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Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics. Nat Commun. 2024 Nov 29; 15(1):10387.
Munro D, Ehsan N, Esmaeili-Fard SM, Gusev A, Palmer AA, Mohammadi P. PMID: 39613793.
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Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct. Elife. 2024 Nov 01; 12.
de Guglielmo G, Carrette L, Kallupi M, Brennan M, Boomhower B, Maturin L, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Martinez AR, Velarde N, Othman D, Sichel B, Ramborger J, Lau J, Kononoff J, Kimbrough A, Simpson S, Smith LC, Shankar K, Bonnet-Zahedi S, Sneddon EA, Avelar A, Plasil SL, Mosquera J, Crook C, Chun L, Vang A, Milan KK, Schweitzer P, Lin B, Peng B, Chitre AS, Polesskaya O, Solberg Woods LC, Palmer AA, George O. PMID: 39484794; PMCID: PMC11530236.
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PubMed Mentions: Fields:
Translation:
Animals
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An emerging multi-omic understanding of the genetics of opioid addiction. J Clin Invest. 2024 Oct 15; 134(20).
Johnson EO, Fisher HS, Sullivan KA, Corradin O, Sanchez-Roige S, Gaddis NC, Sami YN, Townsend A, Teixeira Prates E, Pavicic M, Kruse P, Chesler EJ, Palmer AA, Troiani V, Bubier JA, Jacobson DA, Maher BS. PMID: 39403933; PMCID: PMC11473141.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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PAGER: A novel genotype encoding strategy for modeling deviations from additivity in complex trait association studies. BioData Min. 2024 Oct 11; 17(1):41.
Freda PJ, Ghosh A, Bhandary P, Matsumoto N, Chitre AS, Zhou J, Hall MA, Palmer AA, Obafemi-Ajayi T, Moore JH. PMID: 39394173; PMCID: PMC11468469.
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PubMed Mentions:
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Sex-specific Concordance of Striatal Transcriptional Signatures of Opioid Addiction in Human and Rodent Brains. Res Sq. 2024 Sep 24.
Logan R, Shelton M, Horan N, Xue X, Maturin L, Eacret D, Michaud J, Singh N, Williams B, Gamble M, Seggio J, Kuppe-Fish M, Phan B, Tseng G, Blendy J, Woods LS, Palmer A, George O, Seney M. PMID: 39399686; PMCID: PMC11469374.
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Publisher Correction: Hazardous drinking and alcohol use disorders. Nat Rev Dis Primers. 2024 Sep 20; 10(1):69.
MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J. PMID: 39304664.
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PubMed Mentions: Fields:
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Y and Mitochondrial Chromosomes in the Heterogeneous Stock Rat Population. G3 (Bethesda). 2024 Sep 09.
Okamoto F, Chitre AS, Sanches TM, Chen D, Munro D, Aron AT, Beeson A, Bimschleger HV, Eid M, Martinez AGG, Han W, Holl K, Jackson T, Johnson BB, King CP, Kuhn BN, Lamparelli AC, Netzley AH, Nguyen KH, Peng BF, Tripi JA, Wang T, Ziegler KS, Adams DJ, Baud A, Carrette LLG, Chen H, de Guglielmo G, Dorrestein P, George O, Ishiwari K, Jablonski MM, Jhou TC, Kallupi M, Knight R, Meyer PJ, Woods LCS, Polesskaya O, Palmer AA. PMID: 39250761.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency. bioRxiv. 2024 Aug 04.
Kuhn BN, Cannella N, Crow AD, Lunerti V, Gupta A, Walterhouse SJ, Allen C, Chalhoub RM, Dereschewitz E, Roberts AT, Cockerham M, Beeson A, Nall RW, Palmer AA, Hardiman G, Solberg Woods LC, Chung D, Ciccocioppo R, Kalivas PW. PMID: 39211180; PMCID: PMC11361156.
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PubMed Mentions:
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Genome-wide association study of delay discounting in Heterogeneous Stock rats. Genes Brain Behav. 2024 Aug; 23(4):e12909.
Lara MK, Chitre AS, Chen D, Johnson BB, Nguyen KM, Cohen KA, Muckadam SA, Lin B, Ziegler S, Beeson A, Sanches TM, Solberg Woods LC, Polesskaya O, Palmer AA, Mitchell SH. PMID: 39119916; PMCID: PMC11310854.
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PubMed Mentions: Fields:
Translation:
Animals
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A Cost-effective, High-throughput, Highly Accurate Genotyping Method for Outbred Populations. bioRxiv. 2024 Jul 18.
Chen D, Chitre AS, Nguyen KH, Cohen K, Peng B, Ziegler KS, Okamoto F, Lin B, Johnson BB, Sanches TM, Cheng R, Polesskaya O, Palmer AA. PMID: 39071405; PMCID: PMC11275765.
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PubMed Mentions:
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Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats. bioRxiv. 2024 Jun 25.
Kuhn BN, Cannella N, Chitre AS, Nguyen KH, Cohen K, Chen D, Peng B, Ziegler KS, Lin B, Johnson BB, Missfeldt Sanches T, Crow AD, Lunerti V, Gupta A, Dereschewitz E, Soverchia L, Hopkins JL, Roberts AT, Ubaldi M, Abdulmalek S, Kinen A, Hardiman G, Chung D, Polesskaya O, Solberg Woods LC, Ciccocioppo R, Kalivas PW, Palmer AA. PMID: 38712202; PMCID: PMC11071306.
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Rare and common variants associated with alcohol consumption identify a conserved molecular network. Alcohol Clin Exp Res (Hoboken). 2024 Jun 21.
Leger BS, Meredith JJ, Ideker T, Sanchez-Roige S, Palmer AA. PMID: 39031522.
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PubMed Mentions: Fields:
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Genome-wide association studies of lifetime and frequency cannabis use in 131,895 individuals. medRxiv. 2024 Jun 15.
Thorpe HHA, Fontanillas P, Meredith JJ, Jennings MV, Cupertino RB, Pakala S, 23andMe Research Team, Elson SL, Khokhar JY, Davis LK, Johnson EC, Palmer AA, Sanchez-Roige S. PMID: 38947071; PMCID: PMC11213095.
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PubMed Mentions:
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Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations. Neuropsychopharmacology. 2024 Sep; 49(10):1609-1618.
Thorpe HHA, Fontanillas P, Pham BK, Meredith JJ, Jennings MV, Courchesne-Krak NS, Vilar-Ribó L, Bianchi SB, Mutz J, 23andMe Research Team, Elson SL, Khokhar JY, Abdellaoui A, Davis LK, Palmer AA, Sanchez-Roige S. PMID: 38858598; PMCID: PMC11319477.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Genome-wide association study for age-related hearing loss in CFW mice. bioRxiv. 2024 Jun 10.
Polesskaya O, Boussaty E, Cheng R, Lamonte O, Zhou T, Du E, Sanches TM, Nguyen KM, Okamoto M, Palmer AA, Friedman R. PMID: 38915500; PMCID: PMC11195089.
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PubMed Mentions:
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Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics. bioRxiv. 2024 May 15.
Munro D, Ehsan N, Esmaeili-Fard SM, Gusev A, Palmer AA, Mohammadi P. PMID: 38798366; PMCID: PMC11118360.
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PubMed Mentions:
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Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nat Hum Behav. 2024 Jun; 8(6):1177-1193.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik VK, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M, Penn Medicine BioBank, Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. PMID: 38632388; PMCID: PMC11199106.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals. EBioMedicine. 2024 May; 103:105086.
Jennings MV, Martínez-Magaña JJ, Courchesne-Krak NS, Cupertino RB, Vilar-Ribó L, Bianchi SB, Hatoum AS, Atkinson EG, Giusti-Rodriguez P, Montalvo-Ortiz JL, Gelernter J, Artigas MS, 23andMe, Inc. Research Team, Elson SL, Edenberg HJ, Fontanillas P, Palmer AA, Sanchez-Roige S. PMID: 38580523; PMCID: PMC11121167.
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PubMed Mentions: Fields:
Translation:
Humans
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Genomic Loci Influencing Cue-Reactivity in Heterogeneous Stock Rats. bioRxiv. 2024 Apr 03.
King CP, Chitre AS, Leal-Gutiérrez JD, Tripi JA, Hughson AR, Horvath AP, Lamparelli AC, George A, Martin C, Pierre CLS, Sanches T, Bimschleger HV, Gao J, Cheng R, Nguyen KM, Holl KL, Polesskaya O, Ishiwari K, Chen H, Woods LCS, Palmer AA, Robinson TE, Flagel SB, Meyer PJ. PMID: 38559127; PMCID: PMC10980002.
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A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. Cell Genom. 2024 Apr 10; 4(4):100527.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. PMID: 38537634; PMCID: PMC11019364.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Rare and Common Variants Associated with Alcohol Consumption Identify a Conserved Molecular Network. bioRxiv. 2024 Mar 01.
Leger BS, Meredith JJ, Ideker T, Sanchez-Roige S, Palmer AA. PMID: 38464225; PMCID: PMC10925118.
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PubMed Mentions:
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Interaction models matter: an efficient, flexible computational framework for model-specific investigation of epistasis. BioData Min. 2024 Feb 28; 17(1):7.
Batista S, Madar VS, Freda PJ, Bhandary P, Ghosh A, Matsumoto N, Chitre AS, Palmer AA, Moore JH. PMID: 38419006; PMCID: PMC10900690.
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PubMed Mentions:
2
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Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats. Sci Rep. 2024 02 20; 14(1):4182.
Ishiwari K, King CP, Martin CD, Tripi JA, George AM, Lamparelli AC, Chitre AS, Polesskaya O, Richards JB, Solberg Woods LC, Gancarz AM, Palmer AA, Dietz DM, Mitchell SH, Meyer PJ. PMID: 38378969; PMCID: PMC10879139.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Genome-wide association study of delay discounting in Heterogenous Stock rats. bioRxiv. 2023 Dec 13.
Lara MK, Chitre AS, Chen D, Johnson BB, Nguyen KM, Cohen KA, Muckadam SA, Lin B, Ziegler S, Beeson A, Sanches T, Solberg Woods LC, Polesskaya O, Palmer AA, Mitchell SH. PMID: 38168347; PMCID: PMC10760013.
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PubMed Mentions:
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Genome-Wide Association Study of Chronic Dizziness in the Elderly Identifies Loci Implicating MLLT10, BPTF, LINC01224, and ROS1. J Assoc Res Otolaryngol. 2023 Dec; 24(6):575-591.
Clifford R, Munro D, Dochtermann D, Devineni P, Pyarajan S, Million Veteran Program, Telese F, Palmer AA, Mohammadi P, Friedman R. PMID: 38036714; PMCID: PMC10752854.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Y and Mitochondrial Chromosomes in the Heterogeneous Stock Rat Population. bioRxiv. 2023 Nov 29.
Okamoto F, Chitre AS, Missfeldt Sanches T, Chen D, Munro D, NIDA Center for GWAS in Outbred Rats, Polesskaya O, Palmer AA. PMID: 38076923; PMCID: PMC10705385.
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Discovery adductomics provides a comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans. Nucleic Acids Res. 2023 11 10; 51(20):10829-10845.
Guilbaud A, Ghanegolmohammadi F, Wang Y, Leng J, Kreymerman A, Gamboa Varela J, Garbern J, Elwell H, Cao F, Ricci-Blair EM, Liang C, Balamkundu S, Vidoudez C, DeMott MS, Bedi K, Margulies KB, Bennett DA, Palmer AA, Barkley-Levenson A, Lee RT, Dedon PC. PMID: 37843128; PMCID: PMC10639045.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Executive Function and Impulsivity Predict Distinct Genetic Variance in Internalizing Problems, Externalizing Problems, Thought Disorders, and Compulsive Disorders: A Genomic Structural Equation Modeling Study. Clin Psychol Sci. 2024 Sep; 12(5):865-881.
Gustavson DE, Morrison CL, Mallard TT, Jennings MV, Fontanillas P, Elson SL, Palmer AA, Friedman NP, Sanchez-Roige S. PMID: 39323941; PMCID: PMC11423426.
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Author Correction: Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition. Nat Neurosci. 2023 Nov; 26(11):2035.
Zhou JL, de Guglielmo G, Ho AJ, Kallupi M, Pokhrel N, Li HR, Chitre AS, Munro D, Mohammadi P, Carrette LLG, George O, Palmer AA, McVicker G, Telese F. PMID: 37845545; PMCID: PMC10620070.
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PubMed Mentions: Fields:
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Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition. Nat Neurosci. 2023 Nov; 26(11):1868-1879.
Zhou JL, de Guglielmo G, Ho AJ, Kallupi M, Pokhrel N, Li HR, Chitre AS, Munro D, Mohammadi P, Carrette LLG, George O, Palmer AA, McVicker G, Telese F. PMID: 37798411; PMCID: PMC10620093.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. bioRxiv. 2023 Sep 28.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. PMID: 37214860; PMCID: PMC10197727.
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PubMed Mentions:
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Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes. medRxiv. 2023 Sep 18.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M, Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup, Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. PMID: 37034728; PMCID: PMC10081388.
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PubMed Mentions:
1
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Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics. Behav Genet. 2023 11; 53(5-6):404-415.
Williams CM, Poore H, Tanksley PT, Kweon H, Courchesne-Krak NS, Londono-Correa D, Mallard TT, Barr P, Koellinger PD, Waldman ID, Sanchez-Roige S, Harden KP, Palmer AA, Dick DM, Karlsson Linnér R. PMID: 37713023; PMCID: PMC10584908.
View in:
PubMed Mentions:
2 Fields:
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Genome-Wide Association Studies of Coffee Intake in UK/US Participants of European Ancestry Uncover Gene-Cohort Influences. medRxiv. 2023 Sep 11.
Thorpe HHA, Fontanillas P, Pham BK, Meredith JJ, Jennings MV, Courchesne-Krak NS, Vilar-Ribó L, Bianchi SB, Mutz J, 23andMe Research Team, Elson SL, Khokhar JY, Abdellaoui A, Davis LK, Palmer AA, Sanchez-Roige S. PMID: 37745582; PMCID: PMC10516045.
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PubMed Mentions:
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Causal Genetic Loci for a Motivated Behavior Spectrum Harbor Psychiatric Risk Genes. bioRxiv. 2023 Sep 06.
Xu J, Casanave R, Chitre AS, Wang Q, Nguyen KM, Blake C, Wagle M, Cheng R, Polesskaya O, Palmer AA, Guo S. PMID: 37732200; PMCID: PMC10508786.
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PubMed Mentions:
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A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders. Addict Biol. 2023 09; 28(9):e13319.
Poore HE, Hatoum A, Mallard TT, Sanchez-Roige S, Waldman ID, Palmer AA, Harden KP, Barr PB, Dick DM. PMID: 37644899; PMCID: PMC11010459.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats. bioRxiv. 2023 Aug 01.
Ishiwari K, King CP, Martin CD, Tripi JA, George AM, Lamparelli AC, Chitre A, Polesskaya O, Richards JB, Woods LCS, Gancarz A, Palmer AA, Dietz DM, Mitchell SH, Meyer PJ. PMID: 37503161; PMCID: PMC10369912.
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PubMed Mentions:
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Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks. Cell Rep. 2023 08 29; 42(8):112873.
Wright SN, Leger BS, Rosenthal SB, Liu SN, Jia T, Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Garcia Martinez A, George A, Gileta AF, Han W, Netzley AH, King CP, Lamparelli A, Martin C, St Pierre CL, Wang T, Bimschleger H, Richards J, Ishiwari K, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Kreisberg JF, Ideker T, Palmer AA. PMID: 37527041; PMCID: PMC10546330.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Do polygenic indices capture "direct" effects on child externalizing behavior? Within-family analyses in two longitudinal birth cohorts. medRxiv. 2023 Jun 04.
Tanksley PT, Brislin SJ, Wertz J, de Vlaming R, Courchesne-Krak NS, Mallard TT, Raffington LL, Linnér RK, Koellinger P, Palmer A, Sanchez-Roige A, Waldman I, Dick D, Moffitt TE, Caspi A, Harden KP. PMID: 37398155; PMCID: PMC10312898.
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An exponential increase in QTL detection with an increased sample size. Genetics. 2023 05 26; 224(2).
Chitre AS, Polesskaya O, Munro D, Cheng R, Mohammadi P, Holl K, Gao J, Bimschleger H, Martinez AG, George AM, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin CD, St Pierre CL, Tripi JA, Richards JB, Wang T, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Palmer AA. PMID: 36974931; PMCID: PMC10213487.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice. Transl Psychiatry. 2023 05 12; 13(1):167.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T, 23andMe Research Team, Mackillop J, Stephens DN, Elson SL, Fontanillas P, Khokhar JY, Young JW, Palmer AA. PMID: 37173343; PMCID: PMC10182097.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice. Genome Res. 2023 05; 33(5):689-702.
Maksimov MO, Wu C, Ashbrook DG, Villani F, Colonna V, Mousavi N, Ma N, Lu L, Pritchard JK, Goren A, Williams RW, Palmer AA, Gymrek M. PMID: 37127331; PMCID: PMC10317118.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Reward maximization assessed using a sequential patch depletion task in a large sample of heterogeneous stock rats. Sci Rep. 2023 04 29; 13(1):7027.
Gancarz AM, Mitchell SH, George AM, Martin CD, Turk MC, Bool HM, Aktar F, Kwarteng F, Palmer AA, Meyer PJ, Richards JB, Dietz DM, Ishiwari K. PMID: 37120610; PMCID: PMC10148848.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Automated quantitative trait locus analysis (AutoQTL). BioData Min. 2023 Apr 10; 16(1):14.
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre AS, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH. PMID: 37038201; PMCID: PMC10088184.
View in:
PubMed Mentions:
1
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Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics. bioRxiv. 2023 Mar 24.
Williams CM, Poore H, Tanksley PT, Kweon H, Courchesne-Krak NS, Londono-Correa D, Mallard TT, Barr P, Koellinger PD, Waldman ID, Sanchez-Roige S, Harden KP, Palmer AA, Dick DM, Linnér RK. PMID: 36993611; PMCID: PMC10055200.
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PubMed Mentions:
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Shared genetic architecture between attention-deficit/hyperactivity disorder and lifespan. Neuropsychopharmacology. 2023 06; 48(7):981-990.
Vilar-Ribó L, Cabana-Domínguez J, Martorell L, Ramos-Quiroga JA, Sanchez-Roige S, Palmer AA, Vilella E, Ribasés M, Muntané G, Soler Artigas M. PMID: 36906694; PMCID: PMC10209393.
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PubMed Mentions: Fields:
Translation:
Humans
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Reward Maximization Assessed Using a Sequential Patch Depletion Task in a Large Sample of Heterogeneous Stock Rats. Res Sq. 2023 Feb 03.
Gancarz AM, Mitchell SH, George AM, Martin CD, Turk MC, Bool HM, Aktar F, Kwarteng F, Palmer AA, Meyer PJ, Richards JB, Dietz DM, Isiwari K. PMID: 36778344; PMCID: PMC9915773.
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PubMed Mentions:
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Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats. Front Genet. 2022; 13:1029058.
Fowler S, Wang T, Munro D, Kumar A, Chitre AS, Hollingsworth TJ, Garcia Martinez A, St Pierre CL, Bimschleger H, Gao J, Cheng R, Mohammadi P, Chen H, Palmer AA, Polesskaya O, Jablonski MM. PMID: 36793389; PMCID: PMC9922724.
View in:
PubMed Mentions:
4
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Automated quantitative trait locus analysis (AutoQTL). bioRxiv. 2023 Jan 13.
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre A, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH. PMID: 36711526; PMCID: PMC9882220.
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PubMed Mentions:
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Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits. Front Genet. 2022; 13:1003074.
Chitre AS, Hebda-Bauer EK, Blandino P, Bimschleger H, Nguyen KM, Maras P, Li F, Ozel AB, Pan Y, Polesskaya O, Cheng R, Flagel SB, Watson SJ, Li J, Akil H, Palmer AA. PMID: 36712851; PMCID: PMC9873817.
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PubMed Mentions:
10
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Hazardous drinking and alcohol use disorders. Nat Rev Dis Primers. 2022 12 22; 8(1):80.
MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J. PMID: 36550121; PMCID: PMC10284465.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts. Mol Psychiatry. 2022 Nov; 27(11):4633-4641.
Barr PB, Driver MN, Kuo SI, Stephenson M, Aliev F, Linnér RK, Marks J, Anokhin AP, Bucholz K, Chan G, Edenberg HJ, Edwards AC, Francis MW, Hancock DB, Harden KP, Kamarajan C, Kaprio J, Kinreich S, Kramer JR, Kuperman S, Latvala A, Meyers JL, Palmer AA, Plawecki MH, Porjesz B, Rose RJ, Schuckit MA, Salvatore JE, Dick DM. PMID: 36195638; PMCID: PMC9938102.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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The regulatory landscape of multiple brain regions in outbred heterogeneous stock rats. Nucleic Acids Res. 2022 10 28; 50(19):10882-10895.
Munro D, Wang T, Chitre AS, Polesskaya O, Ehsan N, Gao J, Gusev A, Woods LCS, Saba LM, Chen H, Palmer AA, Mohammadi P. PMID: 36263809; PMCID: PMC9638908.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk. Transl Psychiatry. 2022 09 30; 12(1):420.
Barr PB, Mallard TT, Sanchez-Roige S, Poore HE, Linnér RK, COGA Collaborators, Waldman ID, Palmer AA, Harden KP, Dick DM. PMID: 36180423; PMCID: PMC9525649.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Cross-ancestry genomic research: time to close the gap. Neuropsychopharmacology. 2022 09; 47(10):1737-1738.
Atkinson EG, Bianchi SB, Ye GY, Martínez-Magaña JJ, Tietz GE, Montalvo-Ortiz JL, Giusti-Rodriguez P, Palmer AA, Sanchez-Roige S. PMID: 35739257; PMCID: PMC9372026.
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PubMed Mentions:
7 Fields:
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Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities. Cell Genom. 2022 06 08; 2(6).
Mallard TT, Linnér RK, Grotzinger AD, Sanchez-Roige S, Seidlitz J, Okbay A, de Vlaming R, Meddens SFW, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Palmer AA, Davis LK, Tucker-Drob EM, Kendler KS, Keller MC, Koellinger PD, Harden KP. PMID: 35812988; PMCID: PMC9264403.
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PubMed Mentions:
41 Fields:
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Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies. PLoS Genet. 2022 05; 18(5):e1010234.
Gileta AF, Fitzpatrick CJ, Chitre AS, St Pierre CL, Joyce EV, Maguire RJ, McLeod AM, Gonzales NM, Williams AE, Morrow JD, Robinson TE, Flagel SB, Palmer AA. PMID: 35639796; PMCID: PMC9187121.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
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Accelerating Opioid Use Disorders Research by Integrating Multiple Data Modalities. Complex Psychiatry. 2022 Sep; 8(1-2):1-8.
Bianchi SB, Jeffery AD, Samuels DC, Schirle L, Palmer AA, Sanchez-Roige S. PMID: 36545043; PMCID: PMC9669996.
View in:
PubMed Mentions:
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Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction. Front Neurosci. 2022; 16:858427.
Duttke SH, Montilla-Perez P, Chang MW, Li H, Chen H, Carrette LLG, de Guglielmo G, George O, Palmer AA, Benner C, Telese F. PMID: 35651629; PMCID: PMC9149415.
View in:
PubMed Mentions:
11
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A natural mutator allele shapes mutation spectrum variation in mice. Nature. 2022 05; 605(7910):497-502.
Sasani TA, Ashbrook DG, Beichman AC, Lu L, Palmer AA, Williams RW, Pritchard JK, Harris K. PMID: 35545679; PMCID: PMC9272728.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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Genome-wide association mapping of ethanol sensitivity in the Diversity Outbred mouse population. Alcohol Clin Exp Res. 2022 06; 46(6):941-960.
Parker CC, Philip VM, Gatti DM, Kasparek S, Kreuzman AM, Kuffler L, Mansky B, Masneuf S, Sharif K, Sluys E, Taterra D, Taylor WM, Thomas M, Polesskaya O, Palmer AA, Holmes A, Chesler EJ. PMID: 35383961; PMCID: PMC9246903.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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SNPs, short tandem repeats, and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrains. Cell Genom. 2022 Mar 09; 2(3).
Mortazavi M, Ren Y, Saini S, Antaki D, St Pierre CL, Williams A, Sohni A, Wilkinson MF, Gymrek M, Sebat J, Palmer AA. PMID: 35720252; PMCID: PMC9205302.
View in:
PubMed Mentions:
11 Fields:
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Leptin Protects Against the Development and Expression of Cocaine Addiction-Like Behavior in Heterogeneous Stock Rats. Front Behav Neurosci. 2022; 16:832899.
Carrette LLG, Corral C, Boomhower B, Brennan M, Crook C, Ortez C, Shankar K, Simpson S, Maturin L, Solberg Woods LC, Palmer AA, de Guglielmo G, George O. PMID: 35316955; PMCID: PMC8934439.
View in:
PubMed Mentions:
5
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A mutant allele of glycoprotein M6-B (Gpm6b) facilitates behavioral flexibility but increases delay discounting. Genes Brain Behav. 2022 04; 21(4):e12800.
Sanchez-Roige S, Barnes SA, Mallari J, Wood R, Polesskaya O, Palmer AA. PMID: 35243767; PMCID: PMC9211103.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders. Front Psychiatry. 2022; 13:790566.
Gunturkun MH, Wang T, Chitre AS, Garcia Martinez A, Holl K, St Pierre C, Bimschleger H, Gao J, Cheng R, Polesskaya O, Solberg Woods LC, Palmer AA, Chen H. PMID: 35237186; PMCID: PMC8882588.
View in:
PubMed Mentions:
8
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Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries. Genome Biol. 2022 01 13; 23(1):23.
Liang Y, Pividori M, Manichaikul A, Palmer AA, Cox NJ, Wheeler HE, Im HK. PMID: 35027082; PMCID: PMC8759285.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility. G3 (Bethesda). 2022 01 04; 12(1).
Zou J, Gopalakrishnan S, Parker CC, Nicod J, Mott R, Cai N, Lionikas A, Davies RW, Palmer AA, Flint J. PMID: 34791208; PMCID: PMC8728023.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
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Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use. Alcohol Clin Exp Res. 2021 12; 45(12):2485-2494.
Huggett SB, Johnson EC, Hatoum AS, Lai D, Srijeyanthan J, Bubier JA, Chesler EJ, Agrawal A, Palmer AA, Edenberg HJ, Palmer RHC. PMID: 34751961; PMCID: PMC9714312.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry. Mol Psychiatry. 2021 11; 26(11):6209-6217.
Sanchez-Roige S, Fontanillas P, Jennings MV, Bianchi SB, Huang Y, Hatoum AS, Sealock J, Davis LK, Elson SL, 23andMe Research Team, Palmer AA. PMID: 34728798; PMCID: PMC8562028.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
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Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nat Neurosci. 2021 10; 24(10):1367-1376.
Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S, COGA Collaborators, Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM. PMID: 34446935; PMCID: PMC8484054.
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PubMed Mentions:
123 Fields:
Translation:
Humans
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Dissecting indirect genetic effects from peers in laboratory mice. Genome Biol. 2021 07 26; 22(1):216.
Baud A, Casale FP, Barkley-Levenson AM, Farhadi N, Montillot C, Yalcin B, Nicod J, Palmer AA, Stegle O. PMID: 34311762; PMCID: PMC8311926.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Functional validation of a finding from a mouse genome-wide association study shows that Azi2 influences the acute locomotor stimulant response to methamphetamine. Genes Brain Behav. 2021 09; 20(7):e12760.
Zhou X, Barkley-Levenson AM, Montilla-Perez P, Telese F, Palmer AA. PMID: 34173327.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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The Cocaine and Oxycodone Biobanks, Two Repositories from Genetically Diverse and Behaviorally Characterized Rats for the Study of Addiction. eNeuro. 2021 May-Jun; 8(3).
Carrette LLG, de Guglielmo G, Kallupi M, Maturin L, Brennan M, Boomhower B, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Velarde N, Martinez AR, Kononoff J, Kimbrough A, Simpson S, Smith LC, Shankar K, Ramirez FJ, Chitre AS, Lin B, Polesskaya O, Solberg Woods LC, Palmer AA, George O. PMID: 33875455; PMCID: PMC8213442.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use. Behav Genet. 2021 09; 51(5):543-558.
Kuo SI, Salvatore JE, Barr PB, Aliev F, Anokhin A, Bucholz KK, Chan G, Edenberg HJ, Hesselbrock V, Kamarajan C, Kramer JR, Lai D, Mallard TT, Nurnberger JI, Pandey G, Plawecki MH, Sanchez-Roige S, Waldman I, Palmer AA, Externalizing Consortium, Dick DM. PMID: 34117972; PMCID: PMC8403154.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. Am J Psychiatry. 2022 Jan; 179(1):58-70.
Mallard TT, Savage JE, Johnson EC, Huang Y, Edwards AC, Hottenga JJ, Grotzinger AD, Gustavson DE, Jennings MV, Anokhin A, Dick DM, Edenberg HJ, Kramer JR, Lai D, Meyers JL, Pandey AK, Harden KP, Nivard MG, de Geus EJC, Boomsma DI, Agrawal A, Davis LK, Clarke TK, Palmer AA, Sanchez-Roige S. PMID: 33985350; PMCID: PMC9272895.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Integration of evidence across human and model organism studies: A meeting report. Genes Brain Behav. 2021 Apr 23; e12738.
Palmer RHC, Johnson EC, Won H, Polimanti R, Kapoor M, Chitre A, Bogue MA, Benca-Bachman CE, Parker CC, Verma A, Reynolds T, Ernst J, Bray M, Kwon SB, Lai D, Quach BC, Gaddis NC, Saba L, Chen H, Hawrylycz M, Zhang S, Zhou Y, Mahaffey S, Fischer C, Sanchez-Roige S, Bandrowski A, Lu Q, Shen L, Philip V, Gelernter J, Bierut LJ, Hancock DB, Edenberg HJ, Johnson EO, Nestler EJ, Barr PB, Prins P, Smith DJ, Akbarian S, Thorgeirsson T, Walton D, Baker E, Jacobson D, Palmer AA, Miles M, Chesler EJ, Emerson J, Agrawal A, Martone M, Williams RW. PMID: 33893716; PMCID: PMC8365690.
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PubMed Mentions:
8 Fields:
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Sensitivity to food and cocaine cues are independent traits in a large sample of heterogeneous stock rats. Sci Rep. 2021 01 26; 11(1):2223.
King CP, Tripi JA, Hughson AR, Horvath AP, Lamparelli AC, Holl KL, Chitre AS, Polesskaya O, Ishiwari K, Solberg Woods LC, Palmer AA, Robinson TE, Flagel SB, Meyer PJ. PMID: 33500444; PMCID: PMC7838206.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Genetic and Pharmacological Manipulations of Glyoxalase 1 Mediate Ethanol Withdrawal Seizure Susceptibility in Mice. Brain Sci. 2021 Jan 19; 11(1).
Barkley-Levenson AM, Lee A, Palmer AA. PMID: 33478138; PMCID: PMC7835754.
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PubMed Mentions:
1
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Correction: ACNP efforts toward reducing climate change. Neuropsychopharmacology. 2020 Dec; 45(13):2301.
Jordan CJ, Palmer AA. PMID: 32884099; PMCID: PMC7784678.
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PubMed Mentions: Fields:
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Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis". PLoS Genet. 2020 10; 16(10):e1009165.
Rau CD, Gonzales NM, Bloom JS, Park D, Ayroles J, Palmer AA, Lusis AJ, Zaitlen N. PMID: 33104702; PMCID: PMC7644088.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research. Genetics. 2020 12; 216(4):905-930.
Sigmon JS, Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, Gershon TR, Gralinski L, Gu B, Gaines CH, Hagan RS, Heimsath EG, Heise MT, Hock P, Ideraabdullah F, Jennette JC, Kafri T, Kashfeen A, Kulis M, Kumar V, Linnertz C, Livraghi-Butrico A, Lloyd KCK, Lutz C, Lynch RM, Magnuson T, Matsushima GK, McMullan R, Miller DR, Mohlke KL, Moy SS, Murphy CEY, Najarian M, O'Brien L, Palmer AA, Philpot BD, Randell SH, Reinholdt L, Ren Y, Rockwood S, Rogala AR, Saraswatula A, Sassetti CM, Schisler JC, Schoenrock SA, Shaw GD, Shorter JR, Smith CM, St Pierre CL, Tarantino LM, Threadgill DW, Valdar W, Vilen BJ, Wardwell K, Whitmire JK, Williams L, Zylka MJ, Ferris MT, McMillan L, Manuel de Villena FP. PMID: 33067325; PMCID: PMC7768238.
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PubMed Mentions:
43 Fields:
Translation:
Animals
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Virtual meetings: A critical step to address climate change. Sci Adv. 2020 Sep; 6(38).
Jordan CJ, Palmer AA. PMID: 32938670; PMCID: PMC7494333.
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PubMed Mentions:
3 Fields:
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Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose. Obesity (Silver Spring). 2020 10; 28(10):1964-1973.
Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Bimschleger H, Garcia Martinez A, George T, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin C, St Pierre CL, Tripi JA, Wang T, Chen H, Flagel SB, Meyer P, Richards J, Robinson TE, Palmer AA, Solberg Woods LC. PMID: 32860487; PMCID: PMC7511439.
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PubMed Mentions:
42 Fields:
Translation:
Animals
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ACNP efforts toward reducing climate change. Neuropsychopharmacology. 2020 12; 45(13):2137-2138.
Jordan CJ, Palmer AA. PMID: 32791512; PMCID: PMC7441834.
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PubMed Mentions: Fields:
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The Latent Genetic Structure of Impulsivity and Its Relation to Internalizing Psychopathology. Psychol Sci. 2020 08; 31(8):1025-1035.
Gustavson DE, Friedman NP, Fontanillas P, Elson SL, 23andMe Research Team, Palmer AA, Sanchez-Roige S. PMID: 32716714; PMCID: PMC7427138.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Adapting Genotyping-by-Sequencing and Variant Calling for Heterogeneous Stock Rats. G3 (Bethesda). 2020 07 07; 10(7):2195-2205.
Gileta AF, Gao J, Chitre AS, Bimschleger HV, St Pierre CL, Gopalakrishnan S, Palmer AA. PMID: 32398234; PMCID: PMC7341140.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Nat Neurosci. 2020 07; 23(7):809-818.
Zhou H, Sealock JM, Sanchez-Roige S, Clarke TK, Levey DF, Cheng Z, Li B, Polimanti R, Kember RL, Smith RV, Thygesen JH, Morgan MY, Atkinson SR, Thursz MR, Nyegaard M, Mattheisen M, Børglum AD, Johnson EC, Justice AC, Palmer AA, McQuillin A, Davis LK, Edenberg HJ, Agrawal A, Kranzler HR, Gelernter J. PMID: 32451486; PMCID: PMC7485556.
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PubMed Mentions:
169 Fields:
Translation:
Humans
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Sex-dependent associations between addiction-related behaviors and the microbiome in outbred rats. EBioMedicine. 2020 May; 55:102769.
Peterson VL, Richards JB, Meyer PJ, Cabrera-Rubio R, Tripi JA, King CP, Polesskaya O, Baud A, Chitre AS, Bastiaanssen TFS, Woods LS, Crispie F, Dinan TG, Cotter PD, Palmer AA, Cryan JF. PMID: 32403084; PMCID: PMC7218262.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Emerging phenotyping strategies will advance our understanding of psychiatric genetics. Nat Neurosci. 2020 04; 23(4):475-480.
Sanchez-Roige S, Palmer AA. PMID: 32231337; PMCID: PMC9200410.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Genome-Wide Association Study in Two Cohorts from a Multi-generational Mouse Advanced Intercross Line Highlights the Difficulty of Replication Due to Study-Specific Heterogeneity. G3 (Bethesda). 2020 03 05; 10(3):951-965.
Zhou X, St Pierre CL, Gonzales NM, Zou J, Cheng R, Chitre AS, Sokoloff G, Palmer AA. PMID: 31974095; PMCID: PMC7056977.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
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Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addict Biol. 2021 01; 26(1):e12880.
Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Landén M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gäebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, et al. PMID: 32064741; PMCID: PMC7429266.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Multidimensional latent structure of risk-related phenotypes in healthy young adults. Exp Clin Psychopharmacol. 2020 Feb; 28(1):55-64.
Pabon E, MacKillop J, Palmer AA, de Wit H. PMID: 30998058; PMCID: PMC7233128.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples. Psychol Med. 2021 05; 51(7):1147-1156.
Johnson EC, Sanchez-Roige S, Acion L, Adams MJ, Bucholz KK, Chan G, Chao MJ, Chorlian DB, Dick DM, Edenberg HJ, Foroud T, Hayward C, Heron J, Hesselbrock V, Hickman M, Kendler KS, Kinreich S, Kramer J, Kuo SI, Kuperman S, Lai D, McIntosh AM, Meyers JL, Plawecki MH, Porjesz B, Porteous D, Schuckit MA, Su J, Zang Y, Palmer AA, Agrawal A, Clarke TK, Edwards AC. PMID: 31955720; PMCID: PMC7405725.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2140-2148.
Kallupi M, Carrette LLG, Kononoff J, Solberg Woods LC, Palmer AA, Schweitzer P, George O, de Guglielmo G. PMID: 31932450; PMCID: PMC6994987.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. Am J Hum Genet. 2020 Jan 02; 106(1):138.
Hernandez Cordero AI, Gonzales NM, Parker CC, Sokoloff G, Vandenbergh DJ, Cheng R, Abney M, Skol A, Douglas A, Palmer AA, Gregory JS, Lionikas A. PMID: 31901248; PMCID: PMC7042490.
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PubMed Mentions:
2 Fields:
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Steep Discounting of Future Rewards as an Impulsivity Phenotype: A Concise Review. Curr Top Behav Neurosci. 2020; 47:113-138.
Levitt E, Sanchez-Roige S, Palmer AA, MacKillop J. PMID: 32236897.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Assessing the motivational effects of ethanol in mice using a discrete-trial current-intensity intracranial self-stimulation procedure. Drug Alcohol Depend. 2020 02 01; 207:107806.
Barkley-Levenson AM, Der-Avakian A, Palmer AA. PMID: 31864164; PMCID: PMC6939988.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease. Mol Psychiatry. 2021 08; 26(8):4254-4264.
Dennis J, Sealock J, Levinson RT, Farber-Eger E, Franco J, Fong S, Straub P, Hucks D, Song WL, Linton MF, Fontanillas P, Elson SL, Ruderfer D, Abdellaoui A, Sanchez-Roige S, Palmer AA, Boomsma DI, Cox NJ, Chen G, Mosley JD, Wells QS, Davis LK. PMID: 31796895; PMCID: PMC7266730.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. Am J Hum Genet. 2019 12 05; 105(6):1222-1236.
Hernandez Cordero AI, Gonzales NM, Parker CC, Sokolof G, Vandenbergh DJ, Cheng R, Abney M, Sko A, Douglas A, Palmer AA, Gregory JS, Lionikas A. PMID: 31761296; PMCID: PMC6904802.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness. Hum Mol Genet. 2019 11 15; 28(22):3853-3865.
Abdellaoui A, Sanchez-Roige S, Sealock J, Treur JL, Dennis J, Fontanillas P, Elson S, 23andme Research Team, Nivard MG, Ip HF, van der Zee M, Baselmans BML, Hottenga JJ, Willemsen G, Mosing M, Lu Y, Pedersen NL, Denys D, Amin N, M van Duijn C, Szilagyi I, Tiemeier H, Neumann A, Verweij KJH, Cacioppo S, Cacioppo JT, Davis LK, Palmer AA, Boomsma DI. PMID: 31518406; PMCID: PMC6935385.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Recent Efforts to Dissect the Genetic Basis of Alcohol Use and Abuse. Biol Psychiatry. 2020 04 01; 87(7):609-618.
Sanchez-Roige S, Palmer AA, Clarke TK. PMID: 31733789; PMCID: PMC7071963.
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PubMed Mentions:
40 Fields:
Translation:
Humans
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Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability. Nat Neurosci. 2019 Jul; 22(7):1196.
Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Mägi R, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Paus T, Ribases M, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Munafò MR, Gillespie NA, Derks EM, Vink JM. PMID: 31168101.
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PubMed Mentions:
4 Fields:
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Genomic basis of delayed reward discounting. Behav Processes. 2019 May; 162:157-161.
Gray JC, Sanchez-Roige S, de Wit H, MacKillop J, Palmer AA. PMID: 30876880; PMCID: PMC6980721.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2019 Mar; 22(3):503.
Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Abecasis GR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. PMID: 30622366.
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PubMed Mentions: Fields:
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Electronic Health Records Are the Next Frontier for the Genetics of Substance Use Disorders. Trends Genet. 2019 05; 35(5):317-318.
Sanchez-Roige S, Palmer AA. PMID: 30797598; PMCID: PMC6984003.
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PubMed Mentions:
6 Fields:
Translation:
HumansPHPublic Health
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Incentive salience attribution, "sensation-seeking" and "novelty-seeking" are independent traits in a large sample of male and female heterogeneous stock rats. Sci Rep. 2019 02 20; 9(1):2351.
Hughson AR, Horvath AP, Holl K, Palmer AA, Solberg Woods LC, Robinson TE, Flagel SB. PMID: 30787409; PMCID: PMC6382850.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Genome-Wide Association Studies of Impulsive Personality Traits (BIS-11 and UPPS-P) and Drug Experimentation in up to 22,861 Adult Research Participants Identify Loci in the CACNA1I and CADM2 genes. J Neurosci. 2019 03 27; 39(13):2562-2572.
Sanchez-Roige S, Fontanillas P, Elson SL, Gray JC, de Wit H, MacKillop J, Palmer AA. PMID: 30718321; PMCID: PMC6435820.
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PubMed Mentions:
67 Fields:
Translation:
Humans
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Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. J Med Chem. 2019 02 14; 62(3):1609-1625.
Perez C, Barkley-Levenson AM, Dick BL, Glatt PF, Martinez Y, Siegel D, Momper JD, Palmer AA, Cohen SM. PMID: 30628789; PMCID: PMC6467756.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nat Genet. 2019 02; 51(2):245-257.
Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntané G, Sanchez-Roige S, Rooij FJV, Taskesen E, Wu Y, Zhang F, 23and Me Research Team, eQTLgen Consortium, International Cannabis Consortium, Social Science Genetic Association Consortium, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram MA, Jain S, Karlsson R, Kessler RC, Kooyman M, MacKillop J, Männikkö M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, Wit H, Yang J, Bertram L, Boomsma DI, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger PD, Beauchamp JP. PMID: 30643258; PMCID: PMC6713272.
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PubMed Mentions:
295 Fields:
Translation:
Humans
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Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits. Methods Mol Biol. 2019; 2018:233-247.
Solberg Woods LC, Palmer AA. PMID: 31228160; PMCID: PMC9121584.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Behavioral Genetic Studies in Rats. Methods Mol Biol. 2019; 2018:319-326.
Ren Y, Palmer AA. PMID: 31228165.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Social and anxiety-like behaviors contribute to nicotine self-administration in adolescent outbred rats. Sci Rep. 2018 12 24; 8(1):18069.
Wang T, Han W, Chitre AS, Polesskaya O, Solberg Woods LC, Palmer AA, Chen H. PMID: 30584246; PMCID: PMC6305389.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Genome wide association analysis in a mouse advanced intercross line. Nat Commun. 2018 12 04; 9(1):5162.
Gonzales NM, Seo J, Hernandez Cordero AI, St Pierre CL, Gregory JS, Distler MG, Abney M, Canzar S, Lionikas A, Palmer AA. PMID: 30514929; PMCID: PMC6279738.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 12; 21(12):1656-1669.
Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A. PMID: 30482948; PMCID: PMC6430207.
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PubMed Mentions:
318 Fields:
Translation:
Humans
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Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. Am J Psychiatry. 2019 02 01; 176(2):107-118.
Sanchez-Roige S, Palmer AA, Fontanillas P, Elson SL, 23andMe Research Team, the Substance Use Disorder Working Group of the Psychiatric Genomics Consorti, Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary IJ, McIntosh AM, Clarke TK. PMID: 30336701; PMCID: PMC6365681.
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PubMed Mentions:
196 Fields:
Translation:
Humans
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Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach. Exp Clin Psychopharmacol. 2019 Feb; 27(1):29-37.
MacKillop J, Gray JC, Weafer J, Sanchez-Roige S, Palmer AA, de Wit H. PMID: 30265060; PMCID: PMC6908809.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Nat Neurosci. 2018 09; 21(9):1161-1170.
Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Mägi R, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Paus T, Ribases M, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Munafò MR, Gillespie NA, Derks EM, Vink JM. PMID: 30150663; PMCID: PMC6386176.
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PubMed Mentions:
215 Fields:
Translation:
Humans
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Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 Jul; 21(7):1018.
Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Abecasis GR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. PMID: 29752479.
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PubMed Mentions: Fields:
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Glyoxalase 1 (GLO1) Inhibition or Genetic Overexpression Does Not Alter Ethanol's Locomotor Effects: Implications for GLO1 as a Therapeutic Target in Alcohol Use Disorders. Alcohol Clin Exp Res. 2018 05; 42(5):869-878.
Barkley-Levenson AM, Lagarda FA, Palmer AA. PMID: 29532486; PMCID: PMC5915917.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Inhibition of Glyoxalase 1 reduces alcohol self-administration in dependent and nondependent rats. Pharmacol Biochem Behav. 2018 04; 167:36-41.
de Guglielmo G, Conlisk DE, Barkley-Levenson AM, Palmer AA, George O. PMID: 29505808; PMCID: PMC5866249.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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The genetics of human personality. Genes Brain Behav. 2018 03; 17(3):e12439.
Sanchez-Roige S, Gray JC, MacKillop J, Chen CH, Palmer AA. PMID: 29152902; PMCID: PMC7012279.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 01; 21(1):16-18.
Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Abecasis GR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. PMID: 29230059; PMCID: PMC6984001.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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Hierarchical investigation of genetic influences on response inhibition in healthy young adults. Exp Clin Psychopharmacol. 2017 12; 25(6):512-520.
Weafer J, Gray JC, Hernandez K, Palmer AA, MacKillop J, de Wit H. PMID: 29251981; PMCID: PMC5737791.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation. Psychiatry Res. 2018 01; 259:398-404.
Gray JC, MacKillop J, Weafer J, Hernandez KM, Gao J, Palmer AA, de Wit H. PMID: 29120849; PMCID: PMC5742029.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry. Addict Biol. 2019 01; 24(1):121-131.
Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. PMID: 29058377; PMCID: PMC6988186.
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PubMed Mentions:
57 Fields:
Translation:
HumansPHPublic Health
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Heterogeneous stock rats: a model to study the genetics of despair-like behavior in adolescence. Genes Brain Behav. 2018 02; 17(2):139-148.
Holl K, He H, Wedemeyer M, Clopton L, Wert S, Meckes JK, Cheng R, Kastner A, Palmer AA, Redei EE, Solberg Woods LC. PMID: 28834208; PMCID: PMC5836722.
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PubMed Mentions:
17 Fields:
Translation:
Animals
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Impulsivity as a mechanism linking child abuse and neglect with substance use in adolescence and adulthood. Dev Psychopathol. 2018 05; 30(2):417-435.
Oshri A, Kogan SM, Kwon JA, Wickrama KAS, Vanderbroek L, Palmer AA, MacKillop J. PMID: 28606210.
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PubMed Mentions:
48 Translation:
Humans
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Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):458-466.
Bidwell LC, Gray JC, Weafer J, Palmer AA, de Wit H, MacKillop J. PMID: 28512748; PMCID: PMC5690554.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning. Genes Brain Behav. 2017 09; 16(7):686-698.
King CP, Militello L, Hart A, St Pierre CL, Leung E, Versaggi CL, Roberson N, Catlin J, Palmer AA, Richards JB, Meyer PJ. PMID: 28387990; PMCID: PMC5595635.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Identification of a novel, fast-acting GABAergic antidepressant. Mol Psychiatry. 2018 02; 23(2):384-391.
McMurray KMJ, Ramaker MJ, Barkley-Levenson AM, Sidhu PS, Elkin PK, Reddy MK, Guthrie ML, Cook JM, Rawal VH, Arnold LA, Dulawa SC, Palmer AA. PMID: 28322281; PMCID: PMC5608625.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Fine-mapping of genes determining extrafusal fiber properties in murine soleus muscle. Physiol Genomics. 2017 03 01; 49(3):141-150.
Carroll AM, Cheng R, Collie-Duguid ES, Meharg C, Scholz ME, Fiering S, Fields JL, Palmer AA, Lionikas A. PMID: 28087756; PMCID: PMC5374456.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Sex-specific linkage scans in opioid dependence. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 174(3):261-268.
Yang BZ, Han S, Kranzler HR, Palmer AA, Gelernter J. PMID: 27762075; PMCID: PMC5695218.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Syntax for calculation of discounting indices from the monetary choice questionnaire and probability discounting questionnaire. J Exp Anal Behav. 2016 09; 106(2):156-63.
Gray JC, Amlung MT, Palmer AA, MacKillop J. PMID: 27644448; PMCID: PMC5042866.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Neuropsychopharmacology. 2017 Mar; 42(4):811-821.
Gao J, Davis LK, Hart AB, Sanchez-Roige S, Han L, Cacioppo JT, Palmer AA. PMID: 27629369; PMCID: PMC5312064.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Genetic Background Limits Generalizability of Genotype-Phenotype Relationships. Neuron. 2016 Sep 21; 91(6):1253-1259.
Sittig LJ, Carbonetto P, Engel KA, Krauss KS, Barrios-Camacho CM, Palmer AA. PMID: 27618673; PMCID: PMC5033712.
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PubMed Mentions:
128 Fields:
Translation:
Animals
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The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits. Psychopharmacology (Berl). 2016 Sep; 233(18):3361-70.
MacKillop J, Weafer J, C Gray J, Oshri A, Palmer A, de Wit H. PMID: 27449350; PMCID: PMC5204128.
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PubMed Mentions:
145 Fields:
Translation:
Humans
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Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet. 2016 08; 48(8):919-26.
Parker CC, Gopalakrishnan S, Carbonetto P, Gonzales NM, Leung E, Park YJ, Aryee E, Davis J, Blizard DA, Ackert-Bicknell CL, Lionikas A, Pritchard JK, Palmer AA. PMID: 27376237; PMCID: PMC4963286.
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PubMed Mentions:
54 Fields:
Translation:
Animals
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Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes Brain Behav. 2016 07; 15(6):604-15.
Young EE, Bryant CD, Lee SE, Peng X, Cook B, Nair HK, Dreher KJ, Zhang X, Palmer AA, Chung JM, Mogil JS, Chesler EJ, Lariviere WR. PMID: 27231153; PMCID: PMC4955286.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Premature responding is associated with approach to a food cue in male and female heterogeneous stock rats. Psychopharmacology (Berl). 2016 07; 233(13):2593-605.
King CP, Palmer AA, Woods LC, Hawk LW, Richards JB, Meyer PJ. PMID: 27146401; PMCID: PMC5025873.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Individual differences in timing of peak positive subjective responses to d-amphetamine: Relationship to pharmacokinetics and physiology. J Psychopharmacol. 2016 Apr; 30(4):330-43.
Smith CT, Weafer J, Cowan RL, Kessler RM, Palmer AA, de Wit H, Zald DH. PMID: 26880226; PMCID: PMC5049703.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Integration of genome-wide association and extant brain expression QTL identifies candidate genes influencing prepulse inhibition in inbred F1 mice. Genes Brain Behav. 2016 Feb; 15(2):260-70.
Sittig LJ, Carbonetto P, Engel KA, Krauss KS, Palmer AA. PMID: 26482417; PMCID: PMC4873164.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice. Addict Biol. 2017 Mar; 22(2):381-389.
McMurray KM, Sidhu PS, Cook JM, Arnold LA, Palmer AA. PMID: 26691867; PMCID: PMC4917470.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice. Behav Brain Res. 2016 Mar 15; 301:119-23.
McMurray KM, Du X, Brownlee M, Palmer AA. PMID: 26711908; PMCID: PMC4728018.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet. 2015 Dec; 11(12):e1005713.
Yazdani N, Parker CC, Shen Y, Reed ER, Guido MA, Kole LA, Kirkpatrick SL, Lim JE, Sokoloff G, Cheng R, Johnson WE, Palmer AA, Bryant CD. PMID: 26658939; PMCID: PMC4675533.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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A dendritic organization of lateral amygdala neurons in fear susceptible and resistant mice. Neurobiol Learn Mem. 2016 Jan; 127:64-71.
Castro-Gomes V, Bergstrom HC, McGuire JL, Parker CC, Coyner J, Landeira-Fernandez J, Ursano RJ, Palmer AA, Johnson LR. PMID: 26642919.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination. PLoS Genet. 2015 Nov; 11(11):e1005607.
Pallares LF, Carbonetto P, Gopalakrishnan S, Parker CC, Ackert-Bicknell CL, Palmer AA, Tautz D. PMID: 26523602; PMCID: PMC4629907.
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PubMed Mentions:
38 Fields:
Translation:
Animals
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Interrelationships among parental family history of substance misuse, delay discounting, and personal substance use. Psychopharmacology (Berl). 2016 Jan; 233(1):39-48.
VanderBroek L, Acker J, Palmer AA, de Wit H, MacKillop J. PMID: 26395990; PMCID: PMC4830143.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behav Genet. 2016 Mar; 46(2):170-82.
van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppälä I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Eriksson JG, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Lehtimäki T, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Pulkki-Råback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Generation Scotland, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Räikkönen K, Wilson JF, Keltikangas-Järvinen L, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Martin NG, Boomsma DI. PMID: 26362575; PMCID: PMC4751159.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry. 2015 Jul; 72(7):642-50.
Genetics of Personality Consortium, de Moor MH, van den Berg SM, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppälä I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Davey Smith G, Davies G, de Wit H, Ding J, Engelhardt BE, Eriksson JG, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Lehtimäki T, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Pulkki-Råback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Räikkönen K, Wilson JF, Keltikangas-Järvinen L, Bierut LJ, Hettema JM, Grabe HJ, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Penninx BW, Martin NG, Boomsma DI. PMID: 25993607; PMCID: PMC4667957.
View in:
PubMed Mentions:
119 Fields:
Translation:
Humans
-
Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda). 2014 Sep 18; 4(9):1623-33.
Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. PMID: 25237114; PMCID: PMC4169154.
View in:
PubMed Mentions:
139 Fields:
Translation:
AnimalsCells
-
High-resolution genetic mapping of complex traits from a combined analysis of F2 and advanced intercross mice. Genetics. 2014 Sep; 198(1):103-16.
Parker CC, Carbonetto P, Sokoloff G, Park YJ, Abney M, Palmer AA. PMID: 25236452; PMCID: PMC4174923.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Phenotypic instability between the near isogenic substrains BALB/cJ and BALB/cByJ. Mamm Genome. 2014 Dec; 25(11-12):564-72.
Sittig LJ, Jeong C, Tixier E, Davis J, Barrios-Camacho CM, Palmer AA. PMID: 24997021; PMCID: PMC4241159.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice. Physiol Genomics. 2014 Aug 15; 46(16):571-82.
Carbonetto P, Cheng R, Gyekis JP, Parker CC, Blizard DA, Palmer AA, Lionikas A. PMID: 24963006; PMCID: PMC4137148.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Fine-mapping QTLs in advanced intercross lines and other outbred populations. Mamm Genome. 2014 Aug; 25(7-8):271-92.
Gonzales NM, Palmer AA. PMID: 24906874; PMCID: PMC4126234.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Social neuroscience and its potential contribution to psychiatry. World Psychiatry. 2014 Jun; 13(2):131-9.
Cacioppo JT, Cacioppo S, Dulawa S, Palmer AA. PMID: 24890058; PMCID: PMC4102278.
View in:
PubMed Mentions:
22
-
Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):6004-9.
Swaggart KA, Demonbreun AR, Vo AH, Swanson KE, Kim EY, Fahrenbach JP, Holley-Cuthrell J, Eskin A, Chen Z, Squire K, Heydemann A, Palmer AA, Nelson SF, McNally EM. PMID: 24717843; PMCID: PMC4000833.
View in:
PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
-
Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5968-73.
Hart AB, Gamazon ER, Engelhardt BE, Sklar P, Kähler AK, Hultman CM, Sullivan PF, Neale BM, Faraone SV, Psychiatric Genomics Consortium: ADHD Subgroup, de Wit H, Cox NJ, Palmer AA. PMID: 24711425; PMCID: PMC4000861.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development. Biochem Soc Trans. 2014 Apr; 42(2):461-7.
McMurray KM, Distler MG, Sidhu PS, Cook JM, Arnold LA, Palmer AA, Plant LD. PMID: 24646261; PMCID: PMC4036232.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice. Sleep. 2014 Apr 01; 37(4):785-93, 793A-793C.
Zhou L, Bryant CD, Loudon A, Palmer AA, Vitaterna MH, Turek FW. PMID: 24744456; PMCID: PMC3972422.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis. Genes Brain Behav. 2014 Mar; 13(3):341-9.
Winawer MR, Klassen TL, Teed S, Shipman M, Leung EH, Palmer AA. PMID: 24373497; PMCID: PMC3947448.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Propensity for social interaction predicts nicotine-reinforced behaviors in outbred rats. Genes Brain Behav. 2014 Feb; 13(2):202-12.
Wang T, Han W, Wang B, Jiang Q, Solberg-Woods LC, Palmer AA, Chen H. PMID: 24289793; PMCID: PMC3934210.
View in:
PubMed Mentions:
24 Fields:
Translation:
Animals
-
Genetic variation for life history sensitivity to seasonal warming in Arabidopsis thaliana. Genetics. 2014 Feb; 196(2):569-77.
Li Y, Cheng R, Spokas KA, Palmer AA, Borevitz JO. PMID: 24281156; PMCID: PMC3914627.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Practical considerations regarding the use of genotype and pedigree data to model relatedness in the context of genome-wide association studies. G3 (Bethesda). 2013 Oct 03; 3(10):1861-7.
Cheng R, Parker CC, Abney M, Palmer AA. PMID: 23979941; PMCID: PMC3789811.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
-
Variation in the form of Pavlovian conditioned approach behavior among outbred male Sprague-Dawley rats from different vendors and colonies: sign-tracking vs. goal-tracking. PLoS One. 2013; 8(10):e75042.
Fitzpatrick CJ, Gopalakrishnan S, Cogan ES, Yager LM, Meyer PJ, Lovic V, Saunders BT, Parker CC, Gonzales NM, Aryee E, Flagel SB, Palmer AA, Robinson TE, Morrow JD. PMID: 24098363; PMCID: PMC3787975.
View in:
PubMed Mentions:
70 Fields:
Translation:
Animals
-
Traits of fear resistance and susceptibility in an advanced intercross line. Eur J Neurosci. 2013 Nov; 38(9):3314-24.
McGuire JL, Bergstrom HC, Parker CC, Le T, Morgan M, Tang H, Selwyn RG, Silva AC, Choi K, Ursano RJ, Palmer AA, Johnson LR. PMID: 23968228; PMCID: PMC5581004.
View in:
PubMed Mentions:
10 Translation:
Animals
-
A large QTL for fear and anxiety mapped using an F2 cross can be dissected into multiple smaller QTLs. Genes Brain Behav. 2013 Oct; 12(7):714-22.
Parker CC, Sokoloff G, Leung E, Kirkpatrick SL, Palmer AA. PMID: 23876074; PMCID: PMC3947048.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Mice selectively bred for High and Low fear behavior show differences in the number of pMAPK (p44/42 ERK) expressing neurons in lateral amygdala following Pavlovian fear conditioning. Neurobiol Learn Mem. 2014 Jul; 112:195-203.
Coyner J, McGuire JL, Parker CC, Ursano RJ, Palmer AA, Johnson LR. PMID: 23811025.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Strong genetic influences on measures of behavioral-regulation among inbred rat strains. Genes Brain Behav. 2013 Jul; 12(5):490-502.
Richards JB, Lloyd DR, Kuehlewind B, Militello L, Paredez M, Solberg Woods L, Palmer AA. PMID: 23710681; PMCID: PMC4425401.
View in:
PubMed Mentions:
29 Fields:
Translation:
Animals
-
Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Neuropharmacology. 2014 Jan; 76 Pt B:250-8.
Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA. PMID: 23791960; PMCID: PMC3823679.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
-
Psychopharmacology of theobromine in healthy volunteers. Psychopharmacology (Berl). 2013 Jul; 228(1):109-18.
Baggott MJ, Childs E, Hart AB, de Bruin E, Palmer AA, Wilkinson JE, de Wit H. PMID: 23420115; PMCID: PMC3672386.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. Epilepsia. 2013 Apr; 54(4):649-57.
Distler MG, Gorfinkle N, Papale LA, Wuenschell GE, Termini J, Escayg A, Winawer MR, Palmer AA. PMID: 23409935; PMCID: PMC3618549.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Does COMT genotype influence the effects of d-amphetamine on executive functioning? Genes Brain Behav. 2013 Feb; 12(1):13-20.
Wardle MC, Hart AB, Palmer AA, de Wit H. PMID: 23231539; PMCID: PMC3553317.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
A simulation study of permutation, bootstrap, and gene dropping for assessing statistical significance in the case of unequal relatedness. Genetics. 2013 Mar; 193(3):1015-8.
Cheng R, Palmer AA. PMID: 23267053; PMCID: PMC3583989.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Assessment of behaviors modeling aspects of schizophrenia in Csmd1 mutant mice. PLoS One. 2012; 7(12):e51235.
Distler MG, Opal MD, Dulawa SC, Palmer AA. PMID: 23284669; PMCID: PMC3524225.
View in:
PubMed Mentions:
14 Fields:
Translation:
Animals
-
Candidate gene studies of a promising intermediate phenotype: failure to replicate. Neuropsychopharmacology. 2013 Apr; 38(5):802-16.
Hart AB, de Wit H, Palmer AA. PMID: 23303064; PMCID: PMC3671998.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCellsCTClinical Trials
-
Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights. Front Genet. 2012; 3:250.
Distler MG, Palmer AA. PMID: 23181072; PMCID: PMC3500958.
View in:
PubMed Mentions:
47
-
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One. 2012; 7(8):e42646.
Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H, Palmer AA. PMID: 22952603; PMCID: PMC3429486.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Methamphetamine-induced conditioned place preference in LG/J and SM/J mouse strains and an F45/F46 advanced intercross line. Front Genet. 2012; 3:126.
Bryant CD, Kole LA, Guido MA, Cheng R, Palmer AA. PMID: 22798962; PMCID: PMC3393886.
View in:
PubMed Mentions:
9
-
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest. 2012 Jun; 122(6):2306-15.
Distler MG, Plant LD, Sokoloff G, Hawk AJ, Aneas I, Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AA. PMID: 22585572; PMCID: PMC3366407.
View in:
PubMed Mentions:
68 Fields:
Translation:
Animals
-
Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis. Genes Brain Behav. 2012 Jul; 11(5):623-32.
Bryant CD, Kole LA, Guido MA, Sokoloff G, Palmer AA. PMID: 22487465; PMCID: PMC3691852.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
QTLs for murine red blood cell parameters in LG/J and SM/J F(2) and advanced intercross lines. Mamm Genome. 2012 Jun; 23(5-6):356-66.
Bartnikas TB, Parker CC, Cheng R, Campagna DR, Lim JE, Palmer AA, Fleming MD. PMID: 22322356; PMCID: PMC3358495.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics. 2012 Feb; 190(2):437-47.
Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. PMID: 22345611; PMCID: PMC3276626.
View in:
PubMed Mentions:
304 Fields:
Translation:
Animals
-
Genome-wide association for fear conditioning in an advanced intercross mouse line. Behav Genet. 2012 May; 42(3):437-48.
Parker CC, Sokoloff G, Cheng R, Palmer AA. PMID: 22237917; PMCID: PMC3351497.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
-
QTL Analysis of Type I and Type IIA Fibers in Soleus Muscle in a Cross between LG/J and SM/J Mouse Strains. Front Genet. 2011; 2:99.
Carroll AM, Palmer AA, Lionikas A. PMID: 22303393; PMCID: PMC3262224.
View in:
PubMed Mentions:
15
-
Genetic factors modulating the response to stimulant drugs in humans. Curr Top Behav Neurosci. 2012; 12:537-77.
Hart AB, de Wit H, Palmer AA. PMID: 22261702; PMCID: PMC3388157.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Translational genetic approaches to substance use disorders: bridging the gap between mice and humans. Hum Genet. 2012 Jun; 131(6):931-9.
Palmer AA, de Wit H. PMID: 22170288; PMCID: PMC3352994.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Genome-wide association for methamphetamine sensitivity in an advanced intercross mouse line. Genes Brain Behav. 2012 Feb; 11(1):52-61.
Parker CC, Cheng R, Sokoloff G, Palmer AA. PMID: 22032291; PMCID: PMC3368015.
View in:
PubMed Mentions:
24 Fields:
Translation:
Animals
-
Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids. Neuropsychopharmacology. 2012 Mar; 37(4):1026-35.
Bryant CD, Parker CC, Zhou L, Olker C, Chandrasekaran RY, Wager TT, Bolivar VJ, Loudon AS, Vitaterna MH, Turek FW, Palmer AA. PMID: 22089318; PMCID: PMC3280656.
View in:
PubMed Mentions:
33 Fields:
Translation:
Animals
-
Modulation ofTcf7l2 expression alters behavior in mice. PLoS One. 2011; 6(10):e26897.
Savic D, Distler MG, Sokoloff G, Shanahan NA, Dulawa SC, Palmer AA, Nobrega MA. PMID: 22046400; PMCID: PMC3203170.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Mapping a mouse limbic seizure susceptibility locus on chromosome 10. Epilepsia. 2011 Nov; 52(11):2076-83.
Winawer MR, Gildersleeve SS, Phillips AG, Rabinowitz D, Palmer AA. PMID: 21906048; PMCID: PMC3346290.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
QTLRel: an R package for genome-wide association studies in which relatedness is a concern. BMC Genet. 2011 Jul 27; 12:66.
Cheng R, Abney M, Palmer AA, Skol AD. PMID: 21794153; PMCID: PMC3160955.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
Pavlovian fear memory circuits and phenotype models of PTSD. Neuropharmacology. 2012 Feb; 62(2):638-46.
Johnson LR, McGuire J, Lazarus R, Palmer AA. PMID: 21782833.
View in:
PubMed Mentions:
54 Fields:
Translation:
Animals
-
Fine-mapping alleles for body weight in LG/J × SM/J F₂ and F(34) advanced intercross lines. Mamm Genome. 2011 Oct; 22(9-10):563-71.
Parker CC, Cheng R, Sokoloff G, Lim JE, Skol AD, Abney M, Palmer AA. PMID: 21761260; PMCID: PMC3308133.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug; 21(8):1223-38.
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, Manly KF, Miller DR, Donohue KD, Culiat CT, Churchill GA, Lariviere WR, Palmer AA, O'Hara BF, Voy BH, Chesler EJ. PMID: 21734011; PMCID: PMC3149490.
View in:
PubMed Mentions:
103 Fields:
Translation:
Animals
-
Genetic determinants for intramuscular fat content and water-holding capacity in mice selected for high muscle mass. Mamm Genome. 2011 Oct; 22(9-10):530-43.
Kärst S, Cheng R, Schmitt AO, Yang H, de Villena FP, Palmer AA, Brockmann GA. PMID: 21732194; PMCID: PMC3318964.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Dark matter: are mice the solution to missing heritability? Front Genet. 2011; 2:32.
Parker CC, Palmer AA. PMID: 22303328; PMCID: PMC3268586.
View in:
PubMed Mentions:
30
-
Casein kinase 1 enables nucleus accumbens amphetamine-induced locomotion by regulating AMPA receptor phosphorylation. J Neurochem. 2011 Jul; 118(2):237-47.
Li D, Herrera S, Bubula N, Nikitina E, Palmer AA, Hanck DA, Loweth JA, Vezina P. PMID: 21564097; PMCID: PMC3129449.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits. Genes Brain Behav. 2011 Jul; 10(5):604-14.
Sokoloff G, Parker CC, Lim JE, Palmer AA. PMID: 21554534; PMCID: PMC3756832.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
-
OPRM1 gene variants modulate amphetamine-induced euphoria in humans. Genes Brain Behav. 2011 Mar; 10(2):199-209.
Dlugos AM, Hamidovic A, Hodgkinson C, Shen PH, Goldman D, Palmer AA, de Wit H. PMID: 21029375; PMCID: PMC3377371.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Distinct genetic regions modify specific muscle groups in muscular dystrophy. Physiol Genomics. 2011 Jan 07; 43(1):24-31.
Swaggart KA, Heydemann A, Palmer AA, McNally EM. PMID: 20959497; PMCID: PMC3026347.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
Religion, spirituality, social support, and perceived stress in pregnant and postpartum Hispanic women. J Obstet Gynecol Neonatal Nurs. 2010 Nov-Dec; 39(6):645-57.
Mann JR, Mannan J, Quiñones LA, Palmer AA, Torres M. PMID: 21039849.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Murine Warriors or Worriers: The Saga of Comt1, B2 SINE Elements, and the Future of Translational Genetics. Front Neurosci. 2010; 4:177.
Palmer AA, Dulawa SC. PMID: 20976038; PMCID: PMC2958038.
View in:
PubMed Mentions:
5
-
More on ADORA. Psychopharmacology (Berl). 2010 Dec; 212(4):699-700.
Yang A, Childs E, Palmer AA, de Wit H. PMID: 20802997; PMCID: PMC4243305.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Fine mapping of QTL for prepulse inhibition in LG/J and SM/J mice using F(2) and advanced intercross lines. Genes Brain Behav. 2010 Oct; 9(7):759-67.
Samocha KE, Lim JE, Cheng R, Sokoloff G, Palmer AA. PMID: 20597988; PMCID: PMC3749925.
View in:
PubMed Mentions:
24 Fields:
Translation:
Animals
-
Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses. Physiol Genomics. 2010 Sep; 42A(1):33-8.
Lionikas A, Cheng R, Lim JE, Palmer AA, Blizard DA. PMID: 20627939; PMCID: PMC2957770.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Genetics of caffeine consumption and responses to caffeine. Psychopharmacology (Berl). 2010 Aug; 211(3):245-57.
Yang A, Palmer AA, de Wit H. PMID: 20532872; PMCID: PMC4242593.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansAnimals
-
Catechol-O-methyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatr Genet. 2010 Jun; 20(3):85-92.
Hamidovic A, Dlugos A, Palmer AA, de Wit H. PMID: 20414144; PMCID: PMC2875066.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCTClinical Trials
-
Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations. Genetics. 2010 Jul; 185(3):1033-44.
Cheng R, Lim JE, Samocha KE, Sokoloff G, Abney M, Skol AD, Palmer AA. PMID: 20439773; PMCID: PMC2907190.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
-
Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of D-amphetamine: an exploratory pharmacogenetic study using healthy volunteers. Behav Genet. 2010 Mar; 40(2):255-61.
Hamidovic A, Dlugos A, Palmer AA, de Wit H. PMID: 20091113; PMCID: PMC4454285.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Differences in aggressive behavior and DNA copy number variants between BALB/cJ and BALB/cByJ substrains. Behav Genet. 2010 Mar; 40(2):201-10.
Velez L, Sokoloff G, Miczek KA, Palmer AA, Dulawa SC. PMID: 20033273; PMCID: PMC3722062.
View in:
PubMed Mentions:
31 Fields:
Translation:
Animals
-
Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants. Exp Clin Psychopharmacol. 2009 Dec; 17(6):374-83.
Hamidovic A, Dlugos A, Skol A, Palmer AA, de Wit H. PMID: 19968402; PMCID: PMC2879583.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Are attention lapses related to d-amphetamine liking? Psychopharmacology (Berl). 2010 Feb; 208(2):201-9.
McCloskey M, Palmer AA, de Wit H. PMID: 19936714; PMCID: PMC4004179.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology. 2010 Feb; 35(3):613-22.
Dlugos AM, Hamidovic A, Hodgkinson CA, Goldman D, Palmer AA, de Wit H. PMID: 19890266; PMCID: PMC2945903.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest. 2009 Dec; 119(12):3703-12.
Heydemann A, Ceco E, Lim JE, Hadhazy M, Ryder P, Moran JL, Beier DR, Palmer AA, McNally EM. PMID: 19884661; PMCID: PMC2786802.
View in:
PubMed Mentions:
125 Fields:
Translation:
AnimalsCells
-
Further evidence of association between amphetamine response and SLC6A2 gene variants. Psychopharmacology (Berl). 2009 Oct; 206(3):501-11.
Dlugos AM, Hamidovic A, Palmer AA, de Wit H. PMID: 19727679; PMCID: PMC4242585.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. J Neural Transm (Vienna). 2009 Oct; 116(10):1323-34.
Dlugos AM, Palmer AA, de Wit H. PMID: 19657584; PMCID: PMC3653168.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice. Genes Brain Behav. 2009 Nov; 8(8):795-805.
Bryant CD, Chang HP, Zhang J, Wiltshire T, Tarantino LM, Palmer AA. PMID: 19694818; PMCID: PMC3697834.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. PLoS One. 2009; 4(3):e4649.
Williams R, Lim JE, Harr B, Wing C, Walters R, Distler MG, Teschke M, Wu C, Wiltshire T, Su AI, Sokoloff G, Tarantino LM, Borevitz JO, Palmer AA. PMID: 19266052; PMCID: PMC2650792.
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PubMed Mentions:
56 Fields:
Translation:
Animals
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Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies. PLoS One. 2009; 4(3):e4729.
Aldinger KA, Sokoloff G, Rosenberg DM, Palmer AA, Millen KJ. PMID: 19266100; PMCID: PMC2649211.
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PubMed Mentions:
70 Fields:
Translation:
Animals
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A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine. Psychopharmacology (Berl). 2009 May; 203(4):703-11.
Bryant CD, Graham ME, Distler MG, Munoz MB, Li D, Vezina P, Sokoloff G, Palmer AA. PMID: 19050854; PMCID: PMC2729782.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Prenatal protein deprivation alters dopamine-mediated behaviors and dopaminergic and glutamatergic receptor binding. Brain Res. 2008 Oct 27; 1237:62-74.
Palmer AA, Brown AS, Keegan D, Siska LD, Susser E, Rotrosen J, Butler PD. PMID: 18703024; PMCID: PMC2591022.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Rapid selection response for contextual fear conditioning in a cross between C57BL/6J and A/J: behavioral, QTL and gene expression analysis. Behav Genet. 2008 May; 38(3):277-91.
Ponder CA, Huded CP, Munoz MB, Gulden FO, Gilliam TC, Palmer AA. PMID: 18363093; PMCID: PMC5588860.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Behavioral differences among C57BL/6 substrains: implications for transgenic and knockout studies. J Neurogenet. 2008; 22(4):315-31.
Bryant CD, Zhang NN, Sokoloff G, Fanselow MS, Ennes HS, Palmer AA, McRoberts JA. PMID: 19085272; PMCID: PMC3697827.
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PubMed Mentions:
118 Fields:
Translation:
Animals
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Acute and chronic responses to the convulsant pilocarpine in DBA/2J and A/J mice. Neuroscience. 2007 Oct 26; 149(2):465-75.
Winawer MR, Makarenko N, McCloskey DP, Hintz TM, Nair N, Palmer AA, Scharfman HE. PMID: 17904758; PMCID: PMC2640947.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Significance thresholds for quantitative trait locus mapping under selective genotyping. Genetics. 2007 Nov; 177(3):1963-6.
Manichaikul A, Palmer AA, Sen S, Broman KW. PMID: 17720902; PMCID: PMC2147971.
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PubMed Mentions:
16 Fields:
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Genetic architecture of fear conditioning in chromosome substitution strains: relationship to measures of innate (unlearned) anxiety-like behavior. Mamm Genome. 2007 Apr; 18(4):221-8.
Ponder CA, Munoz M, Gilliam TC, Palmer AA. PMID: 17492333.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Selection for contextual fear conditioning affects anxiety-like behaviors and gene expression. Genes Brain Behav. 2007 Nov; 6(8):736-49.
Ponder CA, Kliethermes CL, Drew MR, Muller J, Das K, Risbrough VB, Crabbe JC, Gilliam TC, Palmer AA. PMID: 17309658.
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PubMed Mentions:
49 Fields:
Translation:
Animals
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Use of chromosome substitution strains to identify seizure susceptibility loci in mice. Mamm Genome. 2007 Jan; 18(1):23-31.
Winawer MR, Kuperman R, Niethammer M, Sherman S, Rabinowitz D, Guell IP, Ponder CA, Palmer AA. PMID: 17242861; PMCID: PMC2640942.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Sensitivity to the locomotor-stimulant effects of ethanol and allopregnanolone: a quantitative trait locus study of common genetic influence. Genes Brain Behav. 2006 Oct; 5(7):506-17.
Palmer AA, Lessov-Schlaggar CN, Ponder CA, McKinnon CS, Phillips TJ. PMID: 17010097.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Association between the casein kinase 1 epsilon gene region and subjective response to D-amphetamine. Neuropsychopharmacology. 2006 May; 31(5):1056-63.
Veenstra-VanderWeele J, Qaadir A, Palmer AA, Cook EH, de Wit H. PMID: 16237383.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Hardy-Weinberg disequilibrium identified genotyping error of the serotonin transporter (SLC6A4) promoter polymorphism. Psychiatr Genet. 2006 Feb; 16(1):31-4.
Yonan AL, Palmer AA, Gilliam TC. PMID: 16395127.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome. 2005 May; 16(5):291-305.
Palmer AA, Verbitsky M, Suresh R, Kamens HM, Reed CL, Li N, Burkhart-Kasch S, McKinnon CS, Belknap JK, Gilliam TC, Phillips TJ. PMID: 16104378.
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PubMed Mentions:
57 Fields:
Translation:
Animals
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Behavioral sensitization to ethanol is modulated by environmental conditions, but is not associated with cross-sensitization to allopregnanolone or pentobarbital in DBA/2J mice. Neuroscience. 2005; 131(2):263-73.
Meyer PJ, Palmer AA, McKinnon CS, Phillips TJ. PMID: 15708471.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet. 2004 Nov; 36(11):1133-7.
Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium. PMID: 15514660.
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PubMed Mentions:
603 Fields:
Translation:
HumansAnimals
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Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol. Psychopharmacology (Berl). 2004 Nov; 176(3-4):386-97.
Palmer AA, Sharpe AL, Burkhart-Kasch S, McKinnon CS, Coste SC, Stenzel-Poore MP, Phillips TJ. PMID: 15138758.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding. Brain Res. 2004 Jan 23; 996(2):193-201.
Palmer AA, Printz DJ, Butler PD, Dulawa SC, Printz MP. PMID: 14697497.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet. 2003 Nov; 4(11):911-6.
Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, Churchill GA, Cook M, Crabbe JC, Crusio WE, Darvasi A, de Haan G, Dermant P, Doerge RW, Elliot RW, Farber CR, Flaherty L, Flint J, Gershenfeld H, Gibson JP, Gu J, Gu W, Himmelbauer H, Hitzemann R, Hsu HC, Hunter K, Iraqi FF, Jansen RC, Johnson TE, Jones BC, Kempermann G, Lammert F, Lu L, Manly KF, Matthews DB, Medrano JF, Mehrabian M, Mittlemann G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Mountz JD, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Paigen B, Palmer AA, Peirce JL, Pomp D, Rosemann M, Rosen GD, Schalkwyk LC, Seltzer Z, Settle S, Shimomura K, Shou S, Sikela JM, Siracusa LD, Spearow JL, Teuscher C, Threadgill DW, Toth LA, Toye AA, Vadasz C, Van Zant G, Wakeland E, Williams RW, Zhang HG, Zou F, Complex Trait Consortium. PMID: 14634638; PMCID: PMC2063446.
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PubMed Mentions:
183 Fields:
Translation:
HumansAnimals
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Bioinformatic analysis of autism positional candidate genes using biological databases and computational gene network prediction. Genes Brain Behav. 2003 Oct; 2(5):303-20.
Yonan AL, Palmer AA, Smith KC, Feldman I, Lee HK, Yonan JM, Fischer SG, Pavlidis P, Gilliam TC. PMID: 14606695.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Reverse selection for differential response to the locomotor stimulant effects of ethanol provides evidence for pleiotropic genetic influence on locomotor response to other drugs of abuse. Alcohol Clin Exp Res. 2003 Oct; 27(10):1535-47.
Bergstrom HC, Palmer AA, Wood RD, Burkhart-Kasch S, McKinnon CS, Phillips TJ. PMID: 14574223.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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A genomewide screen of 345 families for autism-susceptibility loci. Am J Hum Genet. 2003 Oct; 73(4):886-97.
Yonan AL, Alarcón M, Cheng R, Magnusson PK, Spence SJ, Palmer AA, Grunn A, Juo SH, Terwilliger JD, Liu J, Cantor RM, Geschwind DH, Gilliam TC. PMID: 13680528; PMCID: PMC1180610.
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PubMed Mentions:
92 Fields:
Translation:
Humans
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Effects of a Drd2 deletion mutation on ethanol-induced locomotor stimulation and sensitization suggest a role for epistasis. Behav Genet. 2003 May; 33(3):311-24.
Palmer AA, Low MJ, Grandy DK, Phillips TJ. PMID: 12837020.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Inappropriate choice of the experimental unit leads to a dramatic overestimation of the significance of quantitative trait loci for prepulse inhibition and startle response in recombinant congenic mice. Neuropsychopharmacology. 2003 Apr; 28(4):818; author reply 819.
Palmer AA, Airey DC. PMID: 12655329.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Locomotor activity responses to ethanol, other alcohols, and GABA-A acting compounds in forward- and reverse-selected FAST and SLOW mouse lines. Behav Neurosci. 2002 Dec; 116(6):958-67.
Palmer AA, McKinnon CS, Bergstrom HC, Phillips TJ. PMID: 12492294.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Identification of quantitative trait loci for prepulse inhibition in rats. Psychopharmacology (Berl). 2003 Jan; 165(3):270-9.
Palmer AA, Breen LL, Flodman P, Conti LH, Spence MA, Printz MP. PMID: 12426667.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Effect of forward and reverse selection for ethanol-induced locomotor response on other measures of ethanol sensitivity. Alcohol Clin Exp Res. 2002 Sep; 26(9):1322-9.
Palmer AA, Phillips TJ. PMID: 12351925.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Initial sensitivity, tolerance and cross-tolerance to allopregnanolone- and ethanol-induced hypothermia in selected mouse lines. Psychopharmacology (Berl). 2002 Jul; 162(3):313-22.
Palmer AA, Moyer MR, Crabbe JC, Phillips TJ. PMID: 12122490.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Forward, relaxed, and reverse selection for reduced and enhanced sensitivity to ethanol's locomotor stimulant effects in mice. Alcohol Clin Exp Res. 2002 May; 26(5):593-602.
Phillips TJ, Shen EH, McKinnon CS, Burkhart-Kasch S, Lessov CN, Palmer AA. PMID: 12045466.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Photochemical control of the infectivity of adenoviral vectors using a novel photocleavable biotinylation reagent. Chem Biol. 2002 May; 9(5):567-73.
Pandori MW, Hobson DA, Olejnik J, Krzymanska-Olejnik E, Rothschild KJ, Palmer AA, Phillips TJ, Sano T. PMID: 12031663.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Differences between SHR and WKY following the airpuff startle stimulus in the number of Fos expressing, RVLM projecting neurons. Clin Exp Hypertens. 2002 Apr; 24(3):125-39.
Palmer AA, Printz MP. PMID: 11883788.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes. Behav Neurosci. 2002 Feb; 116(1):126-37.
Palmer AA, Miller MN, McKinnon CS, Phillips TJ. PMID: 11895174.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Latent inhibition and conditioning in rat strains which show differential prepulse inhibition. Behav Genet. 2001 May; 31(3):325-33.
Conti LH, Palmer AA, Vanella JJ, Printz MP. PMID: 11699605.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Voluntary ethanol drinking in C57BL/6J and DBA/2J mice before and after sensitization to the locomotor stimulant effects of ethanol. Psychopharmacology (Berl). 2001 Apr; 155(1):91-9.
Lessov CN, Palmer AA, Quick EA, Phillips TJ. PMID: 11374341.
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PubMed Mentions:
42 Fields:
Translation:
Animals
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Prepulse startle deficit in the Brown Norway rat: a potential genetic model. Behav Neurosci. 2000 Apr; 114(2):374-88.
Palmer AA, Dulawa SC, Mottiwala AA, Conti LH, Geyer MA, Printz MP. PMID: 10832798.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Airpuff startle stress elicited fos expression in brain cardiovascular areas of young SHR and WKY rats. Clin Exp Hypertens. 1999 Oct; 21(7):1061-81.
Palmer AA, Printz MP. PMID: 10513828.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Strain differences in Fos expression following airpuff startle in Spontaneously Hypertensive and Wistar Kyoto rats. Neuroscience. 1999 Mar; 89(3):965-78.
Palmer AA, Printz MP. PMID: 10199628.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Angiotensin II receptor binding sites in the ventral portion of the bed nucleus of the stria terminalis are reduced by interruption of the medial forebrain bundle. Brain Res. 1998 Oct 26; 809(1):5-11.
Grove KL, Speth RC, Palmer AA, Ganong WF, Steele MK. PMID: 9795102.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Attenuation of Fos expression to airpuff startle stimuli following tympanic membrane rupture. Brain Res. 1998 Mar 16; 787(1):91-8.
Palmer AA, Printz MP. PMID: 9518564.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Evidence for differences in cultured left ventricular fibroblast populations isolated from spontaneously hypertensive and Wistar-Kyoto rats. J Hypertens. 1995 Dec; 13(12 Pt 1):1421-31.
Klett CP, Palmer AA, Dirig DM, Gallagher AM, Riosecco-Camacho N, Printz MP. PMID: 8866904.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Differences in cultured cardiac fibroblast populations isolated from SHR and WKY rats. Clin Exp Pharmacol Physiol Suppl. 1995 Dec; 22(1):S265-7.
Klett CP, Palmer A, Gallagher AM, Rioseco-Camacho N, Printz MP. PMID: 9072384.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Intravenous losartan inhibits the increase in plasma luteinizing hormone and water intake produced by intraventricular angiotensin II. Proc Soc Exp Biol Med. 1994 Mar; 205(3):263-6.
Palmer AA, Steele MK, Shackelford RL, Ganong WF. PMID: 8171048.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Involvement of central corticotropin-releasing factor (CRF) in suckling-induced inhibition of luteinizing hormone secretion in lactating rats. J Neuroendocrinol. 1993 Aug; 5(4):451-9.
Walker CD, Dallman MF, Palmer AA, Steele MK. PMID: 8401569.
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PubMed Mentions:
1 Fields:
Translation:
Animals