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Nicholas Schork

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address9500 Gilman Drive #0603
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Integrative Resource to Develop Translational Strategies to Promote Longevity
    NIH/NIA U24AG051129Sep 15, 2015 - May 31, 2020
    Role: Principal Investigator
    The Bipolar Genome Study
    NIH/NIMH R01MH094483Jul 1, 2012 - Apr 30, 2015
    Role: Principal Investigator
    Functional genomic tools for in vivo study of P. vivax
    NIH/NIAID R21AI085374Jun 15, 2010 - Nov 30, 2012
    Role: Principal Investigator
    Biomarkers of Autism at 12 months: From Brain Overgrowth to Genes
    NIH/NIMH P50MH081755Aug 6, 2007 - Jun 30, 2014
    Role: Co-Investigator
    Genomics for Transplantation: Discovery and Biomarkers
    NIH U19AI063603Sep 1, 2004 - Aug 31, 2016
    Role: Co-Investigator
    FAMILY BLOOD PRESSURE PROGRAM
    NIH/NHLBI U01HL064777Sep 29, 2000 - Jun 30, 2005
    Role: Principal Investigator
    Sympathetic Neuroeffector Junctions &Blood Pressure
    NIH P01HL058120Jun 1, 1999 - May 31, 2012
    Role: Co-Investigator
    High Performance Computing for Biomedical Research
    NIH P41RR006009Sep 1, 1990 - Jul 31, 2013
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rangan AV, McGrouther CC, Kelsoe J, Schork N, Stahl E, Zhu Q, Krishnan A, Yao V, Troyanskaya O, Bilaloglu S, Raghavan P, Bergen S, Jureus A, Landen M. A loop-counting method for covariate-corrected low-rank biclustering of gene-expression and genome-wide association study data. PLoS Comput Biol. 2018 May 14; 14(5):e1006105. PMID: 29758032.
      View in: PubMed
    2. Schork N. The big data revolution and human genetics. Hum Mol Genet. 2018 May 01; 27(R1):R1. PMID: 29672687.
      View in: PubMed
    3. Choi Y, Chan AP, Kirkness E, Telenti A, Schork N. Comparison of phasing strategies for whole human genomes. PLoS Genet. 2018 Apr; 14(4):e1007308. PMID: 29621242.
      View in: PubMed
    4. Ryu S, Han J, Norden-Krichmar TM, Schork N, Suh Y. Effective discovery of rare variants by pooled target capture sequencing: A comparative analysis with individually indexed target capture sequencing. Mutat Res. 2018 Mar 30; 809:24-31. PMID: 29677560.
      View in: PubMed
    5. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, Loomba R. Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2018 Mar 23. PMID: 29572891.
      View in: PubMed
    6. Bakken T, Cowell L, Aevermann BD, Novotny M, Hodge R, Miller JA, Lee A, Chang I, McCorrison J, Pulendran B, Qian Y, Schork N, Lasken RS, Lein ES, Scheuermann RH. Cell type discovery and representation in the era of high-content single cell phenotyping. BMC Bioinformatics. 2017 Dec 21; 18(Suppl 17):559. PMID: 29322913.
      View in: PubMed
    7. Ding KF, Petricoin EF, Finlay D, Yin H, Hendricks WPD, Sereduk C, Kiefer J, Sekulic A, LoRusso PM, Vuori K, Trent JM, Schork N. Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis. Oncotarget. 2018 Jan 12; 9(4):5044-5057. PMID: 29435161.
      View in: PubMed
    8. Scelzo A, Di Somma S, Antonini P, Montross LP, Schork N, Brenner D, Jeste DV. Mixed-methods quantitative-qualitative study of 29 nonagenarians and centenarians in rural Southern Italy: focus on positive psychological traits. Int Psychogeriatr. 2018 Jan; 30(1):31-38. PMID: 29229012.
      View in: PubMed
    9. Schork N, Goetz LH. Single-Subject Studies in Translational Nutrition Research. Annu Rev Nutr. 2017 08 21; 37:395-422. PMID: 28715990.
      View in: PubMed
    10. Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, Hemming A, Andrews B, Salotti J, Richards L, Brenner DA, Sirlin CB, Loomba R. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. J Clin Invest. 2017 Jun 30; 127(7):2697-2704. PMID: 28628033.
      View in: PubMed
    11. Buckley AR, Standish KA, Bhutani K, Ideker T, Lasken RS, Carter H, Harismendy O, Schork N. Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls. BMC Genomics. 2017 06 12; 18(1):458. PMID: 28606096.
      View in: PubMed
    12. Standish KA, Huang CC, Curran ME, Schork N. Comprehensive analysis of treatment response phenotypes in rheumatoid arthritis for pharmacogenetic studies. Arthritis Res Ther. 2017 May 12; 19(1):90. PMID: 28494788.
      View in: PubMed
    13. Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5. PMID: 28467925.
      View in: PubMed
    14. Jia P, Zhao Z, Hulgan T, Bush WS, Samuels DC, Bloss CS, Heaton RK, Ellis RJ, Schork N, Marra CM, Collier AC, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, McCutchan JA, Barnholtz-Sloan JS, Franklin DR, Rosario D, Letendre SL, Grant I, Kallianpur AR. Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):413-426. PMID: 28447399.
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    15. Ding KF, Finlay D, Yin H, Hendricks WPD, Sereduk C, Kiefer J, Sekulic A, LoRusso PM, Vuori K, Trent JM, Schork N. Analysis of variability in high throughput screening data: applications to melanoma cell lines and drug responses. Oncotarget. 2017 Apr 25; 8(17):27786-27799. PMID: 28212541.
      View in: PubMed
    16. Iacoviello BM, Steinerman JR, Klein DB, Silver TL, Berger AG, Luo SX, Schork N. Clickotine, A Personalized Smartphone App for Smoking Cessation: Initial Evaluation. JMIR Mhealth Uhealth. 2017 Apr 25; 5(4):e56. PMID: 28442453.
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    17. Peng Q, Schork N, Wilhelmsen KC, Ehlers CL. Whole genome sequence association and ancestry-informed polygenic profile of EEG alpha in a Native American population. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):435-450. PMID: 28436151.
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    18. Long T, Hicks M, Yu HC, Biggs WH, Kirkness EF, Menni C, Zierer J, Small KS, Mangino M, Messier H, Brewerton S, Turpaz Y, Perkins BA, Evans AM, Miller LA, Guo L, Caskey CT, Schork N, Garner C, Spector TD, Venter JC, Telenti A. Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites. Nat Genet. 2017 Apr; 49(4):568-578. PMID: 28263315.
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    19. Li Q, Wineinger NE, Fu DJ, Libiger O, Alphs L, Savitz A, Gopal S, Cohen N, Schork N. Genome-wide association study of paliperidone efficacy. Pharmacogenet Genomics. 2017 Jan; 27(1):7-18. PMID: 27846195.
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    20. Aevermann B, McCorrison J, Venepally P, Hodge R, Bakken T, Miller J, Novotny M, Tran DN, Diezfuertes F, Christiansen L, Zhang F, Steemers F, Lasken RS, Lein ED, Schork N, Scheuermann RH. PRODUCTION OF A PRELIMINARY QUALITY CONTROL PIPELINE FOR SINGLE NUCLEI RNA-SEQ AND ITS APPLICATION IN THE ANALYSIS OF CELL TYPE DIVERSITY OF POST-MORTEM HUMAN BRAIN NEOCORTEX. Pac Symp Biocomput. 2017; 22:564-575. PMID: 27897007.
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    21. Benyamin B, Maihofer AX, Schork AJ, Hamilton BA, Rao F, Schmid-Schönbein GW, Zhang K, Mahata M, Stridsberg M, Schork N, Biswas N, Hook VY, Wei Z, Montgomery GW, Martin NG, Nievergelt CM, Whitfield JB, O'Connor DT. Identification of novel loci affecting circulating chromogranins and related peptides. Hum Mol Genet. 2017 01 01; 26(1):233-242. PMID: 28011710.
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    22. Boeldt DL, Cheung C, Ariniello L, Darst BF, Topol S, Schork N, Philis-Tsimikas A, Torkamani A, Fortmann AL, Bloss CS. Patient perspectives on whole-genome sequencing for undiagnosed diseases. Per Med. 2017 Jan; 14(1):17-25. PMID: 29749824.
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    23. Yin X, Wineinger NE, Wang K, Yue W, Norgren N, Wang L, Yao W, Jiang X, Wu B, Cui Y, Shen C, Cheng H, Zhou F, Chen G, Zuo X, Zheng X, Fan X, Wang H, Wang L, Lee J, Lam M, Tai ES, Zhang Z, Huang Q, Sun L, Xu J, Yang S, Wilhelmsen KC, Liu J, Schork N, Zhang X. Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population. J Psychiatry Neurosci. 2016 10; 41(6):413-421. PMID: 27091718.
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    24. Evans DS, Avery CL, Nalls MA, Li G, Barnard J, Smith EN, Tanaka T, Butler AM, Buxbaum SG, Alonso A, Arking DE, Berenson GS, Bis JC, Buyske S, Carty CL, Chen W, Chung MK, Cummings SR, Deo R, Eaton CB, Fox ER, Heckbert SR, Heiss G, Hindorff LA, Hsueh WC, Isaacs A, Jamshidi Y, Kerr KF, Liu F, Liu Y, Lohman KK, Magnani JW, Maher JF, Mehra R, Meng YA, Musani SK, Newton-Cheh C, North KE, Psaty BM, Redline S, Rotter JI, Schnabel RB, Schork N, Shohet RV, Singleton AB, Smith JD, Soliman EZ, Srinivasan SR, Taylor HA, Van Wagoner DR, Wilson JG, Young T, Zhang ZM, Zonderman AB, Evans MK, Ferrucci L, Murray SS, Tranah GJ, Whitsel EA, Reiner AP. Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. Hum Mol Genet. 2016 10 01; 25(19):4350-4368. PMID: 27577874.
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    25. Peng Q, Schork N, Bartsch H, Lo MT, Panizzon MS. Conservation of Distinct Genetically-Mediated Human Cortical Pattern. PLoS Genet. 2016 07; 12(7):e1006143. PMID: 27459196.
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    26. Cui J, Chen CH, Lo MT, Schork N, Bettencourt R, Gonzalez MP, Bhatt A, Hooker J, Shaffer K, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. Hepatology. 2016 11; 64(5):1547-1558. PMID: 27315352.
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    27. Cayer DM, Nazor KL, Schork N. Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine. Hum Mol Genet. 2016 Oct 01; 25(R2):R182-R189. PMID: 27439388.
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    28. Kawakatsu T, Huang SC, Jupe F, Sasaki E, Schmitz RJ, Urich MA, Castanon R, Nery JR, Barragan C, He Y, Chen H, Dubin M, Lee CR, Wang C, Bemm F, Becker C, O'Neil R, O'Malley RC, Quarless DX. Epigenomic Diversity in a Global Collection of Arabidopsis thaliana Accessions. Cell. 2016 Jul 14; 166(2):492-505. PMID: 27419873.
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    29. Song Y, Shi Y, Carland TM, Lian S, Sasaki T, Schork N, Head SR, Kishi S, Schimmel P. p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. Proc Natl Acad Sci U S A. 2016 07 26; 113(30):8460-5. PMID: 27402763; PMCID: PMC4968768 [Available on 01/26/17].
    30. Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, Berrettini WH, Bhattacharjee AK, Biernacka JM, Birner A, Bloss CS, Brichant-Petitjean C, Bui ET, Byerley W, Cervantes P, Chillotti C, Cichon S, Colom F, Coryell W, Craig DW, Cruceanu C, Czerski PM, Davis T, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Edenberg HJ, Étain B, Falkai P, Foroud T, Forstner AJ, Frisén L, Frye MA, Fullerton JM, Gard S, Garnham JS, Gershon ES, Goes FS, Greenwood TA, Grigoroiu-Serbanescu M, Hauser J, Heilbronner U, Heilmann-Heimbach S, Herms S, Hipolito M, Hitturlingappa S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Koller DL, König B, Lackner N, Laje G, Lang M, Lavebratt C, Lawson WB, Leboyer M, Leckband SG, Liu C, Maaser A, Mahon PB, Maier W, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McInnis MG, McKinney R, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Mühleisen TW, Nievergelt CM, Nöthen MM, Novák T, Nurnberger JI, Nwulia EA, Ösby U, Pfennig A, Potash JB, Propping P, Reif A, Reininghaus E, Rice J, Rietschel M, Rouleau GA, Rybakowski JK, Schalling M, Scheftner WA, Schofield PR, Schork N, Schulze TG, Schumacher J, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Smith EN, Squassina A, Stamm T, Stopkova P, Streit F, Strohmaier J, Szelinger S, Tighe SK, Tortorella A, Turecki G, Vieta E, Volkert J, Witt SH, Wright A, Zandi PP, Zhang P, Zollner S, McMahon FJ. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet. 2016 Aug 01; 25(15):3383-3394. PMID: 27329760.
      View in: PubMed
    31. Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork N, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ, Dale AM, Jernigan TL, Gruen JR. Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Brain Imaging Behav. 2016 Mar; 10(1):272-82. PMID: 25953057; PMCID: PMC4639472.
    32. Bhutani K, Nazor KL, Williams R, Tran H, Dai H, Džakula Ž, Cho EH, Pang AW, Rao M, Cao H, Schork N, Loring JF. Whole-genome mutational burden analysis of three pluripotency induction methods. Nat Commun. 2016 Feb 19; 7:10536. PMID: 26892726; PMCID: PMC4762882.
    33. Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nat Protoc. 2016 Mar; 11(3):499-524. PMID: 26890679; PMCID: PMC4941947.
    34. Magnuson V, Wang Y, Schork N. Normalizing sleep quality disturbed by psychiatric polypharmacy and sleep apnea: a comprehensive patient-centered N-of-1 study. F1000Res. 2016; 5:132. PMID: 28781744.
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    35. Buscot MJ, Magnussen CG, Juonala M, Pitkänen N, Lehtimäki T, Viikari JS, Kähönen M, Hutri-Kähönen N, Schork N, Raitakari OT, Thomson RJ. The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study. PLoS One. 2016; 11(1):e0146081. PMID: 26731281; PMCID: PMC4701181.
    36. Libiger O, Schork N. Partial Least Squares Regression Can Aid in Detecting Differential Abundance of Multiple Features in Sets of Metagenomic Samples. Front Genet. 2015; 6:350. PMID: 26734061; PMCID: PMC4681790.
    37. Norden-Krichmar TM, Gizer IR, Phillips E, Wilhelmsen KC, Schork N, Ehlers CL. Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort. Twin Res Hum Genet. 2015 Dec; 18(6):727-37. PMID: 26608796; PMCID: PMC4727900 [Available on 12/01/16].
    38. Coombes B, Basu S, Guha S, Schork N. Weighted Score Tests Implementing Model-Averaging Schemes in Detection of Rare Variants in Case-Control Studies. PLoS One. 2015; 10(10):e0139355. PMID: 26436424; PMCID: PMC4593572.
    39. Standish KA, Carland TM, Lockwood GK, Pfeiffer W, Tatineni M, Huang CC, Lamberth S, Cherkas Y, Brodmerkel C, Jaeger E, Smith L, Rajagopal G, Curran ME, Schork N. Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies. BMC Bioinformatics. 2015 Sep 22; 16:304. PMID: 26395405; PMCID: PMC4580299.
    40. Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork N, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham MC, Browner WS, Cummings SR. Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1418-24. PMID: 26328603; PMCID: PMC4612388 [Available on 11/01/16].
    41. Loomba R, Schork N, Chen CH, Bettencourt R, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Seki E, Nelson KE, Sirlin CB, Brenner D. Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. 2015 Dec; 149(7):1784-93. PMID: 26299412; PMCID: PMC4663110 [Available on 12/01/16].
    42. Chen CH, Peng Q, Schork N, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ. Large-scale genomics unveil polygenic architecture of human cortical surface area. Nat Commun. 2015 Jul 20; 6:7549. PMID: 26189703; PMCID: PMC4518289.
    43. Newman E, Thompson WK, Bartsch H, Hagler DJ, Chen CH, Brown TT, Kuperman JM, McCabe C, Chung Y, Libiger O, Akshoomoff N, Bloss CS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Murray SS, Sowell ER, Schork N, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM, Jernigan TL. Anxiety is related to indices of cortical maturation in typically developing children and adolescents. Brain Struct Funct. 2016 07; 221(6):3013-25. PMID: 26183468.
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    44. Fan CC, Bartsch H, Schork AJ, Chen CH, Wang Y, Lo MT, Brown TT, Kuperman JM, Hagler DJ, Schork N, Jernigan TL, Dale AM. Modeling the 3D geometry of the cortical surface with genetic ancestry. Curr Biol. 2015 Aug 03; 25(15):1988-92. PMID: 26166778; PMCID: PMC4786069.
    45. Yin X, Cheng H, Lin Y, Wineinger NE, Zhou F, Sheng Y, Yang C, Li P, Li F, Shen C, Yang S, Schork N, Zhang X. A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese. PLoS One. 2015; 10(5):e0125369. PMID: 25933357; PMCID: PMC4416725.
    46. Jernigan TL, Brown TT, Hagler DJ, Akshoomoff N, Bartsch H, Newman E, Thompson WK, Bloss CS, Murray SS, Schork N, Kennedy DN, Kuperman JM, McCabe C, Chung Y, Libiger O, Maddox M, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Sowell ER, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM. The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository. Neuroimage. 2016 Jan 01; 124(Pt B):1149-54. PMID: 25937488; PMCID: PMC4628902 [Available on 01/01/17].
    47. Schork N. Personalized medicine: Time for one-person trials. Nature. 2015 Apr 30; 520(7549):609-11. PMID: 25925459.
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    48. Noble KG, Houston SM, Brito NH, Bartsch H, Kan E, Kuperman JM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork N, Murray SS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Van Zijl P, Mostofsky S, Kaufmann WE, Kenet T, Dale AM, Jernigan TL, Sowell ER. Family income, parental education and brain structure in children and adolescents. Nat Neurosci. 2015 May; 18(5):773-8. PMID: 25821911; PMCID: PMC4414816.
    49. Bloss CS, Zeeland AA, Topol SE, Darst BF, Boeldt DL, Erikson GA, Bethel KJ, Bjork RL, Friedman JR, Hwynn N, Patay BA, Pockros PJ, Scott ER, Simon RA, Williams GW, Schork N, Topol EJ, Torkamani A. A genome sequencing program for novel undiagnosed diseases. Genet Med. 2015 Dec; 17(12):995-1001. PMID: 25790160; PMCID: PMC4575596.
    50. Pham PH, Shipman WJ, Erikson GA, Schork N, Torkamani A. Scripps Genome ADVISER: Annotation and Distributed Variant Interpretation SERver. PLoS One. 2015; 10(2):e0116815. PMID: 25706643; PMCID: PMC4338027.
    51. Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI, Edenberg HJ, Gershon ES, Schork N. Rare variants in neuronal excitability genes influence risk for bipolar disorder. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3576-81. PMID: 25730879; PMCID: PMC4371952.
    52. Mangino M, Christiansen L, Stone R, Hunt SC, Horvath K, Eisenberg DT, Kimura M, Petersen I, Kark JD, Herbig U, Reiner AP, Benetos A, Codd V, Nyholt DR, Sinnreich R, Christensen K, Nassar H, Hwang SJ, Levy D, Bataille V, Fitzpatrick AL, Chen W, Berenson GS, Samani NJ, Martin NG, Tishkoff S, Schork N, Kyvik KO, Dalgård C, Spector TD, Aviv A. DCAF4, a novel gene associated with leucocyte telomere length. J Med Genet. 2015 Mar; 52(3):157-62. PMID: 25624462; PMCID: PMC4345921.
    53. Zhi X, Lamperska K, Golusinski P, Schork N, Luczewski L, Kolenda T, Golusinski W, Masternak MM. Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence. Oncotarget. 2015 Jan 01; 6(1):547-55. PMID: 25575813; PMCID: PMC4381614.
    54. Norden-Krichmar TM, Gizer IR, Wilhelmsen KC, Schork N, Ehlers CL. Protective variant associated with alcohol dependence in a Mexican American cohort. BMC Med Genet. 2014 Dec 21; 15:136. PMID: 25527893; PMCID: PMC4337107.
    55. Zhang K, Mir SA, Hightower CM, Miramontes-Gonzalez JP, Maihofer AX, Chen Y, Mahata SK, Nievergelt CM, Schork N, Freedman BI, Vaingankar SM, O'Connor DT. Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107. J Am Soc Nephrol. 2015 Aug; 26(8):1816-25. PMID: 25392232; PMCID: PMC4520173.
    56. Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork N, Miller MW, Logue MW, Geyer MA, Risbrough VB, O'Connor DT, Baker DG. Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology. 2015 Jan; 51:459-71. PMID: 25456346.
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    57. Peng Q, Gizer IR, Libiger O, Bizon C, Wilhelmsen KC, Schork N, Ehlers CL. Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample. Am J Med Genet B Neuropsychiatr Genet. 2014 Dec; 165B(8):673-83. PMID: 25270064; PMCID: PMC4364382.
    58. Peterson SN, Meissner T, Su AI, Snesrud E, Ong AC, Schork N, Bretz WA. Functional expression of dental plaque microbiota. Front Cell Infect Microbiol. 2014; 4:108. PMID: 25177549; PMCID: PMC4132376.
    59. Clarke TK, Crist RC, Doyle GA, Weiss AR, Brandt H, Crawford S, Crow S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB, Keel P, Klump KL, Lilenfeld L, Plotnicov K, Magistretti PJ, Bergen AW, Kaye WH, Schork N, Berrettini WH. Characterization of genetic variation in the VGLL4 gene in anorexia nervosa. Psychiatr Genet. 2014 Aug; 24(4):183-4. PMID: 24983835; PMCID: PMC4104366.
    60. Goetz LH, Uribe-Bruce L, Quarless D, Libiger O, Schork N. Admixture and clinical phenotypic variation. Hum Hered. 2014; 77(1-4):73-86. PMID: 25060271.
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    61. Bright AT, Manary MJ, Tewhey R, Arango EM, Wang T, Schork N, Yanow SK, Winzeler EA. A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings. PLoS Negl Trop Dis. 2014 Jun; 8(6):e2882. PMID: 24901334.
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    62. Tewhey R, Gu B, Kelesidis T, Charlton C, Bobenchik A, Hindler J, Schork N, Humphries RM. Mechanisms of linezolid resistance among coagulase-negative staphylococci determined by whole-genome sequencing. MBio. 2014 May 13; 5(3):e00894-14. PMID: 24915435.
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    63. Zhi X, Lamperska K, Golusinski P, Schork N, Luczewski L, Golusinski W, Masternak MM. Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma. Growth Horm IGF Res. 2014 Aug; 24(4):137-41. PMID: 24802266; PMCID: PMC4083007.
    64. Rana BK, Darst BF, Bloss C, Shih PA, Depp C, Nievergelt CM, Allison M, Parsons JK, Schork N, Jeste DV. Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. Am J Geriatr Psychiatry. 2014 Oct; 22(10):997-1006.e5. PMID: 24791650.
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    65. Chen YZ, Friedman JR, Chen DH, Chan GC, Bloss CS, Hisama FM, Topol SE, Carson AR, Pham PH, Bonkowski ES, Scott ER, Lee JK, Zhang G, Oliveira G, Xu J, Scott-Van Zeeland AA, Chen Q, Levy S, Topol EJ, Storm D, Swanson PD, Bird TD, Schork N, Raskind WH, Torkamani A. Gain-of-function ADCY5 mutations in familial dyskinesia with facial myokymia. Ann Neurol. 2014 Apr; 75(4):542-9. PMID: 24700542; PMCID: PMC4457323.
    66. Nievergelt CM, Wineinger NE, Libiger O, Pham P, Zhang G, Baker DG. Chip-based direct genotyping of coding variants in genome wide association studies: utility, issues and prospects. Gene. 2014 Apr 25; 540(1):104-9. PMID: 24521671; PMCID: PMC3980715.
    67. Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork N, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22; 63(15):1542-55. PMID: 24509276; PMCID: PMC3992204.
    68. Peng Q, Schork N. Utility of network integrity methods in therapeutic target identification. Front Genet. 2014; 5:12. PMID: 24550933; PMCID: PMC3909879.
    69. Yurgil KA, Barkauskas DA, Vasterling JJ, Nievergelt CM, Larson GE, Schork N, Litz BT, Nash WP, Baker DG. Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines. JAMA Psychiatry. 2014 Feb; 71(2):149-57. PMID: 24337530.
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    70. Yin X, Wineinger NE, Cheng H, Cui Y, Zhou F, Zuo X, Zheng X, Yang S, Schork N, Zhang X. Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population. BMC Genomics. 2014 Jan 30; 15:87. PMID: 24479639; PMCID: PMC3909441.
    71. Corby PM, Biesbrock A, Gerlach R, Corby AL, Moreira A, Schork N, Bretz WA. Treatment responses to tooth whitening in twins. Twin Res Hum Genet. 2014 Feb; 17(1):23-6. PMID: 24429255.
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    72. Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, Cooper-Dehoff RM, Gaunt TR, Gieger C, Gong Y, Gorski M, Heard-Costa N, Johnson T, Lamonte MJ, McDonough C, Monda KL, Onland-Moret NC, Nelson CP, O'Connell JR, Ordovas J, Peter I, Peters A, Shaffer J, Shen H, Smith E, Speilotes L, Thomas F, Thorand B, Monique Verschuren WM, Anand SS, Dominiczak A, Davidson KW, Hegele RA, Heid I, Hofker MH, Huggins GS, Illig T, Johnson JA, Kirkland S. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet. 2014 May 01; 23(9):2498-510. PMID: 24345515; PMCID: PMC3988452.
    73. Bloss CS, Schork N, Topol EJ. Direct-to-consumer pharmacogenomic testing is associated with increased physician utilisation. J Med Genet. 2014 Feb; 51(2):83-9. PMID: 24343916.
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    74. Ye X, Linton JM, Schork N, Buck LB, Petrascheck M. A pharmacological network for lifespan extension in Caenorhabditis elegans. Aging Cell. 2014 Apr; 13(2):206-15. PMID: 24134630; PMCID: PMC3955372.
    75. Akshoomoff N, Newman E, Thompson WK, McCabe C, Bloss CS, Chang L, Amaral DG, Casey BJ, Ernst TM, Frazier JA, Gruen JR, Kaufmann WE, Kenet T, Kennedy DN, Libiger O, Mostofsky S, Murray SS, Sowell ER, Schork N, Dale AM, Jernigan TL. The NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING). Neuropsychology. 2014 Jan; 28(1):1-10. PMID: 24219608.
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    76. Tranah GJ, Yokoyama JS, Katzman SM, Nalls MA, Newman AB, Harris TB, Cesari M, Manini TM, Schork N, Cummings SR, Liu Y, Yaffe K. Mitochondrial DNA sequence associations with dementia and amyloid-ß in elderly African Americans. Neurobiol Aging. 2014 Feb; 35(2):442.e1-8. PMID: 24140124.
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    77. Zhang K, Deacon DC, Rao F, Schork AJ, Fung MM, Waalen J, Schork N, Nievergelt CM, Chi NC, O'Connor DT. Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]. J Am Coll Cardiol. 2014 Feb 04; 63(4):358-68. PMID: 24140660; PMCID: PMC3946708.
    78. Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, Do C, Torkamani A, Tycko B. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation. PLoS Genet. 2013 Aug; 9(8):e1003622. PMID: 24009515; PMCID: PMC3757050.
    79. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94. PMID: 23933821.
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    80. Schork N. Genetic parts to a preventive medicine whole. Genome Med. 2013; 5(6):54. PMID: 23806045; PMCID: PMC3706981.
    81. Wineinger NE, Harper A, Libiger O, Srinivasan SR, Chen W, Berenson GS, Schork N. Genomic risk models improve prediction of longitudinal lipid levels in children and young adults. Front Genet. 2013; 4:86. PMID: 23734161; PMCID: PMC3659298.
    82. Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork N, Pravenec M, Mahata SK, Schmid-Schönbein GW, O'Connor DT. MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension. Hum Mol Genet. 2013 Sep 15; 22(18):3624-40. PMID: 23674521; PMCID: PMC3749858.
    83. Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Light GA, Braff DL. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2013 May; 170(5):521-32. PMID: 23511790; PMCID: PMC3878873.
    84. Schork N, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet. 2013 Apr; 9(4):e1003449. PMID: 23637621.
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    85. Demerath EW, Liu CT, Franceschini N, Chen G, Palmer JR, Smith EN, Chen CT, Ambrosone CB, Arnold AM, Bandera EV, Berenson GS, Bernstein L, Britton A, Cappola AR, Carlson CS, Chanock SJ, Chen W, Chen Z, Deming SL, Elks CE, Evans MK, Gajdos Z, Henderson BE, Hu JJ, Ingles S, John EM, Kerr KF, Kolonel LN, Le Marchand L, Lu X, Millikan RC, Musani SK, Nock NL, North K, Nyante S, Press MF, Rodriquez-Gil JL, Ruiz-Narvaez EA, Schork N, Srinivasan SR, Woods NF, Zheng W, Ziegler RG, Zonderman A, Heiss G, Gwen Windham B, Wellons M, Murray SS, Nalls M, Pastinen T, Rajkovic A, Hirschhorn J, Adrienne Cupples L, Kooperberg C, Murabito JM, Haiman CA. Genome-wide association study of age at menarche in African-American women. Hum Mol Genet. 2013 Aug 15; 22(16):3329-46. PMID: 23599027; PMCID: PMC3723312.
    86. Bloss CS, Wineinger NE, Darst BF, Schork N, Topol EJ. Impact of direct-to-consumer genomic testing at long term follow-up. J Med Genet. 2013 Jun; 50(6):393-400. PMID: 23559530.
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    87. Petersen DC, Libiger O, Tindall EA, Hardie RA, Hannick LI, Glashoff RH, Mukerji M. Complex patterns of genomic admixture within southern Africa. PLoS Genet. 2013; 9(3):e1003309. PMID: 23516368; PMCID: PMC3597481.
    88. Peterson SN, Snesrud E, Liu J, Ong AC, Kilian M, Schork N, Bretz W. The dental plaque microbiome in health and disease. PLoS One. 2013; 8(3):e58487. PMID: 23520516.
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    89. Schmitz RJ, Schultz MD, Urich MA, Nery JR, Pelizzola M, Libiger O, Alix A, McCosh RB, Chen H, Schork N, Ecker JR. Patterns of population epigenomic diversity. Nature. 2013 Mar 14; 495(7440):193-8. PMID: 23467092; PMCID: PMC3798000.
    90. Darst BF, Madlensky L, Schork N, Topol EJ, Bloss CS. Characteristics of genomic test consumers who spontaneously share results with their health care provider. Health Commun. 2014; 29(1):105-8. PMID: 23384116; PMCID: PMC3679226.
    91. Libiger O, Schork N. A Method for Inferring an Individual's Genetic Ancestry and Degree of Admixture Associated with Six Major Continental Populations. Front Genet. 2012; 3:322. PMID: 23335941; PMCID: PMC3543981.
    92. Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten J, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Apr 15; 22(8):1663-78. PMID: 23303523.
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    93. Miller MB, Basu S, Cunningham J, Eskin E, Malone SM, Oetting WS, Schork N, Sul JH, Iacono WG, McGue M. The Minnesota Center for Twin and Family Research genome-wide association study. Twin Res Hum Genet. 2012 Dec; 15(6):767-74. PMID: 23363460; PMCID: PMC3561927.
    94. Smith JG, Avery CL, Evans DS, Nalls MA, Meng YA, Smith EN, Palmer C, Tanaka T, Mehra R, Butler AM, Young T, Buxbaum SG, Kerr KF, Berenson GS, Schnabel RB, Li G, Ellinor PT, Magnani JW, Chen W, Bis JC, Curb JD, Hsueh WC, Rotter JI, Liu Y, Newman AB, Limacher MC, North KE, Reiner AP, Quibrera PM, Schork N, Singleton AB, Psaty BM, Soliman EZ, Solomon AJ, Srinivasan SR, Alonso A, Wallace R, Redline S, Zhang ZM, Post WS, Zonderman AB, Taylor HA, Murray SS, Ferrucci L, Arking DE, Evans MK, Fox ER, Sotoodehnia N, Heckbert SR, Whitsel EA, Newton-Cheh C. Impact of ancestry and common genetic variants on QT interval in African Americans. Circ Cardiovasc Genet. 2012 Dec; 5(6):647-55. PMID: 23166209.
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    95. Walhovd KB, Fjell AM, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork N, Darst BF, Casey BJ, Chang L, Ernst TM, Frazier J, Gruen JR, Kaufmann WE, Murray SS, van Zijl P, Mostofsky S, Dale AM. Long-term influence of normal variation in neonatal characteristics on human brain development. Proc Natl Acad Sci U S A. 2012 Dec 04; 109(49):20089-94. PMID: 23169628; PMCID: PMC3523836.
    96. Bailer UF, Frank GK, Price JC, Meltzer CC, Becker C, Mathis CA, Wagner A, Barbarich-Marsteller NC, Bloss CS, Putnam K, Schork N, Gamst A, Kaye WH. Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa. Psychiatry Res. 2013 Feb 28; 211(2):160-8. PMID: 23154100; PMCID: PMC3880148.
    97. Fjell AM, Walhovd KB, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Venkatraman V, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Darst BF, Schork N, Casey BJ, Chang L, Ernst TM, Gruen JR, Kaufmann WE, Kenet T, Frazier J, Murray SS, Sowell ER, van Zijl P, Mostofsky S, Jernigan TL, Dale AM. Multimodal imaging of the self-regulating developing brain. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19620-5. PMID: 23150548; PMCID: PMC3511748.
    98. Butler AM, Yin X, Evans DS, Nalls MA, Smith EN, Tanaka T, Li G, Buxbaum SG, Whitsel EA, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen W, Deo R, Ellinor PT, Heckbert SR, Heiss G, Hsueh WC, Keating BJ, Kerr KF, Li Y, Limacher MC, Liu Y, Lubitz SA, Marciante KD, Mehra R, Meng YA, Newman AB, Newton-Cheh C, North KE, Palmer CD, Psaty BM, Quibrera PM, Redline S, Reiner AP, Rotter JI, Schnabel RB, Schork N, Singleton AB, Smith JG, Soliman EZ, Srinivasan SR, Zhang ZM, Zonderman AB, Ferrucci L, Murray SS, Evans MK, Sotoodehnia N, Magnani JW, Avery CL. Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circ Cardiovasc Genet. 2012 Dec; 5(6):639-46. PMID: 23139255.
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    99. Torkamani A, Pham P, Libiger O, Bansal V, Zhang G, Scott-Van Zeeland AA, Tewhey R, Topol EJ, Schork N. Clinical implications of human population differences in genome-wide rates of functional genotypes. Front Genet. 2012; 3:211. PMID: 23125845; PMCID: PMC3485509.
    100. Vassy JL, Dasmahapatra P, Meigs JB, Schork N, Magnussen CG, Chen W, Raitakari OT, Pencina MJ, Jamal SM, Berenson GS, Goodman E. Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population. Pediatrics. 2012 Nov; 130(5):e1235-42. PMID: 23071215; PMCID: PMC3483893.
    101. Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, Gong Y, Hopewell JC, Johnson T, Kleber ME, Langaee TY, Li M, Li YR, Liu K, McDonough CW, Meijs MF, Middelberg RP, Musunuru K, Nelson CP, O'Connell JR, Padmanabhan S, Pankow JS, Pankratz N, Rafelt S, Rajagopalan R, Romaine SP, Schork N, Shaffer J, Shen H, Smith EN, Tischfield SE, van der Most PJ, van Vliet-Ostaptchouk JV, Verweij N, Volcik KA, Zhang L, Bailey KR, Bailey KM, Bauer F, Boer JM, Braund PS, Burt A, Burton PR, Buxbaum SG, Chen W, Cooper-Dehoff RM, Cupples LA, deJong JS, Delles C, Duggan D, Fornage M, Furlong CE, Glazer N, Gums JG, Hastie C, Holmes MV, Illig T, Kirkland SA, Kivimaki M, Klein R, Klein BE, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix AZ, Mallela L, Murugesan G, Ordovas J, Ouwehand WH, Post WS, Saxena R, Scharnagl H, Schreiner PJ, Shah T, Shields DC, Shimbo D, Srinivasan SR, Stolk RP, Swerdlow DI, Taylor HA, Topol EJ, Toskala E, van Pelt JL, van Setten J, Yusuf S, Whittaker JC, Zwinderman AH. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. 2012 Nov 02; 91(5):823-38. PMID: 23063622.
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    102. Nissen S, Liang S, Shehktman T, Kelsoe JR. Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec; 159B(8):941-50. PMID: 23038240.
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    103. Verma-Gaur J, Torkamani A, Schaffer L, Head SR, Schork N, Feeney AJ. Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):17004-9. PMID: 23027941; PMCID: PMC3479473.
    104. Zapala MA, Schork N. Statistical properties of multivariate distance matrix regression for high-dimensional data analysis. Front Genet. 2012; 3:190. PMID: 23060897; PMCID: PMC3461701.
    105. Zhang K, Rao F, Miramontes-Gonzalez JP, Hightower CM, Vaught B, Chen Y, Greenwood TA, Schork AJ, Wang L, Mahata M, Stridsberg M, Khandrika S, Biswas N, Fung MM, Waalen J, Middelberg RP, Heath AC, Montgomery GW, Martin NG, Whitfield JB, Baker DG, Schork N, Nievergelt CM, O'Connor DT. Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses. J Am Coll Cardiol. 2012 Oct 23; 60(17):1678-89. PMID: 23021333; PMCID: PMC3687554.
    106. Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen TW, Müller-Myhsok B, Steffens M, Schmael C, McMahon FJ. Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1. Transl Psychiatry. 2012 Sep 25; 2:e165. PMID: 23010768; PMCID: PMC3565205.
    107. Tewhey R, Cannavino CR, Leake JA, Bansal V, Topol EJ, Torkamani A, Bradley JS, Schork N. Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300. BMC Genomics. 2012 Sep 25; 13:508. PMID: 23009684; PMCID: PMC3598774.
    108. Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, Fitzpatrick AL, Christiansen L, Petersen I, Elbers CC, Harris T, Chen W, Srinivasan SR, Kark JD, Benetos A, El Shamieh S, Visvikis-Siest S, Christensen K, Berenson GS, Valdes AM, Viñuela A, Garcia M, Arnett DK, Broeckel U, Province MA, Pankow JS, Kammerer C, Liu Y, Nalls M, Tishkoff S, Thomas F, Ziv E, Psaty BM, Bis JC, Rotter JI, Taylor KD, Smith E, Schork N, Levy D, Aviv A. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet. 2012 Dec 15; 21(24):5385-94. PMID: 23001564; PMCID: PMC3510758.
    109. Humphries RM, Kelesidis T, Tewhey R, Rose WE, Schork N, Nizet V, Sakoulas G. Genotypic and phenotypic evaluation of the evolution of high-level daptomycin nonsusceptibility in vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012 Nov; 56(11):6051-3. PMID: 22948885; PMCID: PMC3486580.
    110. Pallmann P, Schaarschmidt F, Hothorn LA, Fischer C, Nacke H, Priesnitz KU, Schork N. Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices. Mol Ecol Resour. 2012 Nov; 12(6):1068-78. PMID: 22934781; PMCID: PMC3470749.
    111. Glatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne E. Blood-based gene expression signatures of infants and toddlers with autism. J Am Acad Child Adolesc Psychiatry. 2012 Sep; 51(9):934-44.e2. PMID: 22917206.
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    112. Mei H, Chen W, Mills K, He J, Srinivasan SR, Schork N, Murray S, Berenson GS. Influences of FTO gene on onset age of adult overweight. Hum Genet. 2012 Dec; 131(12):1851-9. PMID: 22842737.
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    113. Price MJ, Murray SS, Angiolillo DJ, Lillie E, Smith EN, Tisch RL, Schork N, Teirstein PS, Topol EJ. Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: the GIFT (Genotype Information and Functional Testing) study. J Am Coll Cardiol. 2012 May 29; 59(22):1928-37. PMID: 22624833.
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    114. Baker DG, Nash WP, Litz BT, Geyer MA, Risbrough VB, Nievergelt CM, O'Connor DT, Larson GE, Schork N, Vasterling JJ, Hammer PS, Webb-Murphy JA. Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study. Prev Chronic Dis. 2012; 9:E97. PMID: 22575082; PMCID: PMC3431952.
    115. Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork N, Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet. 2012; 8(3):e1002592. PMID: 22457638.
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    116. Damani S, Bacconi A, Libiger O, Chourasia AH, Serry R, Gollapudi R, Goldberg R, Rapeport K, Haaser S, Topol S, Knowlton S, Bethel K, Kuhn P, Wood M, Carragher B, Schork N, Jiang J, Rao C, Connelly M, Fowler VM, Topol EJ. Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med. 2012 Mar 21; 4(126):126ra33. PMID: 22440735; PMCID: PMC3589570.
    117. Dwyer T, Sun C, Magnussen CG, Raitakari OT, Schork N, Venn A, Burns TL, Juonala M, Steinberger J, Sinaiko AR, Prineas RJ, Davis PH, Woo JG, Morrison JA, Daniels SR, Chen W, Srinivasan SR, Viikari JS, Berenson GS. Cohort Profile: the international childhood cardiovascular cohort (i3C) consortium. Int J Epidemiol. 2013 Feb; 42(1):86-96. PMID: 22434861; PMCID: PMC3600617.
    118. Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork N. Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Front Genet. 2012; 3:11. PMID: 22375143.
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    119. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork N, Dale AM. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. PMID: 22343285.
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    120. Mei H, Chen W, Jiang F, He J, Srinivasan S, Smith EN, Schork N, Murray S, Berenson GS. Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood. PLoS One. 2012; 7(2):e31470. PMID: 22355368; PMCID: PMC3280302.
    121. Aoki-Ota M, Torkamani A, Ota T, Schork N, Nemazee D. Skewed primary Ig? repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. J Immunol. 2012 Mar 01; 188(5):2305-15. PMID: 22287713; PMCID: PMC3288532.
    122. Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork N, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies. PLoS One. 2012; 7(1):e28931. PMID: 22295058; PMCID: PMC3266236.
    123. Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork N, Steinberg MH, Perls TT. Whole genome sequences of a male and female supercentenarian, ages greater than 114?years. Front Genet. 2011; 2:90. PMID: 22303384; PMCID: PMC3262222.
    124. Miller VM, Kaplan JR, Schork N, Ouyang P, Berga SL, Wenger NK, Shaw LJ, Webb RC, Mallampalli M, Steiner M, Taylor DA, Merz CN, Reckelhoff JF. Strategies and methods to study sex differences in cardiovascular structure and function: a guide for basic scientists. Biol Sex Differ. 2011 Dec 12; 2:14. PMID: 22152231; PMCID: PMC3292512.
    125. Vrieze SI, McGue M, Miller MB, Legrand LN, Schork N, Iacono WG. An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design. PLoS Genet. 2011 Dec; 7(12):e1002413. PMID: 22174699.
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    126. Bretz WA, Biesbrock A, Corby PM, Corby AL, Bretz WG, Wessel J, Schork N. Environmental and genetic contributions to indicators of oral malodor in twins. Twin Res Hum Genet. 2011 Dec; 14(6):568-72. PMID: 22506313; PMCID: PMC3335767.
    127. Bloss CS, Topol EJ, Schork N. Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease. Genet Epidemiol. 2012 Jan; 36(1):66-70. PMID: 22127769; PMCID: PMC3338895.
    128. Bloss CS, Madlensky L, Schork N, Topol EJ. Genomic information as a behavioral health intervention: can it work? Per Med. 2011 Nov; 8(6):659-667. PMID: 22199991.
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    129. Oikonen M, Tikkanen E, Juhola J, Tuovinen T, Seppälä I, Juonala M, Taittonen L, Mikkilä V, Kähönen M, Ripatti S, Viikari J, Lehtimäki T, Havulinna AS, Kee F, Newton-Cheh C, Peltonen L, Schork N, Murray SS, Berenson GS, Chen W, Srinivasan SR, Salomaa V, Raitakari OT. Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study. Hypertension. 2011 Dec; 58(6):1079-85. PMID: 22025373; PMCID: PMC3247907.
    130. Schmitz RJ, Schultz MD, Lewsey MG, O'Malley RC, Urich MA, Libiger O, Schork N, Ecker JR. Transgenerational epigenetic instability is a source of novel methylation variants. Science. 2011 Oct 21; 334(6054):369-73. PMID: 21921155; PMCID: PMC3210014.
    131. Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork N. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. BMC Genomics. 2011 Sep 10; 12:449. PMID: 21906392.
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    132. Bakken TE, Dale AM, Schork N. A geographic cline of skull and brain morphology among individuals of European Ancestry. Hum Hered. 2011; 72(1):35-44. PMID: 21849792; PMCID: PMC3171282.
    133. Winn ME, Shaw M, April C, Klotzle B, Fan JB, Murray SS, Schork N. Gene expression profiling of human whole blood samples with the Illumina WG-DASL assay. BMC Genomics. 2011 Aug 15; 12:412. PMID: 21843359; PMCID: PMC3175478.
    134. Bloss CS, Darst BF, Topol EJ, Schork N. Direct-to-consumer personalized genomic testing. Hum Mol Genet. 2011 Oct 15; 20(R2):R132-41. PMID: 21828075; PMCID: PMC3179383.
    135. Torkamani A, Scott-Van Zeeland AA, Topol EJ, Schork N. Annotating individual human genomes. Genomics. 2011 Oct; 98(4):233-41. PMID: 21839162; PMCID: PMC4074010.
    136. Bakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork N. Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia. Arch Gen Psychiatry. 2011 Aug; 68(8):781-90. PMID: 21810643; PMCID: PMC3375053.
    137. Peterson SN, Snesrud E, Schork N, Bretz WA. Dental caries pathogenicity: a genomic and metagenomic perspective. Int Dent J. 2011 Aug; 61 Suppl 1:11-22. PMID: 21726221; PMCID: PMC3699854.
    138. Root TL, Szatkiewicz JP, Jonassaint CR, Thornton LM, Pinheiro AP, Strober M, Bloss C, Berrettini W, Schork N, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Rotondo A, Treasure J, Woodside DB, Bulik CM. Association of candidate genes with phenotypic traits relevant to anorexia nervosa. Eur Eat Disord Rev. 2011 Nov-Dec; 19(6):487-93. PMID: 21780254.
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    139. Bloss CS, Berrettini W, Bergen AW, Magistretti P, Duvvuri V, Strober M, Brandt H, Crawford S, Crow S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, Keel P, Klump KL, Mitchell J, Treasure J, Woodside DB, Marzola E, Schork N, Kaye WH. Genetic association of recovery from eating disorders: the role of GABA receptor SNPs. Neuropsychopharmacology. 2011 Oct; 36(11):2222-32. PMID: 21750581; PMCID: PMC3176559.
    140. Smith EN, Koller DL, Panganiban C, Szelinger S, Zhang P, Badner JA, Barrett TB, Berrettini WH, Bloss CS, Byerley W, Coryell W, Edenberg HJ, Foroud T, Gershon ES, Greenwood TA, Guo Y, Hipolito M, Keating BJ, Lawson WB, Liu C, Mahon PB, McInnis MG, McMahon FJ, McKinney R, Murray SS, Nievergelt CM, Nurnberger JI, Nwulia EA, Potash JB, Rice J, Schulze TG, Scheftner WA, Shilling PD, Zandi PP, Zöllner S, Craig DW, Schork N, Kelsoe JR. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. PLoS Genet. 2011 Jun; 7(6):e1002134. PMID: 21738484; PMCID: PMC3128104.
    141. Luo W, Schork N, Marschke KB, Ng SC, Hermann TW, Zhang J, Sanders JM, Tooker P, Malo N, Zapala MA, Dziewanowska ZE, Negro-Vilar A, Meglasson MD. Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer. Anticancer Res. 2011 Jun; 31(6):2303-11. PMID: 21737656.
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    142. Fung MM, Salem RM, Lipkowitz MS, Bhatnagar V, Pandey B, Schork N, O'Connor DT. Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC). Nephrol Dial Transplant. 2012 Jan; 27(1):197-205. PMID: 21613384; PMCID: PMC3350339.
    143. Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork N, Schlissel MS, Riblet R, Murre C, Feeney AJ. CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci U S A. 2011 Jun 07; 108(23):9566-71. PMID: 21606361; PMCID: PMC3111298.
    144. Greenwood TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, Radant AD, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Freedman R, Braff DL. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2011 Sep; 168(9):930-46. PMID: 21498463; PMCID: PMC3751972.
    145. Bansal V, Tewhey R, Leproust EM, Schork N. Efficient and cost effective population resequencing by pooling and in-solution hybridization. PLoS One. 2011 Mar 30; 6(3):e18353. PMID: 21479135; PMCID: PMC3068187.
    146. Cheng J, Torkamani A, Grover RK, Jones TM, Ruiz DI, Schork N, Quigley MM, Hall FW, Salomon DR, Lerner RA. Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal. Proc Natl Acad Sci U S A. 2011 Apr 05; 108(14):5560-5. PMID: 21415369; PMCID: PMC3078383.
    147. Price MJ, Berger PB, Teirstein PS, Tanguay JF, Angiolillo DJ, Spriggs D, Puri S, Robbins M, Garratt KN, Bertrand OF, Stillabower ME, Stillablower ME, Aragon JR, Kandzari DE, Stinis CT, Lee MS, Manoukian SV, Cannon CP, Schork N, Topol EJ. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. JAMA. 2011 Mar 16; 305(11):1097-105. PMID: 21406646.
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    148. Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork N, Wynshaw-Boris A. Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. PLoS Genet. 2011 Mar; 7(3):e1001331. PMID: 21423666; PMCID: PMC3053345.
    149. Lillie EO, Patay B, Diamant J, Issell B, Topol EJ, Schork N. The n-of-1 clinical trial: the ultimate strategy for individualizing medicine? Per Med. 2011 Mar; 8(2):161-173. PMID: 21695041.
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    150. Tiwari HK, Schork N. Grand challenges in statistical genetics/genomics methodology. Front Genet. 2011; 2:5. PMID: 22303304; PMCID: PMC3268565.
    151. Tewhey R, Bansal V, Torkamani A, Topol EJ, Schork N. The importance of phase information for human genomics. Nat Rev Genet. 2011 03; 12(3):215-23. PMID: 21301473.
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    152. Topol EJ, Schork N, Smith JM. Digital medicine and the Scripps Translational Science Institute. Clin Transl Sci. 2011 Feb; 4(1):8-9. PMID: 21348949.
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    153. Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Roe AH, Schork N, Siever LJ, Silverman JM, Swerdlow NR, Thomas AR, Tsuang DW, Turetsky BI, Seidman LJ. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res. 2011 May; 128(1-3):102-10. PMID: 21288694.
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    154. Bloss CS, Schork N, Topol EJ. Effect of direct-to-consumer genomewide profiling to assess disease risk. N Engl J Med. 2011 Feb 10; 364(6):524-34. PMID: 21226570; PMCID: PMC3786730.
    155. Bansal V, Libiger O, Torkamani A, Schork N. An application and empirical comparison of statistical analysis methods for associating rare variants to a complex phenotype. Pac Symp Biocomput. 2011; 76-87. PMID: 21121035; PMCID: PMC5017238.
    156. Bansal V, Tewhey R, Topol EJ, Schork N. The next phase in human genetics. Nat Biotechnol. 2011 Jan; 29(1):38-9. PMID: 21221098.
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    157. Topol EJ, Schork N. Catapulting clopidogrel pharmacogenomics forward. Nat Med. 2011 Jan; 17(1):40-1. PMID: 21217678.
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    158. Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer Ad, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszewski M, Tomaszweski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork N, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet. 2011 Jan 07; 88(1):6-18. PMID: 21194676; PMCID: PMC3014369.
    159. Bloss CS, Jeste DV, Schork N. Genomics for disease treatment and prevention. Psychiatr Clin North Am. 2011 Mar; 34(1):147-66. PMID: 21333845; PMCID: PMC3073546.
    160. Salem RM, Pandey B, Richard E, Fung MM, Garcia EP, Brophy VH, Schork N, O'Connor DT, Bhatnagar V. The VA Hypertension Primary Care Longitudinal Cohort: Electronic medical records in the post-genomic era. Health Informatics J. 2010 Dec; 16(4):274-86. PMID: 21216807; PMCID: PMC3099595.
    161. Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, d'Adamo P, de Faire U, de Geus EJ, Deloukas P, Döring A, Smith GD, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, Gasparini P, Geller F, Gieger C. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010 Dec; 42(12):1077-85. PMID: 21102462.
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    162. Kerkel K, Schupf N, Hatta K, Pang D, Salas M, Kratz A, Minden M, Murty V, Zigman WB, Mayeux RP, Jenkins EC, Torkamani A, Schork N, Silverman W, Croy BA, Tycko B. Altered DNA methylation in leukocytes with trisomy 21. PLoS Genet. 2010 Nov 18; 6(11):e1001212. PMID: 21124956; PMCID: PMC2987931.
    163. McLachlan S, Lee SM, Steele TM, Hawthorne PL, Zapala MA, Eskin E, Schork N, Anderson GJ, Vulpe CD. In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiol Genomics. 2011 Feb 11; 43(3):136-47. PMID: 21062905; PMCID: PMC3055709.
    164. Bhatia G, Bansal V, Harismendy O, Schork N, Topol EJ, Frazer K, Bafna V. A covering method for detecting genetic associations between rare variants and common phenotypes. PLoS Comput Biol. 2010 Oct 14; 6(10):e1000954. PMID: 20976246.
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    165. Bansal V, Libiger O, Torkamani A, Schork N. Statistical analysis strategies for association studies involving rare variants. Nat Rev Genet. 2010 Nov; 11(11):773-85. PMID: 20940738.
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    166. Rosenberg S, Elashoff MR, Beineke P, Daniels SE, Wingrove JA, Tingley WG, Sager PT, Sehnert AJ, Yau M, Kraus WE, Newby LK, Schwartz RS, Voros S, Ellis SG, Tahirkheli N, Waksman R, McPherson J, Lansky A, Winn ME, Schork N, Topol EJ. Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med. 2010 Oct 05; 153(7):425-34. PMID: 20921541; PMCID: PMC3786733.
    167. Bailer UF, Bloss CS, Frank GK, Price JC, Meltzer CC, Mathis CA, Geyer MA, Wagner A, Becker CR, Schork N, Kaye WH. 5-HT1A receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups. Int J Eat Disord. 2011 Sep; 44(6):477-87. PMID: 20872754; PMCID: PMC4286242.
    168. Smith EN, Chen W, Kähönen M, Kettunen J, Lehtimäki T, Peltonen L, Raitakari OT, Salem RM, Schork N, Shaw M, Srinivasan SR, Topol EJ, Viikari JS, Berenson GS, Murray SS. Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. PLoS Genet. 2010 Sep 09; 6(9):e1001094. PMID: 20838585; PMCID: PMC2936521.
    169. Mei H, Chen W, Srinivasan SR, Jiang F, Schork N, Murray S, Smith E, So JD, Berenson GS. FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI. Hum Genet. 2010 Dec; 128(6):589-96. PMID: 20811910.
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    170. Bloss CS, Ornowski L, Silver E, Cargill M, Vanier V, Schork N, Topol EJ. Consumer perceptions of direct-to-consumer personalized genomic risk assessments. Genet Med. 2010 Sep; 12(9):556-66. PMID: 20717041.
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    171. Bloss CS, Pawlikowska L, Schork N. Contemporary human genetic strategies in aging research. Ageing Res Rev. 2011 Apr; 10(2):191-200. PMID: 20709627.
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    172. Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork N, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB. Association study of 182 candidate genes in anorexia nervosa. Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5):1070-80. PMID: 20468064.
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    173. Lakatos A, Derbeneva O, Younes D, Keator D, Bakken T, Lvova M, Brandon M, Guffanti G, Reglodi D, Saykin A, Weiner M, Macciardi F, Schork N, Wallace DC, Potkin SG. Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort. Neurobiol Aging. 2010 Aug; 31(8):1355-63. PMID: 20538375; PMCID: PMC2918801.
    174. Niculescu AB, Schork N, Salomon DR. Mindscape: a convergent perspective on life, mind, consciousness and happiness. J Affect Disord. 2010 Jun; 123(1-3):1-8. PMID: 19595463.
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    175. Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork N, Hicks PJ, Bowden DW, Freedman BI, Brophy VH, O'Connor DT. Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis. Am J Nephrol. 2010; 32(1):23-30. PMID: 20484896; PMCID: PMC2914391.
    176. Winn ME, Zapala MA, Hovatta I, Risbrough VB, Lillie E, Schork N. The effects of globin on microarray-based gene expression analysis of mouse blood. Mamm Genome. 2010 Jun; 21(5-6):268-75. PMID: 20473674; PMCID: PMC2890980.
    177. Bloss CS, Schiabor KM, Schork N. Human behavioral informatics in genetic studies of neuropsychiatric disease: multivariate profile-based analysis. Brain Res Bull. 2010 Sep 30; 83(3-4):177-88. PMID: 20433907.
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    178. Salem RM, O'Connor DT, Schork N. Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures. Physiol Genomics. 2010 Jul 07; 42(2):236-47. PMID: 20423962; PMCID: PMC3032281.
    179. Levy D, Neuhausen SL, Hunt SC, Kimura M, Hwang SJ, Chen W, Bis JC, Fitzpatrick AL, Smith E, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter JI, Herbig U, Psaty BM, Sastrasinh M, Murray SS, Vasan RS, Province MA, Glazer NL, Lu X, Cao X, Kronmal R, Mangino M, Soranzo N, Spector TD, Berenson GS, Aviv A. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9293-8. PMID: 20421499; PMCID: PMC2889047.
    180. Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Wagner BD, Freedman R. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophr Res. 2010 Jun; 119(1-3):175-82. PMID: 20382002; PMCID: PMC3688282.
    181. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, Nuechterlein KH, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 2010 Sep; 47(5):846-56. PMID: 20374545; PMCID: PMC4176871.
    182. Lanktree MB, Hegele RA, Schork N, Spence JD. Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease. Circ Cardiovasc Genet. 2010 Apr; 3(2):215-21. PMID: 20407100.
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    183. Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akshoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E. Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci. 2010 Mar 24; 30(12):4419-27. PMID: 20335478; PMCID: PMC2859218.
    184. Torkamani A, Dean B, Schork N, Thomas EA. Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia. Genome Res. 2010 Apr; 20(4):403-12. PMID: 20197298; PMCID: PMC2847743.
    185. Schork N, Topol EJ. Genotype-based risk and pharmacogenetic sampling in clinical trials. J Biopharm Stat. 2010 Mar; 20(2):315-33. PMID: 20309761.
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    186. Bansal V, Harismendy O, Tewhey R, Murray SS, Schork N, Topol EJ, Frazer KA. Accurate detection and genotyping of SNPs utilizing population sequencing data. Genome Res. 2010 Apr; 20(4):537-45. PMID: 20150320; PMCID: PMC2847757.
    187. Joo EJ, Greenwood TA, Schork N, McKinney RA, Sadovnick AD, Remick RA, Keck PE, McElroy SL, Kelsoe JR. Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 05; 153B(1):260-8. PMID: 19603423.
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    188. Chen Y, Wen G, Rao F, Zhang K, Wang L, Rodriguez-Flores JL, Sanchez AP, Mahata M, Taupenot L, Sun P, Mahata SK, Tayo B, Schork N, Ziegler MG, Hamilton BA, O'Connor DT. Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. J Hypertens. 2010 Jan; 28(1):76-86. PMID: 20009769; PMCID: PMC2860271.
    189. Lahiry P, Torkamani A, Schork N, Hegele RA. Kinase mutations in human disease: interpreting genotype-phenotype relationships. Nat Rev Genet. 2010 Jan; 11(1):60-74. PMID: 20019687.
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    190. Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork N, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA. Sex-dependent association of common variants of microcephaly genes with brain structure. Proc Natl Acad Sci U S A. 2010 Jan 05; 107(1):384-8. PMID: 20080800; PMCID: PMC2806758.
    191. Schork N, Bansal V. Not so lost in the genetic crowd. Nat Genet. 2009 Nov; 41(11):1163-4. PMID: 19862007.
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    192. Dixit A, Yi L, Gowthaman R, Torkamani A, Schork N, Verkhivker GM. Sequence and structure signatures of cancer mutation hotspots in protein kinases. PLoS One. 2009 Oct 16; 4(10):e7485. PMID: 19834613; PMCID: PMC2759519.
    193. Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork N, Brophy VH, O'Connor DT. Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis. Nephrol Dial Transplant. 2009 Dec; 24(12):3677-86. PMID: 19745105; PMCID: PMC2790952.
    194. Joyner AH, J CR, Bloss CS, Bakken TE, Rimol LM, Melle I, Agartz I, Djurovic S, Topol EJ, Schork N, Andreassen OA, Dale AM. A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations. Proc Natl Acad Sci U S A. 2009 Sep 08; 106(36):15483-8. PMID: 19717458; PMCID: PMC2741277.
    195. Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, Schork N, O'Connor DT, Taylor P. Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs. J Pharmacol Exp Ther. 2009 Nov; 331(2):419-28. PMID: 19671882; PMCID: PMC2775266.
    196. Libiger O, Nievergelt CM, Schork N. Comparison of genetic distance measures using human SNP genotype data. Hum Biol. 2009 Aug; 81(4):389-406. PMID: 20067366.
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    197. Torkamani A, Schork N. Identification of rare cancer driver mutations by network reconstruction. Genome Res. 2009 Sep; 19(9):1570-8. PMID: 19574499; PMCID: PMC2752121.
    198. Torkamani A, Schork N. Prestige centrality-based functional outlier detection in gene expression analysis. Bioinformatics. 2009 Sep 01; 25(17):2222-8. PMID: 19549629.
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    199. Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork N, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, Kwok PY, Ziv E. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell. 2009 Aug; 8(4):460-72. PMID: 19489743; PMCID: PMC3652804.
    200. Schork N, Murray SS, Frazer KA, Topol EJ. Common vs. rare allele hypotheses for complex diseases. Curr Opin Genet Dev. 2009 Jun; 19(3):212-9. PMID: 19481926.
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    201. Frazer KA, Murray SS, Schork N, Topol EJ. Human genetic variation and its contribution to complex traits. Nat Rev Genet. 2009 Apr; 10(4):241-51. PMID: 19293820.
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    202. Harismendy O, Ng PC, Strausberg RL, Wang X, Stockwell TB, Beeson KY, Schork N, Murray SS, Topol EJ, Levy S, Frazer KA. Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biol. 2009; 10(3):R32. PMID: 19327155; PMCID: PMC2691003.
    203. Dixit A, Torkamani A, Schork N, Verkhivker G. Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability. Biophys J. 2009 Feb; 96(3):858-74. PMID: 19186126.
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    204. Zhang K, Rao F, Rana BK, Gayen JR, Calegari F, King A, Rosa P, Huttner WB, Stridsberg M, Mahata M, Vaingankar S, Mahboubi V, Salem RM, Rodriguez-Flores JL, Fung MM, Smith DW, Schork N, Ziegler MG, Taupenot L, Mahata SK, O'Connor DT. Autonomic function in hypertension; role of genetic variation at the catecholamine storage vesicle protein chromogranin B. Circ Cardiovasc Genet. 2009 Feb; 2(1):46-56. PMID: 20011129.
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    205. Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork N, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 2009 May; 136(5):1585-92. PMID: 19208353; PMCID: PMC3397140.
    206. Torkamani A, Schork N. Pathway and network analysis with high-density allelic association data. Methods Mol Biol. 2009; 563:289-301. PMID: 19597792.
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    207. Ursin G, Lillie EO, Lee E, Cockburn M, Schork N, Cozen W, Parisky YR, Hamilton AS, Astrahan MA, Mack T. The relative importance of genetics and environment on mammographic density. Cancer Epidemiol Biomarkers Prev. 2009 Jan; 18(1):102-12. PMID: 19124487.
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    208. Bhatnagar V, O'Connor DT, Brophy VH, Schork N, Richard E, Salem RM, Nievergelt CM, Bakris GL, Middleton JP, Norris KC, Wright J, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS. G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. Am J Hypertens. 2009 Mar; 22(3):332-8. PMID: 19119263; PMCID: PMC2715837.
    209. Torkamani A, Verkhivker G, Schork N. Cancer driver mutations in protein kinase genes. Cancer Lett. 2009 Aug 28; 281(2):117-27. PMID: 19081671; PMCID: PMC2905872.
    210. Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork N, Taupenot L, Ziegler MG, O'Connor DT. Adrenergic polymorphism and the human stress response. Ann N Y Acad Sci. 2008 Dec; 1148:282-96. PMID: 19120120; PMCID: PMC2743085.
    211. Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork N, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT. Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion. J Am Coll Cardiol. 2008 Oct 28; 52(18):1468-81. PMID: 19017515; PMCID: PMC2659417.
    212. Zhou D, Xue J, Lai JC, Schork N, White KP, Haddad GG. Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet. 2008 Oct; 4(10):e1000221. PMID: 18927626; PMCID: PMC2556400.
    213. Torkamani A, Topol EJ, Schork N. Pathway analysis of seven common diseases assessed by genome-wide association. Genomics. 2008 Nov; 92(5):265-72. PMID: 18722519; PMCID: PMC2602835.
    214. Mathews CA, Greenwood T, Wessel J, Azzam A, Garrido H, Chavira DA, Chandavarkar U, Bagnarello M, Stein M, Schork N. Evidence for a heritable unidimensional symptom factor underlying obsessionality. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 05; 147B(6):676-85. PMID: 18163383.
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    215. Mossé YP, Laudenslager M, Longo L, Cole KA, Wood A, Attiyeh EF, Laquaglia MJ, Sennett R, Lynch JE, Perri P, Laureys G, Speleman F, Kim C, Hou C, Hakonarson H, Torkamani A, Schork N, Brodeur GM, Tonini GP, Rappaport E, Devoto M, Maris JM. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature. 2008 Oct 16; 455(7215):930-5. PMID: 18724359; PMCID: PMC2672043.
    216. Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Calkins ME. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biol Psychiatry. 2008 Dec 15; 64(12):1051-9. PMID: 18701089; PMCID: PMC2653714.
    217. Torkamani A, Kannan N, Taylor SS, Schork N. Congenital disease SNPs target lineage specific structural elements in protein kinases. Proc Natl Acad Sci U S A. 2008 Jul 01; 105(26):9011-6. PMID: 18579784; PMCID: PMC2449356.
    218. Gerhard T, Gong Y, Beitelshees AL, Mao X, Lobmeyer MT, Cooper-DeHoff RM, Langaee TY, Schork N, Shriver MD, Pepine CJ, Johnson JA. Alpha-adducin polymorphism associated with increased risk of adverse cardiovascular outcomes: results from GENEtic Substudy of the INternational VErapamil SR-trandolapril STudy (INVEST-GENES). Am Heart J. 2008 Aug; 156(2):397-404. PMID: 18657677; PMCID: PMC2547143.
    219. Torkamani A, Schork N. Predicting functional regulatory polymorphisms. Bioinformatics. 2008 Aug 15; 24(16):1787-92. PMID: 18562267.
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    220. Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork N, Lavine JE, Taylor S, Newbury RO, Kolodner RD, Hoffman HM. Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 2008 Aug; 135(2):429-37. PMID: 18572020; PMCID: PMC2574708.
    221. Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Green MF. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2008 Aug; 103(1-3):218-28. PMID: 18406578; PMCID: PMC2529172.
    222. Evans LM, Akiskal HS, Greenwood TA, Nievergelt CM, Keck PE, McElroy SL, Sadovnick AD, Remick RA, Schork N, Kelsoe JR. Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families. Am J Med Genet B Neuropsychiatr Genet. 2008 Apr 05; 147(3):326-32. PMID: 18081158.
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    223. Torkamani A, Schork N. Prediction of cancer driver mutations in protein kinases. Cancer Res. 2008 Mar 15; 68(6):1675-82. PMID: 18339846.
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    224. Malo N, Libiger O, Schork N. Accommodating linkage disequilibrium in genetic-association analyses via ridge regression. Am J Hum Genet. 2008 Feb; 82(2):375-85. PMID: 18252218; PMCID: PMC2427310.
    225. Braff DL, Greenwood TA, Swerdlow NR, Light GA, Schork N. Advances in endophenotyping schizophrenia. World Psychiatry. 2008 Feb; 7(1):11-8. PMID: 18458787; PMCID: PMC2359727.
    226. Salem RM, Cadman PE, Chen Y, Rao F, Wen G, Hamilton BA, Rana BK, Smith DW, Stridsberg M, Ward HJ, Mahata M, Mahata SK, Bowden DW, Hicks PJ, Freedman BI, Schork N, O'Connor DT. Chromogranin A polymorphisms are associated with hypertensive renal disease. J Am Soc Nephrol. 2008 Mar; 19(3):600-14. PMID: 18235090; PMCID: PMC2391050.
    227. Fung MM, Nguyen C, Mehtani P, Salem RM, Perez B, Thomas B, Das M, Schork N, Mahata SK, Ziegler MG, O'Connor DT. Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans. Circulation. 2008 Jan 29; 117(4):517-25. PMID: 18180394; PMCID: PMC2628716.
    228. Schork N, Wessel J, Malo N. DNA sequence-based phenotypic association analysis. Adv Genet. 2008; 60:195-217. PMID: 18358322.
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    229. Rice TK, Schork N, Rao DC. Methods for handling multiple testing. Adv Genet. 2008; 60:293-308. PMID: 18358325.
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    230. Zhou D, Wang J, Zapala MA, Xue J, Schork N, Haddad GG. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiol Genomics. 2008 Feb 19; 32(3):370-9. PMID: 18056785.
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    231. Barrett TB, Emberton JE, Nievergelt CM, Liang SG, Hauger RL, Eskin E, Schork N, Kelsoe JR. Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation. Psychiatr Genet. 2007 Dec; 17(6):315-22. PMID: 18075471.
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    232. Corby PM, Bretz WA, Hart TC, Schork N, Wessel J, Lyons-Weiler J, Paster BJ. Heritability of oral microbial species in caries-active and caries-free twins. Twin Res Hum Genet. 2007 Dec; 10(6):821-8. PMID: 18179393; PMCID: PMC3148892.
    233. Wessel J, Schork AJ, Tiwari HK, Schork N. Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypes. Genet Epidemiol. 2007 Nov; 31(7):789-96. PMID: 17549743.
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    234. Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Schork N. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry. 2007 Nov; 64(11):1242-50. PMID: 17984393.
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    235. Bhatnagar V, O'Connor DT, Schork N, Salem RM, Nievergelt CM, Rana BK, Smith DW, Bakris GL, Middleton JP, Norris KC, Wright JT, Cheek D, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS. Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. J Hypertens. 2007 Oct; 25(10):2082-92. PMID: 17885551; PMCID: PMC2792638.
    236. Torkamani A, Schork N. Accurate prediction of deleterious protein kinase polymorphisms. Bioinformatics. 2007 Nov 01; 23(21):2918-25. PMID: 17855419.
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    237. Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork N, Ziegler MG, O'Connor DT. Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk. J Clin Invest. 2007 Sep; 117(9):2658-71. PMID: 17717598; PMCID: PMC1950457.
    238. Beitelshees AL, Gong Y, Wang D, Schork N, Cooper-Dehoff RM, Langaee TY, Shriver MD, Sadee W, Knot HJ, Pepine CJ, Johnson JA. KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenet Genomics. 2007 Sep; 17(9):719-29. PMID: 17700361; PMCID: PMC2713584.
    239. Mosley CA, Taupenot L, Biswas N, Taulane JP, Olson NH, Vaingankar SM, Wen G, Schork N, Ziegler MG, Mahata SK, O'Connor DT. Biogenesis of the secretory granule: chromogranin A coiled-coil structure results in unusual physical properties and suggests a mechanism for granule core condensation. Biochemistry. 2007 Sep 25; 46(38):10999-1012. PMID: 17718510.
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    240. Libiger O, Schork N. A simulation-based analysis of chromosome segment sharing among a group of arbitrarily related individuals. Eur J Hum Genet. 2007 Dec; 15(12):1260-8. PMID: 17700628.
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    241. Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork N, Taupenot L, Ziegler MG, O'Connor DT. Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. Circulation. 2007 Aug 28; 116(9):993-1006. PMID: 17698732.
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    242. Knöll R, Postel R, Wang J, Krätzner R, Hennecke G, Vacaru AM, Vakeel P, Schubert C, Murthy K, Rana BK, Kube D, Knöll G, Schäfer K, Hayashi T, Holm T, Kimura A, Schork N, Toliat MR, Nürnberg P, Schultheiss HP, Schaper W, Schaper J, Bos E, Den Hertog J, van Eeden FJ, Peters PJ, Hasenfuss G, Chien KR, Bakkers J. Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation. 2007 Jul 31; 116(5):515-25. PMID: 17646580.
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    243. Greenhall JA, Zapala MA, Cáceres M, Libiger O, Barlow C, Schork N, Lockhart DJ. Detecting genetic variation in microarray expression data. Genome Res. 2007 Aug; 17(8):1228-35. PMID: 17609390; PMCID: PMC1933513.
    244. Wen G, Wessel J, Zhou W, Ehret GB, Rao F, Stridsberg M, Mahata SK, Gent PM, Das M, Cooper RS, Chakravarti A, Zhou H, Schork N, O'connor DT, Hamilton BA. An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension. Hum Mol Genet. 2007 Jul 15; 16(14):1752-64. PMID: 17584765; PMCID: PMC2695823.
    245. Torkamani A, Schork N. Distribution analysis of nonsynonymous polymorphisms within the human kinase gene family. Genomics. 2007 Jul; 90(1):49-58. PMID: 17498919.
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    246. Wessel J, Zapala MA, Schork N. Accommodating pathway information in expression quantitative trait locus analysis. Genomics. 2007 Jul; 90(1):132-42. PMID: 17493783.
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    247. Braff D, Schork N, Gottesman II. Endophenotyping schizophrenia. Am J Psychiatry. 2007 May; 164(5):705-7. PMID: 17475726.
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    248. Stein MB, Schork N, Gelernter J. Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology. 2008 Jan; 33(2):312-9. PMID: 17460615.
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    249. Lillie EO, Mahata M, Khandrika S, Rao F, Bundey RA, Wen G, Chen Y, Taupenot L, Smith DW, Mahata SK, Ziegler MG, Cockburn M, Schork N, O'Connor DT. Heredity of endothelin secretion: human twin studies reveal the influence of polymorphism at the chromogranin A locus, a novel determinant of endothelial function. Circulation. 2007 May 01; 115(17):2282-91. PMID: 17438153.
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    250. Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork N, Hamilton BA, Ziegler MG, Mahata SK, O'Connor DT. Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension. Circulation. 2007 May 01; 115(17):2271-81. PMID: 17438154.
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    251. Gong Y, Beitelshees AL, Wessel J, Langaee TY, Schork N, Johnson JA. Single nucleotide polymorphism discovery and haplotype analysis of Ca2+-dependent K+ channel beta-1 subunit. Pharmacogenet Genomics. 2007 Apr; 17(4):267-75. PMID: 17496725; PMCID: PMC2713575.
    252. Greenwood TA, Libiger O, Kardia S, Hanis C, Morrison AC, Gu CC, Rice T, Miller M, Turner ST, Myers RH, Grove J, Hsiao CF, Weder AB, Schork N. Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program. Genet Epidemiol. 2007 Apr; 31(3):195-210. PMID: 17266112.
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    253. Gu CC, Hunt SC, Kardia S, Turner ST, Chakravarti A, Schork N, Olshen R, Curb D, Jaquish C, Boerwinkle E, Rao DC. An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP). Hum Genet. 2007 Jun; 121(5):577-90. PMID: 17372766.
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    254. Rao F, Wessel J, Wen G, Zhang L, Rana BK, Kennedy BP, Greenwood TA, Salem RM, Chen Y, Khandrika S, Hamilton BA, Smith DW, Holstein-Rathlou NH, Ziegler MG, Schork N, O'Connor DT. Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism. Hypertension. 2007 May; 49(5):1015-31. PMID: 17353515.
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    255. Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2007 May; 92(1-3):237-51. PMID: 17346930; PMCID: PMC2039885.
    256. Mathews CA, Nievergelt CM, Azzam A, Garrido H, Chavira DA, Wessel J, Bagnarello M, Reus VI, Schork N. Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 05; 144B(2):174-82. PMID: 17290446.
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    257. Nievergelt CM, Libiger O, Schork N. Generalized analysis of molecular variance. PLoS Genet. 2007 Apr 06; 3(4):e51. PMID: 17411342; PMCID: PMC1847693.
    258. Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, Ziegler MG, Witztum JL, Schork N, Schmid-Schönbein GW, O'Connor DT. C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci. J Hypertens. 2007 Feb; 25(2):329-43. PMID: 17211240.
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    259. Glatt SJ, Chayavichitsilp P, Depp C, Schork N, Jeste DV. Successful aging: from phenotype to genotype. Biol Psychiatry. 2007 Aug 15; 62(4):282-93. PMID: 17210144.
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    260. Hovatta I, Zapala MA, Broide RS, Schadt EE, Libiger O, Schork N, Lockhart DJ, Barlow C. DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biol. 2007; 8(2):R25. PMID: 17324278; PMCID: PMC1852412.
    261. Luo X, Kranzler HR, Zuo L, Wang S, Schork N, Gelernter J. Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans. Hum Mol Genet. 2007 Feb 15; 16(4):380-90. PMID: 17185388; PMCID: PMC1853246.
    262. Rana BK, Insel PA, Payne SH, Abel K, Beutler E, Ziegler MG, Schork N, O'Connor DT. Population-based sample reveals gene-gender interactions in blood pressure in White Americans. Hypertension. 2007 Jan; 49(1):96-106. PMID: 17159089.
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    263. Zapala MA, Schork N. Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19430-5. PMID: 17146048; PMCID: PMC1748243.
    264. Braff DL, Freedman R, Schork N, Gottesman II. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull. 2007 Jan; 33(1):21-32. PMID: 17088422; PMCID: PMC2632293.
    265. Schork N, Greenwood TA, Braff DL. Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research. Schizophr Bull. 2007 Jan; 33(1):95-104. PMID: 17035359; PMCID: PMC2632283.
    266. Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull. 2007 Jan; 33(1):33-48. PMID: 17035358; PMCID: PMC2632302.
    267. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork N, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res. 2007 Jan; 89(1-3):320-9. PMID: 17023145.
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    268. Wessel J, Schork N. Generalized genomic distance-based regression methodology for multilocus association analysis. Am J Hum Genet. 2006 Nov; 79(5):792-806. PMID: 17033957; PMCID: PMC1698575.
    269. Niculescu AB, Lulow LL, Ogden CA, Le-Niculescu H, Salomon DR, Schork N, Caligiuri MP, Lohr JB. PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes. Am J Med Genet B Neuropsychiatr Genet. 2006 Sep 05; 141B(6):653-62. PMID: 16838358.
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    270. Bretz WA, Corby PM, Melo MR, Coelho MQ, Costa SM, Robinson M, Schork N, Drewnowski A, Hart TC. Heritability estimates for dental caries and sucrose sweetness preference. Arch Oral Biol. 2006 Dec; 51(12):1156-60. PMID: 16934741.
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    271. Tang H, Jorgenson E, Gadde M, Kardia SL, Rao DC, Zhu X, Schork N, Hanis CL, Risch N. Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet. 2006 Jul; 119(6):624-33. PMID: 16738946.
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    272. Luo X, Kranzler HR, Zuo L, Wang S, Schork N, Gelernter J. Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am J Hum Genet. 2006 Jun; 78(6):973-87. PMID: 16685648; PMCID: PMC1474098.
    273. Mathews CA, Jang KL, Herrera LD, Lowe TL, Budman CL, Erenberg G, Naarden A, Bruun RD, Schork N, Freimer NB, Reus VI. Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populations. Biol Psychiatry. 2007 Feb 01; 61(3):292-300. PMID: 16581034.
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    274. Nievergelt CM, Kripke DF, Barrett TB, Burg E, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Schork N, Kelsoe JR. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 05; 141B(3):234-41. PMID: 16528748; PMCID: PMC2651679.
    275. Seasholtz TM, Wessel J, Rao F, Rana BK, Khandrika S, Kennedy BP, Lillie EO, Ziegler MG, Smith DW, Schork N, Brown JH, O'Connor DT. Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity. Hypertension. 2006 May; 47(5):937-47. PMID: 16585408.
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    276. Chang YP, Kim JD, Schwander K, Rao DC, Miller MB, Weder AB, Cooper RS, Schork N, Province MA, Morrison AC, Kardia SL, Quertermous T, Chakravarti A. The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program. Eur J Hum Genet. 2006 Apr; 14(4):469-77. PMID: 16493446.
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    277. Greenwood TA, Rao F, Stridsberg M, Mahapatra NR, Mahata M, Lillie EO, Mahata SK, Taupenot L, Schork N, O'Connor DT. Pleiotropic effects of novel trans-acting loci influencing human sympathochromaffin secretion. Physiol Genomics. 2006 May 16; 25(3):470-9. PMID: 16554546.
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    278. Libiger O, Schork N. Simulation-based homozygosity mapping with the GAW14 COGA dataset on alcoholism. BMC Genet. 2005 Dec 30; 6 Suppl 1:S35. PMID: 16451645; PMCID: PMC1866750.
    279. Stein MB, Fallin MD, Schork N, Gelernter J. COMT polymorphisms and anxiety-related personality traits. Neuropsychopharmacology. 2005 Nov; 30(11):2092-102. PMID: 15956988.
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    280. Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork N, Lavine JE. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005 Sep; 42(3):641-9. PMID: 16116629.
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    281. Murthy KK, Mahboubi VS, Santiago A, Barragan MT, Knöll R, Schultheiss HP, O'Connor DT, Schork N, Rana BK. Assessment of multiple displacement amplification for polymorphism discovery and haplotype determination at a highly polymorphic locus, MC1R. Hum Mutat. 2005 Aug; 26(2):145-52. PMID: 15957185.
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    282. Bao X, Mills PJ, Rana BK, Dimsdale JE, Schork N, Smith DW, Rao F, Milic M, O'Connor DT, Ziegler MG. Interactive effects of common beta2-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function. Hypertension. 2005 Aug; 46(2):301-7. PMID: 16027244.
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    283. Etzel JP, Rana BK, Wen G, Parmer RJ, Schork N, O'Connor DT, Insel PA. Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response. Hypertension. 2005 Jun; 45(6):1207-13. PMID: 15920038.
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    284. King D, Etzel JP, Chopra S, Smith J, Cadman PE, Rao F, Funk SD, Rana BK, Schork N, Insel PA, O'Connor DT. Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: Biphasic influence of dose, age, gender, and receptor genotype. Clin Pharmacol Ther. 2005 May; 77(5):388-403. PMID: 15900285.
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    285. Friese RS, Mahboubi P, Mahapatra NR, Mahata SK, Schork N, Schmid-Schönbein GW, O'Connor DT. Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension. Am J Hypertens. 2005 May; 18(5 Pt 1):633-52. PMID: 15882546.
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    286. Salem RM, Wessel J, Schork N. A comprehensive literature review of haplotyping software and methods for use with unrelated individuals. Hum Genomics. 2005 Mar; 2(1):39-66. PMID: 15814067; PMCID: PMC3525117.
    287. An P, Freedman BI, Hanis CL, Chen YD, Weder AB, Schork N, Boerwinkle E, Province MA, Hsiung CA, Wu X, Quertermous T, Rao DC. Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. Diabetes. 2005 Mar; 54(3):909-14. PMID: 15734873.
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    288. Nievergelt CM, Schork N. Admixture mapping as a gene discovery approach for complex human traits and diseases. Curr Hypertens Rep. 2005 Feb; 7(1):31-7. PMID: 15683584.
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    289. Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork N, Cummings SR, Phong A, Burchard EG, Harris TB, Psaty BM, Kwok PY. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet. 2005 Mar; 76(3):463-77. PMID: 15660291; PMCID: PMC1196398.
    290. Soares ML, Coelho T, Sousa A, Batalov S, Conceição I, Sales-Luís ML, Ritchie MD, Williams SM, Nievergelt CM, Schork N, Saraiva MJ, Buxbaum JN. Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease. Hum Mol Genet. 2005 Feb 15; 14(4):543-53. PMID: 15649951.
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    291. Mustanski BS, Dupree MG, Nievergelt CM, Bocklandt S, Schork N, Hamer DH. A genomewide scan of male sexual orientation. Hum Genet. 2005 Mar; 116(4):272-8. PMID: 15645181.
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    292. Jorgenson E, Tang H, Gadde M, Province M, Leppert M, Kardia S, Schork N, Cooper R, Rao DC, Boerwinkle E, Risch N. Ethnicity and human genetic linkage maps. Am J Hum Genet. 2005 Feb; 76(2):276-90. PMID: 15627237; PMCID: PMC1196373.
    293. Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A, Pankow JS, Province MA, Hunt SC, Boerwinkle E, Schork N, Risch NJ. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet. 2005 Feb; 76(2):268-75. PMID: 15625622; PMCID: PMC1196372.
    294. Zhang L, Rao F, Wessel J, Kennedy BP, Rana BK, Taupenot L, Lillie EO, Cockburn M, Schork N, Ziegler MG, O'Connor DT. Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiol Genomics. 2004 Nov 17; 19(3):277-91. PMID: 15367723.
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    295. Stein MB, Schork N, Gelernter J. A polymorphism of the beta1-adrenergic receptor is associated with low extraversion. Biol Psychiatry. 2004 Aug 15; 56(4):217-24. PMID: 15312808.
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    296. Le Corre P, Parmer RJ, Kailasam MT, Kennedy BP, Skaar TP, Ho H, Leverge R, Smith DW, Ziegler MG, Insel PA, Schork N, Flockhart DA, O'connor DT. Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism. Clin Pharmacol Ther. 2004 Aug; 76(2):139-53. PMID: 15289791.
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    297. Greenwood TA, Rana BK, Schork N. Human haplotype block sizes are negatively correlated with recombination rates. Genome Res. 2004 Jul; 14(7):1358-61. PMID: 15231751; PMCID: PMC442152.
    298. Greenwood TA, Cadman PE, Stridsberg M, Nguyen S, Taupenot L, Schork N, O'Connor DT. Genome-wide linkage analysis of chromogranin B expression in the CEPH pedigrees: implications for exocytotic sympathochromaffin secretion in humans. Physiol Genomics. 2004 Jun 17; 18(1):119-27. PMID: 15138309.
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    299. Fries RS, Mahboubi P, Mahapatra NR, Mahata SK, Schork N, Schmid-Schoenbein GW, O'Connor DT. Neuroendocrine transcriptome in genetic hypertension: multiple changes in diverse adrenal physiological systems. Hypertension. 2004 Jun; 43(6):1301-11. PMID: 15166183.
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    300. Nievergelt CM, Smith DW, Kohlenberg JB, Schork N. Large-scale integration of human genetic and physical maps. Genome Res. 2004 Jun; 14(6):1199-205. PMID: 15140834; PMCID: PMC419799.
    301. Schork N, Greenwood TA. Inherent bias toward the null hypothesis in conventional multipoint nonparametric linkage analysis. Am J Hum Genet. 2004 Feb; 74(2):306-16. PMID: 14732904; PMCID: PMC1181928.
    302. Wen G, Mahata SK, Cadman P, Mahata M, Ghosh S, Mahapatra NR, Rao F, Stridsberg M, Smith DW, Mahboubi P, Schork N, O'Connor DT, Hamilton BA. Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology. Am J Hum Genet. 2004 Feb; 74(2):197-207. PMID: 14740315; PMCID: PMC1181918.
    303. Broeckel U, Schork N. Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping. J Physiol. 2004 Jan 01; 554(Pt 1):40-5. PMID: 14678489; PMCID: PMC1664744.
    304. Conti LH, Jirout M, Breen L, Vanella JJ, Schork N, Printz MP. Identification of quantitative trait Loci for anxiety and locomotion phenotypes in rat recombinant inbred strains. Behav Genet. 2004 Jan; 34(1):93-103. PMID: 14739700.
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    305. Gold DA, Baek SH, Schork N, Rose DW, Larsen DD, Sachs BD, Rosenfeld MG, Hamilton BA. RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron. 2003 Dec 18; 40(6):1119-31. PMID: 14687547; PMCID: PMC2717708.
    306. Bretz WA, Corby P, Schork N, Hart TC. Evidence of a contribution of genetic factors to dental caries risk. J Evid Based Dent Pract. 2003 Dec; 3(4):185-189. PMID: 22287938.
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    307. Jirout M, Krenová D, Kren V, Breen L, Pravenec M, Schork N, Printz MP. A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set. Mamm Genome. 2003 Aug; 14(8):537-46. PMID: 12925886.
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    308. Thiel BA, Chakravarti A, Cooper RS, Luke A, Lewis S, Lynn A, Tiwari H, Schork N, Weder AB. A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans. Am J Hypertens. 2003 Feb; 16(2):151-3. PMID: 12559684.
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    309. Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork N, Omens JH, McCulloch AD, Kimura A, Gregorio CC, Poller W, Schaper J, Schultheiss HP, Chien KR. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell. 2002 Dec 27; 111(7):943-55. PMID: 12507422.
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    310. Schork N, Gardner JP, Zhang L, Fallin D, Thiel B, Jakubowski H, Aviv A. Genomic association/linkage of sodium lithium countertransport in CEPH pedigrees. Hypertension. 2002 Nov; 40(5):619-28. PMID: 12411453.
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    311. Kotchen TA, Broeckel U, Grim CE, Hamet P, Jacob H, Kaldunski ML, Kotchen JM, Schork N, Tonellato PJ, Cowley AW. Identification of hypertension-related QTLs in African American sib pairs. Hypertension. 2002 Nov; 40(5):634-9. PMID: 12411455.
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    312. Larribe F, Lessard S, Schork N. Gene mapping via the ancestral recombination graph. Theor Popul Biol. 2002 Sep; 62(2):215-29. PMID: 12167358.
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    313. Schork N. Power calculations for genetic association studies using estimated probability distributions. Am J Hum Genet. 2002 Jun; 70(6):1480-9. PMID: 11992254; PMCID: PMC379135.
    314. Shaw SH, Hutchison D, Saiz R, Abel K, DeLisi LE, Schork N, Sherrington R. Evaluation of linkage disequilibrium between chromosome 22q11 single nucleotide polymorphisms in a large outbred population. Am J Med Genet. 2002 Mar 08; 114(2):205-13. PMID: 11857583.
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    315. Nath SK, Chakravarti A, Chen CH, Cooper R, Weder A, Schork N. Segregation analysis of blood pressure and body mass index in a rural US community. Hum Biol. 2002 Feb; 74(1):11-23. PMID: 11931572.
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    316. Morrison SJ, Qian D, Jerabek L, Thiel BA, Park IK, Ford PS, Kiel MJ, Schork N, Weissman IL, Clarke MF. A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol. 2002 Jan 15; 168(2):635-42. PMID: 11777956.
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