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Claude Sirlin

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentRadiology
Address9500 Gilman Drive #0888
La Jolla CA 92093
Phone858-246-2203
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    Collapse Biography 
    Collapse Education and Training
    Havard UniversityB.A.Biology
    University of California, San FranciscoM.D.Medicine
    Collapse Awards and Honors
    Radiological Society of North America1996Research Resident Award
    Radiological Society of North America Research Roentgen 1998  - 1999Research Awards
    Elliot C. Lasser2000Award for Excellence in Research
    Stanford University2001 Radiology Teaching Award
    Society of Gastrointestinal Radiologists 2006Phillip H. Meyers Research Award
    Association of University Radiologists2007Radiology Research Alliance New Investigator Award
    ISMRM2008Outstanding Teacher Award: Case-Based Teaching Series
    UCSF2009Earl Miller Memorial Lecturer
    ESGAR2011SGR Honorary Lecturer

    Collapse Research 
    Collapse Research Activities and Funding
    QUS Technology for Diagnosis and Grading of Hepatic Steatosis in NAFLD
    NIH/NIDDK R01DK106419Jul 1, 2015 - May 31, 2020
    Role: Principal Investigator
    Development of MR-based biomarker panels for NAFLD - A NASH CRN Ancillary Study
    NIH/NIDDK R56DK090350Sep 30, 2010 - Aug 31, 2013
    Role: Principal Investigator
    Technical Validation of MRI Biomarkers of Liver Fat
    NIH/NIDDK R01DK088925Sep 15, 2010 - Jul 31, 2022
    Role: Principal Investigator
    MR Imaging of Non-Alcoholic Fatty Liver Disease
    NIH/NIDDK R01DK075128Sep 1, 2006 - Mar 31, 2012
    Role: Principal Investigator
    Training Clinical Scientists in Radiological Imaging
    NIH/NIBIB T32EB005970Apr 1, 2006 - Jun 30, 2018
    Role: Principal Investigator
    Transducible Molecular Probes for Imaging Tumors
    NIH/NCI K08CA102158Jul 18, 2003 - Jun 30, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Han A, Labyed Y, Sy EZ, Boehringer AS, Andre MP, Erdman JW, Loomba R, Sirlin C, O'Brien WD. Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease. Eur Radiol. 2018 Jun 04. PMID: 29869170.
      View in: PubMed
    2. Zhang Y, Fowler KJ, Hamilton G, Cui J, Sy EZ, Balanay M, Hooker JC, Szeverenyi NM, Sirlin C. Liver fat imaging - a clinical overview of ultrasound, CT, and MR imaging. Br J Radiol. 2018 May 03; 20170959. PMID: 29722568.
      View in: PubMed
    3. Park CC, Hooker C, Hooker JC, Bass E, Haufe W, Schlein A, Covarrubias Y, Heba E, Bydder M, Wolfson T, Gamst A, Loomba R, Schwimmer J, Hernando D, Reeder SB, Middleton M, Sirlin C, Hamilton G. Assessment of a high-SNR chemical-shift-encoded MRI with complex reconstruction for proton density fat fraction (PDFF) estimation overall and in the low-fat range. J Magn Reson Imaging. 2018 Apr 29. PMID: 29707848.
      View in: PubMed
    4. Lawitz EJ, Coste A, Poordad F, Alkhouri N, Loo N, McColgan BJ, Tarrant JM, Nguyen T, Han L, Chung C, Ray AS, McHutchison JG, Subramanian GM, Myers RP, Middleton MS, Sirlin C, Loomba R, Nyangau E, Fitch M, Li K, Hellerstein M. Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients with Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2018 Apr 26. PMID: 29705265.
      View in: PubMed
    5. Chalasani N, Vuppalanchi R, Rinella M, Middleton MS, Siddiqui MS, Barritt AS, Kolterman O, Flores O, Alonso C, Iruarrizaga-Lejarreta M, Gil-Redondo R, Sirlin C, Zemel MB. Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2018 Apr 25. PMID: 29696666.
      View in: PubMed
    6. Ajmera V, Park CC, Caussy C, Singh S, Hernandez C, Bettencourt R, Hooker J, Sy E, Behling C, Xu R, Middleton MS, Valasek MA, Faulkner C, Rizo E, Richards L, Sirlin C, Loomba R. Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 Apr 13. PMID: 29660324.
      View in: PubMed
    7. Kielar AZ, Chernyak V, Bashir MR, Do RK, Fowler KJ, Mitchell DG, Cerny M, Elsayes KM, Santillan C, Kamaya A, Kono Y, Sirlin C, Tang A. LI-RADS 2017: An update. J Magn Reson Imaging. 2018 Jun; 47(6):1459-1474. PMID: 29626376.
      View in: PubMed
    8. Marrero JA, Kulik LM, Sirlin C, Zhu AX, Finn RS, Abecassis MM, Roberts LR, Heimbach JK. Diagnosis, Staging and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018 Apr 06. PMID: 29624699.
      View in: PubMed
    9. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin C, Chen CH, Loomba R. Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2018 Mar 23. PMID: 29572891.
      View in: PubMed
    10. Kennedy P, Wagner M, Castéra L, Hong CW, Johnson CL, Sirlin C, Taouli B. Quantitative Elastography Methods in Liver Disease: Current Evidence and Future Directions. Radiology. 2018 03; 286(3):738-763. PMID: 29461949.
      View in: PubMed
    11. Besa C, Lewis S, Pandharipande PV, Chhatwal J, Kamath A, Cooper N, Knight-Greenfield A, Babb JS, Boffetta P, Padron N, Sirlin C, Taouli B. Erratum to: Hepatocellular carcinoma detection: diagnostic performance of a simulated abbreviated MRI protocol combining diffusion-weighted and T1-weighted imaging at the delayed phase post gadoxetic acid. Abdom Radiol (NY). 2018 Mar; 43(3):760. PMID: 28755071.
      View in: PubMed
    12. Caussy C, Alquiraish MH, Nguyen P, Hernandez C, Cepin S, Fortney LE, Ajmera V, Bettencourt R, Collier S, Hooker J, Sy E, Rizo E, Richards L, Sirlin C, Loomba R. Optimal threshold of controlled attenuation parameter with MRI-PDFF as the gold standard for the detection of hepatic steatosis. Hepatology. 2018 Apr; 67(4):1348-1359. PMID: 29108123.
      View in: PubMed
    13. Dietrich CF, Averkiou M, Nielsen MB, Barr RG, Burns PN, Calliada F, Cantisani V, Choi B, Chammas MC, Clevert DA, Claudon M, Correas JM, Cui XW, Cosgrove D, D'Onofrio M, Dong Y, Eisenbrey J, Fontanilla T, Gilja OH, Ignee A, Jenssen C, Kono Y, Kudo M, Lassau N, Lyshchik A, Franca Meloni M, Moriyasu F, Nolsøe C, Piscaglia F, Radzina M, Saftoiu A, Sidhu PS, Sporea I, Schreiber-Dietrich D, Sirlin C, Stanczak M, Weskott HP, Wilson SR, Willmann JK, Kim TK, Jang HJ, Vezeridis A, Westerway S. How to perform Contrast-Enhanced Ultrasound (CEUS). Ultrasound Int Open. 2018 Jan; 4(1):E2-E15. PMID: 29423461.
      View in: PubMed
    14. Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin C. Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. Hepatology. 2018 Mar; 67(3):858-872. PMID: 29028128.
      View in: PubMed
    15. Brunt E, Aishima S, Clavien PA, Fowler K, Goodman Z, Gores G, Gouw A, Kagen A, Klimstra D, Komuta M, Kondo F, Miksad R, Nakano M, Nakanuma Y, Ng I, Paradis V, Nyun Park Y, Quaglia A, Roncalli M, Roskams T, Sakamoto M, Saxena R, Sempoux C, Sirlin C, Stueck A, Thung S, Tsui WMS, Wang XW, Wee A, Yano H, Yeh M, Zen Y, Zucman-Rossi J, Theise N. cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation. Hepatology. 2018 Jan 23. PMID: 29360137.
      View in: PubMed
    16. Han A, Andre MP, Deiranieh L, Housman E, Erdman JW, Loomba R, Sirlin C, O'Brien WD. Repeatability and Reproducibility of the Ultrasonic Attenuation Coefficient and Backscatter Coefficient Measured in the Right Lobe of the Liver in Adults With Known or Suspected Nonalcoholic Fatty Liver Disease. J Ultrasound Med. 2018 Jan 23. PMID: 29359454.
      View in: PubMed
    17. Caussy C, Reeder SB, Sirlin C, Loomba R. Non-invasive, quantitative assessment of liver fat by MRI-PDFF as an endpoint in NASH trials. Hepatology. 2018 Jan 21. PMID: 29356032.
      View in: PubMed
    18. Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin C, Ehman RL, Loomba R. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. Clin Gastroenterol Hepatol. 2018 Jan 17. PMID: 29104128.
      View in: PubMed
    19. Fowler KJ, Potretzke TA, Hope TA, Costa EA, Wilson SR, Sirlin C, Tang A, Kielar A. Letter to the editor response. Abdom Radiol (NY). 2018 Jan; 43(1):239. PMID: 29167945.
      View in: PubMed
    20. Mitchell DG, Bashir MR, Sirlin C. Management implications and outcomes of LI-RADS-2, -3, -4, and -M category observations. Abdom Radiol (NY). 2018 Jan; 43(1):143-148. PMID: 28779335.
      View in: PubMed
    21. Santillan C, Chernyak V, Sirlin C. LI-RADS categories: concepts, definitions, and criteria. Abdom Radiol (NY). 2018 Jan; 43(1):101-110. PMID: 29038857.
      View in: PubMed
    22. Papadatos D, Fowler KJ, Kielar AZ, Cui J, Sirlin C. Cirrhosis and LI-RADS. Abdom Radiol (NY). 2018 Jan; 43(1):26-40. PMID: 29218367.
      View in: PubMed
    23. Narsinh KH, Cui J, Papadatos D, Sirlin C, Santillan CS. Hepatocarcinogenesis and LI-RADS. Abdom Radiol (NY). 2018 Jan; 43(1):158-168. PMID: 29209739.
      View in: PubMed
    24. Sirlin C. The LI-RADS adventure-a personal statement. Abdom Radiol (NY). 2018 Jan; 43(1):1-2. PMID: 29282489.
      View in: PubMed
    25. Tang A, Fowler KJ, Chernyak V, Chapman WC, Sirlin C. LI-RADS and transplantation for hepatocellular carcinoma. Abdom Radiol (NY). 2018 Jan; 43(1):193-202. PMID: 28612162.
      View in: PubMed
    26. Tang A, Hallouch O, Chernyak V, Kamaya A, Sirlin C. Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis. Abdom Radiol (NY). 2018 Jan; 43(1):13-25. PMID: 28647765.
      View in: PubMed
    27. Heimbach JK, Kulik LM, Finn RS, Sirlin C, Abecassis MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. 2018 01; 67(1):358-380. PMID: 28130846.
      View in: PubMed
    28. Sirlin C, Kielar AZ, Tang A, Bashir MR. LI-RADS: a glimpse into the future. Abdom Radiol (NY). 2018 Jan; 43(1):231-236. PMID: 29318354.
      View in: PubMed
    29. Tang A, Cruite I, Mitchell DG, Sirlin C. Hepatocellular carcinoma imaging systems: why they exist, how they have evolved, and how they differ. Abdom Radiol (NY). 2018 Jan; 43(1):3-12. PMID: 28840293.
      View in: PubMed
    30. Chernyak V, Santillan CS, Papadatos D, Sirlin C. LI-RADS® algorithm: CT and MRI. Abdom Radiol (NY). 2018 Jan; 43(1):111-126. PMID: 28695233.
      View in: PubMed
    31. Wilson SR, Lyshchik A, Piscaglia F, Cosgrove D, Jang HJ, Sirlin C, Dietrich CF, Kim TK, Willmann JK, Kono Y. CEUS LI-RADS: algorithm, implementation, and key differences from CT/MRI. Abdom Radiol (NY). 2018 Jan; 43(1):127-142. PMID: 28819825.
      View in: PubMed
    32. Tillman BG, Gorman JD, Hru JM, Lee MH, King MC, Sirlin C, Marks RM. Diagnostic per-lesion performance of a simulated gadoxetate disodium-enhanced abbreviated MRI protocol for hepatocellular carcinoma screening. Clin Radiol. 2018 May; 73(5):485-493. PMID: 29246586.
      View in: PubMed
    33. Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin C, Jacobsen GR. How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc. 2018 Apr; 32(4):1675-1682. PMID: 29218660.
      View in: PubMed
    34. Fraum TJ, Ludwig DR, Kilian S, Curtis WA, Pilgram TK, Sirlin C, Fowler KJ. Epidemiology of Hepatic Steatosis at a Tertiary Care Center: An MRI-based Analysis. Acad Radiol. 2018 Mar; 25(3):317-327. PMID: 29199057.
      View in: PubMed
    35. Hong CW, Fazeli Dehkordy S, Hooker JC, Hamilton G, Sirlin C. Fat Quantification in the Abdomen. Top Magn Reson Imaging. 2017 Dec; 26(6):221-227. PMID: 29176468.
      View in: PubMed
    36. Wang K, Manning P, Szeverenyi N, Wolfson T, Hamilton G, Middleton MS, Vaida F, Yin M, Glaser K, Ehman RL, Sirlin C. Repeatability and reproducibility of 2D and 3D hepatic MR elastography with rigid and flexible drivers at end-expiration and end-inspiration in healthy volunteers. Abdom Radiol (NY). 2017 Dec; 42(12):2843-2854. PMID: 28612163.
      View in: PubMed
    37. Roberts LR, Sirlin C, Zaiem F, Almasri J, Prokop LJ, Heimbach JK, Murad MH, Mohammed K. Imaging for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis. Hepatology. 2018 01; 67(1):401-421. PMID: 28859233.
      View in: PubMed
    38. Tang A, Bashir MR, Corwin MT, Cruite I, Dietrich CF, Do RKG, Ehman EC, Fowler KJ, Hussain HK, Jha RC, Karam AR, Mamidipalli A, Marks RM, Mitchell DG, Morgan TA, Ohliger MA, Shah A, Vu KN, Sirlin C. Evidence Supporting LI-RADS Major Features for CT- and MR Imaging-based Diagnosis of Hepatocellular Carcinoma: A Systematic Review. Radiology. 2018 Jan; 286(1):29-48. PMID: 29166245.
      View in: PubMed
    39. Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin C. Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. NMR Biomed. 2018 Jan; 31(1). PMID: 29130539.
      View in: PubMed
    40. Elsayes KM, Hooker JC, Agrons MM, Kielar AZ, Tang A, Fowler KJ, Chernyak V, Bashir MR, Kono Y, Do RK, Mitchell DG, Kamaya A, Hecht EM, Sirlin C. 2017 Version of LI-RADS for CT and MR Imaging: An Update. Radiographics. 2017 Nov-Dec; 37(7):1994-2017. PMID: 29131761.
      View in: PubMed
    41. Fetzer DT, Rodgers SK, Harris AC, Kono Y, Wasnik AP, Kamaya A, Sirlin C. Screening and Surveillance of Hepatocellular Carcinoma: An Introduction to Ultrasound Liver Imaging Reporting and Data System. Radiol Clin North Am. 2017 Nov; 55(6):1197-1209. PMID: 28991560.
      View in: PubMed
    42. Fowler KJ, Tang A, Santillan C, Bhargavan-Chatfield M, Heiken J, Jha RC, Weinreb J, Hussain H, Mitchell DG, Bashir MR, Costa EAC, Cunha GM, Coombs L, Wolfson T, Gamst AC, Brancatelli G, Yeh B, Sirlin C. Interreader Reliability of LI-RADS Version 2014 Algorithm and Imaging Features for Diagnosis of Hepatocellular Carcinoma: A Large International Multireader Study. Radiology. 2018 01; 286(1):173-185. PMID: 29091751.
      View in: PubMed
    43. Fazeli Dehkordy S, Fowler KJ, Wolfson T, Igarashi S, Lamas Constantino CP, Hooker JC, Hong CW, Mamidipalli A, Gamst AC, Hemming A, Sirlin C. Technical report: gadoxetate-disodium-enhanced 2D R2* mapping: a novel approach for assessing bile ducts in living donors. Abdom Radiol (NY). 2017 Oct 31. PMID: 29086007.
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    44. Brouha SS, Nguyen P, Bettencourt R, Sirlin C, Loomba R. Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. Eur Radiol. 2018 Apr; 28(4):1345-1355. PMID: 29058029.
      View in: PubMed
    45. Corwin MT, Lee AY, Fananapazir G, Loehfelm TW, Sarkar S, Sirlin C. Nonstandardized Terminology to Describe Focal Liver Lesions in Patients at Risk for Hepatocellular Carcinoma: Implications Regarding Clinical Communication. AJR Am J Roentgenol. 2018 Jan; 210(1):85-90. PMID: 29023148.
      View in: PubMed
    46. Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin C. Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. Hepatology. 2017 11; 66(5):1474-1485. PMID: 28493388.
      View in: PubMed
    47. Kim TK, Noh SY, Wilson SR, Kono Y, Piscaglia F, Jang HJ, Lyshchik A, Dietrich CF, Willmann JK, Vezeridis A, Sirlin C. Contrast-enhanced ultrasound (CEUS) liver imaging reporting and data system (LI-RADS) 2017 - a review of important differences compared to the CT/MRI system. Clin Mol Hepatol. 2017 Dec; 23(4):280-289. PMID: 28911220.
      View in: PubMed
    48. Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn JP, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB, Sirlin C. Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis. Radiology. 2018 02; 286(2):486-498. PMID: 28892458.
      View in: PubMed
    49. Hong CW, Mamidipalli A, Hooker JC, Hamilton G, Wolfson T, Chen DH, Fazeli Dehkordy S, Middleton MS, Reeder SB, Loomba R, Sirlin C. MRI proton density fat fraction is robust across the biologically plausible range of triglyceride spectra in adults with nonalcoholic steatohepatitis. J Magn Reson Imaging. 2018 Apr; 47(4):995-1002. PMID: 28851124.
      View in: PubMed
    50. Hong CW, Wolfson T, Sy EZ, Schlein AN, Hooker JC, Fazeli Dehkordy S, Hamilton G, Reeder SB, Loomba R, Sirlin C. Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. J Magn Reson Imaging. 2018 Apr; 47(4):988-994. PMID: 28842937.
      View in: PubMed
    51. Chernyak V, Kobi M, Flusberg M, Fruitman KC, Sirlin C. Effect of threshold growth as a major feature on LI-RADS categorization. Abdom Radiol (NY). 2017 Aug; 42(8):2089-2100. PMID: 28352950.
      View in: PubMed
    52. Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, Hemming A, Andrews B, Salotti J, Richards L, Brenner DA, Sirlin C, Loomba R. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. J Clin Invest. 2017 Jun 30; 127(7):2697-2704. PMID: 28628033.
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    53. Middleton MS, Heba ER, Hooker CA, Bashir MR, Fowler KJ, Sandrasegaran K, Brunt EM, Kleiner DE, Doo E, Van Natta ML, Lavine JE, Neuschwander-Tetri BA, Sanyal A, Loomba R, Sirlin C. Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. Gastroenterology. 2017 09; 153(3):753-761. PMID: 28624576.
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    54. Sirlin C. Use of the Liver Imaging Reporting and Data System in Hepatocellular Carcinoma. Gastroenterol Hepatol (N Y). 2017 Jun; 13(6):363-365. PMID: 28690453.
      View in: PubMed
    55. Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin C. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 Feb; 47(2):418-424. PMID: 28543915.
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    56. Serai SD, Obuchowski NA, Venkatesh SK, Sirlin C, Miller FH, Ashton E, Cole PE, Ehman RL. Repeatability of MR Elastography of Liver: A Meta-Analysis. Radiology. 2017 10; 285(1):92-100. PMID: 28530847.
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    57. Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin C, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5. PMID: 28467925.
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    58. Park CC, Hamilton G, Desai A, Zand KA, Wolfson T, Hooker JC, Costa E, Heba E, Clark L, Gamst A, Loomba R, Middleton MS, Sirlin C. Effect of intravenous gadoxetate disodium and flip angle on hepatic proton density fat fraction estimation with six-echo, gradient-recalled-echo, magnitude-based MR imaging at 3T. Abdom Radiol (NY). 2017 Apr; 42(4):1189-1198. PMID: 28028556.
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    59. Piscaglia F, Wilson SR, Lyshchik A, Cosgrove D, Dietrich CF, Jang HJ, Kim TK, Salvatore V, Willmann JK, Sirlin C, Kono Y. American College of Radiology Contrast Enhanced Ultrasound Liver Imaging Reporting and Data System (CEUS LI-RADS) for the diagnosis of Hepatocellular Carcinoma: a pictorial essay. Ultraschall Med. 2017 Jun; 38(3):320-324. PMID: 28329875.
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    60. Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB, Sirlin C. Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. J Magn Reson Imaging. 2017 Dec; 46(6):1641-1647. PMID: 28323377.
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    61. Middleton MS, Haufe W, Hooker J, Borga M, Dahlqvist Leinhard O, Romu T, Tunón P, Hamilton G, Wolfson T, Gamst A, Loomba R, Sirlin C. Quantifying Abdominal Adipose Tissue and Thigh Muscle Volume and Hepatic Proton Density Fat Fraction: Repeatability and Accuracy of an MR Imaging-based, Semiautomated Analysis Method. Radiology. 2017 05; 283(2):438-449. PMID: 28278002.
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    62. Paige JS, Bernstein GS, Heba E, Costa EAC, Fereirra M, Wolfson T, Gamst AC, Valasek MA, Lin GY, Han A, Erdman JW, O'Brien WD, Andre MP, Loomba R, Sirlin C. A Pilot Comparative Study of Quantitative Ultrasound, Conventional Ultrasound, and MRI for Predicting Histology-Determined Steatosis Grade in Adult Nonalcoholic Fatty Liver Disease. AJR Am J Roentgenol. 2017 May; 208(5):W168-W177. PMID: 28267360.
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    63. Manning PM, Hamilton G, Wang K, Park C, Hooker JC, Wolfson T, Gamst A, Haufe WM, Schlein AN, Middleton MS, Sirlin C. Agreement between region-of-interest- and parametric map-based hepatic proton density fat fraction estimation in adults with chronic liver disease. Abdom Radiol (NY). 2017 Mar; 42(3):833-841. PMID: 27688063.
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    64. Kono Y, Lyshchik A, Cosgrove D, Dietrich CF, Jang HJ, Kim TK, Piscaglia F, Willmann JK, Wilson SR, Santillan C, Kambadakone A, Mitchell D, Vezeridis A, Sirlin C. Contrast Enhanced Ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS®): the official version by the American College of Radiology (ACR). Ultraschall Med. 2017 Jan; 38(1):85-86. PMID: 28249328.
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    65. Manning P, Murphy P, Wang K, Hooker J, Wolfson T, Middleton MS, Newton KP, Behling C, Awai HI, Durelle J, Paiz MN, Angeles JE, De La Pena D, McCutchan JA, Schwimmer JB, Sirlin C. Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study. J Magn Reson Imaging. 2017 Oct; 46(4):1149-1158. PMID: 28225568.
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    66. Elsayes KM, Kielar AZ, Agrons MM, Szklaruk J, Tang A, Bashir MR, Mitchell DG, Do RK, Fowler KJ, Chernyak V, Sirlin C. Liver Imaging Reporting and Data System: an expert consensus statement. J Hepatocell Carcinoma. 2017; 4:29-39. PMID: 28255543.
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    67. Lin SC, Heba E, Bettencourt R, Lin GY, Valasek MA, Lunde O, Hamilton G, Sirlin C, Loomba R. Assessment of treatment response in non-alcoholic steatohepatitis using advanced magnetic resonance imaging. Aliment Pharmacol Ther. 2017 03; 45(6):844-854. PMID: 28116801.
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    68. Hoogi A, Beaulieu CF, Cunha GM, Heba E, Sirlin C, Napel S, Rubin DL. Adaptive local window for level set segmentation of CT and MRI liver lesions. Med Image Anal. 2017 Apr; 37:46-55. PMID: 28157660.
      View in: PubMed
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    146. Liau J, Shiehmorteza M, Girard OM, Sirlin C, Bydder M. Evaluation of MRI fat fraction in the liver and spine pre and post SPIO infusion. Magn Reson Imaging. 2013 Jul; 31(6):1012-6. PMID: 23602721; PMCID: PMC3676690.
    147. Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin C. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7. PMID: 23596052; PMCID: PMC3732566.
    148. Tang A, Cruite I, Sirlin C. Toward a standardized system for hepatocellular carcinoma diagnosis using computed tomography and MRI. Expert Rev Gastroenterol Hepatol. 2013 Mar; 7(3):269-79. PMID: 23445236.
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    149. Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin C. Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31. PMID: 23382291; PMCID: PMC3632805.
    150. Murphy P, Wolfson T, Gamst A, Sirlin C, Bydder M. Error model for reduction of cardiac and respiratory motion effects in quantitative liver DW-MRI. Magn Reson Med. 2013 Nov; 70(5):1460-9. PMID: 23280855; PMCID: PMC4142067.
    151. Mashhood A, Railkar R, Yokoo T, Levin Y, Clark L, Fox-Bosetti S, Middleton MS, Riek J, Kauh E, Dardzinski BJ, Williams D, Sirlin C, Shire NJ. Reproducibility of hepatic fat fraction measurement by magnetic resonance imaging. J Magn Reson Imaging. 2013 Jun; 37(6):1359-70. PMID: 23172799.
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    152. Sirlin C. Invited commentary. Radiographics. 2012 Nov-Dec; 32(7):1995-8; discussion 1998. PMID: 23304704.
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    153. Vidimar V, Meng X, Klajner M, Licona C, Fetzer L, Harlepp S, Hébraud P, Sidhoum M, Sirlin C, Loeffler JP, Mellitzer G, Sava G, Pfeffer M, Gaiddon C. Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity. Biochem Pharmacol. 2012 Dec 01; 84(11):1428-36. PMID: 22964219.
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    154. Bahl G, Cruite I, Wolfson T, Gamst AC, Collins JM, Chavez AD, Barakat F, Hassanein T, Sirlin C. Noninvasive classification of hepatic fibrosis based on texture parameters from double contrast-enhanced magnetic resonance images. J Magn Reson Imaging. 2012 Nov; 36(5):1154-61. PMID: 22851409; PMCID: PMC4803477.
    155. Reeder SB, Hu HH, Sirlin C. Proton density fat-fraction: a standardized MR-based biomarker of tissue fat concentration. J Magn Reson Imaging. 2012 Nov; 36(5):1011-4. PMID: 22777847; PMCID: PMC4779595.
    156. Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology. 2012 Sep; 56(3):922-32. PMID: 22431131; PMCID: PMC3400720.
    157. Campos JT, Sirlin C, Choi JY. Focal hepatic lesions in Gd-EOB-DTPA enhanced MRI: the atlas. Insights Imaging. 2012 Oct; 3(5):451-74. PMID: 22700119; PMCID: PMC3443279.
    158. Hu HH, Börnert P, Hernando D, Kellman P, Ma J, Reeder S, Sirlin C. ISMRM workshop on fat-water separation: insights, applications and progress in MRI. Magn Reson Med. 2012 Aug; 68(2):378-88. PMID: 22693111; PMCID: PMC3575097.
    159. Kang BK, Yu ES, Lee SS, Lee Y, Kim N, Sirlin C, Cho EY, Yeom SK, Byun JH, Park SH, Lee MG. Hepatic fat quantification: a prospective comparison of magnetic resonance spectroscopy and analysis methods for chemical-shift gradient echo magnetic resonance imaging with histologic assessment as the reference standard. Invest Radiol. 2012 Jun; 47(6):368-75. PMID: 22543969.
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    160. Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor d agonist. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):E1369-76. PMID: 22538808; PMCID: PMC3361396.
    161. Lee JT, Liau J, Murphy P, Schroeder ME, Sirlin C, Bydder M. Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging. Magn Reson Imaging. 2012 May; 30(4):572-8. PMID: 22285877; PMCID: PMC3327769.
    162. Hansen KH, Schroeder ME, Hamilton G, Sirlin C, Bydder M. Robustness of fat quantification using chemical shift imaging. Magn Reson Imaging. 2012 Feb; 30(2):151-7. PMID: 22055856; PMCID: PMC3254829.
    163. Reeder SB, Cruite I, Hamilton G, Sirlin C. Quantitative Assessment of Liver Fat with Magnetic Resonance Imaging and Spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):spcone. PMID: 22025886.
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    164. Reeder SB, Cruite I, Hamilton G, Sirlin C. Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):729-49. PMID: 21928307.
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    165. Goodwin MD, Dobson JE, Sirlin C, Lim BG, Stella DL. Diagnostic challenges and pitfalls in MR imaging with hepatocyte-specific contrast agents. Radiographics. 2011 Oct; 31(6):1547-68. PMID: 21997981.
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    166. Liau J, Lee J, Schroeder ME, Sirlin C, Bydder M. Cardiac motion in diffusion-weighted MRI of the liver: artifact and a method of correction. J Magn Reson Imaging. 2012 Feb; 35(2):318-27. PMID: 21959926; PMCID: PMC3252483.
    167. Fetzer L, Boff B, Ali M, Xiangjun M, Collin JP, Sirlin C, Gaiddon C, Pfeffer M. Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: passing the nanomolar barrier. Dalton Trans. 2011 Sep 21; 40(35):8869-78. PMID: 21837342.
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    168. Kang GH, Cruite I, Shiehmorteza M, Wolfson T, Gamst AC, Hamilton G, Bydder M, Middleton MS, Sirlin C. Reproducibility of MRI-determined proton density fat fraction across two different MR scanner platforms. J Magn Reson Imaging. 2011 Oct; 34(4):928-34. PMID: 21769986; PMCID: PMC4803481.
    169. Sirlin C. Science to practice: Can T1rho imaging be used to diagnose and assess the severity of hepatic fibrosis? Radiology. 2011 Jun; 259(3):619-20. PMID: 21602499.
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    170. Rajaraman S, Rodriguez JJ, Graff C, Altbach MI, Dragovich T, Sirlin C, Korn RL, Raghunand N. Automated registration of sequential breath-hold dynamic contrast-enhanced MR images: a comparison of three techniques. Magn Reson Imaging. 2011 Jun; 29(5):668-82. PMID: 21531108; PMCID: PMC3100446.
    171. Hines CD, Frydrychowicz A, Hamilton G, Tudorascu DL, Vigen KK, Yu H, McKenzie CA, Sirlin C, Brittain JH, Reeder SB. T(1) independent, T(2) (*) corrected chemical shift based fat-water separation with multi-peak fat spectral modeling is an accurate and precise measure of hepatic steatosis. J Magn Reson Imaging. 2011 Apr; 33(4):873-81. PMID: 21448952; PMCID: PMC3130738.
    172. Yu H, Shimakawa A, Hines CD, McKenzie CA, Hamilton G, Sirlin C, Brittain JH, Reeder SB. Combination of complex-based and magnitude-based multiecho water-fat separation for accurate quantification of fat-fraction. Magn Reson Med. 2011 Jul; 66(1):199-206. PMID: 21695724; PMCID: PMC3130743.
    173. Barshop NJ, Capparelli EV, Sirlin C, Schwimmer JB, Lavine JE. Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):198-202. PMID: 21240014; PMCID: PMC3059772.
    174. Meisamy S, Hines CD, Hamilton G, Sirlin C, McKenzie CA, Yu H, Brittain JH, Reeder SB. Quantification of hepatic steatosis with T1-independent, T2-corrected MR imaging with spectral modeling of fat: blinded comparison with MR spectroscopy. Radiology. 2011 Mar; 258(3):767-75. PMID: 21248233; PMCID: PMC3042638.
    175. Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin C. Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology. 2011 Mar; 258(3):749-59. PMID: 21212366; PMCID: PMC3042639.
    176. Bydder M, Yokoo T, Yu H, Carl M, Reeder SB, Sirlin C. Constraining the initial phase in water-fat separation. Magn Reson Imaging. 2011 Feb; 29(2):216-21. PMID: 21159457; PMCID: PMC3053064.
    177. Hamilton G, Yokoo T, Bydder M, Cruite I, Schroeder ME, Sirlin C, Middleton MS. In vivo characterization of the liver fat ¹H MR spectrum. NMR Biomed. 2011 Aug; 24(7):784-90. PMID: 21834002; PMCID: PMC3860876.
    178. Klajner M, Hebraud P, Sirlin C, Gaiddon C, Harlepp S. DNA binding to an anticancer organo-ruthenium complex. J Phys Chem B. 2010 Nov 11; 114(44):14041-7. PMID: 20961087.
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    179. Karçaaltincaba M, Sirlin C. CT and MRI of diffuse lobar involvement pattern in liver pathology. Diagn Interv Radiol. 2011 Dec; 17(4):334-42. PMID: 21053176.
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    180. Dieng PS, Sirlin C. Recognition of chiral carboxylic anions by artificial receptors. Int J Mol Sci. 2010 Sep 15; 11(9):3334-48. PMID: 20957098; PMCID: PMC2956098.
    181. Sirlin C, Reeder SB. Magnetic resonance imaging quantification of liver iron. Magn Reson Imaging Clin N Am. 2010 Aug; 18(3):359-81, ix. PMID: 21094445; PMCID: PMC3430384.
    182. Reeder SB, Sirlin C. Quantification of liver fat with magnetic resonance imaging. Magn Reson Imaging Clin N Am. 2010 Aug; 18(3):337-57, ix. PMID: 21094444; PMCID: PMC3002753.
    183. Ganesan K, Achmad E, Sirlin C, Bouvet M, Datnow B, Weidner N, Peterson MR. Amphicrine carcinoma of the liver. Ann Diagn Pathol. 2011 Oct; 15(5):355-7. PMID: 20952282.
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    184. Cruite I, Schroeder M, Merkle EM, Sirlin C. Gadoxetate disodium-enhanced MRI of the liver: part 2, protocol optimization and lesion appearance in the cirrhotic liver. AJR Am J Roentgenol. 2010 Jul; 195(1):29-41. PMID: 20566795.
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    185. Ringe KI, Husarik DB, Sirlin C, Merkle EM. Gadoxetate disodium-enhanced MRI of the liver: part 1, protocol optimization and lesion appearance in the noncirrhotic liver. AJR Am J Roentgenol. 2010 Jul; 195(1):13-28. PMID: 20566794.
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    186. Mwangi I, Hanna RF, Kased N, Malek P, Shiehmorteza M, Wolfson T, Gamst A, Sirlin C. Apparent diffusion coefficient of fibrosis and regenerative nodules in the cirrhotic liver at MRI. AJR Am J Roentgenol. 2010 Jun; 194(6):1515-22. PMID: 20489091.
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    187. Yokoo T, Bae WC, Hamilton G, Karimi A, Borgstede JP, Bowen BC, Sirlin C, Chung CB, Crues JV, Bradley WG, Bydder GM. A quantitative approach to sequence and image weighting. J Comput Assist Tomogr. 2010 May-Jun; 34(3):317-31. PMID: 20498530.
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    188. Bydder M, Shiehmorteza M, Yokoo T, Sugay S, Middleton MS, Girard O, Schroeder ME, Wolfson T, Gamst A, Sirlin C. Assessment of liver fat quantification in the presence of iron. Magn Reson Imaging. 2010 Jul; 28(6):767-76. PMID: 20409663; PMCID: PMC2924146.
    189. Schwimmer JB, Dunn W, Norman GJ, Pardee PE, Middleton MS, Kerkar N, Sirlin C. SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology. 2010 Apr; 138(4):1357-64, 1364.e1-2. PMID: 20064512; PMCID: PMC2846968.
    190. Lindbäck SM, Gabbert C, Johnson BL, Smorodinsky E, Sirlin C, Garcia N, Pardee PE, Kistler KD, Schwimmer JB. Pediatric nonalcoholic fatty liver disease: a comprehensive review. Adv Pediatr. 2010; 57(1):85-140. PMID: 21056736.
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    191. Mazhar SM, Shiehmorteza M, Kohl CA, Middleton MS, Sirlin C. Nephrogenic systemic fibrosis in liver disease: a systematic review. J Magn Reson Imaging. 2009 Dec; 30(6):1313-22. PMID: 19937937; PMCID: PMC2844250.
    192. Sirlin C. Noninvasive imaging biomarkers for steatosis assessment. Liver Transpl. 2009 Nov; 15(11):1389-91. PMID: 19877212.
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    193. Faria SC, Ganesan K, Mwangi I, Shiehmorteza M, Viamonte B, Mazhar S, Peterson M, Kono Y, Santillan C, Casola G, Sirlin C. MR imaging of liver fibrosis: current state of the art. Radiographics. 2009 Oct; 29(6):1615-35. PMID: 19959511.
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    194. Loomba R, Sirlin C, Schwimmer JB, Lavine JE. Advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2009 Oct; 50(4):1282-93. PMID: 19637286; PMCID: PMC2757471.
    195. Hyder JA, Allison MA, Barrett-Connor E, Detrano R, Wong ND, Sirlin C, Gapstur SM, Ouyang P, Carr JJ, Criqui MH. Bone mineral density and atherosclerosis: the Multi-Ethnic Study of Atherosclerosis, Abdominal Aortic Calcium Study. Atherosclerosis. 2010 Mar; 209(1):283-9. PMID: 19819456.
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    196. Shiehmorteza M, Sirlin C, Wolfson T, Gamst A, Soumekh AE, Heaton SP, Kohl CA, Pinto N, Bydder M. Effect of shot number on the calculated apparent diffusion coefficient in phantoms and in human liver in diffusion-weighted echo-planar imaging. J Magn Reson Imaging. 2009 Sep; 30(3):547-53. PMID: 19711409.
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    197. Sirlin C. Invited commentary. Radiographics. 2009 Sep-Oct; 29(5):1277-80. PMID: 19764109.
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    198. Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin C. Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging. 2009 Jul; 30(1):145-52. PMID: 19557733; PMCID: PMC2982807.
    199. Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP. Cancer Res. 2009 Jul 01; 69(13):5458-66. PMID: 19549908.
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    200. Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin C. Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology. 2009 Apr; 251(1):67-76. PMID: 19221054; PMCID: PMC2663579.
    201. Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin C. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 2009 May; 136(5):1585-92. PMID: 19208353; PMCID: PMC3397140.
    202. Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin C. Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics. 2009 Jan-Feb; 29(1):231-60. PMID: 19168847.
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    203. Hyder JA, Allison MA, Wong N, Papa A, Lang TF, Sirlin C, Gapstur SM, Ouyang P, Carr JJ, Criqui MH. Association of coronary artery and aortic calcium with lumbar bone density: the MESA Abdominal Aortic Calcium Study. Am J Epidemiol. 2009 Jan 15; 169(2):186-94. PMID: 19064643.
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    204. Mazhar SM, Shiehmorteza M, Sirlin C. Noninvasive assessment of hepatic steatosis. Clin Gastroenterol Hepatol. 2009 Feb; 7(2):135-40. PMID: 19118644.
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    205. Kohl CA, Sirlin C, Peterson MR. A new liver explant fixation technique. Arch Pathol Lab Med. 2008 Dec; 132(12):1859-60. PMID: 19061279.
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    206. Yokoo T, Collins JM, Hanna RF, Bydder M, Middleton MS, Sirlin C. Effects of intravenous gadolinium administration and flip angle on the assessment of liver fat signal fraction with opposed-phase and in-phase imaging. J Magn Reson Imaging. 2008 Jul; 28(1):246-51. PMID: 18581393.
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    207. Bydder M, Hamilton G, Yokoo T, Sirlin C. Optimal phased-array combination for spectroscopy. Magn Reson Imaging. 2008 Jul; 26(6):847-50. PMID: 18486392; PMCID: PMC2868913.
    208. Hanna RF, Aguirre DA, Kased N, Emery SC, Peterson MR, Sirlin C. Cirrhosis-associated hepatocellular nodules: correlation of histopathologic and MR imaging features. Radiographics. 2008 May-Jun; 28(3):747-69. PMID: 18480482.
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    209. Barshop NJ, Sirlin C, Schwimmer JB, Lavine JE. Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2008 Jul; 28(1):13-24. PMID: 18397387.
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    210. Yeh BM, Joe BN, Sirlin C, Webb EM, Westphalen AC, Qayyum A, Coakley FV. Vascular contact with soft tissue: a sign of mesenteric masses at computed tomography. J Comput Assist Tomogr. 2008 Mar-Apr; 32(2):185-90. PMID: 18379299; PMCID: PMC2724062.
    211. Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin C. Relaxation effects in the quantification of fat using gradient echo imaging. Magn Reson Imaging. 2008 Apr; 26(3):347-59. PMID: 18093781; PMCID: PMC2386876.
    212. Hughes-Cassidy F, Wong J, Aguirre D, Chavez AD, Wolfson T, Gamst A, Sirlin C. Transient homogeneously enhancing hepatic masses: can size predict benignity? AJR Am J Roentgenol. 2008 Feb; 190(2):300-7. PMID: 18212213.
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    213. Hanna RF, Kased N, Kwan SW, Gamst AC, Santosa AC, Hassanein T, Sirlin C. Double-contrast MRI for accurate staging of hepatocellular carcinoma in patients with cirrhosis. AJR Am J Roentgenol. 2008 Jan; 190(1):47-57. PMID: 18094293.
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    214. Leite NP, Kased N, Hanna RF, Brown MA, Pereira JM, Cunha R, Sirlin C. Cross-sectional imaging of extranodal involvement in abdominopelvic lymphoproliferative malignancies. Radiographics. 2007 Nov-Dec; 27(6):1613-34. PMID: 18025507.
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    215. Hughes-Cassidy F, Chavez AD, Schlang A, Hassanein T, Gamst A, Wolfson T, Sirlin C. Superparamagnetic iron oxides and low molecular weight gadolinium chelates are synergistic for direct visualization of advanced liver fibrosis. J Magn Reson Imaging. 2007 Sep; 26(3):728-37. PMID: 17685418.
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    216. Kuo MD, Gollub J, Sirlin C, Ooi C, Chen X. Radiogenomic analysis to identify imaging phenotypes associated with drug response gene expression programs in hepatocellular carcinoma. J Vasc Interv Radiol. 2007 Jul; 18(7):821-31. PMID: 17609439.
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    217. Segal E, Sirlin C, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nat Biotechnol. 2007 Jun; 25(6):675-80. PMID: 17515910.
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    218. Hamer OW, Schlottmann K, Sirlin C, Feuerbach S. Technology insight: advances in liver imaging. Nat Clin Pract Gastroenterol Hepatol. 2007 Apr; 4(4):215-28. PMID: 17404589.
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    219. Tamburrini S, Brunetti A, Brown M, Sirlin C, Casola G. Acute appendicitis: diagnostic value of nonenhanced CT with selective use of contrast in routine clinical settings. Eur Radiol. 2007 Aug; 17(8):2055-61. PMID: 17180324.
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    220. Hamer OW, Aguirre DA, Casola G, Lavine JE, Woenckhaus M, Sirlin C. Fatty liver: imaging patterns and pitfalls. Radiographics. 2006 Nov-Dec; 26(6):1637-53. PMID: 17102041.
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    221. Hall FM, Casola G, Sirlin C, Furtado CD, Aguirre DA, Brown MA. Callback and follow-up guidelines for whole-body CT screening. Radiology. 2006 Nov; 241(2):627-8; author reply 628-9. PMID: 17057082.
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    222. Gandhi SN, Brown MA, Wong JG, Aguirre DA, Sirlin C. MR contrast agents for liver imaging: what, when, how. Radiographics. 2006 Nov-Dec; 26(6):1621-36. PMID: 17102040.
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    223. Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE. Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):413-27. PMID: 17033514.
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    224. Aguirre DA, Behling CA, Alpert E, Hassanein TI, Sirlin C. Liver fibrosis: noninvasive diagnosis with double contrast material-enhanced MR imaging. Radiology. 2006 May; 239(2):425-37. PMID: 16641352.
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    225. Brown MA, Mattrey RF, Stamato S, Sirlin C. MRI of the female pelvis using vaginal gel. AJR Am J Roentgenol. 2005 Nov; 185(5):1221-7. PMID: 16247138.
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    226. Aguirre DA, Santosa AC, Casola G, Sirlin C. Abdominal wall hernias: imaging features, complications, and diagnostic pitfalls at multi-detector row CT. Radiographics. 2005 Nov-Dec; 25(6):1501-20. PMID: 16284131.
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    227. Yoo RY, Sirlin C, Gottschalk M, Chang RJ. Ovarian imaging by magnetic resonance in obese adolescent girls with polycystic ovary syndrome: a pilot study. Fertil Steril. 2005 Oct; 84(4):985-95. PMID: 16213854.
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    228. Hamer OW, Sirlin C, Strotzer M, Borisch I, Zorger N, Feuerbach S, Völk M. Chest radiography with a flat-panel detector: image quality with dose reduction after copper filtration. Radiology. 2005 Nov; 237(2):691-700. PMID: 16192324.
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    229. Furtado CD, Aguirre DA, Sirlin C, Dang D, Stamato SK, Lee P, Sani F, Brown MA, Levin DL, Casola G. Whole-body CT screening: spectrum of findings and recommendations in 1192 patients. Radiology. 2005 Nov; 237(2):385-94. PMID: 16170016.
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    230. Hamer OW, Aguirre DA, Casola G, Sirlin C. Imaging features of perivascular fatty infiltration of the liver: initial observations. Radiology. 2005 Oct; 237(1):159-69. PMID: 16100085.
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    231. Pinto Leite N, Pereira JM, Cunha R, Pinto P, Sirlin C. CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings. AJR Am J Roentgenol. 2005 Aug; 185(2):406-17. PMID: 16037513.
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    232. Tamburrini S, Brunetti A, Brown M, Sirlin C, Casola G. CT appearance of the normal appendix in adults. Eur Radiol. 2005 Oct; 15(10):2096-103. PMID: 15912331.
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    233. Brown MA, Sirlin C. Female pelvis. Magn Reson Imaging Clin N Am. 2005 May; 13(2):381-95. PMID: 15935318.
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    234. Sortais JB, Ritleng V, Voelklin A, Holuigue A, Smail H, Barloy L, Sirlin C, Verzijl GK, Boogers JA, de Vries AH, de Vries JG, Pfeffer M. Cycloruthenated primary and secondary amines as efficient catalyst precursors for asymmetric transfer hydrogenation. Org Lett. 2005 Mar 31; 7(7):1247-50. PMID: 15787478.
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    235. Farahmand N, Sirlin C, Brown MA, Shragg GP, Fortlage D, Hoyt DB, Casola G. Hypotensive patients with blunt abdominal trauma: performance of screening US. Radiology. 2005 May; 235(2):436-43. PMID: 15798158.
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    236. Ryabov AD, Le Lagadec R, Estevez H, Toscano RA, Hernandez S, Alexandrova L, Kurova VS, Fischer A, Sirlin C, Pfeffer M. Synthesis, characterization, and electrochemistry of biorelevant photosensitive low-potential orthometalated ruthenium complexes. Inorg Chem. 2005 Mar 07; 44(5):1626-34. PMID: 15733006.
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    237. Laufik M, Buono D, Casola G, Sirlin C. Delayed traumatic bladder rupture. AJR Am J Roentgenol. 2005 Mar; 184(3 Suppl):S99-S101. PMID: 15728038.
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    238. Brown MA, Sirlin C, Farahmand N, Hoyt DB, Casola G. Screening sonography in pregnant patients with blunt abdominal trauma. J Ultrasound Med. 2005 Feb; 24(2):175-81; quiz 183-184. PMID: 15661948.
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    239. Pereira JM, Sirlin C, Pinto PS, Casola G. CT and MR imaging of extrahepatic fatty masses of the abdomen and pelvis: techniques, diagnosis, differential diagnosis, and pitfalls. Radiographics. 2005 Jan-Feb; 25(1):69-85. PMID: 15653588.
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    240. Sirlin C, Vera DR, Corbeil JA, Caballero MB, Buxton RB, Mattrey RF. Gadolinium-DTPA-dextran: a macromolecular MR blood pool contrast agent. Acad Radiol. 2004 Dec; 11(12):1361-9. PMID: 15596374.
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    241. Aguirre DA, Casola G, Sirlin C. Abdominal wall hernias: MDCT findings. AJR Am J Roentgenol. 2004 Sep; 183(3):681-90. PMID: 15333356.
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    242. Pereira JM, Sirlin C, Pinto PS, Jeffrey RB, Stella DL, Casola G. Disproportionate fat stranding: a helpful CT sign in patients with acute abdominal pain. Radiographics. 2004 May-Jun; 24(3):703-15. PMID: 15143223.
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    243. Pinto PS, Sirlin C, Andrade-Barreto OA, Brown MA, Mindelzun RE, Mattrey RF. Cisterna chyli at routine abdominal MR imaging: a normal anatomic structure in the retrocrural space. Radiographics. 2004 May-Jun; 24(3):809-17. PMID: 15143230.
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    244. Sirlin C, Brown MA, Andrade-Barreto OA, Deutsch R, Fortlage DA, Hoyt DB, Casola G. Blunt abdominal trauma: clinical value of negative screening US scans. Radiology. 2004 Mar; 230(3):661-8. PMID: 14990832.
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    245. Kono Y, Pinnell SP, Sirlin C, Sparks SR, Georgy B, Wong W, Mattrey RF. Carotid arteries: contrast-enhanced US angiography--preliminary clinical experience. Radiology. 2004 Feb; 230(2):561-8. PMID: 14699188.
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    246. Sirlin C, Brown MA, Deutsch R, Andrade-Barreto OA, Fortlage DA, Hoyt DB, Casola G. Screening US for blunt abdominal trauma: objective predictors of false-negative findings and missed injuries. Radiology. 2003 Dec; 229(3):766-74. PMID: 14657314.
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    247. Brown MA, Sirlin C, Hoyt DB, Casola G. Screening ultrasound in blunt abdominal trauma. J Intensive Care Med. 2003 Sep-Oct; 18(5):253-60. PMID: 15035759.
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    248. Ritleng V, Sirlin C, Pfeffer M. Ru-, Rh-, and Pd-catalyzed C-C bond formation involving C-H activation and addition on unsaturated substrates: reactions and mechanistic aspects. Chem Rev. 2002 May; 102(5):1731-70. PMID: 11996548.
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    249. Girard MS, Kono Y, Sirlin C, Baker KG, Deiranieh LH, Mattrey RF. B-mode enhancement of the liver with microbubble contrast agent: a blinded study in rabbits with VX2 tumors. Acad Radiol. 2001 Aug; 8(8):734-40. PMID: 11508752.
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    250. Brown MA, Casola G, Sirlin C, Hoyt DB. Importance of evaluating organ parenchyma during screening abdominal ultrasonography after blunt trauma. J Ultrasound Med. 2001 Jun; 20(6):577-83; quiz 585. PMID: 11400931.
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    251. Sirlin C, Casola G, Brown MA, Patel N, Bendavid EJ, Hoyt DB. Quantification of fluid on screening ultrasonography for blunt abdominal trauma: a simple scoring system to predict severity of injury. J Ultrasound Med. 2001 Apr; 20(4):359-64. PMID: 11316314.
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    252. Sirlin C, Casola G, Brown MA, Patel N, Bendavid EJ, Hoyt DB. Patterns of fluid accumulation on screening ultrasonography for blunt abdominal trauma: comparison with site of injury. J Ultrasound Med. 2001 Apr; 20(4):351-7. PMID: 11316313.
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    253. Sirlin C, Casola G, Brown MA, Patel N, Bendavid EJ, Deutsch R, Hoyt DB. Us of blunt abdominal trauma: importance of free pelvic fluid in women of reproductive age. Radiology. 2001 Apr; 219(1):229-35. PMID: 11274562.
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    254. Sirlin C, Brossmann J, Boutin RD, Pathria MN, Convery FR, Bugbee W, Deutsch R, Lebeck LK, Resnick D. Shell osteochondral allografts of the knee: comparison of mr imaging findings and immunologic responses. Radiology. 2001 Apr; 219(1):35-43. PMID: 11274532.
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    255. Brown MA, Casola G, Sirlin C, Patel NY, Hoyt DB. Blunt abdominal trauma: screening us in 2,693 patients. Radiology. 2001 Feb; 218(2):352-8. PMID: 11161146.
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    256. Sirlin C, Lee YZ, Girard MS, Peterson TM, Steinbach GC, Baker KG, Mattrey RF. Contrast-enhanced B-mode US angiography in the assessment of experimental in vivo and in vitro atherosclerotic disease. Acad Radiol. 2001 Feb; 8(2):162-72. PMID: 11227645.
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    257. Sirlin C, Boutin RD, Brossmann J, Pathria MN, Convery FR, Bugbee W, Resnick D. Polydioxanone biodegradable pins in the knee: MR imaging. AJR Am J Roentgenol. 2001 Jan; 176(1):83-90. PMID: 11133543.
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    258. Sirlin C, Girard MS, Baker KG, Steinbach GC, Deiranieh LH, Mattrey RF. Effect of acquisition rate on liver and portal vein enhancement with microbubble contrast. Ultrasound Med Biol. 1999 Mar; 25(3):331-8. PMID: 10374977.
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    259. Girard MS, Sirlin C, Baker KG, Hall LA, Mattrey RF. Liver-tumor detection with ultrasound contrast: a blinded prospective study in rabbits. Acad Radiol. 1998 Apr; 5 Suppl 1:S189-91; discussion S199. PMID: 9561078.
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    260. Bergin CJ, Sirlin C, Hauschildt JP, Huynh TV, Auger WR, Fedullo PF, Kapelanski DP. Chronic thromboembolism: diagnosis with helical CT and MR imaging with angiographic and surgical correlation. Radiology. 1997 Sep; 204(3):695-702. PMID: 9280245.
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