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Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis. J Pediatr Gastroenterol Nutr. 2024 Sep 16.
Jain AK, Busgang SA, Gennings C, Yates KP, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Carpenter D, Fishbein M, Neuschwander-Tetri BA, Tonasia J, Vos MB. PMID: 39282813.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
-
Pentadecanoic Acid Supplementation in Young Adults with Overweight and Obesity: A Randomized Controlled Trial. J Nutr. 2024 Sep; 154(9):2763-2771.
Robinson MK, Lee E, Ugalde-Nicalo PA, Skonieczny JW, Chun LF, Newton KP, Schwimmer JB. PMID: 39069269.
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PubMed Mentions: Fields:
Translation:
Humans
-
Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity. J Pediatr Gastroenterol Nutr. 2024 Aug; 79(2):238-249.
Mouzaki M, Yates KP, Arce-Clachar AC, Behling C, Blondet NM, Fishbein MH, Flores F, Adams KH, Hertel P, Jain AK, Molleston JP, Schwimmer JB, Vos MB, Xanthakos SA, NASH Clinical Research Network. PMID: 38828720.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Patient perspective on exercise practices, preferences, and barriers in pediatric nonalcoholic fatty liver disease: A multicenter survey. JPGN Rep. 2024 Aug; 5(3):317-325.
Yu EL, You H, Rudolph B, Panganiban JA, Kohut TJ, Lin HC, Fifi AC, Budhathoki R, Butler MW, Anderson SR, Goyal NP, Newton KP, Schwimmer JB. PMID: 39149177; PMCID: PMC11322029.
View in:
PubMed Mentions:
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Lipidome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys with Metabolic Dysfunction-Associated Steatotic Liver Disease. Metabolites. 2024 Mar 28; 14(4).
Huneault HE, Chen CY, Cohen CC, Liu X, Jarrell ZR, He Z, DeSantos KE, Welsh JA, Maner-Smith KM, Ortlund EA, Schwimmer JB, Vos MB. PMID: 38668319; PMCID: PMC11052520.
View in:
PubMed Mentions:
1
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Alanine aminotransferase elevation varies by ethnicity among Asian and Pacific Islander children with overweight or obesity. Pediatr Obes. 2024 Jun; 19(6):e13110.
Lee C, Schwimmer JB, Gunderson EP, Goyal NP, Darbinian JA, Greenspan LC, Lo JC. PMID: 38444225.
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PubMed Mentions: Fields:
Translation:
Humans
-
Prevalence of Adolescents Meeting Criteria for Metabolic and Bariatric Surgery. Pediatrics. 2024 Mar 01; 153(3).
Shapiro WL, Kunani P, Sidell MA, Li X, Anderson SR, Slezak JM, Koebnick C, Schwimmer JB. PMID: 38410833.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Letter to the editor in response to: A case of pediatric alcohol-associated hepatitis evaluated for liver transplant listing. JPGN Rep. 2024 May; 5(2):235.
Hildreth A, Schwimmer JB. PMID: 38756136; PMCID: PMC11093891.
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PubMed Mentions:
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A serum-induced gene signature in hepatocytes is associated with pediatric nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2024 Apr; 78(4):886-897.
Hang Nghiem-Rao T, Johnson JS, Pan A, Atkinson SN, Behling C, Simpson PM, Holtz ML, Weinstock GM, Schwimmer JB, Salzman NH. PMID: 38390691.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Reply to letter to the editor in response to: Distinguishing autoimmune hepatitis from steatohepatitis in adolescents with obesity and positive screening alanine aminotransferase. JPGN Rep. 2024 May; 5(2):240-241.
Hildreth A, Schwimmer JB. PMID: 38756115; PMCID: PMC11093905.
View in:
PubMed Mentions:
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Age, BMI, and Type 2 Diabetes Modify the Relationship Between PNPLA3 and Advanced Fibrosis in Children and Adults With NAFLD. Clin Gastroenterol Hepatol. 2024 May; 22(5):1024-1036.e2.
Jarasvaraparn C, Vilar-Gomez E, Yates KP, Wilson LA, Neuschwander-Tetri B, Loomba R, Cummings O, Vos M, Xanthakos S, Schwimmer J, Molleston JP, Sanyal A, Tonascia J, Chalasani N. PMID: 38145725; PMCID: PMC11045318.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Nutrition assessment and MASH severity in children using the Healthy Eating Index. Hepatol Commun. 2023 12 01; 7(12).
Jain AK, Buchannan P, Yates KP, Belt P, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Hertel P, Nilson J, Neuschwander-Tetri BA, Tonascia J, Vos MB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 38055641; PMCID: PMC10984667.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Development of Fibro-PeN, a clinical prediction model for moderate-to-severe fibrosis in children with nonalcoholic fatty liver disease. Hepatology. 2024 06 01; 79(6):1381-1392.
Wang A, Blackford AL, Behling C, Wilson LA, Newton KP, Xanthakos SA, Fishbein MH, Vos MB, Mouzaki M, Molleston JP, Jain AK, Hertel P, Harlow Adams K, Schwimmer JB, NASH CRN. PMID: 37870272; PMCID: PMC11035485.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Prevalence of Elevated ALT in Adolescents in the US 2011-2018. J Pediatr Gastroenterol Nutr. 2023 07 01; 77(1):103-109.
Mischel AK, Liao Z, Cao F, Dunn W, Lo JC, Newton KP, Goyal NP, Yu EL, Schwimmer JB. PMID: 37084344; PMCID: PMC10330162.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
An Open Label, Randomized, Multicenter Study of Elafibranor in Children With Nonalcoholic Steatohepatitis. J Pediatr Gastroenterol Nutr. 2023 08 01; 77(2):160-165.
Goyal NP, Mencin A, Newton KP, Durelle J, Carrier C, Ugalde-Nicalo P, Noel B, Mouton J, Vargas D, Magrez D, Tadde B, Birman P, Best BM, Addy C, Schwimmer JB. PMID: 37084342; PMCID: PMC10523882.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Association of Hepatic Steatosis with Adipose and Muscle Mass and Distribution in Children. Metab Syndr Relat Disord. 2023 05; 21(4):222-230.
Malki GJ, Goyal NP, Ugalde-Nicalo P, Chun LF, Zhang J, Ding Z, Wei Y, Knott C, Batakis D, Henderson W, Sirlin CB, Middleton MS, Schwimmer JB. PMID: 37083405; PMCID: PMC10181799.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Metabolome × Microbiome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys. Metabolites. 2023 Mar 08; 13(3).
Cohen CC, Huneault H, Accardi CJ, Jones DP, Liu K, Maner-Smith KM, Song M, Welsh JA, Ugalde-Nicalo PA, Schwimmer JB, Vos MB. PMID: 36984841; PMCID: PMC10053986.
View in:
PubMed Mentions:
1
-
Distinguishing Autoimmune Hepatitis From Steatohepatitis in Adolescents With Obesity and Positive Screening Alanine Aminotransferase. JPGN Rep. 2023 May; 4(2):e292.
Hildreth A, Shapiro WL, Lowenthal BM, Goyal A, Schwimmer JB. PMID: 37200725; PMCID: PMC10187841.
View in:
PubMed Mentions:
2
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Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. Hepatology. 2023 01 01; 77(1):197-212.
Goyal NP, Rosenthal SB, Nasamran C, Behling CA, Angeles JE, Fishbein MH, Harlow KE, Jain AK, Molleston JP, Newton KP, Ugalde-Nicalo P, Xanthankos SA, Yates K, Schork NJ, Fisch KM, Schwimmer JB, NASH Clinical Research Network. PMID: 35560106; PMCID: PMC9653518.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 05; 21(5):1261-1270.
Newton KP, Wilson LA, Crimmins NA, Fishbein MH, Molleston JP, Xanthakos SA, Behling C, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 35709934; PMCID: PMC10151072.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Nat Genet. 2022 06; 54(6):761-771.
Vujkovic M, Ramdas S, Lorenz KM, Guo X, Darlay R, Cordell HJ, He J, Gindin Y, Chung C, Myers RP, Schneider CV, Park J, Lee KM, Serper M, Carr RM, Kaplan DE, Haas ME, MacLean MT, Witschey WR, Zhu X, Tcheandjieu C, Kember RL, Kranzler HR, Verma A, Giri A, Klarin DM, Sun YV, Huang J, Huffman JE, Creasy KT, Hand NJ, Liu CT, Long MT, Yao J, Budoff M, Tan J, Li X, Lin HJ, Chen YI, Taylor KD, Chang RK, Krauss RM, Vilarinho S, Brancale J, Nielsen JB, Locke AE, Jones MB, Verweij N, Baras A, Reddy KR, Neuschwander-Tetri BA, Schwimmer JB, Sanyal AJ, Chalasani N, Ryan KA, Mitchell BD, Gill D, Wells AD, Manduchi E, Saiman Y, Mahmud N, Miller DR, Reaven PD, Phillips LS, Muralidhar S, DuVall SL, Lee JS, Assimes TL, Pyarajan S, Cho K, Edwards TL, Damrauer SM, Wilson PW, Gaziano JM, O'Donnell CJ, Khera AV, Grant SFA, Brown CD, Tsao PS, Saleheen D, Lotta LA, Bastarache L, Anstee QM, Daly AK, Meigs JB, Rotter JI, Lynch JA, Regeneron Genetics Center, Geisinger-Regeneron DiscovEHR Collaboration, EPoS Consortium, VA Million Veteran Program, Rader DJ, Voight BF, Chang KM. PMID: 35654975; PMCID: PMC10024253.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Randomized placebo-controlled trial of losartan for pediatric NAFLD. Hepatology. 2022 08; 76(2):429-444.
Vos MB, Van Natta ML, Blondet NM, Dasarathy S, Fishbein M, Hertel P, Jain AK, Karpen SJ, Lavine JE, Mohammad S, Miriel LA, Molleston JP, Mouzaki M, Sanyal A, Sharkey EP, Schwimmer JB, Tonascia J, Wilson LA, Xanthakos SA, NASH Clinical Research Network. PMID: 35133671; PMCID: PMC9288975.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease. J Clin Invest. 2021 12 15; 131(24).
Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB. PMID: 34907907; PMCID: PMC8670836.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCellsCTClinical Trials
-
The Prevalence of Elevated Alanine Aminotransferase Levels Meeting Clinical Action Thresholds in Children with Obesity in Primary Care Practice. J Pediatr. 2022 01; 240:280-283.
Wu SJ, Darbinian JA, Schwimmer JB, Yu EL, Ramalingam ND, Greenspan LC, Lo JC. PMID: 34562443; PMCID: PMC8841387.
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PubMed Mentions: Fields:
Translation:
Humans
-
Recent advances in the epidemiology of nonalcoholic fatty liver disease in children. Pediatr Obes. 2021 11; 16(11):e12849.
Shapiro WL, Noon SL, Schwimmer JB. PMID: 34498413; PMCID: PMC8807003.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Pediatric nonalcoholic fatty liver disease and the microbiome: Mechanisms contributing to pathogenesis and progression. Curr Opin Endocr Metab Res. 2021 Aug; 19:22-29.
Salzman NH, Schwimmer JB. PMID: 34222711; PMCID: PMC8248528.
View in:
PubMed Mentions:
2
-
Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis. Eur Radiol. 2021 Nov; 31(11):8408-8419.
Qu Y, Middleton MS, Loomba R, Glaser KJ, Chen J, Hooker JC, Wolfson T, Covarrubias Y, Valasek MA, Fowler KJ, Zhang YN, Sy E, Gamst AC, Wang K, Mamidipalli A, Schwimmer JB, Song B, Reeder SB, Yin M, Ehman RL, Sirlin CB. PMID: 33899143; PMCID: PMC8530863.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Epidemiology of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis (Hoboken). 2021 Mar; 17(3):196-199.
Yu EL, Schwimmer JB. PMID: 33868665; PMCID: PMC8043694.
View in:
PubMed Mentions:
34
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Incidence of Depression and Anxiety in a Cohort of Adolescents With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2021 04 01; 72(4):579-583.
Noon SL, D'Annibale DA, Schwimmer MH, Shiels J, Arin J, Durelle J, Newton KP, Goyal NP, Schwimmer JB. PMID: 33346572; PMCID: PMC8815421.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children. J Pediatr Gastroenterol Nutr. 2021 04 01; 72(4):e90-e96.
Sawh MC, Wallace M, Shapiro E, Goyal NP, Newton KP, Yu EL, Bross C, Durelle J, Knott C, Gangoiti JA, Barshop BA, Gengatharan JM, Meurs N, Schlein A, Middleton MS, Sirlin CB, Metallo CM, Schwimmer JB. PMID: 33399331; PMCID: PMC8842839.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Abdom Radiol (NY). 2021 07; 46(7):3105-3116.
Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. PMID: 33609166; PMCID: PMC8983333.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Hepatic Steatosis is Negatively Associated with Bone Mineral Density in Children. J Pediatr. 2021 06; 233:105-111.e3.
Chun LF, Yu EL, Sawh MC, Bross C, Nichols J, Polgreen L, Knott C, Schlein A, Sirlin CB, Middleton MS, Kado DM, Schwimmer JB. PMID: 33545191; PMCID: PMC8154638.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Incidence of Nonalcoholic Fatty Liver Disease in Children: 2009-2018. Pediatrics. 2020 12; 146(6).
Sahota AK, Shapiro WL, Newton KP, Kim ST, Chung J, Schwimmer JB. PMID: 33214329; PMCID: PMC7706110.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. Hepatology. 2021 03; 73(3):937-951.
Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 32416645; PMCID: PMC7669708.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice. Gastroenterology. 2020 11; 159(5):1731-1751.e10.
Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J, NASH Clinical Research Network. PMID: 32712103; PMCID: PMC7680281.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Prospective comparison of longitudinal change in hepatic proton density fat fraction (PDFF) estimated by magnitude-based MRI (MRI-M) and complex-based MRI (MRI-C). Eur Radiol. 2020 Sep; 30(9):5120-5129.
Mamidipalli A, Fowler KJ, Hamilton G, Wolfson T, Covarrubias Y, Tran C, Fazeli S, Wiens CN, McMillan A, Artz NS, Funk LM, Campos GM, Greenberg JA, Gamst A, Middleton MS, Schwimmer JB, Reeder SB, Sirlin CB. PMID: 32318847; PMCID: PMC7495399.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Accuracy of common proton density fat fraction thresholds for magnitude- and complex-based chemical shift-encoded MRI for assessing hepatic steatosis in patients with obesity. Abdom Radiol (NY). 2020 03; 45(3):661-671.
Cunha GM, Thai TT, Hamilton G, Covarrubias Y, Schlein A, Middleton MS, Wiens CN, McMillan A, Agni R, Funk LM, Campos GM, Horgan S, Jacobson G, Wolfson T, Gamst A, Schwimmer JB, Reeder SB, Sirlin CB. PMID: 31781899; PMCID: PMC8108484.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Evaluation of Quantitative Imaging Biomarkers for Early-phase Clinical Trials of Steatohepatitis in Adolescents. J Pediatr Gastroenterol Nutr. 2020 01; 70(1):99-105.
Goyal NP, Sawh MC, Ugalde-Nicalo P, Angeles JE, Proudfoot JA, Newton KP, Middleton MS, Sirlin CB, Schwimmer JB. PMID: 31633654; PMCID: PMC8053386.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. J Clin Gastroenterol. 2019 Nov/Dec; 53(10):750-758.
Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 30586008; PMCID: PMC6588507.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Measurement of spleen fat on MRI-proton density fat fraction arises from reconstruction of noise. Abdom Radiol (NY). 2019 10; 44(10):3295-3303.
Hong CW, Hamilton G, Hooker C, Park CC, Tran CA, Henderson WC, Hooker JC, Fazeli Dehkordy S, Schwimmer JB, Reeder SB, Sirlin CB. PMID: 31172210; PMCID: PMC7275729.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease. Gastroenterology. 2019 12; 157(6):1448-1456.e1.
Vos MB, Dimick-Santos L, Mehta R, Omokaro SO, Taminiau J, Schabel E, Kleiner DE, Szitanyi P, Socha P, Schwimmer JB, Noviello S, Silberg DG, Torstenson R, Miller V, Lavine JE, Liver Forum Pediatric Working Group. PMID: 31520612; PMCID: PMC8996263.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Normal range for MR elastography measured liver stiffness in children without liver disease. J Magn Reson Imaging. 2020 03; 51(3):919-927.
Sawh MC, Newton KP, Goyal NP, Angeles JE, Harlow K, Bross C, Schlein AN, Hooker JC, Sy EZ, Glaser KJ, Yin M, Ehman RL, Sirlin CB, Schwimmer JB. PMID: 31452280; PMCID: PMC7386297.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2019 10; 157(4):1109-1122.
Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH. PMID: 31255652; PMCID: PMC6756995.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansCells
-
Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):182-189.
Shapiro WL, Yu EL, Arin JC, Murray KF, Ali S, Desai NK, Xanthakos SA, Lin HC, Alkhouri N, Abdou R, Abrams SH, Butler MW, Faasse SA, Gillis LA, Hadley TA, Jain AK, Kavan M, Kordy K, Lee P, Panganiban J, Pohl JF, Potter C, Rudolph B, Sundaram SS, Joshi S, Proudfoot JA, Goyal NP, Harlow KE, Newton KP, Schwimmer JB. PMID: 30640271; PMCID: PMC8053385.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Pilot study on longitudinal change in pancreatic proton density fat fraction during a weight-loss surgery program in adults with obesity. J Magn Reson Imaging. 2019 10; 50(4):1092-1102.
Covarrubias Y, Fowler KJ, Mamidipalli A, Hamilton G, Wolfson T, Leinhard OD, Jacobsen G, Horgan S, Schwimmer JB, Reeder SB, Sirlin CB. PMID: 30701611; PMCID: PMC6667307.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial. JAMA. 2019 01 22; 321(3):256-265.
Schwimmer JB, Ugalde-Nicalo P, Welsh JA, Angeles JE, Cordero M, Harlow KE, Alazraki A, Durelle J, Knight-Scott J, Newton KP, Cleeton R, Knott C, Konomi J, Middleton MS, Travers C, Sirlin CB, Hernandez A, Sekkarie A, McCracken C, Vos MB. PMID: 30667502; PMCID: PMC6440226.
View in:
PubMed Mentions:
107 Fields:
Translation:
Humans
-
Monitoring Fatty Liver Disease with MRI Following Bariatric Surgery: A Prospective, Dual-Center Study. Radiology. 2019 03; 290(3):682-690.
Pooler BD, Wiens CN, McMillan A, Artz NS, Schlein A, Covarrubias Y, Hooker J, Schwimmer JB, Funk LM, Campos GM, Greenberg JA, Jacobsen G, Horgan S, Wolfson T, Gamst AC, Sirlin CB, Reeder SB. PMID: 30561273; PMCID: PMC6394737.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity. J Pediatr. 2019 04; 207:64-70.
Yu EL, Golshan S, Harlow KE, Angeles JE, Durelle J, Goyal NP, Newton KP, Sawh MC, Hooker J, Sy EZ, Middleton MS, Sirlin CB, Schwimmer JB. PMID: 30559024; PMCID: PMC6440815.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
-
Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. Pediatr Diabetes. 2019 02; 20(1):41-47.
Newfield RS, Graves CL, Newbury RO, Schwimmer JB, Proudfoot JA, Say DS, Feldstein AE. PMID: 30467936.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Breastfeeding and NAFLD from the maternal side of the mother-infant dyad. J Hepatol. 2019 01; 70(1):13-14.
Nobili V, Schwimmer JB, Vajro P. PMID: 30414736.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
A Bibliometric Analysis of Clinical and Translational Research in Pediatric Gastroenterology From 1970 to 2017. J Pediatr Gastroenterol Nutr. 2018 11; 67(5):564-569.
Schwimmer MH, Sawh MC, Heskett KM, Goyal NP, Newton KP, Schwimmer JB. PMID: 29901549; PMCID: PMC6203653.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Hepatic R2* is more strongly associated with proton density fat fraction than histologic liver iron scores in patients with nonalcoholic fatty liver disease. J Magn Reson Imaging. 2019 05; 49(5):1456-1466.
Bashir MR, Wolfson T, Gamst AC, Fowler KJ, Ohliger M, Shah SN, Alazraki A, Trout AT, Behling C, Allende DS, Loomba R, Sanyal A, Schwimmer J, Lavine JE, Shen W, Tonascia J, Van Natta ML, Mamidipalli A, Hooker J, Kowdley KV, Middleton MS, Sirlin CB, NASH Clinical Research Network (NASH CRN). PMID: 30318834; PMCID: PMC6449180.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2018 Oct; 2(10):1213-1226.
Elbel EE, Lavine JE, Downes M, Van Natta M, Yu R, Schwimmer JB, Behling C, Brunt EM, Tonascia J, Evans R. PMID: 30288476; PMCID: PMC6167075.
View in:
PubMed Mentions:
9 Fields:
-
Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2018 05; 66(5):789-796.
Rausch JC, Lavine JE, Chalasani N, Guo X, Kwon S, Schwimmer JB, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Rotter JI, NASH Clinical Research Network. PMID: 29470286; PMCID: PMC5916321.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Assessment of a high-SNR chemical-shift-encoded MRI with complex reconstruction for proton density fat fraction (PDFF) estimation overall and in the low-fat range. J Magn Reson Imaging. 2019 01; 49(1):229-238.
Park CC, Hooker C, Hooker JC, Bass E, Haufe W, Schlein A, Covarrubias Y, Heba E, Bydder M, Wolfson T, Gamst A, Loomba R, Schwimmer J, Hernando D, Reeder SB, Middleton M, Sirlin CB, Hamilton G. PMID: 29707848; PMCID: PMC6205914.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. J Pediatr. 2018 07; 198:76-83.e2.
Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 29661561; PMCID: PMC6019181.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. Hepatology. 2018 03; 67(3):858-872.
Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin CB, NASH Clinical Research Network. PMID: 29028128; PMCID: PMC6211296.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCTClinical Trials
-
How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc. 2018 04; 32(4):1675-1682.
Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin CB, Jacobsen GR. PMID: 29218660; PMCID: PMC6690434.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. NMR Biomed. 2018 Jan; 31(1).
Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin CB. PMID: 29130539; PMCID: PMC5761676.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. Hepatology. 2017 11; 66(5):1474-1485.
Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. PMID: 28493388; PMCID: PMC5650504.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
The Genetics of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2018 02; 22(1):59-71.
Goyal NP, Schwimmer JB. PMID: 29128061; PMCID: PMC5693307.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. J Pediatr. 2017 11; 190:100-107.e2.
Wattacheril J, Lavine JE, Chalasani NP, Guo X, Kwon S, Schwimmer J, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Tonascia J, Rotter JI. PMID: 28918882; PMCID: PMC5690841.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2017 Sep; 1(7):609-622.
Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B. PMID: 29130075; PMCID: PMC5679472.
View in:
PubMed Mentions:
12 Fields:
-
Pediatric Psoriasis Comorbidity Screening Guidelines. JAMA Dermatol. 2017 07 01; 153(7):698-704.
Osier E, Wang AS, Tollefson MM, Cordoro KM, Daniels SR, Eichenfield A, Gelfand JM, Gottlieb AB, Kimball AB, Lebwohl M, Mehta NN, Paller AS, Schwimmer JB, Styne DM, Van Voorhees AS, Tom WL, Eichenfield LF. PMID: 28514463; PMCID: PMC5748031.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansPHPublic Health
-
Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 02; 47(2):418-424.
Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. PMID: 28543915; PMCID: PMC5702271.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children. J Pediatr. 2017 08; 187:141-146.e1.
Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 28366357; PMCID: PMC5533631.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. J Magn Reson Imaging. 2017 12; 46(6):1641-1647.
Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB, Sirlin CB. PMID: 28323377; PMCID: PMC5608618.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clin Gastroenterol Hepatol. 2018 03; 16(3):438-446.e1.
Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 28286193; PMCID: PMC5589478.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
-
Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study. J Magn Reson Imaging. 2017 10; 46(4):1149-1158.
Manning P, Murphy P, Wang K, Hooker J, Wolfson T, Middleton MS, Newton KP, Behling C, Awai HI, Durelle J, Paiz MN, Angeles JE, De La Pena D, McCutchan JA, Schwimmer JB, Sirlin CB. PMID: 28225568; PMCID: PMC5568908.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). J Pediatr Gastroenterol Nutr. 2017 02; 64(2):319-334.
Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. PMID: 28107283; PMCID: PMC5413933.
View in:
PubMed Mentions:
380 Fields:
Translation:
Humans
-
Bone marrow fat content is correlated with hepatic fat content in paediatric non-alcoholic fatty liver disease. Clin Radiol. 2017 May; 72(5):425.e9-425.e14.
Yu NY, Wolfson T, Middleton MS, Hamilton G, Gamst A, Angeles JE, Schwimmer JB, Sirlin CB. PMID: 28063601; PMCID: PMC5376517.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Race/ethnic and sex disparities in the non-alcoholic fatty liver disease-abdominal aortic calcification association: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2017 03; 258:89-96.
Remigio-Baker RA, Allison MA, Forbang NI, Loomba R, Anderson CAM, Budoff M, Schwimmer JB, Blumenthal RS, Ouyang P, Criqui MH. PMID: 28235711; PMCID: PMC5502083.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. JAMA Pediatr. 2016 Oct 03; 170(10):e161971.
Newton KP, Hou J, Crimmins NA, Lavine JE, Barlow SE, Xanthakos SA, Africa J, Behling C, Donithan M, Clark JM, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 27478956; PMCID: PMC5479314.
View in:
PubMed Mentions:
111 Fields:
Translation:
Humans
-
In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. Gastroenterology. 2016 12; 151(6):1141-1154.e9.
Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E, NASH CRN. PMID: 27569726; PMCID: PMC5124386.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCTClinical Trials
-
Lifestyle Interventions Including Nutrition, Exercise, and Supplements for Nonalcoholic Fatty Liver Disease in Children. Dig Dis Sci. 2016 May; 61(5):1375-86.
Africa JA, Newton KP, Schwimmer JB. PMID: 27041377; PMCID: PMC4848041.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Comparison of the Phenotype and Approach to Pediatric vs Adult Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2016 Jun; 150(8):1798-810.
Nobili V, Alisi A, Newton KP, Schwimmer JB. PMID: 27003600; PMCID: PMC4887388.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Clinical advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2016 May; 63(5):1718-25.
Schwimmer JB. PMID: 27100147; PMCID: PMC4843821.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). J Pediatr. 2016 05; 172:9-13.
Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB. PMID: 26749112; PMCID: PMC4846502.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2016 May; 20(2):325-38.
Goyal NP, Schwimmer JB. PMID: 27063272; PMCID: PMC4829737.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
-
Intra- and inter-examination repeatability of magnetic resonance spectroscopy, magnitude-based MRI, and complex-based MRI for estimation of hepatic proton density fat fraction in overweight and obese children and adults. Abdom Imaging. 2015 Oct; 40(8):3070-7.
Tyagi A, Yeganeh O, Levin Y, Hooker JC, Hamilton GC, Wolfson T, Gamst A, Zand AK, Heba E, Loomba R, Schwimmer J, Middleton MS, Sirlin CB. PMID: 26350282; PMCID: PMC4819976.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease. Abdom Imaging. 2015 Oct; 40(8):3084-90.
Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS. PMID: 26205992; PMCID: PMC4630122.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Nonalcoholic Fatty Liver Disease in Latinos. Clin Gastroenterol Hepatol. 2016 Jan; 14(1):5-12; quiz e9-10.
Saab S, Manne V, Nieto J, Schwimmer JB, Chalasani NP. PMID: 25976180.
View in:
PubMed Mentions:
55 Fields:
Translation:
Humans
-
Paediatric gastroenterology. On a knife-edge--weight-loss surgery for NAFLD in adolescents. Nat Rev Gastroenterol Hepatol. 2015 Jun; 12(6):316-8.
Xanthakos SA, Schwimmer JB. PMID: 25869913; PMCID: PMC4620919.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Accuracy of multiecho magnitude-based MRI (M-MRI) for estimation of hepatic proton density fat fraction (PDFF) in children. J Magn Reson Imaging. 2015 Nov; 42(5):1223-32.
Zand KA, Shah A, Heba E, Wolfson T, Hamilton G, Lam J, Chen J, Hooker JC, Gamst AC, Middleton MS, Schwimmer JB, Sirlin CB. PMID: 25847512; PMCID: PMC4592685.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015 Jun; 61(6):1887-95.
Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB. PMID: 25529941; PMCID: PMC4670559.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCTClinical Trials
-
On the origin of pediatric nonalcoholic Fatty liver disease. J Pediatr Gastroenterol Nutr. 2015 Feb; 60(2):147-8.
Ugalde-Nicalo PA, Schwimmer JB. PMID: 25373858; PMCID: PMC4308480.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1.5T and 3T in obese subjects. J Magn Reson Imaging. 2015 Sep; 42(3):811-7.
Artz NS, Haufe WM, Hooker CA, Hamilton G, Wolfson T, Campos GM, Gamst AC, Schwimmer JB, Sirlin CB, Reeder SB. PMID: 25620624; PMCID: PMC4803480.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease. PLoS One. 2014; 9(11):e112569.
Schwimmer JB, Zepeda A, Newton KP, Xanthakos SA, Behling C, Hallinan EK, Donithan M, Tonascia J, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 25419656; PMCID: PMC4242611.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Liver toxicity of anabolic androgenic steroid use in an adolescent with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):e32-3.
Awai HI, Yu EL, Ellis LS, Schwimmer JB. PMID: 23568051; PMCID: PMC3772995.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Relationship between changes in serum levels of keratin 18 and changes in liver histology in children and adults with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2014 Dec; 12(12):2121-30.e1-2.
Vuppalanchi R, Jain AK, Deppe R, Yates K, Comerford M, Masuoka HC, Neuschwander-Tetri BA, Loomba R, Brunt EM, Kleiner DE, Molleston JP, Schwimmer JB, Lavine JE, Tonascia J, Chalasani N. PMID: 24846279; PMCID: PMC4830682.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Letter: gender-associated cell-free microRNA profiles in non-alcoholic fatty liver disease--authors' reply. Aliment Pharmacol Ther. 2014 May; 39(9):999.
Newton KP, Awai HI, Feldstein AE, Schwimmer JB. PMID: 24689350.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Histological abnormalities in children with nonalcoholic fatty liver disease and normal or mildly elevated alanine aminotransferase levels. J Pediatr. 2014 Apr; 164(4):707-713.e3.
Molleston JP, Schwimmer JB, Yates KP, Murray KF, Cummings OW, Lavine JE, Brunt EM, Scheimann AO, Unalp-Arida A, NASH Clinical Research Network. PMID: 24360992; PMCID: PMC3962701.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Inter-examination precision of magnitude-based MRI for estimation of segmental hepatic proton density fat fraction in obese subjects. J Magn Reson Imaging. 2014 May; 39(5):1265-71.
Negrete LM, Middleton MS, Clark L, Wolfson T, Gamst AC, Lam J, Changchien C, Deyoung-Dominguez IM, Hamilton G, Loomba R, Schwimmer J, Sirlin CB. PMID: 24136736; PMCID: PMC3984359.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Paediatric gastroenterology evaluation of overweight and obese children referred from primary care for suspected non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Nov; 38(10):1267-77.
Schwimmer JB, Newton KP, Awai HI, Choi LJ, Garcia MA, Ellis LL, Vanderwall K, Fontanesi J. PMID: 24117728; PMCID: PMC3984047.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansPHPublic Health
-
Evidence and recommendations for imaging liver fat in children, based on systematic review. Clin Gastroenterol Hepatol. 2014 May; 12(5):765-73.
Awai HI, Newton KP, Sirlin CB, Behling C, Schwimmer JB. PMID: 24090729; PMCID: PMC3969892.
View in:
PubMed Mentions:
52 Fields:
Translation:
Humans
-
Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7.
Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. PMID: 23596052; PMCID: PMC3732566.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Clinical trials for adolescent obesity: cooking up an alphabet stew of what to do. JAMA Pediatr. 2013 Apr; 167(4):391-3.
Schwimmer JB. PMID: 23381196.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Hedgehog pathway and pediatric nonalcoholic fatty liver disease. Hepatology. 2013 May; 57(5):1814-25.
Swiderska-Syn M, Suzuki A, Guy CD, Schwimmer JB, Abdelmalek MF, Lavine JE, Diehl AM. PMID: 23300059; PMCID: PMC3637920.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
-
Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31.
Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. PMID: 23382291; PMCID: PMC3632805.
View in:
PubMed Mentions:
243 Fields:
Translation:
Humans
-
Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD). J Hepatol. 2012 Aug; 57(2):384-91.
Dunn W, Sanyal AJ, Brunt EM, Unalp-Arida A, Donohue M, McCullough AJ, Schwimmer JB. PMID: 22521357; PMCID: PMC3399018.
View in:
PubMed Mentions:
101 Fields:
Translation:
Humans
-
Choline intake in a large cohort of patients with nonalcoholic fatty liver disease. Am J Clin Nutr. 2012 Apr; 95(4):892-900.
Guerrerio AL, Colvin RM, Schwartz AK, Molleston JP, Murray KF, Diehl A, Mohan P, Schwimmer JB, Lavine JE, Torbenson MS, Scheimann AO. PMID: 22338037; PMCID: PMC3302364.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Association between puberty and features of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2012 Jul; 10(7):786-94.
Suzuki A, Abdelmalek MF, Schwimmer JB, Lavine JE, Scheimann AO, Unalp-Arida A, Yates KP, Sanyal AJ, Guy CD, Diehl AM, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 22343513; PMCID: PMC3382041.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. J Pediatr Gastroenterol Nutr. 2012 Jan; 54(1):90-6.
Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE, NASH CRN Research Group. PMID: 22197855; PMCID: PMC3208079.
View in:
PubMed Mentions:
52 Fields:
Translation:
Humans
-
Non-alcoholic fatty liver disease is associated with low bone mineral density in obese children. Aliment Pharmacol Ther. 2012 Jan; 35(2):248-54.
Pardee PE, Dunn W, Schwimmer JB. PMID: 22111971; PMCID: PMC4624396.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA. 2011 Apr 27; 305(16):1659-68.
Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 21521847; PMCID: PMC3110082.
View in:
PubMed Mentions:
417 Fields:
Translation:
Humans
-
Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2011 May; 33(9):1036-44.
Dohil R, Schmeltzer S, Cabrera BL, Wang T, Durelle J, Duke KB, Schwimmer JB, Lavine JE. PMID: 21395631.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):198-202.
Barshop NJ, Capparelli EV, Sirlin CB, Schwimmer JB, Lavine JE. PMID: 21240014; PMCID: PMC3059772.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology. 2011 Mar; 258(3):749-59.
Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB. PMID: 21212366; PMCID: PMC3042639.
View in:
PubMed Mentions:
157 Fields:
Translation:
Humans
-
Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol. 2011 Mar; 106(3):460-8; quiz 469.
Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB, NASH CRN Research Group. PMID: 21206486; PMCID: PMC3070294.
View in:
PubMed Mentions:
129 Fields:
Translation:
Humans
-
Adenovirus 36 and obesity in children and adolescents. Pediatrics. 2010 Oct; 126(4):721-6.
Gabbert C, Donohue M, Arnold J, Schwimmer JB. PMID: 20855385.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. Am J Gastroenterol. 2010 Sep; 105(9):2093-102.
Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, Sanyal AJ, Schwimmer JB, Lavine JE. PMID: 20372110; PMCID: PMC3070291.
View in:
PubMed Mentions:
56 Fields:
Translation:
Humans
-
SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology. 2010 Apr; 138(4):1357-64, 1364.e1-2.
Schwimmer JB, Dunn W, Norman GJ, Pardee PE, Middleton MS, Kerkar N, Sirlin CB. PMID: 20064512; PMCID: PMC2846968.
View in:
PubMed Mentions:
173 Fields:
Translation:
Humans
-
Pediatric nonalcoholic fatty liver disease: a comprehensive review. Adv Pediatr. 2010; 57(1):85-140.
Lindbäck SM, Gabbert C, Johnson BL, Smorodinsky E, Sirlin CB, Garcia N, Pardee PE, Kistler KD, Schwimmer JB. PMID: 21056736.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Symptoms and quality of life in obese children and adolescents with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2010 Feb 01; 31(3):396-406.
Kistler KD, Molleston J, Unalp A, Abrams SH, Behling C, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 19863497; PMCID: PMC2807909.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2009 Oct; 50(4):1282-93.
Loomba R, Sirlin CB, Schwimmer JB, Lavine JE. PMID: 19637286; PMCID: PMC2757471.
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PubMed Mentions:
96 Fields:
Translation:
Humans
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Treatment of nonalcoholic fatty liver disease in children: TONIC trial design. Contemp Clin Trials. 2010 Jan; 31(1):62-70.
Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J, Nonalcoholic Steatohepatitis Clinical Research Network Research Group. PMID: 19761871; PMCID: PMC2936451.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery. Semin Pediatr Surg. 2009 Aug; 18(3):144-51.
Pardee PE, Lavine JE, Schwimmer JB. PMID: 19573756; PMCID: PMC2761012.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging. 2009 Jul; 30(1):145-52.
Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB. PMID: 19557733; PMCID: PMC2982807.
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PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Nonalcoholic fatty liver disease as a comorbidity of childhood obesity. Ped Health. 2009 Jun 01; 3(3):271-281.
Barshop NJ, Francis CS, Schwimmer JB, Lavine JE. PMID: 20556232; PMCID: PMC2885801.
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PubMed Mentions:
17
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Quality of life in adults with nonalcoholic fatty liver disease: baseline data from the nonalcoholic steatohepatitis clinical research network. Hepatology. 2009 Jun; 49(6):1904-12.
David K, Kowdley KV, Unalp A, Kanwal F, Brunt EM, Schwimmer JB, NASH CRN Research Group. PMID: 19434741; PMCID: PMC2692572.
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PubMed Mentions:
73 Fields:
Translation:
Humans
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Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology. 2009 Apr; 251(1):67-76.
Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB. PMID: 19221054; PMCID: PMC2663579.
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PubMed Mentions:
165 Fields:
Translation:
Humans
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Heritability of nonalcoholic fatty liver disease. Gastroenterology. 2009 May; 136(5):1585-92.
Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB. PMID: 19208353; PMCID: PMC3397140.
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PubMed Mentions:
182 Fields:
Translation:
Humans
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Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics. 2009 Jan-Feb; 29(1):231-60.
Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB. PMID: 19168847.
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PubMed Mentions:
98 Fields:
Translation:
Humans
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Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment. Obesity (Silver Spring). 2008 Dec; 16(12):2566-77.
Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB. PMID: 19279654.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment: a consensus statement of Shaping America's Health and the Obesity Society. Diabetes Care. 2008 Nov; 31(11):2211-21.
Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB. PMID: 18955718; PMCID: PMC2571048.
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PubMed Mentions:
129 Fields:
Translation:
Humans
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Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease. Semin Liver Dis. 2008 Nov; 28(4):380-5.
Rubinstein E, Lavine JE, Schwimmer JB. PMID: 18956294.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis. Gastroenterology. 2008 Dec; 135(6):1961-1971.e2.
Patton HM, Lavine JE, Van Natta ML, Schwimmer JB, Kleiner D, Molleston J, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 19013463; PMCID: PMC2628583.
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PubMed Mentions:
97 Fields:
Translation:
HumansCTClinical Trials
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Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study. Am J Gastroenterol. 2008 Sep; 103(9):2263-71.
Dunn W, Xu R, Wingard DL, Rogers C, Angulo P, Younossi ZM, Schwimmer JB. PMID: 18684196; PMCID: PMC2574666.
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PubMed Mentions:
131 Fields:
Translation:
Humans
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Fast break on the fat brake: mechanism of peroxisome proliferator-activated receptor-delta regulation of lipid accumulation in hepatocytes. Hepatology. 2008 Aug; 48(2):355-7.
Andrews DB, Schwimmer JB, Lavine JE. PMID: 18666254.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease. Circulation. 2008 Jul 15; 118(3):277-83.
Schwimmer JB, Pardee PE, Lavine JE, Blumkin AK, Cook S. PMID: 18591439; PMCID: PMC2996820.
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PubMed Mentions:
163 Fields:
Translation:
Humans
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Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology. 2008 Jun; 47(6):1947-54.
Dunn W, Xu R, Schwimmer JB. PMID: 18454505; PMCID: PMC6658188.
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PubMed Mentions:
70 Fields:
Translation:
Humans
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Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2008 Jul; 28(1):13-24.
Barshop NJ, Sirlin CB, Schwimmer JB, Lavine JE. PMID: 18397387.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Musculoskeletal pain in obese children and adolescents. Acta Paediatr. 2008 Apr; 97(4):489-93.
Stovitz SD, Pardee PE, Vazquez G, Duval S, Schwimmer JB. PMID: 18363957.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Relaxation effects in the quantification of fat using gradient echo imaging. Magn Reson Imaging. 2008 Apr; 26(3):347-59.
Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin CB. PMID: 18093781; PMCID: PMC2386876.
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PubMed Mentions:
222 Fields:
Translation:
Humans
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Pediatric obesity: the unique issues in Latino-American male youth. Am J Prev Med. 2008 Feb; 34(2):153-60.
Stovitz SD, Schwimmer JB, Martinez H, Story MT. PMID: 18201646.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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The obesity epidemic and nonalcoholic fatty liver disease in children. Curr Gastroenterol Rep. 2008 Feb; 10(1):67-72.
Dunn W, Schwimmer JB. PMID: 18417045.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Television viewing and hypertension in obese children. Am J Prev Med. 2007 Dec; 33(6):439-43.
Pardee PE, Norman GJ, Lustig RH, Preud'homme D, Schwimmer JB. PMID: 18022058.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Definitive diagnosis and assessment of risk for nonalcoholic fatty liver disease in children and adolescents. Semin Liver Dis. 2007 Aug; 27(3):312-8.
Schwimmer JB. PMID: 17682977.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Distinguishing eosinophilic esophagitis in pediatric patients: clinical, endoscopic, and histologic features of an emerging disorder. J Clin Gastroenterol. 2007 Mar; 41(3):252-6.
Aceves SS, Newbury RO, Dohil R, Schwimmer J, Bastian JF. PMID: 17426462.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Health-related quality of life in pediatric patients with irritable bowel syndrome: a comparative analysis. J Dev Behav Pediatr. 2006 Dec; 27(6):451-8.
Varni JW, Lane MM, Burwinkle TM, Fontaine EN, Youssef NN, Schwimmer JB, Pardee PE, Pohl JF, Easley DJ. PMID: 17164617.
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PubMed Mentions:
60 Fields:
Translation:
Humans
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Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):413-27.
Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE. PMID: 17033514.
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PubMed Mentions:
69 Fields:
Translation:
HumansPHPublic Health
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Prevalence of fatty liver in children and adolescents. Pediatrics. 2006 Oct; 118(4):1388-93.
Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. PMID: 17015527.
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PubMed Mentions:
546 Fields:
Translation:
Humans
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Clinical Research Network launches TONIC trial for treatment of nonalcoholic fatty liver disease in children. J Pediatr Gastroenterol Nutr. 2006 Feb; 42(2):129-30.
Lavine JE, Schwimmer JB. PMID: 16456401.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005 Sep; 42(3):641-9.
Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, Lavine JE. PMID: 16116629.
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PubMed Mentions:
251 Fields:
Translation:
Humans
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Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. J Pediatr Gastroenterol Nutr. 2005 Jul; 41(1):16-22.
Xanthakos SA, Schwimmer JB, Melin-Aldana H, Rothenberg ME, Witte DP, Cohen MB. PMID: 15990624.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents. Pediatrics. 2005 May; 115(5):e561-5.
Schwimmer JB, McGreal N, Deutsch R, Finegold MJ, Lavine JE. PMID: 15867021.
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PubMed Mentions:
137 Fields:
Translation:
Humans
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A phase 2 clinical trial of metformin as a treatment for non-diabetic paediatric non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2005 Apr 01; 21(7):871-9.
Schwimmer JB, Middleton MS, Deutsch R, Lavine JE. PMID: 15801922.
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PubMed Mentions:
65 Fields:
Translation:
HumansCTClinical Trials
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Abnormal aminotransferase activity in women with polycystic ovary syndrome. Fertil Steril. 2005 Feb; 83(2):494-7.
Schwimmer JB, Khorram O, Chiu V, Schwimmer WB. PMID: 15705403.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Nonalcoholic fatty liver disease in the pediatric population. Clin Liver Dis. 2004 Aug; 8(3):549-58, viii-ix.
Lavine JE, Schwimmer JB. PMID: 15331063.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Managing overweight in older children and adolescents. Pediatr Ann. 2004 Jan; 33(1):39-44.
Schwimmer JB. PMID: 14981868.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. J Pediatr. 2003 Oct; 143(4):500-5.
Schwimmer JB, Deutsch R, Rauch JB, Behling C, Newbury R, Lavine JE. PMID: 14571229.
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PubMed Mentions:
133 Fields:
Translation:
Humans
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Lumen and the liver--together again in NASHville. J Pediatr Gastroenterol Nutr. 2003 Oct; 37(4):523-4.
Schwimmer JB, Lavine JE. PMID: 14579849.
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PubMed Mentions: Fields:
Translation:
Animals
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Health-related quality of life of severely obese children and adolescents. JAMA. 2003 Apr 09; 289(14):1813-9.
Schwimmer JB, Burwinkle TM, Varni JW. PMID: 12684360.
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PubMed Mentions:
418 Fields:
Translation:
Humans
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Glutamine promotes triglyceride absorption in a dose-dependent manner. Am J Physiol Gastrointest Liver Physiol. 2002 Feb; 282(2):G317-23.
Schwimmer JB, Ee L, Zheng S, Tso P. PMID: 11804853.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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A tabulated summary of the FDG PET literature. J Nucl Med. 2001 May; 42(5 Suppl):1S-93S.
Gambhir SS, Czernin J, Schwimmer J, Silverman DH, Coleman RE, Phelps ME. PMID: 11483694.
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PubMed Mentions:
252 Fields:
Translation:
Humans
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Decision analysis for the cost-effective management of recurrent colorectal cancer. Ann Surg. 2001 Mar; 233(3):310-9.
Park KC, Schwimmer J, Shepherd JE, Phelps ME, Czernin JR, Schiepers C, Gambhir SS. PMID: 11224617; PMCID: PMC1421245.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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A meta-analysis of the literature for whole-body FDG PET detection of recurrent colorectal cancer. J Nucl Med. 2000 Jul; 41(7):1177-89.
Huebner RH, Park KC, Shepherd JE, Schwimmer J, Czernin J, Phelps ME, Gambhir SS. PMID: 10914907.
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PubMed Mentions:
79 Fields:
Translation:
Humans
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Transmission, natural history, and treatment of hepatitis C virus infection in the pediatric population. Semin Liver Dis. 2000; 20(1):37-46.
Schwimmer JB, Balistreri WF. PMID: 10895430.
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PubMed Mentions:
13 Fields:
Translation:
HumansPHPublic Health