Sotirios Tsimikas

Title(s)Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Oxidation-specific nanoparticles for imaging atherosclerosis
    NIH R01HL119828Aug 21, 2013 - Jul 31, 2019
    Role: Principal Investigator
    IMAGING ATHEROSCLEROSIS WITH SPECIFIC ANTIBODIES
    NIH K08HL003793Dec 15, 1997 - Nov 30, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome. N Engl J Med. 2024 Apr 07. Stroes ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, Arca M, Ballantyne CM, Soran H, Prohaska TA, Xia S, Ginsberg HN, Witztum JL, Tsimikas S, Balance Investigators. PMID: 38587247.
      View in: PubMed   Mentions:
    2. Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk. N Engl J Med. 2024 Apr 07. Bergmark BA, Marston NA, Prohaska TA, Alexander VJ, Zimerman A, Moura FA, Murphy SA, Goodrich EL, Zhang S, Gaudet D, Karwatowska-Prokopczuk E, Tsimikas S, Giugliano RP, Sabatine MS, Bridge–TIMI 73a Investigators. PMID: 38587249.
      View in: PubMed   Mentions:
    3. Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis. J Clin Invest. 2024 Mar 01; 134(5). Nakamura Y, Kulkarni NN, Takahashi T, Alimohamadi H, Dokoshi T, Liu E, Shia M, Numata T, Luo EW, Gombart AF, Yang X, Secrest P, Gordts PL, Tsimikas S, Wong GC, Gallo RL. PMID: 38194294; PMCID: PMC10904043.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial. PLoS One. 2024; 19(2):e0299197. Tomazini BM, Tramujas L, Medrado FA, Gomes SPDC, Negrelli KL, Murinize GS, Santos RHN, Vianna BMP, Piotto BF, Veiga TS, Santos BRD, Peneluppi Horak AC, Lemos OMC, Lopes MA, Olicheski BB, Campones DL, Peixoto LAA, Basilio ADAC, Gebara OCE, Lopes ATA, Saconato H, Valeis N, Miranda TA, Laranjeira LN, Santucci EV, Carlin AF, Esko JD, Gordts PLSM, Tsimikas S, Cavalcanti AB. PMID: 38394069; PMCID: PMC10889621.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    5. Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance. Cardiovasc Res. 2024 02 17; 119(18):2843-2857. Packard CJ, Pirillo A, Tsimikas S, Ference BA, Catapano AL. PMID: 38039351.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia. N Engl J Med. 2024 Feb 01; 390(5):476-477. Alexander VJ, Karwatowska-Prokopczuk E, Prohaska TA, Li L, Geary RS, Gouni-Berthold I, Oral EA, Hegele RA, Stroes ESG, Witztum JL, Tsimikas S. PMID: 38294982.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Aspirin and Cardiovascular Risk in Individuals With Elevated Lipoprotein(a): The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2024 Feb 06; 13(3):e033562. Bhatia HS, Trainor P, Carlisle S, Tsai MY, Criqui MH, DeFilippis A, Tsimikas S. PMID: 38293935.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation. Arterioscler Thromb Vasc Biol. 2024 03; 44(3):720-740. Dzobo KE, Cupido AJ, Mol BM, Stiekema LCA, Versloot M, Winkelmeijer M, Peter J, Pennekamp AM, Havik SR, Vaz FM, van Weeghel M, Prange KHM, Levels JHM, de Winther MPJ, Tsimikas S, Groen AK, Stroes ESG, de Kleijn DPV, Kroon J. PMID: 38269588; PMCID: PMC10880937.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Particle Number and Characteristics of Lipoprotein(a), LDL, and apoB: Perspectives on Contributions to ASCVD. J Am Coll Cardiol. 2024 Jan 23; 83(3):396-400. Tsimikas S, Bittner V. PMID: 38233013.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Safety and Tolerability of GalNAc3-Conjugated Antisense Drugs Compared to the Same-Sequence 2'-O-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data. Nucleic Acid Ther. 2024 Feb; 34(1):18-25. Baker BF, Xia S, Partridge W, Engelhardt JA, Tsimikas S, Crooke ST, Bhanot S, Geary RS. PMID: 38227794.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    11. Atherothrombotic and thrombolytic biomarkers in incident stroke and atrial fibrillation-related stroke: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2024 Mar; 390:117451. Lidani KCF, Trainor PJ, Bhatia HS, Nasir K, Blaha MJ, Tsai MY, Gottesman RF, Post WS, Thanassoulis G, Tsimikas S, Heckbert SR, DeFilippis AP. PMID: 38262276.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Effect of Eplontersen on Cardiac Structure and Function in Patients With Hereditary Transthyretin Amyloidosis. J Card Fail. 2023 Dec 07. Masri A, Maurer MS, Claggett BL, Kulac I, Waddington Cruz M, Conceição I, Weiler M, Berk JL, Gertz M, Gillmore JD, Rush S, Chen J, Zhou W, Kwoh J, Duran JM, Tsimikas S, Solomon SD. PMID: 38065307.
      View in: PubMed   Mentions:    Fields:    
    13. Lipoprotein(a) levels and carotid intima-media thickness in children: A 20-year follow-up study. J Clin Lipidol. 2023 Nov 27. de Boer LM, Hutten BA, Tsimikas S, Yeang C, Zwinderman AH, Kroon J, Revers A, Kastelein JJP, Wiegman A. PMID: 38065715.
      View in: PubMed   Mentions:    Fields:    
    14. Lipoprotein(a), platelet function and cardiovascular disease. Nat Rev Cardiol. 2023 Nov 08. Bhatia HS, Becker RC, Leibundgut G, Patel M, Lacaze P, Tonkin A, Narula J, Tsimikas S. PMID: 37938756.
      View in: PubMed   Mentions: 1     Fields:    
    15. Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease. Circulation. 2024 Jan 30; 149(5):391-401. Rogers MA, Bartoli-Leonard F, Zheng KH, Small AM, Chen HY, Clift CL, Asano T, Kuraoka S, Blaser MC, Perez KA, Natarajan P, Yeang C, Stroes ESG, Tsimikas S, Engert JC, Thanassoulis G, O'Donnell CJ, Aikawa M, Singh SA, Aikawa E. PMID: 37937463; PMCID: PMC10842618.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Oxidized phospholipids in cardiovascular disease. Nat Rev Cardiol. 2024 Mar; 21(3):170-191. Tsimikas S, Witztum JL. PMID: 37848630.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Corrigendum to "Volanesorsen and triglyceride levels in familial chylomicronemia syndrome: Long-term efficacy and safety data from patients in an open-label extension trial" [Journal of Clinical Lipidology, Volume 17, Issue 3, May-June 2023, Pages 342-355]. J Clin Lipidol. 2023 Oct 13. Witztum JL, Gaudet D, Arca M, Jones A, Soran H, Gouni-Berthold I, Stroes ESG, Alexander VJ, Jones R, Watts L, Xia S, Tsimikas S. PMID: 38565460.
      View in: PubMed   Mentions:    Fields:    
    18. Relating Lipoprotein(a) Concentrations to Cardiovascular Event Risk After Acute Coronary Syndrome: A Comparison of 3 Tests. Circulation. 2024 Jan 16; 149(3):192-203. Szarek M, Reijnders E, Jukema JW, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, Ruhaak LR, Schwertfeger M, Tsimikas S, White HD, Steg PG, Cobbaert C, Schwartz GG, ODYSSEY OUTCOMES Investigators. PMID: 37632469; PMCID: PMC10782942.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Lipoprotein(a) and the pooled cohort equations for ASCVD risk prediction: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2023 09; 381:117217. Bhatia HS, Rikhi R, Allen TS, Yeang C, Guan W, Garg PK, Tsai MY, Criqui MH, Shapiro MD, Tsimikas S. PMID: 37607461; PMCID: PMC10659123.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Lipoprotein(a) and carotid intima-media thickness in children with familial hypercholesterolaemia in the Netherlands: a 20-year follow-up study. Lancet Diabetes Endocrinol. 2023 09; 11(9):667-674. de Boer LM, Wiegman A, Kroon J, Tsimikas S, Yeang C, Peletier MC, Revers A, Kastelein JJP, Zwinderman AH, Hutten BA. PMID: 37487514.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Reducing reductionism: addressing risk for atherosclerotic cardiovascular disease by apolipoprotein proteomics. Eur Heart J. 2023 Jul 14; 44(27):2420-2422. Schmidt LE, Speidl WS, Tsimikas S, Mayr M. PMID: 37264561.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Clinical trials to improve outcomes in patients with elevated Lp(a) undergoing PCI: The time has arrived. J Clin Lipidol. 2023 Sep-Oct; 17(5):567-570. Tsimikas S, Bhatia HS, Erlinge D. PMID: 37419784.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. On-treatment platelet reactivity through the thromboxane A2 or P2Y12 platelet receptor pathways is not affected by pelacarsen. J Thromb Thrombolysis. 2023 Aug; 56(2):226-232. Karwatowska-Prokopczuk E, Li L, Yang J, Witztum JL, Tsimikas S. PMID: 37338713.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    24. Lipoprotein(a) and coronary artery calcium in comparison with other lipid biomarkers: The multi-ethnic study of atherosclerosis. J Clin Lipidol. 2023 Jul-Aug; 17(4):538-548. Jackson CL, Garg PK, Guan W, Tsai MY, Criqui MH, Tsimikas S, Bhatia HS. PMID: 37357049; PMCID: PMC10691212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nat Rev Cardiol. 2023 Jun; 20(6):429. Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A, Zhou F, Moreira AL, Côté N, Tsimikas S, Fuster V, Gandy S, Bonow RO, Gursky O, Narula J. PMID: 36807395.
      View in: PubMed   Mentions:    Fields:    
    26. High immunoglobulin-M levels to oxidation-specific epitopes are associated with lower risk of acute myocardial infarction. J Lipid Res. 2023 06; 64(6):100391. Taleb A, Willeit P, Amir S, Perkmann T, Kozma MO, Watzenböck ML, Binder CJ, Witztum JL, Tsimikas S. PMID: 37211249; PMCID: PMC10275726.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Effects of mixed nut consumption on LDL cholesterol, lipoprotein(a), and other cardiometabolic risk factors in overweight and obese adults. Nutr Metab Cardiovasc Dis. 2023 Aug; 33(8):1529-1538. Nora CL, Zhang L, Castro RJ, Marx A, Carman HB, Lum T, Tsimikas S, Hong MY. PMID: 37263914.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Lipoprotein(a), Oxidized Phospholipids, and Coronary Artery Disease Severity and Outcomes. J Am Coll Cardiol. 2023 05 09; 81(18):1780-1792. Gilliland TC, Liu Y, Mohebi R, Miksenas H, Haidermota S, Wong M, Hu X, Cristino JR, Browne A, Plutzky J, Tsimikas S, Januzzi JL, Natarajan P. PMID: 37137588; PMCID: PMC10824318.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    29. APOC3 inhibition with volanesorsen reduces hepatic steatosis in patients with severe hypertriglyceridemia. J Clin Lipidol. 2023 May-Jun; 17(3):406-411. Prohaska TA, Alexander VJ, Karwatowska-Prokopczuk E, Tami J, Xia S, Witztum JL, Tsimikas S. PMID: 37164837.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification. Circulation. 2023 05 16; 147(20):1518-1533. Gollmann-Tepeköylü C, Graber M, Hirsch J, Mair S, Naschberger A, Pölzl L, Nägele F, Kirchmair E, Degenhart G, Demetz E, Hilbe R, Chen HY, Engert JC, Böhm A, Franz N, Lobenwein D, Lener D, Fuchs C, Weihs A, Töchterle S, Vogel GF, Schweiger V, Eder J, Pietschmann P, Seifert M, Kronenberg F, Coassin S, Blumer M, Hackl H, Meyer D, Feuchtner G, Kirchmair R, Troppmair J, Krane M, Weiss G, Tsimikas S, Thanassoulis G, Grimm M, Rupp B, Huber LA, Zhang SY, Casanova JL, Tancevski I, Holfeld J. PMID: 37013819; PMCID: PMC10192061.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    31. Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2023 04 04; 81(13):1248-1259. Trainor PJ, Brambatti M, Carlisle SM, Mullick AE, Shah SJ, Kahlon T, Mostacero DO, Mousavi H, Morgan ES, Tami Y, Michos ED, Ouyang P, Tsimikas S, DeFilippis AP. PMID: 36990544; PMCID: PMC10352958.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Impact of C-reactive protein levels on lipoprotein(a)-associated aortic stenosis incidence and progression. Eur Heart J Open. 2023 Mar; 3(2):oead032. Girard A, Gaillard E, Puri R, Capoulade R, Chan KL, Paulin A, Manikpurage HD, Dumesnil J, Tam JW, Teo KK, Couture C, Wareham NJ, Clavel MA, Stroes ESG, Mathieu P, Thériault S, Tsimikas S, Pibarot P, Boekholdt SM, Arsenault BJ. PMID: 37077580; PMCID: PMC10108885.
      View in: PubMed   Mentions: 2  
    33. Volanesorsen and triglyceride levels in familial chylomicronemia syndrome: Long-term efficacy and safety data from patients in an open-label extension trial. J Clin Lipidol. 2023 May-Jun; 17(3):342-355. Witztum JL, Gaudet D, Arca M, Jones A, Soran H, Gouni-Berthold I, Stroes ESG, Alexander VJ, Jones R, Watts L, Xia S, Tsimikas S. PMID: 37100699.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nat Rev Cardiol. 2023 06; 20(6):418-428. Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A, Zhou F, Moreira AL, Côté N, Tsimikas S, Fuster V, Gandy S, Bonow RO, Gursky O, Narula J. PMID: 36624274; PMCID: PMC10199673.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Association of Lp(a) (Lipoprotein[a]) and Hypertension in Primary Prevention of Cardiovascular Disease: The MESA. Hypertension. 2023 02; 80(2):352-360. Rikhi R, Bhatia HS, Schaich CL, Ashburn N, Tsai MY, Michos ED, Chevli PA, Herrington DM, Tsimikas S, Shapiro MD. PMID: 36511156; PMCID: PMC9983733.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    36. Efficacy and safety of pelacarsen in lowering Lp(a) in healthy Japanese subjects. J Clin Lipidol. 2023 Jan-Feb; 17(1):181-188. Karwatowska-Prokopczuk E, Lesogor A, Yan JH, Hurh E, Hoenlinger A, Margolskee A, Xia S, Tsimikas S. PMID: 36529659.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Integrated Assessment of Phase 2 Data on GalNAc3-Conjugated 2'-O-Methoxyethyl-Modified Antisense Oligonucleotides. Nucleic Acid Ther. 2023 01; 33(1):72-80. Baker BF, Xia S, Partridge W, Kwoh TJ, Tsimikas S, Bhanot S, Geary RS. PMID: 36454263; PMCID: PMC10623620.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    38. Lipoprotein(a) and LDL-C: The Relevance of Equivalence. J Am Coll Cardiol. 2022 11 22; 80(21):2011-2013. Morris PB, Narula J, Tsimikas S. PMID: 36396202.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation. Lipids Health Dis. 2022 Nov 01; 21(1):113. Ruder S, Mansfield B, Immelman AR, Varki N, Miu P, Raal F, Tsimikas S. PMID: 36320028; PMCID: PMC9623907.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes. J Am Coll Cardiol. 2022 10 04; 80(14):1287-1298. Lacaze P, Bakshi A, Riaz M, Polekhina G, Owen A, Bhatia HS, Natarajan P, Wolfe R, Beilin L, Nicholls SJ, Watts GF, McNeil JJ, Tonkin AM, Tsimikas S. PMID: 36175048; PMCID: PMC10025998.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    41. Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease. Open Heart. 2022 10; 9(2). Nissen SE, Wolski K, Cho L, Nicholls SJ, Kastelein J, Leitersdorf E, Landmesser U, Blaha M, Lincoff AM, Morishita R, Tsimikas S, Liu J, Manning B, Kozlovski P, Lesogor A, Thuren T, Shibasaki T, Matei F, Silveira FS, Meunch A, Bada A, Vijan V, Bruun NE, Nordestgaard BG, Lp(a)HERITAGE Investigators. PMID: 36252994; PMCID: PMC9577925.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    42. Assessment of efficacy and safety of volanesorsen for treatment of metabolic complications in patients with familial partial lipodystrophy: Results of the BROADEN study: Volanesorsen in FPLD; The BROADEN Study. J Clin Lipidol. 2022 Sep 22. Oral EA, Garg A, Tami J, Huang EA, O'Dea LSL, Schmidt H, Tiulpakov A, Mertens A, Alexander VJ, Watts L, Hurh E, Witztum JL, Geary RS, Tsimikas S. PMID: 36402670.
      View in: PubMed   Mentions: 8     Fields:    
    43. Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 08 30; 80(9):934-946. Tsimikas S, Marcovina SM. PMID: 36007992.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering. JCI Insight. 2022 07 08; 7(13). Ramms B, Patel S, Sun X, Pessentheiner AR, Ducasa GM, Mullick AE, Lee RG, Crooke RM, Tsimikas S, Witztum JL, Gordts PL. PMID: 35653195; PMCID: PMC9310539.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    45. Oxidized phospholipids on apolipoprotein B-100 versus plasminogen and risk of coronary heart disease in the PROCARDIS study. Atherosclerosis. 2022 08; 354:15-22. Clarke R, Hammami I, Sherliker P, Valdes-Marquez E, Watkins H, Hill M, Yang X, Tsimikas S, Hopewell JC, PROCARDIS Consortium. PMID: 35803063.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    46. Effect of olezarsen targeting APOC-III on lipoprotein size and particle number measured by NMR in patients with hypertriglyceridemia. J Clin Lipidol. 2022 Sep-Oct; 16(5):617-625. Karwatowska-Prokopczuk E, Tardif JC, Gaudet D, Ballantyne CM, Shapiro MD, Moriarty PM, Baum SJ, Amour ES, Alexander VJ, Xia S, Otvos JD, Witztum JL, Tsimikas S, Olezarsen Trial Investigators. PMID: 35902351.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    47. Development and validation of an isoform-independent monoclonal antibody-based ELISA for measurement of lipoprotein(a). J Lipid Res. 2022 08; 63(8):100239. Marcovina SM, Navabi N, Allen S, Gonen A, Witztum JL, Tsimikas S. PMID: 35688187; PMCID: PMC9352967.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    48. Apolipoprotein C-III reduction in subjects with moderate hypertriglyceridaemia and at high cardiovascular risk. Eur Heart J. 2022 04 06; 43(14):1401-1412. Tardif JC, Karwatowska-Prokopczuk E, Amour ES, Ballantyne CM, Shapiro MD, Moriarty PM, Baum SJ, Hurh E, Bartlett VJ, Kingsbury J, Figueroa AL, Alexander VJ, Tami J, Witztum JL, Geary RS, O'Dea LSL, Tsimikas S, Gaudet D. PMID: 35025993; PMCID: PMC8986458.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    49. Effect of Pelacarsen on Lipoprotein(a) Cholesterol and Corrected Low-Density Lipoprotein Cholesterol. J Am Coll Cardiol. 2022 03 22; 79(11):1035-1046. Yeang C, Karwatowska-Prokopczuk E, Su F, Dinh B, Xia S, Witztum JL, Tsimikas S. PMID: 35300814; PMCID: PMC8972555.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    50. Atherothrombotic factors and atherosclerotic cardiovascular events: the multi-ethnic study of atherosclerosis. Eur Heart J. 2022 03 07; 43(10):971-981. DeFilippis AP, Trainor PJ, Thanassoulis G, Brumback LC, Post WS, Tsai MY, Tsimikas S. PMID: 34508626; PMCID: PMC8899529.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial. Atherosclerosis. 2022 04; 346:68-74. Ren S, Hansbro PM, Srikusalanukul W, Horvat JC, Hunter T, Brown AC, Peel R, Faulkner J, Evans TJ, Li SC, Newby D, Hure A, Abhayaratna WP, Tsimikas S, Gonen A, Witztum JL, Attia J, AUSPICE investigators. PMID: 35290813.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    52. Lipoprotein(a) and Coronary Calcium: Clinical Management and Potential Design of Primary Prevention Trials. J Am Coll Cardiol. 2022 03 01; 79(8):769-771. Tsimikas S. PMID: 35210031.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    53. Trends in testing and prevalence of elevated Lp(a) among patients with aortic valve stenosis. Atherosclerosis. 2022 05; 349:144-150. Bhatia HS, Ma GS, Taleb A, Wilkinson M, Kahn AM, Cotter B, Yeang C, DeMaria AN, Patel MP, Mahmud E, Reeves RR, Tsimikas S. PMID: 35144769; PMCID: PMC9674369.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Lipoprotein(a) and CT Angiography: Novel Insights Into High-Risk Plaque Progression. J Am Coll Cardiol. 2022 01 25; 79(3):234-237. Tsimikas S, Narula J. PMID: 35057908.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Lipoprotein(a), venous thromboembolism and COVID-19: A pilot study. Atherosclerosis. 2022 01; 341:43-49. Nurmohamed NS, Collard D, Reeskamp LF, Kaiser Y, Kroon J, Tromp TR, Amsterdam UMC Covid-19 Biobank, van den Born BH, Coppens M, Vlaar APJ, Beudel M, van de Beek D, van Es N, Moriarty PM, Tsimikas S, Stroes ESG. PMID: 34995986; PMCID: PMC8690577.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    56. Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. Circulation. 2021 12 14; 144(24):1940-1954. Dou H, Kotini A, Liu W, Fidler T, Endo-Umeda K, Sun X, Olszewska M, Xiao T, Abramowicz S, Yalcinkaya M, Hardaway B, Tsimikas S, Que X, Bick A, Emdin C, Natarajan P, Papapetrou EP, Witztum JL, Wang N, Tall AR. PMID: 34846914; PMCID: PMC8663540.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    57. Longitudinal Assessment of Lipoprotein(a) Levels in Perinatally HIV-Infected Children and Adolescents. Viruses. 2021 10 14; 13(10). van Genderen JG, Van den Hof M, de Boer CG, Jansen HPG, van Deventer SJH, Tsimikas S, Witztum JL, Kastelein JJP, Pajkrt D. PMID: 34696496; PMCID: PMC8539147.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    58. PCSK9 Activity Is Potentiated Through HDL Binding. Circ Res. 2021 11 12; 129(11):1039-1053. Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE, Hall WL, Notdurfter M, Rungger G, Paulweber B, Willeit J, Kiechl S, Levkau B, Mayr M. PMID: 34601896; PMCID: PMC8579991.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    59. Always Present, But Now Rediscovered: Lp(a) as a Predictor of Long-Term Outcomes in PCI. JACC Cardiovasc Interv. 2021 09 27; 14(18):2069-2072. Tsimikas S, Reeves RR, Patel MP. PMID: 34556281.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    60. PCSK9 Inhibition and Oxidized Phospholipids. J Am Coll Cardiol. 2021 09 21; 78(12):1288-1289. Bhatia HS, Yeang C, Baruch A, Yang X, Stroes ESG, Tsimikas S. PMID: 34531030; PMCID: PMC10198455.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    61. Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. Aging Cell. 2021 08; 20(8):e13442. Palmieri M, Almeida M, Nookaew I, Gomez-Acevedo H, Joseph TE, Que X, Tsimikas S, Sun X, Manolagas SC, Witztum JL, Ambrogini E. PMID: 34278710; PMCID: PMC8373359.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    62. Association of lipoprotein(a) with intrinsic and on-clopidogrel platelet reactivity. J Thromb Thrombolysis. 2022 Jan; 53(1):1-9. Kille A, Nührenberg T, Franke K, Valina CM, Leibundgut G, Tsimikas S, Neumann FJ, Hochholzer W. PMID: 34213715; PMCID: PMC8791920.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    63. Elevated lipoprotein(a) and the risk of stroke in children, young adults, and the elderly. Eur Heart J. 2021 06 07; 42(22):2197-2200. Tsimikas S. PMID: 34000000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    64. Antisense Inhibition of Angiotensinogen With IONIS-AGT-LRx: Results of Phase 1 and Phase 2 Studies. JACC Basic Transl Sci. 2021 Jun; 6(6):485-496. Morgan ES, Tami Y, Hu K, Brambatti M, Mullick AE, Geary RS, Bakris GL, Tsimikas S. PMID: 34222719; PMCID: PMC8246029.
      View in: PubMed   Mentions: 9  
    65. Emerging RNA Therapeutics to Lower Blood Levels of Lp(a): JACC Focus Seminar 2/4. J Am Coll Cardiol. 2021 03 30; 77(12):1576-1589. Tsimikas S, Moriarty PM, Stroes ES. PMID: 33766265.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    66. Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol. 2021 05; 9(5):264-275. Gouni-Berthold I, Alexander VJ, Yang Q, Hurh E, Steinhagen-Thiessen E, Moriarty PM, Hughes SG, Gaudet D, Hegele RA, O'Dea LSL, Stroes ESG, Tsimikas S, Witztum JL, COMPASS study group. PMID: 33798466.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCTClinical Trials
    67. Prevalence and influence of LPA gene variants and isoform size on the Lp(a)-lowering effect of pelacarsen. Atherosclerosis. 2021 05; 324:102-108. Karwatowska-Prokopczuk E, Clouet-Foraison N, Xia S, Viney NJ, Witztum JL, Marcovina SM, Tsimikas S. PMID: 33872986.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    68. The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26. Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697; PMCID: PMC8010724.
      View in: PubMed   Mentions: 2  
    69. Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy. Neurol Ther. 2021 Jun; 10(1):375-389. Coelho T, Ando Y, Benson MD, Berk JL, Waddington-Cruz M, Dyck PJ, Gillmore JD, Khella SL, Litchy WJ, Obici L, Monteiro C, Tai LJ, Viney NJ, Buchele G, Brambatti M, Jung SW, St L O'Dea L, Tsimikas S, Schneider E, Geary RS, Monia BP, Gertz M. PMID: 33638113; PMCID: PMC8140170.
      View in: PubMed   Mentions: 19  
    70. Novel method for quantification of lipoprotein(a)-cholesterol: implications for improving accuracy of LDL-C measurements. J Lipid Res. 2021; 62:100053. Yeang C, Witztum JL, Tsimikas S. PMID: 33636163; PMCID: PMC8042377.
      View in: PubMed   Mentions: 22     Fields:    
    71. Glucose Control in Patients Undergoing PCI: What Is the Optimal HbA1c for Long-Term Outcomes? JACC Cardiovasc Interv. 2021 02 22; 14(4):398-400. Tsimikas S, Bhatia HS. PMID: 33602436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):e82-e96. Choi SH, Agatisa-Boyle C, Gonen A, Kim A, Kim J, Alekseeva E, Tsimikas S, Miller YI. PMID: 33356389; PMCID: PMC8105271.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    73. Effect of bariatric surgery on plasma levels of oxidised phospholipids, biomarkers of oxidised LDL and lipoprotein(a). J Clin Lipidol. 2021 Mar-Apr; 15(2):320-331. Ho JH, Adam S, Liu Y, Azmi S, Dhage S, Syed AA, Ammori BJ, Donn R, Heald A, Gibson MJ, Malik RA, Yang X, Durrington PN, Tsimikas S, Soran H. PMID: 33518459.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    74. Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data. ESC Heart Fail. 2021 02; 8(1):652-661. Viney NJ, Guo S, Tai LJ, Baker BF, Aghajan M, Jung SW, Yu RZ, Booten S, Murray H, Machemer T, Burel S, Murray S, Buchele G, Tsimikas S, Schneider E, Geary RS, Benson MD, Monia BP. PMID: 33283485; PMCID: PMC7835591.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCTClinical Trials
    75. microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production. JCI Insight. 2020 12 03; 5(23). Dong J, He M, Li J, Pessentheiner A, Wang C, Zhang J, Sun Y, Wang WT, Zhang Y, Liu J, Wang SC, Huang PH, Gordts PL, Yuan ZY, Tsimikas S, Shyy JY. PMID: 33119548; PMCID: PMC7714402.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    76. The interconnection between lipoprotein(a), lipoprotein(a) cholesterol and true LDL-cholesterol in the diagnosis of familial hypercholesterolemia. Curr Opin Lipidol. 2020 12; 31(6):305-312. Yeang C, Willeit P, Tsimikas S. PMID: 33027223.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    77. Low-Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events. J Am Heart Assoc. 2020 12; 9(23):e016318. Willeit P, Yeang C, Moriarty PM, Tschiderer L, Varvel SA, McConnell JP, Tsimikas S. PMID: 33222611; PMCID: PMC7763787.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    78. Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial. Eur Heart J. 2020 11 21; 41(44):4245-4255. Szarek M, Bittner VA, Aylward P, Baccara-Dinet M, Bhatt DL, Diaz R, Fras Z, Goodman SG, Halvorsen S, Harrington RA, Jukema JW, Moriarty PM, Pordy R, Ray KK, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Investigators. PMID: 33051646; PMCID: PMC7724642.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    79. Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):458-464. Hoekstra M, Chen HY, Rong J, Dufresne L, Yao J, Guo X, Tsai MY, Tsimikas S, Post WS, Vasan RS, Rotter JI, Larson MG, Thanassoulis G, Engert JC. PMID: 33115273; PMCID: PMC7769958.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    80. Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia. Eur Heart J. 2020 10 21; 41(40):3936-3945. Gaudet D, Karwatowska-Prokopczuk E, Baum SJ, Hurh E, Kingsbury J, Bartlett VJ, Figueroa AL, Piscitelli P, Singleton W, Witztum JL, Geary RS, Tsimikas S, O'Dea LSL, Vupanorsen Study Investigators. PMID: 32860031; PMCID: PMC7750927.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCTClinical Trials
    81. From traditional pharmacological towards nucleic acid-based therapies for cardiovascular diseases. Eur Heart J. 2020 10 21; 41(40):3884-3899. Landmesser U, Poller W, Tsimikas S, Most P, Paneni F, Lüscher TF. PMID: 32350510.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    82. A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice. J Bone Miner Res. 2021 01; 36(1):170-185. Palmieri M, Kim HN, Gomez-Acevedo H, Que X, Tsimikas S, Jilka RL, Manolagas SC, Witztum JL, Ambrogini E. PMID: 32990984; PMCID: PMC7855899.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    83. Lipoprotein(a) and Its Potential Association with Thrombosis and Inflammation in COVID-19: a Testable Hypothesis. Curr Atheroscler Rep. 2020 07 25; 22(9):48. Moriarty PM, Gorby LK, Stroes ES, Kastelein JP, Davidson M, Tsimikas S. PMID: 32710255; PMCID: PMC7381416.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCellsPHPublic Health
    84. Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a). J Lipid Res. 2020 09; 61(9):1263-1270. Gonen A, Yang X, Yeang C, Alekseeva E, Koschinsky M, Witztum JL, Boffa M, Tsimikas S. PMID: 32641432; PMCID: PMC7469883.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    85. Treatment with Volanesorsen, a 2'-O-Methoxyethyl-Modified Antisense Oligonucleotide Targeting APOC3 mRNA, Does Not Affect the QTc Interval in Healthy Volunteers. Nucleic Acid Ther. 2020 08; 30(4):198-206. Watts LM, Karwatowska-Prokopczuk E, Hurh E, Alexander VJ, Balogh K, O'Dea L, Geary RS, Tsimikas S. PMID: 32589506; PMCID: PMC7415887.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    86. Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a). Eur Heart J. 2020 06 21; 41(24):2262-2271. Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. PMID: 32268367; PMCID: PMC7308540.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    87. Statin therapy increases lipoprotein(a) levels. Eur Heart J. 2020 06 21; 41(24):2275-2284. Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31111151.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    88. Lipoprotein(a) Reduction in Persons with Cardiovascular Disease. Reply. N Engl J Med. 2020 05 21; 382(21):e65. Tsimikas S, Karwatowska-Prokopczuk E, Xia S. PMID: 32433854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    89. Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes. Int J Cardiol. 2020 09 15; 315:81-85. Schnitzler JG, Poels K, Stiekema LCA, Yeang C, Tsimikas S, Kroon J, Stroes ESG, Lutgens E, Seijkens TTP. PMID: 32387421.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    90. High-Density Lipoproteins Are the Main Carriers of PCSK9 in the Circulation. J Am Coll Cardiol. 2020 03 31; 75(12):1495-1497. Burnap SA, Joshi A, Tsimikas S, Fernández-Hernando C, Kiechl S, Berry SE, Hall W, Levkau B, Mayr M. PMID: 32216920.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    91. The dedicated "Lp(a) clinic": A concept whose time has arrived? Atherosclerosis. 2020 05; 300:1-9. Tsimikas S, Stroes ESG. PMID: 32234580.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    92. Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation. Circ Res. 2020 05 08; 126(10):1346-1359. Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. PMID: 32160811; PMCID: PMC7208285.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    93. ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis. Heart. 2020 05; 106(10):738-745. Capoulade R, Torzewski M, Mayr M, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam J, Teo KK, Burnap SA, Schmid J, Gobel N, Franke UFW, Sanchez A, Witztum JL, Yang X, Yeang C, Arsenault B, Després JP, Pibarot P, Tsimikas S. PMID: 32054669.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    94. Ancient Remedy for a Modern Disease: Will Celastrol Become a Treatment for Aortic Valve Stenosis? JACC Basic Transl Sci. 2020 Jan; 5(1):50-52. Yeang C, Tsimikas S. PMID: 32043488; PMCID: PMC7000881.
      View in: PubMed   Mentions: 2  
    95. Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome. J Am Coll Cardiol. 2020 01 21; 75(2):133-144. Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Committees and Investigators. PMID: 31948641.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    96. Familial hypercholesterolemia and elevated lipoprotein(a): double heritable risk and new therapeutic opportunities. J Intern Med. 2020 01; 287(1):2-18. Vuorio A, Watts GF, Schneider WJ, Tsimikas S, Kovanen PT. PMID: 31858669.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    97. Statins and increases in Lp(a): an inconvenient truth that needs attention. Eur Heart J. 2020 01 01; 41(1):192-193. Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31893480.
      View in: PubMed   Mentions: 11     Fields:    
    98. Lipoprotein(a) Reduction in Persons with Cardiovascular Disease. N Engl J Med. 2020 01 16; 382(3):244-255. Tsimikas S, Karwatowska-Prokopczuk E, Gouni-Berthold I, Tardif JC, Baum SJ, Steinhagen-Thiessen E, Shapiro MD, Stroes ES, Moriarty PM, Nordestgaard BG, Xia S, Guerriero J, Viney NJ, O'Dea L, Witztum JL, AKCEA-APO(a)-LRx Study Investigators. PMID: 31893580.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansCTClinical Trials
    99. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metab. 2020 01 07; 31(1):189-206.e8. Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. PMID: 31761566; PMCID: PMC7028360.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    100. Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial. Circulation. 2020 02 25; 141(8):624-636. Damask A, Steg PG, Schwartz GG, Szarek M, Hagström E, Badimon L, Chapman MJ, Boileau C, Tsimikas S, Ginsberg HN, Banerjee P, Manvelian G, Pordy R, Hess S, Overton JD, Lotta LA, Yancopoulos GD, Abecasis GR, Baras A, Paulding C, Regeneron Genetics Center and the ODYSSEY OUTCOMES Investigators. PMID: 31707832.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    101. Erratum: A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 Nov; 60(11):1979. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 31676683; PMCID: PMC6824499.
      View in: PubMed   Mentions:    Fields:    
    102. Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis. J Lipid Res. 2019 12; 60(12):2082-2089. Boffa MB, Marar TT, Yeang C, Viney NJ, Xia S, Witztum JL, Koschinsky ML, Tsimikas S. PMID: 31551368; PMCID: PMC6889713.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    103. Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis. Circ Res. 2019 10 25; 125(10):e55-e70. Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen A, McSkimming C, Marshall MA, Garmey JC, Taylor AM, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, McNamara CA. PMID: 31549940; PMCID: PMC6830526.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    104. PCSK9 loss-of-function variants and Lp(a) phenotypes among black US adults. J Lipid Res. 2019 11; 60(11):1946-1952. Mefford MT, Marcovina SM, Bittner V, Cushman M, Brown TM, Farkouh ME, Tsimikas S, Monda KL, López JAG, Muntner P, Rosenson RS. PMID: 31511398; PMCID: PMC6824493.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    105. Elevated Lipoprotein(a) in Perinatally HIV-Infected Children Compared With Healthy Ethnicity-Matched Controls. Open Forum Infect Dis. 2019 Sep; 6(9):ofz301. Van den Hof M, Klein Haneveld MJ, Blokhuis C, Scherpbier HJ, Jansen HPG, Kootstra NA, Dallinga-Thie GM, Van Deventer SJH, Tsimikas S, Pajkrt D, NOVICE study group . PMID: 31660394; PMCID: PMC6736182.
      View in: PubMed   Mentions: 3  
    106. N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels. Eur Heart J. 2019 09 01; 40(33):2785-2796. Alexander VJ, Xia S, Hurh E, Hughes SG, O'Dea L, Geary RS, Witztum JL, Tsimikas S. PMID: 31329855; PMCID: PMC6736334.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCTClinical Trials
    107. The challenges of measuring Lp(a): A fight against Hydra? Atherosclerosis. 2019 10; 289:181-183. Kronenberg F, Tsimikas S. PMID: 31495537.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    108. Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome. N Engl J Med. 2019 08 08; 381(6):531-542. Witztum JL, Gaudet D, Freedman SD, Alexander VJ, Digenio A, Williams KR, Yang Q, Hughes SG, Geary RS, Arca M, Stroes ESG, Bergeron J, Soran H, Civeira F, Hemphill L, Tsimikas S, Blom DJ, O'Dea L, Bruckert E. PMID: 31390500.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansCTClinical Trials
    109. ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance. J Lipid Res. 2019 08; 60(8):1379-1395. Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM. PMID: 31092690; PMCID: PMC6672034.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    110. Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis. J Am Coll Cardiol. 2019 05 07; 73(17):2150-2162. Zheng KH, Tsimikas S, Pawade T, Kroon J, Jenkins WSA, Doris MK, White AC, Timmers NKLM, Hjortnaes J, Rogers MA, Aikawa E, Arsenault BJ, Witztum JL, Newby DE, Koschinsky ML, Fayad ZA, Stroes ESG, Boekholdt SM, Dweck MR. PMID: 31047003; PMCID: PMC6494952.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    111. Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography. CJC Open. 2019 May; 1(3):131-140. Després AA, Perrot N, Poulin A, Tastet L, Shen M, Chen HY, Bourgeois R, Trottier M, Tessier M, Guimond J, Nadeau M, Engert JC, Thériault S, Bossé Y, Witztum JL, Couture P, Mathieu P, Dweck MR, Tsimikas S, Thanassoulis G, Pibarot P, Clavel MA, Arsenault BJ. PMID: 32159096; PMCID: PMC7063623.
      View in: PubMed   Mentions: 21  
    112. In Search of Patients With Elevated Lp(a): Seek and Ye Shall Find. J Am Coll Cardiol. 2019 03 12; 73(9):1040-1042. Tsimikas S. PMID: 30846098.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    113. Lipid-Lowering Agents. Circ Res. 2019 02; 124(3):386-404. Hegele RA, Tsimikas S. PMID: 30702996.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    114. Potential Causality and Emerging Medical Therapies for Lipoprotein(a) and Its Associated Oxidized Phospholipids in Calcific Aortic Valve Stenosis. Circ Res. 2019 02; 124(3):405-415. Tsimikas S. PMID: 30702993; PMCID: PMC6361547.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    115. Lipoprotein(a) in Patients Undergoing Transcatheter Aortic Valve Replacement. Angiology. 2019 Apr; 70(4):332-336. Ma GS, Wilkinson MJ, Reeves RR, Yeang C, DeMaria AN, Cotter B, Patel M, Mahmud E, Tsimikas S. PMID: 30700108.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    116. Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids. Cardiovasc Res. 2019 01 01; 115(1):179-189. Yeang C, Hasanally D, Que X, Hung MY, Stamenkovic A, Chan D, Chaudhary R, Margulets V, Edel AL, Hoshijima M, Gu Y, Bradford W, Dalton N, Miu P, Cheung DY, Jassal DS, Pierce GN, Peterson KL, Kirshenbaum LA, Witztum JL, Tsimikas S, Ravandi A. PMID: 29850765; PMCID: PMC6302283.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    117. Integrated Assessment of the Clinical Performance of GalNAc3-Conjugated 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer Experience. Nucleic Acid Ther. 2019 02; 29(1):16-32. Crooke ST, Baker BF, Xia S, Yu RZ, Viney NJ, Wang Y, Tsimikas S, Geary RS. PMID: 30570431; PMCID: PMC6386089.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCellsCTClinical Trials
    118. A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 02; 60(2):436-445. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 30563909; PMCID: PMC6358287.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    119. RNA-targeted therapeutics for lipid disorders. Curr Opin Lipidol. 2018 12; 29(6):459-466. Tsimikas S. PMID: 30234555.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    120. Association of Mild to Moderate Aortic Valve Stenosis Progression With Higher Lipoprotein(a) and Oxidized Phospholipid Levels: Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2018 12 01; 3(12):1212-1217. Capoulade R, Yeang C, Chan KL, Pibarot P, Tsimikas S. PMID: 30476957; PMCID: PMC6583098.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    121. Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis. JACC Cardiovasc Imaging. 2019 10; 12(10):2015-2026. Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C. PMID: 30343086; PMCID: PMC6461528.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    122. Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials. Lancet. 2018 10 13; 392(10155):1311-1320. Willeit P, Ridker PM, Nestel PJ, Simes J, Tonkin AM, Pedersen TR, Schwartz GG, Olsson AG, Colhoun HM, Kronenberg F, Drechsler C, Wanner C, Mora S, Lesogor A, Tsimikas S. PMID: 30293769.
      View in: PubMed   Mentions: 135     Fields:    Translation:Humans
    123. Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 09; 561(7724):E43. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 30013121.
      View in: PubMed   Mentions: 4     Fields:    
    124. Relationship of lipoprotein-associated apolipoprotein C-III with lipid variables and coronary artery disease risk: The EPIC-Norfolk prospective population study. J Clin Lipidol. 2018 Nov - Dec; 12(6):1493-1501.e11. van Capelleveen JC, Lee SR, Verbeek R, Kastelein JJP, Wareham NJ, Stroes ESG, Hovingh GK, Khaw KT, Boekholdt SM, Witztum JL, Tsimikas S. PMID: 30249512; PMCID: PMC6970616.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    125. Relationship of lipoprotein(a) molar concentrations and mass according to lipoprotein(a) thresholds and apolipoprotein(a) isoform size. J Clin Lipidol. 2018 Sep - Oct; 12(5):1313-1323. Tsimikas S, Fazio S, Viney NJ, Xia S, Witztum JL, Marcovina SM. PMID: 30100157.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    126. Lipoprotein Apheresis Acutely Reverses Coronary Microvascular Dysfunction in Patients With Severe Hypercholesterolemia. JACC Cardiovasc Imaging. 2019 08; 12(8 Pt 1):1430-1440. Wu MD, Moccetti F, Brown E, Davidson BP, Atkinson T, Belcik JT, Giraud G, Duell PB, Fazio S, Tavori H, Tsimikas S, Lindner JR. PMID: 29909101; PMCID: PMC6458098.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    127. Oxidation-specific epitopes restrain bone formation. Nat Commun. 2018 06 06; 9(1):2193. Ambrogini E, Que X, Wang S, Yamaguchi F, Weinstein RS, Tsimikas S, Manolagas SC, Witztum JL, Jilka RL. PMID: 29875355; PMCID: PMC5990540.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    128. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 06; 558(7709):301-306. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 29875409; PMCID: PMC6033669.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    129. Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):E4680-E4689. Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, Tremblay MS, Glass CK. PMID: 29632203; PMCID: PMC5960280.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    130. In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes. J Lipid Res. 2018 05; 59(5):741-744. Tsimikas S. PMID: 29610122; PMCID: PMC5928428.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    131. Relationship between "LDL-C", estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide. J Clin Lipidol. 2018 May - Jun; 12(3):702-710. Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. PMID: 29574075.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    132. PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis. J Am Coll Cardiol. 2018 01 23; 71(3):321-335. Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S. PMID: 29348025; PMCID: PMC5995462.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    133. Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease. J Cardiovasc Transl Res. 2018 06; 11(3):221-229. Kothari H, Nguyen AT, Yang X, Hisada Y, Tsimikas S, Mackman N, Taylor A, McNamara CA. PMID: 29344841.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    134. NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis. J Am Coll Cardiol. 2018 01 16; 71(2):177-192. Tsimikas S, Fazio S, Ferdinand KC, Ginsberg HN, Koschinsky ML, Marcovina SM, Moriarty PM, Rader DJ, Remaley AT, Reyes-Soffer G, Santos RD, Thanassoulis G, Witztum JL, Danthi S, Olive M, Liu L. PMID: 29325642; PMCID: PMC5868960.
      View in: PubMed   Mentions: 126     Fields:    Translation:Humans
    135. Interleukin-1 genotypes modulate the long-term effect of lipoprotein(a) on cardiovascular events: The Ioannina Study. J Clin Lipidol. 2018 Mar - Apr; 12(2):338-347. Naka KK, Bechlioullis A, Marini A, Sionis D, Vakalis K, Triantis G, Wilkins L, Rogus J, Kornman KS, Witztum JL, Doucette-Stamm L, Michalis LK, Tsimikas S. PMID: 29310992.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    136. Plasma Proteomics for Epidemiology: Increasing Throughput With Standard-Flow Rates. Circ Cardiovasc Genet. 2017 Dec; 10(6). Yin X, Baig F, Haudebourg E, Blankley RT, Gandhi T, Müller S, Reiter L, Hinterwirth H, Pechlaner R, Tsimikas S, Santer P, Willeit J, Kiechl S, Witztum JL, Sullivan A, Mayr M. PMID: 29237681.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    137. The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in Humans. Nucleic Acid Ther. 2018 02; 28(1):10-22. Crooke ST, Baker BF, Pham NC, Hughes SG, Kwoh TJ, Cai D, Tsimikas S, Geary RS, Bhanot S. PMID: 29185862; PMCID: PMC5790433.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    138. Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)Rx and IONIS-APO(a)-LRx antisense oligonucleotide clinical trials. J Clin Lipidol. 2018 Jan - Feb; 12(1):122-129.e2. Marcovina SM, Viney NJ, Hughes SG, Xia S, Witztum JL, Tsimikas S. PMID: 29174389.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    139. Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up. Eur Heart J. 2017 Sep 01; 38(33):2547-2555. Hartikainen J, Hassinen I, Hedman A, Kivelä A, Saraste A, Knuuti J, Husso M, Mussalo H, Hedman M, Rissanen TT, Toivanen P, Heikura T, Witztum JL, Tsimikas S, Ylä-Herttuala S. PMID: 28903476; PMCID: PMC5837555.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCellsCTClinical Trials
    140. Threshold Effects of Circulating Angiopoietin-Like 3 Levels on Plasma Lipoproteins. J Clin Endocrinol Metab. 2017 09 01; 102(9):3340-3348. Fazio S, Minnier J, Shapiro MD, Tsimikas S, Tarugi P, Averna MR, Arca M, Tavori H. PMID: 28633452; PMCID: PMC5587068.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    141. Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis. JACC Basic Transl Sci. 2017 Jun; 2(3):229-240. Torzewski M, Ravandi A, Yeang C, Edel A, Bhindi R, Kath S, Twardowski L, Schmid J, Yang X, Franke UFW, Witztum JL, Tsimikas S. PMID: 29147686; PMCID: PMC5685511.
      View in: PubMed   Mentions: 38  
    142. Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease: The Copenhagen General Population Study. Arterioscler Thromb Vasc Biol. 2017 08; 37(8):1570-1578. Kamstrup PR, Hung MY, Witztum JL, Tsimikas S, Nordestgaard BG. PMID: 28572160; PMCID: PMC5551411.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    143. Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides. N Engl J Med. 2017 07 20; 377(3):222-232. Graham MJ, Lee RG, Brandt TA, Tai LJ, Fu W, Peralta R, Yu R, Hurh E, Paz E, McEvoy BW, Baker BF, Pham NC, Digenio A, Hughes SG, Geary RS, Witztum JL, Crooke RM, Tsimikas S. PMID: 28538111.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansAnimalsCTClinical Trials
    144. Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol. 2017 06; 37(6):1206-1212. van Capelleveen JC, Bernelot Moens SJ, Yang X, Kastelein JJP, Wareham NJ, Zwinderman AH, Stroes ESG, Witztum JL, Hovingh GK, Khaw KT, Boekholdt SM, Tsimikas S. PMID: 28473441; PMCID: PMC5484077.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    145. Relationship of Autoantibodies to MDA-LDL and ApoB-Immune Complexes to Sex, Ethnicity, Subclinical Atherosclerosis, and Cardiovascular Events. Arterioscler Thromb Vasc Biol. 2017 06; 37(6):1213-1221. Prasad A, Clopton P, Ayers C, Khera A, de Lemos JA, Witztum JL, Tsimikas S. PMID: 28473443; PMCID: PMC5500201.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    146. Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis. Lancet Diabetes Endocrinol. 2017 07; 5(7):524-533. Saleheen D, Haycock PC, Zhao W, Rasheed A, Taleb A, Imran A, Abbas S, Majeed F, Akhtar S, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Mallick NH, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Frossard P, Tsimikas S, Witztum JL, Marcovina S, Sandhu M, Rader DJ, Danesh J. PMID: 28408323; PMCID: PMC5483508.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    147. Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgRKT to the List. Circ Res. 2017 03 31; 120(7):1050-1052. Yeang C, Gordts PL, Tsimikas S. PMID: 28360338; PMCID: PMC5470738.
      View in: PubMed   Mentions: 7     Fields:    
    148. Lipoprotein(a) and incident type-2 diabetes: results from the prospective Bruneck study and a meta-analysis of published literature. Cardiovasc Diabetol. 2017 03 21; 16(1):38. Paige E, Masconi KL, Tsimikas S, Kronenberg F, Santer P, Weger S, Willeit J, Kiechl S, Willeit P. PMID: 28320383; PMCID: PMC5359972.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    149. Lipoprotein(a) Improves Cardiovascular Risk Prediction Based on Established Risk Algorithms. J Am Coll Cardiol. 2017 03 21; 69(11):1513-1515. Verbeek R, Sandhu MS, Hovingh GK, Sjouke B, Wareham NJ, Zwinderman AH, Kastelein JJP, Khaw KT, Tsimikas S, Boekholdt SM. PMID: 28302296.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    150. Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial. Atherosclerosis. 2017 05; 260:1-7. Capoulade R, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. PMID: 28319871.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    151. Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III. J Am Coll Cardiol. 2017 Feb 21; 69(7):789-800. Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum JL, Alexander VJ, Willeit J, Kiechl S, Mayr M. PMID: 28209220; PMCID: PMC5314136.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    152. Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis. J Biol Chem. 2017 03 31; 292(13):5378-5391. Lu J, Guo S, Xue X, Chen Q, Ge J, Zhuo Y, Zhong H, Chen B, Zhao M, Han W, Suzuki T, Zhu M, Xia L, Schneider C, Blackwell TS, Porter NA, Zheng L, Tsimikas S, Yin H. PMID: 28202546; PMCID: PMC5392682.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    153. A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies. J Am Coll Cardiol. 2017 Feb 14; 69(6):692-711. Tsimikas S. PMID: 28183512.
      View in: PubMed   Mentions: 290     Fields:    Translation:Humans
    154. Oxidized Phospholipids on Apolipoprotein B-100 and Recurrent Ischemic Events Following Stroke or Transient Ischemic Attack. J Am Coll Cardiol. 2017 Jan 17; 69(2):147-158. Byun YS, Yang X, Bao W, DeMicco D, Laskey R, Witztum JL, Tsimikas S, SPARCL Trial Investigators. PMID: 28081824.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    155. The Prevalence of Lipoprotein(a) Measurement and Degree of Elevation Among 2710 Patients With Calcific Aortic Valve Stenosis in an Academic Echocardiography Laboratory Setting. Angiology. 2017 Oct; 68(9):795-798. Wilkinson MJ, Ma GS, Yeang C, Ang L, Strachan M, DeMaria AN, Tsimikas S, Cotter B. PMID: 28068801.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    156. Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431 239 Patients. Arterioscler Thromb Vasc Biol. 2017 Mar; 37(3):580-588. Moriarty PM, Varvel SA, Gordts PL, McConnell JP, Tsimikas S. PMID: 28062489; PMCID: PMC5323356.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    157. LPA Gene, Ethnicity, and Cardiovascular Events. Circulation. 2017 Jan 17; 135(3):251-263. Lee SR, Prasad A, Choi YS, Xing C, Clopton P, Witztum JL, Tsimikas S. PMID: 27831500; PMCID: PMC5241172.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    158. Immune cell screening of a nanoparticle library improves atherosclerosis therapy. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6731-E6740. Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ. PMID: 27791119; PMCID: PMC5098679.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    159. Lipoprotein(a)-cholesterol levels estimated by vertical auto profile correlate poorly with Lp(a) mass in hyperlipidemic subjects: Implications for clinical practice interpretation of Lp(a)-mediated risk. J Clin Lipidol. 2016 Nov - Dec; 10(6):1389-1396. Yeang C, Clopton PC, Tsimikas S. PMID: 27919356; PMCID: PMC8545497.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    160. Prevalence of Elevated Lp(a) Mass Levels and Patient Thresholds in 532 359 Patients in the United States. Arterioscler Thromb Vasc Biol. 2016 11; 36(11):2239-2245. Varvel S, McConnell JP, Tsimikas S. PMID: 27659098.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    161. Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials. Lancet. 2016 11 05; 388(10057):2239-2253. Viney NJ, van Capelleveen JC, Geary RS, Xia S, Tami JA, Yu RZ, Marcovina SM, Hughes SG, Graham MJ, Crooke RM, Crooke ST, Witztum JL, Stroes ES, Tsimikas S. PMID: 27665230.
      View in: PubMed   Mentions: 237     Fields:    Translation:HumansCTClinical Trials
    162. Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans. Circulation. 2016 Aug 23; 134(8):611-24. van der Valk FM, Bekkering S, Kroon J, Yeang C, Van den Bossche J, van Buul JD, Ravandi A, Nederveen AJ, Verberne HJ, Scipione C, Nieuwdorp M, Joosten LA, Netea MG, Koschinsky ML, Witztum JL, Tsimikas S, Riksen NP, Stroes ES. PMID: 27496857; PMCID: PMC4995139.
      View in: PubMed   Mentions: 183     Fields:    Translation:HumansCellsCTClinical Trials
    163. The re-emergence of lipoprotein(a) in a broader clinical arena. Prog Cardiovasc Dis. 2016 Sep - Oct; 59(2):135-144. Tsimikas S. PMID: 27497506.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    164. Elevated Lp(a) and Abdominal Aortic Aneurysm. Angiology. 2017 02; 68(2):96-98. Alexandrou AT, Tsimikas S. PMID: 27207842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    165. Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction. J Thromb Thrombolysis. 2016 Jul; 42(1):61-76. DeFilippis AP, Chernyavskiy I, Amraotkar AR, Trainor PJ, Kothari S, Ismail I, Hargis CW, Korley FK, Leibundgut G, Tsimikas S, Rai SN, Bhatnagar A. PMID: 26510751; PMCID: PMC5403145.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    166. Lipoprotein(a) and oxidized phospholipids in calcific aortic valve stenosis. Curr Opin Cardiol. 2016 07; 31(4):440-50. Yeang C, Wilkinson MJ, Tsimikas S. PMID: 27205885; PMCID: PMC4956483.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    167. Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease. J Intern Med. 2016 11; 280(5):509-517. Nsaibia MJ, Mahmut A, Boulanger MC, Arsenault BJ, Bouchareb R, Simard S, Witztum JL, Clavel MA, Pibarot P, Bossé Y, Tsimikas S, Mathieu P. PMID: 27237700.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    168. In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models. JACC Cardiovasc Imaging. 2016 08; 9(8):950-61. Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ. PMID: 27236528; PMCID: PMC5589956.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    169. Long-term mipomersen treatment is associated with a reduction in cardiovascular events in patients with familial hypercholesterolemia. J Clin Lipidol. 2016 Jul-Aug; 10(4):1011-1021. Duell PB, Santos RD, Kirwan BA, Witztum JL, Tsimikas S, Kastelein JJP. PMID: 27578134.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    170. Acute and long-term effect of percutaneous coronary intervention on serially-measured oxidative, inflammatory, and coagulation biomarkers in patients with stable angina. J Thromb Thrombolysis. 2016 May; 41(4):569-80. Leibundgut G, Lee JH, Strauss BH, Segev A, Tsimikas S. PMID: 26964999; PMCID: PMC4811750.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    171. PCSK9 Association With Lipoprotein(a). Circ Res. 2016 06 24; 119(1):29-35. Tavori H, Christian D, Minnier J, Plubell D, Shapiro MD, Yeang C, Giunzioni I, Croyal M, Duell PB, Lambert G, Tsimikas S, Fazio S. PMID: 27121620; PMCID: PMC4920709.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    172. The role of lipoprotein(a) in progression of renal disease: Causality or reverse causality? J Diabetes Complications. 2016 07; 30(5):755-7. Yeang C, Tsimikas S. PMID: 27118508.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    173. Lipoprotein(a): novel target and emergence of novel therapies to lower cardiovascular disease risk. Curr Opin Endocrinol Diabetes Obes. 2016 Apr; 23(2):157-64. Tsimikas S. PMID: 26825471; PMCID: PMC5061509.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    174. Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a). J Clin Lipidol. 2016 May-Jun; 10(3):594-603. Yeang C, Hung MY, Byun YS, Clopton P, Yang X, Witztum JL, Tsimikas S. PMID: 27206947.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    175. JCL Roundtable: Should we treat elevations in Lp(a)? J Clin Lipidol. 2016 Mar-Apr; 10(2):215-24. Brown WV, Moriarty PM, Remaley AT, Tsimikas S. PMID: 27055952.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    176. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4):682-91. Harmon DB, Srikakulapu P, Kaplan JL, Oldham SN, McSkimming C, Garmey JC, Perry HM, Kirby JL, Prohaska TA, Gonen A, Hallowell P, Schirmer B, Tsimikas S, Taylor AM, Witztum JL, McNamara CA. PMID: 26868208; PMCID: PMC4808436.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    177. Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results. J Lipid Res. 2016 Apr; 57(4):706-13. Yang X, Lee SR, Choi YS, Alexander VJ, Digenio A, Yang Q, Miller YI, Witztum JL, Tsimikas S. PMID: 26848137; PMCID: PMC4808774.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    178. Experimental Animal Models Evaluating the Causal Role of Lipoprotein(a) in Atherosclerosis and Aortic Stenosis. Cardiovasc Drugs Ther. 2016 Feb; 30(1):75-85. Yeang C, Cotter B, Tsimikas S. PMID: 26780907.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    179. Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study. J Lipid Res. 2016 Apr; 57(4):697-705. Verbeek R, Boekholdt SM, Stoekenbroek RM, Hovingh GK, Witztum JL, Wareham NJ, Sandhu MS, Khaw KT, Tsimikas S. PMID: 26828068; PMCID: PMC4808778.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    180. Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans. J Lipid Res. 2016 Mar; 57(3):340-51. Graham MJ, Viney N, Crooke RM, Tsimikas S. PMID: 26538546; PMCID: PMC4767000.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    181. Mechanistic insights into Lp(a)-induced IL-8 expression: a role for oxidized phospholipid modification of apo(a). J Lipid Res. 2015 Dec; 56(12):2273-85. Scipione CA, Sayegh SE, Romagnuolo R, Tsimikas S, Marcovina SM, Boffa MB, Koschinsky ML. PMID: 26474593; PMCID: PMC4655984.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    182. Apolipoprotein C-III: From Pathophysiology to Pharmacology. Trends Pharmacol Sci. 2015 Oct; 36(10):675-687. Norata GD, Tsimikas S, Pirillo A, Catapano AL. PMID: 26435212.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimals
    183. Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis. J Am Coll Cardiol. 2015 Sep 15; 66(11):1236-1246. Capoulade R, Chan KL, Yeang C, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Mahmut A, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. PMID: 26361154.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    184. Invasive Cardiologists Are Exposed to Greater Left Sided Cranial Radiation: The BRAIN Study (Brain Radiation Exposure and Attenuation During Invasive Cardiology Procedures). JACC Cardiovasc Interv. 2015 Aug 17; 8(9):1197-1206. Reeves RR, Ang L, Bahadorani J, Naghi J, Dominguez A, Palakodeti V, Tsimikas S, Patel MP, Mahmud E. PMID: 26292583.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    185. Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study. Lancet. 2015 Oct 10; 386(10002):1472-83. Tsimikas S, Viney NJ, Hughes SG, Singleton W, Graham MJ, Baker BF, Burkey JL, Yang Q, Marcovina SM, Geary RS, Crooke RM, Witztum JL. PMID: 26210642.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansCellsCTClinical Trials
    186. B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis. Circ Res. 2015 Jul 17; 117(3):e28-39. Rosenfeld SM, Perry HM, Gonen A, Prohaska TA, Srikakulapu P, Grewal S, Das D, McSkimming C, Taylor AM, Tsimikas S, Bender TP, Witztum JL, McNamara CA. PMID: 26082558; PMCID: PMC4527334.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    187. Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-analysis of randomized controlled clinical trials in individuals without diabetes. Atherosclerosis. 2015 Aug; 241(2):409-18. Vallejo-Vaz AJ, Kondapally Seshasai SR, Kurogi K, Michishita I, Nozue T, Sugiyama S, Tsimikas S, Yoshida H, Ray KK. PMID: 26074315.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    188. 'LDL-C' = LDL-C + Lp(a)-C: implications of achieved ultra-low LDL-C levels in the proprotein convertase subtilisin/kexin type 9 era of potent LDL-C lowering. Curr Opin Lipidol. 2015 Jun; 26(3):169-78. Yeang C, Witztum JL, Tsimikas S. PMID: 25943842.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    189. HDL-C, ABCA1-mediated cholesterol efflux, and lipoprotein(a): insights into a potential novel physiologic role of lipoprotein(a). J Lipid Res. 2015 Jul; 56(7):1241-4. Yeang C, Tsimikas S. PMID: 26014961; PMCID: PMC4479328.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    190. Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study. Arterioscler Thromb Vasc Biol. 2015 Jul; 35(7):1704-11. Rao F, Schork AJ, Maihofer AX, Nievergelt CM, Marcovina SM, Miller ER, Witztum JL, O'Connor DT, Tsimikas S. PMID: 25953646; PMCID: PMC4483152.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    191. Retrieval of a detached transseptal sheath tip from a right pulmonary artery branch following catheter ablation. Catheter Cardiovasc Interv. 2015 Nov 15; 86(6):1131-5. Schricker AA, Feld GK, Tsimikas S. PMID: 25913843.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    192. Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial. J Am Coll Cardiol. 2015 Apr 07; 65(13):1286-1295. Byun YS, Lee JH, Arsenault BJ, Yang X, Bao W, DeMicco D, Laskey R, Witztum JL, Tsimikas S, TNT Trial Investigators. PMID: 25835440; PMCID: PMC4386070.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    193. Plasma Levels of Advanced Glycation End Products Are Related to the Clinical Presentation and Angiographic Severity of Symptomatic Lower Extremity Peripheral Arterial Disease. Int J Angiol. 2016 Mar; 25(1):44-53. Prasad A, Lane JR, Tsimikas S, Mahmud E, Khandrika S, Bekker P, Ilapakurti M, Nguyen D, Ravandi A, Israel T. PMID: 26900311; PMCID: PMC4758845.
      View in: PubMed   Mentions: 2  
    194. Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):689-99. Santos RD, Raal FJ, Catapano AL, Witztum JL, Steinhagen-Thiessen E, Tsimikas S. PMID: 25614280; PMCID: PMC4344404.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    195. Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc. 2015; 113:T5. Handa JT, Tagami M, Ebrahimi K, Leibundgut G, Janiak A, Witztum JL, Tsimikas S. PMID: 26538774; PMCID: PMC4601905.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    196. Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies. J Lipid Res. 2015 Feb; 56(2):440-8. Tsiantoulas D, Perkmann T, Afonyushkin T, Mangold A, Prohaska TA, Papac-Milicevic N, Millischer V, Bartel C, Hörkkö S, Boulanger CM, Tsimikas S, Fischer MB, Witztum JL, Lang IM, Binder CJ. PMID: 25525116; PMCID: PMC4306697.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    197. What is the ultimate test that lowering lipoprotein(a) is beneficial for cardiovascular disease and aortic stenosis? Curr Opin Lipidol. 2014 Dec; 25(6):423-30. Hung MY, Tsimikas S. PMID: 25340480.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    198. Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis. PLoS One. 2014; 9(11):e112483. Willeit P, Raschenberger J, Heydon EE, Tsimikas S, Haun M, Mayr A, Weger S, Witztum JL, Butterworth AS, Willeit J, Kronenberg F, Kiechl S. PMID: 25390655; PMCID: PMC4229188.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    199. Prevalence of coronary artery spasm after stent placement and its association with inflammation. Int J Cardiol. 2015 Jan 20; 179:252-5. Hung MJ, Hsu KH, Chang NC, Tsimikas S, Hung MY. PMID: 25464459.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    200. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1):229-36. Pechlaner R, Willeit P, Summerer M, Santer P, Egger G, Kronenberg F, Demetz E, Weiss G, Tsimikas S, Witztum JL, Willeit K, Iglseder B, Paulweber B, Kedenko L, Haun M, Meisinger C, Gieger C, Müller-Nurasyid M, Peters A, Willeit J, Kiechl S. PMID: 25359861; PMCID: PMC4317265.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    201. Imaging of oxidation-specific epitopes with targeted nanoparticles to detect high-risk atherosclerotic lesions: progress and future directions. J Cardiovasc Transl Res. 2014 Nov; 7(8):719-36. Briley-Saebo K, Yeang C, Witztum JL, Tsimikas S. PMID: 25297940; PMCID: PMC4233166.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    202. Lipoprotein apheresis and acute reduction of arterial inflammation: FDG-PET as an imaging biomarker of nonpharmacological effects on the vessel wall. J Am Coll Cardiol. 2014 Oct 07; 64(14):1427-9. Tsimikas S. PMID: 25277611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    203. Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study. J Am Coll Cardiol. 2014 Sep 02; 64(9):851-60. Willeit P, Kiechl S, Kronenberg F, Witztum JL, Santer P, Mayr M, Xu Q, Mayr A, Willeit J, Tsimikas S. PMID: 25169167.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    204. Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine. J Lipid Res. 2014 Oct; 55(10):2137-55. Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. PMID: 25143462; PMCID: PMC4174006.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    205. The severe hypercholesterolemia phenotype: clinical diagnosis, management, and emerging therapies. J Am Coll Cardiol. 2014 May 20; 63(19):1935-47. Sniderman AD, Tsimikas S, Fazio S. PMID: 24632267.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    206. Manganese G8 dendrimers targeted to oxidation-specific epitopes: in vivo MR imaging of atherosclerosis. J Magn Reson Imaging. 2015 Mar; 41(3):797-805. Nguyen TH, Bryant H, Shapsa A, Street H, Mani V, Fayad ZA, Frank JA, Tsimikas S, Briley-Saebo KC. PMID: 24610640; PMCID: PMC4160426.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    207. Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans. J Am Coll Cardiol. 2014 May 20; 63(19):1961-71. Ravandi A, Leibundgut G, Hung MY, Patel M, Hutchins PM, Murphy RC, Prasad A, Mahmud E, Miller YI, Dennis EA, Witztum JL, Tsimikas S. PMID: 24613321; PMCID: PMC4629781.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    208. Highlights of the year in JACC 2013. J Am Coll Cardiol. 2014 Feb 18; 63(6):570-602. DeMaria AN, Adler ED, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall JL, Hlatky MA, Lew WY, Lima JA, Mahmud E, Maisel AS, Narayan SM, Nissen SE, Sahn DJ, Tsimikas S. PMID: 24524815.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    209. Pro-inflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a). J Am Coll Cardiol. 2014 May 06; 63(17):1724-34. Tsimikas S, Duff GW, Berger PB, Rogus J, Huttner K, Clopton P, Brilakis E, Kornman KS, Witztum JL. PMID: 24530664; PMCID: PMC4008715.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    210. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. PLoS One. 2013; 8(12):e83145. Choi SH, Yin H, Ravandi A, Armando A, Dumlao D, Kim J, Almazan F, Taylor AM, McNamara CA, Tsimikas S, Dennis EA, Witztum JL, Miller YI. PMID: 24376657; PMCID: PMC3871536.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    211. New therapeutic targets for calcific aortic valve stenosis: the lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis. J Am Coll Cardiol. 2014 Feb 11; 63(5):478-80. Hung MY, Witztum JL, Tsimikas S. PMID: 24161316; PMCID: PMC5928500.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    212. Lipoprotein(a) for risk assessment in patients with established coronary artery disease. J Am Coll Cardiol. 2014 Feb 18; 63(6):520-7. O'Donoghue ML, Morrow DA, Tsimikas S, Sloan S, Ren AF, Hoffman EB, Desai NR, Solomon SD, Domanski M, Arai K, Chiuve SE, Cannon CP, Sacks FM, Sabatine MS. PMID: 24161323; PMCID: PMC3945105.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansPHPublic Health
    213. Helix-loop-helix factor inhibitor of differentiation 3 regulates interleukin-5 expression and B-1a B cell proliferation. Arterioscler Thromb Vasc Biol. 2013 Dec; 33(12):2771-9. Perry HM, Oldham SN, Fahl SP, Que X, Gonen A, Harmon DB, Tsimikas S, Witztum JL, Bender TP, McNamara CA. PMID: 24115031; PMCID: PMC4003558.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    214. The association between circulating lipoprotein(a) and type 2 diabetes: is it causal? Diabetes. 2014 Jan; 63(1):332-342. Ye Z, Haycock PC, Gurdasani D, Pomilla C, Boekholdt SM, Tsimikas S, Khaw KT, Wareham NJ, Sandhu MS, Forouhi NG. PMID: 24089516; PMCID: PMC4246060.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    215. Oxidation-specific epitopes as targets for biotheranostic applications in humans: biomarkers, molecular imaging and therapeutics. Curr Opin Lipidol. 2013 Oct; 24(5):426-37. Miller YI, Tsimikas S. PMID: 23995232; PMCID: PMC4085330.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    216. Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol. 2013 Nov 19; 62(21):1966-1976. Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EPA, Li M, Leusink M, Trompet S, Verschuren JJW, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, van 't Hooft F, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Mateo Leach I, Breitling LP, Brenner H, Thiery J, Dallmeier D, Franco-Cereceda A, Boer JMA, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day INM, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der Zee AH, Khaw KT, Keating BJ, van der Harst P, Price JF, Mehta SR, Yusuf S, Witteman JCM, Franco OH, Jukema JW, de Knijff P, Tybjaerg-Hansen A, Rader DJ, Farrall M, Samani NJ, Kivimaki M, Fox KAA, Humphries SE, Anderson JL, Boekholdt SM, Palmer TM, Eriksson P, Paré G, Hingorani AD, Sabatine MS, Mallat Z, Casas JP, Talmud PJ. PMID: 23916927; PMCID: PMC3826105.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    217. Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res. 2013 Oct; 54(10):2815-30. Leibundgut G, Scipione C, Yin H, Schneider M, Boffa MB, Green S, Yang X, Dennis E, Witztum JL, Koschinsky ML, Tsimikas S. PMID: 23828779; PMCID: PMC3770094.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    218. Tracking oxidatively stressed cardiac stem cells with molecular imaging: "insights" into fate, viability, and function. JACC Cardiovasc Imaging. 2013 Jul; 6(7):803-5. Tsimikas S. PMID: 23845575.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    219. IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitope. PLoS One. 2013; 8(6):e65203. Que X, Widhopf GF, Amir S, Hartvigsen K, Hansen LF, Woelkers D, Tsimikas S, Binder CJ, Kipps TJ, Witztum JL. PMID: 23840319; PMCID: PMC3688726.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    220. Statin therapy and secretory phospholipase A₂ in children with heterozygous familial hypercholesterolemia. Atherosclerosis. 2013 Aug; 229(2):404-7. Braamskamp MJ, Tsimikas S, Wiegman A, Kastelein JJ, Hutten BA. PMID: 23880195.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    221. MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res. 2013 Jul; 54(7):1877-83. Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI. PMID: 23667177; PMCID: PMC3679389.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    222. Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis. Curr Opin Pharmacol. 2013 Apr; 13(2):168-79. Leibundgut G, Witztum JL, Tsimikas S. PMID: 23541680; PMCID: PMC3844667.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    223. Oxidation-specific biomarkers and risk of peripheral artery disease. J Am Coll Cardiol. 2013 May 28; 61(21):2169-79. Bertoia ML, Pai JK, Lee JH, Taleb A, Joosten MM, Mittleman MA, Yang X, Witztum JL, Rimm EB, Tsimikas S, Mukamal KJ. PMID: 23541965; PMCID: PMC3756816.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    224. Highlights of the year in JACC 2012. J Am Coll Cardiol. 2013 Jan 22; 61(3):357-85. DeMaria AN, Bax JJ, Feld GK, Greenberg BH, Hall JL, Hlatky MA, Lew WY, Lima JA, Mahmud E, Maisel AS, Narayan SM, Nissen SE, Sahn DJ, Tsimikas S. PMID: 23328613; PMCID: PMC3760511.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    225. Adaptive immunity in atherogenesis: new insights and therapeutic approaches. J Clin Invest. 2013 Jan; 123(1):27-36. Lichtman AH, Binder CJ, Tsimikas S, Witztum JL. PMID: 23281407; PMCID: PMC3533280.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    226. Emerging therapeutic agents to lower lipoprotein (a) levels. Curr Opin Lipidol. 2012 Dec; 23(6):560-8. Kolski B, Tsimikas S. PMID: 23041907.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    227. Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia. Atherosclerosis. 2013 Jan; 226(1):161-4. Yoshida H, Shoda T, Yanai H, Ikewaki K, Kurata H, Ito K, Furutani N, Tada N, Witztum JL, Tsimikas S. PMID: 23174369.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    228. Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events. J Am Coll Cardiol. 2012 Nov 20; 60(21):2218-29. Tsimikas S, Willeit P, Willeit J, Santer P, Mayr M, Xu Q, Mayr A, Witztum JL, Kiechl S. PMID: 23122790.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    229. Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12):3058-65. Gurdasani D, Sjouke B, Tsimikas S, Hovingh GK, Luben RN, Wainwright NW, Pomilla C, Wareham NJ, Khaw KT, Boekholdt SM, Sandhu MS. PMID: 23065826; PMCID: PMC4210842.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    230. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52. Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. PMID: 23021221; PMCID: PMC3464914.
      View in: PubMed   Mentions: 285     Fields:    Translation:AnimalsCells
    231. Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations. Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12):3066-75. Holleboom AG, Daniil G, Fu X, Zhang R, Hovingh GK, Schimmel AW, Kastelein JJ, Stroes ES, Witztum JL, Hutten BA, Tsimikas S, Hazen SL, Chroni A, Kuivenhoven JA. PMID: 23023370; PMCID: PMC3610418.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    232. Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions. J Lipid Res. 2012 Dec; 53(12):2773-90. van Dijk RA, Kolodgie F, Ravandi A, Leibundgut G, Hu PP, Prasad A, Mahmud E, Dennis E, Curtiss LK, Witztum JL, Wasserman BA, Otsuka F, Virmani R, Tsimikas S. PMID: 22969153; PMCID: PMC3494262.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    233. Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol. 2012 Aug 21; 60(8):716-21. Tsimikas S, Hall JL. PMID: 22898069.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimals
    234. Regression of inflammation in atherosclerosis by the LXR agonist R211945: a noninvasive assessment and comparison with atorvastatin. JACC Cardiovasc Imaging. 2012 Aug; 5(8):819-28. Vucic E, Calcagno C, Dickson SD, Rudd JH, Hayashi K, Bucerius J, Moshier E, Mounessa JS, Roytman M, Moon MJ, Lin J, Ramachandran S, Tanimoto T, Brown K, Kotsuma M, Tsimikas S, Fisher EA, Nicolay K, Fuster V, Fayad ZA. PMID: 22897996; PMCID: PMC3600612.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    235. Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis. J Am Coll Cardiol. 2012 Jul 10; 60(2):112-9. Purushothaman KR, Purushothaman M, Levy AP, Lento PA, Evrard S, Kovacic JC, Briley-Saebo KC, Tsimikas S, Witztum JL, Krishnan P, Kini A, Fayad ZA, Fuster V, Sharma SK, Moreno PR. PMID: 22766337.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    236. Advanced glycation end products and diabetic cardiovascular disease. Cardiol Rev. 2012 Jul-Aug; 20(4):177-83. Prasad A, Bekker P, Tsimikas S. PMID: 22314141.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    237. Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia. J Lipid Res. 2012 Aug; 53(8):1670-8. Arai K, Orsoni A, Mallat Z, Tedgui A, Witztum JL, Bruckert E, Tselepis AD, Chapman MJ, Tsimikas S. PMID: 22628616; PMCID: PMC3540845.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    238. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb). 2012 Jun; 4(6):595-605. Olson ES, Whitney MA, Friedman B, Aguilera TA, Crisp JL, Baik FM, Jiang T, Baird SM, Tsimikas S, Tsien RY, Nguyen QT. PMID: 22534729; PMCID: PMC3689578.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    239. Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction. J Am Coll Cardiol. 2012 Apr 17; 59(16):1426-37. Leibundgut G, Arai K, Orsoni A, Yin H, Scipione C, Miller ER, Koschinsky ML, Chapman MJ, Witztum JL, Tsimikas S. PMID: 22497821; PMCID: PMC3333481.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    240. Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease. J Lipid Res. 2012 Jul; 53(7):1316-26. Amir S, Hartvigsen K, Gonen A, Leibundgut G, Que X, Jensen-Jarolim E, Wagner O, Tsimikas S, Witztum JL, Binder CJ. PMID: 22508944; PMCID: PMC3371243.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    241. Lipoprotein oxidation biomarkers for cardiovascular risk: what does the future hold? Expert Rev Cardiovasc Ther. 2012 Apr; 10(4):399-402. Taleb A, Tsimikas S. PMID: 22458571.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    242. The clinical emergence of optical coherence tomography: defining a role in intravascular imaging. J Am Coll Cardiol. 2012 Mar 20; 59(12):1090-2. Tsimikas S, DeMaria AN. PMID: 22421302.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    243. Effect of an oral astaxanthin prodrug (CDX-085) on lipoprotein levels and progression of atherosclerosis in LDLR(-/-) and ApoE(-/-) mice. Atherosclerosis. 2012 May; 222(1):99-105. Ryu SK, King TJ, Fujioka K, Pattison J, Pashkow FJ, Tsimikas S. PMID: 22406426.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    244. In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes. J Am Coll Cardiol. 2012 Feb 07; 59(6):616-26. Briley-Saebo KC, Nguyen TH, Saeboe AM, Cho YS, Ryu SK, Volkova ER, Volkava E, Dickson S, Leibundgut G, Wiesner P, Weisner P, Green S, Casanada F, Miller YI, Shaw W, Witztum JL, Fayad ZA, Tsimikas S. PMID: 22300697; PMCID: PMC3333483.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    245. Highlights of the Year in JACC 2011. J Am Coll Cardiol. 2012 Jan 31; 59(5):503-37. Demaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 22281255.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    246. Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes. Circulation. 2012 Feb 14; 125(6):757-66. Ryu SK, Mallat Z, Benessiano J, Tedgui A, Olsson AG, Bao W, Schwartz GG, Tsimikas S, Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering (MIRACL) Trial Investigators. PMID: 22230483.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    247. In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish. J Clin Invest. 2011 Dec; 121(12):4861-9. Fang L, Green SR, Baek JS, Lee SH, Ellett F, Deer E, Lieschke GJ, Witztum JL, Tsimikas S, Miller YI. PMID: 22105168; PMCID: PMC3225997.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    248. The role of oxidized phospholipids, lipoprotein (a) and biomarkers of oxidized lipoproteins in chronically occluded coronary arteries in sudden cardiac death and following successful percutaneous revascularization. Cardiovasc Revasc Med. 2012 Jan-Feb; 13(1):11-9. Fefer P, Tsimikas S, Segev A, Sparkes J, Otsuka F, Otsuma F, Kolodgie F, Virmani R, Juliano J, Charron T, Strauss BH. PMID: 22079685.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    249. B-cell aortic homing and atheroprotection depend on Id3. Circ Res. 2012 Jan 06; 110(1):e1-12. Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, McNamara CA. PMID: 22034493; PMCID: PMC3253259.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    250. Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression. J Am Coll Cardiol. 2011 Oct 11; 58(16):1715-27. Tsimikas S, Miyanohara A, Hartvigsen K, Merki E, Shaw PX, Chou MY, Pattison J, Torzewski M, Sollors J, Friedmann T, Lai NC, Hammond HK, Getz GS, Reardon CA, Li AC, Banka CL, Witztum JL. PMID: 21982317; PMCID: PMC3230644.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    251. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011 Oct 05; 478(7367):76-81. Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. PMID: 21979047; PMCID: PMC4826616.
      View in: PubMed   Mentions: 260     Fields:    Translation:HumansAnimalsCells
    252. Oxidized phospholipids on apoB-100-containing lipoproteins: a biomarker predicting cardiovascular disease and cardiovascular events. Biomark Med. 2011 Oct; 5(5):673-94. Taleb A, Witztum JL, Tsimikas S. PMID: 22003918; PMCID: PMC3230643.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    253. Pioglitazone modulates vascular inflammation in atherosclerotic rabbits noninvasive assessment with FDG-PET-CT and dynamic contrast-enhanced MR imaging. JACC Cardiovasc Imaging. 2011 Oct; 4(10):1100-9. Vucic E, Dickson SD, Calcagno C, Rudd JH, Moshier E, Hayashi K, Mounessa JS, Roytman M, Moon MJ, Lin J, Tsimikas S, Fisher EA, Nicolay K, Fuster V, Fayad ZA. PMID: 21999870; PMCID: PMC3253377.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    254. Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists. J Clin Lipidol. 2011 Sep-Oct; 5(5):338-67. Davidson MH, Ballantyne CM, Jacobson TA, Bittner VA, Braun LT, Brown AS, Brown WV, Cromwell WC, Goldberg RB, McKenney JM, Remaley AT, Sniderman AD, Toth PP, Tsimikas S, Ziajka PE, Maki KC, Dicklin MR. PMID: 21981835.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    255. OxPL/apoB, lipoprotein(a) and OxLDL biomarkers and cardiovascular disease in chronic hemodialysis patients. J Nephrol. 2011 Sep-Oct; 24(5):581-8. Bossola M, Tazza L, Luciani G, Tortorelli A, Tsimikas S. PMID: 21404224.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    256. Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. J Lipid Res. 2011 Oct; 52(10):1829-36. Ravandi A, Boekholdt SM, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Tsimikas S. PMID: 21821825; PMCID: PMC3173004.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    257. Renal artery plaque composition is associated with changes in renal frame count following renal artery stenting. J Invasive Cardiol. 2011 Jun; 23(6):227-31. Prasad A, Ilapakurti M, Hu P, Zafar N, Palakodeti V, Tsimikas S, Mahmud E. PMID: 21646647.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    258. Successful treatment of in-stent restenosis of a covered stent graft with a paclitaxel-eluting stent. J Cardiol Cases. 2011 Aug; 4(1):e13-e15. Thani KB, Bennett WE, Ravandi A, Tsimikas S. PMID: 30532863; PMCID: PMC6265220.
      View in: PubMed   Mentions:
    259. Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice. J Am Coll Cardiol. 2011 Apr 12; 57(15):1611-21. Merki E, Graham M, Taleb A, Leibundgut G, Yang X, Miller ER, Fu W, Mullick AE, Lee R, Willeit P, Crooke RM, Witztum JL, Tsimikas S. PMID: 21474042.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    260. Highlights of the year in JACC 2010. J Am Coll Cardiol. 2011 Jan 25; 57(4):480-514. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 21251590.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    261. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res. 2011 Jan 21; 108(2):235-48. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. PMID: 21252151; PMCID: PMC3075542.
      View in: PubMed   Mentions: 301     Fields:    Translation:HumansAnimalsCells
    262. Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease. Curr Pharm Des. 2011; 17(1):27-37. Tsimikas S, Miller YI. PMID: 21226665.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    263. Imaging of Oxidation-Specific Epitopes in Atherosclerosis and Macrophage-Rich Vulnerable Plaques. Curr Cardiovasc Imaging Rep. 2011 Feb; 4(1):4-16. Briley-Saebo KC, Cho YS, Tsimikas S. PMID: 21297859; PMCID: PMC3018294.
      View in: PubMed   Mentions: 12  
    264. Targeted iron oxide particles for in vivo magnetic resonance detection of atherosclerotic lesions with antibodies directed to oxidation-specific epitopes. J Am Coll Cardiol. 2011 Jan 18; 57(3):337-47. Briley-Saebo KC, Cho YS, Shaw PX, Ryu SK, Mani V, Dickson S, Izadmehr E, Green S, Fayad ZA, Tsimikas S. PMID: 21106318; PMCID: PMC3095034.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    265. Lipoprotein-associated phospholipase A2 mass and activity in children with heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Clin Lipidol. 2011 Jan-Feb; 5(1):50-6. Ryu SK, Hutten BA, Vissers MN, Wiegman A, Kastelein JJ, Tsimikas S. PMID: 21262507.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    266. Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab. 2010 Nov 03; 12(5):467-82. Seimon TA, Nadolski MJ, Liao X, Magallon J, Nguyen M, Feric NT, Koschinsky ML, Harkewicz R, Witztum JL, Tsimikas S, Golenbock D, Moore KJ, Tabas I. PMID: 21035758; PMCID: PMC2991104.
      View in: PubMed   Mentions: 206     Fields:    Translation:AnimalsCells
    267. Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol. 2010 Sep 14; 56(12):946-55. Tsimikas S, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Sandhu MS, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Boekholdt SM. PMID: 20828647.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    268. Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet. J Lipid Res. 2010 Nov; 51(11):3324-30. Faghihnia N, Tsimikas S, Miller ER, Witztum JL, Krauss RM. PMID: 20713651; PMCID: PMC2952573.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    269. Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation. J Biol Chem. 2010 Oct 15; 285(42):32343-51. Fang L, Harkewicz R, Hartvigsen K, Wiesner P, Choi SH, Almazan F, Pattison J, Deer E, Sayaphupha T, Dennis EA, Witztum JL, Tsimikas S, Miller YI. PMID: 20710028; PMCID: PMC2952235.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    270. Lipoprotein(a) accelerates atherosclerosis in uremic mice. J Lipid Res. 2010 Oct; 51(10):2967-75. Pedersen TX, McCormick SP, Tsimikas S, Bro S, Nielsen LB. PMID: 20584868; PMCID: PMC2936745.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    271. Clinical Trial Report: The Presence and Rupture of Vulnerable Plaques in the Peripheral Circulation. Curr Cardiovasc Imaging Rep. 2010 Aug; 3(4):187-189. Prasad A, Tsimikas S. PMID: 20676192; PMCID: PMC2895890.
      View in: PubMed   Mentions: 1  
    272. Post-thienopyridine platelet response, cardiovascular outcomes, and personalized therapy: En attendant Godot. JACC Cardiovasc Interv. 2010 Jun; 3(6):657-9. Tsimikas S, Leibundgut G. PMID: 20630459.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    273. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium. Am J Cardiol. 2010 Feb 15; 105(4):459-66. Ahmadi N, Tsimikas S, Hajsadeghi F, Saeed A, Nabavi V, Bevinal MA, Kadakia J, Flores F, Ebrahimi R, Budoff MJ. PMID: 20152239.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    274. Highlights of the Year in JACC 2009. J Am Coll Cardiol. 2010 Jan 26; 55(4):380-407. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S. PMID: 20117446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    275. Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis. Subcell Biochem. 2010; 51:229-51. Miller YI, Choi SH, Fang L, Tsimikas S. PMID: 20213546.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    276. The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles. Atherosclerosis. 2010 Apr; 209(2):498-503. Arai K, Luke MM, Koschinsky ML, Miller ER, Pullinger CR, Witztum JL, Kane JP, Tsimikas S. PMID: 19880117.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    277. High-dose statins prior to percutaneous coronary intervention: a paradigm shift to influence clinical outcomes in the cardiac catheterization laboratory. J Am Coll Cardiol. 2009 Dec 01; 54(23):2164-6. Tsimikas S. PMID: 19775848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    278. Spontaneous recanalization of a completely occluded saphenous vein graft two months following acute myocardial infarction with persistent one year patency. J Thromb Thrombolysis. 2009 Jul; 28(1):101-5. Hu PP, Peterson KL, Tsimikas S. PMID: 19396586; PMCID: PMC2694324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    279. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial. Prev Med. 2009 Aug-Sep; 49(2-3):101-7. Budoff MJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S. PMID: 19573556.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    280. Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial. J Am Coll Cardiol. 2009 Jun 09; 53(23):2186-96. Fraley AE, Schwartz GG, Olsson AG, Kinlay S, Szarek M, Rifai N, Libby P, Ganz P, Witztum JL, Tsimikas S, MIRACL Study Investigators. PMID: 19497447.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    281. Estrogen-eluting stents. J Cardiovasc Transl Res. 2009 Sep; 2(3):240-4. Ryu SK, Mahmud E, Tsimikas S. PMID: 19654888; PMCID: PMC2719737.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    282. Relationship of oxidized phospholipids on apolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study. Circulation. 2009 Apr 07; 119(13):1711-9. Tsimikas S, Clopton P, Brilakis ES, Marcovina SM, Khera A, Miller ER, de Lemos JA, Witztum JL. PMID: 19307470; PMCID: PMC2782388.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    283. Molecular imaging of matrix metalloproteinase expression in atherosclerotic plaques of mice deficient in apolipoprotein e or low-density-lipoprotein receptor. J Nucl Med. 2009 Apr; 50(4):612-7. Ohshima S, Petrov A, Fujimoto S, Zhou J, Azure M, Edwards DS, Murohara T, Narula N, Tsimikas S, Narula J. PMID: 19289429.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    284. Highlights of the Year in JACC 2008. J Am Coll Cardiol. 2009 Jan 27; 53(4):373-98. DeMaria AN, Ben-Yehuda O, Bax JJ, Feld GK, Greenberg BH, Lew WY, Lima JA, Maisel AS, Narayan SM, Sahn DJ, Tsimikas S. PMID: 19161890.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    285. The role of innate immunity in atherogenesis. J Lipid Res. 2009 Apr; 50 Suppl:S388-93. Hartvigsen K, Chou MY, Hansen LF, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. PMID: 19106070; PMCID: PMC2674727.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    286. The role of oxidized phospholipids in atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S207-12. Berliner JA, Leitinger N, Tsimikas S. PMID: 19059906; PMCID: PMC2674746.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    287. Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study. Eur Heart J. 2009 Jan; 30(1):107-15. Tsimikas S, Willeit J, Knoflach M, Mayr M, Egger G, Notdurfter M, Witztum JL, Wiedermann CJ, Xu Q, Kiechl S. PMID: 19019993.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    288. Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population. Atherosclerosis. 2009 Jul; 205(1):261-5. Kiechl S, Lee T, Santer P, Thompson G, Tsimikas S, Egger G, Holt DW, Willeit J, Xu Q, Mayr M. PMID: 19100547.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    289. Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel. J Am Coll Cardiol. 2008 Sep 23; 52(13):1052-9. Ang L, Palakodeti V, Khalid A, Tsimikas S, Idrees Z, Tran P, Clopton P, Zafar N, Bromberg-Marin G, Keramati S, Mahmud E. PMID: 18848137.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    290. The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity. Curr Opin Lipidol. 2008 Aug; 19(4):369-77. Tsimikas S, Witztum JL. PMID: 18607184.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    291. Candidate biomarkers for the detection of coronary plaque destabilization and rupture. Curr Atheroscler Rep. 2008 Aug; 10(4):309-17. Prasad A, Tsimikas S. PMID: 18618976.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    292. Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice. Circulation. 2008 Aug 12; 118(7):743-53. Merki E, Graham MJ, Mullick AE, Miller ER, Crooke RM, Pitas RE, Witztum JL, Tsimikas S. PMID: 18663084.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    293. Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study. J Am Coll Cardiol. 2008 Jul 01; 52(1):24-32. Choi SH, Chae A, Miller E, Messig M, Ntanios F, DeMaria AN, Nissen SE, Witztum JL, Tsimikas S. PMID: 18582631.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    294. A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res. 2008 Oct; 49(10):2230-9. Bergmark C, Dewan A, Orsoni A, Merki E, Miller ER, Shin MJ, Binder CJ, Hörkkö S, Krauss RM, Chapman MJ, Witztum JL, Tsimikas S. PMID: 18594118.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCells
    295. The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents. J Am Coll Cardiol. 2008 Jun 10; 51(23):2228-9. Choi SH, Prasad A, Tsimikas S. PMID: 18534268.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    296. Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes. Circulation. 2008 Jun 24; 117(25):3206-15. Briley-Saebo KC, Shaw PX, Mulder WJ, Choi SH, Vucic E, Aguinaldo JG, Witztum JL, Fuster V, Tsimikas S, Fayad ZA. PMID: 18541740; PMCID: PMC4492476.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    297. Renal frame count and renal blush grade: quantitative measures that predict the success of renal stenting in hypertensive patients with renal artery stenosis. JACC Cardiovasc Interv. 2008 Jun; 1(3):286-92. Mahmud E, Smith TW, Palakodeti V, Zaidi O, Ang L, Mitchell CR, Zafar N, Bromberg-Marin G, Keramati S, Tsimikas S. PMID: 19463314.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    298. In vivo markers of oxidative stress and therapeutic interventions. Am J Cardiol. 2008 May 22; 101(10A):34D-42D. Tsimikas S. PMID: 18474272.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    299. Recent advances in hemodynamics: noncoronary applications of a pressure sensor angioplasty guidewire. Catheter Cardiovasc Interv. 2008 May 01; 71(6):748-58. Cavendish JJ, Carter LI, Tsimikas S. PMID: 18324696.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    300. The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. J Am Coll Cardiol. 2008 Apr 29; 51(17):1653-62. Ky B, Burke A, Tsimikas S, Wolfe ML, Tadesse MG, Szapary PO, Witztum JL, FitzGerald GA, Rader DJ. PMID: 18436117.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCTClinical Trials
    301. Highlights of the year in JACC 2007. J Am Coll Cardiol. 2008 Jan 29; 51(4):490-512. DeMaria AN, Bax JJ, Ben-Yehuda O, Clopton P, Feld GK, Ginsburg GS, Greenberg BH, Knoke JD, Lew WY, Lima JA, Maisel AS, Narayan SM, Narula J, Sahn DJ, Tsimikas S. PMID: 18222362.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    302. Oxidized low-density lipoprotein biomarkers in patients with end-stage renal failure: acute effects of hemodialysis. Blood Purif. 2007; 25(5-6):457-65. Bossola M, Tazza L, Merki E, Giungi S, Luciani G, Miller ER, Lin EB, Tortorelli A, Tsimikas S. PMID: 18075247.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    303. Antibodies to oxidized low density lipoprotein: epidemiological studies and potential clinical applications in cardiovascular disease. Minerva Cardioangiol. 2007 Dec; 55(6):821-37. Gounopoulos P, Merki E, Hansen LF, Choi SH, Tsimikas S. PMID: 18091649.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    304. New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease. Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2094-9. Tsimikas S, Tsironis LD, Tselepis AD. PMID: 17626905.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    305. Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1788-95. Kiechl S, Willeit J, Mayr M, Viehweider B, Oberhollenzer M, Kronenberg F, Wiedermann CJ, Oberthaler S, Xu Q, Witztum JL, Tsimikas S. PMID: 17541022.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansPHPublic Health
    306. Elevated plasma fibrinogen level predicts suboptimal response to therapy with both single- and double-bolus eptifibatide during percutaneous coronary intervention. J Am Coll Cardiol. 2007 Jun 05; 49(22):2163-71. Mahmud E, Cavendish JJ, Tsimikas S, Ang L, Nguyen C, Bromberg-Marin G, Schnyder G, Keramati S, Palakodeti V, Penny WF, DeMaria AN. PMID: 17543636.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    307. Spontaneous multivessel coronary vasospasm leading to cardiogenic shock. J Invasive Cardiol. 2007 Apr; 19(4):E85-8. Bromberg-Marin G, Mahmud E, Tsimikas S. PMID: 17404410.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    308. Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus. Catheter Cardiovasc Interv. 2007 Feb 15; 69(3):362-8. Bromberg-Marin G, Tsimikas S, Mahmud E. PMID: 17200960.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    309. Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):850-7. Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ. PMID: 17255533.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    310. Emerging approaches for imaging vulnerable plaques in patients. Curr Opin Biotechnol. 2007 Feb; 18(1):73-82. Choi SH, Chae A, Chen CH, Merki E, Shaw PX, Tsimikas S. PMID: 17234398.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    311. Highlights of the Year in JACC 2006. J Am Coll Cardiol. 2007 Jan 30; 49(4):509-27. DeMaria AN, Ben-Yehuda O, Feld GK, Ginsburg GS, Greenberg BH, Lew WY, Lima JA, Maisel AS, Narula J, Sahn DJ, Tsimikas S. PMID: 17258099.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    312. Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events. J Lipid Res. 2007 Feb; 48(2):425-33. Tsimikas S, Brilakis ES, Lennon RJ, Miller ER, Witztum JL, McConnell JP, Kornman KS, Berger PB. PMID: 17093289.
      View in: PubMed   Mentions: 117     Fields:    Translation:Humans
    313. Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):175-81. Tsimikas S, Aikawa M, Miller FJ, Miller ER, Torzewski M, Lentz SR, Bergmark C, Heistad DD, Libby P, Witztum JL. PMID: 17082490.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    314. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease. Curr Opin Lipidol. 2006 Oct; 17(5):502-9. Fraley AE, Tsimikas S. PMID: 16960498.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    315. Oxidative biomarkers in the diagnosis and prognosis of cardiovascular disease. Am J Cardiol. 2006 Dec 04; 98(11A):9P-17P. Tsimikas S. PMID: 17126679.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    316. Measures of oxidative stress. Clin Lab Med. 2006 Sep; 26(3):571-90, v-vi. Tsimikas S. PMID: 16938585.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    317. Noninvasive imaging of atherosclerotic lesions in apolipoprotein E-deficient and low-density-lipoprotein receptor-deficient mice with annexin A5. J Nucl Med. 2006 Sep; 47(9):1497-505. Isobe S, Tsimikas S, Zhou J, Fujimoto S, Sarai M, Branks MJ, Fujimoto A, Hofstra L, Reutelingsperger CP, Murohara T, Virmani R, Kolodgie FD, Narula N, Petrov A, Narula J. PMID: 16954559.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    318. Statin-associated pleiotropy: possible beneficial effects beyond cholesterol reduction. Pharmacotherapy. 2006 Jul; 26(7 Pt 2):85S-97S; discussion 98S-101S; quiz 106S-108S. Ito MK, Talbert RL, Tsimikas S. PMID: 16803418.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    319. Successful utilization of a novel aspiration thrombectomy catheter (Pronto) for the treatment of patients with stent thrombosis. Catheter Cardiovasc Interv. 2006 Jun; 67(6):894-9. Siddiqui DS, Choi CJ, Tsimikas S, Mahmud E. PMID: 16649245.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    320. Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study. J Am Coll Cardiol. 2006 Jun 20; 47(12):2436-43. Mayr M, Kiechl S, Tsimikas S, Miller E, Sheldon J, Willeit J, Witztum JL, Xu Q. PMID: 16781371.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    321. Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study. J Am Coll Cardiol. 2006 Jun 06; 47(11):2219-28. Tsimikas S, Kiechl S, Willeit J, Mayr M, Miller ER, Kronenberg F, Xu Q, Bergmark C, Weger S, Oberhollenzer F, Witztum JL. PMID: 16750687.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    322. Imaging vulnerable plaque by ultrasound. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C32-9. DeMaria AN, Narula J, Mahmud E, Tsimikas S. PMID: 16631508.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    323. C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C19-31. Tsimikas S, Willerson JT, Ridker PM. PMID: 16631506.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    324. Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Am Coll Cardiol. 2006 May 02; 47(9):1803-10. Rodenburg J, Vissers MN, Wiegman A, Miller ER, Ridker PM, Witztum JL, Kastelein JJ, Tsimikas S. PMID: 16682304.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    325. Drug-eluting stents and late adverse clinical outcomes lessons learned, lessons awaited. J Am Coll Cardiol. 2006 May 16; 47(10):2112-5. Tsimikas S. PMID: 16697332.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    326. Fibromuscular dysplasia of renal arteries: percutaneous revascularization based on hemodynamic assessment with a pressure measurement guidewire. Catheter Cardiovasc Interv. 2006 Mar; 67(3):434-7. Mahmud E, Brocato M, Palakodeti V, Tsimikas S. PMID: 16475187.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    327. Oxidized low-density lipoprotein biomarkers in atherosclerosis. Curr Atheroscler Rep. 2006 Jan; 8(1):55-61. Tsimikas S. PMID: 16455015.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    328. Highlights of the Year in JACC 2005. J Am Coll Cardiol. 2006 Jan 03; 47(1):184-202. Demaria AN, Ben-Yehuda O, Berman D, Feld GK, Ginsberg J, Greenberg BH, Lew WY, Sahn D, Tsimikas S. PMID: 16386685.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    329. Rapid progression of common femoral artery stenosis leading to development of ischemic foot ulcer following repeated ipsilateral arterial access. Catheter Cardiovasc Interv. 2005 Dec; 66(4):487-90. Guillinta P, Waltman T, Tsimikas S. PMID: 16273576.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    330. Treatment of ischemic stroke complicating cardiac catheterization with systemic thrombolytic therapy. Catheter Cardiovasc Interv. 2005 Nov; 66(3):364-8. Serry R, Tsimikas S, Imbesi SG, Mahmud E. PMID: 16208693.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    331. Relationship of a comprehensive panel of plasma oxidized low-density lipoprotein markers to angiographic restenosis in patients undergoing percutaneous coronary intervention for stable angina. Am Heart J. 2005 Nov; 150(5):1007-14. Segev A, Strauss BH, Witztum JL, Lau HK, Tsimikas S. PMID: 16290986.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    332. Catheter-induced vasospasm of both the right external iliac and right coronary arteries during coronary angiography. Int J Cardiovasc Imaging. 2005 Oct; 21(5):481-5. Shortal BP, Mahmud E, Tsimikas S. PMID: 16175434.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    333. Consequences of cholesteryl ester transfer protein inhibition in patients with familial hypoalphalipoproteinemia. Arterioscler Thromb Vasc Biol. 2005 Sep; 25(9):e133-4. Bisoendial RJ, Hovingh GK, El Harchaoui K, Levels JH, Tsimikas S, Pu K, Zwinderman AE, Kuivenhoven JA, Kastelein JJ, Stroes ES. PMID: 16127020.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    334. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med. 2005 Jul 07; 353(1):46-57. Tsimikas S, Brilakis ES, Miller ER, McConnell JP, Lennon RJ, Kornman KS, Witztum JL, Berger PB. PMID: 16000355.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansCells
    335. Expanded applications of rotational atherectomy in contemporary coronary and peripheral interventional practice. J Invasive Cardiol. 2005 Apr; 17(4):207-10. Mahmud E, Keramati S, Salami A, Palakodeti V, Tsimikas S. PMID: 15831974.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    336. Transcatheter closure of patent foramen ovale for migraine prophylaxis: hope or hype? J Am Coll Cardiol. 2005 Feb 15; 45(4):496-8. Tsimikas S. PMID: 15708693.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    337. High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins. J Lipid Res. 2005 Apr; 46(4):769-78. Schneider M, Witztum JL, Young SG, Ludwig EH, Miller ER, Tsimikas S, Curtiss LK, Marcovina SM, Taylor JM, Lawn RM, Innerarity TL, Pitas RE. PMID: 15654123.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    338. Highlights of the year in JACC 2004. J Am Coll Cardiol. 2005 Jan 04; 45(1):137-53. Demaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Narula J, Sahn D, Tsimikas S. PMID: 15629388.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    339. Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization. Arterioscler Thromb Vasc Biol. 2004 Dec; 24(12):2307-12. Torzewski M, Shaw PX, Han KR, Shortal B, Lackner KJ, Witztum JL, Palinski W, Tsimikas S. PMID: 15528482.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    340. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 2004 Sep 14; 110(11):1406-12. Tsimikas S, Witztum JL, Miller ER, Sasiela WJ, Szarek M, Olsson AG, Schwartz GG, Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators. PMID: 15353498.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCellsCTClinical Trials
    341. Concomitant coronary and multiple arch vessel stenoses in patients treated with external beam radiation: pathophysiological basis and endovascular treatment. Catheter Cardiovasc Interv. 2004 Jul; 62(3):385-90. Cavendish JJ, Berman BJ, Schnyder G, Kerber C, Mahmud E, Turi ZG, Blanchard D, Tsimikas S. PMID: 15224309.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    342. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein. Circulation. 2004 Jun 29; 109(25):3164-70. Tsimikas S, Lau HK, Han KR, Shortal B, Miller ER, Segev A, Curtiss LK, Witztum JL, Strauss BH. PMID: 15184281.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    343. Severe ostial saphenous vein graft disease leading to acute coronary syndromes following proximal aorto-saphenous anastomoses with the symmetry bypass connector device: is it a suture device or a "stent"? J Am Coll Cardiol. 2004 Jan 07; 43(1):133-9. Cavendish JJ, Penny WF, Madani MM, Keramati S, Ben-Yehuda O, Blanchard DG, Mahmud E, Perricone A, Tsimikas S. PMID: 14715195.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    344. Highlights of the year in JACC 2003. J Am Coll Cardiol. 2003 Dec 17; 42(12):2156-66. DeMaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Tsimikas S. PMID: 15560019.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    345. Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). J Biol Chem. 2003 Dec 26; 278(52):52841-7. Edelstein C, Pfaffinger D, Hinman J, Miller E, Lipkind G, Tsimikas S, Bergmark C, Getz GS, Witztum JL, Scanu AM. PMID: 14557258.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    346. Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2003 Mar; 111(6):897-906. Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M, Kodama T, Tsimikas S, Witztum JL, Lu ML, Sakara Y, Chin MT, Libby P, Shi GP. PMID: 12639996; PMCID: PMC153760.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    347. Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J Am Coll Cardiol. 2003 Feb 05; 41(3):360-70. Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E, Juliano J, Witztum JL. PMID: 12575961.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    348. Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century. J Am Coll Cardiol. 2002 Dec 18; 40(12):2122-4. Tsimikas S, Witztum JL. PMID: 12505223.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    349. Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. J Am Soc Nephrol. 2002 Jun; 13(6):1673-81. Palinski W, Tsimikas S. PMID: 12039998.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    350. Non-invasive imaging of vulnerable plaques by molecular targeting of oxidized LDL with tagged oxidation-specific antibodies. J Cell Biochem Suppl. 2002; 39:138-46. Tsimikas S, Shaw PX. PMID: 12552613.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    351. Common femoral artery anatomy is influenced by demographics and comorbidity: implications for cardiac and peripheral invasive studies. Catheter Cardiovasc Interv. 2001 Jul; 53(3):289-95. Schnyder G, Sawhney N, Whisenant B, Tsimikas S, Turi ZG. PMID: 11458402.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    352. Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk. Circulation. 2001 Apr 17; 103(15):1930-2. Tsimikas S, Witztum JL. PMID: 11306518.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    353. Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2001 Jan; 21(1):95-100. Tsimikas S, Palinski W, Witztum JL. PMID: 11145939.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    354. In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression. Arterioscler Thromb Vasc Biol. 2000 Mar; 20(3):689-97. Tsimikas S, Shortal BP, Witztum JL, Palinski W. PMID: 10712392.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    355. Spontaneous coronary artery dissection in patients with renal transplantation. J Invasive Cardiol. 1999 May; 11(5):316-21. Tsimikas S, Giordano FJ, Tarazi RY, Beyer RW. PMID: 10745540.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    356. LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. Arterioscler Thromb Vasc Biol. 1999 Jan; 19(1):122-30. Tsimikas S, Philis-Tsimikas A, Alexopoulos S, Sigari F, Lee C, Reaven PD. PMID: 9888874.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    357. Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo. J Nucl Cardiol. 1999 Jan-Feb; 6(1 Pt 1):41-53. Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. PMID: 10070840.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    358. The role of dietary fatty acids in lipoprotein oxidation and atherosclerosis. Curr Opin Lipidol. 1998 Aug; 9(4):301-7. Tsimikas S, Reaven PD. PMID: 9739484.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    359. Subintimal wire position during angioplasty of a chronic total coronary occlusion: detection and subsequent procedural guidance by intravascular ultrasound. Cathet Cardiovasc Diagn. 1995 Jul; 35(3):262-5. Kimura BJ, Tsimikas S, Bhargava V, DeMaria AN, Penny WF. PMID: 7553837.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    360. Aspergillus brain abscess complicating allergic Aspergillus sinusitis. J Allergy Clin Immunol. 1994 Aug; 94(2 Pt 1):264-7. Tsimikas S, Hollingsworth HM, Nash G. PMID: 8064081.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    361. Influence of beta-adrenergic stimulation and contraction frequency on rat heart interstitial adenosine. Circ Res. 1990 Feb; 66(2):457-68. Fenton RA, Tsimikas S, Dobson JG. PMID: 2153472.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    362. Inhibition of fructose bisphosphatase and stimulation of phosphofructokinase by a stable isosteric phosphonate analog of fructose 2,6-bisphosphate. Arch Biochem Biophys. 1986 Feb 15; 245(1):282-6. McClard RW, Tsimikas S, Schriver KE. PMID: 3004359.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    With one click, see people who:

    Mentor Faculty

    Run Clinical Trials

    See more options in the Advanced Search tab

    Sotirios's Networks
    Concepts (895)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (90)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California