Qingfei Jiang

Title(s)Assistant Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-9072-8032 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego, San Diego, CAPostdoctoral Fellowship01/2015Stem Cell
    University of Southern California, Los Angeles, CAPh.D12/2009Chemistry
    Hope College, Holland, MIB.S.08/2003Biology and Biochemistry
    United World Collage of Adriatic, ItalyI.B.01/2000
    Collapse Awards and Honors
    California Institute for Regenerative Medicine2011  - 2013Training Fellowship Interdisciplinary Stem Cell Training Program II

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Elucidate the Role of RNA Editing in Acute T-cell Lymphoblastic Leukemia Initiating Cells
    NCI R01Apr 1, 2024 - Mar 31, 2029
    Role: PI
    NCI R03Jan 1, 2024 - Dec 31, 2026
    Role: PI
    Targeting RNA modifications in pediatric leukemia
    Leukemia Research Foundation New Investigator AwardJul 1, 2023 - Jun 30, 2025
    Role: PI
    Elucidate the Role of RNA Editing in Acute T-cell Lymphoblastic Leukemia Initiating Cells
    American Society of Hematology Bridge AwardJul 1, 2023 - Jun 30, 2024
    Role: PI
    Regulating leukemia initiating cells in relapsed and refractory T-cell lymphoblastic Leukemia.
    Hartwell Foundation Individual Biomedical Research AwardMay 1, 2021 - Apr 30, 2024
    Role: PI
    Investigating the role of epitranscriptomic A-to-I RNA editing in T-cell acute lymphoblastic leukemia
    NIH K22CA229606Sep 1, 2019 - Aug 31, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. RNA editing regulates host immune response and T cell homeostasis in SARS-CoV-2 infection. PLoS One. 2024; 19(8):e0307450. Huang M, Mark A, Pham J, Vera K, Saravia-Butler AM, Beheshti A, Jiang Q, Fisch KM. PMID: 39178184; PMCID: PMC11343423.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Protocol for in vitro co-culture assay for rapid expansion of human T cell acute lymphoblastic leukemia. STAR Protoc. 2024 Jun 21; 5(2):103103. Rivera M, Lim CE, Jiang Q. PMID: 38829737; PMCID: PMC11179097.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia. Exp Cell Res. 2024 Apr 15; 437(2):114015. Enlund S, Sinha I, Neofytou C, Amor AR, Papadakis K, Nilsson A, Jiang Q, Hermanson O, Holm F. PMID: 38561062.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing. Cell Rep. 2024 Feb 27; 43(2):113704. Rivera M, Zhang H, Pham J, Isquith J, Zhou QJ, Balaian L, Sasik R, Enlund S, Mark A, Ma W, Holm F, Fisch KM, Kuo DJ, Jamieson C, Jiang Q. PMID: 38265938; PMCID: PMC10962356.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Reversal of malignant ADAR1 splice isoform switching with Rebecsinib. Cell Stem Cell. 2023 03 02; 30(3):250-263.e6. Crews LA, Ma W, Ladel L, Pham J, Balaian L, Steel SK, Mondala PK, Diep RH, Wu CN, Mason CN, van der Werf I, Oliver I, Reynoso E, Pineda G, Whisenant TC, Wentworth P, La Clair JJ, Jiang Q, Burkart MD, Jamieson CHM. PMID: 36803553; PMCID: PMC10134781.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    6. Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia. EJHaem. 2023 Feb; 4(1):115-124. Enlund S, Sinha I, Amor AR, Fard SS, Tamm EP, Jiang Q, Lundin V, Nilsson A, Holm F. PMID: 36819185; PMCID: PMC9928657.
      View in: PubMed   Mentions: 1  
    7. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Rep. 2021 01 26; 34(4):108670. Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, He Y, Mondala P, Oliver I, Pham J, Ma W, Reynoso E, Ali S, Morris IJ, Diep R, Nasamran C, Xu G, Sasik R, Rosenthal SB, Birmingham A, Coso S, Pineda G, Crews L, Donohoe ME, Venter JC, Whisenant T, Mesa RA, Alexandrov LB, Fisch KM, Jamieson C. PMID: 33503434; PMCID: PMC8477897.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    8. A-to-I RNA editing in leukemia stem cells - set ADAR1 on the radar. Oncotarget. 2019 Oct 22; 10(58):6047-6048. Jiang Q, Diep R, Jamieson C. PMID: 31692993; PMCID: PMC6817451.
      View in: PubMed   Mentions: 1     Fields:    
    9. Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation. Cancer Cell. 2019 01 14; 35(1):81-94.e7. Jiang Q, Isquith J, Zipeto MA, Diep RH, Pham J, Delos Santos N, Reynoso E, Chau J, Leu H, Lazzari E, Melese E, Ma W, Fang R, Minden M, Morris S, Ren B, Pineda G, Holm F, Jamieson C. PMID: 30612940; PMCID: PMC6333511.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    10. BET'ing on Dual JAK/BET Inhibition as a Therapeutic Strategy for Myeloproliferative Neoplasms. Cancer Cell. 2018 01 08; 33(1):3-5. Jiang Q, Jamieson C. PMID: 29316431.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    11. Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma. Nat Commun. 2017 12 04; 8(1):1922. Lazzari E, Mondala PK, Santos ND, Miller AC, Pineda G, Jiang Q, Leu H, Ali SA, Ganesan AP, Wu CN, Costello C, Minden M, Chiaramonte R, Stewart AK, Crews LA, Jamieson CHM. PMID: 29203771; PMCID: PMC5715072.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    12. RNA editing-dependent epitranscriptome diversity in cancer stem cells. Nat Rev Cancer. 2017 06; 17(6):381-392. Jiang Q, Crews LA, Holm F, Jamieson CHM. PMID: 28416802; PMCID: PMC5665169.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    13. ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell. 2016 08 04; 19(2):177-191. Zipeto MA, Court AC, Sadarangani A, Delos Santos NP, Balaian L, Chun HJ, Pineda G, Morris SR, Mason CN, Geron I, Barrett C, Goff DJ, Wall R, Pellecchia M, Minden M, Frazer KA, Marra MA, Crews LA, Jiang Q, Jamieson CHM. PMID: 27292188; PMCID: PMC4975616.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    14. RNA rewriting, recoding, and rewiring in human disease. Trends Mol Med. 2015 Sep; 21(9):549-59. Zipeto MA, Jiang Q, Melese E, Jamieson CH. PMID: 26259769.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    15. An RNA editing fingerprint of cancer stem cell reprogramming. J Transl Med. 2015 Feb 12; 13:52. Crews LA, Jiang Q, Zipeto MA, Lazzari E, Court AC, Ali S, Barrett CL, Frazer KA, Jamieson CH. PMID: 25889244; PMCID: PMC4341880.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    16. ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):1041-6. Jiang Q, Crews LA, Barrett CL, Chun HJ, Court AC, Isquith JM, Zipeto MA, Goff DJ, Minden M, Sadarangani A, Rusert JM, Dao KH, Morris SR, Goldstein LS, Marra MA, Frazer KA, Jamieson CH. PMID: 23275297; PMCID: PMC3549099.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    17. NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. PLoS One. 2012; 7(6):e39725. Ma W, Gutierrez A, Goff DJ, Geron I, Sadarangani A, Jamieson CA, Court AC, Shih AY, Jiang Q, Wu CC, Li K, Smith KM, Crews LA, Gibson NW, Deichaite I, Morris SR, Wei P, Carson DA, Look AT, Jamieson CH. PMID: 22768113; PMCID: PMC3387267.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    18. A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V. Crit Rev Biochem Mol Biol. 2010 Jun; 45(3):171-84. Patel M, Jiang Q, Woodgate R, Cox MM, Goodman MF. PMID: 20441441; PMCID: PMC2874081.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    19. The active form of DNA polymerase V is UmuD'(2)C-RecA-ATP. Nature. 2009 Jul 16; 460(7253):359-63. Jiang Q, Karata K, Woodgate R, Cox MM, Goodman MF. PMID: 19606142; PMCID: PMC2731490.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    20. Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chem Res Toxicol. 2008 Oct; 21(10):1983-90. Minko IG, Yamanaka K, Kozekov ID, Kozekova A, Indiani C, O'Donnell ME, Jiang Q, Goodman MF, Rizzo CJ, Lloyd RS. PMID: 18788757; PMCID: PMC2673917.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    21. Steric and electrostatic effects in DNA synthesis by the SOS-induced DNA polymerases II and IV of Escherichia coli. Biochemistry. 2007 Dec 04; 46(48):13874-81. Silverman AP, Jiang Q, Goodman MF, Kool ET. PMID: 17988102; PMCID: PMC2555966.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    22. Purification and characterization of Escherichia coli DNA polymerase V. Methods Enzymol. 2006; 408:378-90. Schlacher K, Jiang Q, Woodgate R, Goodman MF. PMID: 16793381.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
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