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Bernd Schnabl

Photo of Bernd Schnabl
Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
Emailbeschnabl@ucsd.edu
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    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    San Diego Digestive Diseases Research Center
    NIH P30DK120515Jul 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    The role of Enterococcus faecalis in alcoholic liver disease
    VA I01BX004594Oct 1, 2018 - Sep 30, 2022
    Role: Principal Investigator
    Microbiome as therapeutic target in alcoholic hepatitis
    NIH/NIAAA U01AA026939Sep 22, 2018 - Jun 30, 2023
    Role: Principal Investigator
    The Role of the Intestinal Mycobiome in Alcoholic Liver Disease
    NIH/NIAAA R01AA024726Apr 10, 2017 - Mar 31, 2022
    Role: Principal Investigator
    The Role of the Intestinal Mycobiome in Alcoholic Liver Disease
    NIH/NIAAA U01AA024726Apr 10, 2017 - Mar 31, 2022
    Role: Principal Investigator
    The Commensal Microflora Suppresses Liver Fibrosis
    VA I01BX002213Oct 1, 2014 - Sep 30, 2018
    Role: Principal Investigator
    Microbiome as Therapeutic Target in Alcoholic Hepatitis
    NIH U01AA021856Jun 1, 2013 - May 31, 2019
    Role: Principal Investigator
    Microbiome and intestinal innate immune response in alcoholic liver disease
    NIH/NIAAA R01AA020703Sep 25, 2011 - Jun 30, 2021
    Role: Principal Investigator
    Blocking toll-like receptor 4 signaling as therapy in hepatic fibrosis
    NIH/NIDDK K08DK081830Sep 30, 2009 - Jun 30, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity. Nature. 2025 Aug 20. Llorente C, Raya Tonetti F, Bruellman R, Brea R, Pell N, Hartmann P, Maccioni L, Han H, Cabré N, Liu J, Eguileor A, Fondevila MF, Meijnikman AS, Hsu CL, Alghafri A, Zhou R, Gao B, Duan Y, Zhang P, Febbraio MA, Taniguchi K, Newberry RD, Fouts DE, Brenner DA, Stärkel P, Karin M, Schnabl B. PMID: 40836099.
      View in: PubMed   Mentions:    Fields:    
    2. Microbiota in Alcohol-Associated Organ Damage. Am J Pathol. 2025 Jun 11. Harberts A, Schnabl B. PMID: 40513820.
      View in: PubMed   Mentions:
    3. Panose prevents acute-on-chronic liver failure by reducing bacterial infection in mice. J Clin Invest. 2025 Jul 15; 135(14). Li J, Xie S, Chen M, Hong C, Chen Y, Lyu F, Tang N, Chen T, Zhao L, Zou W, Peng H, Bao J, Gu P, Schnabl B, Chen J, Chen P. PMID: 40478727; PMCID: PMC12259250.
      View in: PubMed   Mentions:
    4. Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease. Cell Host Microbe. 2025 Jun 11; 33(6):957-972.e6. Yang Y, Duan Y, Lang S, Fondevila MF, Schöler D, Harberts A, Cabré N, Chen S, Shao Y, Vervier K, Miyamoto Y, Zhang X, Chu H, Yang L, Tan C, Eckmann L, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Stärkel P, Lawley TD, Schnabl B. PMID: 40441146; PMCID: PMC12162233.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Fecal carriage of multidrug-resistant organisms increases the risk of hepatic encephalopathy in patients with cirrhosis: insights from gut microbiota and metabolite features. Gut Pathog. 2025 May 16; 17(1):30. Wu PS, Lee PC, Chang TE, Hsieh YC, Huang CW, Lin CH, Huang YL, Lin YT, Huo TI, Schnabl B, Lee KC, Hou MC. PMID: 40380209; PMCID: PMC12085042.
      View in: PubMed   Mentions:
    6. Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease. J Clin Invest. 2025 Jul 01; 135(13). Cabré N, Fondevila MF, Wei W, Yamazaki T, Tonetti FR, Eguileor A, Garcia-Carbonell R, Meijnikman AS, Miyamoto Y, Mayo S, Wang Y, Zhang X, Trimbuch T, Lehnardt S, Eckmann L, Fouts DE, Llorente C, Tsukamoto H, Stärkel P, Schnabl B. PMID: 40359032; PMCID: PMC12208555.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Non-Alcoholic Beer Influences Glucose and Lipid Metabolism and Changes Body Composition in Healthy, Young, Male Adults. Nutrients. 2025 May 09; 17(10). Kreimeyer H, Sydor S, Buchholz L, Toskal C, Özcürümez M, Schnabl B, Syn WK, Sowa JP, Manka P, Canbay A. PMID: 40431365; PMCID: PMC12114185.
      View in: PubMed   Mentions:
    8. Insertion sequence-mediated phage resistance contributes to attenuated colonization of cytolytic Enterococcus faecalis variants in the gut. Microbiol Spectr. 2025 Apr 15; e0330324. Fujiki J, Nakamura T, Kreimeyer H, Llorente C, Fouts DE, Schnabl B. PMID: 40231830; PMCID: PMC12054073.
      View in: PubMed   Mentions: 2     Fields:    
    9. Unlocking the potential of the gut microbiome in liver regeneration: Benefits and mechanistic insights. Acta Pharm Sin B. 2025 Mar; 15(3):1715-1716. Wei W, Schnabl B. PMID: 40370569; PMCID: PMC12069235.
      View in: PubMed   Mentions:
    10. Metabolic dysfunction-associated steatotic liver disease and the gut microbiome: pathogenic insights and therapeutic innovations. J Clin Invest. 2025 Apr 01; 135(7). Schnabl B, Damman CJ, Carr RM. PMID: 40166938; PMCID: PMC11957707.
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    11. Faecal Cytolysin is Associated With Worse Survival in Patients With Primary Sclerosing Cholangitis. Liver Int. 2025 Apr; 45(4):e16181. Özdirik B, Berger H, Tonetti FR, Cabré N, Treichel N, Clavel T, Tacke F, Sigal M, Schnabl B. PMID: 40083245.
      View in: PubMed   Mentions:
    12. Faecalibacterium prausnitzii Is Associated with Disease Severity in MASLD but Its Supplementation Does Not Improve Diet-Induced Steatohepatitis in Mice. Microorganisms. 2025 Mar 18; 13(3). Münte E, Viebahn G, Khurana A, Fujiki J, Nakamura T, Lang S, Demir M, Schnabl B, Hartmann P. PMID: 40142567; PMCID: PMC11944644.
      View in: PubMed   Mentions: 3  
    13. Influence of Alcohol on the Intestinal Immune System. Alcohol Res. 2025; 45(1):03. Kreimeyer H, Llorente C, Schnabl B. PMID: 40151622; PMCID: PMC11913448.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Gram-positive probiotics improves acetaminophen-induced hepatotoxicity by inhibiting leucine and Hippo-YAP pathway. Cell Biosci. 2025 Mar 07; 15(1):32. Gao W, Wang G, Yuan H, Chen Y, Che J, Cheng Z, Chen L, Zhang L, Zhu Y, Liu X, Liu A, Yang Q, Cao P, Qian W, Huang W, Schnabl B, Yang L, Chu H. PMID: 40055814; PMCID: PMC11887100.
      View in: PubMed   Mentions:
    15. Peroxisome proliferator-activated receptor delta and liver diseases. Hepatol Commun. 2025 Feb 01; 9(2). Yamazaki T, Cable EE, Schnabl B. PMID: 39899669; PMCID: PMC12333746.
      View in: PubMed   Mentions:
    16. Origin, Function, and Implications of Intestinal and Hepatic Macrophages in the Pathogenesis of Alcohol-Associated Liver Disease. Cells. 2025 01 30; 14(3). Hu Y, Schnabl B, Stärkel P. PMID: 39936998; PMCID: PMC11816606.
      View in: PubMed   Mentions:
    17. Role of Intestinal Microbiome in Potentiating Inflammation and Predicting Outcomes in Alcohol-Associated Cirrhosis. Gastroenterol Clin North Am. 2025 Jun; 54(2):453-467. Støy S, Schnabl B. PMID: 40348498; PMCID: PMC12066832.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Modulating the microbiome in chronic liver diseases - current evidence on the role of fecal microbiota transplantation. Expert Rev Gastroenterol Hepatol. 2025 Jan; 19(1):53-64. Saha S, Schnabl B. PMID: 39760535; PMCID: PMC11882407.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Gut microbiota in treating inflammatory digestive diseases: Current challenges and therapeutic opportunities. Imeta. 2025 Feb; 4(1):e265. Shi Y, Chen Z, Fang T, Chen X, Deng Y, Qin H, Lian M, Shen J, Zong Y, Chu H, Hoebinger C, Guo H, Yuan Z, Zheng J, Zhou Y, Pan Y, Mendes BG, Lang S, Hendrikx T, Zeng S, Cao H, Yang L, Chen L, Chen P, Dai L, Wang H, Yin S, Zhu S, Ma X, Schnabl B, Chen H, Duan Y. PMID: 40027479; PMCID: PMC11865350.
      View in: PubMed   Mentions:
    20. Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis. Gut. 2024 Dec 10; 74(1):103-115. Kreimeyer H, Gonzalez CG, Fondevila MF, Hsu CL, Hartmann P, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Investigators A, Gonzalez DJ, Schnabl B. PMID: 39033024; PMCID: PMC11631684.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    21. Author Correction: Hepatic immune regulation and sex disparities. Nat Rev Gastroenterol Hepatol. 2024 Dec; 21(12):887. Burra P, Zanetto A, Schnabl B, Reiberger T, Montano-Loza AJ, Asselta R, Karlsen TH, Tacke F. PMID: 39390290.
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    22. Towards more consistent models and consensual terminology in preclinical research for steatotic liver disease. J Hepatol. 2025 Apr; 82(4):760-766. Meijnikman AS, Fondevila MF, Arrese M, Kisseleva T, Bataller R, Schnabl B. PMID: 39581500.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis among community-dwelling overweight and obese individuals in the USA. Gut. 2024 Nov 11; 73(12):2045-2053. Yang AH, Tincopa MA, Tavaglione F, Ajmera VH, Richards LM, Amangurbanova M, Butcher C, Hernandez C, Madamba E, Singh S, Bettencourt R, Schnabl B, Sirlin CB, Loomba R. PMID: 39117370.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    24. Noninvasive Monitoring of Steatotic Liver Disease in Western Diet-Fed Obese Mice Using Automated Ultrasound and Shear Wave Elastography. Liver Int. 2025 Apr; 45(4):e16141. Czernuszewicz TJ, Wang Y, Jiang L, Kim K, Mikulski Z, Aji AM, Rojas JD, Gessner RC, Schnabl B. PMID: 39523997; PMCID: PMC11903181.
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    25. Viral antibody response predicts morbidity and mortality in alcohol-associated hepatitis. Hepatology. 2025 Jul 01; 82(1):127-139. Hsu CL, Wang L, Maestri E, Jacob AR, Do WL, Mayo S, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Stärkel P, Bataller R, Investigators A, Wang XW, Schnabl B. PMID: 39325984; PMCID: PMC11932942.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis. Cell Metab. 2024 Oct 01; 36(10):2341-2354.e6. Zhang P, Liu J, Lee A, Tsaur I, Ohira M, Duong V, Vo N, Watari K, Su H, Kim JY, Gu L, Zhu M, Shalapour S, Hosseini M, Bandyopadhyay G, Zeng S, Llorente C, Zhao HN, Lamichhane S, Mohan S, Dorrestein PC, Olefsky JM, Schnabl B, Soroosh P, Karin M. PMID: 39317186; PMCID: PMC11631175.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    27. Hepatic immune regulation and sex disparities. Nat Rev Gastroenterol Hepatol. 2024 Dec; 21(12):869-884. Burra P, Zanetto A, Schnabl B, Reiberger T, Montano-Loza AJ, Asselta R, Karlsen TH, Tacke F. PMID: 39237606.
      View in: PubMed   Mentions:
    28. Fecal gelatinase does not predict mortality in patients with alcohol-associated hepatitis. Microb Cell. 2024; 11:328-338. Yang Y, Hartmann P, Schnabl B. PMID: 39206205; PMCID: PMC11350238.
      View in: PubMed   Mentions:
    29. Gut mycobiome alterations and implications for liver diseases. PLoS Pathog. 2024 Aug; 20(8):e1012377. Zeng S, Schnabl B. PMID: 39116092; PMCID: PMC11309506.
      View in: PubMed   Mentions:
    30. Relationship between updated MELD and prognosis in alcohol-associated hepatitis: Opportunities for more efficient trial design. Hepatol Commun. 2024 08 01; 8(8). Al-Karaghouli M, Ventura-Cots M, Wong YJ, Genesca J, Bosques F, Brown RS, Mathurin P, Louvet A, Shawcross D, Vargas V, Verna EC, Schnabl B, Caballeria J, Shah VJ, Kamath PS, Lucey MR, Garcia-Tsao G, Bataller R, Abraldes JG. PMID: 39082963; PMCID: PMC12333734.
      View in: PubMed   Mentions:
    31. Gut Bacteria in Alcohol-Associated Liver Disease. Clin Liver Dis. 2024 Nov; 28(4):663-679. Yang Y, Schnabl B. PMID: 39362714; PMCID: PMC11450261.
      View in: PubMed   Mentions: 4     Fields:    
    32. Endogenous ethanol production in health and disease. Nat Rev Gastroenterol Hepatol. 2024 Aug; 21(8):556-571. Meijnikman AS, Nieuwdorp M, Schnabl B. PMID: 38831008.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. Fecal Carriage of Multidrug-Resistant Organisms Increases the Risk of Hepatic Encephalopathy in Cirrhotic Patients: Insights from Gut Microbiota and Metabolite Features. Res Sq. 2024 May 07. Wu P, Lee PC, Chang TE, Hsieh YC, Chiou JJ, Lin CH, Huang YL, Lin YT, Huo TI, Schnabl B, Lee KC, Hou MC. PMID: 38766152; PMCID: PMC11100873.
      View in: PubMed   Mentions:
    34. PPAR Agonists in Primary Biliary Cholangitis. N Engl J Med. 2024 02 29; 390(9):855-858. Schnabl B. PMID: 38381666.
      View in: PubMed   Mentions:
    35. Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis. Hepatology. 2024 08 01; 80(2):403-417. Yamazaki T, Kouno T, Hsu CL, Hartmann P, Mayo S, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Schnabl B, AlcHepNet Investigators. PMID: 38377466; PMCID: PMC11268475.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    36. The role of the microbiome in liver disease. Curr Opin Gastroenterol. 2024 05 01; 40(3):134-142. Schöler D, Schnabl B. PMID: 38362864; PMCID: PMC10990783.
      View in: PubMed   Mentions:
    37. Fungal signature differentiates alcohol-associated liver disease from nonalcoholic fatty liver disease. Gut Microbes. 2024 Jan-Dec; 16(1):2307586. Viebahn G, Hartmann P, Lang S, Demir M, Zhang X, Fouts DE, Stärkel P, Schnabl B. PMID: 38298161; PMCID: PMC10841010.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Microbial Players in Primary Sclerosing Cholangitis: Current Evidence and Concepts. Cell Mol Gastroenterol Hepatol. 2024; 17(3):423-438. Özdirik B, Schnabl B. PMID: 38109970; PMCID: PMC10837305.
      View in: PubMed   Mentions:
    39. Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism. Cell Host Microbe. 2024 01 10; 32(1):48-62.e9. Li D, Chen Y, Wan M, Mei F, Wang F, Gu P, Zhang X, Wei R, Zeng Y, Zheng H, Chen B, Xiong Q, Xue T, Guan T, Guo J, Tian Y, Zeng LY, Liu Z, Yuan H, Yang L, Liu H, Dai L, Yu Y, Qiu Y, Wu P, Win S, Than TA, Wei R, Schnabl B, Kaplowitz N, Jiang Y, Ma Q, Chen P. PMID: 38056458.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    40. Development of a Quantitative PCR Method for Detecting Enterococcus faecalis Cytolysin in Human Stool Samples. Methods Protoc. 2023 Nov 08; 6(6). Cabré N, Yang Y, Wang Y, Schnabl B. PMID: 37987354; PMCID: PMC10660514.
      View in: PubMed   Mentions:
    41. Phage therapy: Targeting intestinal bacterial microbiota for the treatment of liver diseases. JHEP Rep. 2023 Dec; 5(12):100909. Fujiki J, Schnabl B. PMID: 37965159; PMCID: PMC10641246.
      View in: PubMed   Mentions:
    42. Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes. Nat Immunol. 2023 Nov; 24(11):1825-1838. Bennett H, Troutman TD, Zhou E, Spann NJ, Link VM, Seidman JS, Nickl CK, Abe Y, Sakai M, Pasillas MP, Marlman JM, Guzman C, Hosseini M, Schnabl B, Glass CK. PMID: 37735593; PMCID: PMC10602851.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    43. The arginine methyltransferase PRMT5 promotes mucosal defense in the intestine. Life Sci Alliance. 2023 11; 6(11). Hernandez JE, Llorente C, Ma S, Miyamoto KT, Sinha S, Steele S, Xiao Z, Lai CJ, Zuniga EI, Ghosh P, Schnabl B, Huang WJM. PMID: 37666668; PMCID: PMC10477432.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    44. A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis. Cell Mol Immunol. 2023 10; 20(10):1156-1170. Gu P, Liu R, Yang Q, Xie L, Wei R, Li J, Mei F, Chen T, Zeng Z, He Y, Zhou H, Peng H, Nandakumar KS, Chu H, Jiang Y, Gong W, Chen Y, Schnabl B, Chen P. PMID: 37553429; PMCID: PMC10541433.
      View in: PubMed   Mentions:
    45. Gut Microbiome-Centered Therapies for Alcohol-Associated Liver Disease. Semin Liver Dis. 2023 08; 43(3):311-322. Ranjbarian T, Schnabl B. PMID: 37527781.
      View in: PubMed   Mentions:
    46. Bile acid and nonalcoholic steatohepatitis: Molecular insights and therapeutic targets. J Adv Res. 2024 May; 59:173-187. Cheng Z, Chen Y, Schnabl B, Chu H, Yang L. PMID: 37356804; PMCID: PMC11081971.
      View in: PubMed   Mentions:
    47. The gut-liver axis and gut microbiota in health and liver disease. Nat Rev Microbiol. 2023 Nov; 21(11):719-733. Hsu CL, Schnabl B. PMID: 37316582; PMCID: PMC10794111.
      View in: PubMed   Mentions: 163     Fields:    Translation:Humans
    48. Intestinal clock modulates rhythmic hepatic metabolism. J Hepatol. 2023 09; 79(3):589-591. Fondevila MF, Schnabl B. PMID: 37290589.
      View in: PubMed   Mentions: 1     Fields:    
    49. Acute alcohol-associated hepatitis: Latest findings in non-invasive biomarkers and treatment. Liver Int. 2025 Mar; 45(3):e15608. Yamazaki T, Schnabl B. PMID: 37183549; PMCID: PMC10646153.
      View in: PubMed   Mentions:
    50. Fecal cytolysin does not predict disease severity in acutely decompensated cirrhosis and acute-on-chronic liver failure. Hepatobiliary Pancreat Dis Int. 2023 Oct; 22(5):474-481. Hartmann P, Lang S, Schierwagen R, Klein S, Praktiknjo M, Trebicka J, Schnabl B. PMID: 37198098; PMCID: PMC10797562.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. Serum keratin 18-M65 levels detect progressive forms of alcohol-associated liver disease in early noncirrhotic stages. Alcohol Clin Exp Res (Hoboken). 2023 Jun; 47(6):1079-1087. Maccioni L, Horsmans Y, Leclercq I, Schnabl B, Stärkel P. PMID: 37060262; PMCID: PMC10803128.
      View in: PubMed   Mentions:
    52. Toll-like receptor 2 activation in monocytes contributes to systemic inflammation and alcohol-associated liver disease in humans. Hepatol Commun. 2023 05 01; 7(5). Maccioni L, Kasavuli J, Leclercq S, Pirlot B, Laloux G, Horsmans Y, Leclercq I, Schnabl B, Stärkel P. PMID: 37058088; PMCID: PMC10109139.
      View in: PubMed   Mentions:
    53. Global and national prevalence of nonalcoholic fatty liver disease in adolescents: An analysis of the global burden of disease study 2019. Hepatology. 2023 10 01; 78(4):1168-1181. Hartmann P, Zhang X, Loomba R, Schnabl B. PMID: 37021791; PMCID: PMC10521800.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    54. Engineered bacteria producing aryl-hydrocarbon receptor agonists protect against ethanol-induced liver disease in mice. Alcohol Clin Exp Res (Hoboken). 2023 May; 47(5):856-867. Kouno T, Zeng S, Wang Y, Duan Y, Lang S, Gao B, Hartmann P, Cabré N, Llorente C, Galbert C, Emond P, Sokol H, James M, Chao CC, Gao JR, Perreault M, Hava DL, Schnabl B. PMID: 36871955; PMCID: PMC10795770.
      View in: PubMed   Mentions: 16     Fields:    
    55. Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease. Cell Host Microbe. 2023 03 08; 31(3):389-404.e7. Zeng S, Rosati E, Saggau C, Messner B, Chu H, Duan Y, Hartmann P, Wang Y, Ma S, Huang WJM, Lee J, Lee SM, Carvalho-Gontijo R, Zhang V, Hoffmann JP, Kolls JK, Raz E, Brenner DA, Kisseleva T, LeibundGut-Landmann S, Bacher P, Stärkel P, Schnabl B. PMID: 36893735; PMCID: PMC10039706.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    56. IgY antibodies against cytolysin reduce ethanol-induced liver disease in mice. Hepatology. 2023 07 01; 78(1):295-306. Cabré N, Hartmann P, Llorente C, Kouno T, Wang Y, Zeng S, Kim HY, Zhang X, Kisseleva T, Iyer S, Kudumala S, Schnabl B. PMID: 36811393; PMCID: PMC10293100.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    57. Differences in Bacterial Translocation and Liver Injury in Ethanol Versus Diet-Induced Liver Disease. Dig Dis Sci. 2023 07; 68(7):3059-3069. Hsu CL, Wang Y, Duan Y, Chu H, Hartmann P, Llorente C, Zhou R, Schnabl B. PMID: 36807831; PMCID: PMC10313731.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    58. Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice. bioRxiv. 2023 Feb 04. Borin JM, Liu R, Wang Y, Wu TC, Chopyk J, Huang L, Kuo P, Ghose C, Meyer JR, Tu XM, Schnabl B, Pride DT. PMID: 36778328; PMCID: PMC9915734.
      View in: PubMed   Mentions:
    59. Malassezia restricta promotes alcohol-induced liver injury. Hepatol Commun. 2023 02 01; 7(2):e0029. Zeng S, Hartmann P, Park M, Duan Y, Lang S, Llorente C, Wang Y, Cabré N, Fouts DE, Bacher P, Jung WH, Stärkel P, Schnabl B. PMID: 36706195; PMCID: PMC9988279.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    60. Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice. Gut. 2023 10; 72(10):1959-1970. Hendrikx T, Lang S, Rajcic D, Wang Y, McArdle S, Kim K, Mikulski Z, Schnabl B. PMID: 36690432; PMCID: PMC10841342.
      View in: PubMed   Mentions:
    61. Any alcohol use in NAFLD patients is associated with significant changes to the intestinal virome. Hepatology. 2023 06 01; 77(6):2073-2083. Hsu CL, Lang S, Demir M, Fouts DE, Stärkel P, Schnabl B. PMID: 36631002; PMCID: PMC10192041.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    62. Can a mucosal microbiota signature predict disease severity, survival, and disease recurrence in PSC? Hepatology. 2023 03 01; 77(3):709-711. Hartmann P, Schnabl B. PMID: 36626635.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    63. Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice. Gut Microbes. 2023 Jan-Dec; 15(1):2236750. Borin JM, Liu R, Wang Y, Wu TC, Chopyk J, Huang L, Kuo P, Ghose C, Meyer JR, Tu XM, Schnabl B, Pride DT. PMID: 37475473; PMCID: PMC10364654.
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    64. Fungal infections and the fungal microbiome in hepatobiliary disorders. J Hepatol. 2023 04; 78(4):836-851. Hartmann P, Schnabl B. PMID: 36565724; PMCID: PMC10033447.
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    65. Correlation between Serum Steroid Hormones and Gut Microbiota in Patients with Alcohol-Associated Liver Disease. Metabolites. 2022 Nov 13; 12(11). Gao B, Zhu Y, Shen W, Stärkel P, Schnabl B. PMID: 36422247; PMCID: PMC9699110.
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    66. Sarcopenia-related gut microbial changes are associated with the risk of complications in people with cirrhosis. JHEP Rep. 2023 Jan; 5(1):100619. Lee PC, Lee KC, Yang TC, Lu HS, Cheng TY, Chen YJ, Chiou JJ, Huang CW, Yang UC, Chia-Hui Tan E, Chou SH, Kuo YL, Schnabl B, Huang YH, Hou MC. PMID: 36536957; PMCID: PMC9758430.
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    67. Inexpensive, Accurate, and Stable Method to Quantitate Blood Alanine Aminotransferase (ALT) Levels. Methods Protoc. 2022 Oct 14; 5(5). Hartmann P, Schnabl B. PMID: 36287053; PMCID: PMC9610295.
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    68. Liver cirrhosis and immune dysfunction. Int Immunol. 2022 09 06; 34(9):455-466. Hasa E, Hartmann P, Schnabl B. PMID: 35792761; PMCID: PMC9447994.
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    69. Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Semin Liver Dis. 2022 08; 42(3):233-249. Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. PMID: 36001995; PMCID: PMC9662188.
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    70. Acetate reprograms gut microbiota during alcohol consumption. Nat Commun. 2022 08 08; 13(1):4630. Martino C, Zaramela LS, Gao B, Embree M, Tarasova J, Parker SJ, Wang Y, Chu H, Chen P, Lee KC, Galzerani DD, Gengatharan JM, Lekbua A, Neal M, Knight R, Tsukamoto H, Metallo CM, Schnabl B, Zengler K. PMID: 35941112; PMCID: PMC9359997.
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    71. Duodenal CD8+ T resident memory cell apoptosis contributes to gut barrier dysfunction and microbial translocation in early alcohol-associated liver disease in humans. Aliment Pharmacol Ther. 2022 09; 56(6):1055-1070. Maccioni L, Loriot A, Dewulf J, Bommer G, Horsmans Y, Lanthier N, Leclercq I, Schnabl B, Stärkel P. PMID: 35919965; PMCID: PMC9398988.
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    73. Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway. J Biol Chem. 2022 07; 298(7):102056. Kouno T, Liu X, Zhao H, Kisseleva T, Cable EE, Schnabl B. PMID: 35605662; PMCID: PMC9214809.
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    74. Lipidomics for the Prediction of Progressive Liver Disease in Patients with Alcohol Use Disorder. Metabolites. 2022 May 11; 12(5). Gao B, Zeng S, Maccioni L, Shi X, Armando A, Quehenberger O, Zhang X, Stärkel P, Schnabl B. PMID: 35629937; PMCID: PMC9146183.
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    76. RORγt phosphorylation protects against T cell-mediated inflammation. Cell Rep. 2022 03 15; 38(11):110520. Ma S, Patel SA, Abe Y, Chen N, Patel PR, Cho BS, Abbasi N, Zeng S, Schnabl B, Chang JT, Huang WJM. PMID: 35294872; PMCID: PMC8982147.
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    77. Effect of rifaximin on infections, acute-on-chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA-AH). Liver Int. 2022 05; 42(5):1109-1120. Jiménez C, Ventura-Cots M, Sala M, Calafat M, Garcia-Retortillo M, Cirera I, Cañete N, Soriano G, Poca M, Simón-Talero M, Altamirano J, Lucey M, Garcia-Tsao G, Brown RS, Schwabe RF, Verna EC, Schnabl B, Bosques-Padilla F, Mathurin P, Caballería J, Louvet A, Shawcross DL, Abraldes JG, Genescà J, Bataller R, Vargas V. PMID: 35220659; PMCID: PMC9311407.
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    80. Role of the Gut Microbiota in Parenteral Nutrition-Associated Liver Disease: From Current Knowledge to Future Opportunities. J Nutr. 2022 02 08; 152(2):377-385. Jiang L, Wang Y, Xiao Y, Wang Y, Yan J, Schnabl B, Cai W. PMID: 34734271.
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    81. Systemic Activin Is Elevated in Patients With Severe Alcoholic Hepatitis. Gastro Hep Adv. 2022; 1(2):147-149. Staudacher JJ, Bauer J, Atkinson SR, Thursz M, Lang S, Schnabl B, Wiley MB, Carr R, Jung B. PMID: 35602917; PMCID: PMC9119346.
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    83. Liver specific, systemic and genetic contributors to alcohol-related liver disease progression. Z Gastroenterol. 2022 Jan; 60(1):36-44. Schnabl B, Arteel GE, Stickel F, Hengstler J, Vartak N, Ghallab A, Dooley S, Li Y, Schwabe RF. PMID: 35042252; PMCID: PMC8941985.
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    88. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease. Nat Commun. 2021 12 09; 12(1):7172. Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, Hosseini M, Kisseleva T, Brenner DA, Bataller R, Ramachandran P, Karin M, Fu W, Schnabl B. PMID: 34887405; PMCID: PMC8660815.
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    89. Host Factors in Dysregulation of the Gut Barrier Function during Alcohol-Associated Liver Disease. Int J Mol Sci. 2021 Nov 24; 22(23). Maccioni L, Leclercq IA, Schnabl B, Stärkel P. PMID: 34884492; PMCID: PMC8657823.
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    91. Integrative Analysis of Metabolome and Microbiome in Patients with Progressive Alcohol-Associated Liver Disease. Metabolites. 2021 Nov 10; 11(11). Gao B, Zhu Y, Gao N, Shen W, Stärkel P, Schnabl B. PMID: 34822424; PMCID: PMC8621614.
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    95. Update on the Role of the Gut Microbiota on Alcohol-Associated Liver Disease. Gastroenterol Hepatol (N Y). 2021 Aug; 17(8):381-383. Schnabl B. PMID: 34602901; PMCID: PMC8475262.
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    98. The microbiota in cirrhosis and its role in hepatic decompensation. J Hepatol. 2021 07; 75 Suppl 1:S67-S81. Trebicka J, Macnaughtan J, Schnabl B, Shawcross DL, Bajaj JS. PMID: 34039493; PMCID: PMC8973011.
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    101. (Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-β1/SMAD3 Pathway. Cell Mol Gastroenterol Hepatol. 2021; 12(3):813-838. Hsieh YC, Lee KC, Lei HJ, Lan KH, Huo TI, Lin YT, Chan CC, Schnabl B, Huang YH, Hou MC, Lin HC. PMID: 34087453; PMCID: PMC8340309.
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    103. Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease. Liver Int. 2021 07; 41(7):1576-1591. Lang S, Martin A, Zhang X, Farowski F, Wisplinghoff H, J G T Vehreschild M, Krawczyk M, Nowag A, Kretzschmar A, Scholz C, Kasper P, Roderburg C, Mohr R, Lammert F, Tacke F, Schnabl B, Goeser T, Steffen HM, Demir M. PMID: 33896117; PMCID: PMC8947846.
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    106. Fungi-Bacteria Correlation in Alcoholic Hepatitis Patients. Toxins (Basel). 2021 02 14; 13(2). Gao B, Zhang X, Schnabl B. PMID: 33672887; PMCID: PMC7917833.
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    112. Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes. Sci Rep. 2020 12 10; 10(1):21732. Wang Z, Wang Y, Bradbury N, Gonzales Bravo C, Schnabl B, Di Nardo A. PMID: 33303806; PMCID: PMC7728784.
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    115. Persistent SARS-CoV-2 RNA Positive in Feces but Negative in Breastmilk: A Case Report of COVID-19 in a Breastfeeding Patient. Front Med (Lausanne). 2020; 7:562700. Chu H, Li J, Yan J, Bai T, Schnabl B, Zou L, Yang L, Hou X. PMID: 33344466; PMCID: PMC7738631.
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    185. Lamin Deficiency in the Liver Sets the Stage for Nonalcoholic Steatohepatitis Development in Males. Cell Mol Gastroenterol Hepatol. 2017 Nov; 4(3):441-442. Hendrikx T, Schnabl B. PMID: 29062878; PMCID: PMC5650600.
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    186. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017 Jun 30; 127(7):2829-2841. Yang AM, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, Bluemel S, Hartmann P, Xu J, Koyama Y, Kisseleva T, Torralba MG, Moncera K, Beeri K, Chen CS, Freese K, Hellerbrand C, Lee SM, Hoffman HM, Mehal WZ, Garcia-Tsao G, Mutlu EA, Keshavarzian A, Brown GD, Ho SB, Bataller R, Stärkel P, Fouts DE, Schnabl B. PMID: 28530644; PMCID: PMC5490775.
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    187. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5. Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. PMID: 28467925; PMCID: PMC5502730.
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    188. Intestinal microbiota and nonalcoholic steatohepatitis. Curr Opin Gastroenterol. 2017 May; 33(3):128-133. Brandl K, Schnabl B. PMID: 28257306; PMCID: PMC5662009.
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    189. Bidirectional Communication between Liver and Gut during Alcoholic Liver Disease. Semin Liver Dis. 2016 09; 36(4):331-339. Stärkel P, Schnabl B. PMID: 27997973.
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    190. Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. Hepatology. 2017 02; 65(2):475-490. Eguchi A, Lazaro RG, Wang J, Kim J, Povero D, Willliams B, Ho SB, Stärkel P, Schnabl B, Ohno-Machado L, Tsukamoto H, Feldstein AE. PMID: 27639178; PMCID: PMC5407075.
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    191. Genetic Loss of Immunoglobulin A Does Not Influence Development of Alcoholic Steatohepatitis in Mice. Alcohol Clin Exp Res. 2016 12; 40(12):2604-2613. Inamine T, Yang AM, Wang L, Lee KC, Llorente C, Schnabl B. PMID: 27739086; PMCID: PMC5133156.
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    192. Weight Loss Decreases Magnetic Resonance Elastography Estimated Liver Stiffness in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2017 03; 15(3):463-464. Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner D, Sirlin CB, Loomba R. PMID: 27712981; PMCID: PMC5476292.
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    193. Precision medicine in alcoholic and nonalcoholic fatty liver disease via modulating the gut microbiota. Am J Physiol Gastrointest Liver Physiol. 2016 12 01; 311(6):G1018-G1036. Bluemel S, Williams B, Knight R, Schnabl B. PMID: 27686615; PMCID: PMC5206291.
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    194. Fast-Track Clearance of Bacteria from the Liver. Cell Host Microbe. 2016 07 13; 20(1):1-2. Llorente C, Schnabl B. PMID: 27414492.
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    195. Microbiota and Alcoholic Liver Disease. Alcohol Clin Exp Res. 2016 08; 40(8):1791-2. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 27364225.
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    196. Acute-on-chronic liver failure in cirrhosis. Nat Rev Dis Primers. 2016 06 09; 2:16041. Arroyo V, Moreau R, Kamath PS, Jalan R, Ginès P, Nevens F, Fernández J, To U, García-Tsao G, Schnabl B. PMID: 27277335.
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    197. Editors' Introduction to the NAFLD and NASH Special Issue. Dig Dis Sci. 2016 May; 61(5):1211-3. Fuchs M, Schnabl B. PMID: 27068170.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    198. Liver capsule: Mechanisms of alcoholic hepatitis. Hepatology. 2016 07; 64(1):276. Schnabl B. PMID: 26867027.
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    199. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cell Host Microbe. 2016 Feb 10; 19(2):227-39. Wang L, Fouts DE, Stärkel P, Hartmann P, Chen P, Llorente C, DePew J, Moncera K, Ho SB, Brenner DA, Hooper LV, Schnabl B. PMID: 26867181; PMCID: PMC4786170.
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    200. Does the Intestinal Microbiota Explain Differences in the Epidemiology of Liver Disease between East and West? Inflamm Intest Dis. 2016 Apr; 1(1):3-8. Nakamoto N, Schnabl B. PMID: 27243019; PMCID: PMC4883108.
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    201. Changes in Hospital Admissions and Mortality for Complications of Cirrhosis: Implications for Clinicians and Health Systems. Gut Liver. 2016 Jan; 10(1):8-9. Ho SB, Matheny ME, Schnabl BE. PMID: 26696026; PMCID: PMC4694728.
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    202. Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 01; 310(5):G310-22. Hartmann P, Seebauer CT, Mazagova M, Horvath A, Wang L, Llorente C, Varki NM, Brandl K, Ho SB, Schnabl B. PMID: 26702135; PMCID: PMC4773827.
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    203. Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. Nucl Med Biol. 2016 Feb; 43(2):179-87. Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. PMID: 26872443.
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    204. Microbiota Protects Mice Against Acute Alcohol-Induced Liver Injury. Alcohol Clin Exp Res. 2015 Dec; 39(12):2313-23. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 26556636; PMCID: PMC4712135.
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    205. Role of Gut Microbiota in Liver Disease. J Clin Gastroenterol. 2015 Nov-Dec; 49 Suppl 1:S25-7. Brenner DA, Paik YH, Schnabl B. PMID: 26447960; PMCID: PMC4602394.
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    206. Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis. J Hepatol. 2015 Nov; 63(5):1272-84. Bernardi M, Moreau R, Angeli P, Schnabl B, Arroyo V. PMID: 26192220.
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    207. Is intestinal inflammation linking dysbiosis to gut barrier dysfunction during liver disease? Expert Rev Gastroenterol Hepatol. 2015; 9(8):1069-76. Brandl K, Schnabl B. PMID: 26088524; PMCID: PMC4828034.
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    208. Alcoholic liver disease: the gut microbiome and liver cross talk. Alcohol Clin Exp Res. 2015 May; 39(5):763-75. Hartmann P, Seebauer CT, Schnabl B. PMID: 25872593; PMCID: PMC4402724.
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    209. The gut microbiota and liver disease. Cell Mol Gastroenterol Hepatol. 2015 May 01; 1(3):275-284. Llorente C, Schnabl B. PMID: 26090511; PMCID: PMC4467911.
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    210. Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2015 Aug; 13(8):1513-20.e1. Arulanandan A, Ang B, Bettencourt R, Hooker J, Behling C, Lin GY, Valasek MA, Ix JH, Schnabl B, Sirlin CB, Loomba R. PMID: 25661453.
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    211. Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice. Hepatology. 2015 Mar; 61(3):883-94. Chen P, Stärkel P, Turner JR, Ho SB, Schnabl B. PMID: 25251280; PMCID: PMC4340725.
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    212. Methods to determine intestinal permeability and bacterial translocation during liver disease. J Immunol Methods. 2015 Jun; 421:44-53. Wang L, Llorente C, Hartmann P, Yang AM, Chen P, Schnabl B. PMID: 25595554; PMCID: PMC4451427.
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    213. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med. 2015 Feb; 21(2):159-65. Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. PMID: 25559344; PMCID: PMC4320010.
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    214. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB J. 2015 Mar; 29(3):1043-55. Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. PMID: 25466902; PMCID: PMC4422368.
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    215. Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. Gastroenterology. 2015 Jan; 148(1):203-214.e16. Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, van Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B. PMID: 25239591; PMCID: PMC4274236.
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    216. Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2015 Mar; 13(3):561-568.e1. Patel NS, Doycheva I, Peterson MR, Hooker J, Kisselva T, Schnabl B, Seki E, Sirlin CB, Loomba R. PMID: 25218667; PMCID: PMC4333065.
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    217. The Microbiome and the Liver. Gastroenterol Hepatol (N Y). 2014 Aug; 10(8):519-521. Schnabl B. PMID: 28845144; PMCID: PMC5566188.
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    218. Host-microbiome interactions in alcoholic liver disease. Gut Liver. 2014 May; 8(3):237-41. Chen P, Schnabl B. PMID: 24827618; PMCID: PMC4026639.
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    219. Transplanting a fibrogenic microbiota. Hepatology. 2014 May; 59(5):1660-1. Schnabl B. PMID: 24676698.
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    220. Nod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids. J Hepatol. 2014 Jun; 60(6):1259-67. Wang L, Hartmann P, Haimerl M, Bathena SP, Sjöwall C, Almer S, Alnouti Y, Hofmann AF, Schnabl B. PMID: 24560660; PMCID: PMC4028388.
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    221. Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013. J Hepatol. 2014 Jun; 60(6):1310-24. Jalan R, Fernandez J, Wiest R, Schnabl B, Moreau R, Angeli P, Stadlbauer V, Gustot T, Bernardi M, Canton R, Albillos A, Lammert F, Wilmer A, Mookerjee R, Vila J, Garcia-Martinez R, Wendon J, Such J, Cordoba J, Sanyal A, Garcia-Tsao G, Arroyo V, Burroughs A, Ginès P. PMID: 24530646.
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    222. Interactions between the intestinal microbiome and liver diseases. Gastroenterology. 2014 May; 146(6):1513-24. Schnabl B, Brenner DA. PMID: 24440671; PMCID: PMC3996054.
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    223. Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls. Gastroenterol Res Pract. 2013; 2013:498296. Patel NS, Peterson MR, Lin GY, Feldstein A, Schnabl B, Bettencourt R, Seki E, Sirlin CB, Loomba R. PMID: 24348536; PMCID: PMC3855930.
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    224. Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice. Hepatology. 2013 Jul; 58(1):108-19. Hartmann P, Chen P, Wang HJ, Wang L, McCole DF, Brandl K, Stärkel P, Belzer C, Hellerbrand C, Tsukamoto H, Ho SB, Schnabl B. PMID: 23408358; PMCID: PMC3695050.
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    225. Linking intestinal homeostasis and liver disease. Curr Opin Gastroenterol. 2013 May; 29(3):264-70. Schnabl B. PMID: 23493073; PMCID: PMC4077188.
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    226. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 2012 Nov 08; 491(7423):254-8. Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, Taniguchi K, Yu GY, Osterreicher CH, Hung KE, Datz C, Feng Y, Fearon ER, Oukka M, Tessarollo L, Coppola V, Yarovinsky F, Cheroutre H, Eckmann L, Trinchieri G, Karin M. PMID: 23034650; PMCID: PMC3601659.
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    227. The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease. Front Physiol. 2012; 3:402. Hartmann P, Chen WC, Schnabl B. PMID: 23087650; PMCID: PMC3468817.
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    228. Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice. Gastroenterology. 2012 Nov; 143(5):1330-1340.e1. Hartmann P, Haimerl M, Mazagova M, Brenner DA, Schnabl B. PMID: 22841787; PMCID: PMC3482543.
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    229. Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12650-5. Brandl K, Tomisato W, Li X, Neppl C, Pirie E, Falk W, Xia Y, Moresco EM, Baccala R, Theofilopoulos AN, Schnabl B, Beutler B. PMID: 22802641; PMCID: PMC3412000.
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    230. Fibroblast growth factor inducible 14 as potential target in patients with alcoholic hepatitis. Gut. 2013 Mar; 62(3):335-6. Schnabl B, Brenner DA. PMID: 22717452; PMCID: PMC4077319.
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    231. Origin of myofibroblasts in liver fibrosis. Fibrogenesis Tissue Repair. 2012; 5(Suppl 1):S17. Brenner DA, Kisseleva T, Scholten D, Paik YH, Iwaisako K, Inokuchi S, Schnabl B, Seki E, De Minicis S, Oesterreicher C, Taura K. PMID: 23259769; PMCID: PMC3368775.
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    232. Bacterial translocation and changes in the intestinal microbiome associated with alcoholic liver disease. World J Hepatol. 2012 Apr 27; 4(4):110-8. Yan AW, Schnabl B. PMID: 22567183; PMCID: PMC3345535.
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    233. Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):E1369-76. Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. PMID: 22538808; PMCID: PMC3361396.
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    234. Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease. J Hepatol. 2012 Jun; 56(6):1283-92. Fouts DE, Torralba M, Nelson KE, Brenner DA, Schnabl B. PMID: 22326468; PMCID: PMC3357486.
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    235. Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut. J Physiol. 2012 Feb 01; 590(3):447-58. Seki E, Schnabl B. PMID: 22124143; PMCID: PMC3379693.
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    236. Increased expression of zinc finger protein 267 in non-alcoholic fatty liver disease. Int J Clin Exp Pathol. 2011; 4(7):661-6. Schnabl B, Czech B, Valletta D, Weiss TS, Kirovski G, Hellerbrand C. PMID: 22076166; PMCID: PMC3209606.
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    237. Zinc finger protein 267 is up-regulated in hepatocellular carcinoma and promotes tumor cell proliferation and migration. Exp Mol Pathol. 2011 Dec; 91(3):695-701. Schnabl B, Valletta D, Kirovski G, Hellerbrand C. PMID: 21840307; PMCID: PMC3342774.
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    238. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. Hepatol Res. 2011 Jul; 41(7):683-6. Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. PMID: 21711427; PMCID: PMC3341613.
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    239. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology. 2011 May; 53(5):1730-41. Paik YH, Iwaisako K, Seki E, Inokuchi S, Schnabl B, Osterreicher CH, Kisseleva T, Brenner DA. PMID: 21384410; PMCID: PMC3082608.
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    240. X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7890-5. Siggs OM, Schnabl B, Webb B, Beutler B. PMID: 21518881; PMCID: PMC3093471.
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    241. CXCL5 plasma levels decrease in patients with chronic liver disease. J Gastroenterol Hepatol. 2011 Mar; 26(3):523-9. Tacke F, Zimmermann HW, Trautwein C, Schnabl B. PMID: 21332547; PMCID: PMC3058722.
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    242. Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Hepatology. 2011 Jan; 53(1):96-105. Yan AW, Fouts DE, Brandl J, Stärkel P, Torralba M, Schott E, Tsukamoto H, Nelson KE, Brenner DA, Schnabl B. PMID: 21254165; PMCID: PMC3059122.
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    243. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 2010 Jul; 139(1):323-34.e7. Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. PMID: 20347818; PMCID: PMC4631262.
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    244. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5. Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA. PMID: 19549522; PMCID: PMC2757473.
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    245. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3300-5. Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B. PMID: 19202076; PMCID: PMC2651297.
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    246. Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis. Gastroenterology. 2009 Apr; 136(4):1423-34. Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA. PMID: 19249395.
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    247. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology. 2008 Dec; 48(6):2016-26. De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA. PMID: 19025999.
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    248. Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Hepatology. 2008 Nov; 48(5):1420-9. Miura K, Taura K, Kodama Y, Schnabl B, Brenner DA. PMID: 18671304.
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    249. Role of TLR9 in hepatic stellate cells and experimental liver fibrosis. Biochem Biophys Res Commun. 2008 Nov 14; 376(2):271-6. Gäbele E, Mühlbauer M, Dorn C, Weiss TS, Froh M, Schnabl B, Wiest R, Schölmerich J, Obermeier F, Hellerbrand C. PMID: 18760996.
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    250. Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits. Nature. 2008 Oct 09; 455(7214):804-7. Brandl K, Plitas G, Mihu CN, Ubeda C, Jia T, Fleisher M, Schnabl B, DeMatteo RP, Pamer EG. PMID: 18724361; PMCID: PMC2663337.
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    251. A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells. Biochem Biophys Res Commun. 2008 Oct 17; 375(2):210-4. Schnabl B, Brandl K, Fink M, Gross P, Taura K, Gäbele E, Hellerbrand C, Falk W. PMID: 18694726.
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    252. What is the potential role of antifibrotic agents for the treatment of liver disease? Nat Clin Pract Gastroenterol Hepatol. 2008 Sep; 5(9):496-7. Schnabl B, Scholten D, Brenner DA. PMID: 18628735.
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    253. Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course. J Gastroenterol Hepatol. 2007 Aug; 22(8):1256-64. Tacke F, Trautwein C, Yagmur E, Hellerbrand C, Wiest R, Brenner DA, Schnabl B. PMID: 17688666.
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    254. MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection. J Exp Med. 2007 Aug 06; 204(8):1891-900. Brandl K, Plitas G, Schnabl B, DeMatteo RP, Pamer EG. PMID: 17635956; PMCID: PMC2118673.
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    255. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Dig Dis Sci. 2007 Dec; 52(12):3404-15. Tacke F, Gäbele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Schölmerich J, Schnabl B. PMID: 17415633.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    256. Different effects of a CD14 gene polymorphism on disease outcome in patients with alcoholic liver disease and chronic hepatitis C infection. World J Gastroenterol. 2005 Oct 14; 11(38):6031-7. Meiler C, Muhlbauer M, Johann M, Hartmann A, Schnabl B, Wodarz N, Schmitz G, Scholmerich J, Hellerbrand C. PMID: 16273620; PMCID: PMC4436730.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    257. Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension. J Hepatol. 2006 Mar; 44(3):512-9. Wiest R, Jurzik L, Moleda L, Froh M, Schnabl B, von Hörsten S, Schölmerich J, Straub RH. PMID: 16324766.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    258. Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10. Biochem Biophys Res Commun. 2005 Sep 16; 335(1):87-96. Schnabl B, Hu K, Mühlbauer M, Hellerbrand C, Stefanovic B, Brenner DA, Schölmerich J. PMID: 16054593.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    259. Characterization of the human zinc finger protein 267 promoter: essential role of nuclear factor Y. Biochim Biophys Acta. 2005 May 25; 1729(1):14-23. Hu K, Fink M, Froh M, Gäbele E, Hellerbrand C, Mühlbauer M, Wiest R, Schölmerich J, Schnabl B. PMID: 15814297.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    260. DNA microarrays and data mining to study hepatic fibrosis. Methods Mol Med. 2005; 117:359-69. Schnabl B, Choi YH, Hagedorn CH, Bataller R. PMID: 16118462.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    261. LPS-mediated NFkappaB activation varies between activated human hepatic stellate cells from different donors. Biochem Biophys Res Commun. 2004 Dec 03; 325(1):191-7. Mühlbauer M, Weiss TS, Thasler WE, Gelbmann CM, Schnabl B, Schölmerich J, Hellerbrand C. PMID: 15522218.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    262. TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Mol Cell Biol. 2004 Feb; 24(4):1758-68. Stefanovic B, Stefanovic L, Schnabl B, Bataller R, Brenner DA. PMID: 14749390; PMCID: PMC344171.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    263. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. J Hepatol. 2003 Jul; 39(1):38-46. Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ, Brenner DA. PMID: 12821042.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    264. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology. 2003 Mar; 37(3):653-64. Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D. PMID: 12601363.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    265. Inhibition of collagen alpha 1(I) expression by the 5' stem-loop as a molecular decoy. J Biol Chem. 2002 May 17; 277(20):18229-37. Stefanovic B, Schnabl B, Brenner DA. PMID: 11889120.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    266. Immortal activated human hepatic stellate cells generated by ectopic telomerase expression. Lab Invest. 2002 Mar; 82(3):323-33. Schnabl B, Choi YH, Olsen JC, Hagedorn CH, Brenner DA. PMID: 11896211.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    267. TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells. Hepatology. 2001 Nov; 34(5):953-63. Schnabl B, Bradham CA, Bennett BL, Manning AM, Stefanovic B, Brenner DA. PMID: 11679966.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    268. The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology. 2001 Jul; 34(1):89-100. Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA. PMID: 11431738.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    269. CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J Immunol. 2001 Jun 01; 166(11):6812-9. Schwabe RF, Schnabl B, Kweon YO, Brenner DA. PMID: 11359840.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
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