Rick Friedman

Title(s)Professor, Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    The genetics of functional decline in the aging vestibular system: A GWAS and gene expression analysis in aging mice and humans
    NIH R01DC020052Sep 1, 2021 - May 31, 2026
    Role: Principal Investigator
    The genetic basis for age-related hearing loss in outbred mice
    NIH R01DC018566Sep 18, 2020 - Aug 31, 2025
    Role: Principal Investigator
    High-Resolution Mapping of Susceptibility Genes for NIHL
    NIH R01DC010856Feb 1, 2011 - Jan 31, 2017
    Role: Principal Investigator
    Genetic Analysis of Age Related Hearing Impairment
    NIH R01DC010215Sep 3, 2009 - Jul 31, 2012
    Role: Principal Investigator
    Study of a genetic network involved in ear development
    NIH R01DC004796Sep 28, 2001 - Aug 31, 2007
    Role: Principal Investigator
    MOLECULAR GENETICS OF INNER EAR DEVELOPMENT
    NIH K08DC000119Jan 1, 1997 - Dec 31, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cochlear T2 Signal May Predict Hearing Outcomes After Resection of Acoustic Neuroma. Otol Neurotol. 2021 Oct 01; 42(9):1399-1407. Tawfik KO, McDonald M, Ren Y, Moshtaghi O, Schwartz MS, Friedman RA. PMID: 34121085.
      View in: PubMed   Mentions:    Fields:    
    2. Large-scale phenotyping of ABR P1-N1 amplitudes before and after exposure to noise in 69 strains of mice. Mamm Genome. 2021 Sep 06. Lavinsky J, Mendonça A, Bressan M, da Silva VAR, Kasperbauer G, Wang J, Salehi P, Boussaty EC, Friedman RA. PMID: 34487237.
      View in: PubMed   Mentions:    Fields:    
    3. The Relationship Between the Functional Gait Assessment and Quality-of-Life Data in Patients Undergoing Vestibular Schwannoma Resection. Otol Neurotol. 2021 08 01; 42(7):1074-1080. Said M, Lee J, Moshtaghi O, Saliba J, Richardson AJW, Ngo V, Mehranpour P, Schwartz MS, Friedman RA. PMID: 33741817.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Hearing loss and tinnitus: association studies for complex-hearing disorders in mouse and man. Hum Genet. 2021 Jul 27. Boussaty EC, Friedman RA, Million Veteran Program , Clifford RE. PMID: 34318347.
      View in: PubMed   Mentions:    Fields:    
    5. Noise Exposure and Distortion Product Otoacoustic Emission Suprathreshold Amplitudes: A Genome-Wide Association Study. Audiol Neurootol. 2021 Jul 19; 1-9. Lavinsky J, Kasperbauer G, Bento RF, Mendonça A, Wang J, Crow AL, Allayee H, Friedman RA. PMID: 34280920.
      View in: PubMed   Mentions:    Fields:    
    6. Factors Associated With Unilateral Hearing Loss and Impact on Communication in US Adults. Otolaryngol Head Neck Surg. 2021 Mar 23; 194599821995485. Choi JS, Wu F, Park S, Friedman RA, Kari E, Volker CCJ. PMID: 33752481.
      View in: PubMed   Mentions:    Fields:    
    7. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss. JCI Insight. 2020 12 03; 5(23). Cui L, Zheng J, Zhao Q, Chen JR, Liu H, Peng G, Wu Y, Chen C, He Q, Shi H, Yin S, Friedman RA, Chen Y, Guan MX. PMID: 33268592.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Clinical Predictors of Facial Nerve Outcomes After Surgical Resection of Vestibular Schwannoma. Otolaryngol Head Neck Surg. 2021 05; 164(5):1085-1093. Ren Y, MacDonald BV, Tawfik KO, Schwartz MS, Friedman RA. PMID: 33048002.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Middle fossa approach for a pediatric facial nerve meningioma. J Neurosurg Pediatr. 2020 Aug 28; 1-5. Rennert RC, Levy DM, Plonsker J, Steinberg JA, Friedman RA, Crawford JR, Levy ML. PMID: 32858509.
      View in: PubMed   Mentions:    Fields:    
    10. The Genetics of Variation of the Wave 1 Amplitude of the Mouse Auditory Brainstem Response. J Assoc Res Otolaryngol. 2020 08; 21(4):323-336. Boussaty EC, Gillard D, Lavinsky J, Salehi P, Wang J, Mendonça A, Allayee H, Manor U, Friedman RA. PMID: 32757112.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    11. Predicting Functional Outcomes and Length of Stay Following Acoustic Neuroma Resection. Laryngoscope. 2021 03; 131(3):644-648. Moshtaghi O, Saliba J, Gupta M, Mehranpour P, Tawfik KO, Ren Y, Schwartz MS, Friedman RA. PMID: 32757415.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations. Ear Hear. 2020 Jul/Aug; 41(4):983-989. Kari E, Llaci L, Go JL, Naymik M, Knowles JA, Leal SM, Rangasamy S, Huentelman MJ, Liang W, Friedman RA, Schrauwen I. PMID: 31985533.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. What Genes Can Tell: A Closer Look at Vestibular Schwannoma. Otol Neurotol. 2020 04; 41(4):522-529. Aaron KA, Manojlovic Z, Tu N, Xu Y, Jin Y, Chang S, Kwok E, Webb M, Hurth K, Friedman RA. PMID: 32176142.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. The Direct Costs of Microsurgical Resection of Vestibular Schwannomas. Otol Neurotol. 2020 03; 41(3):397-402. Saliba J, Mohammadzadeh A, Tawfik KO, Carriere JS, Schwartz MS, Nguyen QT, Friedman RA. PMID: 31868780.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. A de novo SIX1 variant in a patient with a rare nonsyndromic cochleovestibular nerve abnormality, cochlear hypoplasia, and bilateral sensorineural hearing loss. Mol Genet Genomic Med. 2019 12; 7(12):e995. Kari E, Llaci L, Go JL, Naymik M, Knowles JA, Leal SM, Rangasamy S, Huentelman MJ, Friedman RA, Schrauwen I. PMID: 31595699.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Tophaceous Gout of the Middle Ear: Case Reports and Review of the Literature. Audiol Neurootol. 2019; 24(2):51-55. Saliba J, Sakano H, Friedman RA, Harris JP. PMID: 31167187.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. The α2 chain of type IX collagen is essential for type IX collagen biosynthesis. . 2019 08; 179(8):1672-1677. Balasubramanian K, Weis M, Eyre DR, Martin J, Ortiz-Sanchez J, Duran I, Vangala S, Wang J, Friedman RA, Krakow D, Cohn DH. PMID: 31161720.
      View in: PubMed   Mentions:
    18. Advances in understanding of presbycusis. J Neurosci Res. 2020 09; 98(9):1685-1697. Tawfik KO, Klepper K, Saliba J, Friedman RA. PMID: 30950547.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    19. Cochlear FLAIR Signal Changes in Hearing Preservation Vestibular Schwannoma Surgery. Otol Neurotol. 2019 03; 40(3):375-383. Tu NC, Bobarnac Dogaru G, Huang P, Kim J, Diegnan B, Go JL, Friedman RA. PMID: 30664035.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Intentional Subtotal Resection of Vestibular Schwannoma: A Reexamination. J Neurol Surg B Skull Base. 2020 Apr; 81(2):136-141. Strickland BA, Ravina K, Rennert RC, Jackanich A, Aaron K, Bakhsheshian J, Russin JJ, Friedman RA, Giannotta SL. PMID: 32206531.
      View in: PubMed   Mentions:
    21. Increased Hospital Surgical Volume Reduces Rate of 30- and 90-Day Readmission After Acoustic Neuroma Surgery. Neurosurgery. 2019 03 01; 84(3):726-732. Babadjouni R, Wen T, Donoho DA, Buchanan IA, Cen SY, Friedman RA, Amar A, Russin JJ, Giannotta SL, Mack WJ, Attenello FJ. PMID: 29889284.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Hearing Preservation in Vestibular Schwannoma Surgery. J Neurol Surg B Skull Base. 2019 Apr; 80(2):149-155. Saliba J, Friedman RA, Cueva RA. PMID: 30931222.
      View in: PubMed   Mentions:
    23. De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness. Hum Genet. 2018 Jul; 137(6-7):459-470. Schrauwen I, Kari E, Mattox J, Llaci L, Smeeton J, Naymik M, Raible DW, Knowles JA, Crump JG, Huentelman MJ, Friedman RA. PMID: 29955957.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    24. Age-related hearing loss: Unraveling the pieces. Laryngoscope Investig Otolaryngol. 2018 Apr; 3(2):68-72. Tu NC, Friedman RA. PMID: 29721536.
      View in: PubMed   Mentions:
    25. Prevalence of Hearing Loss and Hearing Care Use Among Asian Americans: A Nationally Representative Sample. Otol Neurotol. 2018 02; 39(2):158-167. Choi JS, Kari E, Friedman RA, Fisher LM. PMID: 29315179.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct; 13(10):e1007048. Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA. PMID: 29059194.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    27. Compound heterozygous mutations in MASP1 in a deaf child with absent cochlear nerves. Neurol Genet. 2017 Jun; 3(3):e153. Kari E, Schrauwen I, Llaci L, Fisher LM, Go JL, Naymik M, Knowles JA, Huentelman MJ, Friedman RA. PMID: 28534045.
      View in: PubMed   Mentions:
    28. Solitary Plasmacytoma in the Internal Auditory Canal and Cerebellopontine Angle Mimicking Meningioma. Otol Neurotol. 2016 Dec; 37(10):e400-e401. Lavinsky J, Aaron KA, Christian E, Go JL, Hurth K, Giannotta SL, Friedman RA. PMID: 26457817.
      View in: PubMed   Mentions: 2     Fields:    
    29. The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda). 2016 10 13; 6(10):3219-3228. Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 27520957.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    30. Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. J Assoc Res Otolaryngol. 2016 Oct; 17(5):417-31. Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, Friedman RA. PMID: 27539716.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    31. Large-scale phenotyping of noise-induced hearing loss in 100 strains of mice. Hear Res. 2016 Feb; 332:113-120. Myint A, White CH, Ohmen JD, Li X, Wang J, Lavinsky J, Salehi P, Crow AL, Ohyama T, Friedman RA. PMID: 26706709.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsPHPublic Health
    32. Prognostic implications of and audiometric evidence for hearing fluctuation in Meniere's disease. Laryngoscope. 2015 Dec; 125 Suppl 12:S1-12. Hoa M, Friedman RA, Fisher LM, Derebery MJ. PMID: 26343803.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    33. The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants. G3 (Bethesda). 2015 Sep 04; 5(11):2329-39. Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. PMID: 26342000.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    34. A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear. Hear Res. 2016 Mar; 333:266-274. Schrauwen I, Hasin-Brumshtein Y, Corneveaux JJ, Ohmen J, White C, Allen AN, Lusis AJ, Van Camp G, Huentelman MJ, Friedman RA. PMID: 26341477.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    35. Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss. PLoS Genet. 2015 Jun; 11(6):e1005293. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 26068505.
      View in: PubMed   Mentions: 2     Fields:    
    36. Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. PLoS Genet. 2015 Apr; 11(4):e1005094. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 25880434.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    37. A case report of two different skull base pathologies causing hearing loss in the same ear: vestibular schwannoma and superior semicircular canal dehiscence. Am J Otolaryngol. 2015 May-Jun; 36(3):488-91. Aaron KA, Lavinsky J, Tuchman A, Go JL, Giannotta SL, Friedman RA. PMID: 25720919.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. Eur J Hum Genet. 2015 Jan; 23(1):110-5. Fransen E, Bonneux S, Corneveaux JJ, Schrauwen I, Di Berardino F, White CH, Ohmen JD, Van de Heyning P, Ambrosetti U, Huentelman MJ, Van Camp G, Friedman RA. PMID: 24939585.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    39. Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis. J Assoc Res Otolaryngol. 2014 Jun; 15(3):335-52. Ohmen J, Kang EY, Li X, Joo JW, Hormozdiari F, Zheng QY, Davis RC, Lusis AJ, Eskin E, Friedman RA. PMID: 24570207.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    40. FVB/NJ mice demonstrate a youthful sensitivity to noise-induced hearing loss and provide a useful genetic model for the study of neural hearing loss. Audiol Neurotol Extra. 2014 Jan 01; 4(1):1-11. Ho MK, Li X, Wang J, Ohmen JD, Friedman RA. PMID: 24707282.
      View in: PubMed   Mentions:
    41. Total ossiculoplasty: short- and long-term results using a titanium prosthesis with footplate shoe. Otol Neurotol. 2014 Jan; 35(1):108-13. Fayad JN, Ursick J, Brackmann DE, Friedman RA. PMID: 24270724.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Evaluation of the increased use of partial resection of large vestibular schwanommas: facial nerve outcomes and recurrence/regrowth rates. Otol Neurotol. 2013 Oct; 34(8):1456-64. Schwartz MS, Kari E, Strickland BM, Berliner K, Brackmann DE, House JW, Friedman RA. PMID: 23928516.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    43. Genetic evidence for an ethnic diversity in the susceptibility to Ménière's disease. Otol Neurotol. 2013 Sep; 34(7):1336-41. Ohmen JD, White CH, Li X, Wang J, Fisher LM, Zhang H, Derebery MJ, Friedman RA. PMID: 23598705.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Neuroglial heterotopia of the internal auditory canal. Otol Neurotol. 2013 Apr; 34(3):e22-3. Rizk HG, Lorenz MB, Friedman R. PMID: 23449443.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    45. Imaging case of the month: Fibrous dysplasia causing superior canal dehiscence. Otol Neurotol. 2013 Jan; 34(1):e1-2. Goddard JC, Go JL, Friedman RA. PMID: 23187924.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Oral steroid treatment for hearing improvement in Ménière's disease and endolymphatic hydrops. Otol Neurotol. 2012 Dec; 33(9):1685-91. Fisher LM, Derebery MJ, Friedman RA. PMID: 23047260.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Functional variants of MIF, INFG and TFNA genes are not associated with disease susceptibility or hearing loss progression in patients with Ménière's disease. Eur Arch Otorhinolaryngol. 2013 Mar; 270(4):1521-9. Gázquez I, Moreno A, Requena T, Ohmen J, Santos-Perez S, Aran I, Soto-Varela A, Pérez-Garrigues H, López-Nevot A, Batuecas A, Friedman RA, López-Nevot MA, López-Escamez JA. PMID: 23179933.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    48. Surgical management of endolymphatic sac tumors. J Neurol Surg B Skull Base. 2013 Feb; 74(1):12-9. Friedman RA, Hoa M, Brackmann DE. PMID: 24436884.
      View in: PubMed   Mentions:
    49. GRM7 variants associated with age-related hearing loss based on auditory perception. Hear Res. 2012 Dec; 294(1-2):125-32. Newman DL, Fisher LM, Ohmen J, Parody R, Fong CT, Frisina ST, Mapes F, Eddins DA, Robert Frisina D, Frisina RD, Friedman RA. PMID: 23102807.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    50. Hearing preservation: microsurgery. Curr Opin Otolaryngol Head Neck Surg. 2012 Oct; 20(5):358-66. Kari E, Friedman RA. PMID: 22929113.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    51. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012 Oct; 23(9-10):680-92. Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC. PMID: 22892838.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    52. Hearing preservation with the middle cranial fossa approach for neurofibromatosis type 2. Otol Neurotol. 2011 Dec; 32(9):1530-7. Friedman RA, Goddard JC, Wilkinson EP, Schwartz MS, Slattery WH, Fayad JN, Brackmann DE. PMID: 21986931.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    53. A paradigm shift in salvage surgery for radiated vestibular schwannoma. Otol Neurotol. 2011 Oct; 32(8):1322-8. Friedman RA, Berliner KI, Bassim M, Ursick J, Slattery WH, Schwartz MS, Brackmann DE. PMID: 21897324.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    54. Evolution in the management of facial nerve schwannoma. Laryngoscope. 2011 Oct; 121(10):2065-74. Wilkinson EP, Hoa M, Slattery WH, Fayad JN, Friedman RA, Schwartz MS, Brackmann DE. PMID: 21898431.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    55. Middle fossa decompression for hearing preservation: a review of institutional results and indications. Otol Neurotol. 2011 Aug; 32(6):1017-24. Slattery WH, Hoa M, Bonne N, Friedman RA, Schwartz MS, Fisher LM, Brackmann DE. PMID: 21725256.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    56. Fundal fluid as a predictor of hearing preservation in the middle cranial fossa approach for vestibular schwannoma. Otol Neurotol. 2010 Sep; 31(7):1128-34. Goddard JC, Schwartz MS, Friedman RA. PMID: 20657334.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    57. Radiation therapy for the treatment of vestibular schwannoma: a critical evaluation of the state of the literature. Otol Neurotol. 2010 Jun; 31(4):567-73. Bassim MK, Berliner KI, Fisher LM, Brackmann DE, Friedman RA. PMID: 20300044.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    58. Genome-wide screening for genetic loci associated with noise-induced hearing loss. Mamm Genome. 2009 Apr; 20(4):207-13. White CH, Ohmen JD, Sheth S, Zebboudj AF, McHugh RK, Hoffman LF, Lusis AJ, Davis RC, Friedman RA. PMID: 19337678.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsPHPublic Health
    59. Amino acid 572 in TMC1: hot spot or critical functional residue for dominant mutations causing hearing impairment. J Hum Genet. 2009 Mar; 54(3):188-90. Hilgert N, Monahan K, Kurima K, Li C, Friedman RA, Griffith AJ, Van Camp G. PMID: 19180119.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    60. GRM7 variants confer susceptibility to age-related hearing impairment. Hum Mol Genet. 2009 Feb 15; 18(4):785-96. Friedman RA, Van Laer L, Huentelman MJ, Sheth SS, Van Eyken E, Corneveaux JJ, Tembe WD, Halperin RF, Thorburn AQ, Thys S, Bonneux S, Fransen E, Huyghe J, Pyykkö I, Cremers CW, Kremer H, Dhooge I, Stephens D, Orzan E, Pfister M, Bille M, Parving A, Sorri M, Van de Heyning PH, Makmura L, Ohmen JD, Linthicum FH, Fayad JN, Pearson JV, Craig DW, Stephan DA, Van Camp G. PMID: 19047183.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    61. Mapping of genetic modifiers of Eya1 ( bor/bor ) in CAST/EiJ and BALB/cJ that suppress cochlear aplasia and associated deafness. Mamm Genome. 2008 Sep; 19(9):634-9. Niu H, Li X, Makmura L, Friedman RA. PMID: 18836772.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    62. Acute suppurative otitis media. Ear Nose Throat J. 2008 May; 87(5):250. Wilkinson EP, Friedman RA. PMID: 18572776.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Correction of progressive hearing loss in superior canal dehiscence syndrome. Laryngoscope. 2008 Jan; 118(1):10-3. Wilkinson EP, Liu GC, Friedman RA. PMID: 18090259.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    64. Congenital middle ear cholesteatoma. Ear Nose Throat J. 2007 Nov; 86(11):654. Kutz JW, Friedman RA. PMID: 18225618.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    65. Management of cerebrospinal fluid leaks after acoustic tumor removal. Neurosurgery. 2007 Sep; 61(3 Suppl):35-9; discussion 39-40. Friedman RA, Cullen RD, Ulis J, Brackmann DE. PMID: 17876231.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    66. Surgical management of skull base chondroblastoma. Laryngoscope. 2007 May; 117(5):848-53. Kutz JW, Verma S, Tan HT, Lo WW, Slattery WH, Friedman RA. PMID: 17473681.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    67. Hearing preservation surgery for neurofibromatosis Type 2-related vestibular schwannoma in pediatric patients. J Neurosurg. 2007 Apr; 106(4 Suppl):255-60. Slattery WH, Fisher LM, Hitselberger W, Friedman RA, Brackmann DE. PMID: 17465357.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    68. Effect of ciprodex on graft healing in tympanoplasty. Adv Ther. 2007 Mar-Apr; 24(2):427-35. Starkweather A, Friedman RA. PMID: 17565934.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Controversies in building a management algorithm for vestibular schwannomas. Curr Opin Otolaryngol Head Neck Surg. 2006 Oct; 14(5):305-13. Doherty JK, Friedman RA. PMID: 16974142.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    70. Genetics of hearing loss: Allelism and modifier genes produce a phenotypic continuum. Anat Rec A Discov Mol Cell Evol Biol. 2006 Apr; 288(4):370-81. McHugh RK, Friedman RA. PMID: 16550584.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    71. Identification of two major loci that suppress hearing loss and cochlear dysmorphogenesis in Eya1bor/bor mice. Genomics. 2006 Sep; 88(3):302-8. Niu H, Makmura L, Shen T, Sheth SS, Blair K, Friedman RA. PMID: 16488112.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    72. Surgical salvage after failed irradiation for vestibular schwannoma. Laryngoscope. 2005 Oct; 115(10):1827-32. Friedman RA, Brackmann DE, Hitselberger WE, Schwartz MS, Iqbal Z, Berliner KI. PMID: 16222204.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    73. Intratympanic steroid injection for treatment of idiopathic sudden hearing loss. Otolaryngol Head Neck Surg. 2005 Aug; 133(2):251-9. Slattery WH, Fisher LM, Iqbal Z, Friedman RA, Liu N. PMID: 16087024.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    74. Neurotologic skull base surgery in pediatric patients. Otol Neurotol. 2005 Mar; 26(2):231-6. Cunningham CD, Friedman RA, Brackmann DE, Hitselberger WE, Lin HW. PMID: 15793410.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    75. Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development. Mech Dev. 2005 May; 122(5):625-34. Friedman RA, Makmura L, Biesiada E, Wang X, Keithley EM. PMID: 15817220.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    76. A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10. J Assoc Res Otolaryngol. 2004 Sep; 5(3):295-304. Zhang Y, Knosp BM, Maconochie M, Friedman RA, Smith RJ. PMID: 15492887.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    77. The evolution of surgical approaches for posterior fossa meningiomas. Otol Neurotol. 2004 May; 25(3):394-7. Shen T, Friedman RA, Brackmann DE, Slattery WH, Hitselberger WE, Schwartz MS, Fisher L. PMID: 15129123.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    78. Consensus panel on role of potentially ototoxic antibiotics for topical middle ear use: Introduction, methodology, and recommendations. Otolaryngol Head Neck Surg. 2004 Mar; 130(3 Suppl):S51-6. Roland PS, Stewart MG, Hannley M, Friedman R, Manolidis S, Matz G, Rybak L, Weber P, Owens F. PMID: 15054363.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    79. Animal ototoxicity of topical antibiotics and the relevance to clinical treatment of human subjects. Otolaryngol Head Neck Surg. 2004 Mar; 130(3 Suppl):S57-78. Roland PS, Rybak L, Hannley M, Matz G, Stewart MG, Manolidis S, Friedman R, Weber P, Owens F. PMID: 15054364.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    80. Ototoxicity of ototopical antibiotic drops in humans. Otolaryngol Head Neck Surg. 2004 Mar; 130(3 Suppl):S79-82. Matz G, Rybak L, Roland PS, Hannley M, Friedman R, Manolidis S, Stewart MG, Weber P, Owens F. PMID: 15054365.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    81. Comparative efficacy of aminoglycoside versus fluoroquinolone topical antibiotic drops. Otolaryngol Head Neck Surg. 2004 Mar; 130(3 Suppl):S83-8. Manolidis S, Friedman R, Hannley M, Roland PS, Matz G, Rybak L, Stewart MG, Weber P, Owens F. PMID: 15054366.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    82. Biochemical characterization of the mitochondrial tRNASer(UCN) T7511C mutation associated with nonsyndromic deafness. Nucleic Acids Res. 2004; 32(3):867-77. Li X, Fischel-Ghodsian N, Schwartz F, Yan Q, Friedman RA, Guan MX. PMID: 14960712.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    83. Long-term hearing preservation after middle fossa removal of vestibular schwannoma. Otolaryngol Head Neck Surg. 2003 Dec; 129(6):660-5. Friedman RA, Kesser B, Brackmann DE, Fisher LM, Slattery WH, Hitselberger WE. PMID: 14663432.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    84. A natural allele of Nxf1 suppresses retrovirus insertional mutations. Nat Genet. 2003 Nov; 35(3):221-8. Floyd JA, Gold DA, Concepcion D, Poon TH, Wang X, Keithley E, Chen D, Ward EJ, Chinn SB, Friedman RA, Yu HT, Moriwaki K, Shiroishi T, Hamilton BA. PMID: 14517553.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    85. Long-term follow-up of arrhythmias in pediatric orthotopic heart transplant recipients: incidence and correlation with rejection. J Heart Lung Transplant. 2003 Aug; 22(8):889-93. Kertesz NJ, Towbin JA, Clunie S, Fenrich AL, Friedman RA, Kearney DL, Dreyer WJ, Price JF, Radovancevic B, Denfield SW. PMID: 12909469.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    86. The emergency department versus the computer: which is the better electrocardiographer? Pediatr Cardiol. 2003 Jul-Aug; 24(4):364-8. Snyder CS, Fenrich AL, Friedman RA, Macias C, O'Reilly K, Kertesz NJ. PMID: 12457259.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    87. Use of intravenous amiodarone for postoperative junctional ectopic tachycardia in children. Pediatr Cardiol. 2003 Mar-Apr; 24(2):133-7. Laird WP, Snyder CS, Kertesz NJ, Friedman RA, Miller D, Fenrich AL. PMID: 12370794.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    88. Nonsyndromic hereditary hearing loss. Otolaryngol Clin North Am. 2002 Apr; 35(2):275-85. Li XC, Friedman RA. PMID: 12391618.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    89. Hearing preservation in patients with vestibular schwannomas with sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 2001 Nov; 125(5):544-51. Friedman RA, Kesser BW, Slattery WH, Brackmann DE, Hitselberger WE. PMID: 11700458.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    90. Congenital complete atrioventricular block. Pacing Clin Electrophysiol. 2001 Nov; 24(11):1681-8. Friedman RA, Fenrich AL, Kertesz NJ. PMID: 11816640.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    91. Early proactive management of vestibular schwannomas in neurofibromatosis type 2. Neurosurgery. 2001 Aug; 49(2):274-80; discussion 280-3. Brackmann DE, Fayad JN, Slattery WH, Friedman RA, Day JD, Hitselberger WE, Owens RM. PMID: 11504103.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    92. Prognostic factors for hearing preservation in vestibular schwannoma surgery. Am J Otol. 2000 May; 21(3):417-24. Brackmann DE, Owens RM, Friedman RA, Hitselberger WE, De la Cruz A, House JW, Nelson RA, Luxford WM, Slattery WH, Fayad JN. PMID: 10821558.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    93. A transgenic insertional inner ear mutation on mouse chromosome 1. Laryngoscope. 2000 Apr; 110(4):489-96. Friedman RA, Adir Y, Crenshaw EB, Ryan AF, Rosenfeld MG. PMID: 10763993.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    94. Profound hearing loss associated with hydrocodone/acetaminophen abuse. Am J Otol. 2000 Mar; 21(2):188-91. Friedman RA, House JW, Luxford WM, Gherini S, Mills D. PMID: 10733182.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    95. The surgical management of Bell's palsy: a review. Am J Otol. 2000 Jan; 21(1):139-44. Friedman RA. PMID: 10651450.
      View in: PubMed   Mentions: 2     Fields:    
    96. Maternally inherited nonsyndromic hearing loss. Am J Med Genet. 1999 Jun 04; 84(4):369-72. Friedman RA, Bykhovskaya Y, Sue CM, DiMauro S, Bradley R, Fallis-Cunningham R, Paradies N, Pensak ML, Smith RJ, Groden J, Li XC, Fischel-Ghodsian N. PMID: 10340654.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    97. Inner ear and kidney anomalies caused by IAP insertion in an intron of the Eya1 gene in a mouse model of BOR syndrome. Hum Mol Genet. 1999 Apr; 8(4):645-53. Johnson KR, Cook SA, Erway LC, Matthews AN, Sanford LP, Paradies NE, Friedman RA. PMID: 10072433.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    98. Trigeminal schwannomas: the role of the neurotologist in multidisciplinary management. Otolaryngol Head Neck Surg. 1999 Mar; 120(3):355-60. Friedman RA, Pensak ML, Osterhaus D, Tew JM, van Loveren HR. PMID: 10064638.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    99. An analysis of a large postlingually deaf family with hereditary non-syndromic profound hearing loss. Acta Otolaryngol. 1999 Mar; 119(2):158-62. Angeli SI, Naranjo C, Friedman RA, Naranjo A, Henríquez O, Fischel-Ghodsian N, Chiossone E. PMID: 10320067.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    100. Auditory-nerve integrity after middle-fossa acoustic-tumor removal. Otolaryngol Head Neck Surg. 1998 Dec; 119(6):588-92. Friedman RA, Brackmann DE, Mills D. PMID: 9852530.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    101. Predictors of response to acute treatment of chronic and double depression with sertraline or imipramine. J Clin Psychiatry. 1998 Dec; 59(12):669-75. Hirschfeld RM, Russell JM, Delgado PL, Fawcett J, Friedman RA, Harrison WM, Koran LM, Miller IW, Thase ME, Howland RH, Connolly MA, Miceli RJ. PMID: 9921701.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    102. Developmental expression of the TGF beta s in the mouse cochlea. Mech Dev. 1998 Dec; 79(1-2):165-8. Paradies NE, Sanford LP, Doetschman T, Friedman RA. PMID: 10349630.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    103. Stent dilation of superior vena cava and innominate vein obstructions permits transvenous pacing lead implantation. Pacing Clin Electrophysiol. 1998 Aug; 21(8):1517-30. Ing FF, Mullins CE, Grifka RG, Nihill MR, Fenrich AL, Collins EL, Friedman RA. PMID: 9725149.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    104. Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss loci on human chromosome 9q and mouse chromosome 19. Gene. 1998 Jul 30; 215(2):461-9. Scott DA, Greinwald JH, Marietta JR, Drury S, Swiderski RE, Viñas A, DeAngelis MM, Carmi R, Ramesh A, Kraft ML, Elbedour K, Skworak AB, Friedman RA, Srikumari Srisailapathy CR, Verhoeven K, Van Gamp G, Lovett M, Deininger PL, Batzer MA, Morton CC, Keats BJ, Smith RJ, Sheffield VC. PMID: 9758550.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    105. Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2. J Biol Chem. 1998 Jul 24; 273(30):18693-6. Kozel PJ, Friedman RA, Erway LC, Yamoah EN, Liu LH, Riddle T, Duffy JJ, Doetschman T, Miller ML, Cardell EL, Shull GE. PMID: 9668038.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    106. Left-sided atrioventricular nodal ablation using the transseptal approach: clinico-histopathologic correlation. J Cardiovasc Electrophysiol. 1998 Jul; 9(7):757-60. Fenrich AL, Friedman RA, Cecchin FC, Kearney D. PMID: 9684723.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    107. The role of endolymphatic mastoid shunt surgery in the managed care era. Am J Otol. 1998 May; 19(3):337-40. Pensak ML, Friedman RA. PMID: 9596185.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    108. Fallopian bridge technique in surgery for chronic ear disease. Laryngoscope. 1997 Nov; 107(11 Pt 1):1451-6. Pensak ML, Friedman RA. PMID: 9369389.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    109. Anterior petrosectomy approach to infraclinoidal basilar artery aneurysms: the emerging role of the neuro-otologist in multidisciplinary management of basilar artery aneurysms. Laryngoscope. 1997 Jul; 107(7):977-83. Friedman RA, Pensak ML, Tauber M, Tew JM, van Loveren HR. PMID: 9217142.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    110. Novel approach to transvenous pacemaker implantation in a post-fontan adolescent. Pediatr Cardiol. 1997 Jul-Aug; 18(4):309-11. Johnsrude CL, Mullins CE, Vincent J, Fagan TE, Friedman RA. PMID: 9175532.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    111. Molecular analysis of the POU3F4 gene in patients with clinical and radiographic evidence of X-linked mixed deafness with perilymphatic gusher. Ann Otol Rhinol Laryngol. 1997 Apr; 106(4):320-5. Friedman RA, Bykhovskaya Y, Tu G, Talbot JM, Wilson DF, Parnes LS, Fischel-Ghodsian N. PMID: 9109724.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    112. Management of the contracted mastoid in the translabyrinthine removal of acoustic neuroma. Arch Otolaryngol Head Neck Surg. 1997 Mar; 123(3):342-4. Friedman RA, Brackmann DE, van Loveren HR, Hitselberger WE. PMID: 9076243.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    113. Identification of a hot spot for microdeletions in patients with X-linked deafness type 3 (DFN3) 900 kb proximal to the DFN3 gene POU3F4. Hum Mol Genet. 1996 Sep; 5(9):1229-35. de Kok YJ, Vossenaar ER, Cremers CW, Dahl N, Laporte J, Hu LJ, Lacombe D, Fischel-Ghodsian N, Friedman RA, Parnes LS, Thorpe P, Bitner-Glindzicz M, Pander HJ, Heilbronner H, Graveline J, den Dunnen JT, Brunner HG, Ropers HH, Cremers FP. PMID: 8872461.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    114. Posterior fossa meningiomas intimately involved with the endolymphatic sac. Am J Otol. 1996 Jul; 17(4):612-6. Friedman RA, Nelson RA, Harris JP. PMID: 8841708.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    115. Nager acrofacial dysostosis: management of a difficult airway. Int J Pediatr Otorhinolaryngol. 1996 Mar; 35(1):69-72. Friedman RA, Wood E, Pransky SM, Seid AB, Kearns DB. PMID: 8882111.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    116. Transgenic insertional mutagenesis. Applications to inner-ear genetics. Arch Otolaryngol Head Neck Surg. 1996 Mar; 122(3):252-7. Friedman RA. PMID: 8607951.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    117. Effect of age and surgical technique on symptomatic arrhythmias after the Fontan procedure. Am J Cardiol. 1995 Aug 15; 76(5):386-91. Cecchin F, Johnsrude CL, Perry JC, Friedman RA. PMID: 7639165.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    118. Retreatment for relapse following desipramine discontinuation in dysthymia. Am J Psychiatry. 1995 Jun; 152(6):926-8. Friedman RA, Mitchell J, Kocsis JH. PMID: 7755126.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    119. Transesophageal echocardiographic detection of atrial thrombi in patients with nonfibrillation atrial tachyarrhythmias and congenital heart disease. J Am Coll Cardiol. 1994 Nov 01; 24(5):1365-70. Feltes TF, Friedman RA. PMID: 7930262.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    120. Persistence of ventricular arrhythmia after resolution of occult myocarditis in children and young adults. J Am Coll Cardiol. 1994 Sep; 24(3):780-3. Friedman RA, Kearney DL, Moak JP, Fenrich AL, Perry JC. PMID: 8077553.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    121. Successful closure of a previously unsuspected atrial septal defect by an implantable Clamshell device and subsequent transvenous pacemaker implantation. Tex Heart Inst J. 1994; 21(2):161-5. Friedman RA, O'Laughlin MP, Moak JP, Perry JC, Mullins CE, Garson A, Feltes TF. PMID: 8061541.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    122. Transgenic mice. Current applications to the study of the auditory and vestibular systems. Otolaryngol Clin North Am. 1992 Oct; 25(5):1017-26. Friedman RA, Ryan AF. PMID: 1408190.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    123. Bradycardia and syncope in children not controlled by pacing: beta-adrenergic hypersensitivity. Pacing Clin Electrophysiol. 1991 Mar; 14(3):391-4. Perry JC, Friedman RA, Moak JP, Garson A. PMID: 1708866.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    124. Sinusitis. Annu Rev Med. 1991; 42:471-89. Friedman RA, Harris JP. PMID: 2035989.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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