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Claude Sirlin

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentRadiology
Address9500 Gilman Drive #0888
La Jolla CA 92093
Phone858-246-2203
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    Collapse Biography 
    Collapse Education and Training
    Havard UniversityB.A.Biology
    University of California, San FranciscoM.D.Medicine
    Collapse Awards and Honors
    Radiological Society of North America1996Research Resident Award
    Radiological Society of North America Research Roentgen 1998  - 1999Research Awards
    Elliot C. Lasser2000Award for Excellence in Research
    Stanford University2001 Radiology Teaching Award
    Society of Gastrointestinal Radiologists 2006Phillip H. Meyers Research Award
    Association of University Radiologists2007Radiology Research Alliance New Investigator Award
    ISMRM2008Outstanding Teacher Award: Case-Based Teaching Series
    UCSF2009Earl Miller Memorial Lecturer
    ESGAR2011SGR Honorary Lecturer

    Collapse Research 
    Collapse Research Activities and Funding
    QUS Technology for Diagnosis and Grading of Hepatic Steatosis in NAFLD
    NIH/NIDDK R01DK106419Jul 1, 2015 - May 31, 2020
    Role: Principal Investigator
    Development of MR-based biomarker panels for NAFLD - A NASH CRN Ancillary Study
    NIH/NIDDK R56DK090350Sep 30, 2010 - Aug 31, 2013
    Role: Principal Investigator
    Technical Validation of MRI Biomarkers of Liver Fat
    NIH/NIDDK R01DK088925Sep 15, 2010 - Jul 31, 2022
    Role: Principal Investigator
    MR Imaging of Non-Alcoholic Fatty Liver Disease
    NIH/NIDDK R01DK075128Sep 1, 2006 - Mar 31, 2012
    Role: Principal Investigator
    Training Clinical Scientists in Radiological Imaging
    NIH/NIBIB T32EB005970Apr 1, 2006 - Jul 31, 2023
    Role: Principal Investigator
    Transducible Molecular Probes for Imaging Tumors
    NIH/NCI K08CA102158Jul 18, 2003 - Jun 30, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Cerny M, Chernyak V, Olivié D, Billiard JS, Murphy-Lavallée J, Kielar AZ, Elsayes KM, Bourque L, Hooker JC, Sirlin CB, Tang A. LI-RADS Version 2018 Ancillary Features at MRI. Radiographics. 2018 Oct 05; 180052. PMID: 30289735.
      View in: PubMed
    2. Elsayes KM, Kielar AZ, Elmohr MM, Chernyak V, Masch WR, Furlan A, Marks RM, Cruite I, Fowler KJ, Tang A, Bashir MR, Hecht EM, Kamaya A, Jambhekar K, Kamath A, Arora S, Bijan B, Ash R, Kassam Z, Chaudhry H, McGahan JP, Yacoub JH, McInnes M, Fung AW, Shanbhogue K, Lee J, Deshmukh S, Horvat N, Mitchell DG, Do RKG, Surabhi VR, Szklaruk J, Sirlin CB. White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI. Abdom Radiol (NY). 2018 Oct; 43(10):2625-2642. PMID: 30155697.
      View in: PubMed
    3. Chernyak V, Fowler KJ, Kamaya A, Kielar AZ, Elsayes KM, Bashir MR, Kono Y, Do RK, Mitchell DG, Singal AG, Tang A, Sirlin CB. Liver Imaging Reporting and Data System (LI-RADS) Version 2018: Imaging of Hepatocellular Carcinoma in At-Risk Patients. Radiology. 2018 Sep 25; 181494. PMID: 30251931.
      View in: PubMed
    4. Li Q, Dhyani M, Grajo JR, Sirlin C, Samir AE. Current status of imaging in nonalcoholic fatty liver disease. World J Hepatol. 2018 Aug 27; 10(8):530-542. PMID: 30190781.
      View in: PubMed
    5. Hooker JC, Hamilton G, Park CC, Liao S, Wolfson T, Dehkordy SF, Hong CW, Mamidipalli A, Gamst A, Loomba R, Sirlin CB. Inter-reader agreement of magnetic resonance imaging proton density fat fraction and its longitudinal change in a clinical trial of adults with nonalcoholic steatohepatitis. Abdom Radiol (NY). 2018 Aug 20. PMID: 30128694.
      View in: PubMed
    6. Kim YY, Choi JY, Sirlin CB, An C, Kim MJ. Pitfalls and problems to be solved in the diagnostic CT/MRI Liver Imaging Reporting and Data System (LI-RADS). Eur Radiol. 2018 Aug 16. PMID: 30116960.
      View in: PubMed
    7. Kielar AZ, Elsayes KM, Chernyak V, Tang A, Sirlin CB. LI-RADS version 2018: What is new and what does this mean to my radiology reports? Abdom Radiol (NY). 2018 Aug 11. PMID: 30099621.
      View in: PubMed
    8. Wildman-Tobriner B, Middleton MM, Moylan CA, Rossi S, Flores O, Chang ZA, Abdelmalek MF, Sirlin CB, Bashir MR. Association Between Magnetic Resonance Imaging-Proton Density Fat Fraction and Liver Histology Features in Patients With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis. Gastroenterology. 2018 Jul 19. PMID: 30031769.
      View in: PubMed
    9. Elsayes KM, Chernyak V, Morshid AI, Tang A, Kielar AZ, Bashir MR, Sirlin CB. Spectrum of Pitfalls, Pseudolesions, and Potential Misdiagnoses in Cirrhosis. AJR Am J Roentgenol. 2018 Jul; 211(1):87-96. PMID: 29932761.
      View in: PubMed
    10. Hong CW, Marsh A, Wolfson T, Paige J, Dekhordy SF, Schlein AN, Housman E, Deiranieh LH, Li CQ, Wasnik AP, Jang HJ, Dietrich CF, Piscaglia F, Casola G, O'Boyle M, Richman KM, Valasek MA, Andre M, Loomba R, Sirlin CB. Reader agreement and accuracy of ultrasound features for hepatic steatosis. Abdom Radiol (NY). 2018 Jun 28. PMID: 29951900.
      View in: PubMed
    11. Hsu C, Caussy C, Imajo K, Chen J, Singh S, Kaulback K, Le MD, Hooker J, Tu X, Bettencourt R, Yin M, Sirlin CB, Ehman RL, Nakajima A, Loomba R. Magnetic Resonance vs Transient Elastography Analysis of Patients With Non-alcoholic Fatty Liver Disease: a Systematic Review and Pooled Analysis of Individual Participants. Clin Gastroenterol Hepatol. 2018 Jun 13. PMID: 29908362.
      View in: PubMed
    12. Han A, Labyed Y, Sy EZ, Boehringer AS, Andre MP, Erdman JW, Loomba R, Sirlin CB, O'Brien WD. Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease. Eur Radiol. 2018 Jun 04. PMID: 29869170.
      View in: PubMed
    13. Zhang Y, Fowler KJ, Hamilton G, Cui J, Sy EZ, Balanay M, Hooker JC, Szeverenyi NM, Sirlin CB. Liver fat imaging - a clinical overview of ultrasound, CT, and MR imaging. Br J Radiol. 2018 May 03; 20170959. PMID: 29722568.
      View in: PubMed
    14. Park CC, Hooker C, Hooker JC, Bass E, Haufe W, Schlein A, Covarrubias Y, Heba E, Bydder M, Wolfson T, Gamst A, Loomba R, Schwimmer J, Hernando D, Reeder SB, Middleton M, Sirlin CB, Hamilton G. Assessment of a high-SNR chemical-shift-encoded MRI with complex reconstruction for proton density fat fraction (PDFF) estimation overall and in the low-fat range. J Magn Reson Imaging. 2018 Apr 29. PMID: 29707848.
      View in: PubMed
    15. Lawitz EJ, Coste A, Poordad F, Alkhouri N, Loo N, McColgan BJ, Tarrant JM, Nguyen T, Han L, Chung C, Ray AS, McHutchison JG, Subramanian GM, Myers RP, Middleton MS, Sirlin C, Loomba R, Nyangau E, Fitch M, Li K, Hellerstein M. Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients with Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2018 Apr 26. PMID: 29705265.
      View in: PubMed
    16. Ajmera V, Park CC, Caussy C, Singh S, Hernandez C, Bettencourt R, Hooker J, Sy E, Behling C, Xu R, Middleton MS, Valasek MA, Faulkner C, Rizo E, Richards L, Sirlin CB, Loomba R. Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 Apr 13. PMID: 29660324.
      View in: PubMed
    17. Kielar AZ, Chernyak V, Bashir MR, Do RK, Fowler KJ, Mitchell DG, Cerny M, Elsayes KM, Santillan C, Kamaya A, Kono Y, Sirlin CB, Tang A. LI-RADS 2017: An update. J Magn Reson Imaging. 2018 Jun; 47(6):1459-1474. PMID: 29626376.
      View in: PubMed
    18. Marrero JA, Kulik LM, Sirlin C, Zhu AX, Finn RS, Abecassis MM, Roberts LR, Heimbach JK. Diagnosis, Staging and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018 Apr 06. PMID: 29624699.
      View in: PubMed
    19. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, Loomba R. Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2018 Mar 23. PMID: 29572891.
      View in: PubMed
    20. Kennedy P, Wagner M, Castéra L, Hong CW, Johnson CL, Sirlin CB, Taouli B. Quantitative Elastography Methods in Liver Disease: Current Evidence and Future Directions. Radiology. 2018 03; 286(3):738-763. PMID: 29461949.
      View in: PubMed
    21. Besa C, Lewis S, Pandharipande PV, Chhatwal J, Kamath A, Cooper N, Knight-Greenfield A, Babb JS, Boffetta P, Padron N, Sirlin CB, Taouli B. Erratum to: Hepatocellular carcinoma detection: diagnostic performance of a simulated abbreviated MRI protocol combining diffusion-weighted and T1-weighted imaging at the delayed phase post gadoxetic acid. Abdom Radiol (NY). 2018 Mar; 43(3):760. PMID: 28755071.
      View in: PubMed
    22. Caussy C, Alquiraish MH, Nguyen P, Hernandez C, Cepin S, Fortney LE, Ajmera V, Bettencourt R, Collier S, Hooker J, Sy E, Rizo E, Richards L, Sirlin CB, Loomba R. Optimal threshold of controlled attenuation parameter with MRI-PDFF as the gold standard for the detection of hepatic steatosis. Hepatology. 2018 Apr; 67(4):1348-1359. PMID: 29108123.
      View in: PubMed
    23. Dietrich CF, Averkiou M, Nielsen MB, Barr RG, Burns PN, Calliada F, Cantisani V, Choi B, Chammas MC, Clevert DA, Claudon M, Correas JM, Cui XW, Cosgrove D, D'Onofrio M, Dong Y, Eisenbrey J, Fontanilla T, Gilja OH, Ignee A, Jenssen C, Kono Y, Kudo M, Lassau N, Lyshchik A, Franca Meloni M, Moriyasu F, Nolsøe C, Piscaglia F, Radzina M, Saftoiu A, Sidhu PS, Sporea I, Schreiber-Dietrich D, Sirlin CB, Stanczak M, Weskott HP, Wilson SR, Willmann JK, Kim TK, Jang HJ, Vezeridis A, Westerway S. How to perform Contrast-Enhanced Ultrasound (CEUS). Ultrasound Int Open. 2018 Jan; 4(1):E2-E15. PMID: 29423461.
      View in: PubMed
    24. Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin CB. Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. Hepatology. 2018 Mar; 67(3):858-872. PMID: 29028128.
      View in: PubMed
    25. Brunt E, Aishima S, Clavien PA, Fowler K, Goodman Z, Gores G, Gouw A, Kagen A, Klimstra D, Komuta M, Kondo F, Miksad R, Nakano M, Nakanuma Y, Ng I, Paradis V, Nyun Park Y, Quaglia A, Roncalli M, Roskams T, Sakamoto M, Saxena R, Sempoux C, Sirlin C, Stueck A, Thung S, Tsui WMS, Wang XW, Wee A, Yano H, Yeh M, Zen Y, Zucman-Rossi J, Theise N. cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation. Hepatology. 2018 Jan 23. PMID: 29360137.
      View in: PubMed
    26. Han A, Andre MP, Deiranieh L, Housman E, Erdman JW, Loomba R, Sirlin CB, O'Brien WD. Repeatability and Reproducibility of the Ultrasonic Attenuation Coefficient and Backscatter Coefficient Measured in the Right Lobe of the Liver in Adults With Known or Suspected Nonalcoholic Fatty Liver Disease. J Ultrasound Med. 2018 Jan 23. PMID: 29359454.
      View in: PubMed
    27. Caussy C, Reeder SB, Sirlin CB, Loomba R. Non-invasive, quantitative assessment of liver fat by MRI-PDFF as an endpoint in NASH trials. Hepatology. 2018 Jan 21. PMID: 29356032.
      View in: PubMed
    28. Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Ehman RL, Loomba R. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. Clin Gastroenterol Hepatol. 2018 Jan 17. PMID: 29104128.
      View in: PubMed
    29. Santillan C, Chernyak V, Sirlin C. LI-RADS categories: concepts, definitions, and criteria. Abdom Radiol (NY). 2018 Jan; 43(1):101-110. PMID: 29038857.
      View in: PubMed
    30. Tang A, Cruite I, Mitchell DG, Sirlin CB. Hepatocellular carcinoma imaging systems: why they exist, how they have evolved, and how they differ. Abdom Radiol (NY). 2018 Jan; 43(1):3-12. PMID: 28840293.
      View in: PubMed
    31. Mitchell DG, Bashir MR, Sirlin CB. Management implications and outcomes of LI-RADS-2, -3, -4, and -M category observations. Abdom Radiol (NY). 2018 Jan; 43(1):143-148. PMID: 28779335.
      View in: PubMed
    32. Fowler KJ, Potretzke TA, Hope TA, Costa EA, Wilson SR, Sirlin CB, Tang A, Kielar A. Letter to the editor response. Abdom Radiol (NY). 2018 Jan; 43(1):239. PMID: 29167945.
      View in: PubMed
    33. Papadatos D, Fowler KJ, Kielar AZ, Cui J, Sirlin CB. Cirrhosis and LI-RADS. Abdom Radiol (NY). 2018 Jan; 43(1):26-40. PMID: 29218367.
      View in: PubMed
    34. Chernyak V, Santillan CS, Papadatos D, Sirlin CB. LI-RADS® algorithm: CT and MRI. Abdom Radiol (NY). 2018 Jan; 43(1):111-126. PMID: 28695233.
      View in: PubMed
    35. Sirlin CB, Kielar AZ, Tang A, Bashir MR. LI-RADS: a glimpse into the future. Abdom Radiol (NY). 2018 Jan; 43(1):231-236. PMID: 29318354.
      View in: PubMed
    36. Narsinh KH, Cui J, Papadatos D, Sirlin CB, Santillan CS. Hepatocarcinogenesis and LI-RADS. Abdom Radiol (NY). 2018 Jan; 43(1):158-168. PMID: 29209739.
      View in: PubMed
    37. Sirlin CB. The LI-RADS adventure-a personal statement. Abdom Radiol (NY). 2018 Jan; 43(1):1-2. PMID: 29282489.
      View in: PubMed
    38. Tang A, Hallouch O, Chernyak V, Kamaya A, Sirlin CB. Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis. Abdom Radiol (NY). 2018 Jan; 43(1):13-25. PMID: 28647765.
      View in: PubMed
    39. Tang A, Fowler KJ, Chernyak V, Chapman WC, Sirlin CB. LI-RADS and transplantation for hepatocellular carcinoma. Abdom Radiol (NY). 2018 Jan; 43(1):193-202. PMID: 28612162.
      View in: PubMed
    40. Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. 2018 01; 67(1):358-380. PMID: 28130846.
      View in: PubMed
    41. Wilson SR, Lyshchik A, Piscaglia F, Cosgrove D, Jang HJ, Sirlin C, Dietrich CF, Kim TK, Willmann JK, Kono Y. CEUS LI-RADS: algorithm, implementation, and key differences from CT/MRI. Abdom Radiol (NY). 2018 Jan; 43(1):127-142. PMID: 28819825.
      View in: PubMed
    42. Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin CB, Jacobsen GR. How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc. 2018 Apr; 32(4):1675-1682. PMID: 29218660.
      View in: PubMed
    43. Fraum TJ, Ludwig DR, Kilian S, Curtis WA, Pilgram TK, Sirlin CB, Fowler KJ. Epidemiology of Hepatic Steatosis at a Tertiary Care Center: An MRI-based Analysis. Acad Radiol. 2018 Mar; 25(3):317-327. PMID: 29199057.
      View in: PubMed
    44. Hong CW, Fazeli Dehkordy S, Hooker JC, Hamilton G, Sirlin CB. Fat Quantification in the Abdomen. Top Magn Reson Imaging. 2017 Dec; 26(6):221-227. PMID: 29176468.
      View in: PubMed
    45. Wang K, Manning P, Szeverenyi N, Wolfson T, Hamilton G, Middleton MS, Vaida F, Yin M, Glaser K, Ehman RL, Sirlin CB. Repeatability and reproducibility of 2D and 3D hepatic MR elastography with rigid and flexible drivers at end-expiration and end-inspiration in healthy volunteers. Abdom Radiol (NY). 2017 Dec; 42(12):2843-2854. PMID: 28612163.
      View in: PubMed
    46. Roberts LR, Sirlin CB, Zaiem F, Almasri J, Prokop LJ, Heimbach JK, Murad MH, Mohammed K. Imaging for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis. Hepatology. 2018 01; 67(1):401-421. PMID: 28859233.
      View in: PubMed
    47. Tang A, Bashir MR, Corwin MT, Cruite I, Dietrich CF, Do RKG, Ehman EC, Fowler KJ, Hussain HK, Jha RC, Karam AR, Mamidipalli A, Marks RM, Mitchell DG, Morgan TA, Ohliger MA, Shah A, Vu KN, Sirlin CB. Evidence Supporting LI-RADS Major Features for CT- and MR Imaging-based Diagnosis of Hepatocellular Carcinoma: A Systematic Review. Radiology. 2018 Jan; 286(1):29-48. PMID: 29166245.
      View in: PubMed
    48. Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin CB. Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. NMR Biomed. 2018 Jan; 31(1). PMID: 29130539.
      View in: PubMed
    49. Elsayes KM, Hooker JC, Agrons MM, Kielar AZ, Tang A, Fowler KJ, Chernyak V, Bashir MR, Kono Y, Do RK, Mitchell DG, Kamaya A, Hecht EM, Sirlin CB. 2017 Version of LI-RADS for CT and MR Imaging: An Update. Radiographics. 2017 Nov-Dec; 37(7):1994-2017. PMID: 29131761.
      View in: PubMed
    50. Fetzer DT, Rodgers SK, Harris AC, Kono Y, Wasnik AP, Kamaya A, Sirlin C. Screening and Surveillance of Hepatocellular Carcinoma: An Introduction to Ultrasound Liver Imaging Reporting and Data System. Radiol Clin North Am. 2017 Nov; 55(6):1197-1209. PMID: 28991560.
      View in: PubMed
    51. Fowler KJ, Tang A, Santillan C, Bhargavan-Chatfield M, Heiken J, Jha RC, Weinreb J, Hussain H, Mitchell DG, Bashir MR, Costa EAC, Cunha GM, Coombs L, Wolfson T, Gamst AC, Brancatelli G, Yeh B, Sirlin CB. Interreader Reliability of LI-RADS Version 2014 Algorithm and Imaging Features for Diagnosis of Hepatocellular Carcinoma: A Large International Multireader Study. Radiology. 2018 01; 286(1):173-185. PMID: 29091751.
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    52. Fazeli Dehkordy S, Fowler KJ, Wolfson T, Igarashi S, Lamas Constantino CP, Hooker JC, Hong CW, Mamidipalli A, Gamst AC, Hemming A, Sirlin CB. Technical report: gadoxetate-disodium-enhanced 2D R2* mapping: a novel approach for assessing bile ducts in living donors. Abdom Radiol (NY). 2017 Oct 31. PMID: 29086007.
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    53. Brouha SS, Nguyen P, Bettencourt R, Sirlin CB, Loomba R. Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. Eur Radiol. 2018 Apr; 28(4):1345-1355. PMID: 29058029.
      View in: PubMed
    54. Corwin MT, Lee AY, Fananapazir G, Loehfelm TW, Sarkar S, Sirlin CB. Nonstandardized Terminology to Describe Focal Liver Lesions in Patients at Risk for Hepatocellular Carcinoma: Implications Regarding Clinical Communication. AJR Am J Roentgenol. 2018 Jan; 210(1):85-90. PMID: 29023148.
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    55. Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. Hepatology. 2017 11; 66(5):1474-1485. PMID: 28493388.
      View in: PubMed
    56. Kim TK, Noh SY, Wilson SR, Kono Y, Piscaglia F, Jang HJ, Lyshchik A, Dietrich CF, Willmann JK, Vezeridis A, Sirlin CB. Contrast-enhanced ultrasound (CEUS) liver imaging reporting and data system (LI-RADS) 2017 - a review of important differences compared to the CT/MRI system. Clin Mol Hepatol. 2017 Dec; 23(4):280-289. PMID: 28911220.
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    57. Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn JP, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB, Sirlin CB. Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis. Radiology. 2018 02; 286(2):486-498. PMID: 28892458.
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    58. Hong CW, Mamidipalli A, Hooker JC, Hamilton G, Wolfson T, Chen DH, Fazeli Dehkordy S, Middleton MS, Reeder SB, Loomba R, Sirlin CB. MRI proton density fat fraction is robust across the biologically plausible range of triglyceride spectra in adults with nonalcoholic steatohepatitis. J Magn Reson Imaging. 2018 Apr; 47(4):995-1002. PMID: 28851124.
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    59. Hong CW, Wolfson T, Sy EZ, Schlein AN, Hooker JC, Fazeli Dehkordy S, Hamilton G, Reeder SB, Loomba R, Sirlin CB. Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. J Magn Reson Imaging. 2018 Apr; 47(4):988-994. PMID: 28842937.
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    60. Chernyak V, Kobi M, Flusberg M, Fruitman KC, Sirlin CB. Effect of threshold growth as a major feature on LI-RADS categorization. Abdom Radiol (NY). 2017 Aug; 42(8):2089-2100. PMID: 28352950.
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    61. Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, Hemming A, Andrews B, Salotti J, Richards L, Brenner DA, Sirlin CB, Loomba R. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. J Clin Invest. 2017 Jun 30; 127(7):2697-2704. PMID: 28628033.
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    62. Middleton MS, Heba ER, Hooker CA, Bashir MR, Fowler KJ, Sandrasegaran K, Brunt EM, Kleiner DE, Doo E, Van Natta ML, Lavine JE, Neuschwander-Tetri BA, Sanyal A, Loomba R, Sirlin CB. Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. Gastroenterology. 2017 09; 153(3):753-761. PMID: 28624576.
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    63. Sirlin C. Use of the Liver Imaging Reporting and Data System in Hepatocellular Carcinoma. Gastroenterol Hepatol (N Y). 2017 Jun; 13(6):363-365. PMID: 28690453.
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    64. Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 Feb; 47(2):418-424. PMID: 28543915.
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    65. Serai SD, Obuchowski NA, Venkatesh SK, Sirlin CB, Miller FH, Ashton E, Cole PE, Ehman RL. Repeatability of MR Elastography of Liver: A Meta-Analysis. Radiology. 2017 10; 285(1):92-100. PMID: 28530847.
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    66. Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5. PMID: 28467925.
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    67. Park CC, Hamilton G, Desai A, Zand KA, Wolfson T, Hooker JC, Costa E, Heba E, Clark L, Gamst A, Loomba R, Middleton MS, Sirlin CB. Effect of intravenous gadoxetate disodium and flip angle on hepatic proton density fat fraction estimation with six-echo, gradient-recalled-echo, magnitude-based MR imaging at 3T. Abdom Radiol (NY). 2017 Apr; 42(4):1189-1198. PMID: 28028556.
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    68. Piscaglia F, Wilson SR, Lyshchik A, Cosgrove D, Dietrich CF, Jang HJ, Kim TK, Salvatore V, Willmann JK, Sirlin CB, Kono Y. American College of Radiology Contrast Enhanced Ultrasound Liver Imaging Reporting and Data System (CEUS LI-RADS) for the diagnosis of Hepatocellular Carcinoma: a pictorial essay. Ultraschall Med. 2017 Jun; 38(3):320-324. PMID: 28329875.
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    140. Hernando D, Levin YS, Sirlin CB, Reeder SB. Quantification of liver iron with MRI: state of the art and remaining challenges. J Magn Reson Imaging. 2014 Nov; 40(5):1003-21. PMID: 24585403; PMCID: PMC4308740.
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    142. Patel NS, Peterson MR, Lin GY, Feldstein A, Schnabl B, Bettencourt R, Seki E, Sirlin CB, Loomba R. Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls. Gastroenterol Res Pract. 2013; 2013:498296. PMID: 24348536; PMCID: PMC3855930.
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    145. Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology. 2013 Dec; 58(6):1930-40. PMID: 23696515; PMCID: PMC4819962.
    146. Negrete LM, Middleton MS, Clark L, Wolfson T, Gamst AC, Lam J, Changchien C, Deyoung-Dominguez IM, Hamilton G, Loomba R, Schwimmer J, Sirlin CB. Inter-examination precision of magnitude-based MRI for estimation of segmental hepatic proton density fat fraction in obese subjects. J Magn Reson Imaging. 2014 May; 39(5):1265-71. PMID: 24136736; PMCID: PMC3984359.
    147. Awai HI, Newton KP, Sirlin CB, Behling C, Schwimmer JB. Evidence and recommendations for imaging liver fat in children, based on systematic review. Clin Gastroenterol Hepatol. 2014 May; 12(5):765-73. PMID: 24090729; PMCID: PMC3969892.
    148. Cruite I, Tang A, Sirlin CB. Imaging-based diagnostic systems for hepatocellular carcinoma. AJR Am J Roentgenol. 2013 Jul; 201(1):41-55. PMID: 23789657.
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    149. Zech CJ, Bartolozzi C, Bioulac-Sage P, Chow PK, Forner A, Grazioli L, Huppertz A, Laumonier H, Min Lee J, Murakami T, Ricke J, Sirlin CB. Consensus report of the Fifth International Forum for Liver MRI. AJR Am J Roentgenol. 2013 Jul; 201(1):97-107. PMID: 23789662.
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    150. Levin YS, Yokoo T, Wolfson T, Gamst AC, Collins J, Achmad EA, Hamilton G, Middleton MS, Loomba R, Sirlin CB. Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-echo MRI hepatic fat fraction estimation. J Magn Reson Imaging. 2014 Mar; 39(3):567-75. PMID: 23720420; PMCID: PMC3760998.
    151. Liau J, Shiehmorteza M, Girard OM, Sirlin CB, Bydder M. Evaluation of MRI fat fraction in the liver and spine pre and post SPIO infusion. Magn Reson Imaging. 2013 Jul; 31(6):1012-6. PMID: 23602721; PMCID: PMC3676690.
    152. Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7. PMID: 23596052; PMCID: PMC3732566.
    153. Tang A, Cruite I, Sirlin CB. Toward a standardized system for hepatocellular carcinoma diagnosis using computed tomography and MRI. Expert Rev Gastroenterol Hepatol. 2013 Mar; 7(3):269-79. PMID: 23445236.
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    154. Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31. PMID: 23382291; PMCID: PMC3632805.
    155. Murphy P, Wolfson T, Gamst A, Sirlin C, Bydder M. Error model for reduction of cardiac and respiratory motion effects in quantitative liver DW-MRI. Magn Reson Med. 2013 Nov; 70(5):1460-9. PMID: 23280855; PMCID: PMC4142067.
    156. Mashhood A, Railkar R, Yokoo T, Levin Y, Clark L, Fox-Bosetti S, Middleton MS, Riek J, Kauh E, Dardzinski BJ, Williams D, Sirlin C, Shire NJ. Reproducibility of hepatic fat fraction measurement by magnetic resonance imaging. J Magn Reson Imaging. 2013 Jun; 37(6):1359-70. PMID: 23172799.
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    157. Sirlin CB. Invited commentary. Radiographics. 2012 Nov-Dec; 32(7):1995-8; discussion 1998. PMID: 23304704.
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    158. Vidimar V, Meng X, Klajner M, Licona C, Fetzer L, Harlepp S, Hébraud P, Sidhoum M, Sirlin C, Loeffler JP, Mellitzer G, Sava G, Pfeffer M, Gaiddon C. Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity. Biochem Pharmacol. 2012 Dec 01; 84(11):1428-36. PMID: 22964219.
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    159. Bahl G, Cruite I, Wolfson T, Gamst AC, Collins JM, Chavez AD, Barakat F, Hassanein T, Sirlin CB. Noninvasive classification of hepatic fibrosis based on texture parameters from double contrast-enhanced magnetic resonance images. J Magn Reson Imaging. 2012 Nov; 36(5):1154-61. PMID: 22851409; PMCID: PMC4803477.
    160. Reeder SB, Hu HH, Sirlin CB. Proton density fat-fraction: a standardized MR-based biomarker of tissue fat concentration. J Magn Reson Imaging. 2012 Nov; 36(5):1011-4. PMID: 22777847; PMCID: PMC4779595.
    161. Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology. 2012 Sep; 56(3):922-32. PMID: 22431131; PMCID: PMC3400720.
    162. Campos JT, Sirlin CB, Choi JY. Focal hepatic lesions in Gd-EOB-DTPA enhanced MRI: the atlas. Insights Imaging. 2012 Oct; 3(5):451-74. PMID: 22700119; PMCID: PMC3443279.
    163. Hu HH, Börnert P, Hernando D, Kellman P, Ma J, Reeder S, Sirlin C. ISMRM workshop on fat-water separation: insights, applications and progress in MRI. Magn Reson Med. 2012 Aug; 68(2):378-88. PMID: 22693111; PMCID: PMC3575097.
    164. Kang BK, Yu ES, Lee SS, Lee Y, Kim N, Sirlin CB, Cho EY, Yeom SK, Byun JH, Park SH, Lee MG. Hepatic fat quantification: a prospective comparison of magnetic resonance spectroscopy and analysis methods for chemical-shift gradient echo magnetic resonance imaging with histologic assessment as the reference standard. Invest Radiol. 2012 Jun; 47(6):368-75. PMID: 22543969.
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    165. Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor d agonist. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):E1369-76. PMID: 22538808; PMCID: PMC3361396.
    166. Lee JT, Liau J, Murphy P, Schroeder ME, Sirlin CB, Bydder M. Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging. Magn Reson Imaging. 2012 May; 30(4):572-8. PMID: 22285877; PMCID: PMC3327769.
    167. Hansen KH, Schroeder ME, Hamilton G, Sirlin CB, Bydder M. Robustness of fat quantification using chemical shift imaging. Magn Reson Imaging. 2012 Feb; 30(2):151-7. PMID: 22055856; PMCID: PMC3254829.
    168. Reeder SB, Cruite I, Hamilton G, Sirlin CB. Quantitative Assessment of Liver Fat with Magnetic Resonance Imaging and Spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):spcone. PMID: 22025886.
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    169. Reeder SB, Cruite I, Hamilton G, Sirlin CB. Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):729-49. PMID: 21928307.
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    170. Goodwin MD, Dobson JE, Sirlin CB, Lim BG, Stella DL. Diagnostic challenges and pitfalls in MR imaging with hepatocyte-specific contrast agents. Radiographics. 2011 Oct; 31(6):1547-68. PMID: 21997981.
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    171. Liau J, Lee J, Schroeder ME, Sirlin CB, Bydder M. Cardiac motion in diffusion-weighted MRI of the liver: artifact and a method of correction. J Magn Reson Imaging. 2012 Feb; 35(2):318-27. PMID: 21959926; PMCID: PMC3252483.
    172. Fetzer L, Boff B, Ali M, Xiangjun M, Collin JP, Sirlin C, Gaiddon C, Pfeffer M. Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: passing the nanomolar barrier. Dalton Trans. 2011 Sep 21; 40(35):8869-78. PMID: 21837342.
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    173. Kang GH, Cruite I, Shiehmorteza M, Wolfson T, Gamst AC, Hamilton G, Bydder M, Middleton MS, Sirlin CB. Reproducibility of MRI-determined proton density fat fraction across two different MR scanner platforms. J Magn Reson Imaging. 2011 Oct; 34(4):928-34. PMID: 21769986; PMCID: PMC4803481.
    174. Sirlin CB. Science to practice: Can T1rho imaging be used to diagnose and assess the severity of hepatic fibrosis? Radiology. 2011 Jun; 259(3):619-20. PMID: 21602499.
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    175. Rajaraman S, Rodriguez JJ, Graff C, Altbach MI, Dragovich T, Sirlin CB, Korn RL, Raghunand N. Automated registration of sequential breath-hold dynamic contrast-enhanced MR images: a comparison of three techniques. Magn Reson Imaging. 2011 Jun; 29(5):668-82. PMID: 21531108; PMCID: PMC3100446.
    176. Hines CD, Frydrychowicz A, Hamilton G, Tudorascu DL, Vigen KK, Yu H, McKenzie CA, Sirlin CB, Brittain JH, Reeder SB. T(1) independent, T(2) (*) corrected chemical shift based fat-water separation with multi-peak fat spectral modeling is an accurate and precise measure of hepatic steatosis. J Magn Reson Imaging. 2011 Apr; 33(4):873-81. PMID: 21448952; PMCID: PMC3130738.
    177. Yu H, Shimakawa A, Hines CD, McKenzie CA, Hamilton G, Sirlin CB, Brittain JH, Reeder SB. Combination of complex-based and magnitude-based multiecho water-fat separation for accurate quantification of fat-fraction. Magn Reson Med. 2011 Jul; 66(1):199-206. PMID: 21695724; PMCID: PMC3130743.
    178. Barshop NJ, Capparelli EV, Sirlin CB, Schwimmer JB, Lavine JE. Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):198-202. PMID: 21240014; PMCID: PMC3059772.
    179. Meisamy S, Hines CD, Hamilton G, Sirlin CB, McKenzie CA, Yu H, Brittain JH, Reeder SB. Quantification of hepatic steatosis with T1-independent, T2-corrected MR imaging with spectral modeling of fat: blinded comparison with MR spectroscopy. Radiology. 2011 Mar; 258(3):767-75. PMID: 21248233; PMCID: PMC3042638.
    180. Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB. Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology. 2011 Mar; 258(3):749-59. PMID: 21212366; PMCID: PMC3042639.
    181. Bydder M, Yokoo T, Yu H, Carl M, Reeder SB, Sirlin CB. Constraining the initial phase in water-fat separation. Magn Reson Imaging. 2011 Feb; 29(2):216-21. PMID: 21159457; PMCID: PMC3053064.
    182. Hamilton G, Yokoo T, Bydder M, Cruite I, Schroeder ME, Sirlin CB, Middleton MS. In vivo characterization of the liver fat ¹H MR spectrum. NMR Biomed. 2011 Aug; 24(7):784-90. PMID: 21834002; PMCID: PMC3860876.
    183. Klajner M, Hebraud P, Sirlin C, Gaiddon C, Harlepp S. DNA binding to an anticancer organo-ruthenium complex. J Phys Chem B. 2010 Nov 11; 114(44):14041-7. PMID: 20961087.
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    184. Karçaaltincaba M, Sirlin CB. CT and MRI of diffuse lobar involvement pattern in liver pathology. Diagn Interv Radiol. 2011 Dec; 17(4):334-42. PMID: 21053176.
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    185. Dieng PS, Sirlin C. Recognition of chiral carboxylic anions by artificial receptors. Int J Mol Sci. 2010 Sep 15; 11(9):3334-48. PMID: 20957098; PMCID: PMC2956098.
    186. Sirlin CB, Reeder SB. Magnetic resonance imaging quantification of liver iron. Magn Reson Imaging Clin N Am. 2010 Aug; 18(3):359-81, ix. PMID: 21094445; PMCID: PMC3430384.
    187. Reeder SB, Sirlin CB. Quantification of liver fat with magnetic resonance imaging. Magn Reson Imaging Clin N Am. 2010 Aug; 18(3):337-57, ix. PMID: 21094444; PMCID: PMC3002753.
    188. Ganesan K, Achmad E, Sirlin CB, Bouvet M, Datnow B, Weidner N, Peterson MR. Amphicrine carcinoma of the liver. Ann Diagn Pathol. 2011 Oct; 15(5):355-7. PMID: 20952282.
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    189. Cruite I, Schroeder M, Merkle EM, Sirlin CB. Gadoxetate disodium-enhanced MRI of the liver: part 2, protocol optimization and lesion appearance in the cirrhotic liver. AJR Am J Roentgenol. 2010 Jul; 195(1):29-41. PMID: 20566795.
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    190. Ringe KI, Husarik DB, Sirlin CB, Merkle EM. Gadoxetate disodium-enhanced MRI of the liver: part 1, protocol optimization and lesion appearance in the noncirrhotic liver. AJR Am J Roentgenol. 2010 Jul; 195(1):13-28. PMID: 20566794.
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    191. Mwangi I, Hanna RF, Kased N, Malek P, Shiehmorteza M, Wolfson T, Gamst A, Sirlin C. Apparent diffusion coefficient of fibrosis and regenerative nodules in the cirrhotic liver at MRI. AJR Am J Roentgenol. 2010 Jun; 194(6):1515-22. PMID: 20489091.
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    192. Yokoo T, Bae WC, Hamilton G, Karimi A, Borgstede JP, Bowen BC, Sirlin CB, Chung CB, Crues JV, Bradley WG, Bydder GM. A quantitative approach to sequence and image weighting. J Comput Assist Tomogr. 2010 May-Jun; 34(3):317-31. PMID: 20498530.
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    193. Bydder M, Shiehmorteza M, Yokoo T, Sugay S, Middleton MS, Girard O, Schroeder ME, Wolfson T, Gamst A, Sirlin C. Assessment of liver fat quantification in the presence of iron. Magn Reson Imaging. 2010 Jul; 28(6):767-76. PMID: 20409663; PMCID: PMC2924146.
    194. Schwimmer JB, Dunn W, Norman GJ, Pardee PE, Middleton MS, Kerkar N, Sirlin CB. SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology. 2010 Apr; 138(4):1357-64, 1364.e1-2. PMID: 20064512; PMCID: PMC2846968.
    195. Lindbäck SM, Gabbert C, Johnson BL, Smorodinsky E, Sirlin CB, Garcia N, Pardee PE, Kistler KD, Schwimmer JB. Pediatric nonalcoholic fatty liver disease: a comprehensive review. Adv Pediatr. 2010; 57(1):85-140. PMID: 21056736.
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    196. Mazhar SM, Shiehmorteza M, Kohl CA, Middleton MS, Sirlin CB. Nephrogenic systemic fibrosis in liver disease: a systematic review. J Magn Reson Imaging. 2009 Dec; 30(6):1313-22. PMID: 19937937; PMCID: PMC2844250.
    197. Sirlin CB. Noninvasive imaging biomarkers for steatosis assessment. Liver Transpl. 2009 Nov; 15(11):1389-91. PMID: 19877212.
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    198. Faria SC, Ganesan K, Mwangi I, Shiehmorteza M, Viamonte B, Mazhar S, Peterson M, Kono Y, Santillan C, Casola G, Sirlin CB. MR imaging of liver fibrosis: current state of the art. Radiographics. 2009 Oct; 29(6):1615-35. PMID: 19959511.
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    199. Loomba R, Sirlin CB, Schwimmer JB, Lavine JE. Advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2009 Oct; 50(4):1282-93. PMID: 19637286; PMCID: PMC2757471.
    200. Hyder JA, Allison MA, Barrett-Connor E, Detrano R, Wong ND, Sirlin C, Gapstur SM, Ouyang P, Carr JJ, Criqui MH. Bone mineral density and atherosclerosis: the Multi-Ethnic Study of Atherosclerosis, Abdominal Aortic Calcium Study. Atherosclerosis. 2010 Mar; 209(1):283-9. PMID: 19819456.
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    201. Shiehmorteza M, Sirlin CB, Wolfson T, Gamst A, Soumekh AE, Heaton SP, Kohl CA, Pinto N, Bydder M. Effect of shot number on the calculated apparent diffusion coefficient in phantoms and in human liver in diffusion-weighted echo-planar imaging. J Magn Reson Imaging. 2009 Sep; 30(3):547-53. PMID: 19711409.
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    202. Sirlin CB. Invited commentary. Radiographics. 2009 Sep-Oct; 29(5):1277-80. PMID: 19764109.
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    203. Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB. Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging. 2009 Jul; 30(1):145-52. PMID: 19557733; PMCID: PMC2982807.
    204. Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP. Cancer Res. 2009 Jul 01; 69(13):5458-66. PMID: 19549908.
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    205. Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology. 2009 Apr; 251(1):67-76. PMID: 19221054; PMCID: PMC2663579.
    206. Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 2009 May; 136(5):1585-92. PMID: 19208353; PMCID: PMC3397140.
    207. Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB. Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics. 2009 Jan-Feb; 29(1):231-60. PMID: 19168847.
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    208. Hyder JA, Allison MA, Wong N, Papa A, Lang TF, Sirlin C, Gapstur SM, Ouyang P, Carr JJ, Criqui MH. Association of coronary artery and aortic calcium with lumbar bone density: the MESA Abdominal Aortic Calcium Study. Am J Epidemiol. 2009 Jan 15; 169(2):186-94. PMID: 19064643.
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    209. Mazhar SM, Shiehmorteza M, Sirlin CB. Noninvasive assessment of hepatic steatosis. Clin Gastroenterol Hepatol. 2009 Feb; 7(2):135-40. PMID: 19118644.
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    210. Kohl CA, Sirlin CB, Peterson MR. A new liver explant fixation technique. Arch Pathol Lab Med. 2008 Dec; 132(12):1859-60. PMID: 19061279.
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    211. Yokoo T, Collins JM, Hanna RF, Bydder M, Middleton MS, Sirlin CB. Effects of intravenous gadolinium administration and flip angle on the assessment of liver fat signal fraction with opposed-phase and in-phase imaging. J Magn Reson Imaging. 2008 Jul; 28(1):246-51. PMID: 18581393.
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    212. Bydder M, Hamilton G, Yokoo T, Sirlin CB. Optimal phased-array combination for spectroscopy. Magn Reson Imaging. 2008 Jul; 26(6):847-50. PMID: 18486392; PMCID: PMC2868913.
    213. Hanna RF, Aguirre DA, Kased N, Emery SC, Peterson MR, Sirlin CB. Cirrhosis-associated hepatocellular nodules: correlation of histopathologic and MR imaging features. Radiographics. 2008 May-Jun; 28(3):747-69. PMID: 18480482.
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    214. Yeh BM, Joe BN, Sirlin CB, Webb EM, Westphalen AC, Qayyum A, Coakley FV. Vascular contact with soft tissue: a sign of mesenteric masses at computed tomography. J Comput Assist Tomogr. 2008 Mar-Apr; 32(2):185-90. PMID: 18379299; PMCID: PMC2724062.
    215. Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin CB. Relaxation effects in the quantification of fat using gradient echo imaging. Magn Reson Imaging. 2008 Apr; 26(3):347-59. PMID: 18093781; PMCID: PMC2386876.
    216. Hughes-Cassidy F, Wong J, Aguirre D, Chavez AD, Wolfson T, Gamst A, Sirlin C. Transient homogeneously enhancing hepatic masses: can size predict benignity? AJR Am J Roentgenol. 2008 Feb; 190(2):300-7. PMID: 18212213.
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    217. Hanna RF, Kased N, Kwan SW, Gamst AC, Santosa AC, Hassanein T, Sirlin CB. Double-contrast MRI for accurate staging of hepatocellular carcinoma in patients with cirrhosis. AJR Am J Roentgenol. 2008 Jan; 190(1):47-57. PMID: 18094293.
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    218. Leite NP, Kased N, Hanna RF, Brown MA, Pereira JM, Cunha R, Sirlin CB. Cross-sectional imaging of extranodal involvement in abdominopelvic lymphoproliferative malignancies. Radiographics. 2007 Nov-Dec; 27(6):1613-34. PMID: 18025507.
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    219. Hughes-Cassidy F, Chavez AD, Schlang A, Hassanein T, Gamst A, Wolfson T, Sirlin C. Superparamagnetic iron oxides and low molecular weight gadolinium chelates are synergistic for direct visualization of advanced liver fibrosis. J Magn Reson Imaging. 2007 Sep; 26(3):728-37. PMID: 17685418.
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    220. Kuo MD, Gollub J, Sirlin CB, Ooi C, Chen X. Radiogenomic analysis to identify imaging phenotypes associated with drug response gene expression programs in hepatocellular carcinoma. J Vasc Interv Radiol. 2007 Jul; 18(7):821-31. PMID: 17609439.
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    221. Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nat Biotechnol. 2007 Jun; 25(6):675-80. PMID: 17515910.
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    222. Hamer OW, Schlottmann K, Sirlin CB, Feuerbach S. Technology insight: advances in liver imaging. Nat Clin Pract Gastroenterol Hepatol. 2007 Apr; 4(4):215-28. PMID: 17404589.
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    223. Tamburrini S, Brunetti A, Brown M, Sirlin C, Casola G. Acute appendicitis: diagnostic value of nonenhanced CT with selective use of contrast in routine clinical settings. Eur Radiol. 2007 Aug; 17(8):2055-61. PMID: 17180324.
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    224. Hamer OW, Aguirre DA, Casola G, Lavine JE, Woenckhaus M, Sirlin CB. Fatty liver: imaging patterns and pitfalls. Radiographics. 2006 Nov-Dec; 26(6):1637-53. PMID: 17102041.
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    225. Hall FM, Casola G, Sirlin CB, Furtado CD, Aguirre DA, Brown MA. Callback and follow-up guidelines for whole-body CT screening. Radiology. 2006 Nov; 241(2):627-8; author reply 628-9. PMID: 17057082.
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    226. Gandhi SN, Brown MA, Wong JG, Aguirre DA, Sirlin CB. MR contrast agents for liver imaging: what, when, how. Radiographics. 2006 Nov-Dec; 26(6):1621-36. PMID: 17102040.
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    227. Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE. Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):413-27. PMID: 17033514.
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    228. Aguirre DA, Behling CA, Alpert E, Hassanein TI, Sirlin CB. Liver fibrosis: noninvasive diagnosis with double contrast material-enhanced MR imaging. Radiology. 2006 May; 239(2):425-37. PMID: 16641352.
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    229. Brown MA, Mattrey RF, Stamato S, Sirlin CB. MRI of the female pelvis using vaginal gel. AJR Am J Roentgenol. 2005 Nov; 185(5):1221-7. PMID: 16247138.
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    230. Aguirre DA, Santosa AC, Casola G, Sirlin CB. Abdominal wall hernias: imaging features, complications, and diagnostic pitfalls at multi-detector row CT. Radiographics. 2005 Nov-Dec; 25(6):1501-20. PMID: 16284131.
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    231. Yoo RY, Sirlin CB, Gottschalk M, Chang RJ. Ovarian imaging by magnetic resonance in obese adolescent girls with polycystic ovary syndrome: a pilot study. Fertil Steril. 2005 Oct; 84(4):985-95. PMID: 16213854.
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    232. Hamer OW, Sirlin CB, Strotzer M, Borisch I, Zorger N, Feuerbach S, Völk M. Chest radiography with a flat-panel detector: image quality with dose reduction after copper filtration. Radiology. 2005 Nov; 237(2):691-700. PMID: 16192324.
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    233. Furtado CD, Aguirre DA, Sirlin CB, Dang D, Stamato SK, Lee P, Sani F, Brown MA, Levin DL, Casola G. Whole-body CT screening: spectrum of findings and recommendations in 1192 patients. Radiology. 2005 Nov; 237(2):385-94. PMID: 16170016.
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    234. Hamer OW, Aguirre DA, Casola G, Sirlin CB. Imaging features of perivascular fatty infiltration of the liver: initial observations. Radiology. 2005 Oct; 237(1):159-69. PMID: 16100085.
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    235. Pinto Leite N, Pereira JM, Cunha R, Pinto P, Sirlin C. CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings. AJR Am J Roentgenol. 2005 Aug; 185(2):406-17. PMID: 16037513.
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    236. Tamburrini S, Brunetti A, Brown M, Sirlin CB, Casola G. CT appearance of the normal appendix in adults. Eur Radiol. 2005 Oct; 15(10):2096-103. PMID: 15912331.
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    237. Brown MA, Sirlin CB. Female pelvis. Magn Reson Imaging Clin N Am. 2005 May; 13(2):381-95. PMID: 15935318.
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    238. Sortais JB, Ritleng V, Voelklin A, Holuigue A, Smail H, Barloy L, Sirlin C, Verzijl GK, Boogers JA, de Vries AH, de Vries JG, Pfeffer M. Cycloruthenated primary and secondary amines as efficient catalyst precursors for asymmetric transfer hydrogenation. Org Lett. 2005 Mar 31; 7(7):1247-50. PMID: 15787478.
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    239. Farahmand N, Sirlin CB, Brown MA, Shragg GP, Fortlage D, Hoyt DB, Casola G. Hypotensive patients with blunt abdominal trauma: performance of screening US. Radiology. 2005 May; 235(2):436-43. PMID: 15798158.
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    240. Ryabov AD, Le Lagadec R, Estevez H, Toscano RA, Hernandez S, Alexandrova L, Kurova VS, Fischer A, Sirlin C, Pfeffer M. Synthesis, characterization, and electrochemistry of biorelevant photosensitive low-potential orthometalated ruthenium complexes. Inorg Chem. 2005 Mar 07; 44(5):1626-34. PMID: 15733006.
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    241. Laufik M, Buono D, Casola G, Sirlin C. Delayed traumatic bladder rupture. AJR Am J Roentgenol. 2005 Mar; 184(3 Suppl):S99-S101. PMID: 15728038.
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    242. Brown MA, Sirlin CB, Farahmand N, Hoyt DB, Casola G. Screening sonography in pregnant patients with blunt abdominal trauma. J Ultrasound Med. 2005 Feb; 24(2):175-81; quiz 183-184. PMID: 15661948.
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    243. Pereira JM, Sirlin CB, Pinto PS, Casola G. CT and MR imaging of extrahepatic fatty masses of the abdomen and pelvis: techniques, diagnosis, differential diagnosis, and pitfalls. Radiographics. 2005 Jan-Feb; 25(1):69-85. PMID: 15653588.
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    244. Sirlin CB, Vera DR, Corbeil JA, Caballero MB, Buxton RB, Mattrey RF. Gadolinium-DTPA-dextran: a macromolecular MR blood pool contrast agent. Acad Radiol. 2004 Dec; 11(12):1361-9. PMID: 15596374.
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    245. Aguirre DA, Casola G, Sirlin C. Abdominal wall hernias: MDCT findings. AJR Am J Roentgenol. 2004 Sep; 183(3):681-90. PMID: 15333356.
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    246. Pereira JM, Sirlin CB, Pinto PS, Jeffrey RB, Stella DL, Casola G. Disproportionate fat stranding: a helpful CT sign in patients with acute abdominal pain. Radiographics. 2004 May-Jun; 24(3):703-15. PMID: 15143223.
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    247. Pinto PS, Sirlin CB, Andrade-Barreto OA, Brown MA, Mindelzun RE, Mattrey RF. Cisterna chyli at routine abdominal MR imaging: a normal anatomic structure in the retrocrural space. Radiographics. 2004 May-Jun; 24(3):809-17. PMID: 15143230.
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    248. Sirlin CB, Brown MA, Andrade-Barreto OA, Deutsch R, Fortlage DA, Hoyt DB, Casola G. Blunt abdominal trauma: clinical value of negative screening US scans. Radiology. 2004 Mar; 230(3):661-8. PMID: 14990832.
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    249. Kono Y, Pinnell SP, Sirlin CB, Sparks SR, Georgy B, Wong W, Mattrey RF. Carotid arteries: contrast-enhanced US angiography--preliminary clinical experience. Radiology. 2004 Feb; 230(2):561-8. PMID: 14699188.
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    250. Sirlin CB, Brown MA, Deutsch R, Andrade-Barreto OA, Fortlage DA, Hoyt DB, Casola G. Screening US for blunt abdominal trauma: objective predictors of false-negative findings and missed injuries. Radiology. 2003 Dec; 229(3):766-74. PMID: 14657314.
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    251. Brown MA, Sirlin CB, Hoyt DB, Casola G. Screening ultrasound in blunt abdominal trauma. J Intensive Care Med. 2003 Sep-Oct; 18(5):253-60. PMID: 15035759.
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    252. Ritleng V, Sirlin C, Pfeffer M. Ru-, Rh-, and Pd-catalyzed C-C bond formation involving C-H activation and addition on unsaturated substrates: reactions and mechanistic aspects. Chem Rev. 2002 May; 102(5):1731-70. PMID: 11996548.
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