Maria Marchetto

Title(s)Assistant Professor, Anthropology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Transcriptional signature profiling of IGF1-treated neural cells from idiopathic autistic patients
    NIH R03MH115426Jun 15, 2018 - Jun 30, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. NGLY1 mutations cause protein aggregation in human neurons. Cell Rep. 2023 12 26; 42(12):113466. Manole A, Wong T, Rhee A, Novak S, Chin SM, Tsimring K, Paucar A, Williams A, Newmeyer TF, Schafer ST, Rosh I, Kaushik S, Hoffman R, Chen S, Wang G, Snyder M, Cuervo AM, Andrade L, Manor U, Lee K, Jones JR, Stern S, Marchetto MC, Gage FH. PMID: 38039131; PMCID: PMC10826878.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Network size affects the complexity of activity in human iPSC-derived neuronal populations. bioRxiv. 2023 Nov 02. Uzun YS, Santos R, Marchetto MC, Padmanabhan K. PMID: 37961249; PMCID: PMC10635014.
      View in: PubMed   Mentions:
    3. Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. Mol Psychiatry. 2023 Mar 29. Niemsiri V, Rosenthal SB, Nievergelt CM, Maihofer AX, Marchetto MC, Santos R, Shekhtman T, Alliey-Rodriguez N, Anand A, Balaraman Y, Berrettini WH, Bertram H, Burdick KE, Calabrese JR, Calkin CV, Conroy C, Coryell WH, DeModena A, Eyler LT, Feeder S, Fisher C, Frazier N, Frye MA, Gao K, Garnham J, Gershon ES, Goes FS, Goto T, Harrington GJ, Jakobsen P, Kamali M, Kelly M, Leckband SG, Lohoff FW, McCarthy MJ, McInnis MG, Craig D, Millett CE, Mondimore F, Morken G, Nurnberger JI, Donovan CO, Øedegaard KJ, Ryan K, Schinagle M, Shilling PD, Slaney C, Stapp EK, Stautland A, Tarwater B, Zandi PP, Alda M, Fisch KM, Gage FH, Kelsoe JR. PMID: 36991131.
      View in: PubMed   Mentions: 5     Fields:    
    4. Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. NPJ Parkinsons Dis. 2022 Oct 18; 8(1):134. van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, Winner B, Winkler J, Gage FH, Bardy C. PMID: 36258029; PMCID: PMC9579158.
      View in: PubMed   Mentions: 3  
    5. Human-specific regulation of neural maturation identified by cross-primate transcriptomics. Curr Biol. 2022 Nov 21; 32(22):4797-4807.e5. Linker SB, Narvaiza I, Hsu JY, Wang M, Qiu F, Mendes APD, Oefner R, Kottilil K, Sharma A, Randolph-Moore L, Mejia E, Santos R, Marchetto MC, Gage FH. PMID: 36228612.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    6. Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients. NPJ Parkinsons Dis. 2022 Aug 10; 8(1):103. Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, Qiu F, Schafer S, Mansour AA, Mangan KP, Stern T, Ofer P, Stern Y, Diniz Mendes AP, Djamus J, Moore LR, Nayak R, Laufer SH, Aicher A, Rhee A, Wong TL, Nguyen T, Linker SB, Winner B, Freitas BC, Jones E, Sagi I, Bardy C, Brice A, Winkler J, Marchetto MC, Gage FH. PMID: 35948563; PMCID: PMC9365794.
      View in: PubMed   Mentions: 8  
    7. Brain aging, Alzheimer's disease, and the role of stem cells in primate comparative studies. J Comp Neurol. 2022 12; 530(17):2940-2953. August I, Semendeferi K, Marchetto MC. PMID: 35929189.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Methods for culturing adult CNS neurons reveal a CNS conditioning effect. Cell Rep Methods. 2022 07 18; 2(7):100255. van Niekerk EA, Kawaguchi R, Marques de Freria C, Groeniger K, Marchetto MC, Dupraz S, Bradke F, Geschwind DH, Gage FH, Tuszynski MH. PMID: 35880023; PMCID: PMC9308166.
      View in: PubMed   Mentions: 3  Translation:HumansCells
    9. Generation of inflammation-responsive astrocytes from glial progenitors derived from human pluripotent stem cells. STAR Protoc. 2022 06 17; 3(2):101261. Santos R, Mei A, Marchetto MC. PMID: 35313707; PMCID: PMC8933838.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Reaching into the toolbox: Stem cell models to study neuropsychiatric disorders. Stem Cell Reports. 2022 02 08; 17(2):187-210. Whiteley JT, Fernandes S, Sharma A, Mendes APD, Racha V, Benassi SK, Marchetto MC. PMID: 35063127; PMCID: PMC8828548.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    11. Unraveling Human Brain Development and Evolution Using Organoid Models. Front Cell Dev Biol. 2021; 9:737429. Fernandes S, Klein D, Marchetto MC. PMID: 34692694; PMCID: PMC8529117.
      View in: PubMed   Mentions: 8  
    12. Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. Stem Cell Reports. 2021 04 13; 16(4):825-835. Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, Gage FH. PMID: 33667413; PMCID: PMC8072028.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    13. Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients. Mol Psychiatry. 2021 06; 26(6):2440-2456. Santos R, Linker SB, Stern S, Mendes APD, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Kim Y, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH. PMID: 33398088; PMCID: PMC9129103.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    14. Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis. Mol Psychiatry. 2021 07; 26(7):3558-3571. Figueiredo T, Mendes APD, Moreira DP, Goulart E, Oliveira D, Kobayashi GS, Stern S, Kok F, Marchetto MC, Santos R, Gage FH, Zatz M. PMID: 32839513.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism. Mol Autism. 2020 06 26; 11(1):55. Linker SB, Mendes APD, Marchetto MC. PMID: 32591005; PMCID: PMC7320548.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    16. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):10055-10066. Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MCN, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR, Gleeson JG. PMID: 32312822; PMCID: PMC7211998.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    17. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Cell Rep Med. 2020 04 21; 1(1):100002. Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming GL, Gage FH, Diamond DJ, Wussow F, Shi Y. PMID: 33205055; PMCID: PMC7659592.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    18. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4392-4399. Shen W, Wang QW, Liu YN, Marchetto MC, Linker S, Lu SY, Chen Y, Liu C, Guo C, Xing Z, Shi W, Kelsoe JR, Alda M, Wang H, Zhong Y, Sui SF, Zhao M, Yang Y, Mi S, Cao L, Gage FH, Yao J. PMID: 32041882; PMCID: PMC7049155.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    19. A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients. Biol Psychiatry. 2020 07 15; 88(2):150-158. Stern S, Sarkar A, Galor D, Stern T, Mei A, Stern Y, Mendes APD, Randolph-Moore L, Rouleau G, Bang AG, Santos R, Alda M, Marchetto MC, Gage FH. PMID: 32278494; PMCID: PMC10871148.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    20. Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability. Cell Stem Cell. 2020 02 06; 26(2):221-233.e6. Wang M, Wei PC, Lim CK, Gallina IS, Marshall S, Marchetto MC, Alt FW, Gage FH. PMID: 32004479; PMCID: PMC7175642.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    21. Modeling Inflammation on Neurodevelopmental Disorders Using Pluripotent Stem Cells. Adv Neurobiol. 2020; 25:207-218. Freitas BC, Beltrão-Braga PCB, Marchetto MC. PMID: 32578148.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder. Biol Psychiatry. 2020 07 15; 88(2):139-149. Stern S, Sarkar A, Stern T, Mei A, Mendes APD, Stern Y, Goldberg G, Galor D, Nguyen T, Randolph-Moore L, Kim Y, Rouleau G, Bang A, Alda M, Santos R, Marchetto MC, Gage FH. PMID: 31732108; PMCID: PMC7108962.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    23. Dynamical Electrical Complexity Is Reduced during Neuronal Differentiation in Autism Spectrum Disorder. Stem Cell Reports. 2019 09 10; 13(3):474-484. Amatya DN, Linker SB, Mendes APD, Santos R, Erikson G, Shokhirev MN, Zhou Y, Sharpee T, Gage FH, Marchetto MC, Kim Y. PMID: 31474529; PMCID: PMC6739708.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack KNa Currents. J Neurosci. 2019 09 11; 39(37):7438-7449. Quraishi IH, Stern S, Mangan KP, Zhang Y, Ali SR, Mercier MR, Marchetto MC, McLachlan MJ, Jones EM, Gage FH, Kaczmarek LK. PMID: 31350261; PMCID: PMC6759030.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    25. Prediction of Response to Drug Therapy in Psychiatric Disorders. Focus (Am Psychiatr Publ). 2019 Jul; 17(3):294-307. Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. PMID: 32015721; PMCID: PMC6996058.
      View in: PubMed   Mentions: 3  
    26. Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons. Mol Psychiatry. 2019 06; 24(6):808-818. Vadodaria KC, Ji Y, Skime M, Paquola AC, Nelson T, Hall-Flavin D, Heard KJ, Fredlender C, Deng Y, Elkins J, Dani K, Le AT, Marchetto MC, Weinshilboum R, Gage FH. PMID: 30903001; PMCID: PMC7409972.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    27. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 2019 02 07; 8. Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH. PMID: 30730291; PMCID: PMC6366899.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    28. Mitochondria, Metabolism, and Redox Mechanisms in Psychiatric Disorders. Antioxid Redox Signal. 2019 08 01; 31(4):275-317. Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. PMID: 30585734; PMCID: PMC6602118.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    29. Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons. Mol Psychiatry. 2019 06; 24(6):795-807. Vadodaria KC, Ji Y, Skime M, Paquola A, Nelson T, Hall-Flavin D, Fredlender C, Heard KJ, Deng Y, Le AT, Dave S, Fung L, Li X, Marchetto MC, Weinshilboum R, Gage FH. PMID: 30700803.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    30. Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat Neurosci. 2019 02; 22(2):243-255. Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH. PMID: 30617258; PMCID: PMC6402576.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansCells
    31. Modeling Inflammation in Autism Spectrum Disorders Using Stem Cells. Front Pediatr. 2018; 6:394. Freitas BC, Mei A, Mendes APD, Beltrão-Braga PCB, Marchetto MC. PMID: 30619789; PMCID: PMC6299043.
      View in: PubMed   Mentions: 6  
    32. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell Stem Cell. 2018 05 03; 22(5):684-697.e9. Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH. PMID: 29727680; PMCID: PMC6345574.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    33. Prediction of response to drug therapy in psychiatric disorders. Open Biol. 2018 05; 8(5). Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. PMID: 29794033; PMCID: PMC5990649.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    34. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein. Mol Cell Neurosci. 2018 04; 88:222-230. Vofély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orbán TI, Sarkadi B, Homolya L, Marchetto MC, Réthelyi JM, Apáti Á. PMID: 29425968.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. Genome Med. 2018 01 04; 10(1):1. Vadodaria KC, Amatya DN, Marchetto MC, Gage FH. PMID: 29301565; PMCID: PMC5755287.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    36. Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons. Cell Tissue Res. 2018 01; 371(1):161-170. Vadodaria KC, Stern S, Marchetto MC, Gage FH. PMID: 28812143.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    37. Examining non-LTR retrotransposons in the context of the evolving primate brain. BMC Biol. 2017 08 11; 15(1):68. Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH. PMID: 28800766; PMCID: PMC5554003.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    38. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5635-E5644. Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W. PMID: 28630288; PMCID: PMC5514719.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    39. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 06 06; 8(6):1757-1769. Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH. PMID: 28591655; PMCID: PMC5470172.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    40. Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2017 04 15; 31(8):845. Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 28512238; PMCID: PMC5435895.
      View in: PubMed   Mentions:    Fields:    
    41. Conserved expression of transposon-derived non-coding transcripts in primate stem cells. BMC Genomics. 2017 02 28; 18(1):214. Ramsay L, Marchetto MC, Caron M, Chen SH, Busche S, Kwan T, Pastinen T, Gage FH, Bourque G. PMID: 28245871; PMCID: PMC5331655.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Mol Psychiatry. 2018 06; 23(6):1453-1465. Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. PMID: 28242870; PMCID: PMC5573640.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    43. Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges. Front Cell Neurosci. 2017; 11:30. Kim Y, Santos R, Gage FH, Marchetto MC. PMID: 28261061; PMCID: PMC5306135.
      View in: PubMed   Mentions: 30  
    44. Generating human serotonergic neurons in vitro: Methodological advances. Bioessays. 2016 11; 38(11):1123-1129. Vadodaria KC, Marchetto MC, Mertens J, Gage FH. PMID: 27716980.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    45. A human neurodevelopmental model for Williams syndrome. Nature. 2016 08 18; 536(7616):338-43. Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR. PMID: 27509850; PMCID: PMC4995142.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    46. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. 2016 08 11; 536(7615):205-9. Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, Denman L, Harshman L, Baker C, Raja A, Penewit K, Janke N, Tang WJ, Ventura M, Banci L, Antonacci F, Akey JM, Amemiya CT, Gage FH, Reymond A, Eichler EE. PMID: 27487209; PMCID: PMC4988886.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    47. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry. 2017 06; 22(6):820-835. Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR. PMID: 27378147; PMCID: PMC5215991.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansCells
    48. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience. Nat Rev Neurosci. 2016 07; 17(7):424-37. Mertens J, Marchetto MC, Bardy C, Gage FH. PMID: 27194476; PMCID: PMC6276815.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    49. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2016 05 15; 30(10):1155-71. Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 27198230; PMCID: PMC4888837.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    50. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 2016 Apr 07; 18(4):467-80. Otani T, Marchetto MC, Gage FH, Simons BD, Livesey FJ. PMID: 27049876; PMCID: PMC4826446.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    51. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):751-6. Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. PMID: 26733678; PMCID: PMC4725523.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    52. The different moods of human serotonergic neurons. Mol Psychiatry. 2016 Jan; 21(1):3. Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. PMID: 26678308.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    53. Synaptic activity: An emerging player in schizophrenia. Brain Res. 2017 02 01; 1656:68-75. Sarkar A, Marchetto MC, Gage FH. PMID: 26723567.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    54. Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2016 Feb 11; 530(7589):242. Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Oedegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM, Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. PMID: 26605530.
      View in: PubMed   Mentions: 3     Fields:    
    55. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. 2015 Dec 08; 5(6):933-945. Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. PMID: 26610635; PMCID: PMC4881284.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    56. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2015 Nov 05; 527(7576):95-9. Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Alba M, Nievergelt CM, Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. PMID: 26524527; PMCID: PMC4742055.
      View in: PubMed   Mentions: 251     Fields:    Translation:HumansCells
    57. Generation of functional human serotonergic neurons from fibroblasts. Mol Psychiatry. 2016 Jan; 21(1):49-61. Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. PMID: 26503761.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    58. Primate-specific ORF0 contributes to retrotransposon-mediated diversity. Cell. 2015 Oct 22; 163(3):583-93. Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. PMID: 26496605.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    59. Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest. Cell. 2015 Sep 24; 163(1):68-83. Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J. PMID: 26365491; PMCID: PMC4848043.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    60. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry. 2015 Nov; 20(11):1350-65. Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. PMID: 25385366; PMCID: PMC4427554.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    61. Mobile DNA elements in the generation of diversity and complexity in the brain. Nat Rev Neurosci. 2014 Aug; 15(8):497-506. Erwin JA, Marchetto MC, Gage FH. PMID: 25005482; PMCID: PMC4443810.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansCells
    62. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 2014 Jul 02; 83(1):69-86. Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. PMID: 24991955; PMCID: PMC4277209.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    63. How to make a hippocampal dentate gyrus granule neuron. Development. 2014 Jun; 141(12):2366-75. Yu DX, Marchetto MC, Gage FH. PMID: 24917496.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    64. Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. Hum Mol Genet. 2014 Sep 15; 23(R1):R27-34. Winner B, Marchetto MC, Winkler J, Gage FH. PMID: 24821704.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    65. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. 2014 Mar 11; 2(3):295-310. Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH. PMID: 24672753; PMCID: PMC3964286.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansCells
    66. Your brain under the microscope: the promise of stem cells. Cerebrum. 2014 Jan; 2014:1. Marchetto MC, Gage FH. PMID: 25009691; PMCID: PMC4087191.
      View in: PubMed   Mentions: 5  
    67. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. Hum Mol Genet. 2014 May 15; 23(10):2527-41. Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B. PMID: 24381312; PMCID: PMC3990156.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    68. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 2013 Nov 28; 503(7477):525-529. Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. PMID: 24153179; PMCID: PMC4064720.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    69. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Biol Psychiatry. 2014 Jun 15; 75(12):929-35. Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR. PMID: 24041506.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    70. Therapeutic translation of iPSCs for treating neurological disease. Cell Stem Cell. 2013 Jun 06; 12(6):678-88. Yu DX, Marchetto MC, Gage FH. PMID: 23746977.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    71. Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Sci Transl Med. 2013 Jun 05; 5(188):188lr2. Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. PMID: 23740898.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    72. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Res. 2013 Sep; 11(2):743-57. Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. PMID: 23759711; PMCID: PMC3979966.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    73. Dynamic association of NUP98 with the human genome. PLoS Genet. 2013; 9(2):e1003308. Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer MW. PMID: 23468646; PMCID: PMC3585015.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    74. Induced pluripotent stem cells: the new patient? Nat Rev Mol Cell Biol. 2012 Nov; 13(11):713-26. Bellin M, Marchetto MC, Gage FH, Mummery CL. PMID: 23034453.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansAnimalsCells
    75. Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med. 2012 Aug 01; 4(145):145ra104. Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. PMID: 22855461.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansCells
    76. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12556-61. Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC. PMID: 22814375; PMCID: PMC3412010.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    77. Modeling brain disease in a dish: really? Cell Stem Cell. 2012 Jun 14; 10(6):642-645. Marchetto MC, Gage FH. PMID: 22704498.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    78. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20382-7. Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. PMID: 22159035; PMCID: PMC3251057.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    79. Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises. Hum Mol Genet. 2011 Oct 15; 20(R2):R109-15. Marchetto MC, Brennand KJ, Boyer LF, Gage FH. PMID: 21828073; PMCID: PMC4447776.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    80. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum Mol Genet. 2011 Sep 15; 20(18):3642-52. Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M. PMID: 21685205; PMCID: PMC3159551.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    81. L1 retrotransposition in neurons is modulated by MeCP2. Nature. 2010 Nov 18; 468(7322):443-6. Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH. PMID: 21085180; PMCID: PMC3059197.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansAnimalsCells
    82. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 2010 Nov 12; 143(4):527-39. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. PMID: 21074045; PMCID: PMC3003590.
      View in: PubMed   Mentions: 665     Fields:    Translation:HumansCells
    83. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci. 2010 Nov; 13(11):1338-44. Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. PMID: 20975758; PMCID: PMC3324277.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    84. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends Neurosci. 2010 Aug; 33(8):345-54. Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH. PMID: 20471112; PMCID: PMC2916067.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    85. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum Mol Genet. 2010 Apr 15; 19(R1):R71-6. Marchetto MC, Winner B, Gage FH. PMID: 20418487; PMCID: PMC2875052.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    86. Mechanisms underlying inflammation in neurodegeneration. Cell. 2010 Mar 19; 140(6):918-34. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. PMID: 20303880; PMCID: PMC2873093.
      View in: PubMed   Mentions: 1493     Fields:    Translation:HumansAnimals
    87. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus. 2009 Oct; 19(10):1002-7. Muotri AR, Zhao C, Marchetto MC, Gage FH. PMID: 19771587; PMCID: PMC2758700.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    88. Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One. 2009 Sep 18; 4(9):e7076. Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. PMID: 19763270; PMCID: PMC2741600.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansAnimalsCells
    89. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 2008 Dec 04; 3(6):649-57. Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH. PMID: 19041781.
      View in: PubMed   Mentions: 247     Fields:    Translation:HumansAnimalsCells
    90. Identification of XP complementation groups by recombinant adenovirus carrying DNA repair genes. J Invest Dermatol. 2009 Feb; 129(2):502-6. Leite RA, Marchetto MC, Muotri AR, Vasconcelos Dde M, de Oliveira ZN, Machado MC, Menck CF. PMID: 18685619.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    91. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Hum Mol Genet. 2008 Apr 15; 17(R1):R67-75. Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. PMID: 18632700.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    92. Exploring DNA damage responses in human cells with recombinant adenoviral vectors. Hum Exp Toxicol. 2007 Nov; 26(11):899-906. Armelini MG, Lima-Bessa KM, Marchetto MC, Muotri AR, Chiganças V, Leite RA, Carvalho H, Menck CF. PMID: 18042584.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    93. The necessary junk: new functions for transposable elements. Hum Mol Genet. 2007 Oct 15; 16 Spec No. 2:R159-67. Muotri AR, Marchetto MC, Coufal NG, Gage FH. PMID: 17911158.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    94. LINE-1 retrotransposition in human embryonic stem cells. Hum Mol Genet. 2007 Jul 01; 16(13):1569-77. Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. PMID: 17468180.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    95. Functional lentiviral vectors for xeroderma pigmentosum gene therapy. J Biotechnol. 2006 Dec 01; 126(4):424-30. Marchetto MC, Correa RG, Menck CF, Muotri AR. PMID: 16857285.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    96. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature. 2005 Jun 16; 435(7044):903-10. Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. PMID: 15959507.
      View in: PubMed   Mentions: 479     Fields:    Translation:HumansAnimalsCells
    97. Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus. Cancer Gene Ther. 2005 Apr; 12(4):389-96. Armelini MG, Muotri AR, Marchetto MC, de Lima-Bessa KM, Sarasin A, Menck CF. PMID: 15650764.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    98. Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17759-64. Marchetto MC, Muotri AR, Burns DK, Friedberg EC, Menck CF. PMID: 15598745; PMCID: PMC539722.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    99. Low amounts of the DNA repair XPA protein are sufficient to recover UV-resistance. Carcinogenesis. 2002 Jun; 23(6):1039-46. Muotri AR, Marchetto MC, Suzuki MF, Okazaki K, Lotfi CF, Brumatti G, Amarante-Mendes GP, Menck CF. PMID: 12082027.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    100. An adenovirus vector containing the suicide gene thymidine kinase for a broad application in cancer gene therapy. Mem Inst Oswaldo Cruz. 2002 Jun; 97(4):547-52. Magalhaes GS, Muotri AR, Marchetto MC, Menck CF, Ventura AM. PMID: 12118289.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
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