BiographyDr. Kremen received his Ph.D. in Clinical Psychology from Boston University in 1990. He was faculty member at Harvard Medical School and UC Davis before joining the faculty at UCSD in 2003. He is Director of the Twin Research Laboratory in the Department’s Center for Behavioral Genomic, a faculty member of the Stein Institute for Research on Aging and the San Diego State/UCSD Joint Doctoral Program in Clinical Psychology, and a scientific member of the VA San Diego Center of Excellence for Stress and Mental Health (CESAMH). He oversees the Vietnam Era Twin Study of Aging (VETSA) projects, wave 1 of which is a publicly available research resource consisting of neuropsychological, biomedical, and neuroimaging data.
Research InterestsDr. Kremen’s primary current research focus is on behavioral genetic/twin studies of cognition and aging. He has led the Vietnam Era Twin Study of Aging (VETSA) projects since 2003. Wave 3 of the longitudinal VETSA project begins in 2015. There are two major goals of these projects: 1) early identification of risk for mild cognitive impairment (MCI) and Alzheimer’s disease, including the search for novel biomarkers; and 2) elucidating the heterogeneity of aging trajectories. This work involves examination of genetic and environmental influences on the interplay among cognitive, brain, biomedical, and psychosocial factors. Genome-wide genotyping and epigenetics are also integrated into traditional twin designs. Twin studies also make it possible to conduct cotwin-control designs, which provide an ideal case-control study.
Dr. Kremen’s other research interest is behavioral genetic studies of psychiatric disorders, primarily posttraumatic stress disorder (PTSD) and schizophrenia. As part of the CESAMH, he studies outcomes of PTSD over periods of 30-40 years from a behavior genetics perspective. He also collaborates on studies of gene expression in PTSD and schizophrenia.