Sara Brin Rosenthal

Title(s)Senior Bioinformatics Scientist, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0681
La Jolla CA 92093
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    Princeton University, Princeton, NJPh.D.Biophysics
    Cornell University, Ithaca, NYB.A.Physics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Proc Natl Acad Sci U S A. 2021 Jul 20; 118(29). Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, Brenner DA, Kisseleva T. PMID: 34253615.
      View in: PubMed   Mentions: 1     Fields:    
    2. Nondegradable Collagen Increases Liver Fibrosis but Not Hepatocellular Carcinoma in Mice. Am J Pathol. 2021 Jun 11. Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal SB, Dhar D, Su H, Cong M, Jia J, Hosseini M, Karin M, Kisseleva T, Brenner DA. PMID: 34119473.
      View in: PubMed   Mentions:    Fields:    
    3. Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet. Cell Mol Gastroenterol Hepatol. 2021 May 29. Ganguly S, Muench GA, Shang L, Rosenthal SB, Rahman G, Wang R, Wang Y, Kwon HC, Diomino AM, Kisseleva T, Soorosh P, Hosseini M, Knight R, Schnabl B, Brenner DA, Dhar D. PMID: 34062281.
      View in: PubMed   Mentions:    Fields:    
    4. Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes. Front Aging Neurosci. 2021; 13:674318. Wang H, Lo MT, Rosenthal SB, Makowski C, Andreassen OA, Salem RM, McEvoy LK, Fiecas M, Chen CH. PMID: 34122051.
      View in: PubMed   Mentions:
    5. Functional landscape of SARS-CoV-2 cellular restriction. Mol Cell. 2021 06 17; 81(12):2656-2668.e8. Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Curry HM, Oom AL, Miorin L, Rodriguez-Frandsen A, Zheng F, Wu C, Xiong Y, Urbanowski M, Shaw ML, Chang MW, Benner C, Hope TJ, Frieman MB, García-Sastre A, Ideker T, Hultquist JF, Guatelli J, Chanda SK. PMID: 33930332.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data. iScience. 2021 Apr 23; 24(4):102361. Overbey EG, Saravia-Butler AM, Zhang Z, Rathi KS, Fogle H, da Silveira WA, Barker RJ, Bass JJ, Beheshti A, Berrios DC, Blaber EA, Cekanaviciute E, Costa HA, Davin LB, Fisch KM, Gebre SG, Geniza M, Gilbert R, Gilroy S, Hardiman G, Herranz R, Kidane YH, Kruse CPS, Lee MD, Liefeld T, Lewis NG, McDonald JT, Meller R, Mishra T, Perera IY, Ray S, Reinsch SS, Rosenthal SB, Strong M, Szewczyk NJ, Tahimic CGT, Taylor DM, Vandenbrink JP, Villacampa A, Weging S, Wolverton C, Wyatt SE, Zea L, Costes SV, Galazka JM. PMID: 33870146.
      View in: PubMed   Mentions:
    7. Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH). Hepatology. 2021 Feb 07. Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. PMID: 33550587.
      View in: PubMed   Mentions:    Fields:    
    8. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Rep. 2021 01 26; 34(4):108670. Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, He Y, Mondala P, Oliver I, Pham J, Ma W, Reynoso E, Ali S, Morris IJ, Diep R, Nasamran C, Xu G, Sasik R, Rosenthal SB, Birmingham A, Coso S, Pineda G, Crews L, Donohoe ME, Venter JC, Whisenant T, Mesa RA, Alexandrov LB, Fisch KM, Jamieson C. PMID: 33503434.
      View in: PubMed   Mentions: 2     Fields:    
    9. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. J Exp Med. 2020 12 07; 217(12). Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, Xu H. PMID: 32941599.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    10. Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. Cell. 2020 11 25; 183(5):1185-1201.e20. da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y, Zhang Y, Foox J, Zanello S, Crucian B, Wang D, Nugent A, Costa HA, Zwart SR, Schrepfer S, Elworth RAL, Sapoval N, Treangen T, MacKay M, Gokhale NS, Horner SM, Singh LN, Wallace DC, Willey JS, Schisler JC, Meller R, McDonald JT, Fisch KM, Hardiman G, Taylor D, Mason CE, Costes SV, Beheshti A. PMID: 33242417.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. Metabolomic profiles associated with a mouse model of antipsychotic-induced food intake and weight gain. Sci Rep. 2020 10 29; 10(1):18581. Zapata RC, Rosenthal SB, Fisch K, Dao K, Jain M, Osborn O. PMID: 33122657.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Interactome overlap between schizophrenia and cognition. Schizophr Res. 2020 08; 222:167-174. Koch E, Rosenthal B, Lundquist A, Chen CH, Kauppi K. PMID: 32546371.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859.
      View in: PubMed   Mentions: 879     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020 02 13; 5(3). Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, Roberts A, Zheng B, Kumar V, Zengler K, Pizzo DP, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob GF, Kisseleva T. PMID: 32051339.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    15. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Hepatol Commun. 2020 Apr; 4(4):606-626. Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, Brenner D, Kisseleva T. PMID: 32258954.
      View in: PubMed   Mentions:
    16. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. 2020 05; 158(6):1728-1744.e14. Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. PMID: 31982409.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    17. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. J Hepatol. 2020 05; 72(5):946-959. Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T. PMID: 31899206.
      View in: PubMed   Mentions: 12     Fields:    
    18. A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis. Sci Rep. 2019 08 15; 9(1):11879. Rosenthal SB, Bush KT, Nigam SK. PMID: 31417100.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    19. Ten simple rules for writing and sharing computational analyses in Jupyter Notebooks. PLoS Comput Biol. 2019 07; 15(7):e1007007. Rule A, Birmingham A, Zuniga C, Altintas I, Huang SC, Knight R, Moshiri N, Nguyen MH, Rosenthal SB, Pérez F, Rose PW. PMID: 31344036.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    20. Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease. Cell Rep. 2019 07 23; 28(4):1103-1116.e4. Canchi S, Raao B, Masliah D, Rosenthal SB, Sasik R, Fisch KM, De Jager PL, Bennett DA, Rissman RA. PMID: 31340147.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    21. Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. J Hepatol. 2019 09; 71(3):573-585. Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, Kisseleva T. PMID: 31071368.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    22. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019 04 18; 177(3):572-586.e22. Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. PMID: 30955884.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    23. On entropy and information in gene interaction networks. Bioinformatics. 2019 03 01; 35(5):815-822. Wallace ZS, Rosenthal SB, Fisch KM, Ideker T, Sasik R. PMID: 30102349.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Choline metabolite, trimethylamine N-oxide (TMAO), is associated with inflammation in psoriatic arthritis. Clin Exp Rheumatol. 2019 May-Jun; 37(3):481-484. Coras R, Kavanaugh A, Boyd T, Huynh D, Lagerborg KA, Xu YJ, Rosenthal SB, Jain M, Guma M. PMID: 30620278.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis. Arthritis Res Ther. 2018 08 03; 20(1):164. Narasimhan R, Coras R, Rosenthal SB, Sweeney SR, Lodi A, Tiziani S, Boyle D, Kavanaugh A, Guma M. PMID: 30075744.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48. Nat Commun. 2018 06 11; 9(1):2280. Velimezi G, Robinson-Garcia L, Muñoz-Martínez F, Wiegant WW, Ferreira da Silva J, Owusu M, Moder M, Wiedner M, Rosenthal SB, Fisch KM, Moffat J, Menche J, van Attikum H, Jackson SP, Loizou JI. PMID: 29891926.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    27. Characteristics Of Likely Precision Medicine Initiative Participants Drawn From A Large Blood Donor Population. Health Aff (Millwood). 2018 05; 37(5):786-792. Bloss CS, Stoler J, Schairer CE, Rosenthal SB, Cheung C, Rus HM, Block JL, Yang JJ, Morton D, Bixenman H, Wellis D. PMID: 29733733.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia. Am J Psychiatry. 2018 07 01; 175(7):674-682. Kauppi K, Rosenthal SB, Lo MT, Sanyal N, Jiang M, Abagyan R, McEvoy LK, Andreassen OA, Chen CH. PMID: 29495895.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Interactive network visualization in Jupyter notebooks: visJS2jupyter. Bioinformatics. 2018 01 01; 34(1):126-128. Rosenthal SB, Len J, Webster M, Gary A, Birmingham A, Fisch KM. PMID: 28968701.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    30. The evolution of distributed sensing and collective computation in animal populations. Elife. 2015 Dec 10; 4:e10955. Hein AM, Rosenthal SB, Hagstrom GI, Berdahl A, Torney CJ, Couzin ID. PMID: 26652003.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    31. Revealing the hidden networks of interaction in mobile animal groups allows prediction of complex behavioral contagion. Proc Natl Acad Sci U S A. 2015 Apr 14; 112(15):4690-5. Rosenthal SB, Twomey CR, Hartnett AT, Wu HS, Couzin ID. PMID: 25825752.
      View in: PubMed   Mentions: 91     Fields:    Translation:Animals
    32. Visual sensory networks and effective information transfer in animal groups. Curr Biol. 2013 Sep 09; 23(17):R709-11. Strandburg-Peshkin A, Twomey CR, Bode NW, Kao AB, Katz Y, Ioannou CC, Rosenthal SB, Torney CJ, Wu HS, Levin SA, Couzin ID. PMID: 24028946.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
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