Alan Saltiel

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-9726-9828 Additional info
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    Hormonal regulation of LDL receptor trafficking
    NIH R01DK128796Sep 20, 2021 - Jul 31, 2025
    Role: Principal Investigator
    Regulating energy expenditure in adipose tissue
    NIH R01DK124496Sep 11, 2020 - Jun 30, 2025
    Role: Principal Investigator
    Inflammation and hepatic lipid metabolism
    NIH/NIDDK R01DK125820Jul 1, 2020 - Jun 30, 2024
    Role: Principal Investigator
    Adipose tissue plasticity in health and disease
    NIH/NIDDK R01DK122804Jul 1, 2020 - Apr 30, 2024
    Role: Principal Investigator
    Regulation of glycogen in health and disease
    NIH/NIDDK R01DK117551Jul 1, 2018 - May 31, 2022
    Role: Principal Investigator
    IKKepsilon/TBK1 Inhibitors for the Treatment of Obesity and Type 2 Diabetes
    NIH/NIDDK R01DK100319Jan 1, 2014 - Dec 31, 2017
    Role: Principal Investigator
    Probing the relevance of the "counter-inflammatory" noncanonical IkB kinases in r
    NIH/NIDDK R21DK098776Sep 18, 2013 - Jul 31, 2015
    Role: Principal Investigator
    The Role of G Proteins in Insulin Action
    NIH/NIDDK R01DK061618Jan 15, 2010 - Mar 31, 2010
    Role: Principal Investigator
    The Role of the Exocyst Complex in Insulin Regulated Glucose Transport
    NIH/NIDDK R01DK076906Aug 1, 2007 - May 31, 2020
    Role: Principal Investigator
    Diabetes Research Center (DRC)
    NIH P30DK063491Dec 1, 2002 - Jun 30, 2025
    Role: Principal Investigator
    Hormonal Regulation of Glycogen Synthesis
    NIH/NIDDK R01DK060597Feb 15, 2002 - Mar 31, 2007
    Role: Principal Investigator
    Signaling Pathways in Insulin Action
    NIH/NIDDK R01DK060591Feb 1, 2002 - Mar 31, 2013
    Role: Principal Investigator
    DETERMINANTS OF SPECIFICITY IN SIGNAL TRANSDUCTION
    NIH/NIDDK R13DK053164Apr 1, 1997 - Mar 31, 1998
    Role: Principal Investigator
    Training Program in Diabetes Research
    NIH T32DK007494Jul 1, 1984 - Aug 31, 2022
    Role: Co-Principal Investigator
    MOLECULAR MECHANISMS OF INSULIN ACTION
    NIH/NIDDK R01DK033804Jul 1, 1984 - Jun 30, 1992
    Role: Principal Investigator
    MOLECULAR MECHANISMS OF INSULIN ACTION
    NIH/NIADDK R23AM033804Jul 1, 1984 - Jun 30, 1987
    Role: Principal Investigator
    MOLECULAR MECHANISMS OF INSULIN ACTION
    NIH/NIDDK R23DK033804Jul 1, 1984 - Jun 30, 1987
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. β3-adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity. J Clin Invest. 2021 Nov 30. Valentine JM, Ahmadian M, Keinan O, Abu-Odeh M, Zhao P, Zhou X, Keller MP, Gao H, Yu RT, Liddle C, Downes M, Zhang J, Lusis AJ, Attie AD, Evans RM, Rydén M, Saltiel AR. PMID: 34847077.
      View in: PubMed   Mentions:
    2. Roles of I?B kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease. Exp Mol Med. 2021 Nov; 53(11):1697-1705. Huh JY, Saltiel AR. PMID: 34848839; PMCID: PMC8639992.
      View in: PubMed   Mentions:
    3. p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes. JCI Insight. 2021 Nov 23. Martins VF, LaBarge SA, Stanley A, Svensson K, Hung CW, Keinan O, Ciaraldi TP, Banoian D, Park JE, Ha C, Hetrick B, Meyer GA, Philp A, David LL, Henry RR, Aslan JE, Saltiel AR, McCurdy CE, Schenk S. PMID: 34813504.
      View in: PubMed   Mentions:
    4. Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. 2021 Oct 27. Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Lusis AJ, Laakso M, Chouchani ET, Ryde'n M, Saltiel AR. PMID: 34707293.
      View in: PubMed   Mentions:
    5. Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice. Sci Transl Med. 2021 07 28; 13(604). Yong J, Parekh VS, Reilly SM, Nayak J, Chen Z, Lebeaupin C, Jang I, Zhang J, Prakash TP, Sun H, Murray S, Guo S, Ayala JE, Satin LS, Saltiel AR, Kaufman RJ. PMID: 34321322.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. Cell Rep. 2021 Jun 29; 35(13):109331. Abu-Odeh M, Zhang Y, Reilly SM, Ebadat N, Keinan O, Valentine JM, Hafezi-Bakhtiari M, Ashayer H, Mamoun L, Zhou X, Zhang J, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Kliewer SA, Mangelsdorf DJ, Saltiel AR. PMID: 34192547; PMCID: PMC8293281.
      View in: PubMed   Mentions:    Fields:    
    7. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. J Clin Invest. 2021 05 17; 131(10). Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. PMID: 33822771; PMCID: PMC8121507.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPAR?. Nat Commun. 2021 05 17; 12(1):2876. Huang J, Linares JF, Duran A, Xia W, Saltiel AR, Müller TD, Diaz-Meco MT, Moscat J. PMID: 34001883; PMCID: PMC8129077.
      View in: PubMed   Mentions:
    9. Voices: Insulin and beyond. Cell Metab. 2021 04 06; 33(4):692-699. Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, Saltiel AR, Corkey BE, Atkinson MA. PMID: 33826910.
      View in: PubMed   Mentions:    Fields:    
    10. Insulin signaling in health and disease. J Clin Invest. 2021 01 04; 131(1). Saltiel AR. PMID: 33393497; PMCID: PMC7773347.
      View in: PubMed   Mentions:
    11. TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation. Cell Metab. 2020 12 01; 32(6):1012-1027.e7. Huh JY, Reilly SM, Abu-Odeh M, Murphy AN, Mahata SK, Zhang J, Cho Y, Seo JB, Hung CW, Green CR, Metallo CM, Saltiel AR. PMID: 33152322; PMCID: PMC7710607.
      View in: PubMed   Mentions: 2     Fields:    
    12. Interaction of Adipocyte Metabolic and Immune Functions Through TBK1. Front Immunol. 2020; 11:592949. Zhao P, Saltiel AR. PMID: 33193441; PMCID: PMC7606291.
      View in: PubMed   Mentions:
    13. From Overnutrition to Liver Injury: AMP-Activated Protein Kinase in Nonalcoholic Fatty Liver Diseases. J Biol Chem. 2020 07 10. Zhao P, Saltiel AR. PMID: 32651233.
      View in: PubMed   Mentions:    Fields:    
    14. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nat Metab. 2020 07; 2(7):620-634. Reilly SM, Hung CW, Ahmadian M, Zhao P, Keinan O, Gomez AV, DeLuca JH, Dadpey B, Lu D, Zaid J, Poirier B, Peng X, Yu RT, Downes M, Liddle C, Evans RM, Murphy AN, Saltiel AR. PMID: 32694788; PMCID: PMC7384260.
      View in: PubMed   Mentions: 6  Translation:AnimalsCells
    15. An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. Science. 2020 02 07; 367(6478):652-660. Zhao P, Sun X, Chaggan C, Liao Z, In Wong K, He F, Singh S, Loomba R, Karin M, Witztum JL, Saltiel AR. PMID: 32029622; PMCID: PMC8012106.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    16. Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities. Am J Hum Genet. 2020 02 06; 106(2):246-255. Wagner M, Skorobogatko Y, Pode-Shakked B, Powell CM, Alhaddad B, Seibt A, Barel O, Heimer G, Hoffmann C, Demmer LA, Perilla-Young Y, Remke M, Wieczorek D, Navaratnarajah T, Lichtner P, Klee D, Shamseldin HE, Al Mutairi F, Mayatepek E, Strom T, Meitinger T, Alkuraya FS, Anikster Y, Saltiel AR, Distelmaier F. PMID: 32004447; PMCID: PMC7010976.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metab. 2020 01 07; 31(1):189-206.e8. Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. PMID: 31761566; PMCID: PMC7028360.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    18. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):15184-15193. Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, Evans RM, Brenner DA, Saltiel AR, Beutler B, Schnabl B. PMID: 31289229; PMCID: PMC6660779.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    19. Hyaluronan as a potential thermogenic rheostat. Nat Metab. 2019 05; 1(5):503-504. Gordts PLSM, Saltiel AR. PMID: 32694849.
      View in: PubMed   Mentions:
    20. Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes. J Labelled Comp Radiopharm. 2019 05 15; 62(5):202-208. Gan X, Wilson MW, Beyett TS, Wen B, Sun D, Larsen SD, Tesmer JJG, Saltiel AR, Showalter HD. PMID: 30828860; PMCID: PMC6525014.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorg Med Chem. 2018 11 01; 26(20):5443-5461. Beyett TS, Gan X, Reilly SM, Gomez AV, Chang L, Tesmer JJG, Saltiel AR, Showalter HD. PMID: 30270002; PMCID: PMC6252132.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell. 2018 09 20; 175(1):133-145.e15. Kim JY, Garcia-Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, Kaufman RJ, Saltiel AR, Karin M. PMID: 30220454; PMCID: PMC6159928.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    23. Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition. Mol Pharmacol. 2018 10; 94(4):1210-1219. Beyett TS, Gan X, Reilly SM, Chang L, Gomez AV, Saltiel AR, Showalter HD, Tesmer JJG. PMID: 30082428; PMCID: PMC6128810.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7819-7824. Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, Saltiel AR. PMID: 29915037; PMCID: PMC6065037.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation. Hepatology. 2018 10; 68(4):1331-1346. Cho CS, Park HW, Ho A, Semple IA, Kim B, Jang I, Park H, Reilly S, Saltiel AR, Lee JH. PMID: 29251796; PMCID: PMC6005718.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    26. ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Rep. 2018 03 13; 22(11):2849-2859. Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, Saltiel AR, Downes M, Evans RM. PMID: 29539415; PMCID: PMC5884669.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    27. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 2018 02 08; 172(4):731-743.e12. Zhao P, Wong KI, Sun X, Reilly SM, Uhm M, Liao Z, Skorobogatko Y, Saltiel AR. PMID: 29425491; PMCID: PMC5808582.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    28. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. J Cell Sci. 2017 Oct 15; 130(20):3517-3531. Ichikawa T, Kita M, Matsui TS, Nagasato AI, Araki T, Chiang SH, Sezaki T, Kimura Y, Ueda K, Deguchi S, Saltiel AR, Kioka N. PMID: 28864765; PMCID: PMC5665443.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    29. Creatine Fuels the Thermic Effect of Feeding. Cell Metab. 2017 Oct 03; 26(4):594-595. Saltiel AR. PMID: 28844879.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    30. Adapting to obesity with adipose tissue inflammation. Nat Rev Endocrinol. 2017 Nov; 13(11):633-643. Reilly SM, Saltiel AR. PMID: 28799554.
      View in: PubMed   Mentions: 242     Fields:    Translation:HumansCells
    31. Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. Cell Metab. 2017 Jul 05; 26(1):157-170.e7. Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, Jain M, Yu R, Liddle C, Ahmadian M, Downes M, Evans RM, Saltiel AR. PMID: 28683283; PMCID: PMC5663294.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    32. Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking. Sci Signal. 2017 Mar 21; 10(471). Uhm M, Bazuine M, Zhao P, Chiang SH, Xiong T, Karunanithi S, Chang L, Saltiel AR. PMID: 28325821.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    33. Inflammatory mechanisms linking obesity and metabolic disease. J Clin Invest. 2017 01 03; 127(1):1-4. Saltiel AR, Olefsky JM. PMID: 28045402; PMCID: PMC5199709.
      View in: PubMed   Mentions: 340     Fields:    Translation:HumansAnimals
    34. New therapeutic approaches for the treatment of obesity. Sci Transl Med. 2016 Jan 27; 8(323):323rv2. Saltiel AR. PMID: 26819198.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    35. Insulin Signaling in the Control of Glucose and Lipid Homeostasis. Handb Exp Pharmacol. 2016; 233:51-71. Saltiel AR. PMID: 26721672.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    36. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Rep. 2016 Jan 12; 14(2):255-68. Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, Olefsky JM, Akassoglou K. PMID: 26748707; PMCID: PMC4831919.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    37. Metabolism: Inflammation keeps old mice healthy. Nature. 2015 Dec 03; 528(7580):44-6. Maillard I, Saltiel AR. PMID: 26580010.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    38. A futile approach to fighting obesity? Cell. 2015 Oct 22; 163(3):539-40. Reilly SM, Saltiel AR. PMID: 26496598.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    39. Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans. Mol Metab. 2016 Jan; 5(1):5-18. Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, Rodríguez MA, Yanes O, Núñez-Roa C, Roche K, Puthanveetil P, Garrido-Sánchez L, Saez E, Tinahones FJ, Garcia-Roves PM, Gómez-Foix AM, Saltiel AR, Vendrell J, Fernández-Veledo S. PMID: 26844203; PMCID: PMC4703799.
      View in: PubMed   Mentions: 8     Fields:    
    40. Gene expression changes in subcutaneous adipose tissue due to Cushing's disease. J Mol Endocrinol. 2015 Oct; 55(2):81-94. Hochberg I, Harvey I, Tran QT, Stephenson EJ, Barkan AL, Saltiel AR, Chandler WF, Bridges D. PMID: 26150553; PMCID: PMC4543687.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    41. Gene Expression Signature in Adipose Tissue of Acromegaly Patients. PLoS One. 2015; 10(6):e0129359. Hochberg I, Tran QT, Barkan AL, Saltiel AR, Chandler WF, Bridges D. PMID: 26087292; PMCID: PMC4472931.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    42. White, brown, and beige; type 2 immunity gets hot. Immunity. 2015 Jan 20; 42(1):15-7. Uhm M, Saltiel AR. PMID: 25607455.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    43. Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. J Biol Chem. 2015 Mar 06; 290(10):6376-86. Buchner DA, Charrier A, Srinivasan E, Wang L, Paulsen MT, Ljungman M, Bridges D, Saltiel AR. PMID: 25596527; PMCID: PMC4358273.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    44. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nat Commun. 2015 Jan 12; 6:6047. Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, Evans RM, Saltiel AR. PMID: 25581158; PMCID: PMC4324568.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    45. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med. 2015 Feb; 21(2):159-65. Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. PMID: 25559344; PMCID: PMC4320010.
      View in: PubMed   Mentions: 190     Fields:    Translation:Animals
    46. Phosphoinositides: Key modulators of energy metabolism. Biochim Biophys Acta. 2015 Jun; 1851(6):857-66. Bridges D, Saltiel AR. PMID: 25463477; PMCID: PMC4975561.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    47. A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. Mol Biol Cell. 2014 Oct 01; 25(19):3059-69. Karunanithi S, Xiong T, Uhm M, Leto D, Sun J, Chen XW, Saltiel AR. PMID: 25103239; PMCID: PMC4230594.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    48. The lipid kinase PI4KIIIß is highly expressed in breast tumors and activates Akt in cooperation with Rab11a. Mol Cancer Res. 2014 Oct; 12(10):1492-508. Morrow AA, Alipour MA, Bridges D, Yao Z, Saltiel AR, Lee JM. PMID: 24962317.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    49. Countering inflammatory signals in obesity. Nat Immunol. 2014 May; 15(5):410-1. Reilly SM, Saltiel AR. PMID: 24747704.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    50. SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling. PLoS One. 2014; 9(4):e95416. Liu S, Xu R, Gerin I, Cawthorn WP, Macdougald OA, Chen XW, Saltiel AR, Koenig RJ, Xu B. PMID: 24743795; PMCID: PMC3990642.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    51. Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. Diabetes. 2014 Sep; 63(9):2935-48. Lu B, Bridges D, Yang Y, Fisher K, Cheng A, Chang L, Meng ZX, Lin JD, Downes M, Yu RT, Liddle C, Evans RM, Saltiel AR. PMID: 24722244; PMCID: PMC4141363.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    52. Obesity: A complex role for adipose tissue macrophages. Nat Rev Endocrinol. 2014 Apr; 10(4):193-4. Reilly SM, Saltiel AR. PMID: 24492182.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    53. Roles for PI(3,5)P2 in nutrient sensing through TORC1. Mol Biol Cell. 2014 Apr; 25(7):1171-85. Jin N, Mao K, Jin Y, Tevzadze G, Kauffman EJ, Park S, Bridges D, Loewith R, Saltiel AR, Klionsky DJ, Weisman LS. PMID: 24478451; PMCID: PMC3967979.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    54. Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion. Mol Cell. 2014 Jan 23; 53(2):209-20. Martin TD, Chen XW, Kaplan RE, Saltiel AR, Walker CL, Reiner DJ, Der CJ. PMID: 24389102; PMCID: PMC3955741.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    55. Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. Diabetes. 2014 Apr; 63(4):1340-52. Wang GX, Cho KW, Uhm M, Hu CR, Li S, Cozacov Z, Xu AE, Cheng JX, Saltiel AR, Lumeng CN, Lin JD. PMID: 24379350; PMCID: PMC3964504.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    56. Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. Elife. 2013 Dec 24; 2:e01119. Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR. PMID: 24368730; PMCID: PMC3869376.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    57. Inhibition of AMPK catabolic action by GSK3. Mol Cell. 2013 May 09; 50(3):407-19. Suzuki T, Bridges D, Nakada D, Skiniotis G, Morrison SJ, Lin JD, Saltiel AR, Inoki K. PMID: 23623684; PMCID: PMC3654099.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    58. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar; 19(3):313-21. Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, Li P, Olefsky JM, Saltiel AR. PMID: 23396211; PMCID: PMC3594079.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
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    142. PPAR gamma and the treatment of insulin resistance. Trends Endocrinol Metab. 2000 Nov; 11(9):362-8. Olefsky JM, Saltiel AR. PMID: 11042466.
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    143. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 2000 Sep 14; 407(6801):202-7. Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR. PMID: 11001060.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    144. Series introduction: the molecular and physiological basis of insulin resistance: emerging implications for metabolic and cardiovascular diseases. J Clin Invest. 2000 Jul; 106(2):163-4. Saltiel AR. PMID: 10903328; PMCID: PMC314314.
      View in: PubMed   Mentions: 17     Fields:    
    145. Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest. 2000 Jul; 106(2):165-9. Pessin JE, Saltiel AR. PMID: 10903329; PMCID: PMC314316.
      View in: PubMed   Mentions: 155     Fields:    Translation:Cells
    146. Cloning and characterization of a functional peroxisome proliferator activator receptor-gamma-responsive element in the promoter of the CAP gene. J Biol Chem. 2000 Mar 31; 275(13):9131-5. Baumann CA, Chokshi N, Saltiel AR, Ribon V. PMID: 10734046.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    147. Another hormone-sensitive triglyceride lipase in fat cells? Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):535-7. Saltiel AR. PMID: 10639113; PMCID: PMC33961.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    148. Spatial Compartmentalization in the Regulation of Glucose Metabolism by Insulin. Trends Endocrinol Metab. 1999 Dec; 10(10):408-413. Brady MJ, Pessin JE, Saltiel AR. PMID: 10542398.
      View in: PubMed   Mentions:
    149. The role of glucose metabolites in the activation and translocation of glycogen synthase by insulin in 3T3-L1 adipocytes. J Biol Chem. 1999 Sep 24; 274(39):27497-504. Brady MJ, Kartha PM, Aysola AA, Saltiel AR. PMID: 10488084.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    150. Closing in on the cause of insulin resistance and type 2 diabetes. J Clin Invest. 1999 Sep; 104(6):675-6. Brady MJ, Saltiel AR. PMID: 10491401; PMCID: PMC408446.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    151. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med. 1999 Jul; 5(7):810-6. Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, Tecle H, Barrett SD, Bridges A, Przybranowski S, Leopold WR, Saltiel AR. PMID: 10395327.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    152. Lipotransin: a novel docking protein for hormone-sensitive lipase. Mol Cell. 1999 Jul; 4(1):109-15. Syu LJ, Saltiel AR. PMID: 10445032.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    153. Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. J Biol Chem. 1999 Jun 18; 274(25):17742-7. Kao AW, Noda Y, Johnson JH, Pessin JE, Saltiel AR. PMID: 10364216.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    154. Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Mol Cell. 1999 Jun; 3(6):751-60. Min J, Okada S, Kanzaki M, Elmendorf JS, Coker KJ, Ceresa BP, Syu LJ, Noda Y, Saltiel AR, Pessin JE. PMID: 10394363.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    155. Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients. Diabetes. 1999 Feb; 48(2):403-7. Hansen L, Fjordvang H, Rasmussen SK, Vestergaard H, Echwald SM, Hansen T, Alessi D, Shenolikar S, Saltiel AR, Barbetti F, Pedersen O. PMID: 10334321.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    156. The functional role of CrkII in actin cytoskeleton organization and mitogenesis. J Biol Chem. 1999 Jan 29; 274(5):3001-8. Nakashima N, Rose DW, Xiao S, Egawa K, Martin SS, Haruta T, Saltiel AR, Olefsky JM. PMID: 9915838.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    157. Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14751-6. Ribon V, Johnson JH, Camp HS, Saltiel AR. PMID: 9843961; PMCID: PMC24521.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    158. The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells. J Biol Chem. 1998 Jun 05; 273(23):14063-6. Brady MJ, Bourbonais FJ, Saltiel AR. PMID: 9603900.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    159. Spatial determinants of specificity in insulin action. Mol Cell Biochem. 1998 May; 182(1-2):65-71. Mastick CC, Brady MJ, Printen JA, Ribon V, Saltiel AR. PMID: 9609115.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    160. Troglitazone increases system A amino acid transport in 3T3-L1 cells. Endocrinology. 1998 Mar; 139(3):832-7. Su TZ, Wang M, Oxender DL, Saltiel AR. PMID: 9492010.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    161. A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions. J Biol Chem. 1998 Feb 13; 273(7):4073-80. Ribon V, Herrera R, Kay BK, Saltiel AR. PMID: 9461600.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    162. Regulation of system A amino acid transport in 3T3-L1 adipocytes by insulin. J Biol Chem. 1998 Feb 06; 273(6):3173-9. Su TZ, Wang M, Syu LJ, Saltiel AR, Oxender DL. PMID: 9452428.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    163. A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Mol Cell Biol. 1998 Feb; 18(2):872-9. Ribon V, Printen JA, Hoffman NG, Kay BK, Saltiel AR. PMID: 9447983; PMCID: PMC108798.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    164. Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade. J Neurochem. 1998 Feb; 70(2):524-30. Desdouits-Magnen J, Desdouits F, Takeda S, Syu LJ, Saltiel AR, Buxbaum JD, Czernik AJ, Nairn AC, Greengard P. PMID: 9453546.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    165. Importance of MEK in neutrophil microbicidal responsiveness. J Immunol. 1998 Jan 01; 160(1):434-43. Downey GP, Butler JR, Tapper H, Fialkow L, Saltiel AR, Rubin BB, Grinstein S. PMID: 9552001.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    166. Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells. J Cell Biochem. 1997 Dec 01; 67(3):367-77. Syu LJ, Guan KL, Saltiel AR. PMID: 9361191.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    167. The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action. J Biol Chem. 1997 Nov 21; 272(47):29698-703. Brady MJ, Nairn AC, Saltiel AR. PMID: 9368038.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    168. Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5. Mol Cell Endocrinol. 1997 Oct 20; 133(2):169-76. Pircher TJ, Flores-Morales A, Mui AL, Saltiel AR, Norstedt G, Gustafsson JA, Haldosén LA. PMID: 9406863.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    169. Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation. J Biol Chem. 1997 Aug 22; 272(34):21268-73. Kim B, Leventhal PS, Saltiel AR, Feldman EL. PMID: 9261137.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    170. Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. J Biol Chem. 1997 Aug 15; 272(33):20706-14. Mastick CC, Saltiel AR. PMID: 9252391.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    171. Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity. J Biol Chem. 1997 Aug 08; 272(32):20198-204. Brady MJ, Printen JA, Mastick CC, Saltiel AR. PMID: 9242697.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    172. Proliferin induces endothelial cell chemotaxis through a G protein-coupled, mitogen-activated protein kinase-dependent pathway. Endocrinology. 1997 Jul; 138(7):2835-40. Groskopf JC, Syu LJ, Saltiel AR, Linzer DI. PMID: 9202225.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    173. Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes. Biochem J. 1997 Jun 15; 324 ( Pt 3):839-45. Ribon V, Saltiel AR. PMID: 9210408; PMCID: PMC1218500.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    174. PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism. Science. 1997 Mar 07; 275(5305):1475-8. Printen JA, Brady MJ, Saltiel AR. PMID: 9045612.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    175. Negative modulation of membrane localization of the Raf-1 protein kinase by hyperphosphorylation. J Biol Chem. 1997 Feb 14; 272(7):3915-23. Wartmann M, Hofer P, Turowski P, Saltiel AR, Hynes NE. PMID: 9020094.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    176. Metabolic effects of troglitazone in the Goto-Kakizaki rat, a non-obese and normolipidemic rodent model of non-insulin-dependent diabetes mellitus. Metabolism. 1997 Feb; 46(2):192-8. O'Rourke CM, Davis JA, Saltiel AR, Cornicelli JA. PMID: 9030828.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    177. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways. J Biol Chem. 1997 Jan 03; 272(1):154-61. Párrizas M, Saltiel AR, LeRoith D. PMID: 8995241.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    178. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 1996 Dec; 45(12):1661-9. Saltiel AR, Olefsky JM. PMID: 8922349.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimals
    179. Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown. Endocrinology. 1996 Nov; 137(11):5045-54. Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM. PMID: 8895379.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    180. Targeting signal transduction in the discovery of antiproliferative drugs. Chem Biol. 1996 Nov; 3(11):887-93. Saltiel AR, Sawyer TK. PMID: 8939707.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    181. Protein tyrosine phosphatase 1B interacts with the activated insulin receptor. Diabetes. 1996 Oct; 45(10):1379-85. Seely BL, Staubs PA, Reichart DR, Berhanu P, Milarski KL, Saltiel AR, Kusari J, Olefsky JM. PMID: 8826975.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    182. Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain. Biochemistry. 1996 Sep 10; 35(36):11852-64. Thornton KH, Mueller WT, McConnell P, Zhu G, Saltiel AR, Thanabal V. PMID: 8794768.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    183. Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C. J Biol Chem. 1996 May 31; 271(22):12891-6. Morrison P, Saltiel AR, Rosner MR. PMID: 8662819.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    184. Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex. J Biol Chem. 1996 Apr 05; 271(14):8300-6. Holt KH, Waters SB, Okada S, Yamauchi K, Decker SJ, Saltiel AR, Motto DG, Koretzky GA, Pessin JE. PMID: 8626525.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    185. Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells. J Biol Chem. 1996 Mar 29; 271(13):7375-80. Ribon V, Saltiel AR. PMID: 8631760.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    186. Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways. J Biol Chem. 1996 Mar 01; 271(9):5033-9. Azpiazu I, Saltiel AR, DePaoli-Roach AA, Lawrence JC. PMID: 8617780.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    187. Diverse signaling pathways in the cellular actions of insulin. Am J Physiol. 1996 Mar; 270(3 Pt 1):E375-85. Saltiel AR. PMID: 8638681.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    188. Structural and functional roles of glycosylphosphoinositides. Subcell Biochem. 1996; 26:165-85. Saltiel AR. PMID: 8744265.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    189. The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner. Mol Cell Biol. 1996 Jan; 16(1):45-52. Ribon V, Hubbell S, Herrera R, Saltiel AR. PMID: 8524328; PMCID: PMC230977.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    190. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem. 1995 Nov 17; 270(46):27489-94. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PMID: 7499206.
      View in: PubMed   Mentions: 636     Fields:    Translation:HumansAnimalsCells
    191. Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation. J Biol Chem. 1995 Oct 27; 270(43):25320-3. Langlois WJ, Sasaoka T, Saltiel AR, Olefsky JM. PMID: 7592690.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    192. Expression of a catalytically inert Syp blocks activation of MAP kinase pathway downstream of p21ras. Biochem Biophys Res Commun. 1995 Sep 14; 214(2):737-43. Sawada T, Milarski KL, Saltiel AR. PMID: 7677789.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    193. Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex. J Biol Chem. 1995 Sep 08; 270(36):20883-6. Waters SB, Holt KH, Ross SE, Syu LJ, Guan KL, Saltiel AR, Koretzky GA, Pessin JE. PMID: 7673108.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    194. Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. J Biol Chem. 1995 Sep 01; 270(35):20801-7. Lazar DF, Wiese RJ, Brady MJ, Mastick CC, Waters SB, Yamauchi K, Pessin JE, Cuatrecasas P, Saltiel AR. PMID: 7657664.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    195. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A. 1995 Aug 15; 92(17):7686-9. Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. PMID: 7644477; PMCID: PMC41210.
      View in: PubMed   Mentions: 501     Fields:    Translation:HumansAnimalsCells
    196. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein. J Biol Chem. 1995 Aug 11; 270(32):19151-7. Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM. PMID: 7642582.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    197. Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. J Biol Chem. 1995 Aug 04; 270(31):18531-8. Lin TA, Kong X, Saltiel AR, Blackshear PJ, Lawrence JC. PMID: 7629182.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    198. Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin. J Biol Chem. 1995 Jul 28; 270(30):17716-22. Yamauchi K, Ribon V, Saltiel AR, Pessin JE. PMID: 7629070.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    199. Signal transduction pathways leading to insulin-induced early gene induction. Biochemistry. 1995 Jun 27; 34(25):7996-8004. Jhun BH, Haruta T, Meinkoth JL, Leitner W, Draznin B, Saltiel AR, Pang L, Sasaoka T, Olefsky JM. PMID: 7540866.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    200. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem. 1995 Jun 09; 270(23):13585-8. Pang L, Sawada T, Decker SJ, Saltiel AR. PMID: 7775407.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    201. Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain of phosphatidylinositol 3-kinase. Biochem J. 1995 Jun 01; 308 ( Pt 2):579-83. Milarski KL, Lazar DF, Wiese RJ, Saltiel AR. PMID: 7539611; PMCID: PMC1136965.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    202. Insulin stimulates the tyrosine phosphorylation of caveolin. J Cell Biol. 1995 Jun; 129(6):1523-31. Mastick CC, Brady MJ, Saltiel AR. PMID: 7540611; PMCID: PMC2291186.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    203. Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK). Biochem J. 1995 Apr 15; 307 ( Pt 2):513-9. Pang L, Zheng CF, Guan KL, Saltiel AR. PMID: 7733891; PMCID: PMC1136678.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
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