Kamil Godula

Title(s)	Professor, Chemistry and Biochemistry
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
vCard	Download vCard

Research

research activities and funding

Glycan engineering via exoplasmic Golgi shuttle of glycosylation building blocks and modulators
NIH R21GM134315Jul 1, 2019 - Jun 30, 2021
Role: Principal Investigator

UCSD Biomedical Scientist Career Development Program in Glycoscience
NIH K12HL141956Jul 1, 2018 - Jun 30, 2023
Role: Co-Principal Investigator

Glycan array for phenotype-driven capture and genotyping of viruses in primary isolates
NIH R21AI129894Sep 1, 2016 - Aug 31, 2019
Role: Principal Investigator

In vivo glycan engineering at the cell-matrix interface to control stem cell fate
NIH DP2HD087954Sep 30, 2015 - Jun 30, 2020
Role: Principal Investigator

NeoProteoglycans as synthetic materials for regenerative medicine and bioimaging
NIH R00EB013446Sep 1, 2013 - Aug 31, 2016
Role: Principal Investigator

NeoProteoglycans as synthetic materials for regenerative medicine and bioimaging
NIH K99EB013446Jul 1, 2011 - Aug 31, 2013
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth. ACS Chem Biol. 2024 08 16; 19(8):1820-1835. Painter CD, Sankaranarayanan NV, Nagarajan B, Mandel Clausen T, West AMV, Setiawan NJ, Park J, Porell RN, Bartels PL, Sandoval DR, Vasquez GJ, Chute JP, Godula K, Vander Kooi CW, Gordts PLSM, Corbett KD, Termini CM, Desai UR, Esko JD. PMID: 39099090; PMCID: PMC11334110.

View in: PubMed Mentions: Fields:
Bio Biochemistry Bio Biology
Translation:Animals Cells
Human extracellular sulfatases use a dual mechanism for regulation of growth factor interactions with heparan sulfate proteoglycans. bioRxiv. 2023 Nov 22. Timm BM, Follmar JL, Porell RN, Glass K, Thacker BE, Glass CA, Godula K. PMID: 38045270; PMCID: PMC10690288.

View in: PubMed Mentions:
Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism. J Biol Chem. 2023 05; 299(5):104611. Trieger GW, Pessentheiner AR, Purcell SC, Green CR, DeForest N, Willert K, Majithia AR, Metallo CM, Godula K, Gordts PLSM. PMID: 36931394; PMCID: PMC10164900.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry
Biologically Derived Neoproteoglycans for Profiling Protein-Glycosaminoglycan Interactions. ACS Chem Biol. 2022 06 17; 17(6):1534-1542. Porell RN, Follmar JL, Purcell SC, Timm B, Laubach LK, Kozirovskiy D, Thacker BE, Glass CA, Gordts PLSM, Godula K. PMID: 35574759.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry Bio Biology
Translation:Humans Cells
Cell surface photoengineering enables modeling of glycocalyx shedding dynamics. Chem Sci. 2022 Jun 07; 13(22):6626-6635. Purcell SC, Zhang MH, Honigfort DJ, Ng HJC, Michalak AL, Godula K. PMID: 35756522; PMCID: PMC9172368.

View in: PubMed Mentions: 1
Author Correction: Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2022 May; 18(5):575. Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 35354934.

View in: PubMed Mentions: Fields:
Bio Biology Che Chemistry
PABP1 Drives the Selective Translation of Influenza A Virus mRNA. J Mol Biol. 2022 03 15; 434(5):167460. de Rozières CM, Pequeno A, Shahabi S, Lucas TM, Godula K, Ghosh G, Joseph S. PMID: 35074482; PMCID: PMC8897273.

View in: PubMed Mentions: 5 Fields:
Mol Molecular Biology
Translation:Humans Cells
Mucin-mimetic glycan arrays integrating machine learning for analyzing receptor pattern recognition by influenza A viruses. Chem. 2021 Dec 09; 7(12):3393-3411. Lucas TM, Gupta C, Altman MO, Sanchez E, Naticchia MR, Gagneux P, Singharoy A, Godula K. PMID: 34993358; PMCID: PMC8726012.

View in: PubMed Mentions: 9
Glycocalyx crowding with mucin mimetics strengthens binding of soluble and virus-associated lectins to host cell glycan receptors. Proc Natl Acad Sci U S A. 2021 10 05; 118(40). Honigfort DJ, Altman MO, Gagneux P, Godula K. PMID: 34583992; PMCID: PMC8501829.

View in: PubMed Mentions: 12 Fields:
Sci Science
Translation:Humans Cells
Stem Cell Microarrays for Assessing Growth Factor Signaling in Engineered Glycan Microenvironments. Adv Healthc Mater. 2022 02; 11(4):e2101232. Michalak AL, Trieger GW, Trieger KA, Godula K. PMID: 34541824; PMCID: PMC8854331.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Tec Technology
Translation:Animals Cells
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2021 06; 17(6):684-692. Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 33846619; PMCID: PMC8159865.

View in: PubMed Mentions: 10 Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
Spatially controlled glycocalyx engineering for growth factor patterning in embryoid bodies. Biomater Sci. 2021 Mar 10; 9(5):1652-1659. Naticchia MR, Laubach LK, Honigfort DJ, Purcell SC, Godula K. PMID: 33409513; PMCID: PMC7970653.

View in: PubMed Mentions: 4 Fields:
Bio Biomedical Engineering The Therapeutics
Translation:Cells
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020 11 12; 183(4):1043-1057.e15. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32970989; PMCID: PMC7489987.

View in: PubMed Mentions: 655 Fields:
Cel Cell Biology
Translation:Humans Cells PHPublic Health
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. bioRxiv. 2020 Jul 14. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Painter CD, Thacker BE, Glass CA, Narayanan A, Majowicz SA, Zhang Y, Torres JL, Golden GJ, Porell R, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser B, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Leibel SL, Chanda SK, Schmidt AG, Godula K, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32699853; PMCID: PMC7373134.

View in: PubMed Mentions:
Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries. Faraday Discuss. 2019 10 30; 219(0):138-153. Honigfort DJ, Zhang MH, Verespy S, Godula K. PMID: 31313786; PMCID: PMC6824934.

View in: PubMed Mentions: 6 Fields:
Che Chemistry
Translation:Humans Animals Cells
Preparation of multivalent glycan micro- and nano-arrays: general discussion. Faraday Discuss. 2019 10 30; 219(0):128-137. Braunschweig A, Byrne JP, Chiechi R, Diaz Fernandez Y, Gildersleeve J, Godula K, Hartmann L, Mahon C, Miura Y, Nelson A, Schmidt S, Turnbull WB, Valles D, Yu J, Zhou D. PMID: 31560357.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Humans Animals Cells
Glycan interactions on glycocalyx mimetic surfaces: general discussion. Faraday Discuss. 2019 10 30; 219(0):183-188. Azevedo HS, Braunschweig AB, Chiechi RC, Diaz Fernandez Y, Gildersleeve JC, Godula K, Hartmann L, Miura Y, Schmidt S, Turnbull WB, Zhou D. PMID: 31591625.

View in: PubMed Mentions: Fields:
Che Chemistry
Translation:Humans Animals Cells
Silencing glycosaminoglycan functions in mouse embryonic stem cells with small molecule antagonists. Methods Enzymol. 2019; 626:249-270. Chatterjee S, Stephenson TN, Michalak AL, Godula K, Huang ML. PMID: 31606078; PMCID: PMC7265920.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry
Translation:Animals Cells
Surface Sugars Get Cells in Shape. Cell. 2019 06 13; 177(7):1672-1674. Godula K. PMID: 31199912.

View in: PubMed Mentions: 3 Fields:
Cel Cell Biology
Translation:Cells
Synthetic glycoscapes: addressing the structural and functional complexity of the glycocalyx. Interface Focus. 2019 Apr 06; 9(2):20180080. Purcell SC, Godula K. PMID: 30842878; PMCID: PMC6388016.

View in: PubMed Mentions: 22
Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface. Bioconjug Chem. 2019 03 20; 30(3):833-840. Trieger GW, Verespy S, Gordts PLSM, Godula K. PMID: 30668905; PMCID: PMC6860979.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry
Translation:Animals Cells
Embryonic Stem Cell Engineering with a Glycomimetic FGF2/BMP4 Co-Receptor Drives Mesodermal Differentiation in a Three-Dimensional Culture. ACS Chem Biol. 2018 10 19; 13(10):2880-2887. Naticchia MR, Laubach LK, Tota EM, Lucas TM, Huang ML, Godula K. PMID: 30157624; PMCID: PMC6252183.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry Bio Biology
Translation:Humans Cells
Influencing Early Stages of Neuromuscular Junction Formation through Glycocalyx Engineering. ACS Chem Neurosci. 2018 12 19; 9(12):3086-3093. Huang ML, Tota EM, Lucas TM, Godula K. PMID: 30095249; PMCID: PMC6395550.

View in: PubMed Mentions: 9 Fields:
Neu Neurology
Translation:Animals Cells
Glycocalyx Scaffolding to Control Cell Surface Glycan Displays. Curr Protoc Chem Biol. 2018 06; 10(2):e40. Huang ML, Tota EM, Verespy S, Godula K. PMID: 29927116; PMCID: PMC6020046.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Che Chemistry Techniques
Translation:Animals Cells
Following sugar patterns in search of galectin function. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):2548-2550. Godula K. PMID: 29496962; PMCID: PMC5856567.

View in: PubMed Mentions: 4 Fields:
Sci Science
Translation:Cells
Heparin-fibronectin interactions in the development of extracellular matrix insolubility. Matrix Biol. 2018 04; 67:107-122. Raitman I, Huang ML, Williams SA, Friedman B, Godula K, Schwarzbauer JE. PMID: 29223498; PMCID: PMC5910196.

View in: PubMed Mentions: 16 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Animals Cells
Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State. Stem Cells. 2018 01; 36(1):45-54. Huang ML, Michalak AL, Fisher CJ, Christy M, Smith RAA, Godula K. PMID: 28984039; PMCID: PMC6237099.

View in: PubMed Mentions: 9 Fields:
Cel Cell Biology Emb Embryology
Translation:Animals Cells
Glycocalyx scaffolding with synthetic nanoscale glycomaterials. Biomater Sci. 2017 07 25; 5(8):1537-1540. Huang ML, Purcell SC, Verespy S, Wang Y, Godula K. PMID: 28616946; PMCID: PMC5560263.

View in: PubMed Mentions: 9 Fields:
Bio Biomedical Engineering The Therapeutics
Translation:Animals Cells
Human milk oligosaccharides inhibit growth of group B Streptococcus. J Biol Chem. 2017 07 07; 292(27):11243-11249. Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. PMID: 28416607; PMCID: PMC5500792.

View in: PubMed Mentions: 78 Fields:
Bio Biochemistry
Translation:Humans Cells
Synthetic Mucus Nanobarriers for Identification of Glycan-Dependent Primary Influenza A Infection Inhibitors. ACS Cent Sci. 2016 Oct 26; 2(10):710-714. Cohen M, Senaati HP, Fisher CJ, Huang ML, Gagneux P, Godula K. PMID: 27800553; PMCID: PMC5084083.

View in: PubMed Mentions: 5
Glycomaterials for probing host-pathogen interactions and the immune response. Exp Biol Med (Maywood). 2016 05; 241(10):1042-53. Huang ML, Fisher CJ, Godula K. PMID: 27190259; PMCID: PMC4950362.

View in: PubMed Mentions: 4 Fields:
Bio Biology Med Medicine (General)Phy Physiology
Translation:Humans Animals
Capture and characterization of influenza A virus from primary samples using glycan bead arrays. Virology. 2016 06; 493:128-35. Cohen M, Fisher CJ, Huang ML, Lindsay LL, Plancarte M, Boyce WM, Godula K, Gagneux P. PMID: 27031581; PMCID: PMC4860064.

View in: PubMed Mentions: 7 Fields:
Vir Virology
Translation:Animals Cells
Nanoscale materials for probing the biological functions of the glycocalyx. Glycobiology. 2016 08; 26(8):797-803. Huang ML, Godula K. PMID: 26916883; PMCID: PMC5018045.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Humans Cells
Glycocalyx Remodeling with Glycopolymer-Based Proteoglycan Mimetics. Methods Mol Biol. 2016; 1367:207-24. Huang ML, Smith RA, Trieger GW, Godula K. PMID: 26537476; PMCID: PMC6576258.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology
Translation:Animals Cells
Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays. Chem Commun (Camb). 2015 Mar 28; 51(25):5326-9. Huang ML, Cohen M, Fisher CJ, Schooley RT, Gagneux P, Godula K. PMID: 25574528; PMCID: PMC4359031.

View in: PubMed Mentions: 22 Fields:
Che Chemistry
Translation:Cells
Priming the cellular glycocalyx for neural development. ACS Chem Neurosci. 2014 Oct 15; 5(10):873-5. Huang ML, Godula K. PMID: 25210831; PMCID: PMC4198060.

View in: PubMed Mentions: 5 Fields:
Neu Neurology
Translation:Humans Animals Cells
Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells. J Am Chem Soc. 2014 Jul 30; 136(30):10565-8. Huang ML, Smith RA, Trieger GW, Godula K. PMID: 25019314; PMCID: PMC4121001.

View in: PubMed Mentions: 56 Fields:
Che Chemistry
Translation:Animals Cells
The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 2014 Jul 17; 511(7509):319-25. Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM. PMID: 25030168; PMCID: PMC4487551.

View in: PubMed Mentions: 288 Fields:
Sci Science
Chemoenzymatic Fc glycosylation via engineered aldehyde tags. Bioconjug Chem. 2014 Apr 16; 25(4):788-95. Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR. PMID: 24702330; PMCID: PMC4004622.

View in: PubMed Mentions: 19 Fields:
Bio Biochemistry
Translation:Animals Cells
Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers. PLoS One. 2013; 8(8):e72304. Mauris J, Mantelli F, Woodward AM, Cao Z, Bertozzi CR, Panjwani N, Godula K, Argüeso P. PMID: 23977277; PMCID: PMC3747151.

View in: PubMed Mentions: 27 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals Cells
Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins. J Am Chem Soc. 2012 Sep 26; 134(38):15732-42. Godula K, Bertozzi CR. PMID: 22967056; PMCID: PMC3458438.

View in: PubMed Mentions: 43 Fields:
Che Chemistry
Translation:Cells
Synthesis of glycopolymers for microarray applications via ligation of reducing sugars to a poly(acryloyl hydrazide) scaffold. J Am Chem Soc. 2010 Jul 28; 132(29):9963-5. Godula K, Bertozzi CR. PMID: 20608651; PMCID: PMC2907714.

View in: PubMed Mentions: 30 Fields:
Che Chemistry
Translation:Humans Cells
Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. J Am Chem Soc. 2009 Jul 29; 131(29):10263-8. Godula K, Umbel ML, Rabuka D, Botyanszki Z, Bertozzi CR, Parthasarathy R. PMID: 19580278; PMCID: PMC2716393.

View in: PubMed Mentions: 16 Fields:
Che Chemistry
Translation:Cells
Expeditious synthesis of contorted hexabenzocoronenes. Org Lett. 2009 Jun 04; 11(11):2225-8. Plunkett KN, Godula K, Nuckolls C, Tremblay N, Whalley AC, Xiao S. PMID: 19391615.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry
Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications. Angew Chem Int Ed Engl. 2009; 48(27):4973-6. Godula K, Rabuka D, Nam KT, Bertozzi CR. PMID: 19479916; PMCID: PMC2735190.

View in: PubMed Mentions: 32 Fields:
Che Chemistry
C-H bond functionalization in complex organic synthesis. Science. 2006 Apr 07; 312(5770):67-72. Godula K, Sames D. PMID: 16601184.

View in: PubMed Mentions: 163 Fields:
Sci Science
Site-specific phenylation of pyridine catalyzed by phosphido-bridged ruthenium dimer complexes: a prototype for C-H arylation of electron-deficient heteroarenes. J Am Chem Soc. 2005 Mar 23; 127(11):3648-9. Godula K, Sezen B, Sames D. PMID: 15771470.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Cells
Iron-mediated preparation of vinylcyclopropanecarboxylates: scope, mechanism, and applications. J Org Chem. 2003 Feb 07; 68(3):901-10. Yun YK, Godula K, Cao Y, Donaldson WA. PMID: 12558414.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Translation:Cells
C-C bond formation via C-H bond activation: synthesis of the core of teleocidin B4. J Am Chem Soc. 2002 Oct 09; 124(40):11856-7. Dangel BD, Godula K, Youn SW, Sezen B, Sames D. PMID: 12358522.

View in: PubMed Mentions: 14 Fields:
Che Chemistry
A simple and efficient synthesis of optically pure tricarbonyl(methyl 6-oxo-2,4-hexadienoate)iron. J Org Chem. 2001 May 18; 66(10):3590-2. Godula K, Bärmann H, Donaldson WA. PMID: 11348149.

View in: PubMed Mentions: 1 Fields:
Che Chemistry