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The aldehyde dehydrogenase ALDH1B1 exerts antiviral effects through the aggregation of the adaptor MAVS. Sci Signal. 2024 01 09; 17(818):eadf8016.
Sun N, Cai Q, Zhang Y, Zhang RR, Jiang J, Yang H, Qin CF, Cheng G. PMID: 38194477.
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1 Fields:
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AnimalsCells
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Publisher Correction: Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome. Nature. 2023 Mar; 615(7953):E24.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, Kumar A, Baglieri J, Siruno J, Le M, Li Y, Dozier S, Nair A, Filliol A, Sinchai N, Rosenthal SB, Santini J, Metallo CM, Molina A, Schwabe RF, Lowy AM, Brenner D, Sun B, Karin M. PMID: 36882540; PMCID: PMC10033397.
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1 Fields:
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Regulation of DNA damage response by trimeric G-proteins. iScience. 2023 Feb 17; 26(2):105973.
Abd El-Hafeez AA, Sun N, Chakraborty A, Ear J, Roy S, Chamarthi P, Rajapakse N, Das S, Luker KE, Hazra TK, Luker GD, Ghosh P. PMID: 36756378; PMCID: PMC9900518.
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3
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Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome. Nature. 2022 10; 610(7931):366-372.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, Kumar A, Baglieri J, Siruno J, Le M, Li Y, Dozier S, Nair A, Filliol A, Sinchai N, Rosenthal SB, Santini J, Metallo CM, Molina A, Schwabe RF, Lowy AM, Brenner D, Sun B, Karin M. PMID: 36198801; PMCID: PMC9588640.
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33 Fields:
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AnimalsCells
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Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16394-16403.
Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. PMID: 31363053; PMCID: PMC6697900.
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18 Fields:
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HumansCells
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Single-Cell Imaging of Metastatic Potential of Cancer Cells. iScience. 2018 Dec 21; 10:53-65.
Midde K, Sun N, Rohena C, Joosen L, Dhillon H, Ghosh P. PMID: 30500482; PMCID: PMC6263091.
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8
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PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins. Sci Signal. 2018 06 19; 11(535).
Li L, Zhao H, Liu P, Li C, Quanquin N, Ji X, Sun N, Du P, Qin CF, Lu N, Cheng G. PMID: 29921658; PMCID: PMC6434931.
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55 Fields:
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HumansAnimalsCells
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Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple. Sci Signal. 2018 02 27; 11(519).
Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA, Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. PMID: 29487190; PMCID: PMC5862031.
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17 Fields:
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HumansCells
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A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin. Mol Biol Cell. 2017 Dec 01; 28(25):3709-3723.
Aznar N, Sun N, Dunkel Y, Ear J, Buschman MD, Ghosh P. PMID: 29021338; PMCID: PMC5706997.
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9 Fields:
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HumansCells
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Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin. Curr Protoc Chem Biol. 2016 Dec 07; 8(4):265-298.
Ghosh P, Aznar N, Swanson L, Lo IC, Lopez-Sanchez I, Ear J, Rohena C, Kalogriopoulos N, Joosen L, Dunkel Y, Sun N, Nguyen P, Bhandari D. PMID: 27925669; PMCID: PMC5154557.
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4 Fields:
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HumansAnimalsCells
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Determinants of substrate and cation transport in the human Na+/dicarboxylate cotransporter NaDC3. J Biol Chem. 2014 Jun 13; 289(24):16998-7008.
Schlessinger A, Sun NN, Colas C, Pajor AM. PMID: 24808185; PMCID: PMC4059142.
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15 Fields:
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HumansAnimalsCells
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Functional characterization of SdcF from Bacillus licheniformis, a homolog of the SLC13 Na⁺/dicarboxylate transporters. J Membr Biol. 2013 Sep; 246(9):705-15.
Pajor AM, Sun NN, Leung A. PMID: 23979173.
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6 Fields:
Translation:
Cells
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Nonsteroidal anti-inflammatory drugs and other anthranilic acids inhibit the Na(+)/dicarboxylate symporter from Staphylococcus aureus. Biochemistry. 2013 Apr 30; 52(17):2924-32.
Pajor AM, Sun NN. PMID: 23566164.
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PubMed Mentions:
8 Fields:
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HumansCells
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Role of neprilysin in airway inflammation induced by diesel exhaust emissions. Res Rep Health Eff Inst. 2011 Jun; (159):3-40.
Wong SS, Sun NN, Fastje CD, Witten ML, Lantz RC, Lu B, Sherrill DL, Gerard CJ, Burgess JL, HEI Health Review Committee. PMID: 21877416; PMCID: PMC4751866.
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PubMed Mentions:
6 Fields:
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HumansAnimalsCells
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Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function. Biochim Biophys Acta. 2011 Jun; 1808(6):1454-61.
Pajor AM, Sun NN, Joshi AD, Randolph KM. PMID: 21073858; PMCID: PMC3046213.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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Role of isoleucine-554 in lithium binding by the Na+/dicarboxylate cotransporter NaDC1. Biochemistry. 2010 Oct 19; 49(41):8937-43.
Pajor AM, Sun NN. PMID: 20845974; PMCID: PMC2956517.
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3 Fields:
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AnimalsCells
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Single nucleotide polymorphisms in the human Na+-dicarboxylate cotransporter affect transport activity and protein expression. Am J Physiol Renal Physiol. 2010 Oct; 299(4):F704-11.
Pajor AM, Sun NN. PMID: 20610529; PMCID: PMC2957249.
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PubMed Mentions:
15 Fields:
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HumansAnimalsCells
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Acute changes in sputum collected from exposed human subjects in mining conditions. Inhal Toxicol. 2010 May; 22(6):479-85.
Wong SS, Sun NN, Miller HB, Witten ML, Burgess JL. PMID: 20384431; PMCID: PMC4441302.
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PubMed Mentions:
2 Fields:
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HumansPHPublic Health
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In Vitro Pro-inflammatory Regulatory role of Substance P in Alveolar Macrophages and Type II Pneumocytes after JP-8 Exposure. J Immunotoxicol. 2007 Jan; 4(1):61-7.
Sun NN, Wong SS, Nardi C, Ostroff D, Witten ML, Lantz RC. PMID: 18958713.
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1 Fields:
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Neurogenic responses in rat lungs after nose-only exposure to diesel exhaust. Res Rep Health Eff Inst. 2005 Jan; (128):1-37; discussion 39-47.
Witten ML, Wong SS, Sun NN, Keith I, Kweon CB, Foster DE, Schauer JJ, Sherrill DL. PMID: 15916011.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Tachykinin substance P depletion by capsaicin exacerbates inflammatory response to sidestream cigarette smoke in rats. Toxicology. 2004 Sep 01; 201(1-3):39-50.
Sun NN, Wong SS, Keith I, Witten ML. PMID: 15297018.
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3 Fields:
Translation:
Animals
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Substance P and neutral endopeptidase in development of acute respiratory distress syndrome following fire smoke inhalation. Am J Physiol Lung Cell Mol Physiol. 2004 Oct; 287(4):L859-66.
Wong SS, Sun NN, Lantz RC, Witten ML. PMID: 15194566.
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9 Fields:
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HumansAnimals
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Inflammatory responses in mice sequentially exposed to JP-8 jet fuel and influenza virus. Toxicology. 2004 Apr 15; 197(2):139-47.
Wong SS, Hyde J, Sun NN, Lantz RC, Witten ML. PMID: 15003324.
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PubMed Mentions:
2 Fields:
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Animals
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Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line. Toxicol Ind Health. 2003 Oct; 19(7-10):157-63.
Sun NN, Fastje CD, Wong SS, Sheppard PR, Macdonald SJ, Ridenour G, Hyde JD, Witten ML. PMID: 15747776.
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PubMed Mentions:
3 Fields:
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HumansCellsPHPublic Health
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Tachykinin substance P signaling involved in diesel exhaust-induced bronchopulmonary neurogenic inflammation in rats. Arch Toxicol. 2003 Nov; 77(11):638-50.
Wong SS, Sun NN, Keith I, Kweon CB, Foster DE, Schauer JJ, Witten ML. PMID: 13680092.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Tissue-specific patterns of neurokinin-1 receptor (NK-1R) gene expression in mice exposed to sidestream cigarette smoke. Toxicol Ind Health. 2002 Oct; 18(9-10):435-44.
Wong SS, Sun NN, Lantz RC, Witten ML. PMID: 15222133.
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AnimalsCellsPHPublic Health
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Immunomodulatory effects of high-dose alpha-tocopherol acetate on mice subjected to sidestream cigarette smoke. Toxicology. 2002 Jun 14; 175(1-3):235-45.
Wang S, Sun NN, Zhang J, Watson RR, Witten ML. PMID: 12049851.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsPHPublic Health
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In vitro cytokine release from rat type II pneumocytes and alveolar macrophages following exposure to JP-8 jet fuel in co-culture. Toxicology. 2002 May 01; 173(3):211-9.
Wang S, Young RS, Sun NN, Witten ML. PMID: 11960674.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells