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    Alfredo Molinolo

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentPathology
    Address9500 Gilman Drive #0819
    CA La Jolla 92093
    Phone858-246-0179
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      Collapse Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Rey S, Quintavalle C, Burmeister K, Calabrese D, Schlageter M, Quagliata L, Cathomas G, Diebold J, Molinolo A, Heim MH, Terracciano LM, Matter MS. Liver damage and senescence increases in patients developing hepatocellular carcinoma. J Gastroenterol Hepatol. 2017 Aug; 32(8):1480-1486. PMID: 28052383.
        View in: PubMed
      2. Khurana A, Chapelin F, Xu H, Acevedo JR, Molinolo A, Nguyen Q, Ahrens ET. Visualization of macrophage recruitment in head and neck carcinoma model using fluorine-19 magnetic resonance imaging. Magn Reson Med. 2017 Jul 26. PMID: 28748562.
        View in: PubMed
      3. Rojas PA, May M, Sequeira GR, Elia A, Alvarez M, Martínez P, Gonzalez P, Hewitt S, He X, Perou CM, Molinolo A, Gibbons L, Abba MC, Gass H, Lanari C. Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness. J Natl Cancer Inst. 2017 07 01; 109(7). PMID: 28376177.
        View in: PubMed
      4. Hingorani DV, Lemieux AJ, Acevedo JR, Glasgow HL, Kedarisetty S, Whitney MA, Molinolo A, Tsien RY, Nguyen QT. Early detection of squamous cell carcinoma in carcinogen induced oral cancer rodent model by ratiometric activatable cell penetrating peptides. Oral Oncol. 2017 Aug; 71:156-162. PMID: 28688684.
        View in: PubMed
      5. Doçi CL, Mikelis CM, Callejas-Valera JL, Hansen KK, Molinolo A, Inoue A, Offermanns S, Gutkind JS. Epidermal loss of Gaq confers a migratory and differentiation defect in keratinocytes. PLoS One. 2017; 12(3):e0173692. PMID: 28301547.
        View in: PubMed
      6. Ramnitz MS, Gourh P, Goldbach-Mansky R, Wodajo F, Ichikawa S, Econs MJ, White KE, Molinolo A, Chen MY, Heller T, Del Rivero J, Seo-Mayer P, Arabshahi B, Jackson MB, Hatab S, McCarthy E, Guthrie LC, Brillante BA, Gafni RI, Collins MT. Phenotypic and Genotypic Characterization and Treatment of a Cohort With Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome. J Bone Miner Res. 2016 Oct; 31(10):1845-1854. PMID: 27164190.
        View in: PubMed
      7. Callejas-Valera JL, Iglesias-Bartolome R, Amornphimoltham P, Palacios-Garcia J, Martin D, Califano JA, Molinolo A, Gutkind JS. mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model. Carcinogenesis. 2016 Oct; 37(10):1014-25. PMID: 27538837.
        View in: PubMed
      8. Fadlullah MZ, Chiang IK, Dionne KR, Yee PS, Gan CP, Sam KK, Tiong KH, Ng AK, Martin D, Lim KP, Kallarakkal TG, Mustafa WM, Lau SH, Abraham MT, Zain RB, Rahman ZA, Molinolo A, Patel V, Gutkind JS, Tan AC, Cheong SC. Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies. Oncotarget. 2016 May 10; 7(19):27802-18. PMID: 27050151.
        View in: PubMed
      9. Matter MS, Marquardt JU, Andersen JB, Quintavalle C, Korokhov N, Stauffer JK, Kaji K, Decaens T, Quagliata L, Elloumi F, Hoang T, Molinolo A, Conner EA, Weber A, Heikenwalder M, Factor VM, Thorgeirsson SS. Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. Hepatology. 2016 Jun; 63(6):1888-99. PMID: 26844528; PMCID: PMC4874846 [Available on 06/01/17].
        View in: PubMed, PubMed Central
      10. Yamaguchi K, Iglesias-Bartolomé R, Wang Z, Callejas-Valera JL, Amornphimoltham P, Molinolo A, Cohen EE, Califano JA, Lippman SM, Luo J, Gutkind JS. A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers. Oncotarget. 2016 Mar 08; 7(10):10696-709. PMID: 26882569; PMCID: PMC4905432.
        View in: PubMed, PubMed Central
      11. O'Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis CM, Drummond RA, Avino S, Finkel K, Kalim KW, DiPasquale G, Guo F, Aoki J, Zheng Y, Lionakis MS, Molinolo A, Gutkind JS. Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Ga13/RhoA axis in B cells. Oncogene. 2016 Jul 21; 35(29):3771-80. PMID: 26616858; PMCID: PMC4885800.
        View in: PubMed, PubMed Central
      12. May M, Mosto J, Vazquez PM, Gonzalez P, Rojas P, Gass H, Lanari C, Molinolo A. Nuclear staining of fgfr-2/stat-5 and runx-2 in mucinous breast cancer. Exp Mol Pathol. 2016 Feb; 100(1):39-44. PMID: 26551078.
        View in: PubMed
      13. Yoneda M, Molinolo A, Ward JM, Kimura S, Goodlad RA. A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine. J Vis Exp. 2015 Oct 27; (105):e53042. PMID: 26556642.
        View in: PubMed
      14. Milenic DE, Molinolo A, Solivella MS, Banaga E, Torgue J, Besnainou S, Brechbiel MW, Baidoo KE. Toxicological Studies of 212Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial. Pharmaceuticals (Basel). 2015 Jul 24; 8(3):416-34. PMID: 26213947; PMCID: PMC4588175.
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      15. Iglesias-Bartolome R, Torres D, Marone R, Feng X, Martin D, Simaan M, Chen M, Weinstein LS, Taylor SS, Molinolo A, Gutkind JS. Inactivation of a Ga(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015 Jun; 17(6):793-803. PMID: 25961504; PMCID: PMC4449815.
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      16. Doçi CL, Mikelis CM, Lionakis MS, Molinolo A, Gutkind JS. Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma. Cancer Res. 2015 Jul 15; 75(14):2937-48. PMID: 25952650; PMCID: PMC4538958.
        View in: PubMed, PubMed Central
      17. Zoratti GL, Tanabe LM, Varela FA, Murray AS, Bergum C, Colombo É, Lang JE, Molinolo A, Leduc R, Marsault E, Boerner J, List K. Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. Nat Commun. 2015 Apr 15; 6:6776. PMID: 25873032; PMCID: PMC4749267.
        View in: PubMed, PubMed Central
      18. Madera D, Vitale-Cross L, Martin D, Schneider A, Molinolo A, Gangane N, Carey TE, McHugh JB, Komarck CM, Walline HM, William WN, Seethala RR, Ferris RL, Gutkind JS. Prevention of tumor growth driven by PIK3CA and HPV oncogenes by targeting mTOR signaling with metformin in oral squamous carcinomas expressing OCT3. Cancer Prev Res (Phila). 2015 Mar; 8(3):197-207. PMID: 25681087; PMCID: PMC4355306.
        View in: PubMed, PubMed Central
      19. Dillenburg-Pilla P, Patel V, Mikelis CM, Zárate-Bladés CR, Doçi CL, Amornphimoltham P, Wang Z, Martin D, Leelahavanichkul K, Dorsam RT, Masedunskas A, Weigert R, Molinolo A, Gutkind JS. SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gai/mTORC1 axis. FASEB J. 2015 Mar; 29(3):1056-68. PMID: 25466898; PMCID: PMC4422355.
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      20. Williams KA, Lee M, Hu Y, Andreas J, Patel SJ, Zhang S, Chines P, Elkahloun A, Chandrasekharappa S, Gutkind JS, Molinolo A, Crawford NP. A systems genetics approach identifies CXCL14, ITGAX, and LPCAT2 as novel aggressive prostate cancer susceptibility genes. PLoS Genet. 2014 Nov; 10(11):e1004809. PMID: 25411967; PMCID: PMC4238980.
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      21. Wargon V, Riggio M, Giulianelli S, Sequeira GR, Rojas P, May M, Polo ML, Gorostiaga MA, Jacobsen B, Molinolo A, Novaro V, Lanari C. Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters. Int J Cancer. 2015 Jun 01; 136(11):2680-92. PMID: 25363551; PMCID: PMC4361264.
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      22. Gan CP, Patel V, Mikelis CM, Zain RB, Molinolo A, Abraham MT, Teo SH, Abdul Rahman ZA, Gutkind JS, Cheong SC. Heterotrimeric G-protein alpha-12 (Ga12) subunit promotes oral cancer metastasis. Oncotarget. 2014 Oct 30; 5(20):9626-40. PMID: 25275299; PMCID: PMC4259425.
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      23. Martin D, Abba MC, Molinolo A, Vitale-Cross L, Wang Z, Zaida M, Delic NC, Samuels Y, Lyons JG, Gutkind JS. The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies. Oncotarget. 2014 Oct 15; 5(19):8906-23. PMID: 25275298; PMCID: PMC4253406.
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      24. Smith JP, Cooper TK, McGovern CO, Gilius EL, Zhong Q, Liao J, Molinolo A, Gutkind JS, Matters GL. Cholecystokinin receptor antagonist halts progression of pancreatic cancer precursor lesions and fibrosis in mice. Pancreas. 2014 Oct; 43(7):1050-9. PMID: 25058882; PMCID: PMC4161619.
        View in: PubMed, PubMed Central
      25. Wang Z, Martin D, Molinolo A, Patel V, Iglesias-Bartolome R, Degese MS, Vitale-Cross L, Chen Q, Gutkind JS. mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations. J Natl Cancer Inst. 2014 Sep; 106(9). PMID: 25099740; PMCID: PMC4133928.
        View in: PubMed, PubMed Central
      26. Farsaci B, Donahue RN, Coplin MA, Grenga I, Lepone LM, Molinolo A, Hodge JW. Immune consequences of decreasing tumor vasculature with antiangiogenic tyrosine kinase inhibitors in combination with therapeutic vaccines. Cancer Immunol Res. 2014 Nov; 2(11):1090-102. PMID: 25092771; PMCID: PMC4221465.
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      27. Madsen DH, Szabo R, Molinolo A, Bugge TH. TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition. Biochem J. 2014 Aug 01; 461(3):487-95. PMID: 24832573; PMCID: PMC4625982.
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      28. Peters DE, Hoover B, Cloud LG, Liu S, Molinolo A, Leppla SH, Bugge TH. Comparative toxicity and efficacy of engineered anthrax lethal toxin variants with broad anti-tumor activities. Toxicol Appl Pharmacol. 2014 Sep 01; 279(2):220-9. PMID: 24971906; PMCID: PMC4137396.
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      29. Sequeira G, Vanzulli SI, Rojas P, Lamb C, Colombo L, May M, Molinolo A, Lanari C. The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer. Oncotarget. 2014 May 30; 5(10):3246-60. PMID: 24912774; PMCID: PMC4102807.
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      30. Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo A, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry. Cancer Cell. 2014 Jun 16; 25(6):831-45. PMID: 24882515; PMCID: PMC4074519.
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      31. Wang HD, Boyce AM, Tsai JY, Gafni RI, Farley FA, Kasa-Vubu JZ, Molinolo A, Collins MT. Effects of denosumab treatment and discontinuation on human growth plates. J Clin Endocrinol Metab. 2014 Mar; 99(3):891-7. PMID: 24423331; PMCID: PMC3942242.
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      32. Simpson RM, Bastian BC, Michael HT, Webster JD, Prasad ML, Conway CM, Prieto VM, Gary JM, Goldschmidt MH, Esplin DG, Smedley RC, Piris A, Meuten DJ, Kiupel M, Lee CC, Ward JM, Dwyer JE, Davis BJ, Anver MR, Molinolo A, Hoover SB, Rodriguez-Canales J, Hewitt SM. Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma. Pigment Cell Melanoma Res. 2014 Jan; 27(1):37-47. PMID: 24128326; PMCID: PMC4066658.
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      33. Leelahavanichkul K, Amornphimoltham P, Molinolo A, Basile JR, Koontongkaew S, Gutkind JS. A role for p38 MAPK in head and neck cancer cell growth and tumor-induced angiogenesis and lymphangiogenesis. Mol Oncol. 2014 Feb; 8(1):105-18. PMID: 24216180; PMCID: PMC3946852.
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      34. Ono M, Inkson CA, Sonn R, Kilts TM, de Castro LF, Maeda A, Fisher LW, Robey PG, Berendsen AD, Li L, McCartney-Francis N, Brown AC, Crawford NP, Molinolo A, Jain A, Fedarko NS, Young MF. WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone. PLoS One. 2013; 8(8):e71709. PMID: 23977121; PMCID: PMC3743748.
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      35. Coppock JD, Wieking BG, Molinolo A, Gutkind JS, Miskimins WK, Lee JH. Improved clearance during treatment of HPV-positive head and neck cancer through mTOR inhibition. Neoplasia. 2013 Jun; 15(6):620-30. PMID: 23730210; PMCID: PMC3664994.
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      36. Martin D, Nguyen Q, Molinolo A, Gutkind JS. Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene. Oncogene. 2014 May 01; 33(18):2405-12. PMID: 23708663.
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      37. Sahores A, Luque GM, Wargon V, May M, Molinolo A, Becu-Villalobos D, Lanari C, Lamb CA. Novel, low cost, highly effective, handmade steroid pellets for experimental studies. PLoS One. 2013; 8(5):e64049. PMID: 23691144; PMCID: PMC3655057.
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      38. Squarize CH, Castilho RM, Abrahao AC, Molinolo A, Lingen MW, Gutkind JS. PTEN deficiency contributes to the development and progression of head and neck cancer. Neoplasia. 2013 May; 15(5):461-71. PMID: 23633918; PMCID: PMC3638349.
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      39. Patel SJ, Molinolo A, Gutkind S, Crawford NP. Germline genetic variation modulates tumor progression and metastasis in a mouse model of neuroendocrine prostate carcinoma. PLoS One. 2013; 8(4):e61848. PMID: 23620793; PMCID: PMC3631138.
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      40. Amornphimoltham P, Rechache K, Thompson J, Masedunskas A, Leelahavanichkul K, Patel V, Molinolo A, Gutkind JS, Weigert R. Rab25 regulates invasion and metastasis in head and neck cancer. Clin Cancer Res. 2013 Mar 15; 19(6):1375-88. PMID: 23340300; PMCID: PMC3602237.
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      41. Giulianelli S, Molinolo A, Lanari C. Targeting progesterone receptors in breast cancer. Vitam Horm. 2013; 93:161-84. PMID: 23810006.
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      42. Patel V, Martin D, Malhotra R, Marsh CA, Doçi CL, Veenstra TD, Nathan CA, Sinha UK, Singh B, Molinolo A, Rusling JF, Gutkind JS. DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays. Oral Oncol. 2013 Feb; 49(2):93-101. PMID: 23010602; PMCID: PMC3546158.
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      43. Iglesias-Bartolome R, Patel V, Cotrim A, Leelahavanichkul K, Molinolo A, Mitchell JB, Gutkind JS. mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis. Cell Stem Cell. 2012 Sep 07; 11(3):401-14. PMID: 22958932; PMCID: PMC3477550.
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      44. Rudmann D, Cardiff R, Chouinard L, Goodman D, Küttler K, Marxfeld H, Molinolo A, Treumann S, Yoshizawa K. Proliferative and nonproliferative lesions of the rat and mouse mammary, Zymbal's, preputial, and clitoral glands. Toxicol Pathol. 2012 Aug; 40(6 Suppl):7S-39S. PMID: 22949413.
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      45. Tamburrino A, Molinolo A, Salerno P, Chernock RD, Raffeld M, Xi L, Gutkind JS, Moley JF, Wells SA, Santoro M. Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases. Clin Cancer Res. 2012 Jul 01; 18(13):3532-40. PMID: 22753663.
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      46. Boyce AM, Chong WH, Yao J, Gafni RI, Kelly MH, Chamberlain CE, Bassim C, Cherman N, Ellsworth M, Kasa-Vubu JZ, Farley FA, Molinolo A, Bhattacharyya N, Collins MT. Denosumab treatment for fibrous dysplasia. J Bone Miner Res. 2012 Jul; 27(7):1462-70. PMID: 22431375; PMCID: PMC3377825.
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      47. Gandini NA, Fermento ME, Salomón DG, Blasco J, Patel V, Gutkind JS, Molinolo A, Facchinetti MM, Curino AC. Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas. Exp Mol Pathol. 2012 Oct; 93(2):237-45. PMID: 22580187.
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      48. Peters DE, Zhang Y, Molinolo A, Miller-Randolph S, Szabo R, Bugge TH, Leppla SH, Liu S. Capillary morphogenesis protein-2 is required for mouse parturition by maintaining uterine collagen homeostasis. Biochem Biophys Res Commun. 2012 Jun 08; 422(3):393-7. PMID: 22575514; PMCID: PMC3376708.
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      49. Lanari C, Wargon V, Rojas P, Molinolo A. Antiprogestins in breast cancer treatment: are we ready? Endocr Relat Cancer. 2012 Jun; 19(3):R35-50. PMID: 22351709.
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      50. Vitale-Cross L, Molinolo A, Martin D, Younis RH, Maruyama T, Patel V, Chen W, Schneider A, Gutkind JS. Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions. Cancer Prev Res (Phila). 2012 Apr; 5(4):562-73. PMID: 22467081; PMCID: PMC3429367.
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      51. Degese MS, Mendizabal JE, Gandini NA, Gutkind JS, Molinolo A, Hewitt SM, Curino AC, Coso OA, Facchinetti MM. Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data. Lung Cancer. 2012 Jul; 77(1):168-75. PMID: 22418244.
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      52. Molinolo A, Marsh C, El Dinali M, Gangane N, Jennison K, Hewitt S, Patel V, Seiwert TY, Gutkind JS. mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas. Clin Cancer Res. 2012 May 01; 18(9):2558-68. PMID: 22409888; PMCID: PMC3443560.
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      53. Giulianelli S, Vaqué JP, Soldati R, Wargon V, Vanzulli SI, Martins R, Zeitlin E, Molinolo A, Helguero LA, Lamb CA, Gutkind JS, Lanari C. Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters. Cancer Res. 2012 May 01; 72(9):2416-27. PMID: 22396492.
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      54. Wise-Draper TM, Draper DJ, Gutkind JS, Molinolo A, Wikenheiser-Brokamp KA, Wells SI. Future directions and treatment strategies for head and neck squamous cell carcinomas. Transl Res. 2012 Sep; 160(3):167-77. PMID: 22683420; PMCID: PMC3423575.
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      55. Giulianelli S, Vaqué JP, Wargon V, Soldati R, Vanzulli SI, Martins R, Zeitlin E, Helguero L, Lamb C, Molinolo A, Gutkind JS, Lanari C. [The role of estrogen receptor alpha in breast cancer cell proliferation mediated by progestins]. Medicina (B Aires). 2012; 72(4):315-20. PMID: 22892083.
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      56. Kosa P, Szabo R, Molinolo A, Bugge TH. Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis. Oncogene. 2012 Aug 09; 31(32):3679-95. PMID: 22139080; PMCID: PMC3299858.
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      57. Cerliani JP, Vanzulli SI, Piñero CP, Bottino MC, Sahores A, Nuñez M, Varchetta R, Martins R, Zeitlin E, Hewitt SM, Molinolo A, Lanari C, Lamb CA. Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer. Breast Cancer Res Treat. 2012 Jun; 133(3):997-1008. PMID: 22124578.
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      58. Bian Y, Hall B, Sun ZJ, Molinolo A, Chen W, Gutkind JS, Waes CV, Kulkarni AB. Loss of TGF-ß signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation. Oncogene. 2012 Jul 12; 31(28):3322-32. PMID: 22037217; PMCID: PMC3270146.
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      59. Patel V, Marsh CA, Dorsam RT, Mikelis CM, Masedunskas A, Amornphimoltham P, Nathan CA, Nathan CA, Singh B, Weigert R, Molinolo A, Gutkind JS. Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer. Cancer Res. 2011 Nov 15; 71(22):7103-12. PMID: 21975930; PMCID: PMC3443559.
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      60. Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y. Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet. 2011 Sep 25; 43(11):1119-26. PMID: 21946352; PMCID: PMC3376644.
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      61. Yagi H, Tan W, Dillenburg-Pilla P, Armando S, Amornphimoltham P, Simaan M, Weigert R, Molinolo A, Bouvier M, Gutkind JS. A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells. Sci Signal. 2011 Sep 20; 4(191):ra60. PMID: 21934106; PMCID: PMC3429372.
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      62. Sales KU, Hobson JP, Wagenaar-Miller R, Szabo R, Rasmussen AL, Bey A, Shah MF, Molinolo A, Bugge TH. Expression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HAT. PLoS One. 2011; 6(8):e23261. PMID: 21853097; PMCID: PMC3154331.
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      63. Martin D, Galisteo R, Molinolo A, Wetzker R, Hirsch E, Gutkind JS. PI3K? mediates kaposi's sarcoma-associated herpesvirus vGPCR-induced sarcomagenesis. Cancer Cell. 2011 Jun 14; 19(6):805-13. PMID: 21665152; PMCID: PMC3170773.
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      64. Chong WH, Molinolo A, Chen CC, Collins MT. Tumor-induced osteomalacia. Endocr Relat Cancer. 2011 Jun; 18(3):R53-77. PMID: 21490240; PMCID: PMC3433741.
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      65. Schafer JM, Peters DE, Morley T, Liu S, Molinolo A, Leppla SH, Bugge TH. Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin. PLoS One. 2011; 6(5):e20532. PMID: 21655226; PMCID: PMC3105081.
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      66. Szabo R, Rasmussen AL, Moyer AB, Kosa P, Schafer JM, Molinolo A, Gutkind JS, Bugge TH. c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase. Oncogene. 2011 Apr 28; 30(17):2003-16. PMID: 21217780; PMCID: PMC3084339.
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      67. Patel V, Iglesias-Bartolome R, Siegele B, Marsh CA, Leelahavanichkul K, Molinolo A, Gutkind JS. Cellular systems for studying human oral squamous cell carcinomas. Adv Exp Med Biol. 2011; 720:27-38. PMID: 21901616.
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      68. Bhirde AA, Patel S, Sousa AA, Patel V, Molinolo A, Ji Y, Leapman RD, Gutkind JS, Rusling JF. Distribution and clearance of PEG-single-walled carbon nanotube cancer drug delivery vehicles in mice. Nanomedicine (Lond). 2010 Dec; 5(10):1535-46. PMID: 21143032; PMCID: PMC3175610.
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      69. Abrahao AC, Castilho RM, Squarize CH, Molinolo A, dos Santos-Pinto D, Gutkind JS. A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation. Oral Oncol. 2010 Dec; 46(12):880-7. PMID: 20951077; PMCID: PMC2991505.
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      70. Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, López-Otín C, Samuels Y. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res. 2010 Nov; 8(11):1513-25. PMID: 21047771; PMCID: PMC3058631.
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      71. Giulianelli S, Herschkowitz JI, Patel V, Lamb CA, Gutkind JS, Molinolo A, Perou CM, Lanari C. MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements. Breast Cancer Res Treat. 2011 Aug; 129(1):49-67. PMID: 20890655.
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      72. Ma T, Jham BC, Hu J, Friedman ER, Basile JR, Molinolo A, Sodhi A, Montaner S. Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14363-8. PMID: 20660728; PMCID: PMC2922606.
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      152. Kordon E, Lanari C, Molinolo A, Elizalde PV, Charreau EH, Dosne Pasqualini C. Estrogen inhibition of MPA-induced mouse mammary tumor transplants. Int J Cancer. 1991 Dec 02; 49(6):900-5. PMID: 1835715.
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      153. Lanari C, Molinolo A, Kordon E, Pasualini CD, Charreau EH. Progesterone receptors in estrogen-induced fibromatosis of guinea pigs. Cancer Lett. 1990 Jun 15; 51(3):235-45. PMID: 2350763.
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      154. Schlom J, Molinolo A, Simpson JF, Siler K, Roselli M, Hinkle G, Houchens DP, Colcher D. Advantage of dose fractionation in monoclonal antibody-targeted radioimmunotherapy. J Natl Cancer Inst. 1990 May 02; 82(9):763-71. PMID: 2182892.
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      155. Molinolo A, Simpson JF, Thor A, Schlom J. Enhanced tumor binding using immunohistochemical analyses by second generation anti-tumor-associated glycoprotein 72 monoclonal antibodies versus monoclonal antibody B72.3 in human tissue. Cancer Res. 1990 Feb 15; 50(4):1291-8. PMID: 2297774.
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      156. Lanari C, Kordon E, Molinolo A, Pasqualini CD, Charreau EH. Mammary adenocarcinomas induced by medroxyprogesterone acetate: hormone dependence and EGF receptors of BALB/c in vivo sublines. Int J Cancer. 1989 May 15; 43(5):845-50. PMID: 2523869.
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      157. Shrivastav S, Schlom J, Raubitschek A, Molinolo A, Simpson J, Hand PH. Studies concerning the effect of external irradiation on localization of radiolabeled monoclonal antibody B72.3 to human colon carcinoma xenografts. Int J Radiat Oncol Biol Phys. 1989 Mar; 16(3):721-9. PMID: 2921170.
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      158. Muraro R, Kuroki M, Wunderlich D, Poole DJ, Colcher D, Thor A, Greiner JW, Simpson JF, Molinolo A, Noguchi P. Generation and characterization of B72.3 second generation monoclonal antibodies reactive with the tumor-associated glycoprotein 72 antigen. Cancer Res. 1988 Aug 15; 48(16):4588-96. PMID: 3396010.
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      159. Molinolo A, Lanari C, Charreau EH, Sanjuan N, Pasqualini CD. Mouse mammary tumors induced by medroxyprogesterone acetate: immunohistochemistry and hormonal receptors. J Natl Cancer Inst. 1987 Dec; 79(6):1341-50. PMID: 2826865.
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      160. Lanari C, Molinolo A, Pasqualini CD. Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c female mice. Cancer Lett. 1986 Nov; 33(2):215-23. PMID: 2947675.
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      161. Lanari C, Molinolo A, Pasqualini CD. Inhibitory effect of medroxyprogesterone acetate on foreign body tumorigenesis in mice. J Natl Cancer Inst. 1986 Jul; 77(1):157-64. PMID: 3522997.
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      162. Molinolo A, Meiss RP, Leo P, Sens AI. Demonstration of cytokeratins by immunoperoxidase staining in prostatic tissue. J Urol. 1985 Nov; 134(5):1037-40. PMID: 2414467.
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      163. Jufe R, Molinolo A, Fefer SA, Meiss RP. Plasma cell granuloma of the bladder: a case report. J Urol. 1984 Jun; 131(6):1175-6. PMID: 6726924.
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