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CXCL12 drives natural variation in coronary artery anatomy across diverse populations. medRxiv. 2024 Jul 05.
Rios Coronado PE, Zanetti D, Zhou J, Naftaly JA, Prabala P, Martínez Jaimes AM, Farah EN, Fan X, Kundu S, Deshpande SS, Evergreen I, Kho PF, Hilliard AT, Abramowitz S, Pyarajan S, Dochtermann D, Million Veteran Program, Damrauer SM, Chang KM, Levin MG, Winn VD, Pasca AM, Plomondon ME, Waldo SW, Tsao PS, Kundaje A, Chi NC, Clarke SL, Red-Horse K, Assimes TL. PMID: 37961706; PMCID: PMC10635223.
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Spatially organized cellular communities form the developing human heart. Nature. 2024 Mar; 627(8005):854-864.
Farah EN, Hu RK, Kern C, Zhang Q, Lu TY, Ma Q, Tran S, Zhang B, Carlin D, Monell A, Blair AP, Wang Z, Eschbach J, Li B, Destici E, Ren B, Evans SM, Chen S, Zhu Q, Chi NC. PMID: 38480880; PMCID: PMC10972757.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Coordinating the first heartbeat. Nature. 2023 Oct; 622(7981):37-39.
Bloomekatz J, Chi NC. PMID: 37759109.
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Nuclear mechanosignaling in striated muscle diseases. Front Physiol. 2023; 14:1126111.
Zhang B, Powers JD, McCulloch AD, Chi NC. PMID: 36960155; PMCID: PMC10027932.
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Fishing Out the Role of RBPMS2 in Cardiac Splicing. Circ Res. 2022 12 02; 131(12):1001-1003.
Holman AR, Chi NC. PMID: 36454855.
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PubMed Mentions: Fields:
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Cells
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Author Correction: Human-gained heart enhancers are associated with species-specific cardiac attributes. Nat Cardiovasc Res. 2022 Dec; 1(12):1231.
Destici E, Zhu F, Tran S, Preissl S, Farah EN, Zhang Y, Hou X, Poirion OB, Lee AY, Grinstein JD, Bloomekatz J, Kim HS, Hu R, Evans SM, Ren B, Benner C, Chi NC. PMID: 39196171.
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Human-gained heart enhancers are associated with species-specific cardiac attributes. Nat Cardiovasc Res. 2022 Sep; 1(9):830-843.
Destici E, Zhu F, Tran S, Preissl S, Farah EN, Zhang Y, Hou X, Poirion OB, Lee AY, Grinstein JD, Bloomekatz J, Kim HS, Hu R, Evans SM, Ren B, Benner C, Chi NC. PMID: 36817700; PMCID: PMC9937543.
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2
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Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis. Bioinform Adv. 2022; 2(1):vbac051.
Blair AP, Hu RK, Farah EN, Chi NC, Pollard KS, Przytycki PF, Kathiriya IS, Bruneau BG. PMID: 35967929; PMCID: PMC9362878.
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Ankfn1-mutant vestibular defects require loss of both ancestral and derived paralogs for penetrance in zebrafish. G3 (Bethesda). 2022 03 04; 12(3).
Ross KD, Ren J, Zhang R, Chi NC, Hamilton BA. PMID: 35100349; PMCID: PMC9210315.
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PubMed Mentions: Fields:
Translation:
Animals
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Screening, identification, purification and homologous modeling of marine cold-active alpha-amylase. Cryo Letters. 2021 Nov-Dec; 42(6):341-352.
Lu M, Li C, Liu C, Chi N, Dou S. PMID: 35366300.
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Translation:
Cells
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A convergent molecular network underlying autism and congenital heart disease. Cell Syst. 2021 11 17; 12(11):1094-1107.e6.
Rosenthal SB, Willsey HR, Xu Y, Mei Y, Dea J, Wang S, Curtis C, Sempou E, Khokha MK, Chi NC, Willsey AJ, Fisch KM, Ideker T. PMID: 34411509; PMCID: PMC8602730.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Unveiling Complexity and Multipotentiality of Early Heart Fields. Circ Res. 2021 08 06; 129(4):474-487.
Zhang Q, Carlin D, Zhu F, Cattaneo P, Ideker T, Evans SM, Bloomekatz J, Chi NC. PMID: 34162224; PMCID: PMC9308985.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Cardiac cell type-specific gene regulatory programs and disease risk association. Sci Adv. 2021 05; 7(20).
Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang TM, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B, Chi NC, Preissl S. PMID: 33990324; PMCID: PMC8121433.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Cardiac Morphogenesis: Crowding and Tension Resolved through Social Distancing. Dev Cell. 2021 01 25; 56(2):159-160.
Bloomekatz J, Diaz JT, Yelon D, Chi NC. PMID: 33497621; PMCID: PMC8552508.
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Translation:
CellsPHPublic Health
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Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract. Development. 2020 06 17; 147(12).
Sidhwani P, Leerberg DM, Boezio GLM, Capasso TL, Yang H, Chi NC, Roman BL, Stainier DYR, Yelon D. PMID: 32439760; PMCID: PMC7328156.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure. Nat Commun. 2020 02 28; 11(1):1122.
Arvanitis M, Tampakakis E, Zhang Y, Wang W, Auton A, 23andMe Research Team, Dutta D, Glavaris S, Keramati A, Chatterjee N, Chi NC, Ren B, Post WS, Battle A. PMID: 32111823; PMCID: PMC7048760.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells. Nat Genet. 2019 09; 51(9):1380-1388.
Zhang Y, Li T, Preissl S, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B. PMID: 31427791; PMCID: PMC6722002.
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PubMed Mentions:
137 Fields:
Translation:
HumansAnimalsCells
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Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes. Dev Cell. 2019 09 23; 50(6):729-743.e5.
Ren J, Han P, Ma X, Farah EN, Bloomekatz J, Zeng XI, Zhang R, Swim MM, Witty AD, Knight HG, Deshpande R, Xu W, Yelon D, Chen S, Chi NC. PMID: 31402282; PMCID: PMC6759400.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming. Elife. 2019 06 25; 8.
Gálvez-Santisteban M, Chen D, Zhang R, Serrano R, Nguyen C, Zhao L, Nerb L, Masutani EM, Vermot J, Burns CG, Burns CE, Del Álamo JC, Chi NC. PMID: 31237233; PMCID: PMC6592682.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Combinatorial interactions of genetic variants in human cardiomyopathy. Nat Biomed Eng. 2019 02; 3(2):147-157.
Deacon DC, Happe CL, Chen C, Tedeschi N, Manso AM, Li T, Dalton ND, Peng Q, Farah EN, Gu Y, Tenerelli KP, Tran VD, Chen J, Peterson KL, Schork NJ, Adler ED, Engler AJ, Ross RS, Chi NC. PMID: 30923642; PMCID: PMC6433174.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports. 2018 09 11; 11(3):828-841.
Veevers J, Farah EN, Corselli M, Witty AD, Palomares K, Vidal JG, Emre N, Carson CT, Ouyang K, Liu C, van Vliet P, Zhu M, Hegarty JM, Deacon DC, Grinstein JD, Dirschinger RJ, Frazer KA, Adler ED, Knowlton KU, Chi NC, Martin JC, Chen J, Evans SM. PMID: 30122443; PMCID: PMC6135222.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Corrigendum: Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature. 2018 03 21; 555(7697):543.
Reischauer S, Stone OA, Villasenor A, Chi N, Jin SW, Martin M, Lee MT, Fukuda N, Marass M, Witty A, Fiddes I, Kuo T, Chung WS, Salek S, Lerrigo R, Alsiö J, Luo S, Tworus D, Augustine SM, Mucenieks S, Nystedt B, Giraldez AJ, Schroth GP, Andersson O, Stainier DYR. PMID: 29565360.
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PubMed Mentions: Fields:
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Re-evaluating the functional landscape of the cardiovascular system during development. Biol Open. 2017 Nov 15; 6(11):1756-1770.
Takada N, Omae M, Sagawa F, Chi NC, Endo S, Kozawa S, Sato TN. PMID: 28982700; PMCID: PMC5703621.
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PubMed Mentions:
5 Fields:
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Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway. Blood. 2017 08 03; 130(5):666-676.
Hu Z, Liu Y, Huarng MC, Menegatti M, Reyon D, Rost MS, Norris ZG, Richter CE, Stapleton AN, Chi NC, Peyvandi F, Joung JK, Shavit JA. PMID: 28576875; PMCID: PMC5542852.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Impaired mitophagy facilitates mitochondrial damage in Danon disease. J Mol Cell Cardiol. 2017 07; 108:86-94.
Hashem SI, Murphy AN, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. PMID: 28526246.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Stem Cell Reports. 2017 04 11; 8(4):1086-1100.
Panopoulos AD, D'Antonio M, Benaglio P, Williams R, Hashem SI, Schuldt BM, DeBoever C, Arias AD, Garcia M, Nelson BC, Harismendy O, Jakubosky DA, Donovan MKR, Greenwald WW, Farnam K, Cook M, Borja V, Miller CA, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Aguirre A, McGarry TJ, Matsui H, Li H, Reyna J, Rao F, O'Connor DT, Yeo GW, Evans SM, Chi NC, Jepsen K, Nariai N, Müller FJ, Goldstein LSB, Izpisua Belmonte JC, Adler E, Loring JF, Berggren WT, D'Antonio-Chronowska A, Smith EN, Frazer KA. PMID: 28410642; PMCID: PMC5390244.
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PubMed Mentions:
79 Fields:
Translation:
HumansCells
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FGF signaling enforces cardiac chamber identity in the developing ventricle. Development. 2017 04 01; 144(7):1328-1338.
Pradhan A, Zeng XI, Sidhwani P, Marques SR, George V, Targoff KL, Chi NC, Yelon D. PMID: 28232600; PMCID: PMC5399623.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017 Mar; 49(3):457-464.
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çaglayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG. PMID: 28092684; PMCID: PMC5325768.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Myocardial plasticity: cardiac development, regeneration and disease. Curr Opin Genet Dev. 2016 10; 40:120-130.
Bloomekatz J, Galvez-Santisteban M, Chi NC. PMID: 27498024; PMCID: PMC5988255.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. J Clin Invest. 2016 08 01; 126(8):3158.
Lee J, Fei P, Sevag Packard RR, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Kuo CC, Chi NC, Ho CM, Li R, Hsiai TK. PMID: 27479748; PMCID: PMC4966324.
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PubMed Mentions:
6 Fields:
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Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly. Am J Hum Genet. 2016 Aug 04; 99(2):501-10.
Li H, Bielas SL, Zaki MS, Ismail S, Farfara D, Um K, Rosti RO, Scott EC, Tu S, Chi NC, Gabriel S, Erson-Omay EZ, Ercan-Sencicek AG, Yasuno K, Çaglayan AO, Kaymakçalan H, Ekici B, Bilguvar K, Gunel M, Gleeson JG. PMID: 27453578; PMCID: PMC4974110.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature. 2016 07 14; 535(7611):294-8.
Reischauer S, Stone OA, Villasenor A, Chi N, Jin SW, Martin M, Lee MT, Fukuda N, Marass M, Witty A, Fiddes I, Kuo T, Chung WS, Salek S, Lerrigo R, Alsiö J, Luo S, Tworus D, Augustine SM, Mucenieks S, Nystedt B, Giraldez AJ, Schroth GP, Andersson O, Stainier DY. PMID: 27411634.
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PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
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Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016 06 30; 534(7609):700-4.
Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns CE, Anderson RM, Chi NC. PMID: 27357797; PMCID: PMC5330678.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. J Clin Invest. 2016 05 02; 126(5):1679-90.
Lee J, Fei P, Packard RR, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Kuo CC, Chi NC, Ho CM, Li R, Hsiai TK. PMID: 27018592; PMCID: PMC4855946.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Effect of p53 gene polymorphism on functions of prostate cancer cells. Genet Mol Res. 2015 Oct 02; 14(4):11700-9.
Chi N, Yun ZZ, Tan ZH, Li XZ, Chen BT, Liu J, Xu LB, Ma KW, Li SX, Liu JF, Liu CX. PMID: 26436494.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Myocardium and BMP signaling are required for endocardial differentiation. Development. 2015 Jul 01; 142(13):2304-15.
Palencia-Desai S, Rost MS, Schumacher JA, Ton QV, Craig MP, Baltrunaite K, Koenig AL, Wang J, Poss KD, Chi NC, Stainier DY, Sumanas S. PMID: 26092845; PMCID: PMC4510589.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 Jul; 47(7):809-13.
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. PMID: 26005868; PMCID: PMC4547531.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Dev Biol. 2015 Aug 15; 404(2):49-60.
Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC. PMID: 26004360; PMCID: PMC4515213.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. Stem Cells. 2015 Jul; 33(7):2343-50.
Hashem SI, Perry CN, Bauer M, Han S, Clegg SD, Ouyang K, Deacon DC, Spinharney M, Panopoulos AD, Izpisua Belmonte JC, Frazer KA, Chen J, Gong Q, Zhou Z, Chi NC, Adler ED. PMID: 25826782; PMCID: PMC4651661.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Isolation and characterization of cancer stem cells from medulloblastoma. Genet Mol Res. 2015 Apr 13; 14(2):3355-61.
Liu J, Chi N, Zhang JY, Zhu W, Bian YS, Chen HG. PMID: 25966102.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Notch signaling regulates venous arterialization during zebrafish fin regeneration. Genes Cells. 2015 May; 20(5):427-38.
Kametani Y, Chi NC, Stainier DY, Takada S. PMID: 25810153; PMCID: PMC4996968.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Integrative analysis of haplotype-resolved epigenomes across human tissues. Nature. 2015 Feb 19; 518(7539):350-354.
Leung D, Jung I, Rajagopal N, Schmitt A, Selvaraj S, Lee AY, Yen CA, Lin S, Lin Y, Qiu Y, Xie W, Yue F, Hariharan M, Ray P, Kuan S, Edsall L, Yang H, Chi NC, Zhang MQ, Ecker JR, Ren B. PMID: 25693566; PMCID: PMC4449149.
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PubMed Mentions:
121 Fields:
Translation:
HumansCells
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Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors. Neuron. 2015 Jan 07; 85(1):228.
Mishra-Gorur K, Çaglayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüs GT, Nishimura S, Han W, Tu S, Baran B, Gümüs H, Dilber C, Zaki MS, Hossni HAA, Rivière JB, Kayserili H, Spencer EG, Rosti RÖ, Schroth J, Per H, Çaglar C, Çaglar Ç, Dölen D, Baranoski JF, Kumandas S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Šestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M. PMID: 29654772.
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PubMed Mentions:
4 Fields:
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Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors. Neuron. 2014 Dec 17; 84(6):1226-39.
Mishra-Gorur K, Çaglayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüs GT, Nishimura S, Han W, Tu S, Baran B, Gümüs H, Dilber C, Zaki MS, Hossni HA, Rivière JB, Kayserili H, Spencer EG, Rosti RÖ, Schroth J, Per H, Çaglar C, Çaglar Ç, Dölen D, Baranoski JF, Kumandas S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Šestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M. PMID: 25521378; PMCID: PMC5024344.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos. Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2268-75.
Li R, Beebe T, Jen N, Yu F, Takabe W, Harrison M, Cao H, Lee J, Yang H, Han P, Wang K, Shimizu H, Chen J, Lien CL, Chi NC, Hsiai TK. PMID: 25147335; PMCID: PMC4169303.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Wearable multi-channel microelectrode membranes for elucidating electrophysiological phenotypes of injured myocardium. Integr Biol (Camb). 2014 Aug; 6(8):789-95.
Cao H, Yu F, Zhao Y, Zhang X, Tai J, Lee J, Darehzereshki A, Bersohn M, Lien CL, Chi NC, Tai YC, Hsiai TK. PMID: 24945366; PMCID: PMC4124744.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 2014 May 15; 389(2):182-91.
Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC. PMID: 24607366; PMCID: PMC4101123.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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3-OST-7 regulates BMP-dependent cardiac contraction. PLoS Biol. 2013 Dec; 11(12):e1001727.
Samson SC, Ferrer T, Jou CJ, Sachse FB, Shankaran SS, Shaw RM, Chi NC, Tristani-Firouzi M, Yost HJ. PMID: 24311987; PMCID: PMC3849020.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]. J Am Coll Cardiol. 2014 Feb 04; 63(4):358-68.
Zhang K, Deacon DC, Rao F, Schork AJ, Fung MM, Waalen J, Schork NJ, Nievergelt CM, Chi NC, O'Connor DT. PMID: 24140660; PMCID: PMC3946708.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Moving domain computational fluid dynamics to interface with an embryonic model of cardiac morphogenesis. PLoS One. 2013; 8(8):e72924.
Lee J, Moghadam ME, Kung E, Cao H, Beebe T, Miller Y, Roman BL, Lien CL, Chi NC, Marsden AL, Hsiai TK. PMID: 24009714; PMCID: PMC3751826.
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PubMed Mentions:
37 Fields:
Translation:
Animals
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Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell. 2013 Aug 01; 13(2):246-54.
Yoshioka N, Gros E, Li HR, Kumar S, Deacon DC, Maron C, Muotri AR, Chi NC, Fu XD, Yu BD, Dowdy SF. PMID: 23910086; PMCID: PMC3845961.
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PubMed Mentions:
141 Fields:
Translation:
HumansAnimalsCells
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An evolutionarily conserved program of B-cell development and activation in zebrafish. Blood. 2013 Aug 22; 122(8):e1-11.
Page DM, Wittamer V, Bertrand JY, Lewis KL, Pratt DN, Delgado N, Schale SE, McGue C, Jacobsen BH, Doty A, Pao Y, Yang H, Chi NC, Magor BG, Traver D. PMID: 23861249; PMCID: PMC3750348.
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PubMed Mentions:
90 Fields:
Translation:
AnimalsCells
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In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 2013 Jun 27; 498(7455):497-501.
Zhang R, Han P, Yang H, Ouyang K, Lee D, Lin YF, Ocorr K, Kang G, Chen J, Stainier DY, Yelon D, Chi NC. PMID: 23783515; PMCID: PMC4090927.
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PubMed Mentions:
120 Fields:
Translation:
AnimalsCells
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Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell. 2013 May 23; 153(5):1134-48.
Xie W, Schultz MD, Lister R, Hou Z, Rajagopal N, Ray P, Whitaker JW, Tian S, Hawkins RD, Leung D, Yang H, Wang T, Lee AY, Swanson SA, Zhang J, Zhu Y, Kim A, Nery JR, Urich MA, Kuan S, Yen CA, Klugman S, Yu P, Suknuntha K, Propson NE, Chen H, Edsall LE, Wagner U, Li Y, Ye Z, Kulkarni A, Xuan Z, Chung WY, Chi NC, Antosiewicz-Bourget JE, Slukvin I, Stewart R, Zhang MQ, Wang W, Thomson JA, Ecker JR, Ren B. PMID: 23664764; PMCID: PMC3786220.
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PubMed Mentions:
426 Fields:
Translation:
HumansAnimalsCells
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UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development. Development. 2013 Apr; 140(8):1713-9.
Hegarty JM, Yang H, Chi NC. PMID: 23533172; PMCID: PMC3621489.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Zebrafish cardiac injury and regeneration models: a noninvasive and invasive in vivo model of cardiac regeneration. Methods Mol Biol. 2013; 1037:463-73.
Dickover MS, Zhang R, Han P, Chi NC. PMID: 24029953; PMCID: PMC4159160.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Zebrafish models in cardiac development and congenital heart birth defects. Differentiation. 2012 Jul; 84(1):4-16.
Tu S, Chi NC. PMID: 22704690; PMCID: PMC4099249.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimals
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Flexible microelectrode arrays to interface epicardial electrical signals with intracardial calcium transients in zebrafish hearts. Biomed Microdevices. 2012 Apr; 14(2):357-66.
Yu F, Zhao Y, Gu J, Quigley KL, Chi NC, Tai YC, Hsiai TK. PMID: 22124886; PMCID: PMC3322508.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease. Dev Biol. 2012 Feb 15; 362(2):121-31.
Yoruk B, Gillers BS, Chi NC, Scott IC. PMID: 22182521.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May; 9(5):812-20.
Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. PMID: 22138472; PMCID: PMC3306544.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development. 2011 Nov; 138(21):4721-32.
Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S. PMID: 21989916; PMCID: PMC3190385.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13576-81.
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. PMID: 21825130; PMCID: PMC3158173.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Mol Cell Biol. 2011 Apr; 31(7):1344-56.
Amigo JD, Yu M, Troadec MB, Gwynn B, Cooney JD, Lambert AJ, Chi NC, Weiss MJ, Peters LL, Kaplan J, Cantor AB, Paw BH. PMID: 21248200; PMCID: PMC3135305.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Evolving cardiac conduction phenotypes in developing zebrafish larvae: implications to drug sensitivity. Zebrafish. 2010 Dec; 7(4):325-31.
Yu F, Huang J, Adlerz K, Jadvar H, Hamdan MH, Chi N, Chen JN, Hsiai TK. PMID: 20958244; PMCID: PMC3005146.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Cardiac conduction is required to preserve cardiac chamber morphology. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14662-7.
Chi NC, Bussen M, Brand-Arzamendi K, Ding C, Olgin JE, Shaw RM, Martin GR, Stainier DY. PMID: 20675583; PMCID: PMC2930423.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010 Mar 04; 464(7285):108-11.
Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. PMID: 20154733; PMCID: PMC2858358.
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PubMed Mentions:
531 Fields:
Translation:
AnimalsCells
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Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan; 120(1):266-79.
Smyth JW, Hong TT, Gao D, Vogan JM, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM. PMID: 20038810; PMCID: PMC2798685.
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PubMed Mentions:
140 Fields:
Translation:
HumansAnimalsCells
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Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol. 2009 Oct 01; 334(1):213-23.
Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halpern M, Stainier DY. PMID: 19631206; PMCID: PMC2759669.
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PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
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Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat Genet. 2009 Apr; 41(4):396-8.
Hogan BM, Bos FL, Bussmann J, Witte M, Chi NC, Duckers HJ, Schulte-Merker S. PMID: 19287381.
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PubMed Mentions:
200 Fields:
Translation:
HumansAnimalsCells
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Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell. 2008 Dec 12; 135(6):1053-64.
De Val S, Chi NC, Meadows SM, Minovitsky S, Anderson JP, Harris IS, Ehlers ML, Agarwal P, Visel A, Xu SM, Pennacchio LA, Dubchak I, Krieg PA, Stainier DY, Black BL. PMID: 19070576; PMCID: PMC2782666.
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PubMed Mentions:
193 Fields:
Translation:
HumansAnimalsCells
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Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13; 6(5):e109.
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. PMID: 18479184; PMCID: PMC2430899.
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PubMed Mentions:
132 Fields:
Translation:
Animals
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Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev. 2008 Mar 15; 22(6):734-9.
Chi NC, Shaw RM, De Val S, Kang G, Jan LY, Black BL, Stainier DY. PMID: 18347092; PMCID: PMC2275426.
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PubMed Mentions:
207 Fields:
Translation:
AnimalsCells
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Zebrafish model for human long QT syndrome. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11316-21.
Arnaout R, Ferrer T, Huisken J, Spitzer K, Stainier DY, Tristani-Firouzi M, Chi NC. PMID: 17592134; PMCID: PMC2040896.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimals
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A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Dev Biol. 2007 Jul 01; 307(1):29-42.
Jin SW, Herzog W, Santoro MM, Mitchell TS, Frantsve J, Jungblut B, Beis D, Scott IC, D'Amico LA, Ober EA, Verkade H, Field HA, Chi NC, Wehman AM, Baier H, Stainier DY. PMID: 17531218; PMCID: PMC2695512.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Targeting neural circuitry in zebrafish using GAL4 enhancer trapping. Nat Methods. 2007 Apr; 4(4):323-6.
Scott EK, Mason L, Arrenberg AB, Ziv L, Gosse NJ, Xiao T, Chi NC, Asakawa K, Kawakami K, Baier H. PMID: 17369834.
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PubMed Mentions:
186 Fields:
Translation:
HumansAnimalsCells
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Molecular determinants of responses to myocardial ischemia/reperfusion injury: focus on hypoxia-inducible and heat shock factors. Cardiovasc Res. 2004 Feb 15; 61(3):437-47.
Chi NC, Karliner JS. PMID: 14962475.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3. Development. 2004 Feb; 131(4):829-37.
Milewski RC, Chi NC, Li J, Brown C, Lu MM, Epstein JA. PMID: 14736747.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Getting your Pax straight: Pax proteins in development and disease. Trends Genet. 2002 Jan; 18(1):41-7.
Chi N, Epstein JA. PMID: 11750700.
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PubMed Mentions:
144 Fields:
Translation:
HumansAnimals
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Sequence and characterization of cytoplasmic nuclear protein import factor p97. J Cell Biol. 1995 Jul; 130(2):265-74.
Chi NC, Adam EJ, Adam SA. PMID: 7615630; PMCID: PMC2199936.
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PubMed Mentions:
121 Fields:
Translation:
AnimalsCells
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Cytoplasmic factors in NLS-mediated targeting to the nuclear pore complex. Cold Spring Harb Symp Quant Biol. 1995; 60:687-94.
Adam SA, Adam EJ, Chi NC, Visser GD. PMID: 8824443.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells