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Tatiana Kisseleva

Title(s)Associate Professor, Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Dr. Kisseleva was trained as a liver surgeon at Russian University of Friendship (Moscow, Russia). She finished her graduate studies at Christian-Albrecht University in Germany. As a postdoctoral fellow at Columbia University, Dr. Kisseleva studied signal transduction and transgenic mouse technologies. She recently joined the UC San Diego faculty as an Assistant Professor of Surgery. The major interest of Dr. Kisseleva's studies is the characterization of the origin of fibrogenic myofibroblasts and identification of novel targets for anti-fibrotic therapy.

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    Novel IL-23 inhibitor for the treatment of alcohol associated liver disease
    NIH U01AA029019Sep 20, 2020 - Aug 31, 2025
    Role: Co-Principal Investigator
    Fibrocytes regulate liver fibrosis
    NIH R01DK111866Feb 1, 2017 - Jan 31, 2021
    Role: Principal Investigator
    The Role of Portal Fibroblasts in Cholestatic Liver Fibrosis
    NIH R01DK101737Sep 15, 2014 - Aug 31, 2019
    Role: Principal Investigator
    The Role of IL-17 in Alcoholic Liver Disease and Cancer
    NIH U01AA022614Sep 1, 2014 - Jun 30, 2020
    Role: Principal Investigator
    Inactivation of Hepatic Stellate Cells During Reversal of Liver Fibrosis
    NIH R01DK099205May 15, 2014 - Apr 30, 2020
    Role: Principal Investigator
    The Role of Fibrocytes in Liver Fibrosis
    NIH R56DK088837Sep 24, 2012 - Aug 31, 2014
    Role: Principal Investigator
    Epigenetic Regulation of Alcoholic Liver Fibrosis
    NIH U01AA018663Sep 1, 2010 - Aug 31, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin avß6 upregulation following liver injury. J Clin Invest. 2021 Mar 16. Guillot A, Guerri L, Feng D, Kim SJ, Ait Ahmed Y, Paloczi J, He Y, Schuebel K, Dai S, Liu F, Pacher P, Kisseleva T, Qin X, Goldman D, Tacke F, Gao B. PMID: 33724957.
      View in: PubMed   Mentions:    Fields:    
    2. Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH). Hepatology. 2021 Feb 07. Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. PMID: 33550587.
      View in: PubMed   Mentions:    Fields:    
    3. Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury. Int J Biochem Cell Biol. 2021 Feb 01; 105933. Gratte FD, Pasic S, Abu Bakar NDB, Gogoi-Tiwari J, Liu X, Carlessi R, Kisseleva T, Brenner DA, Ramm GA, Olynyk JK, Tirnitz-Parker JEE. PMID: 33540107.
      View in: PubMed   Mentions:    Fields:    
    4. Immunopathobiology and therapeutic targets related to cytokines in liver diseases. Cell Mol Immunol. 2020 Nov 17. He Y, Hwang S, Ahmed YA, Feng D, Li N, Ribeiro M, Lafdil F, Kisseleva T, Szabo G, Gao B. PMID: 33203939.
      View in: PubMed   Mentions:    Fields:    
    5. Molecular and cellular mechanisms of liver fibrosis and its regression. Nat Rev Gastroenterol Hepatol. 2020 Oct 30. Kisseleva T, Brenner D. PMID: 33128017.
      View in: PubMed   Mentions: 3     Fields:    
    6. Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice. Arch Clin Biomed Res. 2020; 4(5):561-580. Jiang C, Iwaisako K, Cong M, Diggle K, Hassanein T, Brenner DA, Kisseleva T. PMID: 33210080.
      View in: PubMed   Mentions:
    7. Fructose stimulated de novo lipogenesis is promoted by inflammation. Nat Metab. 2020 10; 2(10):1034-1045. Todoric J, Di Caro G, Reibe S, Henstridge DC, Green CR, Vrbanac A, Ceteci F, Conche C, McNulty R, Shalapour S, Taniguchi K, Meikle PJ, Watrous JD, Moranchel R, Najhawan M, Jain M, Liu X, Kisseleva T, Diaz-Meco MT, Moscat J, Knight R, Greten FR, Lau LF, Metallo CM, Febbraio MA, Karin M. PMID: 32839596.
      View in: PubMed   Mentions:
    8. Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis. J Hepatol. 2021 Jan; 74(1):156-167. Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. PMID: 32763266.
      View in: PubMed   Mentions:    Fields:    
    9. Liver fibrosis: Pathophysiology and clinical implications. Wiley Interdiscip Rev Syst Biol Med. 2021 Jan; 13(1):e1499. Berumen J, Baglieri J, Kisseleva T, Mekeel K. PMID: 32713091.
      View in: PubMed   Mentions:    Fields:    
    10. Intestinal Virome in Patients With Alcoholic Hepatitis. Hepatology. 2020 Jul 12. Jiang L, Lang S, Duan Y, Zhang X, Gao B, Chopyk J, Schwanemann LK, Ventura-Cots M, Bataller R, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Ho SB, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Kisseleva T, Brenner DA, Tu XM, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 32654263.
      View in: PubMed   Mentions:    Fields:    
    11. Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2a-dependent mechanism. Mol Metab. 2020 Nov; 41:101039. Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS. PMID: 32534258.
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    12. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. PLoS One. 2020; 15(6):e0234038. Baeza-Raja B, Goodyear A, Liu X, Lam K, Yamamoto L, Li Y, Dodson GS, Takeuchi T, Kisseleva T, Brenner DA, Dabbagh K. PMID: 32492075.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. J Hepatol. 2020 Jul; 73(1):149-160. Arab JP, Cabrera D, Sehrawat TS, Jalan-Sakrikar N, Verma VK, Simonetto D, Cao S, Yaqoob U, Leon J, Freire M, Vargas JI, De Assuncao TM, Kwon JH, Guo Y, Kostallari E, Cai Q, Kisseleva T, Oh Y, Arrese M, Huebert RC, Shah VH. PMID: 32087348.
      View in: PubMed   Mentions: 3     Fields:    
    14. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020 02 13; 5(3). Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, Roberts A, Zheng B, Kumar V, Zengler K, Pizzo DP, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob GF, Kisseleva T. PMID: 32051339.
      View in: PubMed   Mentions: 2     Fields:    
    15. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Hepatol Commun. 2020 Apr; 4(4):606-626. Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, Brenner D, Kisseleva T. PMID: 32258954.
      View in: PubMed   Mentions:
    16. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. 2020 05; 158(6):1728-1744.e14. Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. PMID: 31982409.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    17. Mechanisms of liver fibrosis and its role in liver cancer. Exp Biol Med (Maywood). 2020 01; 245(2):96-108. Dhar D, Baglieri J, Kisseleva T, Brenner DA. PMID: 31924111.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    18. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. J Hepatol. 2020 May; 72(5):946-959. Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T. PMID: 31899206.
      View in: PubMed   Mentions: 5     Fields:    
    19. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metab. 2020 01 07; 31(1):189-206.e8. Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. PMID: 31761566.
      View in: PubMed   Mentions: 8     Fields:    
    20. The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease. Cell Metab. 2019 11 05; 30(5):850-852. Kisseleva T, Brenner DA. PMID: 31693880.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Coordinated development of the mouse extrahepatic bile duct: Implications for neonatal susceptibility to biliary injury. J Hepatol. 2020 01; 72(1):135-145. Khandekar G, Llewellyn J, Kriegermeier A, Waisbourd-Zinman O, Johnson N, Du Y, Giwa R, Liu X, Kisseleva T, Russo PA, Theise ND, Wells RG. PMID: 31562906.
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    22. Etiology-Specific Analysis of Hepatocellular Carcinoma Transcriptome Reveals Genetic Dysregulation in Pathways Implicated in Immunotherapy Efficacy. Cancers (Basel). 2019 Aug 30; 11(9). Li WT, Zou AE, Honda CO, Zheng H, Wang XQ, Kisseleva T, Chang EY, Ongkeko WM. PMID: 31480259.
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    23. Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis. JCI Insight. 2019 06 11; 5. Povero D, Pinatel EM, Leszczynska A, Goyal NP, Nishio T, Kim J, Kneiber D, de Araujo Horcel L, Eguchi A, Ordonez PM, Kisseleva T, Feldstein AE. PMID: 31184999.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    24. Molecular Genetic and Immune Functional Responses Distinguish Bone Marrow Mesenchymal Stromal Cells from Hepatic Stellate Cells. Stem Cells. 2019 08; 37(8):1075-1082. Chinnadurai R, Sands J, Rajan D, Liu X, Arafat D, Das R, Anania FA, Gibson G, Kisseleva T, Galipeau J. PMID: 31033095.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    25. Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. J Hepatol. 2019 09; 71(3):573-585. Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, Kisseleva T. PMID: 31071368.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    26. The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma. Int J Mol Sci. 2019 Apr 07; 20(7). Baglieri J, Brenner DA, Kisseleva T. PMID: 30959975.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    27. Combatting Fibrosis: Exosome-Based Therapies in the Regression of Liver Fibrosis. Hepatol Commun. 2019 Feb; 3(2):180-192. Chen L, Brenner DA, Kisseleva T. PMID: 30766956.
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    28. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Gastroenterology. 2019 03; 156(4):1156-1172.e6. Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA. PMID: 30445007.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    29. Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Ann Rheum Dis. 2018 11; 77(11):1636-1643. Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M. PMID: 30061164.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    30. New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature. 2018 08; 560(7717):198-203. Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M. PMID: 30046112.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    31. Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. Hepatology. 2018 09; 68(3):1070-1086. Lan T, Li C, Yang G, Sun Y, Zhuang L, Ou Y, Li H, Wang G, Kisseleva T, Brenner D, Guo J. PMID: 29572892.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    32. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight. 2017 12 21; 2(24). Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. PMID: 29263300.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    33. Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages. Circ Res. 2018 02 16; 122(4):583-590. Moore-Morris T, Cattaneo P, Guimarães-Camboa N, Bogomolovas J, Cedenilla M, Banerjee I, Ricote M, Kisseleva T, Zhang L, Gu Y, Dalton ND, Peterson KL, Chen J, Pucéat M, Evans SM. PMID: 29269349.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    34. Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nat Commun. 2017 12 12; 8(1):2137. Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, Du X, Sørensen HT, Vilstrup H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. PMID: 29233961.
      View in: PubMed   Mentions: 1     Fields:    
    35. Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma. Oncotarget. 2018 Jan 02; 9(1):224-235. Zheng H, Li P, Kwok JG, Korrapati A, Li WT, Qu Y, Wang XQ, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. PMID: 29416609.
      View in: PubMed   Mentions: 6     Fields:    
    36. Human hepatic stellate cell isolation and characterization. J Gastroenterol. 2018 01; 53(1):6-17. Shang L, Hosseini M, Liu X, Kisseleva T, Brenner DA. PMID: 29094206.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    37. The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. Hepatol Commun. 2017 12; 1(10):1043-1057. Xu J, Ma HY, Liang S, Sun M, Karin G, Koyama Y, Hu R, Quehenberger O, Davidson NO, Dennis EA, Kisseleva T, Brenner DA. PMID: 29404441.
      View in: PubMed   Mentions:
    38. Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nat Commun. 2017 10 16; 8(1):837. Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, Du X, Sørensen HT, Vilstrup H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. PMID: 29038503.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    39. Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice. Int J Mol Med. 2017 Aug; 40(2):454-464. Cong M, Zhao W, Liu T, Wang P, Fan X, Zhai Q, Bao X, Zhang D, You H, Kisseleva T, Brenner DA, Jia J, Zhuang H. PMID: 28627620.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    40. Alcohol-dysregulated microRNAs in hepatitis B virus-related hepatocellular carcinoma. PLoS One. 2017; 12(5):e0178547. Zheng H, Zou AE, Saad MA, Wang XQ, Kwok JG, Korrapati A, Li P, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. PMID: 28562643.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017 Jun 30; 127(7):2829-2841. Yang AM, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, Bluemel S, Hartmann P, Xu J, Koyama Y, Kisseleva T, Torralba MG, Moncera K, Beeri K, Chen CS, Freese K, Hellerbrand C, Lee SM, Hoffman HM, Mehal WZ, Garcia-Tsao G, Mutlu EA, Keshavarzian A, Brown GD, Ho SB, Bataller R, Stärkel P, Fouts DE, Schnabl B. PMID: 28530644.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    42. Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. Mol Ther Nucleic Acids. 2017 Jun 16; 7:314-323. Vollmann EH, Cao L, Amatucci A, Reynolds T, Hamann S, Dalkilic-Liddle I, Cameron TO, Hossbach M, Kauffman KJ, Mir FF, Anderson DG, Novobrantseva T, Koteliansky V, Kisseleva T, Brenner D, Duffield J, Burkly LC. PMID: 28624207.
      View in: PubMed   Mentions:
    43. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017 Apr 03; 127(4):1254-1270. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, Zhang M, Sun M, Cong M, Karin D, Taura K, Benner C, Heinz S, Bera T, Brenner DA, Kisseleva T. PMID: 28287406.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    44. The origin of fibrogenic myofibroblasts in fibrotic liver. Hepatology. 2017 03; 65(3):1039-1043. Kisseleva T. PMID: 27859502.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    45. p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer. Cancer Cell. 2016 10 10; 30(4):595-609. Duran A, Hernandez ED, Reina-Campos M, Castilla EA, Subramaniam S, Raghunandan S, Roberts LR, Kisseleva T, Karin M, Diaz-Meco MT, Moscat J. PMID: 27728806.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    46. Weight Loss Decreases Magnetic Resonance Elastography Estimated Liver Stiffness in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2017 03; 15(3):463-464. Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner D, Sirlin CB, Loomba R. PMID: 27712981.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    47. The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis. Differentiation. 2016 Sep; 92(3):84-92. Karin D, Koyama Y, Brenner D, Kisseleva T. PMID: 27591095.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    48. Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice. Age (Dordr). 2016 Aug; 38(4):291-302. Kim IH, Xu J, Liu X, Koyama Y, Ma HY, Diggle K, You YH, Schilling JM, Jeste D, Sharma K, Brenner DA, Kisseleva T. PMID: 27578257.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    49. The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease. Curr Pathobiol Rep. 2016 Mar; 4(1):27-35. Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, Tsukamoto H, Jeste DV, Grant I, Roberts AJ, Contet C, Geoffroy C, Zheng B, Brenner D, Kisseleva T. PMID: 27239399.
      View in: PubMed   Mentions:
    50. Promising Therapy Candidates for Liver Fibrosis. Front Physiol. 2016; 7:47. Wang P, Koyama Y, Liu X, Xu J, Ma HY, Liang S, Kim IH, Brenner DA, Kisseleva T. PMID: 26909046.
      View in: PubMed   Mentions:
    51. The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. Front Physiol. 2016; 7:17. Liang S, Kisseleva T, Brenner DA. PMID: 26869935.
      View in: PubMed   Mentions:
    52. Age and High-Fat Diet Effects on Glutamine Synthetase Immunoreactivity in Liver and Hippocampus and Recognition Memory in Mice. Curr Aging Sci. 2016; 9(4):301-309. Soontornniyomkij V, Kesby JP, Soontornniyomkij B, Kim JJ, Kisseleva T, Achim CL, Semenova S, Jeste DV. PMID: 27071478.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    53. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. PLoS One. 2015; 10(7):e0129743. Lan T, Kisseleva T, Brenner DA. PMID: 26222337.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    54. Reversibility of liver fibrosis. Clin Res Hepatol Gastroenterol. 2015 Sep; 39 Suppl 1:S60-3. Sun M, Kisseleva T. PMID: 26206574.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    55. Bone marrow-derived fibrocytes contribute to liver fibrosis. Exp Biol Med (Maywood). 2015 Jun; 240(6):691-700. Xu J, Kisseleva T. PMID: 25966982.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    56. Aging and liver disease. Curr Opin Gastroenterol. 2015 May; 31(3):184-91. Kim IH, Kisseleva T, Brenner DA. PMID: 25850346.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    57. Inhibition of type I natural killer T cells by retinoids or following sulfatide-mediated activation of type II natural killer T cells attenuates alcoholic liver disease in mice. Hepatology. 2015 Apr; 61(4):1357-69. Maricic I, Sheng H, Marrero I, Seki E, Kisseleva T, Chaturvedi S, Molle N, Mathews SA, Gao B, Kumar V. PMID: 25477000.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    58. Contribution of bone marrow-derived fibrocytes to liver fibrosis. Hepatobiliary Surg Nutr. 2015 Feb; 4(1):34-47. Xu J, Cong M, Park TJ, Scholten D, Brenner DA, Kisseleva T. PMID: 25713803.
      View in: PubMed   Mentions:
    59. New Approaches for Studying Alcoholic Liver Disease. Curr Pathobiol Rep. 2014 Dec; 2(4):171-183. Xu J, Liu X, Gao B, Karin M, Tsukamoto H, Brenner D, Kisseleva T. PMID: 26594598.
      View in: PubMed   Mentions:
    60. Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3297-305. Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T. PMID: 25074909.
      View in: PubMed   Mentions: 124     Fields:    Translation:AnimalsCells
    61. The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies. Front Pharmacol. 2014; 5:167. Xu J, Liu X, Koyama Y, Wang P, Lan T, Kim IG, Kim IH, Ma HY, Kisseleva T. PMID: 25100997.
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    62. Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest. 2014 Jul; 124(7):2921-34. Moore-Morris T, Guimarães-Camboa N, Banerjee I, Zambon AC, Kisseleva T, Velayoudon A, Stallcup WB, Gu Y, Dalton ND, Cedenilla M, Gomez-Amaro R, Zhou B, Brenner DA, Peterson KL, Chen J, Evans SM. PMID: 24937432.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
    63. Does interleukin-17 play the villain in nonalcoholic steatohepatitis? Hepatology. 2014 May; 59(5):1671-2. Kisseleva T. PMID: 24327572.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    64. Transcriptional repression of the transforming growth factor β (TGF-β) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor κB (NF-κB) p50 enhances TGF-β signaling in hepatic stellate cells. J Biol Chem. 2014 Mar 07; 289(10):7082-91. Liu C, Chen X, Yang L, Kisseleva T, Brenner DA, Seki E. PMID: 24448807.
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    65. Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Curr Pathobiol Rep. 2013 Sep; 1(3):209-214. Liu X, Xu J, Brenner DA, Kisseleva T. PMID: 24000319.
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    66. Evidence for a common progenitor of epithelial and mesenchymal components of the liver. Cell Death Differ. 2013 Aug; 20(8):1116-23. Conigliaro A, Amicone L, Costa V, De Santis Puzzonia M, Mancone C, Sacchetti B, Cicchini C, Garibaldi F, Brenner DA, Kisseleva T, Bianco P, Tripodi M. PMID: 23686136.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    67. Overexpression of endoglin modulates TGF-ß1-signalling pathways in a novel immortalized mouse hepatic stellate cell line. PLoS One. 2013; 8(2):e56116. Meurer SK, Alsamman M, Sahin H, Wasmuth HE, Kisseleva T, Brenner DA, Trautwein C, Weiskirchen R, Scholten D. PMID: 23437087.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    68. Inactivation of myofibroblasts during regression of liver fibrosis. . 2013 Feb 01; 12(3):381-2. Kisseleva T, Brenner DA. PMID: 23324345.
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    69. Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. Dig Liver Dis. 2013 Jun; 45(6):450-9. De Minicis S, Kisseleva T, Francis H, Baroni GS, Benedetti A, Brenner D, Alvaro D, Alpini G, Marzioni M. PMID: 23177172.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    70. Cell signals influencing hepatic fibrosis. Int J Hepatol. 2012; 2012:158547. Cong M, Iwaisako K, Jiang C, Kisseleva T. PMID: 22973518.
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    71. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology. 2012 Sep; 143(3):765-776.e3. Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y, Scholten D, Cong M, Iwaisako K, Liu X, Zhang M, Österreicher CH, Stickel F, Ley K, Brenner DA, Kisseleva T. PMID: 22687286.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    72. Origin of myofibroblasts in liver fibrosis. Fibrogenesis Tissue Repair. 2012; 5(Suppl 1):S17. Brenner DA, Kisseleva T, Scholten D, Paik YH, Iwaisako K, Inokuchi S, Schnabl B, Seki E, De Minicis S, Oesterreicher C, Taura K. PMID: 23259769.
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    73. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9448-53. Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. PMID: 22566629.
      View in: PubMed   Mentions: 232     Fields:    Translation:AnimalsCells
    74. What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis. J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:65-8. Iwaisako K, Brenner DA, Kisseleva T. PMID: 22320919.
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    75. The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. J Hepatol. 2012 Apr; 56(4):965-72. Kisseleva T, Brenner DA. PMID: 22173163.
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    76. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. Hepatol Res. 2011 Jul; 41(7):683-6. Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. PMID: 21711427.
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    77. Migration of fibrocytes in fibrogenic liver injury. Am J Pathol. 2011 Jul; 179(1):189-98. Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T. PMID: 21703401.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    78. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology. 2011 May; 53(5):1730-41. Paik YH, Iwaisako K, Seki E, Inokuchi S, Schnabl B, Osterreicher CH, Kisseleva T, Brenner DA. PMID: 21384410.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    79. Is it the end of the line for the EMT? Hepatology. 2011 May; 53(5):1433-5. Kisseleva T, Brenner DA. PMID: 21433040.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    80. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl). 2011 Oct; 89(10):997-1013. Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. PMID: 21499735.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    81. Anti-fibrogenic strategies and the regression of fibrosis. Best Pract Res Clin Gastroenterol. 2011 Apr; 25(2):305-17. Kisseleva T, Brenner DA. PMID: 21497747.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    82. Alteration of interferon-a/ß receptors in chronic hepatitis B patients. J Clin Immunol. 2011 Jun; 31(3):521-32. Meng F, Wang J, Ge J, Fan X, Wang B, Han L, Kisseleva T, Paik Y, Brenner DA, Wang K. PMID: 21445562.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    83. Recent advances in liver stem cell therapy. Curr Opin Gastroenterol. 2010 Jul; 26(4):395-402. Kisseleva T, Gigante E, Brenner DA. PMID: 20495456.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    84. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology. 2010 Sep; 139(3):987-98. Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T. PMID: 20546735.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    85. Hepatic progenitors for liver disease: current position. Stem Cells Cloning. 2010 Feb 25; 3:39-47. Conigliaro A, Brenner DA, Kisseleva T. PMID: 24198509.
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    86. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5. Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA. PMID: 19549522.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    87. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol. 2008 Dec; 173(6):1617-27. Lin SL, Kisseleva T, Brenner DA, Duffield JS. PMID: 19008372.
      View in: PubMed   Mentions: 326     Fields:    Translation:AnimalsCells
    88. NK and NKT cells in liver injury and fibrosis. Clin Immunol. 2009 Jan; 130(1):16-26. Notas G, Kisseleva T, Brenner D. PMID: 18823822.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    89. Fibrogenesis of parenchymal organs. Proc Am Thorac Soc. 2008 Apr 15; 5(3):338-42. Kisseleva T, Brenner DA. PMID: 18403330.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    90. Mechanisms of fibrogenesis. Exp Biol Med (Maywood). 2008 Feb; 233(2):109-22. Kisseleva T, Brenner DA. PMID: 18222966.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    91. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis. J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S73-8. Kisseleva T, Brenner DA. PMID: 17567473.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    92. NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer. J Clin Invest. 2006 Nov; 116(11):2955-63. Kisseleva T, Song L, Vorontchikhina M, Feirt N, Kitajewski J, Schindler C. PMID: 17053836.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    93. Hepatic stellate cells and the reversal of fibrosis. J Gastroenterol Hepatol. 2006 Oct; 21 Suppl 3:S84-7. Kisseleva T, Brenner DA. PMID: 16958681.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimals
    94. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Hepatol. 2006 Sep; 45(3):429-38. Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. PMID: 16846660.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    95. Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin. Int J Cancer. 2002 Mar 10; 98(2):210-5. Hansen HP, Matthey B, Barth S, Kisseleva T, Mokros T, Davies SJ, Beckett RP, Foelster-Holst R, Lange HH, Engert A, Lemke H. PMID: 11857410.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    96. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene. 2002 Feb 20; 285(1-2):1-24. Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW. PMID: 12039028.
      View in: PubMed   Mentions: 266     Fields:    Translation:HumansAnimalsCells
    97. CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha-converting enzyme. J Immunol. 2000 Dec 15; 165(12):6703-9. Hansen HP, Dietrich S, Kisseleva T, Mokros T, Mentlein R, Lange HH, Murphy G, Lemke H. PMID: 11120787.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    98. A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines. Int J Cancer. 1995 Nov 27; 63(5):750-6. Hansen HP, Kisseleva T, Kobarg J, Horn-Lohrens O, Havsteen B, Lemke H. PMID: 7591296.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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