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Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia. bioRxiv. 2023 Dec 29.
Spinler K, Hamilton M, Bajaj J, Shima Y, Diaz E, Kritzik M, Reya T. PMID: 38234720; PMCID: PMC10793452.
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Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer. Cancer Cell. 2023 11 13; 41(11):1989-2005.e9.
Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T. PMID: 37802055; PMCID: PMC10836835.
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Animals
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A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia. Nat Commun. 2020 11 26; 11(1):5998.
Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T. PMID: 33243988; PMCID: PMC7691523.
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5 Fields:
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HumansAnimalsCells
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A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019 04 18; 177(3):572-586.e22.
Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. PMID: 30955884; PMCID: PMC6711371.
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61 Fields:
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HumansAnimalsCells
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Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016 06 16; 534(7607):407-411.
Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T. PMID: 27281208; PMCID: PMC4998062.
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76 Fields:
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HumansAnimalsCells
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Musashi signaling in stem cells and cancer. Annu Rev Cell Dev Biol. 2015; 31:249-67.
Fox RG, Park FD, Koechlein CS, Kritzik M, Reya T. PMID: 26566113.
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59 Fields:
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AnimalsCells
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Wnt signaling in normal and malignant hematopoiesis. Cold Spring Harb Perspect Biol. 2013 Feb 01; 5(2).
Lento W, Congdon K, Voermans C, Kritzik M, Reya T. PMID: 23378582; PMCID: PMC3552513.
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67 Fields:
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HumansAnimalsCells
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Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation. Endocrine. 2010 Apr; 37(2):312-21.
Kritzik MR, Lago CU, Kayali AG, Arnaud-Dabernat S, Liu G, Zhang YQ, Hua H, Fox HS, Sarvetnick NE. PMID: 20960269; PMCID: PMC4288843.
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1 Fields:
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AnimalsCells
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Nodal and lefty signaling regulates the growth of pancreatic cells. Dev Dyn. 2008 May; 237(5):1255-67.
Zhang YQ, Sterling L, Stotland A, Hua H, Kritzik M, Sarvetnick N. PMID: 18393305; PMCID: PMC4288850.
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12 Fields:
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AnimalsCells
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FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells. Diabetes. 2007 Jan; 56(1):96-106.
Arnaud-Dabernat S, Kritzik M, Kayali AG, Zhang YQ, Liu G, Ungles C, Sarvetnick N. PMID: 17192470.
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18 Fields:
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AnimalsCells
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PYY in the expanding pancreatic epithelium. Endocrine. 2006 Aug; 30(1):103-12.
Liu G, Arnaud-Dabernat S, Kritzik MR, Kayali AG, Zhang YQ, Sarvetnick N. PMID: 17185798.
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5 Fields:
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AnimalsCells
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BMP4 regulates pancreatic progenitor cell expansion through Id2. J Biol Chem. 2006 May 12; 281(19):13574-13580.
Hua H, Zhang YQ, Dabernat S, Kritzik M, Dietz D, Sterling L, Sarvetnick N. PMID: 16547003.
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49 Fields:
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AnimalsCells
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Growth factor-induced signaling of the pancreatic epithelium. J Endocrinol. 2005 Apr; 185(1):45-56.
Kayali AG, Stotland A, Gunst KV, Kritzik M, Liu G, Dabernat S, Zhang YQ, Wu W, Sarvetnick N. PMID: 15817826.
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4 Fields:
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AnimalsCells
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Identification and expansion of pancreatic stem/progenitor cells. J Cell Mol Med. 2005 Apr-Jun; 9(2):331-44.
Zhang YQ, Kritzik M, Sarvetnick N. PMID: 15963253; PMCID: PMC6740110.
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18 Fields:
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HumansAnimalsCells
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Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells. Diabetes. 2004 Aug; 53(8):2024-33.
Zhang YQ, Cleary MM, Si Y, Liu G, Eto Y, Kritzik M, Dabernat S, Kayali AG, Sarvetnick N. PMID: 15277382.
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29 Fields:
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HumansAnimalsCells
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The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas. J Cell Biol. 2003 Nov 24; 163(4):859-69.
Kayali AG, Van Gunst K, Campbell IL, Stotland A, Kritzik M, Liu G, Flodström-Tullberg M, Zhang YQ, Sarvetnick N. PMID: 14638861; PMCID: PMC2173676.
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40 Fields:
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AnimalsCells
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Allele-dependent transcriptional regulation of the human integrin alpha2 gene. Blood. 2001 Mar 15; 97(6):1721-6.
Jacquelin B, Tarantino MD, Kritzik M, Rozenshteyn D, Koziol JA, Nurden AT, Kunicki TJ. PMID: 11238113.
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12 Fields:
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HumansCells
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Transcription factor expression during pancreatic islet regeneration. Mol Cell Endocrinol. 2000 Jun; 164(1-2):99-107.
Kritzik MR, Krahl T, Good A, Krakowski M, St-Onge L, Gruss P, Wright C, Sarvetnick N. PMID: 11026562.
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13 Fields:
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AnimalsCells
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Expression of ErbB receptors during pancreatic islet development and regrowth. J Endocrinol. 2000 Apr; 165(1):67-77.
Kritzik MR, Krahl T, Good A, Gu D, Lai C, Fox H, Sarvetnick N. PMID: 10750037.
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18 Fields:
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Animals
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PDX-1 and Msx-2 expression in the regenerating and developing pancreas. J Endocrinol. 1999 Dec; 163(3):523-30.
Kritzik MR, Jones E, Chen Z, Krakowski M, Krahl T, Good A, Wright C, Fox H, Sarvetnick N. PMID: 10588826.
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23 Fields:
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AnimalsCells
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Transgenic expression of epidermal growth factor and keratinocyte growth factor in beta-cells results in substantial morphological changes. J Endocrinol. 1999 Aug; 162(2):167-75.
Krakowski ML, Kritzik MR, Jones EM, Krahl T, Lee J, Arnush M, Gu D, Mroczkowski B, Sarvetnick N. PMID: 10425454.
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16 Fields:
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HumansAnimals
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Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells. Am J Pathol. 1999 Mar; 154(3):683-91.
Krakowski ML, Kritzik MR, Jones EM, Krahl T, Lee J, Arnush M, Gu D, Sarvetnick N. PMID: 10079246; PMCID: PMC1866416.
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26 Fields:
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AnimalsCells
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Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood. 1998 Oct 01; 92(7):2382-8.
Kritzik M, Savage B, Nugent DJ, Santoso S, Ruggeri ZM, Kunicki TJ. PMID: 9746778.
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37 Fields:
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Humans
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Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence. Blood. 1997 Mar 15; 89(6):1939-43.
Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. PMID: 9058714.
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38 Fields:
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HumansCells