Natasha Martin
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Title(s) | Associate Professor, Medicine |
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School | Vc-health Sciences-schools |
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Address | 9500 Gilman Drive # La Jolla CA 92093
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vCard | Download vCard |
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Biography Oxford University, Oxford, UK | DPhil/PhD | 2009 | Mathematical biology | Stanford University, Palo Alto, CA | BS | 2003 | Mathematics, biology |
| 2016 | | Selected by The Economist Magazine as an "HCV Changemaker" |
Overview Dr. Natasha Martin is an infectious disease economic modeler who develops dynamic transmission models to evaluate the impact and cost-effectiveness of public health interventions. She is currently an Associate Professor in the Division of Infectious Diseases and Global Public Health at the University of California San Diego and holds an honorary senior lecturer position at the University of Bristol. She is also the co-director of the Biostatistics and Modeling Core of the University of California San Diego Center for AIDS Research (UCSD CFAR). She has worked for 18 years developing mathematical models of disease progression and transmission in both communicable and non-communicable diseases. For the past eight years, her primary research has focused on modeling hepatitis C virus (HCV) and HIV transmission and prevention among high-risk groups such as people who inject drugs (PWID), men who have sex with men, and female sex workers. She is a leading researcher on modeling the impact of HCV treatment as prevention. Additionally, she has experience developing dynamic cost-effectiveness evaluations of case-finding and prevention interventions, and has the only published cost-effectiveness models of HCV case-finding interventions and treatment including both individual and population benefits. She is the principal investigator (PI) of a NIAID/NIDA-funded R01 optimizing HIV and HCV prevention portfolios among people who inject drugs in 108 countries. Her modeling work informed the WHO guidelines “When to start ART in people living with HIV (2013)”, and her work on the impact and cost-effectiveness of HCV treatment among people who inject drugs informed the WHO guidelines on “Hepatitis C testing, care, and treatment (2013)”. More recently, her modeling work on HCV elimination was used to inform the WHO “Global Health Sector Strategy on Viral Hepatitis 2016-2021”.
Research ORNG Applications Bibliographic
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Scaling Up Hepatitis C Prevention and Treatment Interventions for Achieving Elimination in the United States: A Rural and Urban Comparison. Am J Epidemiol. 2019 08 01; 188(8):1539-1551.
Fraser H, Vellozzi C, Hoerger TJ, Evans JL, Kral AH, Havens J, Young AM, Stone J, Handanagic S, Hariri S, Barbosa C, Hickman M, Leib A, Martin NK, Nerlander L, Raymond HF, Page K, Zibbell J, Ward JW, Vickerman P. PMID: 31150044.
View in: PubMed Mentions: 8 Fields: Translation: Humans
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Cost-effectiveness and budgetary impact of HCV treatment with direct-acting antivirals in India including the risk of reinfection. PLoS One. 2019; 14(6):e0217964.
Chaillon A, Mehta SR, Hoenigl M, Solomon SS, Vickerman P, Hickman M, Skaathun B, Martin NK. PMID: 31170246.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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The contribution of injection drug use to hepatitis C virus transmission globally, regionally, and at country level: a modelling study. Lancet Gastroenterol Hepatol. 2019 06; 4(6):435-444.
Trickey A, Fraser H, Lim AG, Peacock A, Colledge S, Walker JG, Leung J, Grebely J, Larney S, Martin NK, Hickman M, Degenhardt L, May MT, Vickerman P. PMID: 30981685.
View in: PubMed Mentions: 10 Fields: Translation: Humans
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Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015. Open Forum Infect Dis. 2019 Apr; 6(4):ofz160.
Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK. PMID: 31041355.
View in: PubMed Mentions:
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A matched comparison study of hepatitis C treatment outcomes in the prison and community setting, and an analysis of the impact of prison release or transfer during therapy. J Viral Hepat. 2016 12; 23(12):1009-1016.
Aspinall EJ, Mitchell W, Schofield J, Cairns A, Lamond S, Bramley P, Peters SE, Valerio H, Tomnay J, Goldberg DJ, Mills PR, Barclay ST, Fraser A, Dillon JF, Martin NK, Hickman M, Hutchinson SJ. PMID: 27509844.
View in: PubMed Mentions: 13 Fields: Translation: Humans
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New treatments for hepatitis C virus (HCV): scope for preventing liver disease and HCV transmission in England. J Viral Hepat. 2016 08; 23(8):631-43.
Harris RJ, Martin NK, Rand E, Mandal S, Mutimer D, Vickerman P, Ramsay ME, De Angelis D, Hickman M, Harris HE. PMID: 27025238.
View in: PubMed Mentions: 14 Fields: Translation: Humans
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HCV treatment rates and sustained viral response among people who inject drugs in seven UK sites: real world results and modelling of treatment impact. J Viral Hepat. 2015 Apr; 22(4):399-408.
Martin NK, Foster GR, Vilar J, Ryder S, Cramp ME, Gordon F, Dillon JF, Craine N, Busse H, Clements A, Hutchinson SJ, Ustianowski A, Ramsay M, Goldberg DJ, Irving W, Hope V, De Angelis D, Lyons M, Vickerman P, Hickman M. PMID: 25288193.
View in: PubMed Mentions: 34 Fields: Translation: HumansCells
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Assessing the cost-effectiveness of finding cases of hepatitis C infection in UK migrant populations and the value of further research. J Viral Hepat. 2014; 21(9):616-23.
Miners AH, Martin NK, Ghosh A, Hickman M, Vickerman P. PMID: 24215210.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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A general reaction-diffusion model of acidity in cancer invasion. J Math Biol. 2014 Apr; 68(5):1199-224.
McGillen JB, Gaffney EA, Martin NK, Maini PK. PMID: 23536240.
View in: PubMed Mentions: 2 Fields: Translation: HumansCells
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C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection. Eur J Gastroenterol Hepatol. 2013 Jan; 25(1):33-6.
Farne HA, Martin NK, Main J, Orchard T, Tyrrell-Price J. PMID: 23026925.
View in: PubMed Mentions: 1 Fields: Translation: HumansCells
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Could low dead-space syringes really reduce HIV transmission to low levels? Int J Drug Policy. 2013 Jan; 24(1):8-14.
Vickerman P, Martin NK, Hickman M. PMID: 23206493.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimalsPHPublic Health
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Pancreatic insufficiency in patients with HIV infection: role of didanosine questioned. HIV Med. 2013 Mar; 14(3):161-6.
Martin TC, Scourfield A, Rockwood N, Martin NK, Patel N, Nelson M, Gazzard BG. PMID: 22994793.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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Predicting the safety and efficacy of buffer therapy to raise tumour pHe: an integrative modelling study. Br J Cancer. 2012 Mar 27; 106(7):1280-7.
Martin NK, Robey IF, Gaffney EA, Gillies RJ, Gatenby RA, Maini PK. PMID: 22382688.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimals
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Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer. BMC Cancer. 2011 Jun 10; 11:235.
Robey IF, Martin NK. PMID: 21663677.
View in: PubMed Mentions: 21 Fields: Translation: HumansAnimalsCells
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A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Math Biosci. 2011 Mar; 230(1):1-11.
Martin NK, Gaffney EA, Gatenby RA, Gillies RJ, Robey IF, Maini PK. PMID: 21167185.
View in: PubMed Mentions: 15 Fields: Translation: HumansAnimalsCells
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Tumour-stromal interactions in acid-mediated invasion: a mathematical model. J Theor Biol. 2010 Dec 07; 267(3):461-70.
Martin NK, Gaffney EA, Gatenby RA, Maini PK. PMID: 20816684.
View in: PubMed Mentions: 16 Fields: Translation: HumansAnimalsCells
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Leaky vessels as a potential source of stromal acidification in tumours. J Theor Biol. 2010 Dec 07; 267(3):454-60.
Martin NK, Gaffney EA, Gatenby RA, Maini PK. PMID: 20699102.
View in: PubMed Mentions: 1 Fields: Translation: HumansAnimals
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Year | Publications |
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2010 | 3 | 2011 | 1 | 2012 | 3 | 2013 | 3 | 2014 | 1 | 2016 | 2 | 2019 | 4 |
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