Mary Lewinski

TitleAssistant Adjunct Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0679
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego, San Diego, CAFellowship06/2013Infectious Diseases
    University of California, San Diego, San Diego, CAInternship / Residency06/2010Internal Medicine
    University of California, San Diego, La Jolla, CAM.D.06/2008Medicine
    University of California, San Diego, La Jolla, CAPh.D.09/2005Biomedical Sciences
    University of Southern California, Los Angeles, CAB.A. / B.A.05/2000Philosophy / Political Science

    Collapse Research 
    Collapse Research Activities and Funding
    HIV-1 Modulation of the Ubiquitinome and Its Effects on Cell-to-Cell Transmission
    NIH/NIAID K08AI112394Jan 1, 2015 - Dec 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Beliakova-Bethell N, Hezareh M, Wong JK, Strain MC, Lewinski M, Richman DD, Spina CA. Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART. Virology. 2017 08; 508:127-133. PMID: 28527342.
      View in: PubMed
    2. Lapek JD, Lewinski M, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr. Mol Cell Proteomics. 2017 Aug; 16(8):1447-1461. PMID: 28606917.
      View in: PubMed
    3. Ball KA, Johnson JR, Lewinski M, Guatelli J, Verschueren E, Krogan NJ, Jacobson MP. Non-degradative Ubiquitination of Protein Kinases. PLoS Comput Biol. 2016 06; 12(6):e1004898. PMID: 27253329; PMCID: PMC4890936.
    4. Tokarev A, Stoneham C, Lewinski M, Mukim A, Deshmukh S, Vollbrecht T, Spina CA, Guatelli J. Pharmacologic Inhibition of Nedd8 Activation Enzyme Exposes CD4-Induced Epitopes within Env on Cells Expressing HIV-1. J Virol. 2015 Dec 16; 90(5):2486-502. PMID: 26676780; PMCID: PMC4810708.
    5. Lewinski M, Jafari M, Zhang H, Opella SJ, Guatelli J. Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly. J Biol Chem. 2015 Apr 24; 290(17):10919-33. PMID: 25759385; PMCID: PMC4409254.
    6. Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, Guatelli J, Xiong Y. Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. Elife. 2014 Apr 29; 3:e02362. PMID: 24843023; PMCID: PMC4018625.
    7. Jafari M, Guatelli J, Lewinski M. Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release. J Virol. 2014 May; 88(9):5062-78. PMID: 24574397; PMCID: PMC3993827.
    8. Sherrill-Mix S, Lewinski M, Famiglietti M, Bosque A, Malani N, Ocwieja KE, Berry CC, Looney D, Shan L, Agosto LM, Pace MJ, Siliciano RF, O'Doherty U, Guatelli J, Planelles V, Bushman FD. HIV latency and integration site placement in five cell-based models. Retrovirology. 2013 Aug 16; 10:90. PMID: 23953889; PMCID: PMC3765678.
    9. Lewinski M, Yamashita M, Emerman M, Ciuffi A, Marshall H, Crawford G, Collins F, Shinn P, Leipzig J, Hannenhalli S, Berry CC, Ecker JR, Bushman FD. Retroviral DNA integration: viral and cellular determinants of target-site selection. PLoS Pathog. 2006 Jun; 2(6):e60. PMID: 16789841; PMCID: PMC1480600.
    10. Bushman F, Lewinski M, Ciuffi A, Barr S, Leipzig J, Hannenhalli S, Hoffmann C. Genome-wide analysis of retroviral DNA integration. Nat Rev Microbiol. 2005 Nov; 3(11):848-58. PMID: 16175173.
      View in: PubMed
    11. Bisgrove D, Lewinski M, Bushman F, Verdin E. Molecular mechanisms of HIV-1 proviral latency. Expert Rev Anti Infect Ther. 2005 Oct; 3(5):805-14. PMID: 16207172.
      View in: PubMed
    12. Lewinski M, Bisgrove D, Shinn P, Chen H, Hoffmann C, Hannenhalli S, Verdin E, Berry CC, Ecker JR, Bushman FD. Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription. J Virol. 2005 Jun; 79(11):6610-9. PMID: 15890899; PMCID: PMC1112149.
    13. Lewinski M, Bushman FD. Retroviral DNA integration--mechanism and consequences. Adv Genet. 2005; 55:147-81. PMID: 16291214.
      View in: PubMed