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Kevin Corbett

Title(s)Associate Professor, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
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    Harvard Medical SchoolPostdoctoral2011Biological Chemistry & Molecular Pharmacology
    University of California, BerkeleyPh.D.2005Molecular Cell Biology
    University of VirginiaB.S.2000Chemistry

    Collapse Overview 
    Collapse Overview
    Our lab is focused on the molecular mechanisms of chromosome segregation in meiosis. We use biochemistry, X-ray crystallography, and genetics in S. cerevisiae to probe the structure, function, and interactions between proteins involved in meiotic chromosome pairing, crossover initiation and maturation, and chromosome segregation. A new focus involves the structure and function of the first identified bacterial HORMA domain proteins, a family of signaling proteins previously thought to exist only in eukaryotes.

    Collapse Research 
    Collapse Research Activities and Funding
    Molecular mechanisms of the first-identified bacterial HORMA and Pch2-like proteins in a novel second-messenger signaling pathway
    NIH/NIAID R21AI148814Jan 17, 2020 - Dec 31, 2021
    Role: Principal Investigator
    Expanding the CRISPR/Cas toolbox for RNA modulation
    NIH/NIGMS R01GM128464May 21, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Molecular mechanisms of chromosome organization and recombination control by the meiotic chromosome axis
    NIH/NIGMS R01GM104141Dec 10, 2012 - Nov 30, 2017
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020 Sep 14. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32970989.
      View in: PubMed   Mentions: 4     Fields:    
    2. The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. bioRxiv. 2020 Jul 31. Lu S, Ye Q, Singh D, Villa E, Cleveland DW, Corbett KD. PMID: 32766587.
      View in: PubMed   Mentions:
    3. SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. bioRxiv. 2020 Jul 14. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Painter CD, Thacker BE, Glass CA, Narayanan A, Majowicz SA, Zhang Y, Torres JL, Golden GJ, Porell R, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser B, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Leibel SL, Chanda SK, Schmidt AG, Godula K, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32699853.
      View in: PubMed   Mentions:
    4. Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. Protein Sci. 2020 Jul 12. Ye Q, West AMV, Silletti S, Corbett KD. PMID: 32654247.
      View in: PubMed   Mentions: 4     Fields:    
    5. The odds and implications of coinheritance of hemophilia A and B. Res Pract Thromb Haemost. 2020 Jul; 4(5):931-935. Karch C, Masser-Frye D, Limjoco J, Ryan SE, Fletcher SN, Corbett KD, Johnsen JM, Thornburg CD. PMID: 32685904.
      View in: PubMed   Mentions:
    6. Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. bioRxiv. 2020 May 17. Ye Q, West AMV, Silletti S, Corbett KD. PMID: 32511359.
      View in: PubMed   Mentions:
    7. Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein. J Biol Chem. 2020 Feb 28; 295(9):2804-2821. Sandoval DR, Gomez Toledo A, Painter CD, Tota EM, Sheikh MO, West AMV, Frank MM, Wells L, Xu D, Bicknell R, Corbett KD, Esko JD. PMID: 31964714.
      View in: PubMed   Mentions:    Fields:    
    8. Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Mol Cell. 2020 02 20; 77(4):723-733.e6. Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. PMID: 31932164.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    9. HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol Cell. 2020 02 20; 77(4):709-722.e7. Ye Q, Lau RK, Mathews IT, Birkholz EA, Watrous JD, Azimi CS, Pogliano J, Jain M, Corbett KD. PMID: 31932165.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    10. Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18423-18428. Xu H, Tong Z, Ye Q, Sun T, Hong Z, Zhang L, Bortnick A, Cho S, Beuzer P, Axelrod J, Hu Q, Wang M, Evans SM, Murre C, Lu LF, Sun S, Corbett KD, Cang H. PMID: 31444302.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    11. The molecular basis of monopolin recruitment to the kinetochore. Chromosoma. 2019 09; 128(3):331-354. Plowman R, Singh N, Tromer EC, Payan A, Duro E, Spanos C, Rappsilber J, Snel B, Kops GJPL, Corbett KD, Marston AL. PMID: 31037469.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic crossover formation through structure-specific DNA binding. Nucleic Acids Res. 2019 03 18; 47(5):2365-2376. Arora K, Corbett KD. PMID: 30566683.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase. Nat Struct Mol Biol. 2019 03; 26(3):164-174. Patel L, Kang R, Rosenberg SC, Qiu Y, Raviram R, Chee S, Hu R, Ren B, Cole F, Corbett KD. PMID: 30778236.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    14. A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. Elife. 2019 01 18; 8. West AM, Rosenberg SC, Ur SN, Lehmer MK, Ye Q, Hagemann G, Caballero I, Usón I, MacQueen AJ, Herzog F, Corbett KD. PMID: 30657449.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    15. The budding-yeast RWD protein Csm1 scaffolds diverse protein complexes through a conserved structural mechanism. Protein Sci. 2018 12; 27(12):2094-2100. Singh N, Corbett KD. PMID: 30252178.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC. Nat Commun. 2018 10 19; 9(1):4354. Kim DH, Han JS, Ly P, Ye Q, McMahon MA, Myung K, Corbett KD, Cleveland DW. PMID: 30341343.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    17. Author Correction: Blocking Zika virus vertical transmission. Sci Rep. 2018 Jun 05; 8(1):8794. Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29867187.
      View in: PubMed   Mentions: 1     Fields:    
    18. Blocking Zika virus vertical transmission. Sci Rep. 2018 01 19; 8(1):1218. Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29352135.
      View in: PubMed   Mentions: 9     Fields:    
    19. Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2. Nucleic Acids Res. 2018 01 09; 46(1):279-292. West AMV, Komives EA, Corbett KD. PMID: 29186573.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    20. Identification of H3K4me1-associated proteins at mammalian enhancers. Nat Genet. 2018 01; 50(1):73-82. Local A, Huang H, Albuquerque CP, Singh N, Lee AY, Wang W, Wang C, Hsia JE, Shiau AK, Ge K, Corbett KD, Wang D, Zhou H, Ren B. PMID: 29255264.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    21. Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9. Cell. 2017 Aug 24; 170(5):899-912.e10. Batra R, Nelles DA, Pirie E, Blue SM, Marina RJ, Wang H, Chaim IA, Thomas JD, Zhang N, Nguyen V, Aigner S, Markmiller S, Xia G, Corbett KD, Swanson MS, Yeo GW. PMID: 28803727.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    22. The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. EMBO J. 2017 08 15; 36(16):2419-2434. Ye Q, Kim DH, Dereli I, Rosenberg SC, Hagemann G, Herzog F, Tóth A, Cleveland DW, Corbett KD. PMID: 28659378.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    23. Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Dev Cell. 2017 05 22; 41(4):424-437.e4. Cheerambathur DK, Prevo B, Hattersley N, Lewellyn L, Corbett KD, Oegema K, Desai A. PMID: 28535376.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    24. Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity. Genes Dev. 2017 04 15; 31(8):802-815. Liang J, Singh N, Carlson CR, Albuquerque CP, Corbett KD, Zhou H. PMID: 28487408.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    25. Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing. Prog Mol Subcell Biol. 2017; 56:429-455. Corbett KD. PMID: 28840248.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    26. Molecular Architecture of the Yeast Monopolin Complex. Cell Rep. 2016 10 11; 17(3):929. Corbett KD, Harrison SC. PMID: 27732865.
      View in: PubMed   Mentions:    Fields:    
    27. Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator. EMBO J. 2016 10 04; 35(19):2139-2151. Ye Q, Ur SN, Su TY, Corbett KD. PMID: 27491543.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    28. Data publication with the structural biology data grid supports live analysis. Nat Commun. 2016 Mar 07; 7:10882. Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. PMID: 26947396.
      View in: PubMed   Mentions: 42     Fields:    
    29. A Chemical and Enzymatic Approach to Study Site-Specific Sumoylation. PLoS One. 2015; 10(12):e0143810. Albuquerque CP, Yeung E, Ma S, Fu T, Corbett KD, Zhou H. PMID: 26633173.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    30. The multifaceted roles of the HORMA domain in cellular signaling. J Cell Biol. 2015 Nov 23; 211(4):745-55. Rosenberg SC, Corbett KD. PMID: 26598612.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    31. Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble aß-tubulin pool for microtubule dynamics. Elife. 2015 Jul 24; 4. Nithianantham S, Le S, Seto E, Jia W, Leary J, Corbett KD, Moore JK, Al-Bassam J. PMID: 26208336.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    32. TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. Elife. 2015 Apr 28; 4. Ye Q, Rosenberg SC, Moeller A, Speir JA, Su TY, Corbett KD. PMID: 25918846.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    33. The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins. Dev Cell. 2014 Nov 24; 31(4):487-502. Kim Y, Rosenberg SC, Kugel CL, Kostow N, Rog O, Davydov V, Su TY, Dernburg AF, Corbett KD. PMID: 25446517.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    34. Sister kinetochores are mechanically fused during meiosis I in yeast. Science. 2014 Oct 10; 346(6206):248-51. Sarangapani KK, Duro E, Deng Y, Alves Fde L, Ye Q, Opoku KN, Ceto S, Rappsilber J, Corbett KD, Biggins S, Marston AL, Asbury CL. PMID: 25213378.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    35. A new piece in the kinetochore jigsaw puzzle. J Cell Biol. 2014 Aug 18; 206(4):457-9. Corbett KD, Desai A. PMID: 25135931.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    36. Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits. Mol Biol Cell. 2013 Sep; 24(17):2727-38. Bhandari D, Zhang J, Menon S, Lord C, Chen S, Helm JR, Thorsen K, Corbett KD, Hay JC, Ferro-Novick S. PMID: 23864707.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    37. Stable RAGE-heparan sulfate complexes are essential for signal transduction. ACS Chem Biol. 2013 Jul 19; 8(7):1611-20. Xu D, Young JH, Krahn JM, Song D, Corbett KD, Chazin WJ, Pedersen LC, Esko JD. PMID: 23679870.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    38. a-Tubulin acetylation from the inside out. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19515-6. Al-Bassam J, Corbett KD. PMID: 23150594.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    39. Molecular architecture of the yeast monopolin complex. Cell Rep. 2012 Jun 28; 1(6):583-9. Corbett KD, Harrison SC. PMID: 22813733.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    40. Structure, assembly and reading of centromeric chromatin. Curr Opin Genet Dev. 2012 Apr; 22(2):139-47. Maddox PS, Corbett KD, Desai A. PMID: 22178421.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    41. Molecular structures and interactions in the yeast kinetochore. Cold Spring Harb Symp Quant Biol. 2010; 75:395-401. Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC. PMID: 21467141.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    42. Structure of the ATP-binding domain of Plasmodium falciparum Hsp90. Proteins. 2010 Oct; 78(13):2738-44. Corbett KD, Berger JM. PMID: 20635416.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    43. The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell. 2010 Aug 20; 142(4):556-67. Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC. PMID: 20723757.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    44. Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nat Struct Mol Biol. 2010 Apr; 17(4):438-44. Abraham J, Corbett KD, Farzan M, Choe H, Harrison SC. PMID: 20208545.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    45. How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II topoisomerases. J Mol Biol. 2009 Feb 06; 385(5):1397-408. Stuchinskaya T, Mitchenall LA, Schoeffler AJ, Corbett KD, Berger JM, Bates AD, Maxwell A. PMID: 19094994.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    46. Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI. Nat Struct Mol Biol. 2007 Jul; 14(7):611-9. Corbett KD, Benedetti P, Berger JM. PMID: 17603498.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    47. Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2. Protein Sci. 2007 Apr; 16(4):695-703. Douglas AE, Corbett KD, Berger JM, McFadden G, Handel TM. PMID: 17384234.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    48. Structural basis for topoisomerase VI inhibition by the anti-Hsp90 drug radicicol. Nucleic Acids Res. 2006; 34(15):4269-77. Corbett KD, Berger JM. PMID: 16920739.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    49. Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface. J Biol Chem. 2006 Sep 08; 281(36):26745-53. Reynolds KA, Thomson JM, Corbett KD, Bethel CR, Berger JM, Kirsch JF, Bonomo RA, Handel TM. PMID: 16809340.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    50. The structural basis for substrate specificity in DNA topoisomerase IV. J Mol Biol. 2005 Aug 19; 351(3):545-61. Corbett KD, Schoeffler AJ, Thomsen ND, Berger JM. PMID: 16023670.
      View in: PubMed   Mentions: 75     Fields:    Translation:Cells
    51. Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI. Structure. 2005 Jun; 13(6):873-82. Corbett KD, Berger JM. PMID: 15939019.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    52. Developing promiscuous glycosidases for glycoside synthesis: residues W433 and E432 in Sulfolobus solfataricus beta-glycosidase are important glucoside- and galactoside-specificity determinants. Chembiochem. 2005 May; 6(5):866-75. Hancock SM, Corbett K, Fordham-Skelton AP, Gatehouse JA, Davis BG. PMID: 15846595.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    53. Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase. Biochemistry. 2004 Oct 12; 43(40):12780-7. Chow MA, McElroy KE, Corbett KD, Berger JM, Kirsch JF. PMID: 15461450.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    54. The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7293-8. Corbett KD, Shultzaberger RK, Berger JM. PMID: 15123801.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    55. Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases. Annu Rev Biophys Biomol Struct. 2004; 33:95-118. Corbett KD, Berger JM. PMID: 15139806.
      View in: PubMed   Mentions: 149     Fields:    Translation:Cells
    56. Emerging roles for plant topoisomerase VI. Chem Biol. 2003 Feb; 10(2):107-11. Corbett KD, Berger JM. PMID: 12618182.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    57. Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution. EMBO J. 2003 Jan 02; 22(1):151-63. Corbett KD, Berger JM. PMID: 12505993.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    58. A Rho-like small GTPase of Entamoeba histolytica contains an unusual amino acid residue in a conserved GDP-stabilization region and is not a substrate for C3 exoenzyme. Exp Parasitol. 2002 Jun-Jul; 101(2-3):107-10. Godbold GD, Corbett KD, Mann BJ. PMID: 12427464.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    59. Tailoring the substrate specificity of the beta-glycosidase from the thermophilic archaeon Sulfolobus solfataricus. FEBS Lett. 2001 Dec 14; 509(3):355-60. Corbett K, Fordham-Skelton AP, Gatehouse JA, Davis BG. PMID: 11749955.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    60. The many faces of Ras: recognition of small GTP-binding proteins. Trends Biochem Sci. 2001 Dec; 26(12):710-6. Corbett KD, Alber T. PMID: 11738594.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    61. Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences. Clin Pharmacol Ther. 1998 Sep; 64(3):237-47. Greenblatt DJ, Wright CE, von Moltke LL, Harmatz JS, Ehrenberg BL, Harrel LM, Corbett K, Counihan M, Tobias S, Shader RI. PMID: 9757147.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
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