Tatiana Kisseleva

Title(s)Professor, Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Dr. Kisseleva was trained as a liver surgeon at Russian University of Friendship (Moscow, Russia). She finished her graduate studies at Christian-Albrecht University in Germany. As a postdoctoral fellow at Columbia University, Dr. Kisseleva studied signal transduction and transgenic mouse technologies. She recently joined the UC San Diego faculty as an Assistant Professor of Surgery. The major interest of Dr. Kisseleva's studies is the characterization of the origin of fibrogenic myofibroblasts and identification of novel targets for anti-fibrotic therapy.

    Collapse Research 
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    The role of IL-17 signaling in alcohol-induced HCC
    NIH R01AA028550Aug 6, 2021 - May 31, 2026
    Role: Principal Investigator
    Novel IL-23 inhibitor for the treatment of alcohol associated liver disease
    NIH U01AA029019Sep 20, 2020 - Aug 31, 2025
    Role: Co-Principal Investigator
    Fibrocytes regulate liver fibrosis
    NIH R01DK111866Feb 1, 2017 - Jan 31, 2021
    Role: Principal Investigator
    The Role of Portal Fibroblasts in Cholestatic Liver Fibrosis
    NIH R01DK101737Sep 15, 2014 - Mar 31, 2026
    Role: Principal Investigator
    The Role of IL-17 in Alcoholic Liver Disease and Cancer
    NIH U01AA022614Sep 1, 2014 - Jun 30, 2020
    Role: Principal Investigator
    Inactivation of Hepatic Stellate Cells During Reversal of Liver Fibrosis
    NIH R01DK099205May 15, 2014 - Aug 31, 2026
    Role: Principal Investigator
    The Role of Fibrocytes in Liver Fibrosis
    NIH R56DK088837Sep 24, 2012 - Aug 31, 2014
    Role: Principal Investigator
    Epigenetic Regulation of Alcoholic Liver Fibrosis
    NIH U01AA018663Sep 1, 2010 - Aug 31, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Clinical Trial to Assess the Safety and Tolerability of Anti-IL 23 Monoclonal Antibody Guselkumab in Patients With Alcohol-Associated Liver Disease. Aliment Pharmacol Ther. 2025 Feb 14. Diaz LA, Morris S, Dave S, Kim SM, Sarik W, Richards L, Madamba E, Bettencourt R, Fulinara C, Pham T, Miller G, Carvalho-Gontijo Weber R, Momper JD, He F, Jain S, Jamieson C, Kisseleva T, Brenner D, Loomba R. PMID: 39949265.
      View in: PubMed   Mentions:    Fields:    
    2. Author Correction: FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature. 2025 Jan 31. Gu L, Zhu Y, Nandi SP, Lee M, Watari K, Bareng B, Ohira M, Liu Y, Sakane S, Carlessi R, Sauceda C, Dhar D, Ganguly S, Hosseini M, Teneche MG, Adams PD, Gonzalez DJ, Kisseleva T, Liver Cancer Collaborative, Tirnitz-Parker JEE, Simon MC, Alexandrov LB, Karin M. PMID: 39890899.
      View in: PubMed   Mentions:    Fields:    
    3. LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis. bioRxiv. 2025 Jan 18. Kim HY, Mizrahi O, Lee W, Rosenthal SB, Han C, Yee BA, Blue SM, Diaz J, Jonnalagadda J, Hokutan K, Jang H, Ma CT, Bobkov A, Sergienko E, Jackson MR, Stefanovic B, Kisseleva T, Yeo GW, Brenner DA. PMID: 39868246; PMCID: PMC11761402.
      View in: PubMed   Mentions:
    4. FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature. 2025 Jan; 637(8045):461-469. Gu L, Zhu Y, Nandi SP, Lee M, Watari K, Bareng B, Ohira M, Liu Y, Sakane S, Carlessi R, Sauceda C, Dhar D, Ganguly S, Hosseini M, Teneche MG, Adams PD, Gonzalez DJ, Kisseleva T, Liver Cancer Collaborative, Tirnitz-Parker JEE, Simon MC, Alexandrov LB, Karin M. PMID: 39743585.
      View in: PubMed   Mentions:    Fields:    
    5. Induction of MASH in three-dimensional bioprinted human liver tissue. PLoS One. 2024; 19(12):e0312615. Joshi V, Carter D, Chen AE, Murphy K, Higgins JW, Gurel M, Chilin Fuentes D, Rosenthal SB, Fisch KM, Kisseleva T, Brenner DA. PMID: 39775546; PMCID: PMC11684678.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Towards more consistent models and consensual terminology in preclinical research for steatotic liver disease. J Hepatol. 2024 Nov 22. Meijnikman AS, Fondevila MF, Arrese M, Kisseleva T, Bataller R, Schnabl B. PMID: 39581500.
      View in: PubMed   Mentions:    Fields:    
    7. Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease. J Hepatol. 2024 Nov 08. Kim HY, Rosenthal SB, Liu X, Miciano C, Hou X, Miller M, Buchanan J, Poirion OB, Chilin-Fuentes D, Han C, Housseini M, Carvalho-Gontijo Weber R, Sakane S, Lee W, Zhao H, Diggle K, Preissl S, Glass CK, Ren B, Wang A, Brenner DA, Kisseleva T. PMID: 39522884.
      View in: PubMed   Mentions:    Fields:    
    8. Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs. Hepatol Commun. 2024 Nov 01; 8(11). Cong M, Carvalho Gontijo Weber R, Sakane S, Zhang V, Jiang C, Taura K, Kodama Y, DeMinicis S, Ganguly S, Brafman D, Chien S, Kramer M, Lupher M, Brenner DA, Xu J, Kisseleva T. PMID: 39761005; PMCID: PMC11495776.
      View in: PubMed   Mentions:    Fields:    
    9. HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis. Sci Transl Med. 2024 Sep 11; 16(764):eadi0284. Jeelani I, Moon JS, da Cunha FF, Nasamran CA, Jeon S, Zhang X, Bandyopadhyay GK, Dobaczewska K, Mikulski Z, Hosseini M, Liu X, Kisseleva T, Brenner DA, Singh S, Loomba R, Kim M, Lee YS. PMID: 39259813; PMCID: PMC11665927.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2405746121. Ganguly S, Rosenthal SB, Ishizuka K, Troutman TD, Rohm TV, Khader N, Aleman-Muench G, Sano Y, Archilei S, Soroosh P, Olefsky JM, Feldstein AE, Kisseleva T, Loomba R, Glass CK, Brenner DA, Dhar D. PMID: 39172787; PMCID: PMC11363294.
      View in: PubMed   Mentions: 1     Fields:    
    11. Protocol to generate human liver spheroids to study liver fibrosis induced by metabolic stress. STAR Protoc. 2024 Jun 21; 5(2):103111. Kim HY, Lee W, Liu X, Jang H, Sakane S, Carvalho-Gontijo Weber R, Diggle K, Kerk SA, Metallo CM, Kisseleva T, Brenner DA. PMID: 38833372; PMCID: PMC11179098.
      View in: PubMed   Mentions: 1     Fields:    
    12. TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis. Cell Metab. 2024 May 07; 36(5):1030-1043.e7. Isaac R, Bandyopadhyay G, Rohm TV, Kang S, Wang J, Pokhrel N, Sakane S, Zapata R, Libster AM, Vinik Y, Berhan A, Kisseleva T, Borok Z, Zick Y, Telese F, Webster NJG, Olefsky JM. PMID: 38670107; PMCID: PMC11113091.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression. Biomolecules. 2024 Mar 27; 14(4). Osna NA, Tikhanovich I, Ortega-Ribera M, Mueller S, Zheng C, Mueller J, Li S, Sakane S, Weber RCG, Kim HY, Lee W, Ganguly S, Kimura Y, Liu X, Dhar D, Diggle K, Brenner DA, Kisseleva T, Attal N, McKillop IH, Chokshi S, Mahato R, Rasineni K, Szabo G, Kharbanda KK. PMID: 38672422; PMCID: PMC11048648.
      View in: PubMed   Mentions: 2     Fields:    
    14. SREBP Regulation of Lipid Metabolism in Liver Disease, and Therapeutic Strategies. Biomedicines. 2023 Dec 12; 11(12). Li N, Li X, Ding Y, Liu X, Diggle K, Kisseleva T, Brenner DA. PMID: 38137501; PMCID: PMC10740981.
      View in: PubMed   Mentions: 12  
    15. The Origin and Fate of Liver Myofibroblasts. Cell Mol Gastroenterol Hepatol. 2024; 17(1):93-106. Kim HY, Sakane S, Eguileor A, Carvalho Gontijo Weber R, Lee W, Liu X, Lam K, Ishizuka K, Rosenthal SB, Diggle K, Brenner DA, Kisseleva T. PMID: 37743012; PMCID: PMC10665929.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers. STAR Protoc. 2023 Sep 15; 4(3):102391. Liu X, Lam K, Zhao H, Sakane S, Kim HY, Eguileor A, Diggle K, Wu S, Gontijo Weber RC, Soroosh P, Hosseini M, Mekeel K, Brenner DA, Kisseleva T. PMID: 37405925; PMCID: PMC10345194.
      View in: PubMed   Mentions: 1     Fields:    
    17. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metab. 2023 06 06; 35(6):1009-1021.e9. Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel AR, Simon MC, Karin M. PMID: 37084733; PMCID: PMC10430883.
      View in: PubMed   Mentions: 5     Fields:    
    18. Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease. Cell Host Microbe. 2023 03 08; 31(3):389-404.e7. Zeng S, Rosati E, Saggau C, Messner B, Chu H, Duan Y, Hartmann P, Wang Y, Ma S, Huang WJM, Lee J, Lee SM, Carvalho-Gontijo R, Zhang V, Hoffmann JP, Kolls JK, Raz E, Brenner DA, Kisseleva T, LeibundGut-Landmann S, Bacher P, Stärkel P, Schnabl B. PMID: 36893735; PMCID: PMC10039706.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. IgY antibodies against cytolysin reduce ethanol-induced liver disease in mice. Hepatology. 2023 07 01; 78(1):295-306. Cabré N, Hartmann P, Llorente C, Kouno T, Wang Y, Zeng S, Kim HY, Zhang X, Kisseleva T, Iyer S, Kudumala S, Schnabl B. PMID: 36811393; PMCID: PMC10293100.
      View in: PubMed   Mentions: 5     Fields:    
    20. An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis. Sci Transl Med. 2023 01 04; 15(677):eadd3949. Wang S, Li K, Pickholz E, Dobie R, Matchett KP, Henderson NC, Carrico C, Driver I, Borch Jensen M, Chen L, Petitjean M, Bhattacharya D, Fiel MI, Liu X, Kisseleva T, Alon U, Adler M, Medzhitov R, Friedman SL. PMID: 36599008; PMCID: PMC10686705.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    21. Human Hepatic Stellate Cells: Isolation and Characterization. Methods Mol Biol. 2023; 2669:221-232. Liu X, Brenner DA, Kisseleva T. PMID: 37247063.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury. Biology (Basel). 2022 Oct 28; 11(11). Nishio T, Koyama Y, Fuji H, Ishizuka K, Iwaisako K, Taura K, Hatano E, Brenner DA, Kisseleva T. PMID: 36358290; PMCID: PMC9687690.
      View in: PubMed   Mentions: 2  
    23. Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Semin Liver Dis. 2022 08; 42(3):233-249. Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. PMID: 36001995; PMCID: PMC9662188.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    24. Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis. Cell Metab. 2022 08 02; 34(8):1201-1213.e5. Gao H, Jin Z, Bandyopadhyay G, Wang G, Zhang D, Rocha KCE, Liu X, Zhao H, Kisseleva T, Brenner DA, Karin M, Ying W. PMID: 35921818; PMCID: PMC9365100.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    25. MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH. Cell Metab. 2022 07 05; 34(7):978-990.e4. Gao H, Jin Z, Bandyopadhyay G, Cunha E Rocha K, Liu X, Zhao H, Zhang D, Jouihan H, Pourshahian S, Kisseleva T, Brenner DA, Ying W, Olefsky JM. PMID: 35700738; PMCID: PMC9262870.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    26. Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway. J Biol Chem. 2022 07; 298(7):102056. Kouno T, Liu X, Zhao H, Kisseleva T, Cable EE, Schnabl B. PMID: 35605662; PMCID: PMC9214809.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis. Front Mol Biosci. 2021; 8:790032. Fuji H, Miller G, Nishio T, Koyama Y, Lam K, Zhang V, Loomba R, Brenner D, Kisseleva T. PMID: 34966784; PMCID: PMC8710774.
      View in: PubMed   Mentions: 5  
    28. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease. Nat Commun. 2021 12 09; 12(1):7172. Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, Hosseini M, Kisseleva T, Brenner DA, Bataller R, Ramachandran P, Karin M, Fu W, Schnabl B. PMID: 34887405; PMCID: PMC8660815.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    29. PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells. PLoS One. 2021; 16(12):e0260721. Rady B, Nishio T, Dhar D, Liu X, Erion M, Kisseleva T, Brenner DA, Pocai A. PMID: 34879108; PMCID: PMC8654208.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    30. Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. Stem Cells. 2021 12; 39(12):1701-1717. Pouyanfard S, Meshgin N, Cruz LS, Diggle K, Hashemi H, Pham TV, Fierro M, Tamayo P, Fanjul A, Kisseleva T, Kaufman DS. PMID: 34460131.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    31. Heterogeneity of HSCs in a Mouse Model of NASH. Hepatology. 2021 08; 74(2):667-685. Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. PMID: 33550587; PMCID: PMC8346581.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    32. Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Proc Natl Acad Sci U S A. 2021 07 20; 118(29). Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, Brenner DA, Kisseleva T. PMID: 34253615; PMCID: PMC8307749.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    33. Interleukin-17 in Liver Disease Pathogenesis. Semin Liver Dis. 2021 11; 41(4):507-515. Li N, Yamamoto G, Fuji H, Kisseleva T. PMID: 34130335.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    34. Nondegradable Collagen Increases Liver Fibrosis but Not Hepatocellular Carcinoma in Mice. Am J Pathol. 2021 09; 191(9):1564-1579. Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal SB, Dhar D, Su H, Cong M, Jia J, Hosseini M, Karin M, Kisseleva T, Brenner DA. PMID: 34119473; PMCID: PMC8406794.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    35. Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet. Cell Mol Gastroenterol Hepatol. 2021; 12(3):891-920. Ganguly S, Muench GA, Shang L, Rosenthal SB, Rahman G, Wang R, Wang Y, Kwon HC, Diomino AM, Kisseleva T, Soorosh P, Hosseini M, Knight R, Schnabl B, Brenner DA, Dhar D. PMID: 34062281; PMCID: PMC8342972.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    36. Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following liver injury. J Clin Invest. 2021 05 03; 131(9). Guillot A, Guerri L, Feng D, Kim SJ, Ahmed YA, Paloczi J, He Y, Schuebel K, Dai S, Liu F, Pacher P, Kisseleva T, Qin X, Goldman D, Tacke F, Gao B. PMID: 33724957; PMCID: PMC8087210.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    37. Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury. Int J Biochem Cell Biol. 2021 05; 134:105933. Gratte FD, Pasic S, Abu Bakar NDB, Gogoi-Tiwari J, Liu X, Carlessi R, Kisseleva T, Brenner DA, Ramm GA, Olynyk JK, Tirnitz-Parker JEE. PMID: 33540107.
      View in: PubMed   Mentions: 2     Fields:    
    38. Immunopathobiology and therapeutic targets related to cytokines in liver diseases. Cell Mol Immunol. 2021 01; 18(1):18-37. He Y, Hwang S, Ahmed YA, Feng D, Li N, Ribeiro M, Lafdil F, Kisseleva T, Szabo G, Gao B. PMID: 33203939; PMCID: PMC7853124.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    39. Molecular and cellular mechanisms of liver fibrosis and its regression. Nat Rev Gastroenterol Hepatol. 2021 03; 18(3):151-166. Kisseleva T, Brenner D. PMID: 33128017.
      View in: PubMed   Mentions: 523     Fields:    Translation:HumansCells
    40. Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice. Arch Clin Biomed Res. 2020; 4(5):561-580. Jiang C, Iwaisako K, Cong M, Diggle K, Hassanein T, Brenner DA, Kisseleva T. PMID: 33210080; PMCID: PMC7671588.
      View in: PubMed   Mentions: 5  
    41. Intestinal Virome in Patients With Alcoholic Hepatitis. Hepatology. 2020 12; 72(6):2182-2196. Jiang L, Lang S, Duan Y, Zhang X, Gao B, Chopyk J, Schwanemann LK, Ventura-Cots M, Bataller R, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Ho SB, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Kisseleva T, Brenner DA, Tu XM, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 32654263; PMCID: PMC8159727.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    42. Fructose stimulated de novo lipogenesis is promoted by inflammation. Nat Metab. 2020 10; 2(10):1034-1045. Todoric J, Di Caro G, Reibe S, Henstridge DC, Green CR, Vrbanac A, Ceteci F, Conche C, McNulty R, Shalapour S, Taniguchi K, Meikle PJ, Watrous JD, Moranchel R, Najhawan M, Jain M, Liu X, Kisseleva T, Diaz-Meco MT, Moscat J, Knight R, Greten FR, Lau LF, Metallo CM, Febbraio MA, Karin M. PMID: 32839596; PMCID: PMC8018782.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    43. Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis. J Hepatol. 2021 01; 74(1):156-167. Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. PMID: 32763266; PMCID: PMC7749849.
      View in: PubMed   Mentions: 190     Fields:    Translation:HumansAnimalsCells
    44. Liver fibrosis: Pathophysiology and clinical implications. WIREs Mech Dis. 2021 Jan; 13(1):e1499. Berumen J, Baglieri J, Kisseleva T, Mekeel K. PMID: 32713091; PMCID: PMC9479486.
      View in: PubMed   Mentions: 56     Fields:    
    45. Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism. Mol Metab. 2020 11; 41:101039. Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS. PMID: 32534258; PMCID: PMC7393408.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. PLoS One. 2020; 15(6):e0234038. Baeza-Raja B, Goodyear A, Liu X, Lam K, Yamamoto L, Li Y, Dodson GS, Takeuchi T, Kisseleva T, Brenner DA, Dabbagh K. PMID: 32492075; PMCID: PMC7269334.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    47. Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. J Hepatol. 2020 07; 73(1):149-160. Arab JP, Cabrera D, Sehrawat TS, Jalan-Sakrikar N, Verma VK, Simonetto D, Cao S, Yaqoob U, Leon J, Freire M, Vargas JI, De Assuncao TM, Kwon JH, Guo Y, Kostallari E, Cai Q, Kisseleva T, Oh Y, Arrese M, Huebert RC, Shah VH. PMID: 32087348; PMCID: PMC7305991.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    48. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020 02 13; 5(3). Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, Roberts A, Zheng B, Kumar V, Zengler K, Pizzo DP, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob GF, Kisseleva T. PMID: 32051339; PMCID: PMC7098802.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    49. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Hepatol Commun. 2020 Apr; 4(4):606-626. Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, Brenner D, Kisseleva T. PMID: 32258954; PMCID: PMC7109347.
      View in: PubMed   Mentions: 15     Fields:    
    50. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. 2020 05; 158(6):1728-1744.e14. Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. PMID: 31982409; PMCID: PMC7252905.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    51. Mechanisms of liver fibrosis and its role in liver cancer. Exp Biol Med (Maywood). 2020 01; 245(2):96-108. Dhar D, Baglieri J, Kisseleva T, Brenner DA. PMID: 31924111; PMCID: PMC7016420.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
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    116. Alteration of interferon-α/β receptors in chronic hepatitis B patients. J Clin Immunol. 2011 Jun; 31(3):521-32. Meng F, Wang J, Ge J, Fan X, Wang B, Han L, Kisseleva T, Paik Y, Brenner DA, Wang K. PMID: 21445562; PMCID: PMC4795458.
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    117. Recent advances in liver stem cell therapy. Curr Opin Gastroenterol. 2010 Jul; 26(4):395-402. Kisseleva T, Gigante E, Brenner DA. PMID: 20495456.
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    118. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology. 2010 Sep; 139(3):987-98. Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T. PMID: 20546735; PMCID: PMC2930026.
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    119. Hepatic progenitors for liver disease: current position. Stem Cells Cloning. 2010 Feb 25; 3:39-47. Conigliaro A, Brenner DA, Kisseleva T. PMID: 24198509; PMCID: PMC3781731.
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    120. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5. Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA. PMID: 19549522; PMCID: PMC2757473.
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    121. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol. 2008 Dec; 173(6):1617-27. Lin SL, Kisseleva T, Brenner DA, Duffield JS. PMID: 19008372; PMCID: PMC2626374.
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    122. NK and NKT cells in liver injury and fibrosis. Clin Immunol. 2009 Jan; 130(1):16-26. Notas G, Kisseleva T, Brenner D. PMID: 18823822.
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    123. Fibrogenesis of parenchymal organs. Proc Am Thorac Soc. 2008 Apr 15; 5(3):338-42. Kisseleva T, Brenner DA. PMID: 18403330; PMCID: PMC2645245.
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    124. Mechanisms of fibrogenesis. Exp Biol Med (Maywood). 2008 Feb; 233(2):109-22. Kisseleva T, Brenner DA. PMID: 18222966.
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    125. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis. J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S73-8. Kisseleva T, Brenner DA. PMID: 17567473.
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    126. NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer. J Clin Invest. 2006 Nov; 116(11):2955-63. Kisseleva T, Song L, Vorontchikhina M, Feirt N, Kitajewski J, Schindler C. PMID: 17053836; PMCID: PMC1616192.
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    127. Hepatic stellate cells and the reversal of fibrosis. J Gastroenterol Hepatol. 2006 Oct; 21 Suppl 3:S84-7. Kisseleva T, Brenner DA. PMID: 16958681.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimals
    128. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Hepatol. 2006 Sep; 45(3):429-38. Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. PMID: 16846660.
      View in: PubMed   Mentions: 201     Fields:    Translation:AnimalsCells
    129. Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin. Int J Cancer. 2002 Mar 10; 98(2):210-5. Hansen HP, Matthey B, Barth S, Kisseleva T, Mokros T, Davies SJ, Beckett RP, Foelster-Holst R, Lange HH, Engert A, Lemke H. PMID: 11857410.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    130. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene. 2002 Feb 20; 285(1-2):1-24. Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW. PMID: 12039028.
      View in: PubMed   Mentions: 372     Fields:    Translation:HumansAnimalsCells
    131. CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha-converting enzyme. J Immunol. 2000 Dec 15; 165(12):6703-9. Hansen HP, Dietrich S, Kisseleva T, Mokros T, Mentlein R, Lange HH, Murphy G, Lemke H. PMID: 11120787.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    132. A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines. Int J Cancer. 1995 Nov 27; 63(5):750-6. Hansen HP, Kisseleva T, Kobarg J, Horn-Lohrens O, Havsteen B, Lemke H. PMID: 7591296.
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