) mice. Atherosclerosis. 2012 May; 222(1):99-105. Ryu SK, King TJ, Fujioka K, Pattison J, Pashkow FJ, Tsimikas S. PMID: 22406426.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    260. In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes. J Am Coll Cardiol. 2012 Feb 07; 59(6):616-26. Briley-Saebo KC, Nguyen TH, Saeboe AM, Cho YS, Ryu SK, Volkova ER, Volkava E, Dickson S, Leibundgut G, Wiesner P, Weisner P, Green S, Casanada F, Miller YI, Shaw W, Witztum JL, Fayad ZA, Tsimikas S. PMID: 22300697; PMCID: PMC3333483.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    261. Highlights of the Year in JACC 2011. J Am Coll Cardiol. 2012 Jan 31; 59(5):503-37. Demaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 22281255.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    262. Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes. Circulation. 2012 Feb 14; 125(6):757-66. Ryu SK, Mallat Z, Benessiano J, Tedgui A, Olsson AG, Bao W, Schwartz GG, Tsimikas S, Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering (MIRACL) Trial Investigators. PMID: 22230483.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    263. In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish. J Clin Invest. 2011 Dec; 121(12):4861-9. Fang L, Green SR, Baek JS, Lee SH, Ellett F, Deer E, Lieschke GJ, Witztum JL, Tsimikas S, Miller YI. PMID: 22105168; PMCID: PMC3225997.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    264. The role of oxidized phospholipids, lipoprotein (a) and biomarkers of oxidized lipoproteins in chronically occluded coronary arteries in sudden cardiac death and following successful percutaneous revascularization. Cardiovasc Revasc Med. 2012 Jan-Feb; 13(1):11-9. Fefer P, Tsimikas S, Segev A, Sparkes J, Otsuka F, Otsuma F, Kolodgie F, Virmani R, Juliano J, Charron T, Strauss BH. PMID: 22079685.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    265. B-cell aortic homing and atheroprotection depend on Id3. Circ Res. 2012 Jan 06; 110(1):e1-12. Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, McNamara CA. PMID: 22034493; PMCID: PMC3253259.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    266. Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression. J Am Coll Cardiol. 2011 Oct 11; 58(16):1715-27. Tsimikas S, Miyanohara A, Hartvigsen K, Merki E, Shaw PX, Chou MY, Pattison J, Torzewski M, Sollors J, Friedmann T, Lai NC, Hammond HK, Getz GS, Reardon CA, Li AC, Banka CL, Witztum JL. PMID: 21982317; PMCID: PMC3230644.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    267. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011 Oct 05; 478(7367):76-81. Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. PMID: 21979047; PMCID: PMC4826616.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimalsCells
    268. Oxidized phospholipids on apoB-100-containing lipoproteins: a biomarker predicting cardiovascular disease and cardiovascular events. Biomark Med. 2011 Oct; 5(5):673-94. Taleb A, Witztum JL, Tsimikas S. PMID: 22003918; PMCID: PMC3230643.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    269. Pioglitazone modulates vascular inflammation in atherosclerotic rabbits noninvasive assessment with FDG-PET-CT and dynamic contrast-enhanced MR imaging. JACC Cardiovasc Imaging. 2011 Oct; 4(10):1100-9. Vucic E, Dickson SD, Calcagno C, Rudd JH, Moshier E, Hayashi K, Mounessa JS, Roytman M, Moon MJ, Lin J, Tsimikas S, Fisher EA, Nicolay K, Fuster V, Fayad ZA. PMID: 21999870; PMCID: PMC3253377.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    270. Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists. J Clin Lipidol. 2011 Sep-Oct; 5(5):338-67. Davidson MH, Ballantyne CM, Jacobson TA, Bittner VA, Braun LT, Brown AS, Brown WV, Cromwell WC, Goldberg RB, McKenney JM, Remaley AT, Sniderman AD, Toth PP, Tsimikas S, Ziajka PE, Maki KC, Dicklin MR. PMID: 21981835.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    271. OxPL/apoB, lipoprotein(a) and OxLDL biomarkers and cardiovascular disease in chronic hemodialysis patients. J Nephrol. 2011 Sep-Oct; 24(5):581-8. Bossola M, Tazza L, Luciani G, Tortorelli A, Tsimikas S. PMID: 21404224.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    272. Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. J Lipid Res. 2011 Oct; 52(10):1829-36. Ravandi A, Boekholdt SM, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Tsimikas S. PMID: 21821825; PMCID: PMC3173004.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    273. Renal artery plaque composition is associated with changes in renal frame count following renal artery stenting. J Invasive Cardiol. 2011 Jun; 23(6):227-31. Prasad A, Ilapakurti M, Hu P, Zafar N, Palakodeti V, Tsimikas S, Mahmud E. PMID: 21646647.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    274. Successful treatment of in-stent restenosis of a covered stent graft with a paclitaxel-eluting stent. J Cardiol Cases. 2011 Aug; 4(1):e13-e15. Thani KB, Bennett WE, Ravandi A, Tsimikas S. PMID: 30532863; PMCID: PMC6265220.
      View in: PubMed   Mentions:
    275. Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice. J Am Coll Cardiol. 2011 Apr 12; 57(15):1611-21. Merki E, Graham M, Taleb A, Leibundgut G, Yang X, Miller ER, Fu W, Mullick AE, Lee R, Willeit P, Crooke RM, Witztum JL, Tsimikas S. PMID: 21474042.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    276. Highlights of the year in JACC 2010. J Am Coll Cardiol. 2011 Jan 25; 57(4):480-514. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 21251590.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    277. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res. 2011 Jan 21; 108(2):235-48. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. PMID: 21252151; PMCID: PMC3075542.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansAnimalsCells
    278. Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease. Curr Pharm Des. 2011; 17(1):27-37. Tsimikas S, Miller YI. PMID: 21226665.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    279. Imaging of Oxidation-Specific Epitopes in Atherosclerosis and Macrophage-Rich Vulnerable Plaques. Curr Cardiovasc Imaging Rep. 2011 Feb; 4(1):4-16. Briley-Saebo KC, Cho YS, Tsimikas S. PMID: 21297859; PMCID: PMC3018294.
      View in: PubMed   Mentions: 12  
    280. Targeted iron oxide particles for in vivo magnetic resonance detection of atherosclerotic lesions with antibodies directed to oxidation-specific epitopes. J Am Coll Cardiol. 2011 Jan 18; 57(3):337-47. Briley-Saebo KC, Cho YS, Shaw PX, Ryu SK, Mani V, Dickson S, Izadmehr E, Green S, Fayad ZA, Tsimikas S. PMID: 21106318; PMCID: PMC3095034.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    281. Lipoprotein-associated phospholipase A2 mass and activity in children with heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Clin Lipidol. 2011 Jan-Feb; 5(1):50-6. Ryu SK, Hutten BA, Vissers MN, Wiegman A, Kastelein JJ, Tsimikas S. PMID: 21262507.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    282. Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab. 2010 Nov 03; 12(5):467-82. Seimon TA, Nadolski MJ, Liao X, Magallon J, Nguyen M, Feric NT, Koschinsky ML, Harkewicz R, Witztum JL, Tsimikas S, Golenbock D, Moore KJ, Tabas I. PMID: 21035758; PMCID: PMC2991104.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    283. Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol. 2010 Sep 14; 56(12):946-55. Tsimikas S, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Sandhu MS, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Boekholdt SM. PMID: 20828647.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    284. Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet. J Lipid Res. 2010 Nov; 51(11):3324-30. Faghihnia N, Tsimikas S, Miller ER, Witztum JL, Krauss RM. PMID: 20713651; PMCID: PMC2952573.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    285. Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation. J Biol Chem. 2010 Oct 15; 285(42):32343-51. Fang L, Harkewicz R, Hartvigsen K, Wiesner P, Choi SH, Almazan F, Pattison J, Deer E, Sayaphupha T, Dennis EA, Witztum JL, Tsimikas S, Miller YI. PMID: 20710028; PMCID: PMC2952235.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    286. Lipoprotein(a) accelerates atherosclerosis in uremic mice. J Lipid Res. 2010 Oct; 51(10):2967-75. Pedersen TX, McCormick SP, Tsimikas S, Bro S, Nielsen LB. PMID: 20584868; PMCID: PMC2936745.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    287. Clinical Trial Report: The Presence and Rupture of Vulnerable Plaques in the Peripheral Circulation. Curr Cardiovasc Imaging Rep. 2010 Aug; 3(4):187-189. Prasad A, Tsimikas S. PMID: 20676192; PMCID: PMC2895890.
      View in: PubMed   Mentions: 1  
    288. Post-thienopyridine platelet response, cardiovascular outcomes, and personalized therapy: En attendant Godot. JACC Cardiovasc Interv. 2010 Jun; 3(6):657-9. Tsimikas S, Leibundgut G. PMID: 20630459.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    289. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium. Am J Cardiol. 2010 Feb 15; 105(4):459-66. Ahmadi N, Tsimikas S, Hajsadeghi F, Saeed A, Nabavi V, Bevinal MA, Kadakia J, Flores F, Ebrahimi R, Budoff MJ. PMID: 20152239.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    290. Highlights of the Year in JACC 2009. J Am Coll Cardiol. 2010 Jan 26; 55(4):380-407. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 20117446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    291. Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis. Subcell Biochem. 2010; 51:229-51. Miller YI, Choi SH, Fang L, Tsimikas S. PMID: 20213546.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    292. The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles. Atherosclerosis. 2010 Apr; 209(2):498-503. Arai K, Luke MM, Koschinsky ML, Miller ER, Pullinger CR, Witztum JL, Kane JP, Tsimikas S. PMID: 19880117.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    293. High-dose statins prior to percutaneous coronary intervention: a paradigm shift to influence clinical outcomes in the cardiac catheterization laboratory. J Am Coll Cardiol. 2009 Dec 01; 54(23):2164-6. Tsimikas S. PMID: 19775848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    294. Spontaneous recanalization of a completely occluded saphenous vein graft two months following acute myocardial infarction with persistent one year patency. J Thromb Thrombolysis. 2009 Jul; 28(1):101-5. Hu PP, Peterson KL, Tsimikas S. PMID: 19396586; PMCID: PMC2694324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    295. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial. Prev Med. 2009 Aug-Sep; 49(2-3):101-7. Budoff MJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S. PMID: 19573556.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    296. Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial. J Am Coll Cardiol. 2009 Jun 09; 53(23):2186-96. Fraley AE, Schwartz GG, Olsson AG, Kinlay S, Szarek M, Rifai N, Libby P, Ganz P, Witztum JL, Tsimikas S, MIRACL Study Investigators. PMID: 19497447.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    297. Estrogen-eluting stents. J Cardiovasc Transl Res. 2009 Sep; 2(3):240-4. Ryu SK, Mahmud E, Tsimikas S. PMID: 19654888; PMCID: PMC2719737.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    298. Relationship of oxidized phospholipids on apolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study. Circulation. 2009 Apr 07; 119(13):1711-9. Tsimikas S, Clopton P, Brilakis ES, Marcovina SM, Khera A, Miller ER, de Lemos JA, Witztum JL. PMID: 19307470; PMCID: PMC2782388.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    299. Molecular imaging of matrix metalloproteinase expression in atherosclerotic plaques of mice deficient in apolipoprotein e or low-density-lipoprotein receptor. J Nucl Med. 2009 Apr; 50(4):612-7. Ohshima S, Petrov A, Fujimoto S, Zhou J, Azure M, Edwards DS, Murohara T, Narula N, Tsimikas S, Narula J. PMID: 19289429.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    300. Highlights of the Year in JACC 2008. J Am Coll Cardiol. 2009 Jan 27; 53(4):373-98. DeMaria AN, Ben-Yehuda O, Bax JJ, Feld GK, Greenberg BH, Lew WY, Lima JA, Maisel AS, Narayan SM, Sahn DJ, Tsimikas S. PMID: 19161890.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    301. The role of innate immunity in atherogenesis. J Lipid Res. 2009 Apr; 50 Suppl:S388-93. Hartvigsen K, Chou MY, Hansen LF, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. PMID: 19106070; PMCID: PMC2674727.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    302. The role of oxidized phospholipids in atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S207-12. Berliner JA, Leitinger N, Tsimikas S. PMID: 19059906; PMCID: PMC2674746.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    303. Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study. Eur Heart J. 2009 Jan; 30(1):107-15. Tsimikas S, Willeit J, Knoflach M, Mayr M, Egger G, Notdurfter M, Witztum JL, Wiedermann CJ, Xu Q, Kiechl S. PMID: 19019993.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    304. Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population. Atherosclerosis. 2009 Jul; 205(1):261-5. Kiechl S, Lee T, Santer P, Thompson G, Tsimikas S, Egger G, Holt DW, Willeit J, Xu Q, Mayr M. PMID: 19100547.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    305. Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel. J Am Coll Cardiol. 2008 Sep 23; 52(13):1052-9. Ang L, Palakodeti V, Khalid A, Tsimikas S, Idrees Z, Tran P, Clopton P, Zafar N, Bromberg-Marin G, Keramati S, Mahmud E. PMID: 18848137.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    306. The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity. Curr Opin Lipidol. 2008 Aug; 19(4):369-77. Tsimikas S, Witztum JL. PMID: 18607184.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    307. Candidate biomarkers for the detection of coronary plaque destabilization and rupture. Curr Atheroscler Rep. 2008 Aug; 10(4):309-17. Prasad A, Tsimikas S. PMID: 18618976.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    308. Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice. Circulation. 2008 Aug 12; 118(7):743-53. Merki E, Graham MJ, Mullick AE, Miller ER, Crooke RM, Pitas RE, Witztum JL, Tsimikas S. PMID: 18663084.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    309. A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res. 2008 Oct; 49(10):2230-9. Bergmark C, Dewan A, Orsoni A, Merki E, Miller ER, Shin MJ, Binder CJ, Hörkkö S, Krauss RM, Chapman MJ, Witztum JL, Tsimikas S. PMID: 18594118.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansCells
    310. Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study. J Am Coll Cardiol. 2008 Jul 01; 52(1):24-32. Choi SH, Chae A, Miller E, Messig M, Ntanios F, DeMaria AN, Nissen SE, Witztum JL, Tsimikas S. PMID: 18582631.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    311. The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents. J Am Coll Cardiol. 2008 Jun 10; 51(23):2228-9. Choi SH, Prasad A, Tsimikas S. PMID: 18534268.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    312. Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes. Circulation. 2008 Jun 24; 117(25):3206-15. Briley-Saebo KC, Shaw PX, Mulder WJ, Choi SH, Vucic E, Aguinaldo JG, Witztum JL, Fuster V, Tsimikas S, Fayad ZA. PMID: 18541740; PMCID: PMC4492476.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    313. Renal frame count and renal blush grade: quantitative measures that predict the success of renal stenting in hypertensive patients with renal artery stenosis. JACC Cardiovasc Interv. 2008 Jun; 1(3):286-92. Mahmud E, Smith TW, Palakodeti V, Zaidi O, Ang L, Mitchell CR, Zafar N, Bromberg-Marin G, Keramati S, Tsimikas S. PMID: 19463314.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    314. In vivo markers of oxidative stress and therapeutic interventions. Am J Cardiol. 2008 May 22; 101(10A):34D-42D. Tsimikas S. PMID: 18474272.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    315. Recent advances in hemodynamics: noncoronary applications of a pressure sensor angioplasty guidewire. Catheter Cardiovasc Interv. 2008 May 01; 71(6):748-58. Cavendish JJ, Carter LI, Tsimikas S. PMID: 18324696.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    316. The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. J Am Coll Cardiol. 2008 Apr 29; 51(17):1653-62. Ky B, Burke A, Tsimikas S, Wolfe ML, Tadesse MG, Szapary PO, Witztum JL, FitzGerald GA, Rader DJ. PMID: 18436117.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCTClinical Trials
    317. Highlights of the year in JACC 2007. J Am Coll Cardiol. 2008 Jan 29; 51(4):490-512. DeMaria AN, Bax JJ, Ben-Yehuda O, Clopton P, Feld GK, Ginsburg GS, Greenberg BH, Knoke JD, Lew WY, Lima JA, Maisel AS, Narayan SM, Narula J, Sahn DJ, Tsimikas S. PMID: 18222362.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    318. Oxidized low-density lipoprotein biomarkers in patients with end-stage renal failure: acute effects of hemodialysis. Blood Purif. 2007; 25(5-6):457-65. Bossola M, Tazza L, Merki E, Giungi S, Luciani G, Miller ER, Lin EB, Tortorelli A, Tsimikas S. PMID: 18075247.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    319. Antibodies to oxidized low density lipoprotein: epidemiological studies and potential clinical applications in cardiovascular disease. Minerva Cardioangiol. 2007 Dec; 55(6):821-37. Gounopoulos P, Merki E, Hansen LF, Choi SH, Tsimikas S. PMID: 18091649.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    320. New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease. Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2094-9. Tsimikas S, Tsironis LD, Tselepis AD. PMID: 17626905.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    321. Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1788-95. Kiechl S, Willeit J, Mayr M, Viehweider B, Oberhollenzer M, Kronenberg F, Wiedermann CJ, Oberthaler S, Xu Q, Witztum JL, Tsimikas S. PMID: 17541022.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansPHPublic Health
    322. Elevated plasma fibrinogen level predicts suboptimal response to therapy with both single- and double-bolus eptifibatide during percutaneous coronary intervention. J Am Coll Cardiol. 2007 Jun 05; 49(22):2163-71. Mahmud E, Cavendish JJ, Tsimikas S, Ang L, Nguyen C, Bromberg-Marin G, Schnyder G, Keramati S, Palakodeti V, Penny WF, DeMaria AN. PMID: 17543636.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    323. Spontaneous multivessel coronary vasospasm leading to cardiogenic shock. J Invasive Cardiol. 2007 Apr; 19(4):E85-8. Bromberg-Marin G, Mahmud E, Tsimikas S. PMID: 17404410.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    324. Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus. Catheter Cardiovasc Interv. 2007 Feb 15; 69(3):362-8. Bromberg-Marin G, Tsimikas S, Mahmud E. PMID: 17200960.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    325. Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):850-7. Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ. PMID: 17255533.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    326. Emerging approaches for imaging vulnerable plaques in patients. Curr Opin Biotechnol. 2007 Feb; 18(1):73-82. Choi SH, Chae A, Chen CH, Merki E, Shaw PX, Tsimikas S. PMID: 17234398.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    327. Highlights of the Year in JACC 2006. J Am Coll Cardiol. 2007 Jan 30; 49(4):509-27. DeMaria AN, Ben-Yehuda O, Feld GK, Ginsburg GS, Greenberg BH, Lew WY, Lima JA, Maisel AS, Narula J, Sahn DJ, Tsimikas S. PMID: 17258099.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    328. Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events. J Lipid Res. 2007 Feb; 48(2):425-33. Tsimikas S, Brilakis ES, Lennon RJ, Miller ER, Witztum JL, McConnell JP, Kornman KS, Berger PB. PMID: 17093289.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    329. Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):175-81. Tsimikas S, Aikawa M, Miller FJ, Miller ER, Torzewski M, Lentz SR, Bergmark C, Heistad DD, Libby P, Witztum JL. PMID: 17082490.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    330. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease. Curr Opin Lipidol. 2006 Oct; 17(5):502-9. Fraley AE, Tsimikas S. PMID: 16960498.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    331. Oxidative biomarkers in the diagnosis and prognosis of cardiovascular disease. Am J Cardiol. 2006 Dec 04; 98(11A):9P-17P. Tsimikas S. PMID: 17126679.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    332. Measures of oxidative stress. Clin Lab Med. 2006 Sep; 26(3):571-90, v-vi. Tsimikas S. PMID: 16938585.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    333. Noninvasive imaging of atherosclerotic lesions in apolipoprotein E-deficient and low-density-lipoprotein receptor-deficient mice with annexin A5. J Nucl Med. 2006 Sep; 47(9):1497-505. Isobe S, Tsimikas S, Zhou J, Fujimoto S, Sarai M, Branks MJ, Fujimoto A, Hofstra L, Reutelingsperger CP, Murohara T, Virmani R, Kolodgie FD, Narula N, Petrov A, Narula J. PMID: 16954559.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    334. Statin-associated pleiotropy: possible beneficial effects beyond cholesterol reduction. Pharmacotherapy. 2006 Jul; 26(7 Pt 2):85S-97S; discussion 98S-101S; quiz 106S-108S. Ito MK, Talbert RL, Tsimikas S. PMID: 16803418.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    335. Successful utilization of a novel aspiration thrombectomy catheter (Pronto) for the treatment of patients with stent thrombosis. Catheter Cardiovasc Interv. 2006 Jun; 67(6):894-9. Siddiqui DS, Choi CJ, Tsimikas S, Mahmud E. PMID: 16649245.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    336. Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study. J Am Coll Cardiol. 2006 Jun 20; 47(12):2436-43. Mayr M, Kiechl S, Tsimikas S, Miller E, Sheldon J, Willeit J, Witztum JL, Xu Q. PMID: 16781371.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    337. Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study. J Am Coll Cardiol. 2006 Jun 06; 47(11):2219-28. Tsimikas S, Kiechl S, Willeit J, Mayr M, Miller ER, Kronenberg F, Xu Q, Bergmark C, Weger S, Oberhollenzer F, Witztum JL. PMID: 16750687.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    338. Imaging vulnerable plaque by ultrasound. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C32-9. DeMaria AN, Narula J, Mahmud E, Tsimikas S. PMID: 16631508.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    339. C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C19-31. Tsimikas S, Willerson JT, Ridker PM. PMID: 16631506.
      View in: PubMed   Mentions: 94     Fields:    Translation:Humans
    340. Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Am Coll Cardiol. 2006 May 02; 47(9):1803-10. Rodenburg J, Vissers MN, Wiegman A, Miller ER, Ridker PM, Witztum JL, Kastelein JJ, Tsimikas S. PMID: 16682304.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    341. Drug-eluting stents and late adverse clinical outcomes lessons learned, lessons awaited. J Am Coll Cardiol. 2006 May 16; 47(10):2112-5. Tsimikas S. PMID: 16697332.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    342. Fibromuscular dysplasia of renal arteries: percutaneous revascularization based on hemodynamic assessment with a pressure measurement guidewire. Catheter Cardiovasc Interv. 2006 Mar; 67(3):434-7. Mahmud E, Brocato M, Palakodeti V, Tsimikas S. PMID: 16475187.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    343. Oxidized low-density lipoprotein biomarkers in atherosclerosis. Curr Atheroscler Rep. 2006 Jan; 8(1):55-61. Tsimikas S. PMID: 16455015.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    344. Highlights of the Year in JACC 2005. J Am Coll Cardiol. 2006 Jan 03; 47(1):184-202. Demaria AN, Ben-Yehuda O, Berman D, Feld GK, Ginsberg J, Greenberg BH, Lew WY, Sahn D, Tsimikas S. PMID: 16386685.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    345. Rapid progression of common femoral artery stenosis leading to development of ischemic foot ulcer following repeated ipsilateral arterial access. Catheter Cardiovasc Interv. 2005 Dec; 66(4):487-90. Guillinta P, Waltman T, Tsimikas S. PMID: 16273576.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    346. Treatment of ischemic stroke complicating cardiac catheterization with systemic thrombolytic therapy. Catheter Cardiovasc Interv. 2005 Nov; 66(3):364-8. Serry R, Tsimikas S, Imbesi SG, Mahmud E. PMID: 16208693.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    347. Relationship of a comprehensive panel of plasma oxidized low-density lipoprotein markers to angiographic restenosis in patients undergoing percutaneous coronary intervention for stable angina. Am Heart J. 2005 Nov; 150(5):1007-14. Segev A, Strauss BH, Witztum JL, Lau HK, Tsimikas S. PMID: 16290986.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    348. Catheter-induced vasospasm of both the right external iliac and right coronary arteries during coronary angiography. Int J Cardiovasc Imaging. 2005 Oct; 21(5):481-5. Shortal BP, Mahmud E, Tsimikas S. PMID: 16175434.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    349. Consequences of cholesteryl ester transfer protein inhibition in patients with familial hypoalphalipoproteinemia. Arterioscler Thromb Vasc Biol. 2005 Sep; 25(9):e133-4. Bisoendial RJ, Hovingh GK, El Harchaoui K, Levels JH, Tsimikas S, Pu K, Zwinderman AE, Kuivenhoven JA, Kastelein JJ, Stroes ES. PMID: 16127020.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    350. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med. 2005 Jul 07; 353(1):46-57. Tsimikas S, Brilakis ES, Miller ER, McConnell JP, Lennon RJ, Kornman KS, Witztum JL, Berger PB. PMID: 16000355.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansCells
    351. Expanded applications of rotational atherectomy in contemporary coronary and peripheral interventional practice. J Invasive Cardiol. 2005 Apr; 17(4):207-10. Mahmud E, Keramati S, Salami A, Palakodeti V, Tsimikas S. PMID: 15831974.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    352. Transcatheter closure of patent foramen ovale for migraine prophylaxis: hope or hype? J Am Coll Cardiol. 2005 Feb 15; 45(4):496-8. Tsimikas S. PMID: 15708693.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    353. High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins. J Lipid Res. 2005 Apr; 46(4):769-78. Schneider M, Witztum JL, Young SG, Ludwig EH, Miller ER, Tsimikas S, Curtiss LK, Marcovina SM, Taylor JM, Lawn RM, Innerarity TL, Pitas RE. PMID: 15654123.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    354. Highlights of the year in JACC 2004. J Am Coll Cardiol. 2005 Jan 04; 45(1):137-53. Demaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Narula J, Sahn D, Tsimikas S. PMID: 15629388.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    355. Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization. Arterioscler Thromb Vasc Biol. 2004 Dec; 24(12):2307-12. Torzewski M, Shaw PX, Han KR, Shortal B, Lackner KJ, Witztum JL, Palinski W, Tsimikas S. PMID: 15528482.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    356. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 2004 Sep 14; 110(11):1406-12. Tsimikas S, Witztum JL, Miller ER, Sasiela WJ, Szarek M, Olsson AG, Schwartz GG, Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators. PMID: 15353498.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCellsCTClinical Trials
    357. Concomitant coronary and multiple arch vessel stenoses in patients treated with external beam radiation: pathophysiological basis and endovascular treatment. Catheter Cardiovasc Interv. 2004 Jul; 62(3):385-90. Cavendish JJ, Berman BJ, Schnyder G, Kerber C, Mahmud E, Turi ZG, Blanchard D, Tsimikas S. PMID: 15224309.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    358. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein. Circulation. 2004 Jun 29; 109(25):3164-70. Tsimikas S, Lau HK, Han KR, Shortal B, Miller ER, Segev A, Curtiss LK, Witztum JL, Strauss BH. PMID: 15184281.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    359. Severe ostial saphenous vein graft disease leading to acute coronary syndromes following proximal aorto-saphenous anastomoses with the symmetry bypass connector device: is it a suture device or a "stent"? J Am Coll Cardiol. 2004 Jan 07; 43(1):133-9. Cavendish JJ, Penny WF, Madani MM, Keramati S, Ben-Yehuda O, Blanchard DG, Mahmud E, Perricone A, Tsimikas S. PMID: 14715195.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    360. Highlights of the year in JACC 2003. J Am Coll Cardiol. 2003 Dec 17; 42(12):2156-66. DeMaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Tsimikas S. PMID: 15560019.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    361. Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). J Biol Chem. 2003 Dec 26; 278(52):52841-7. Edelstein C, Pfaffinger D, Hinman J, Miller E, Lipkind G, Tsimikas S, Bergmark C, Getz GS, Witztum JL, Scanu AM. PMID: 14557258.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    362. Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2003 Mar; 111(6):897-906. Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M, Kodama T, Tsimikas S, Witztum JL, Lu ML, Sakara Y, Chin MT, Libby P, Shi GP. PMID: 12639996; PMCID: PMC153760.
      View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
    363. Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J Am Coll Cardiol. 2003 Feb 05; 41(3):360-70. Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E, Juliano J, Witztum JL. PMID: 12575961.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    364. Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century. J Am Coll Cardiol. 2002 Dec 18; 40(12):2122-4. Tsimikas S, Witztum JL. PMID: 12505223.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    365. Noninvasive imaging of oxidized low-density lipoprotein in atherosclerotic plaques with tagged oxidation-specific antibodies. Am J Cardiol. 2002 Nov 21; 90(10C):22L-27L. Tsimikas S. PMID: 12459423.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    366. Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. J Am Soc Nephrol. 2002 Jun; 13(6):1673-81. Palinski W, Tsimikas S. PMID: 12039998.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    367. Non-invasive imaging of vulnerable plaques by molecular targeting of oxidized LDL with tagged oxidation-specific antibodies. J Cell Biochem Suppl. 2002; 39:138-46. Tsimikas S, Shaw PX. PMID: 12552613.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    368. Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo. Arterioscler Thromb Vasc Biol. 2001 Aug; 21(8):1333-9. Shaw PX, Hörkkö S, Tsimikas S, Chang MK, Palinski W, Silverman GJ, Chen PP, Witztum JL. PMID: 11498462.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    369. Common femoral artery anatomy is influenced by demographics and comorbidity: implications for cardiac and peripheral invasive studies. Catheter Cardiovasc Interv. 2001 Jul; 53(3):289-95. Schnyder G, Sawhney N, Whisenant B, Tsimikas S, Turi ZG. PMID: 11458402.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    370. Relationship between the heparin management test and the HemoTec activated clotting time in patients undergoing percutaneous coronary intervention. J Thromb Thrombolysis. 2001 May; 11(3):217-21. Tsimikas S, Beyer R, Hassankhani A. PMID: 11577260.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    371. Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk. Circulation. 2001 Apr 17; 103(15):1930-2. Tsimikas S, Witztum JL. PMID: 11306518.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    372. Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2001 Jan; 21(1):95-100. Tsimikas S, Palinski W, Witztum JL. PMID: 11145939.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    373. In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression. Arterioscler Thromb Vasc Biol. 2000 Mar; 20(3):689-97. Tsimikas S, Shortal BP, Witztum JL, Palinski W. PMID: 10712392.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    374. Spontaneous coronary artery dissection in patients with renal transplantation. J Invasive Cardiol. 1999 May; 11(5):316-21. Tsimikas S, Giordano FJ, Tarazi RY, Beyer RW. PMID: 10745540.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    375. LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. Arterioscler Thromb Vasc Biol. 1999 Jan; 19(1):122-30. Tsimikas S, Philis-Tsimikas A, Alexopoulos S, Sigari F, Lee C, Reaven PD. PMID: 9888874.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    376. Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo. J Nucl Cardiol. 1999 Jan-Feb; 6(1 Pt 1):41-53. Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. PMID: 10070840.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    377. The role of dietary fatty acids in lipoprotein oxidation and atherosclerosis. Curr Opin Lipidol. 1998 Aug; 9(4):301-7. Tsimikas S, Reaven PD. PMID: 9739484.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    378. Subintimal wire position during angioplasty of a chronic total coronary occlusion: detection and subsequent procedural guidance by intravascular ultrasound. Cathet Cardiovasc Diagn. 1995 Jul; 35(3):262-5. Kimura BJ, Tsimikas S, Bhargava V, DeMaria AN, Penny WF. PMID: 7553837.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    379. Aspergillus brain abscess complicating allergic Aspergillus sinusitis. J Allergy Clin Immunol. 1994 Aug; 94(2 Pt 1):264-7. Tsimikas S, Hollingsworth HM, Nash G. PMID: 8064081.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    380. Influence of beta-adrenergic stimulation and contraction frequency on rat heart interstitial adenosine. Circ Res. 1990 Feb; 66(2):457-68. Fenton RA, Tsimikas S, Dobson JG. PMID: 2153472.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    381. Inhibition of fructose bisphosphatase and stimulation of phosphofructokinase by a stable isosteric phosphonate analog of fructose 2,6-bisphosphate. Arch Biochem Biophys. 1986 Feb 15; 245(1):282-6. McClard RW, Tsimikas S, Schriver KE. PMID: 3004359.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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