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Jerrold Olefsky

Title(s)Professor, Medicine
SchoolHealth Sciences
Phone858-534-6651
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    Collapse Research 
    Collapse Research Activities and Funding
    Effects of Fractalkine on Beta Cell Function
    NIH/NIDDK R01DK101395Sep 19, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Energetics &Breast Cancer: Obesity, Inflammation, Insulin Resistance &Risk
    NIH/NCI U54CA155435Jul 7, 2011 - May 31, 2016
    Role: Co-Investigator
    Molecular Mechanisms of Inflammation, Steatosis and Hepatic Insulin Resistance
    NIH/NIDDK R24DK090962Sep 30, 2010 - Aug 31, 2012
    Role: Principal Investigator
    Gene Networks controlling macrophage-adipocyte interactions in insulin
    NIH/NIDDK P01DK074868Apr 1, 2006 - Apr 30, 2017
    Role: Co-Investigator
    Estrogen Effects in Insulin Target and Granulosa Cells
    NIH/NIDDK R55DK068606Sep 30, 2004 - Aug 31, 2006
    Role: Principal Investigator
    Diabetes Research Center (DRC)
    NIH/NIDDK P30DK063491Dec 1, 2002 - Jun 30, 2020
    Role: Principal Investigator
    Estrogens and Insulin Resistance in Women
    NIH/NIDDK R01DK061964Jul 1, 2002 - May 31, 2007
    Role: Principal Investigator
    PKA & PKC Targeting Mechanisms (Program Project)
    NIH/NIDDK P01DK054441Dec 15, 1998 - Mar 31, 2018
    Role: Co-Investigator
    Diabetes Prevention Program Outcomes Study (DPPOS) Phase 3 ? Research Project
    NIH/NIDDK U01DK048339Sep 10, 1994 - Jan 31, 2021
    Role: Principal Investigator
    Training Program in Diabetes Research
    NIH/NIDDK T32DK007494Jul 1, 1984 - Aug 31, 2022
    Role: Principal Investigator
    TRAINING PROGRAM IN DIABETES RESEARCH
    NIH/NIADDK T32AM007494Jul 1, 1984 - Jun 30, 1989
    Role: Principal Investigator
    Insulin Receptors and the Glucose Transport System
    NIH/NIDDK R01DK033651Aug 1, 1983 - Jun 30, 2014
    Role: Principal Investigator
    INSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEM
    NIH/NIDDK R37DK033651Aug 1, 1983 - Jun 30, 2010
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH/NIDDK R01DK033649Aug 1, 1983 - Mar 31, 2002
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH/NIDDK R37DK033649Aug 1, 1983 - Mar 31, 1998
    Role: Principal Investigator
    INSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEM
    NIH/NIADDK R01AM033651Aug 1, 1983 - Mar 31, 1990
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH/NIADDK R01AM033649Aug 1, 1983 - May 31, 1989
    Role: Principal Investigator
    Center for Reproductive Science and Medicine
    NIH/NICHD U54HD012303Dec 1, 1978 - Mar 31, 2014
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, Jain M, Olefsky JM. Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance. Diabetes. 2019 Jul; 68(7):1415-1426. PMID: 31010956.
      View in: PubMed
    2. Liang P, Henning SM, Guan J, Grogan T, Elashoff D, Olefsky JM, Cohen P, Aronson WJ. Role of Host GPR120 in Mediating Dietary Omega-3 Fatty Acid Inhibition of Prostate Cancer. J Natl Cancer Inst. 2019 Jan 01; 111(1):52-59. PMID: 30202902.
      View in: PubMed
    3. Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting ß Cell Proliferation and Function in Obesity. Cell Metab. 2019 Feb 05; 29(2):457-474.e5. PMID: 30595478.
      View in: PubMed
    4. Rickert E, Fernandez MO, Choi I, Gorman M, Olefsky JM, Webster NJG. Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction. J Endocr Soc. 2019 Feb 01; 3(2):427-445. PMID: 30746504.
      View in: PubMed
    5. Riopel M, Vassallo M, Ehinger E, Pattison J, Bowden K, Winkels H, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Larson CJ, Ley K, Cabrales P, Witztum JL, Olefsky JM, Lee YS. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice. Mol Metab. 2019 Feb; 20:89-101. PMID: 30553772.
      View in: PubMed
    6. Seo JB, Riopel M, Cabrales P, Huh JY, Bandyopadhyay GK, Andreyev AY, Murphy AN, Beeman SC, Smith GI, Klein S, Lee YS, Olefsky JM. Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity. Nat Metab. 2019 Jan; 1(1):86-97. PMID: 31528845.
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    7. Hoveyda HR, Fraser GL, Zoute L, Dutheuil G, Schils D, Brantis C, Lapin A, Parcq J, Guitard S, Lenoir F, Bousmaqui ME, Rorive S, Hospied S, Blanc S, Bernard J, Ooms F, McNelis JC, Olefsky JM. N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model. Bioorg Med Chem. 2018 10 01; 26(18):5169-5180. PMID: 30253886.
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    8. Korman B, Marangoni RG, Lord G, Olefsky J, Tourtellotte W, Varga J. Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis. Arthritis Res Ther. 2018 07 11; 20(1):145. PMID: 29996896.
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    9. Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, Saltiel AR. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7819-7824. PMID: 29915037.
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    10. Riopel M, Seo JB, Bandyopadhyay GK, Li P, Wollam J, Chung H, Jung SR, Murphy A, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Koh DS, Larson CJ, Olefsky JM, Lee YS. Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function. J Clin Invest. 2018 04 02; 128(4):1458-1470. PMID: 29504946.
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    11. Lee YS, Wollam J, Olefsky JM. An Integrated View of Immunometabolism. Cell. 2018 01 11; 172(1-2):22-40. PMID: 29328913.
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    12. Ying W, Riopel M, Bandyopadhyay G, Dong Y, Birmingham A, Seo JB, Ofrecio JM, Wollam J, Hernandez-Carretero A, Fu W, Li P, Olefsky JM. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. Cell. 2017 Oct 05; 171(2):372-384.e12. PMID: 28942920.
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    13. Ying W, Wollam J, Ofrecio JM, Bandyopadhyay G, El Ouarrat D, Lee YS, Oh DY, Li P, Osborn O, Olefsky JM. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. J Clin Invest. 2017 Mar 01; 127(3):1019-1030. PMID: 28192375.
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    14. Saltiel AR, Olefsky JM. Inflammatory mechanisms linking obesity and metabolic disease. J Clin Invest. 2017 01 03; 127(1):1-4. PMID: 28045402.
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    15. Fernandez MO, Sharma S, Kim S, Rickert E, Hsueh K, Hwang V, Olefsky JM, Webster NJ. Obese Neuronal PPAR? Knockout Mice Are Leptin Sensitive but Show Impaired Glucose Tolerance and Fertility. Endocrinology. 2017 01 01; 158(1):121-133. PMID: 27841948.
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    16. Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AMF, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, Ying W, Osborn O, Wollam J, Brenner M, Olefsky JM. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance. Cell. 2016 11 03; 167(4):973-984.e12. PMID: 27814523.
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    17. Oh DY, Olefsky JM. G protein-coupled receptors as targets for anti-diabetic therapeutics. Nat Rev Drug Discov. 2016 03; 15(3):161-72. PMID: 26822831.
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    18. Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, Olefsky JM, Akassoglou K. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Rep. 2016 Jan 12; 14(2):255-68. PMID: 26748707.
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    19. Lackey DE, Olefsky JM. Regulation of metabolism by the innate immune system. Nat Rev Endocrinol. 2016 Jan; 12(1):15-28. PMID: 26553134.
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    20. Kesby JP, Kim JJ, Scadeng M, Woods G, Kado DM, Olefsky JM, Jeste DV, Achim CL, Semenova S. Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet. PLoS One. 2015; 10(10):e0140034. PMID: 26448649.
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    21. McNelis JC, Lee YS, Mayoral R, van der Kant R, Johnson AM, Wollam J, Olefsky JM. GPR43 Potentiates ß-Cell Function in Obesity. Diabetes. 2015 Sep; 64(9):3203-17. PMID: 26023106.
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    22. Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS One. 2015; 10(4):e0122195. PMID: 25837594.
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    23. Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM. Adipocyte SIRT1 knockout promotes PPAR? activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Mol Metab. 2015 May; 4(5):378-91. PMID: 25973386.
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    24. Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 2015 Apr 16; 520(7547):388. PMID: 25739500.
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    25. Li P, Oh DY, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nat Med. 2015 Mar; 21(3):239-247. PMID: 25706874.
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    26. Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med. 2015 Feb; 21(2):159-65. PMID: 25559344.
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    27. Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh DY. Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. Diabetes. 2015 Apr; 64(4):1120-30. PMID: 25315009.
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    28. Chung H, Lee YS, Mayoral R, Oh DY, Siu JT, Webster NJ, Sears DD, Olefsky JM, Ellies LG. Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer. Oncogene. 2015 Jul; 34(27):3504-13. PMID: 25220417.
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    29. McNelis JC, Olefsky JM. Macrophages, immunity, and metabolic disease. Immunity. 2014 Jul 17; 41(1):36-48. PMID: 25035952.
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    30. Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 2014 Sep 18; 513(7518):436-9. PMID: 25043058.
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    31. Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nat Med. 2014 Aug; 20(8):942-7. PMID: 24997608.
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    32. Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest. 2014 Aug; 124(8):3566-78. PMID: 24983318.
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    33. Lee YS, Kim JW, Osborne O, Oh DY, Sasik R, Schenk S, Chen A, Chung H, Murphy A, Watkins SM, Quehenberger O, Johnson RS, Olefsky JM. Increased adipocyte O2 consumption triggers HIF-1a, causing inflammation and insulin resistance in obesity. Cell. 2014 Jun 05; 157(6):1339-52. PMID: 24906151.
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    34. Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. C/EBPa regulates macrophage activation and systemic metabolism. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1144-54. PMID: 24691027.
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    35. Fink LN, Costford SR, Lee YS, Jensen TE, Bilan PJ, Oberbach A, Blüher M, Olefsky JM, Sams A, Klip A. Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans. Obesity (Silver Spring). 2014 Mar; 22(3):747-57. PMID: 24030890.
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    36. Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 2013 Sep 26; 155(1):200-214. PMID: 24074869.
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    37. Ravnskjaer K, Hogan MF, Lackey D, Tora L, Dent SY, Olefsky J, Montminy M. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013 Oct; 123(10):4318-28. PMID: 24051374.
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    38. Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS. Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Mol Cell Proteomics. 2013 Dec; 12(12):3744-58. PMID: 24030101.
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    39. Lee YS, Morinaga H, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky J. The fractalkine/CX3CR1 system regulates ß cell function and insulin secretion. Cell. 2013 Apr 11; 153(2):413-25. PMID: 23582329.
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    40. Sharma S, Morinaga H, Hwang V, Fan W, Fernandez MO, Varki N, Olefsky JM, Webster NJ. Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LßT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice. Endocrinology. 2013 Jun; 154(6):2188-99. PMID: 23525221.
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    41. Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. J Biol Chem. 2013 Apr 12; 288(15):10722-35. PMID: 23457303.
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    42. Johnson AM, Olefsky JM. The origins and drivers of insulin resistance. Cell. 2013 Feb 14; 152(4):673-84. PMID: 23415219.
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    43. Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, Li P, Olefsky JM, Saltiel AR. An inhibitor of the protein kinases TBK1 and IKK-? improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar; 19(3):313-21. PMID: 23396211.
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    44. Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes Control. 2013 Apr; 24(4):695-704. PMID: 23378138.
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    45. Jiao J, Bae EJ, Bandyopadhyay G, Oliver J, Marathe C, Chen M, Hsu JY, Chen Y, Tian H, Olefsky JM, Saberi M. Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa/fa rats. Diabetes. 2013 Apr; 62(4):1074-83. PMID: 23248171.
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    46. Qatanani M, Tan Y, Dobrin R, Greenawalt DM, Hu G, Zhao W, Olefsky JM, Sears DD, Kaplan LM, Kemp DM. Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients. Diabetes. 2013 Mar; 62(3):855-63. PMID: 23223024.
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    47. Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metab. 2012 Sep 05; 16(3):311-21. PMID: 22958918.
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    48. Talukdar S, Oh DY, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med. 2012 Sep; 18(9):1407-12. PMID: 22863787.
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    49. Heinrichsdorff J, Olefsky JM. Fetuin-A: the missing link in lipid-induced inflammation. Nat Med. 2012 Aug; 18(8):1182-3. PMID: 22869185.
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    50. Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Lazarowski E, Olefsky JM, Kim JJ. GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity. J Immunol. 2012 Aug 15; 189(4):1992-9. PMID: 22778393.
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    51. Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. J Clin Invest. 2012 Jul; 122(7):2444-53. PMID: 22653059.
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    52. Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. A PPAR?-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature. 2012 May 17; 485(7398):391-4. PMID: 22522926.
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    53. Oh DY, Olefsky JM. Omega 3 fatty acids and GPR120. Cell Metab. 2012 May 02; 15(5):564-5. PMID: 22560206.
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    54. Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 2012 May 02; 15(5):635-45. PMID: 22560216.
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    55. Kim JJ, Fan W, Olefsky JM. Putting the brakes on FOXO1 in fat. EMBO J. 2012 May 16; 31(10):2240-1. PMID: 22510885.
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    56. Bae EJ, Xu J, Oh DY, Bandyopadhyay G, Lagakos WS, Keshwani M, Olefsky JM. Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance. J Biol Chem. 2012 May 25; 287(22):18769-80. PMID: 22493495.
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    57. Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15):5838-43. PMID: 22460790.
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    58. Osborn O, Olefsky JM. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med. 2012 Mar 06; 18(3):363-74. PMID: 22395709.
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    59. Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. Increased macrophage migration into adipose tissue in obese mice. Diabetes. 2012 Feb; 61(2):346-54. PMID: 22190646.
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    60. Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI. SirT1 regulates adipose tissue inflammation. Diabetes. 2011 Dec; 60(12):3235-45. PMID: 22110092.
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    61. Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM. Adipocyte NCoR knockout decreases PPAR? phosphorylation and enhances PPAR? activity and insulin sensitivity. Cell. 2011 Nov 11; 147(4):815-26. PMID: 22078880.
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    62. Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest. 2011 Nov; 121(11):4281-8. PMID: 21985785.
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    63. Lee YS, Li P, Huh JY, Hwang IJ, Lu M, Kim JI, Ham M, Talukdar S, Chen A, Lu WJ, Bandyopadhyay GK, Schwendener R, Olefsky J, Kim JB. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes. 2011 Oct; 60(10):2474-83. PMID: 21911747.
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    64. Ohtsubo K, Chen MZ, Olefsky JM, Marth JD. Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport. Nat Med. 2011 Aug 14; 17(9):1067-75. PMID: 21841783.
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    65. Talukdar S, Olefsky JM, Osborn O. Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases. Trends Pharmacol Sci. 2011 Sep; 32(9):543-50. PMID: 21663979.
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    66. Lan D, Lu M, Sharma S, Mellon PL, Olefsky JM, Webster NJ. Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHß gene expression by a SirT1-independent pathway in LßT2 gonadotrope cells. Reprod Toxicol. 2011 Jul; 32(1):85-92. PMID: 21679764.
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    67. Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. Brain PPAR-? promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med. 2011 May; 17(5):618-22. PMID: 21532596.
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    200. Nakashima N, Rose DW, Xiao S, Egawa K, Martin SS, Haruta T, Saltiel AR, Olefsky JM. The functional role of CrkII in actin cytoskeleton organization and mitogenesis. J Biol Chem. 1999 Jan 29; 274(5):3001-8. PMID: 9915838.
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    222. Thomaseth K, Pacini G, Clodi M, Kautzky-Willer A, Nolan JJ, Prager R, Olefsky JM, Ludvik B. Amylin release during oral glucose tolerance test. Diabet Med. 1997 Jun; 14 Suppl 2:S29-34. PMID: 9212327.
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    257. Olefsky JM, Nolan JJ. Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms. Am J Clin Nutr. 1995 04; 61(4 Suppl):980S-986S. PMID: 7900697.
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    258. Pillay TS, Sasaoka T, Olefsky JM. Insulin stimulates the tyrosine dephosphorylation of pp125 focal adhesion kinase. J Biol Chem. 1995 Jan 20; 270(3):991-4. PMID: 7836419.
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    259. Pillay TS, Langlois WJ, Olefsky JM. The genetics of non-insulin-dependent diabetes mellitus. Adv Genet. 1995; 32:51-98. PMID: 7741025.
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    260. Sasaoka T, Langlois WJ, Leitner JW, Draznin B, Olefsky JM. The signaling pathway coupling epidermal growth factor receptors to activation of p21ras. J Biol Chem. 1994 Dec 23; 269(51):32621-5. PMID: 7798267.
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    261. Lee MK, Miles PD, Khoursheed M, Gao KM, Moossa AR, Olefsky JM. Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes. 1994 Dec; 43(12):1435-9. PMID: 7958495.
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    262. Langlois WJ, Medh J, Leitner JW, Sasaoka T, Olefsky JM, Draznin B. Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. Endocrinology. 1994 Dec; 135(6):2412-7. PMID: 7988425.
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    263. Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL. Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP. J Biol Chem. 1994 Nov 04; 269(44):27186-92. PMID: 7525547.
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    264. Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med. 1994 Nov 03; 331(18):1188-93. PMID: 7935656.
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    265. Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM. Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol Cell Biol. 1994 Nov; 14(11):7466-75. PMID: 7935461.
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    266. Miles PD, Deftos LJ, Moossa AR, Olefsky JM. Islet amyloid polypeptide (amylin) increases the renal excretion of calcium in the conscious dog. Calcif Tissue Int. 1994 Oct; 55(4):269-73. PMID: 7820778.
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    267. Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke TR, Roller PP, Shoelson SE, Olefsky JM. Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J Biol Chem. 1994 Aug 19; 269(33):21244-8. PMID: 8063747.
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    268. Zapf A, Hsu D, Olefsky JM. Comparison of the intracellular itineraries of insulin-like growth factor-I and insulin and their receptors in Rat-1 fibroblasts. Endocrinology. 1994 Jun; 134(6):2445-52. PMID: 8194471.
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    269. Grako KA, McClain DA, Olefsky JM. Hybrid formation between endogenous mouse and transfected human tyrosine kinase-deficient (A/K1018) insulin receptors leads to decreased insulin sensitivity in 3T3-L1 adipocytes. Mol Endocrinol. 1994 Jun; 8(6):682-92. PMID: 7935484.
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    270. Sasaoka T, Rose DW, Jhun BH, Saltiel AR, Draznin B, Olefsky JM. Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J Biol Chem. 1994 May 06; 269(18):13689-94. PMID: 7513704.
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    271. Pang L, Milarski KL, Ohmichi M, Takata Y, Olefsky JM, Saltiel AR. Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase. J Biol Chem. 1994 Apr 08; 269(14):10604-8. PMID: 8144649.
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    272. Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J Biol Chem. 1994 Apr 08; 269(14):10734-8. PMID: 8144662.
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    273. Ugi S, Maegawa H, Olefsky JM, Shigeta Y, Kashiwagi A. Src homology 2 domains of protein tyrosine phosphatase are associated in vitro with both the insulin receptor and insulin receptor substrate-1 via different phosphotyrosine motifs. FEBS Lett. 1994 Mar 07; 340(3):216-20. PMID: 7510639.
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    274. Jhun BH, Meinkoth JL, Leitner JW, Draznin B, Olefsky JM. Insulin and insulin-like growth factor-I signal transduction requires p21ras. J Biol Chem. 1994 Feb 25; 269(8):5699-704. PMID: 8119907.
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    275. Ciaraldi TP, Kettel M, el-Roeiy A, Madar Z, Reichart D, Yen SS, Olefsky JM. Mechanisms of cellular insulin resistance in human pregnancy. Am J Obstet Gynecol. 1994 Feb; 170(2):635-41. PMID: 8116725.
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    276. Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM. Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity. J Clin Endocrinol Metab. 1994 Feb; 78(2):471-7. PMID: 8106637.
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    277. Hsu D, Knudson PE, Zapf A, Rolband GC, Olefsky JM. NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling. Endocrinology. 1994 Feb; 134(2):744-50. PMID: 8299569.
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    278. Rose DW, Saltiel AR, Majumdar M, Decker SJ, Olefsky JM. Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):797-801. PMID: 8290602.
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    279. Freidenberg GR, Suter S, Henry RR, Nolan J, Reichart D, Olefsky JM. Delayed onset of insulin activation of the insulin receptor kinase in vivo in human skeletal muscle. Diabetes. 1994 Jan; 43(1):118-26. PMID: 8262308.
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    280. Rolband GC, Williams JF, Webster NJ, Hsu D, Olefsky JM. Deletion of exon 21 of the insulin receptor eliminates tyrosine kinase activity but preserves mitogenic signaling. Biochemistry. 1993 Dec 14; 32(49):13545-50. PMID: 8257690.
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    281. Kenner KA, Hill DE, Olefsky JM, Kusari J. Regulation of protein tyrosine phosphatases by insulin and insulin-like growth factor I. J Biol Chem. 1993 Dec 05; 268(34):25455-62. PMID: 8244979.
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    282. Karnieli E, Garvey WT, Olefsky JM, Hueckstead TP, Harel C, Maianu L, Armoni M. Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes. Endocrinology. 1993 Dec; 133(6):2943-50. PMID: 8243322.
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    283. Draznin B, Chang L, Leitner JW, Takata Y, Olefsky JM. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors. J Biol Chem. 1993 Sep 25; 268(27):19998-20001. PMID: 8376360.
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    284. Kaliman P, Baron V, Alengrin F, Takata Y, Webster NJ, Olefsky JM, Van Obberghen E. The insulin receptor C-terminus is involved in regulation of the receptor kinase activity. Biochemistry. 1993 Sep 21; 32(37):9539-44. PMID: 7690586.
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    285. Hsu D, Olefsky JM. Effect of a major histocompatibility complex class I peptide on insulin-like growth factor-I receptor internalization and biological signaling. Endocrinology. 1993 Sep; 133(3):1247-51. PMID: 8365366.
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    286. Rolband GC, Williams JF, Webster NJ, Olefsky JM. Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling. Endocrinology. 1993 Sep; 133(3):1437-43. PMID: 8396020.
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    287. Pilch PF, Wilkinson W, Garvey WT, Ciaraldi TP, Hueckstaedt TP, Olefsky JM. Insulin-responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles. J Clin Endocrinol Metab. 1993 Jul; 77(1):286-9. PMID: 8325954.
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    288. Sasaoka T, Takata Y, Kusari J, Anderson CM, Langlois WJ, Olefsky JM. Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4379-83. PMID: 8506276.
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    289. Anderson CM, Henry RR, Knudson PE, Olefsky JM, Webster NJ. Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects. J Clin Endocrinol Metab. 1993 May; 76(5):1380-2. PMID: 7684396.
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    290. Begum N, Olefsky JM, Draznin B. Mechanism of impaired metabolic signaling by a truncated human insulin receptor. Decreased activation of protein phosphatase 1 by insulin. J Biol Chem. 1993 Apr 15; 268(11):7917-22. PMID: 8385127.
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    291. Smith RM, Sasaoka T, Shah N, Takata Y, Kusari J, Olefsky JM, Jarett L. A truncated human insulin receptor missing the COOH-terminal 365 amino acid residues does not undergo insulin-mediated receptor migration or aggregation. Endocrinology. 1993 Apr; 132(4):1453-62. PMID: 8462446.
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    292. Yip CC, Hsu H, Olefsky JM, Seely L. Preparation of N epsilon B28-monoazidobenzoyl insulin-like growth factor I and photoaffinity labeling of insulin-like growth factor I receptor. Peptides. 1993 Mar-Apr; 14(2):325-30. PMID: 8483809.
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    293. Olefsky JM. Insulin resistance and the pathogenesis of non-insulin dependent diabetes mellitus: cellular and molecular mechanisms. Adv Exp Med Biol. 1993; 334:129-50. PMID: 8249678.
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    294. Hsu D, Olefsky JM. Characterization of insulin-like growth factor (IGF) binding proteins and their role in modulating IGF-I action in BHK cells. J Biol Chem. 1992 Dec 15; 267(35):25576-82. PMID: 1281161.
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    295. Ciaraldi TP, el-Roeiy A, Madar Z, Reichart D, Olefsky JM, Yen SS. Cellular mechanisms of insulin resistance in polycystic ovarian syndrome. J Clin Endocrinol Metab. 1992 Aug; 75(2):577-83. PMID: 1322430.
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    296. Fink RI, Wallace P, Brechtel G, Olefsky JM. Evidence that glucose transport is rate-limiting for in vivo glucose uptake. Metabolism. 1992 Aug; 41(8):897-902. PMID: 1640870.
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    297. Grako KA, Olefsky JM, McClain DA. Tyrosine kinase-defective insulin receptors undergo decreased endocytosis but do not affect internalization of normal endogenous insulin receptors. Endocrinology. 1992 Jun; 130(6):3441-52. PMID: 1317784.
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    298. Takata Y, Webster NJ, Olefsky JM. Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites. J Biol Chem. 1992 May 05; 267(13):9065-70. PMID: 1577744.
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    299. Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care. 1992 Feb; 15(2):193-203. PMID: 1547676.
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    300. Anderson CM, Olefsky JM. Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors. J Biol Chem. 1991 Nov 15; 266(32):21760-4. PMID: 1657981.
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    301. Klauser R, Prager R, Schernthaner G, Olefsky JM. Contribution of postprandial insulin and glucose to glucose disposal in normal and insulin-resistant obese subjects. J Clin Endocrinol Metab. 1991 Oct; 73(4):758-64. PMID: 1890150.
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    302. Kusari J, Verma US, Buse JB, Henry RR, Olefsky JM. Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. J Clin Invest. 1991 Oct; 88(4):1323-30. PMID: 1918382.
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    303. Smith RM, Seely BL, Shah N, Olefsky JM, Jarett L. Tyrosine kinase-defective insulin receptors undergo insulin-induced microaggregation but do not concentrate in coated pits. J Biol Chem. 1991 Sep 15; 266(26):17522-30. PMID: 1910046.
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    304. Kassir AA, Upadhyay AK, Lim TJ, Moossa AR, Olefsky JM. Lack of effect of islet amyloid polypeptide in causing insulin resistance in conscious dogs during euglycemic clamp studies. Diabetes. 1991 Aug; 40(8):998-1004. PMID: 1860564.
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    305. Freidenberg GR, Suter SL, Henry RR, Reichart D, Olefsky JM. In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies. J Clin Invest. 1991 Jun; 87(6):2222-9. PMID: 1645756.
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    306. Takata Y, Webster NJ, Olefsky JM. Mutation of the two carboxyl-terminal tyrosines results in an insulin receptor with normal metabolic signaling but enhanced mitogenic signaling properties. J Biol Chem. 1991 May 15; 266(14):9135-9. PMID: 2026614.
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    307. Ciaraldi TP, Molina JM, Olefsky JM. Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: identification of multiple cellular defects in glucose transport. J Clin Endocrinol Metab. 1991 Apr; 72(4):876-82. PMID: 2005215.
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    308. Kusari J, Takata Y, Hatada E, Freidenberg G, Kolterman O, Olefsky JM. Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles. J Biol Chem. 1991 Mar 15; 266(8):5260-7. PMID: 2002058.
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    309. Kusari J, Olefsky JM, Strahl C, McClain DA. Insulin-receptor cDNA sequence in NIDDM patient homozygous for insulin-receptor gene RFLP. Diabetes. 1991 Feb; 40(2):249-54. PMID: 1671379.
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    310. Treadway JL, Morrison BD, Soos MA, Siddle K, Olefsky J, Ullrich A, McClain DA, Pessin JE. Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):214-8. PMID: 1846039.
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    311. Ciaraldi TP, Gilmore A, Olefsky JM, Goldberg M, Heidenreich KA. In vitro studies on the action of CS-045, a new antidiabetic agent. Metabolism. 1990 Oct; 39(10):1056-62. PMID: 2120548.
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    312. Williams JF, Olefsky JM. Defective insulin receptor function in down-regulated HepG2 cells. Endocrinology. 1990 Oct; 127(4):1706-17. PMID: 2169397.
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    313. Olefsky JM. The insulin receptor. A multifunctional protein. Diabetes. 1990 Sep; 39(9):1009-16. PMID: 2166696.
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    314. Edelman SV, Laakso M, Wallace P, Brechtel G, Olefsky JM, Baron AD. Kinetics of insulin-mediated and non-insulin-mediated glucose uptake in humans. Diabetes. 1990 Aug; 39(8):955-64. PMID: 1973673.
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    315. Laakso M, Edelman SV, Olefsky JM, Brechtel G, Wallace P, Baron AD. Kinetics of in vivo muscle insulin-mediated glucose uptake in human obesity. Diabetes. 1990 Aug; 39(8):965-74. PMID: 2197140.
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    316. Maegawa H, Kobayashi M, Egawa K, McClain DA, Olefsky JM, Shigeta Y. The ligand binding characteristics of a kinase-defective A/K1018 human insulin receptor expressed in Rat 1 fibroblasts. Biochim Biophys Acta. 1990 Jul 12; 1053(2-3):185-8. PMID: 2200525.
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    317. Williams JF, McClain DA, Dull TJ, Ullrich A, Olefsky JM. Characterization of an insulin receptor mutant lacking the subunit processing site. J Biol Chem. 1990 May 25; 265(15):8463-9. PMID: 2187866.
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    318. Thies RS, Molina JM, Ciaraldi TP, Freidenberg GR, Olefsky JM. Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects. Diabetes. 1990 Feb; 39(2):250-9. PMID: 2227134.
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    319. Molina JM, Cooper GJ, Leighton B, Olefsky JM. Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide. Diabetes. 1990 Feb; 39(2):260-5. PMID: 2227135.
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    320. McClain DA, Maegawa H, Thies RS, Olefsky JM. Dissection of the growth versus metabolic effects of insulin and insulin-like growth factor-I in transfected cells expressing kinase-defective human insulin receptors. J Biol Chem. 1990 Jan 25; 265(3):1678-82. PMID: 2153140.
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    321. Molina JM, Baron AD, Edelman SV, Brechtel G, Wallace P, Olefsky JM. Use of a variable tracer infusion method to determine glucose turnover in humans. Am J Physiol. 1990 Jan; 258(1 Pt 1):E16-23. PMID: 2405697.
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    322. Molina JM, Ciaraldi TP, Brady D, Olefsky JM. Decreased activation rate of insulin-stimulated glucose transport in adipocytes from obese subjects. Diabetes. 1989 Aug; 38(8):991-5. PMID: 2666204.
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    323. Hatada EN, McClain DA, Potter E, Ullrich A, Olefsky JM. Effects of growth and insulin treatment on the levels of insulin receptors and their mRNA in Hep G2 cells. J Biol Chem. 1989 Apr 25; 264(12):6741-7. PMID: 2540160.
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    324. Brillon DJ, Freidenberg GR, Henry RR, Olefsky JM. Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations. Diabetes. 1989 Mar; 38(3):397-403. PMID: 2465197.
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    325. Olefsky JM, Garvey WT, Henry RR, Brillon D, Matthaei S, Freidenberg GR. Cellular mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes. Am J Med. 1988 Nov 28; 85(5A):86-105. PMID: 3057897.
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    326. Brillon DJ, Henry RR, Klein HH, Olefsky JM, Freidenberg GR. Functional and structural differences in human and rat-derived insulin receptors: characterization of the beta-subunit kinase activity. Endocrinology. 1988 Oct; 123(4):1837-47. PMID: 2843349.
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    327. Freidenberg GR, Reichart D, Olefsky JM, Henry RR. Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss. J Clin Invest. 1988 Oct; 82(4):1398-406. PMID: 3170749.
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    328. Maegawa H, Olefsky JM, Thies S, Boyd D, Ullrich A, McClain DA. Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation. J Biol Chem. 1988 Sep 05; 263(25):12629-37. PMID: 2970462.
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    329. McClain DA, Henry RR, Ullrich A, Olefsky JM. Restriction-fragment-length polymorphism in insulin-receptor gene and insulin resistance in NIDDM. Diabetes. 1988 Aug; 37(8):1071-5. PMID: 2899037.
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    330. Maegawa H, McClain DA, Freidenberg G, Olefsky JM, Napier M, Lipari T, Dull TJ, Lee J, Ullrich A. Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects. J Biol Chem. 1988 Jun 25; 263(18):8912-7. PMID: 2837468.
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    331. McClain DA, Maegawa H, Levy J, Huecksteadt T, Dull TJ, Lee J, Ullrich A, Olefsky JM. Properties of a human insulin receptor with a COOH-terminal truncation. I. Insulin binding, autophosphorylation, and endocytosis. J Biol Chem. 1988 Jun 25; 263(18):8904-11. PMID: 2837467.
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    332. McClain DA, Olefsky JM. Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells. Diabetes. 1988 Jun; 37(6):806-15. PMID: 2838354.
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    333. Levy JR, Olefsky JM. Intracellular insulin-receptor dissociation and segregation in a rat fibroblast cell line transfected with a human insulin receptor gene. J Biol Chem. 1988 May 05; 263(13):6101-8. PMID: 3283119.
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    334. Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion. Diabetes. 1988 May; 37(5):590-9. PMID: 3282946.
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    335. Garvey WT, Huecksteadt TP, Matthaei S, Olefsky JM. Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus. J Clin Invest. 1988 May; 81(5):1528-36. PMID: 3366906.
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    336. Levy JR, Ullrich A, Olefsky JM. Endocytotic uptake, processing, and retroendocytosis of human biosynthetic proinsulin by rat fibroblasts transfected with the human insulin receptor gene. J Clin Invest. 1988 May; 81(5):1370-7. PMID: 3284910.
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    337. Matthaei S, Olefsky JM, Karnieli E. Cycloheximide decreases glucose transporters in rat adipocyte plasma membranes without affecting insulin-stimulated glucose transport. Biochem J. 1988 Apr 15; 251(2):491-7. PMID: 3041964.
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    338. Matthaei S, Olefsky JM, Horuk R. Biochemical characterization and subcellular distribution of the glucose transporter from rat brain microvessels. Biochim Biophys Acta. 1987 Dec 11; 905(2):417-25. PMID: 3318930.
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    339. Levy JR, Olefsky JM. The trafficking and processing of insulin and insulin receptors in cultured rat hepatocytes. Endocrinology. 1987 Dec; 121(6):2075-86. PMID: 3315635.
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    340. McClain DA, Maegawa H, Lee J, Dull TJ, Ulrich A, Olefsky JM. A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis. J Biol Chem. 1987 Oct 25; 262(30):14663-71. PMID: 3312193.
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    341. Klein HH, Freidenberg GR, Matthaei S, Olefsky JM. Insulin receptor kinase following internalization in isolated rat adipocytes. J Biol Chem. 1987 Aug 05; 262(22):10557-64. PMID: 3038888.
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    342. Klein HH, Ciaraldi TP, Freidenberg GR, Olefsky JM. Adenosine modulates insulin activation of insulin receptor kinase in intact rat adipocytes. Endocrinology. 1987 Jun; 120(6):2339-45. PMID: 3552635.
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    343. Prager R, Wallace P, Olefsky JM. Direct and indirect effects of insulin to inhibit hepatic glucose output in obese subjects. Diabetes. 1987 May; 36(5):607-11. PMID: 3552793.
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    344. Lavelle-Jones M, Scott MH, Kolterman O, Moossa AR, Olefsky JM. Non-insulin-mediated glucose uptake predominates in postabsorptive dogs. Am J Physiol. 1987 May; 252(5 Pt 1):E660-6. PMID: 2883896.
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    345. Baron AD, Wallace P, Olefsky JM. In vivo regulation of non-insulin-mediated and insulin-mediated glucose uptake by epinephrine. J Clin Endocrinol Metab. 1987 May; 64(5):889-95. PMID: 2881942.
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    346. Podlecki DA, Smith RM, Kao M, Tsai P, Huecksteadt T, Brandenburg D, Lasher RS, Jarett L, Olefsky JM. Nuclear translocation of the insulin receptor. A possible mediator of insulin's long term effects. J Biol Chem. 1987 Mar 05; 262(7):3362-8. PMID: 3546306.
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    347. Bergman RN, Prager R, Volund A, Olefsky JM. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest. 1987 Mar; 79(3):790-800. PMID: 3546379.
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    348. Prager R, Wallace P, Olefsky JM. Hyperinsulinemia does not compensate for peripheral insulin resistance in obesity. Diabetes. 1987 Mar; 36(3):327-34. PMID: 3542654.
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    349. Matthaei S, Garvey WT, Horuk R, Hueckstaedt TP, Olefsky JM. Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers. J Clin Invest. 1987 Mar; 79(3):703-9. PMID: 3102556.
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    350. Glauber HS, Henry RR, Wallace P, Frank BH, Galloway JA, Cohen RM, Olefsky JM. The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus. N Engl J Med. 1987 Feb 19; 316(8):443-9. PMID: 3543679.
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    351. Levy J, Olefsky JM. The effect of insulin concentration on retroendocytosis in isolated rat adipocytes. Endocrinology. 1987 Feb; 120(2):450-6. PMID: 3542501.
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    352. Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Selective suppression of hepatic glucose output by human proinsulin in the dog. Am J Physiol. 1987 Feb; 252(2 Pt 1):E230-6. PMID: 2881485.
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    353. May JM, Horuk R, Olefsky JM. Photolabeling of the adipocyte hexose carrier with an aryl azide derivative of maltose. Mol Cell Endocrinol. 1987 Feb; 49(2-3):181-8. PMID: 3556753.
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    354. Garvey WT, Olefsky JM, Matthaei S, Marshall S. Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance. J Biol Chem. 1987 Jan 05; 262(1):189-97. PMID: 3539929.
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    355. Freidenberg GR, Henry RR, Klein HH, Reichart DR, Olefsky JM. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. J Clin Invest. 1987 Jan; 79(1):240-50. PMID: 3540010.
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    356. Levy JR, Murray E, Manolagas S, Olefsky JM. Demonstration of insulin receptors and modulation of alkaline phosphatase activity by insulin in rat osteoblastic cells. Endocrinology. 1986 Oct; 119(4):1786-92. PMID: 3530724.
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    357. Matthaei S, Horuk R, Olefsky JM. Blood-brain glucose transfer in diabetes mellitus. Decreased number of glucose transporters at blood-brain barrier. Diabetes. 1986 Oct; 35(10):1181-4. PMID: 3530847.
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    358. Mandarino LJ, Madar Z, Kolterman OG, Bell JM, Olefsky JM. Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects. Am J Physiol. 1986 Oct; 251(4 Pt 1):E489-96. PMID: 3094377.
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    359. Henry RR, Wallace P, Olefsky JM. Effects of weight loss on mechanisms of hyperglycemia in obese non-insulin-dependent diabetes mellitus. Diabetes. 1986 Sep; 35(9):990-8. PMID: 3527829.
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    360. Madar Z, Olefsky J. Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet. Am J Clin Nutr. 1986 Aug; 44(2):206-11. PMID: 3728357.
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    361. Levy JR, Olefsky JM. Retroendocytosis of insulin in rat adipocytes. Endocrinology. 1986 Aug; 119(2):572-9. PMID: 3525121.
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    362. Prager R, Wallace P, Olefsky JM. In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects. J Clin Invest. 1986 Aug; 78(2):472-81. PMID: 3525609.
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    363. Huecksteadt T, Olefsky JM, Brandenberg D, Heidenreich KA. Recycling of photoaffinity-labeled insulin receptors in rat adipocytes. Dissociation of insulin-receptor complexes is not required for receptor recycling. J Biol Chem. 1986 Jul 05; 261(19):8655-9. PMID: 3522577.
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    364. Shoelson SE, Marshall S, Horikoshi H, Kolterman OG, Rubenstein AH, Olefsky JM. Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes. J Clin Endocrinol Metab. 1986 Jul; 63(1):56-61. PMID: 3486878.
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    365. Fink RI, Wallace P, Olefsky JM. Effects of aging on glucose-mediated glucose disposal and glucose transport. J Clin Invest. 1986 Jun; 77(6):2034-41. PMID: 3519685.
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    366. Klein HH, Freidenberg GR, Kladde M, Olefsky JM. Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo. J Biol Chem. 1986 Apr 05; 261(10):4691-7. PMID: 3007472.
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    367. Glauber HS, Wallace P, Galloway J, Frank BH, Olefsky JM. The effects of proinsulin pretreatment on the combined actions of insulin and proinsulin in normal man. J Clin Endocrinol Metab. 1986 Apr; 62(4):785-8. PMID: 3512594.
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    368. Maller JL, Pike LJ, Freidenberg GR, Cordera R, Stith BJ, Olefsky JM, Krebs EG. Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes. Nature. 1986 Apr 3-9; 320(6061):459-61. PMID: 3083266.
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    369. Garvey WT, Olefsky JM, Marshall S. Insulin induces progressive insulin resistance in cultured rat adipocytes. Sequential effects at receptor and multiple postreceptor sites. Diabetes. 1986 Mar; 35(3):258-67. PMID: 3512337.
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    370. Ciaraldi TP, Brady D, Olefsky JM. Kinetics of biosynthetic human proinsulin action in isolated rat adipocytes. Diabetes. 1986 Mar; 35(3):318-23. PMID: 3512342.
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    371. Horuk R, Matthaei S, Olefsky JM, Baly DL, Cushman SW, Simpson IA. Biochemical and functional heterogeneity of rat adipocyte glucose transporters. J Biol Chem. 1986 Feb 05; 261(4):1823-8. PMID: 3511051.
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    372. Jochen AL, Berhanu P, Olefsky JM. Insulin internalization and degradation in adipocytes from normal and type II diabetic subjects. J Clin Endocrinol Metab. 1986 Feb; 62(2):268-74. PMID: 3510222.
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    373. Henry RR, Wiest-Kent TA, Scheaffer L, Kolterman OG, Olefsky JM. Metabolic consequences of very-low-calorie diet therapy in obese non-insulin-dependent diabetic and nondiabetic subjects. Diabetes. 1986 Feb; 35(2):155-64. PMID: 3510922.
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    374. Freidenberg GR, Klein HH, Kladde MP, Cordera R, Olefsky JM. Regulation of epidermal growth factor receptor number and phosphorylation by fasting in rat liver. J Biol Chem. 1986 Jan 15; 261(2):752-7. PMID: 3001081.
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    375. Baron AD, Kolterman OG, Bell J, Mandarino LJ, Olefsky JM. Rates of noninsulin-mediated glucose uptake are elevated in type II diabetic subjects. J Clin Invest. 1985 Nov; 76(5):1782-8. PMID: 2865274.
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    376. Henry RR, Scheaffer L, Olefsky JM. Glycemic effects of intensive caloric restriction and isocaloric refeeding in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1985 Nov; 61(5):917-25. PMID: 4044780.
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    377. Freidenberg GR, Klein HH, Cordera R, Olefsky JM. Insulin receptor kinase activity in rat liver. Regulation by fasting and high carbohydrate feeding. J Biol Chem. 1985 Oct 15; 260(23):12444-53. PMID: 2995376.
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    378. Olefsky JM, Ciaraldi TP, Kolterman OG. Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes. Am J Med. 1985 Sep 20; 79(3B):12-22. PMID: 3901744.
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    379. Olefsky JM. Clinical, cellular, and physiologic effects of glyburide in non-insulin-dependent diabetes mellitus. Am J Med. 1985 Sep 20; 79(3B):109-12. PMID: 3931458.
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    380. Horuk R, Olefsky JM. Post-binding events in insulin action. Mol Cell Endocrinol. 1985 Aug; 42(1):1-20. PMID: 3896892.
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    381. Garvey WT, Olefsky JM, Marshall S. Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytes. J Clin Invest. 1985 Jul; 76(1):22-30. PMID: 3894420.
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    382. Garvey WT, Olefsky JM, Griffin J, Hamman RF, Kolterman OG. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes. 1985 Mar; 34(3):222-34. PMID: 3882489.
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    383. Garvey WT, Revers RR, Kolterman OG, Rubenstein AH, Olefsky JM. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus. J Clin Endocrinol Metab. 1985 Mar; 60(3):559-68. PMID: 3882736.
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    384. Fink RI, Revers RR, Kolterman OG, Olefsky JM. The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging. Diabetes. 1985 Mar; 34(3):275-80. PMID: 3882495.
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    385. Klein HH, Freidenberg GR, Cordera R, Olefsky JM. Substrate specificities of insulin and epidermal growth factor receptor kinases. Biochem Biophys Res Commun. 1985 Feb 28; 127(1):254-63. PMID: 2983709.
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    386. Heidenreich KA, Yip CC, Frank BH, Olefsky JM. The preparation and characterization of mono-iodinated photoreactive analogs of insulin. Biochem Biophys Res Commun. 1985 Feb 15; 126(3):1138-45. PMID: 3884003.
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    387. Freidenberg GR, Olefsky JM. Dissociation of insulin resistance and decreased insulin receptor binding in Duchenne muscular dystrophy. J Clin Endocrinol Metab. 1985 Feb; 60(2):320-7. PMID: 3965491.
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    388. Horuk R, Olefsky JM. Post binding events in insulin action. Diabetes Metab Rev. 1985; 1(1-2):59-97. PMID: 3915252.
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    389. Olefsky JM, Revers RR, Prince M, Henry RR, Garvey WT, Scarlett JA, Kolterman OG. Insulin resistance in non-insulin dependent (type II) and insulin dependent (type I) diabetes mellitus. Adv Exp Med Biol. 1985; 189:176-205. PMID: 3898763.
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    390. Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Rubenstein A, Frank B, Galloway J, Olefsky JM. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal. J Clin Endocrinol Metab. 1984 Jun; 58(6):1094-8. PMID: 6373809.
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    391. Bergenstal RM, Cohen RM, Lever E, Polonsky K, Jaspan J, Blix PM, Revers R, Olefsky JM, Kolterman O, Steiner K. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. J Clin Endocrinol Metab. 1984 Jun; 58(6):973-9. PMID: 6373814.
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    392. Heidenreich KA, Brandenburg D, Berhanu P, Olefsky JM. Metabolism of photoaffinity-labeled insulin receptors by adipocytes. Role of internalization, degradation, and recycling. J Biol Chem. 1984 May 25; 259(10):6511-5. PMID: 6373760.
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    393. Fink RI, Kolterman OG, Olefsky JM. The physiological significance of the glucose intolerance of aging. J Gerontol. 1984 May; 39(3):273-8. PMID: 6371116.
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    394. Kolterman OG, Olefsky JM. The impact of sulfonylurea treatment upon the mechanisms responsible for the insulin resistance in type II diabetes. Diabetes Care. 1984 May-Jun; 7 Suppl 1:81-8. PMID: 6376033.
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    395. Fink RI, Kolterman OG, Kao M, Olefsky JM. The role of the glucose transport system in the postreceptor defect in insulin action associated with human aging. J Clin Endocrinol Metab. 1984 Apr; 58(4):721-5. PMID: 6699133.
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    396. Kolterman OG, Gray RS, Shapiro G, Scarlett JA, Griffin J, Olefsky JM. The acute and chronic effects of sulfonylurea therapy in type II diabetic subjects. Diabetes. 1984 Apr; 33(4):346-54. PMID: 6423429.
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    397. Revers RR, Fink R, Griffin J, Olefsky JM, Kolterman OG. Influence of hyperglycemia on insulin's in vivo effects in type II diabetes. J Clin Invest. 1984 Mar; 73(3):664-72. PMID: 6368585.
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    398. Podlecki DA, Frank BH, Olefsky JM. In vitro characterization of biosynthetic human proinsulin. Diabetes. 1984 Feb; 33(2):111-8. PMID: 6363165.
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    399. Revers RR, Kolterman OG, Scarlett JA, Gray RS, Olefsky JM. Lack of in vivo insulin resistance in controlled insulin-dependent, type I, diabetic patients. J Clin Endocrinol Metab. 1984 Feb; 58(2):353-8. PMID: 6363437.
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    400. Berhanu P, Kolterman OG, Baron A, Tsai P, Olefsky JM, Brandenburg D. Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing. J Clin Invest. 1983 Dec; 72(6):1958-70. PMID: 6358259.
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    401. Green A, Frank BH, Rubenstein A, Tager H, Olefsky JM. Characteristics of binding of a low affinity, noncooperative insulin [( LeuB25]insulin) to IM-9 lymphocytes. Endocrinology. 1983 Dec; 113(6):1963-71. PMID: 6357764.
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    402. Heidenreich KA, Berhanu P, Brandenburg D, Olefsky JM. Degradation of insulin receptors in rat adipocytes. Diabetes. 1983 Nov; 32(11):1001-9. PMID: 6357900.
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    403. Marshall S, Olefsky JM. Separate intracellular pathways for insulin receptor recycling and insulin degradation in isolated rat adipocytes. J Cell Physiol. 1983 Nov; 117(2):195-203. PMID: 6355127.
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    404. Ciaraldi TP, Olefsky JM. Length of acute exposure to insulin regulates the rate of deactivation of stimulated glucose transport in isolated rat adipocytes. Endocrinology. 1983 Nov; 113(5):1739-45. PMID: 6354696.
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    405. Ciaraldi TP, Olefsky JM. Effect of temperature on coupling of insulin receptors to stimulation of glucose transport in isolated rat adipocytes. Metabolism. 1983 Oct; 32(10):1002-8. PMID: 6350807.
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    406. Podlecki DA, Frank BH, Kao M, Horikoshi H, Freidenberg G, Marshall S, Ciaraldi T, Olefsky JM. Characterization of the receptor binding properties of monoiodoinsulin isomers and the identification of different insulin receptor specificities in hepatic and extrahepatic tissues. Diabetes. 1983 Aug; 32(8):697-704. PMID: 6347766.
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    407. Heidenreich KA, Zahniser NR, Berhanu P, Brandenburg D, Olefsky JM. Structural differences between insulin receptors in the brain and peripheral target tissues. J Biol Chem. 1983 Jul 25; 258(14):8527-30. PMID: 6345543.
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    408. Crapo PA, Olefsky JM. Food fallacies and blood sugar. N Engl J Med. 1983 Jul 07; 309(1):44-5. PMID: 6855853.
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    409. Marshall S, Podlecki DA, Olefsky JM. Low pH accelerates dissociation of receptor-bound insulin. Endocrinology. 1983 Jul; 113(1):37-42. PMID: 6345144.
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    410. Revers RR, Kolterman OG, Olefsky JM. Relationship between serum glucose level and the metabolic clearance rate of glucose in non-insulin-dependent diabetes mellitus. Diabetes. 1983 Jul; 32(7):627-32. PMID: 6345242.
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    411. Freidenberg GF, Kao M, Olefsky JM. Insulin binding to erythrocytes incubated in vitro at physiological temperature. J Clin Endocrinol Metab. 1983 Jul; 57(1):107-14. PMID: 6343415.
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    412. Massague J, Freidenberg GF, Olefsky JM, Czech MP. Parallel decreases in the expression of receptors for insulin and insulin-like growth factor I in a mutant human fibroblast line. Diabetes. 1983 Jun; 32(6):541-4. PMID: 6313454.
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    413. Fink RI, Kolterman OG, Griffin J, Olefsky JM. Mechanisms of insulin resistance in aging. J Clin Invest. 1983 Jun; 71(6):1523-35. PMID: 6345584.
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    414. Scarlett JA, Kolterman OG, Ciaraldi TP, Kao M, Olefsky JM. Insulin treatment reverses the postreceptor defect in adipocyte 3-O-methylglucose transport in type II diabetes mellitus. J Clin Endocrinol Metab. 1983 Jun; 56(6):1195-201. PMID: 6341390.
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    415. Kolterman OG, Prince MJ, Olefsky JM. Insulin resistance in noninsulin-dependent diabetes mellitus: impact of sulfonylurea agents in vivo and in vitro. Am J Med. 1983 Jan 17; 74(1A):82-101. PMID: 6401923.
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    416. Elders MJ, Schedewie HK, Olefsky J, Givens B, Char F, Bier DM, Baldwin D, Fiser RH, Seyedabadi S, Rubenstein A. Endocrine-metabolic relationships in patients with leprechaunism. J Natl Med Assoc. 1982 Dec; 74(12):1195-210. PMID: 7154104.
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    417. Olefsky JM. Insulin resistance in humans. Gastroenterology. 1982 Dec; 83(6):1313-8. PMID: 6751927.
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    418. Berhanu P, Tsai P, Olefsky JM. Insulin-stimulated glucose transport in cultured fibroblasts from normal and noninsulin-dependent (type II) diabetic human subjects. J Clin Endocrinol Metab. 1982 Dec; 55(6):1226-30. PMID: 6752171.
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    419. Ciaraldi TP, Kolterman OG, Scarlett JA, Kao M, Olefsky JM. Role of glucose transport in the postreceptor defect of non-insulin-dependent diabetes mellitus. Diabetes. 1982 Nov; 31(11):1016-22. PMID: 6757010.
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    420. Gray RS, Scarlett JA, Griffin J, Olefsky JM, Kolterman OG. In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man. Diabetes. 1982 Oct; 31(10):929-36. PMID: 6759226.
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    421. Crapo PA, Scarlett JA, Kolterman OG, Sanders LR, Hofeldt FD, Olefsky JM. The effects of oral fructose, sucrose, and glucose in subjects with reactive hypoglycemia. Diabetes Care. 1982 Sep-Oct; 5(5):512-7. PMID: 6765227.
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    422. Olefsky JM, Saekow M. Mechanisms of insulin degradation by isolated rat adipocytes. Mol Cell Biochem. 1982 Aug 20; 47(1):23-9. PMID: 6752691.
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    423. Olefsky JM, Kao M. Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes. J Biol Chem. 1982 Aug 10; 257(15):8667-73. PMID: 7047524.
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    424. Green A, Tager H, Rubenstein A, Frank B, Olefsky JM. Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes. FEBS Lett. 1982 Aug 02; 144(2):255-8. PMID: 6749549.
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    425. Ciaraldi TP, Olefsky JM. Kinetic relationships between insulin receptor binding and effects on glucose transport in isolated rat adipocytes. Biochemistry. 1982 Jul 06; 21(14):3475-80. PMID: 7052124.
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    426. Olefsky JM, Marshall S, Berhanu P, Saekow M, Heidenreich K, Green A. Internalization and intracellular processing of insulin and insulin receptors in adipocytes. Metabolism. 1982 Jul; 31(7):670-90. PMID: 7045573.
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    427. Scarlett JA, Gray RS, Griffin J, Olefsky JM, Kolterman OG. Insulin treatment reverses the insulin resistance of type II diabetes mellitus. Diabetes Care. 1982 Jul-Aug; 5(4):353-63. PMID: 6759075.
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    428. Kolterman OG, Scarlett JA, Olefsky JM. Insulin resistance in non-insulin-dependent, type II diabetes mellitus. Clin Endocrinol Metab. 1982 Jul; 11(2):363-88. PMID: 6754161.
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    429. Olefsky JM, Kolterman OG, Scarlett JA. Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus. Am J Physiol. 1982 Jul; 243(1):E15-30. PMID: 7046470.
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    430. Scarlett JA, Kolterman OG, Moore P, Saekow M, Insel J, Griffin J, Mako M, Rubenstein AH, Olefsky JM. Insulin resistance and diabetes due to a genetic defect in insulin receptors. J Clin Endocrinol Metab. 1982 Jul; 55(1):123-31. PMID: 7042734.
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    431. Berhanu P, Olefsky JM, Tsai P, Thamm P, Saunders D, Brandenburg D. Internalization and molecular processing of insulin receptors in isolated rat adipocytes. Proc Natl Acad Sci U S A. 1982 Jul; 79(13):4069-73. PMID: 7051001.
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    432. Berhanu P, Olefsky JM. Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation. Diabetes. 1982 May; 31(5 Pt 1):410-7. PMID: 7152133.
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    433. Ciaraldi TP, Olefsky JM. Comparison of the effects of insulin and H2O2 on adipocyte glucose transport. J Cell Physiol. 1982 Mar; 110(3):323-8. PMID: 7045141.
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    434. Green A, Olefsky JM. Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes. Proc Natl Acad Sci U S A. 1982 Jan; 79(2):427-31. PMID: 7043460.
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    435. Olefsky JM, Saekow M, Kroc RL. Potentiation of insulin binding and insulin action by purified porcine relaxin. Ann N Y Acad Sci. 1982; 380:200-16. PMID: 7044233.
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    436. Gray RS, Olefsky JM. Effect of a glucosidase inhibitor on the metabolic response of diabetic rats to a high carbohydrate diet, consisting of starch and sucrose, or glucose. Metabolism. 1982 Jan; 31(1):88-92. PMID: 7043164.
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    437. Roth SI, Schedewie HK, Bier DM, Conaway HH, Olefsky J, Rubenstein A, Elders MJ. Hepatic ultrastructure in leprechaunism. Hepatic ultrastructural evidence suggesting a syndrome with defective hepatic glucose release. Virchows Arch A Pathol Anat Histol. 1982; 397(2):121-30. PMID: 7179734.
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    438. Marshall S, Green A, Olefsky JM. Evidence for recycling of insulin receptors in isolated rat adipocytes. J Biol Chem. 1981 Nov 25; 256(22):11464-70. PMID: 7028734.
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    439. Prince MJ, Baldwin D, Tsai P, Olefsky JM. Regulation of insulin receptors in cultured human fibroblasts. Endocrinology. 1981 Nov; 109(5):1754-9. PMID: 7297502.
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    440. Rosenfeld RG, Baldwin D, Dollar LA, Hintz RL, Olefsky JM, Rubenstein A. Simultaneous inhibition of insulin and somatomedin-C binding to cultured IM-9 lymphocytes by naturally occurring antireceptor antibodies. Diabetes. 1981 Nov; 30(11):979-82. PMID: 6271619.
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    441. Kolterman OG, Gray RS, Griffin J, Burstein P, Insel J, Scarlett JA, Olefsky JM. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J Clin Invest. 1981 Oct; 68(4):957-69. PMID: 7287908.
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    442. Ciaraldi TP, Kolterman OG, Olefsky JM. Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity. J Clin Invest. 1981 Oct; 68(4):875-80. PMID: 7026616.
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    443. Marshall S, Olefsky JM. Tris (hydroxmethyl) aminomethane permits the expression of insulin-induced receptor loss in isolated rat adipocytes. Biochem Biophys Res Commun. 1981 Sep 30; 102(2):646-53. PMID: 7030343.
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    444. Baldwin D, Prince M, Tsai P, Johnson C, Lotan R, Rubenstein AH, Olefsky JM. Insulin binding, internalization, and receptor regulation in cultured human fibroblasts. Am J Physiol. 1981 Sep; 241(3):E251-60. PMID: 7025657.
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    445. Roth SI, Schedewie HK, Herzberg VK, Olefsky J, Elders MJ, Rubenstein A. Cutaneous manifestations of leprechaunism. Arch Dermatol. 1981 Sep; 117(9):531-5. PMID: 7294844.
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    446. Marshall S, Olefsky JM. Characterization of insulin-induced receptor loss and evidence for internalization of the insulin receptor. Diabetes. 1981 Sep; 30(9):746-53. PMID: 7021273.
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    447. De Pirro R, Green A, Kao MY, Olefsky JM. Effects of prednisolone and dexamethasone in vivo and in vitro: studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes. Diabetologia. 1981 Aug; 21(2):149-53. PMID: 7021286.
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    448. Olefsky JM, Green A, Ciaraldi TP, Saekow M, Rubenstein AH, Tager HS. Relationship between negative cooperativity and insulin action. Biochemistry. 1981 Jul 21; 20(15):4488-92. PMID: 7025901.
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    449. Prince MJ, Tsai P, Olefsky JM. Insulin binding, internalization, and insulin receptor regulation in fibroblasts from type II, non-insulin-dependent diabetic subjects. Diabetes. 1981 Jul; 30(7):596-600. PMID: 7018965.
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    450. Berhanu P, Olefsky JM. Effects of insulin and insulin-like agents on the glucose transport system of cultured human fibroblasts. Diabetes. 1981 Jun; 30(6):523-9. PMID: 7014316.
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    451. Ciaraldi TP, Olefsky JM. Metabolic requirements for deactivation of insulin-stimulated glucose transport in isolated rat adipocytes. Arch Biochem Biophys. 1981 May; 208(2):502-7. PMID: 7020602.
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    452. Moore P, Kolterman O, Weyant J, Olefsky JM. Insulin binding in human pregnancy: comparisons to the postpartum, luteal, and follicular states. J Clin Endocrinol Metab. 1981 May; 52(5):937-41. PMID: 7014589.
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    453. Crapo PA, Reaven GM, Olefsky JM. Hormonal and substrate responses to a standard meal in normal and hypertriglyceridemic subjects. Metabolism. 1981 Apr; 30(4):331-4. PMID: 7010076.
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    454. Olefsky JM. Insulin binding, biologic activity, and metabolism of biosynthetic human insulin. Diabetes Care. 1981 Mar-Apr; 4(2):244-7. PMID: 7011736.
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    455. Olefsky JM. LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective. Diabetes. 1981 Feb; 30(2):148-62. PMID: 7009267.
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    456. Olefsky JM, Kolterman OG. Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes. Am J Med. 1981 Jan; 70(1):151-68. PMID: 7006388.
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    457. Marshall S, Olefsky JM. The endocytotic-internalization pathway of insulin metabolism: relationship to insulin degradation and activation of glucose transport. Endocrinology. 1980 Dec; 107(6):1937-45. PMID: 7000505.
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    458. Saekow M, Olefsky JM. Effect of a high carbohydrate diet on adipocyte glucose metabolism in spontaneously obese rats and insulin-deficient diabetic rats. Endocrinology. 1980 Dec; 107(6):2004-10. PMID: 7428703.
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    459. Bier DM, Schedewie H, Larner J, Olefsky J, Rubenstein A, Fiser RH, Craig JW, Elders MJ. Glucose kinetics in leprechaunism: accelerated fasting due to insulin resistance. J Clin Endocrinol Metab. 1980 Nov; 51(5):988-94. PMID: 6999010.
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    460. Baldwin D, Prince M, Marshall S, Davies P, Olefsky JM. Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway. Proc Natl Acad Sci U S A. 1980 Oct; 77(10):5975-8. PMID: 6108561.
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    461. Marshall S, Olefsky JM. Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. J Clin Invest. 1980 Oct; 66(4):763-72. PMID: 6999035.
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    462. Kolterman OG, Olefsky JM, Kurahara C, Taylor K. A defect in cell-mediated immune function in insulin-resistant diabetic and obese subjects. J Lab Clin Med. 1980 Sep; 96(3):535-43. PMID: 6995542.
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    463. Prince MJ, Olefsky JM. Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors. J Clin Invest. 1980 Sep; 66(3):608-11. PMID: 6772676.
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    464. Crapo PA, Kolterman OG, Olefsky JM. Effects of oral fructose in normal, diabetic, and impaired glucose tolerance subjects. Diabetes Care. 1980 Sep-Oct; 3(5):575-82. PMID: 7002511.
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    465. Crapo PA, Kolterman OG, Waldeck N, Reaven GM, Olefsky JM. Postprandial hormonal responses to different types of complex carbohydrate in individuals with impaired glucose tolerance. Am J Clin Nutr. 1980 Aug; 33(8):1723-8. PMID: 6996472.
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    466. Olefsky JM, Saekow M, Tager H, Rubenstein AH. Characterization of a mutant human insulin species. J Biol Chem. 1980 Jul 10; 255(13):6098-105. PMID: 6993466.
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    467. Tager H, Thomas N, Assoian R, Rubenstein A, Saekow M, Olefsky J, Kaiser ET. Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. Proc Natl Acad Sci U S A. 1980 Jun; 77(6):3181-5. PMID: 6997872.
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    468. Greenfield M, Kolterman O, Olefsky J, Reaven GM. Mechanism of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia. Diabetologia. 1980 Jun; 18(6):441-6. PMID: 7418956.
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    469. Kolterman OG, Insel J, Saekow M, Olefsky JM. Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. J Clin Invest. 1980 Jun; 65(6):1272-84. PMID: 6997333.
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    470. Siegel J, Olefsky JM. Role of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytes. Biochemistry. 1980 May 13; 19(10):2183-90. PMID: 6990973.
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    471. Olefsky JM, Crapo P. Fructose, xylitol, and sorbitol. Diabetes Care. 1980 Mar-Apr; 3(2):390-3. PMID: 7389552.
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    472. Insel JR, Kolterman OG, Saekow M, Olefsky JM. Short-term regulation of insulin receptor affinity in man. Diabetes. 1980 Feb; 29(2):132-9. PMID: 6986298.
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    473. Ciaraldi TP, Olefsky JM. Relationship between deactivation of insulin-stimulated glucose transport and insulin dissociation in isolated rat adipocytes. J Biol Chem. 1980 Jan 25; 255(2):327-30. PMID: 7356614.
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    474. Given BD, Mako ME, Tager HS, Baldwin D, Markese J, Rubenstein AH, Olefsky J, Kobayashi M, Kolterman O, Poucher R. Diabetes due to secretion of an abnormal insulin. N Engl J Med. 1980 Jan 17; 302(3):129-35. PMID: 7350438.
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    475. Olefsky JM, Kolterman OG. Pancreas. Clin Endocrinol Metab. 1979 Nov; 8(3):579-601. PMID: 389492.
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    476. Marshall S, Olefsky JM. Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation. J Biol Chem. 1979 Oct 25; 254(20):10153-60. PMID: 489589.
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    477. Tager H, Given B, Baldwin D, Mako M, Markese J, Rubenstein A, Olefsky J, Kobayashi M, Kolterman O, Poucher R. A structurally abnormal insulin causing human diabetes. Nature. 1979 Sep 13; 281(5727):122-5. PMID: 381941.
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    478. Kolterman OG, Greenfield M, Reaven GM, Saekow M, Olefsky JM. Effect of a high carbohydrate diet on insulin binding to adipocytes and on insulin action in vivo in man. Diabetes. 1979 Aug; 28(8):731-6. PMID: 446930.
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    479. Kobayashi M, Olefsky JM. Effect of experimental hyperinsulinaemia on intracellular glucose metabolism of isolated adipocytes. Diabetologia. 1979 Aug; 17(2):111-6. PMID: 488566.
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    480. Ciaraldi TP, Kolterman OG, Siegel JA, Olefsky JM. Insulin-stimulated glucose transport in human adipocytes. Am J Physiol. 1979 Jun; 236(6):E621-5. PMID: 443417.
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    481. Olefsky JM, Kobayashi M, Chang H. Interactions between insulin and its receptors after the initial binding event. Functional heterogeneity and relationships to insulin degradation. Diabetes. 1979 May; 28(5):460-71. PMID: 437375.
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    482. Kolterman OG, Saekow M, Olefsky JM. The effects of acute and chronic starvation on insulin binding to isolated human adipocytes. J Clin Endocrinol Metab. 1979 May; 48(5):836-42. PMID: 429529.
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    483. Ciaraldi TP, Olefsky JM. Coupling of insulin receptors to glucose transport: a temperature-dependent time lag in activation of glucose transport. Arch Biochem Biophys. 1979 Mar; 193(1):221-31. PMID: 453850.
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    484. Kolterman OG, Reaven GM, Olefsky JM. Relationship between in vivo insulin resistance and decreased insulin receptors in obese man. J Clin Endocrinol Metab. 1979 Mar; 48(3):487-94. PMID: 429500.
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    485. Olefsky JM. Comparison of the effects of insulin and insulin-like agents on different aspects of adipocyte metabolism. Horm Metab Res. 1979 Mar; 11(3):209-13. PMID: 447201.
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    486. Olefsky JM, Chang H. Further evidence for functional heterogeneity of adipocyte insulin receptors. Endocrinology. 1979 Feb; 104(2):462-6. PMID: 446370.
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    487. Kobayashi M, Olefsky JM. Effects of streptozotocin-induced diabetes on insulin binding, glucose transport, and intracellular glucose metabolism in isolated rat adipocytes. Diabetes. 1979 Feb; 28(2):87-95. PMID: 154427.
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    488. Davis BM, Bernstein R, Kolterman O, Olefsky JM, Reaven GM. Defect in glucose removal in nonketotic diabetic patients with fasting hyperglycemia. Diabetes. 1979 Jan; 28(1):32-4. PMID: 569610.
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    489. Olefsky JM, Saekow M. The effects of dietary carbohydrate content on insulin binding and glucose metabolism by isolated rat adipocytes. Endocrinology. 1978 Dec; 103(6):2252-63. PMID: 748046.
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    490. Greenfield M, Kolterman O, Olefsky JM, Reaven GM. The effect of ten days of fasting on various aspects of carbohydrate metabolism in obese diabetic subjects with significant fasting hyperglycemia. Metabolism. 1978 Dec; 27(12 Suppl 2):1839-52. PMID: 723636.
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    491. Olefsky JM, Kobayashi M. Ability of circulating insulin to chronically regulate the cellular glucose transport system. Metabolism. 1978 Dec; 27(12 Suppl 2):1917-29. PMID: 723641.
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    492. Olefsky JM, Chang H. Insulin binding to adipocytes. Evidence for functionally distinct receptors. Diabetes. 1978 Sep; 27(9):946-58. PMID: 689306.
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    493. Kobayashi M, Olefsky JM. Effect of experimental hyperinsulinemia on insulin binding and glucose transport in isolated rat adipocytes. Am J Physiol. 1978 Jul; 235(1):E53-62. PMID: 677310.
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    494. Kobayashi M, Olefsky JM, Elders J, Mako ME, Given BD, Schedwie HK, Fiser RH, Hintz RL, Horner JA, Rubenstein AH. Insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3469-73. PMID: 277948.
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    495. Kobayashi M, Olefsky JM. Long-term regulation of adipocyte glucose transport capacity by circulating insulin in rats. J Clin Invest. 1978 Jul; 62(1):73-81. PMID: 659640.
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    496. Olefsky JM. Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes. Biochem J. 1978 Apr 15; 172(1):137-45. PMID: 656068.
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    497. Bernstein RM, Davis BM, Olefsky JM, Reaven GM. Hepatic insulin responsiveness in patients with endogenous hypertriglyceridaemia. Diabetologia. 1978 Apr; 14(4):249-53. PMID: 205476.
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    498. Olefsky JM, Kobayashi M. Mechanisms of fasting-induced increase in insulin binding to rat adipocytes. J Clin Invest. 1978 Feb; 61(2):329-38. PMID: 621276.
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    499. Reaven GM, Olefsky JM. The role of insulin resistance in the pathogenesis of diabetes mellitus. Adv Metab Disord. 1978; 9:313-31. PMID: 417568.
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    500. Crapo PA, Reaven G, Olefsky J. Postprandial plasma-glucose and -insulin responses to different complex carbohydrates. Diabetes. 1977 Dec; 26(12):1178-83. PMID: 590639.
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    501. Scarlett JA, Mako ME, Rubenstein AH, Blix PM, Goldman J, Horwitz DL, Tager H, Jaspan JB, Stjernholm MR, Olefsky JM. Factitious hypoglycemia. Diagnosis by measurement of serum C-peptide immunoreactivity and insulin-binding antibodies. N Engl J Med. 1977 Nov 10; 297(19):1029-32. PMID: 198659.
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    502. Olefsky JM, Sperling MA, Reaven GM. Does glucagon play a role in the insulin resistance of patients with adult non-ketotic diabetes? Diabetologia. 1977 Aug; 13(4):327-30. PMID: 913924.
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    503. Olefsky JM. Insensitivity of large rat adipocytes to the antilipolytic effects of insulin. J Lipid Res. 1977 Jul; 18(4):459-64. PMID: 894138.
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    504. Olefsky JM, Reaven GM. Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity. Diabetes. 1977 Jul; 26(7):680-8. PMID: 873075.
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    505. Reaven GM, Olefsky JM. Relationship between heterogeneity of insulin responses and insulin resistance in normal subjects and patients with chemical diabetes. Diabetologia. 1977 May; 13(3):201-6. PMID: 873087.
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    506. Olefsky JM. Mechanisms of decreased insulin responsiveness of large adipocytes. Endocrinology. 1977 Apr; 100(4):1169-77. PMID: 837879.
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    507. Olefsky JM. Interaction between insulin receptors and glucose transport: effect of prostaglandin E2. Biochem Biophys Res Commun. 1977 Mar 21; 75(2):271-6. PMID: 851438.
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    508. Olefsky JM. The insulin receptor: its role in insulin resistance of obesity and diabetes. Diabetes. 1976 Dec; 25(12):1154-62. PMID: 791735.
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    509. Olefsky JM. Effects of fasting on insulin binding, glucose transport, and glucose oxidation in isolated rat adipocytes: relationships between insulin receptors and insulin action. J Clin Invest. 1976 Dec; 58(6):1450-60. PMID: 993354.
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    510. Crapo PA, Reaven G, Olefsky J. Plasma glucose and insulin responses to orally administered simple and complex carbohydrates. Diabetes. 1976 Sep; 25(9):741-7. PMID: 955301.
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    511. Kimmerling G, Javorski C, Olefsky JM, Reaven GM. Locating the site(s) of insulin resistance in patients with nonketotic diabetes mellitus. Diabetes. 1976 Aug; 25(8):673-8. PMID: 955298.
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    512. Olefsky JM. Insulin's effect on glucose oxidation independent of glucose transport. Biochem Biophys Res Commun. 1976 Jul 12; 71(1):106-13. PMID: 962906.
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    513. Olefsky JM, Reaven GM. Insulin binding to monocytes and total mononuclear leukocytes from normal and diabetic patients. J Clin Endocrinol Metab. 1976 Jul; 43(1):226-31. PMID: 947940.
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    514. Olefsky JM. Decreased insulin binding to adipocytes and circulating monocytes from obese subjects. J Clin Invest. 1976 May; 57(5):1165-72. PMID: 177453.
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    515. Olefsky JM, Crapo P, Reaven GM. Postprandial plasma triglyceride and cholesterol responses to a low-fat meal. Am J Clin Nutr. 1976 May; 29(5):535-9. PMID: 178167.
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    516. Ginsberg H, Olefsky JM, Kimmerling G, Crapo P, Reaven GM. Induction of hypertriglyceridemia by a low-fat diet. J Clin Endocrinol Metab. 1976 Apr; 42(4):729-35. PMID: 1262445.
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    517. Olefsky JM. The effects of spontaneous obesity on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest. 1976 Apr; 57(4):842-51. PMID: 181402.
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    518. Olefsky JM, Kimmerling G. Effects of glucocorticoids on carbohydrate metabolism. Am J Med Sci. 1976 Mar-Apr; 271(2):202-10. PMID: 178180.
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    519. Olefsky J, Bacon VC, Baur S. Insulin receptors of skeletal muscle: specific insulin binding sites and demonstration of decreased numbers of sites in obese rats. Metabolism. 1976 Feb; 25(2):179-91. PMID: 2834.
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    520. Reaven GM, Bernstein R, Davis B, Olefsky JM. Nonketotic diabetes mellitus: insulin deficiency or insulin resistance? Am J Med. 1976 Jan; 60(1):80-8. PMID: 814810.
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    521. Olefsky JM, Reaven GM. Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients. Am J Med. 1976 Jan; 60(1):89-95. PMID: 175653.
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    522. Olefsky JM. Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest. 1975 Dec; 56(6):1499-1508. PMID: 1202081.
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    523. Olefsky J, Johnson J, Liu F, Edwards P, Baur S. Comparison of 125-I-insulin binding and degradation to isolated rat hepatocytes and liver membranes. Diabetes. 1975 Sep; 24(9):801-10. PMID: 169175.
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    524. Olefsky JM, Reaven GM. Effects of age and obesity on insulin binding to isolated adipocytes. Endocrinology. 1975 Jun; 96(6):1486-98. PMID: 165063.
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    525. Peterson VE, Crapo PA, Weininger J, Ginsberg H, Olefsky J. Quantification of plasma cholesterol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements. Am J Clin Nutr. 1975 Jun; 28(6):584-7. PMID: 165703.
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    526. Olefsky JM, Johnson J, Liu F, Jen P, Reaven GM. The effects of acute and chronic dexamethasone administration on insulin binding to isolated rat hepatocytes and adipocytes. Metabolism. 1975 Apr; 24(4):517-27. PMID: 1117842.
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    527. Olefsky J, Crapo PA, Ginsberg H, Reaven GM. Metabolic effects of increased caloric intake in man. Metabolism. 1975 Apr; 24(4):495-503. PMID: 1117841.
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    528. Ginsberg H, Olefsky JM, Reaven GM. Evaluation of insulin resistance in patients with primary hyperparathyroidism. Proc Soc Exp Biol Med. 1975 Mar; 148(3):942-5. PMID: 1129318.
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    529. Ginsberg H, Kimmerling G, Olefsky JM, Reaven GM. Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia. J Clin Invest. 1975 Mar; 55(3):454-61. PMID: 1117064.
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    530. Mondon CE, Olefsky JM, Dolkas CB, Reaven GM. Removal of insulin by perfused rat liver: effect of concentration. Metabolism. 1975 Feb; 24(2):153-60. PMID: 1113679.
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    531. Mondon CE, Dolkas CB, Olefsky JM, Reaven GM. Insulin sensitivity of isolated perfused rat liver. Diabetes. 1975 Feb; 24(2):225-9. PMID: 1123110.
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    532. Olefsky JM, Reaven GM. Decreased insulin binding to lymphocytes from diabetic subjects. J Clin Invest. 1974 Dec; 54(6):1323-8. PMID: 4474186.
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    533. Olefsky JM, Farquhar JW, Reaven GM. Reappraisal of the role of insulin in hypertriglyceridemia. Am J Med. 1974 Oct; 57(4):551-60. PMID: 4372881.
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    534. Ginsberg H, Olefsky JM, Reaven GM. Further evidence that insulin resistance exists in patients with chemical diabetes. Diabetes. 1974 Aug; 23(8):674-8. PMID: 4852112.
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    535. Olefsky JM, Jen P, Reaven GM, Alto P. Insulin binding to isolated human adipocytes. Diabetes. 1974 Jul; 23(7):565-71. PMID: 4366488.
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    536. Olefsky JM, Batchelder T, Colome S, Reaven GM. Effect of intravenous glucose infusion on plasma insulin removal rate. Metabolism. 1974 Jun; 23(6):543-8. PMID: 4828443.
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    537. Olefsky JM, Reaven GM. Insulin and glucose responses to identical oral glucose tolerance tests performed forty-eight hours apart. Diabetes. 1974 May; 23(5):449-53. PMID: 4830180.
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    538. Reaven GM, Olefsky JM. Relationship between insulin response during the intravenous glucose tolerance test, rate of fractional glucose removal and the degree of insulin resistance in normal adults. Diabetes. 1974 May; 23(5):454-9. PMID: 4830181.
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    539. Olefsky J, Reaven GM. The human lymphocyte: a model for the study of insulin-receptor interaction. J Clin Endocrinol Metab. 1974 Apr; 38(4):554-60. PMID: 4362393.
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    540. Olefsky J, Farquhar JW, Reaven GM. Sex difference in the kinetics of triglyceride metabolism in normal and hypertriglyceridaemic human subjects. Eur J Clin Invest. 1974 Apr; 4(2):121-27. PMID: 4365003.
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    541. Ginsberg H, Olefsky J, Farquhar JW, Reaven GM. Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceridemic persons. Ann Intern Med. 1974 Feb; 80(2):143-9. PMID: 4359737.
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    542. Reaven GM, Olefsky JM. Increased plasma glucose and insulin responses to high-carbohydrate feedings in normal subjects. J Clin Endocrinol Metab. 1974 Jan; 38(1):151-4. PMID: 4809638.
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    543. Olefsky J, Reaven GM, Farquhar JW. Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects. J Clin Invest. 1974 Jan; 53(1):64-76. PMID: 4357617.
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    544. Olefsky J, Batchelder T, Farquhar JW, Reaven GM. Disassociation of the plasma insulin response from the blood glucose concentration during glucose infusions in normal dogs. Metabolism. 1973 Oct; 22(10):1277-86. PMID: 4784528.
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    545. Stern MP, Olefsky J, Farquhar JW, Reaven GM. Relationship between fasting plasma lipid levels and adipose tissue morphology. Metabolism. 1973 Oct; 22(10):1311-7. PMID: 4784530.
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    546. Olefsky J, Farquhar JW, Reaven G. Relationship between fasting plasma insulin level and resistance to insulin-mediated glucose uptake in normal and diabetic subjects. Diabetes. 1973 Jul; 22(7):507-13. PMID: 4719190.
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    547. Olefsky JM, Farquhar JW, Reaven GM. Do the oral and intravenous glucose tolerance tests provide similar diagnostic information in patients with chemical diabetes mellitus? Diabetes. 1973 Mar; 22(3):202-9. PMID: 4689294.
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    548. Reaven GM, Olefsky J, Farquhar JW. Does hyperglycaemia or hyperinsulinaemia characterise the patient with chemical diabetes? Lancet. 1972 Jun 10; 1(7763):1247-9. PMID: 4113513.
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    549. Olefsky J, Kempson R, Jones H, Reaven G. "Tertiary" hyperparathyroidism and apparent "cure" of vitamin-D-resistant rickets after removal of an ossifying mesenchymal tumor of the pharynx. N Engl J Med. 1972 Apr 06; 286(14):740-5. PMID: 4337228.
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