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McEvoy, Linda

Title(s)Professor, Radiology
SchoolHealth Sciences
Phone858-822-6675
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    Collapse Biography 
    Collapse Education and Training
    University of Ottawa, Ottawa, ON, CanadaPhD1991Psychology & Neurosciences
    University of Calgary, Calgary, AB, CanadaBS (First Class Honors)1987Psychology

    Collapse Overview 
    Collapse Overview
    Linda McEvoy, PhD, is a Professor in the Department of Radiology and in the Department of Family Medicine and Public Health, Division of Epidemiology. She is co-director of the Women’s Health Center of Excellence and Associate Director of the Altman Clinical and Translational Research Institute Center for Life Course Research. Dr. McEvoy is a Principal Investigator on the Rancho Bernardo Study (RBS) of Healthy Aging, a longitudinal cohort study that was initiated in 1972. Dr. McEvoy’s current research focuses on elucidating behavioral and clinical moderators of trajectories of cognitive decline with age, and determining how these factors affect brain morphology and microstructure. She also studies biomarkers for early detection of Alzheimer’s disease

    Collapse Research 
    Collapse Research Activities and Funding
    Moderate alcohol use: risk or protective factor for age-related cognitive decline, mild cognitive impairment, and brain health in aging
    NIH/NIA R01AG062483Apr 15, 2019 - Jan 31, 2022
    Role: Principal Investigator
    Archiving the Rancho Bernardo Study of Healthy Aging
    NIH/NIA RF1AG054067Sep 1, 2016 - Jun 30, 2019
    Role: Principal Investigator
    Association of Alcohol and Nutrition with Cognition and Brain Structure in Aging
    NIH/NIAAA R01AA021187Sep 15, 2013 - Jun 30, 2018
    Role: Principal Investigator
    Structure and Functional Imaging of Age-Related Changes in Working Memory
    NIH/NIA K01AG029218Sep 30, 2007 - Aug 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ilango SD, McEvoy LK, Laughlin GA, Bergstrom J, Barrett-Connor E, Kritz-Silverstein D. Pregnancy history and cognitive aging among older women: the Rancho Bernardo Study. Menopause. 2019 Jul; 26(7):750-757. PMID: 30889095.
      View in: PubMed
    2. Lo MT, Kauppi K, Fan CC, Sanyal N, Reas ET, Sundar VS, Lee WC, Desikan RS, McEvoy LK, Chen CH. Identification of genetic heterogeneity of Alzheimer's disease across age. Neurobiol Aging. 2019 Mar 12. PMID: 30979435.
      View in: PubMed
    3. Franz CE, Hatton SN, Hauger RL, Kredlow MA, Dale AM, Eyler L, McEvoy LK, Fennema-Notestine C, Hagler D, Jacobson KC, McKenzie RE, Panizzon MS, Gustavson DE, Xian H, Toomey R, Beck A, Stevens S, Tu X, Lyons MJ, Kremen WS. Posttraumatic stress symptom persistence across 24 years: association with brain structures. Brain Imaging Behav. 2019 Mar 04. PMID: 30830577.
      View in: PubMed
    4. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Richard EL, Barrett-Connor E, McEvoy LK. Lifetime physical activity and late-life cognitive function: the Rancho Bernardo study. Age Ageing. 2019 Mar 01; 48(2):241-246. PMID: 30615048.
      View in: PubMed
    5. Alattar AA, Bergstrom J, Laughlin GA, Kritz-Silverstein D, Richard EL, Reas ET, Harris JP, Barrett-Connor E, McEvoy LK. Hearing impairment and cognitive decline in older, community-dwelling adults. J Gerontol A Biol Sci Med Sci. 2019 Feb 12. PMID: 30753308.
      View in: PubMed
    6. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. Effects of APOE on cognitive aging in community-dwelling older adults. Neuropsychology. 2019 Mar; 33(3):406-416. PMID: 30730162.
      View in: PubMed
    7. Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, Kukull WA, Tosun D, Weiner MW, Sperling RA, Bennett DA, Hyman BT, Andreassen OA, Dale AM, Desikan RS. Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Brain. 2019 02 01; 142(2):460-470. PMID: 30689776.
      View in: PubMed
    8. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, McEvoy LK. Physical Activity and Trajectories of Cognitive Change in Community-Dwelling Older Adults: The Rancho Bernardo Study. J Alzheimers Dis. 2019; 71(1):109-118. PMID: 31356211.
      View in: PubMed
    9. Vuoksimaa E, McEvoy LK, Holland D, Franz CE, Kremen WS. Modifying the minimum criteria for diagnosing amnestic MCI to improve prediction of brain atrophy and progression to Alzheimer's disease. Brain Imaging Behav. 2018 Dec 04. PMID: 30511118.
      View in: PubMed
    10. Elman JA, Panizzon MS, Gillespie NA, Hagler DJ, Fennema-Notestine C, Eyler LT, McEvoy LK, Neale MC, Lyons MJ, Franz CE, Dale AM, Kremen WS. Genetic architecture of hippocampal subfields on standard resolution MRI: How the parts relate to the whole. Hum Brain Mapp. 2019 Apr 01; 40(5):1528-1540. PMID: 30430703.
      View in: PubMed
    11. Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 Feb; 137(2):209-226. PMID: 30413934.
      View in: PubMed
    12. Gustavson DE, Hatton SN, Elman JA, Panizzon MS, Franz CE, Hagler DJ, Fennema-Notestine C, Eyler LT, McEvoy LK, Neale MC, Gillespie N, Dale AM, Lyons MJ, Kremen WS. Predominantly global genetic influences on individual white matter tract microstructure. Neuroimage. 2019 01 01; 184:871-880. PMID: 30296555.
      View in: PubMed
    13. Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. Microstructural brain changes track cognitive decline in mild cognitive impairment. Neuroimage Clin. 2018; 20:883-891. PMID: 30290303.
      View in: PubMed
    14. Richard EL, Laughlin GA, Kritz-Silverstein D, Reas ET, Barrett-Connor E, McEvoy LK. Dietary Patterns and Cognitive Function among Older Community-Dwelling Adults. Nutrients. 2018 Aug 14; 10(8). PMID: 30110945.
      View in: PubMed
    15. Kauppi K, Fan CC, McEvoy LK, Holland D, Tan CH, Chen CH, Andreassen OA, Desikan RS, Dale AM. Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease. Front Neurosci. 2018; 12:260. PMID: 29760643.
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    16. Mills PJ, McEvoy LK, Laughlin GA. Glyphosate Levels in Older Adults-Reply. JAMA. 2018 04 03; 319(13):1385. PMID: 29614176.
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    17. Hatton SN, Franz CE, Elman JA, Panizzon MS, Hagler DJ, Fennema-Notestine C, Eyler LT, McEvoy LK, Lyons MJ, Dale AM, Kremen WS. Negative fateful life events in midlife and advanced predicted brain aging. Neurobiol Aging. 2018 07; 67:1-9. PMID: 29609076.
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    18. Kauppi K, Rosenthal SB, Lo MT, Sanyal N, Jiang M, Abagyan R, McEvoy LK, Andreassen OA, Chen CH. Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia. Am J Psychiatry. 2018 07 01; 175(7):674-682. PMID: 29495895.
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    19. McEvoy LK, Fennema-Notestine C, Elman JA, Eyler LT, Franz CE, Hagler DJ, Hatton SN, Lyons MJ, Panizzon MS, Dale AM, Kremen WS. Alcohol intake and brain white matter in middle aged men: Microscopic and macroscopic differences. Neuroimage Clin. 2018; 18:390-398. PMID: 29487796.
      View in: PubMed
    20. Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 01; 135(1):85-93. PMID: 29177679.
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    21. Mills PJ, Kania-Korwel I, Fagan J, McEvoy LK, Laughlin GA, Barrett-Connor E. Excretion of the Herbicide Glyphosate in Older Adults Between 1993 and 2016. JAMA. 2017 10 24; 318(16):1610-1611. PMID: 29067413.
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    22. Elman JA, Panizzon MS, Hagler DJ, Eyler LT, Granholm EL, Fennema-Notestine C, Lyons MJ, McEvoy LK, Franz CE, Dale AM, Kremen WS. Task-evoked pupil dilation and BOLD variance as indicators of locus coeruleus dysfunction. Cortex. 2017 12; 97:60-69. PMID: 29096196.
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    23. Tan CH, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Polygenic hazard scores in preclinical Alzheimer disease. Ann Neurol. 2017 Sep; 82(3):484-488. PMID: 28940650.
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    24. Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Cross K, Loi RQ, Balachandra AR, Meloy MJ, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease. Alzheimers Res Ther. 2017 Aug 02; 9(1):55. PMID: 28764771.
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    25. Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T, Andreassen OA, Sharma M. Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. JAMA Neurol. 2017 07 01; 74(7):780-792. PMID: 28586827.
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    26. Devor A, Andreassen OA, Wang Y, Mäki-Marttunen T, Smeland OB, Fan CC, Schork AJ, Holland D, Thompson WK, Witoelar A, Chen CH, Desikan RS, McEvoy LK, Djurovic S, Greengard P, Svenningsson P, Einevoll GT, Dale AM. Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia. Mol Psychiatry. 2017 06; 22(6):792-801. PMID: 28348379.
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    27. Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 03; 14(3):e1002258. PMID: 28323831.
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    28. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. Effects of Sex and Education on Cognitive Change Over a 27-Year Period in Older Adults: The Rancho Bernardo Study. Am J Geriatr Psychiatry. 2017 Aug; 25(8):889-899. PMID: 28433548.
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    29. Gillespie NA, Neale MC, Hagler DJ, Eyler LT, Fennema-Notestine C, Franz CE, Lyons MJ, McEvoy LK, Dale AM, Panizzon MS, Kremen WS. Genetic and environmental influences on mean diffusivity and volume in subcortical brain regions. Hum Brain Mapp. 2017 05; 38(5):2589-2598. PMID: 28240386.
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    30. Karunamuni RA, Seibert TM, White NS, McEvoy L, Farid N, Brewer J, Dale AM, McDonald CR, Hattangadi-Gluth JA. Abnormalities in hippocampal volume of glioma patients prior to radiotherapy. Acta Oncol. 2017 Mar; 56(3):427-430. PMID: 28156177.
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    31. Richard EL, Kritz-Silverstein D, Laughlin GA, Fung TT, Barrett-Connor E, McEvoy LK. Alcohol Intake and Cognitively Healthy Longevity in Community-Dwelling Adults: The Rancho Bernardo Study. J Alzheimers Dis. 2017; 59(3):803-814. PMID: 28671111.
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    32. Rush TM, Kritz-Silverstein D, Laughlin GA, Fung TT, Barrett-Connor E, McEvoy LK. Association between Dietary Sodium Intake and Cognitive Function in Older Adults. J Nutr Health Aging. 2017; 21(3):276-283. PMID: 28244567.
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    33. Kritz-Silverstein D, Laughlin GA, McEvoy LK, Barrett-Connor E. Sex and Age Differences in the Association of Blood Pressure and Hypertension with Cognitive Function in the Elderly: The Rancho Bernardo Study. J Prev Alzheimers Dis. 2017; 4(3):165-173. PMID: 29182707.
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    34. Laughlin GA, Kritz-Silverstein D, Bergstrom J, Reas ET, Jassal SK, Barrett-Connor E, McEvoy LK. Vitamin D Insufficiency and Cognitive Function Trajectories in Older Adults: The Rancho Bernardo Study. J Alzheimers Dis. 2017; 58(3):871-883. PMID: 28505973.
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    35. Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Nat Genet. 2017 01; 49(1):152-156. PMID: 27918536.
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    36. Elman JA, Panizzon MS, Hagler DJ, Fennema-Notestine C, Eyler LT, Gillespie NA, Neale MC, Lyons MJ, Franz CE, McEvoy LK, Dale AM, Kremen WS. Genetic and environmental influences on cortical mean diffusivity. Neuroimage. 2017 Feb 01; 146:90-99. PMID: 27864081.
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    37. Fennema-Notestine C, McEvoy LK, Notestine R, Panizzon MS, Yau WW, Franz CE, Lyons MJ, Eyler LT, Neale MC, Xian H, McKenzie RE, Kremen WS. White matter disease in midlife is heritable, related to hypertension, and shares some genetic influence with systolic blood pressure. Neuroimage Clin. 2016; 12:737-745. PMID: 27790395.
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    38. Reas ET, Laughlin GA, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. Moderate, Regular Alcohol Consumption is Associated with Higher Cognitive Function in Older Community-Dwelling Adults. J Prev Alzheimers Dis. 2016 Sep; 3(2):105-113. PMID: 27184039.
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    39. Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 06 01; 73(6):691-7. PMID: 27088644.
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    40. Wang Y, Bos SD, Harbo HF, Thompson WK, Schork AJ, Bettella F, Witoelar A, Lie BA, Li W, McEvoy LK, Djurovic S, Desikan RS, Dale AM, Andreassen OA. Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Mult Scler. 2016 12; 22(14):1783-1793. PMID: 26920376.
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    41. Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA. Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci. PLoS One. 2015; 10(12):e0144531. PMID: 26695485.
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    42. Bellettiere J, Kritz-Silverstein D, Laughlin GA, LaCroix AZ, McEvoy LK, Barrett-Connor E. Relation of Depressive Symptoms With Coronary Artery Calcium Determined by Electron-Beam Computed Tomography (from the Rancho Bernardo Study). Am J Cardiol. 2016 Feb 01; 117(3):325-32. PMID: 26747734.
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    43. Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM. Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate. PLoS Genet. 2015 Nov; 11(11):e1005544. PMID: 26540268.
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    44. LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS, Dale AM, Andreassen OA. Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors. Circ Res. 2016 Jan 08; 118(1):83-94. PMID: 26487741.
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    45. Docherty AR, Sawyers CK, Panizzon MS, Neale MC, Eyler LT, Fennema-Notestine C, Franz CE, Chen CH, McEvoy LK, Verhulst B, Tsuang MT, Kremen WS. Genetic network properties of the human cortex based on regional thickness and surface area measures. Front Hum Neurosci. 2015; 9:440. PMID: 26347632.
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    46. Jack CR, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M. Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. PMID: 26194310.
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    47. McEvoy LK, Fennema-Notestine C, Eyler LT, Franz CE, Hagler DJ, Lyons MJ, Panizzon MS, Rinker DA, Dale AM, Kremen WS. Hypertension-related alterations in white matter microstructure detectable in middle age. Hypertension. 2015 Aug; 66(2):317-23. PMID: 26056337.
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    48. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM. Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms. PLoS One. 2015; 10(5):e0128048. PMID: 25978331.
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    49. Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 09; 131(23):2061-2069. PMID: 25862742.
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    50. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Mills I, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM. Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS One. 2015; 10(4):e0123057. PMID: 25853426.
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    51. Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M, Choi SH, DeStefano A, Ikram MA, Bis JC, Smith A, Fitzpatrick AL, Launer L, van Duijn C, Seshadri S, Ulstein ID, Aarsland D, Fladby T, Djurovic S, Hyman BT, Snaedal J, Stefansson H, Stefansson K, Gasser T, Andreassen OA, Dale AM. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry. 2015 Dec; 20(12):1588-95. PMID: 25687773.
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    52. Oania R, McEvoy LK. Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment. Age Ageing. 2015 Jan; 44(1):53-8. PMID: 25349150.
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    53. Fjell AM, McEvoy L, Holland D, Dale AM, Walhovd KB. What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus. Prog Neurobiol. 2014 Jun; 117:20-40. PMID: 24548606.
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    54. Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. The role of clusterin in amyloid-ß-associated neurodegeneration. JAMA Neurol. 2014 Feb; 71(2):180-7. PMID: 24378367.
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    55. Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P, McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Mol Psychiatry. 2015 Feb; 20(2):207-14. PMID: 24468824.
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    56. Laughlin GA, McEvoy LK, Barrett-Connor E, Daniels LB, Ix JH. Fetuin-A, a new vascular biomarker of cognitive decline in older adults. Clin Endocrinol (Oxf). 2014 Jul; 81(1):134-40. PMID: 24325554.
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    57. Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM. Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes. Hypertension. 2014 Apr; 63(4):819-26. PMID: 24396023.
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    58. Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. Heart fatty acid binding protein and Aß-associated Alzheimer's neurodegeneration. Mol Neurodegener. 2013 Oct 02; 8:39. PMID: 24088526.
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    59. Chang YL, Fennema-Notestine C, Holland D, McEvoy LK, Stricker NH, Salmon DP, Dale AM, Bondi MW. APOE interacts with age to modify rate of decline in cognitive and brain changes in Alzheimer's disease. Alzheimers Dement. 2014 May; 10(3):336-48. PMID: 23896613.
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    60. McEvoy LK, Kritz-Silverstein D, Barrett-Connor E, Bergstrom J, Laughlin GA. Changes in alcohol intake and their relationship with health status over a 24-year follow-up period in community-dwelling older adults. J Am Geriatr Soc. 2013 Aug; 61(8):1303-8. PMID: 23865905.
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    61. Holland D, Desikan RS, Dale AM, McEvoy LK. Higher rates of decline for women and apolipoprotein E epsilon4 carriers. AJNR Am J Neuroradiol. 2013 Dec; 34(12):2287-93. PMID: 23828104.
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    62. Fjell AM, McEvoy L, Holland D, Dale AM, Walhovd KB. Brain changes in older adults at very low risk for Alzheimer's disease. J Neurosci. 2013 May 08; 33(19):8237-42. PMID: 23658162.
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    63. Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM. Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet. 2013 Apr; 9(4):e1003455. PMID: 23637625.
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    64. Andreassen OA, Djurovic S, Thompson WK, Schork AJ, Kendler KS, O'Donovan MC, Rujescu D, Werge T, van de Bunt M, Morris AP, McCarthy MI, Roddey JC, McEvoy LK, Desikan RS, Dale AM. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am J Hum Genet. 2013 Feb 07; 92(2):197-209. PMID: 23375658.
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    65. Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC. Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2012 Dec 01; 35(12):1593-602. PMID: 23204602.
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    66. Holland D, McEvoy LK, Desikan RS, Dale AM. Enrichment and stratification for predementia Alzheimer disease clinical trials. PLoS One. 2012; 7(10):e47739. PMID: 23082203.
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    67. Desikan RS, McEvoy LK, Holland D, Thompson WK, Brewer JB, Aisen PS, Andreassen OA, Hyman BT, Sperling RA, Dale AM. Apolipoprotein E epsilon4 does not modulate amyloid-ß-associated neurodegeneration in preclinical Alzheimer disease. AJNR Am J Neuroradiol. 2013 Mar; 34(3):505-10. PMID: 22976236.
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    68. Kemmotsu N, Girard HM, Kucukboyaci NE, McEvoy LK, Hagler DJ, Dale AM, Halgren E, McDonald CR. Age-related changes in the neurophysiology of language in adults: relationship to regional cortical thinning and white matter microstructure. J Neurosci. 2012 Aug 29; 32(35):12204-13. PMID: 22933802.
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    71. McEvoy LK, Brewer JB. Biomarkers for the clinical evaluation of the cognitively impaired elderly: amyloid is not enough. Imaging Med. 2012 Jun; 4(3):343-357. PMID: 23420460.
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    72. Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM. Amyloid-ß--associated clinical decline occurs only in the presence of elevated P-tau. Arch Neurol. 2012 Jun; 69(6):709-13. PMID: 22529247.
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    73. Murphy EA, Roddey JC, McEvoy LK, Holland D, Hagler DJ, Dale AM, Brewer JB. CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner. Brain Imaging Behav. 2012 Mar; 6(1):16-26. PMID: 21892657.
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    74. McEvoy LK, Laughlin GA, Barrett-Connor E, Bergstrom J, Kritz-Silverstein D, Der-Martirosian C, von Mühlen D. Metabolic syndrome and 16-year cognitive decline in community-dwelling older adults. Ann Epidemiol. 2012 May; 22(5):310-7. PMID: 22285865.
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    76. Desikan RS, McEvoy LK, Thompson WK, Holland D, Roddey JC, Blennow K, Aisen PS, Brewer JB, Hyman BT, Dale AM. Amyloid-ß associated volume loss occurs only in the presence of phospho-tau. Ann Neurol. 2011 Oct; 70(4):657-61. PMID: 22002658.
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    77. Heister D, Brewer JB, Magda S, Blennow K, McEvoy LK. Predicting MCI outcome with clinically available MRI and CSF biomarkers. Neurology. 2011 Oct 25; 77(17):1619-28. PMID: 21998317.
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    78. Laughlin GA, McEvoy LK, von Mühlen D, Daniels LB, Kritz-Silverstein D, Bergstrom J, Cummins K, Der-Martirosian C, Jassal SK, Barrett-Connor E. Sex differences in the association of Framingham Cardiac Risk Score with cognitive decline in community-dwelling elders without clinical heart disease. Psychosom Med. 2011 Oct; 73(8):683-9. PMID: 21949428.
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    79. Holland D, McEvoy LK, Dale AM. Unbiased comparison of sample size estimates from longitudinal structural measures in ADNI. Hum Brain Mapp. 2012 Nov; 33(11):2586-602. PMID: 21830259.
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    80. McEvoy LK, Holland D, Hagler DJ, Fennema-Notestine C, Brewer JB, Dale AM. Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis. Radiology. 2011 Jun; 259(3):834-43. PMID: 21471273.
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    81. Chang YL, Bondi MW, McEvoy LK, Fennema-Notestine C, Salmon DP, Galasko D, Hagler DJ, Dale AM. Global clinical dementia rating of 0.5 in MCI masks variability related to level of function. Neurology. 2011 Feb 15; 76(7):652-9. PMID: 21321338.
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    82. Gevins A, Ilan AB, Jiang A, Chan CS, Gelinas D, Smith ME, McEvoy LK, Schwager E, Padilla M, Davis Z, Meador KJ, Patterson J, O'Hara R. A method to combine cognitive and neurophysiological assessments of the elderly. Dement Geriatr Cogn Disord. 2011; 31(1):7-19. PMID: 21109739.
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    83. McEvoy LK, Brewer JB. Quantitative structural MRI for early detection of Alzheimer's disease. Expert Rev Neurother. 2010 Nov; 10(11):1675-88. PMID: 20977326.
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    84. Karow DS, McEvoy LK, Fennema-Notestine C, Hagler DJ, Jennings RG, Brewer JB, Hoh CK, Dale AM. Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease. Radiology. 2010 Sep; 256(3):932-42. PMID: 20720076.
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    85. Murphy EA, Holland D, Donohue M, McEvoy LK, Hagler DJ, Dale AM, Brewer JB. Six-month atrophy in MTL structures is associated with subsequent memory decline in elderly controls. Neuroimage. 2010 Dec; 53(4):1310-7. PMID: 20633660.
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    86. Gevins A, Smith ME, McEvoy LK, Ilan AB, Chan CS, Jiang A, Sam-Vargas L, Abraham G. A cognitive and neurophysiological test of change from an individual's baseline. Clin Neurophysiol. 2011 Jan; 122(1):114-20. PMID: 20619727.
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    87. McEvoy LK, Edland SD, Holland D, Hagler DJ, Roddey JC, Fennema-Notestine C, Salmon DP, Koyama AK, Aisen PS, Brewer JB, Dale AM. Neuroimaging enrichment strategy for secondary prevention trials in Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):269-77. PMID: 20683184.
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    88. McDonald CR, Gharapetian L, McEvoy LK, Fennema-Notestine C, Hagler DJ, Holland D, Dale AM. Relationship between regional atrophy rates and cognitive decline in mild cognitive impairment. Neurobiol Aging. 2012 Feb; 33(2):242-53. PMID: 20471718.
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    89. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM. CSF biomarkers in prediction of cerebral and clinical change in mild cognitive impairment and Alzheimer's disease. J Neurosci. 2010 Feb 10; 30(6):2088-101. PMID: 20147537.
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    90. Walhovd KB, Fjell AM, Brewer J, McEvoy LK, Fennema-Notestine C, Hagler DJ, Jennings RG, Karow D, Dale AM. Combining MR imaging, positron-emission tomography, and CSF biomarkers in the diagnosis and prognosis of Alzheimer disease. AJNR Am J Neuroradiol. 2010 Feb; 31(2):347-54. PMID: 20075088.
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    91. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Blennow K, Brewer JB, Dale AM. Brain atrophy in healthy aging is related to CSF levels of Aß1-42. Cereb Cortex. 2010 Sep; 20(9):2069-79. PMID: 20051356.
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    92. Chang YL, Bondi MW, Fennema-Notestine C, McEvoy LK, Hagler DJ, Jacobson MW, Dale AM. Brain substrates of learning and retention in mild cognitive impairment diagnosis and progression to Alzheimer's disease. Neuropsychologia. 2010 Apr; 48(5):1237-47. PMID: 20034503.
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    93. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM. One-year brain atrophy evident in healthy aging. J Neurosci. 2009 Dec 02; 29(48):15223-31. PMID: 19955375.
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    94. Swann N, Tandon N, Canolty R, Ellmore TM, McEvoy LK, Dreyer S, DiSano M, Aron AR. Intracranial EEG reveals a time- and frequency-specific role for the right inferior frontal gyrus and primary motor cortex in stopping initiated responses. J Neurosci. 2009 Oct 07; 29(40):12675-85. PMID: 19812342.
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    96. Chang YL, Jacobson MW, Fennema-Notestine C, Hagler DJ, Jennings RG, Dale AM, McEvoy LK. Level of executive function influences verbal memory in amnestic mild cognitive impairment and predicts prefrontal and posterior cingulate thickness. Cereb Cortex. 2010 Jun; 20(6):1305-13. PMID: 19776343.
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    97. McDonald CR, McEvoy LK, Gharapetian L, Fennema-Notestine C, Hagler DJ, Holland D, Koyama A, Brewer JB, Dale AM. Regional rates of neocortical atrophy from normal aging to early Alzheimer disease. Neurology. 2009 Aug 11; 73(6):457-65. PMID: 19667321.
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    98. Perry ME, McDonald CR, Hagler DJ, Gharapetian L, Kuperman JM, Koyama AK, Dale AM, McEvoy LK. White matter tracts associated with set-shifting in healthy aging. Neuropsychologia. 2009 Nov; 47(13):2835-42. PMID: 19540862.
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    99. McEvoy LK, Fennema-Notestine C, Roddey JC, Hagler DJ, Holland D, Karow DS, Pung CJ, Brewer JB, Dale AM. Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment. Radiology. 2009 Apr; 251(1):195-205. PMID: 19201945.
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    101. Fennema-Notestine C, McEvoy LK, Hagler DJ, Jacobson MW, Dale AM. Structural neuroimaging in the detection and prognosis of pre-clinical and early AD. Behav Neurol. 2009; 21(1):3-12. PMID: 19847040.
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    102. Walhovd KB, Fjell AM, Dale AM, McEvoy LK, Brewer J, Karow DS, Salmon DP, Fennema-Notestine C. Multi-modal imaging predicts memory performance in normal aging and cognitive decline. Neurobiol Aging. 2010 Jul; 31(7):1107-21. PMID: 18838195.
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    103. Meador KJ, Gevins A, Loring DW, McEvoy LK, Ray PG, Smith ME, Motamedi GK, Evans BM, Baum C. Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam. Neurology. 2007 Nov 27; 69(22):2076-84. PMID: 18040014.
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    104. Kushida CA, Nichols DA, Quan SF, Goodwin JL, White DP, Gottlieb DJ, Walsh JK, Schweitzer PK, Guilleminault C, Simon RD, Leary EB, Hyde PR, Holmes TH, Bloch DA, Green S, McEvoy LK, Gevins A, Dement WC. The Apnea Positive Pressure Long-term Efficacy Study (APPLES): rationale, design, methods, and procedures. J Clin Sleep Med. 2006 Jul 15; 2(3):288-300. PMID: 17561541.
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    105. McEvoy LK, Smith ME, Fordyce M, Gevins A. Characterizing impaired functional alertness from diphenhydramine in the elderly with performance and neurophysiologic measures. Sleep. 2006 Jul; 29(7):957-66. PMID: 16895264.
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    106. Kelleher MO, McEvoy L, Nagaria J, Kamel M, Bolger C. Image-guided transarticular atlanto-axial screw fixation. Int J Med Robot. 2006 Jun; 2(2):154-60. PMID: 17520626.
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    107. Smith ME, Gevins A, McEvoy LK, Meador KJ, Ray PG, Gilliam F. Distinct cognitive neurophysiologic profiles for lamotrigine and topiramate. Epilepsia. 2006 Apr; 47(4):695-703. PMID: 16650135.
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    108. Smith ME, McEvoy LK, Gevins A. The impact of moderate sleep loss on neurophysiologic signals during working-memory task performance. Sleep. 2002 Nov 01; 25(7):784-94. PMID: 12405615.
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    109. Chung SS, McEvoy LK, Smith ME, Gevins A, Meador K, Laxer KD. Task-related EEG and ERP changes without performance impairment following a single dose of phenytoin. Clin Neurophysiol. 2002 Jun; 113(6):806-14. PMID: 12048040.
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    110. Gevins A, Smith ME, McEvoy LK. Tracking the cognitive pharmacodynamics of psychoactive substances with combinations of behavioral and neurophysiological measures. Neuropsychopharmacology. 2002 Jan; 26(1):27-39. PMID: 11751030.
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    111. McEvoy LK, Pellouchoud E, Smith ME, Gevins A. Neurophysiological signals of working memory in normal aging. Brain Res Cogn Brain Res. 2001 Jun; 11(3):363-76. PMID: 11339986.
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    113. Gevins A, Smith ME, McEvoy LK, Leong H, Le J. Electroencephalographic imaging of higher brain function. Philos Trans R Soc Lond B Biol Sci. 1999 Jul 29; 354(1387):1125-33. PMID: 10466140.
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    114. Gevins A, Le J, Leong H, McEvoy LK, Smith ME. Deblurring. J Clin Neurophysiol. 1999 May; 16(3):204-13. PMID: 10426404.
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    115. Pellouchoud E, Smith ME, McEvoy L, Gevins A. Mental effort-related EEG modulation during video-game play: comparison between juvenile subjects with epilepsy and normal control subjects. Epilepsia. 1999; 40 Suppl 4:38-43. PMID: 10487172.
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    116. Smith ME, McEvoy LK, Gevins A. Neurophysiological indices of strategy development and skill acquisition. Brain Res Cogn Brain Res. 1999 Jan; 7(3):389-404. PMID: 9838200.
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    117. McEvoy LK, Smith ME, Gevins A. Dynamic cortical networks of verbal and spatial working memory: effects of memory load and task practice. Cereb Cortex. 1998 Oct-Nov; 8(7):563-74. PMID: 9823478.
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    119. Gevins A, Smith ME, McEvoy L, Yu D. High-resolution EEG mapping of cortical activation related to working memory: effects of task difficulty, type of processing, and practice. Cereb Cortex. 1997 Jun; 7(4):374-85. PMID: 9177767.
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    120. McEvoy L, Levänen S, Loveless N. Temporal characteristics of auditory sensory memory: neuromagnetic evidence. Psychophysiology. 1997 May; 34(3):308-16. PMID: 9175445.
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    121. Raij T, McEvoy L, Mäkelä JP, Hari R. Human auditory cortex is activated by omissions of auditory stimuli. Brain Res. 1997 Jan 16; 745(1-2):134-43. PMID: 9037402.
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    122. Mäkelä JP, McEvoy L. Auditory evoked fields to illusory sound source movements. Exp Brain Res. 1996 Aug; 110(3):446-54. PMID: 8871103.
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    123. Levänen S, Loveless N, McEvoy L. Persisting versus sustained neural activity: effects on transient N100m response. Neuroreport. 1996 May 31; 7(8):1389-92. PMID: 8856682.
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    124. Gevins A, Smith ME, Le J, Leong H, Bennett J, Martin N, McEvoy L, Du R, Whitfield S. High resolution evoked potential imaging of the cortical dynamics of human working memory. Electroencephalogr Clin Neurophysiol. 1996 Apr; 98(4):327-48. PMID: 8641154.
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    125. Levänen S, Ahonen A, Hari R, McEvoy L, Sams M. Deviant auditory stimuli activate human left and right auditory cortex differently. Cereb Cortex. 1996 Mar-Apr; 6(2):288-96. PMID: 8670657.
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    128. Imada T, Hari R, Loveless N, McEvoy L, Sams M. Determinants of the auditory mismatch response. Electroencephalogr Clin Neurophysiol. 1993 Sep; 87(3):144-53. PMID: 7691541.
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    129. Forss N, Mäkelä JP, McEvoy L, Hari R. Temporal integration and oscillatory responses of the human auditory cortex revealed by evoked magnetic fields to click trains. Hear Res. 1993 Jun; 68(1):89-96. PMID: 8376218.
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    130. Sams M, Hämäläinen M, Hari R, McEvoy L. Human auditory cortical mechanisms of sound lateralization: I. Interaural time differences within sound. Hear Res. 1993 May; 67(1-2):89-97. PMID: 8340282.
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    131. McEvoy L, Hari R, Imada T, Sams M. Human auditory cortical mechanisms of sound lateralization: II. Interaural time differences at sound onset. Hear Res. 1993 May; 67(1-2):98-109. PMID: 8340283.
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    132. Levänen S, Hari R, McEvoy L, Sams M. Responses of the human auditory cortex to changes in one versus two stimulus features. Exp Brain Res. 1993; 97(1):177-83. PMID: 8131828.
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    133. McEvoy LK, Picton TW, Champagne SC. The timing of the processes underlying lateralization: psychophysical and evoked potential measures. Ear Hear. 1991 Dec; 12(6):389-98. PMID: 1797606.
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    134. Compton WM, Helzer JE, Hwu HG, Yeh EK, McEvoy L, Tipp JE, Spitznagel EL. New methods in cross-cultural psychiatry: psychiatric illness in Taiwan and the United States. Am J Psychiatry. 1991 Dec; 148(12):1697-704. PMID: 1957932.
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    135. McEvoy LK, Picton TW, Champagne SC. Effects of stimulus parameters on human evoked potentials to shifts in the lateralization of a noise. Audiology. 1991; 30(5):286-302. PMID: 1793389.
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    136. Picton TW, McEvoy LK, Champagne SC. Human evoked potentials and the lateralization of a sound. Acta Otolaryngol Suppl. 1991; 491:139-43; discussion 144. PMID: 1814145.
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