Bing Ren

Title(s)Professor, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 
    Collapse Overview
    Our laboratory is interested in understanding how the complex gene regulatory networks in mammalian cells control cellular proliferation and differentiation. The research is divided into two general areas: 1) the development of genomics and bioinformatics tools that allow genome wide identification of regulatory targets for transcription factors; and, 2) the application of these tools to the study of transcription factors that play critical roles in cancer.

    Research Focus Areas:

  • Genetics and Genomics

  • Gene Expression and Regulation

  • Signal Transduction


    • Collapse Research 
    Collapse Research Activities and Funding
    High-throughput Single Cell Co-assay of Histone Modifications and Transcriptome
    NIH R41GM146330Sep 15, 2021 - Aug 31, 2022
    Role: Principal Investigator
    Ultra-high Throughout Single Cell Multi-omic Analysis of Histone Modifications and Transcriptome in Mouse and Human Brains
    NIH RF1MH128838Sep 13, 2021 - Sep 12, 2024
    Role: Principal Investigator
    The impact of genomic variation on environment-induced changes in pancreatic beta cell states
    NIH U01HG012059Sep 7, 2021 - May 31, 2026
    Role: Co-Principal Investigator
    Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models
    NIH R24AG073198Sep 1, 2021 - May 31, 2025
    Role: Co-Principal Investigator
    Unraveling the molecular pathology of retinal degeneration through single cell genomics
    NIH R01EY031663Jun 1, 2021 - May 31, 2026
    Role: Co-Principal Investigator
    Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus
    NIH U01DA052769Sep 30, 2020 - Aug 31, 2025
    Role: Co-Principal Investigator
    Center for Integrated Multi-modal and Multi-scale Nucleome Research
    NIH UM1HG011585Sep 24, 2020 - Jun 30, 2025
    Role: Principal Investigator
    Large scale discovery and validation of brain cell type enhancers for viral targeting and circuit manipulation
    NIH RF1MH124612Sep 23, 2020 - Sep 22, 2023
    Role: Co-Principal Investigator
    Multi-omic Brain Cell Atlas of Alzheimer's Disease Progression
    NIH R56AG069107Sep 17, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Epigenomic analysis of neural circuits in Alzheimer's disease mouse models
    NIH R01AG067153Apr 15, 2020 - Mar 31, 2025
    Role: Co-Principal Investigator
    Epigenome-based Cell Census and Regulatory Element Discovery in the Aging Mouse Brain
    NIH R01AG066018Sep 30, 2019 - Jun 30, 2024
    Role: Co-Principal Investigator
    High throughput CRISPR-mediated functional validation of regulatory elements
    NIH UM1HG009402Feb 1, 2017 - Jan 31, 2022
    Role: Principal Investigator
    San Diego Center for 4D Nucleome Research
    NIH U54DK107977Sep 30, 2015 - Jul 31, 2021
    Role: Principal Investigator
    The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub
    NIH U01CA200147Sep 1, 2015 - Aug 31, 2025
    Role: Principal Investigator
    Non-coding Variants Predisposing to Age-related Macular Degeneration
    NIH R01HG008135Aug 24, 2015 - Jun 30, 2019
    Role: Principal Investigator
    Functional Analysis of T2D Associated Non-coding SNPs
    NIH U01DK105541May 1, 2015 - Apr 30, 2020
    Role: Principal Investigator
    Integrative Analysis of Haplotype-Resolved Human Epigenome Maps
    NIH R01ES024984Sep 8, 2014 - Aug 31, 2017
    Role: Principal Investigator
    Center for Mammalian Regulatory Genomics
    NIH U54HG006997Sep 21, 2012 - Jul 31, 2018
    Role: Principal Investigator
    The San Diego Epigenome Center
    NIH U01ES017166Sep 29, 2008 - Jun 30, 2014
    Role: Principal Investigator
    Genome-wide map of active promoters in the mouse cells
    NIH R01HG003991Sep 18, 2008 - Jul 31, 2012
    Role: Principal Investigator
    TRANSCRIPTION FACTOR TARGET MAPPING IN MAMMALIAN GENOME
    NIH R33CA105829Aug 16, 2004 - Oct 31, 2008
    Role: Principal Investigator
    TRANSCRIPTION FACTOR TARGET MAPPING IN MAMMALIAN GENOME
    NIH R21CA105829Aug 16, 2004 - Jul 31, 2005
    Role: Principal Investigator
    Mapping transcriptional regulatory elements in human DNA
    NIH U01HG003151Sep 30, 2003 - Sep 30, 2008
    Role: Principal Investigator
    Graduate Training Program in Bioinformatics
    NIH T32GM008806Jul 1, 2001 - Jun 30, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Efficient, scalable, and near-nucleotide-resolution profiling of protein occupancy in the genome with deaminases. Proc Natl Acad Sci U S A. 2025 Feb 04; 122(5):e2425203122. Chang L, Ren B. PMID: 39869813; PMCID: PMC11804588.
      View in: PubMed   Mentions:    Fields:    
    2. Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease. J Hepatol. 2024 Nov 08. Kim HY, Rosenthal SB, Liu X, Miciano C, Hou X, Miller M, Buchanan J, Poirion OB, Chilin-Fuentes D, Han C, Housseini M, Carvalho-Gontijo Weber R, Sakane S, Lee W, Zhao H, Diggle K, Preissl S, Glass CK, Ren B, Wang A, Brenner DA, Kisseleva T. PMID: 39522884.
      View in: PubMed   Mentions:    Fields:    
    3. Emerging Techniques in Spatial Multiomics: Fundamental Principles and Applications to Dermatology. J Invest Dermatol. 2024 Nov 05. Jia BB, Sun BK, Lee EY, Ren B. PMID: 39503694.
      View in: PubMed   Mentions:    Fields:    
    4. Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues. Nat Biotechnol. 2024 Oct 18. Chang L, Xie Y, Taylor B, Wang Z, Sun J, Armand EJ, Mishra S, Xu J, Tastemel M, Lie A, Gibbs ZA, Indralingam HS, Tan TM, Bejar R, Chen CC, Furnari FB, Hu M, Ren B. PMID: 39424717.
      View in: PubMed   Mentions: 1     Fields:    
    5. Epigenetic and 3D genome reprogramming during the aging of human hippocampus. bioRxiv. 2024 Oct 17. Zemke NR, Lee S, Mamde S, Yang B, Berchtold N, Maximiliano Garduño B, Indralingam HS, Bartosik WM, Lau PK, Dong K, Yang A, Tani Y, Chen C, Zeng Q, Ajith V, Tong L, Seng C, Li D, Wang T, Xu X, Ren B. PMID: 39463924; PMCID: PMC11507755.
      View in: PubMed   Mentions:
    6. Built to be imperfect. Nat Cell Biol. 2024 Aug; 26(8):1229-1230. Xu J, Ren B. PMID: 38969761.
      View in: PubMed   Mentions:    Fields:    
    7. RUNX1 C-terminal mutations impair blood cell differentiation by perturbing specific enhancer-promoter networks. Blood Adv. 2024 05 28; 8(10):2410-2423. Jayne ND, Liang Z, Lim DH, Chen PB, Diaz C, Arimoto KI, Xia L, Liu M, Ren B, Fu XD, Zhang DE. PMID: 38513139; PMCID: PMC11112616.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells. bioRxiv. 2024 Apr 22. Chang L, Xie Y, Taylor B, Wang Z, Sun J, Tan TR, Bejar R, Chen CC, Furnari FB, Hu M, Ren B. PMID: 38712075; PMCID: PMC11071305.
      View in: PubMed   Mentions:
    9. H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation. Mol Cell. 2024 May 02; 84(9):1742-1752.e5. Kubo N, Chen PB, Hu R, Ye Z, Sasaki H, Ren B. PMID: 38513661; PMCID: PMC11069443.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Spatially organized cellular communities form the developing human heart. Nature. 2024 Mar; 627(8005):854-864. Farah EN, Hu RK, Kern C, Zhang Q, Lu TY, Ma Q, Tran S, Zhang B, Carlin D, Monell A, Blair AP, Wang Z, Eschbach J, Li B, Destici E, Ren B, Evans SM, Chen S, Zhu Q, Chi NC. PMID: 38480880; PMCID: PMC10972757.
      View in: PubMed   Mentions: 14     Fields:    
    11. Role of H3K4 monomethylation in gene regulation. Curr Opin Genet Dev. 2024 02; 84:102153. Wang Z, Ren B. PMID: 38278054; PMCID: PMC11065453.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. A fast, scalable and versatile tool for analysis of single-cell omics data. Nat Methods. 2024 Feb; 21(2):217-227. Zhang K, Zemke NR, Armand EJ, Ren B. PMID: 38191932; PMCID: PMC10864184.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    13. Author Correction: Conserved and divergent gene regulatory programs of the mammalian neocortex. Nature. 2024 Jan; 625(7996):E26. Zemke NR, Armand EJ, Wang W, Lee S, Zhou J, Li YE, Liu H, Tian W, Nery JR, Castanon RG, Bartlett A, Osteen JK, Li D, Zhuo X, Xu V, Chang L, Dong K, Indralingam HS, Rink JA, Xie Y, Miller M, Krienen FM, Zhang Q, Taskin N, Ting J, Feng G, McCarroll SA, Callaway EM, Wang T, Lein ES, Behrens MM, Ecker JR, Ren B. PMID: 38200319; PMCID: PMC10808050.
      View in: PubMed   Mentions: 1     Fields:    
    14. Single-cell analysis of chromatin accessibility in the adult mouse brain. Nature. 2023 Dec; 624(7991):378-389. Zu S, Li YE, Wang K, Armand EJ, Mamde S, Amaral ML, Wang Y, Chu A, Xie Y, Miller M, Xu J, Wang Z, Zhang K, Jia B, Hou X, Lin L, Yang Q, Lee S, Li B, Kuan S, Liu H, Zhou J, Pinto-Duarte A, Lucero J, Osteen J, Nunn M, Smith KA, Tasic B, Yao Z, Zeng H, Wang Z, Shang J, Behrens MM, Ecker JR, Wang A, Preissl S, Ren B. PMID: 38092917; PMCID: PMC10719105.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    15. Conserved and divergent gene regulatory programs of the mammalian neocortex. Nature. 2023 Dec; 624(7991):390-402. Zemke NR, Armand EJ, Wang W, Lee S, Zhou J, Li YE, Liu H, Tian W, Nery JR, Castanon RG, Bartlett A, Osteen JK, Li D, Zhuo X, Xu V, Chang L, Dong K, Indralingam HS, Rink JA, Xie Y, Miller M, Krienen FM, Zhang Q, Taskin N, Ting J, Feng G, McCarroll SA, Callaway EM, Wang T, Lein ES, Behrens MM, Ecker JR, Ren B. PMID: 38092918; PMCID: PMC10719095.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    16. AP-1 signaling modulates cardiac fibroblast stress responses. J Cell Sci. 2023 12 01; 136(23). Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ. PMID: 37994565; PMCID: PMC10753496.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells. Nat Commun. 2023 10 16; 14(1):6519. Calandrelli R, Wen X, Charles Richard JL, Luo Z, Nguyen TC, Chen CJ, Qi Z, Xue S, Chen W, Yan Z, Wu W, Zaleta-Rivera K, Hu R, Yu M, Wang Y, Li W, Ma J, Ren B, Zhong S. PMID: 37845234; PMCID: PMC10579264.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. A comparative atlas of single-cell chromatin accessibility in the human brain. Science. 2023 10 13; 382(6667):eadf7044. Li YE, Preissl S, Miller M, Johnson ND, Wang Z, Jiao H, Zhu C, Wang Z, Xie Y, Poirion O, Kern C, Pinto-Duarte A, Tian W, Siletti K, Emerson N, Osteen J, Lucero J, Lin L, Yang Q, Zhu Q, Zemke N, Espinoza S, Yanny AM, Nyhus J, Dee N, Casper T, Shapovalova N, Hirschstein D, Hodge RD, Linnarsson S, Bakken T, Levi B, Keene CD, Shang J, Lein E, Wang A, Behrens MM, Ecker JR, Ren B. PMID: 37824643; PMCID: PMC10852054.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    19. [Effect of preimplantation genetic testing for aneuploidies on pregnancy outcome in patients with unexplained recurrent spontaneous abortion]. Zhonghua Yi Xue Za Zhi. 2023 Aug 15; 103(30):2335-2341. Liu MM, Xu SL, Zhang HB, Zhang JW, Ren BN, Zhang WJ, Liu ZZ, Hu JJ, Guan YC. PMID: 37574832.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Droplet-based single-cell joint profiling of histone modifications and transcriptomes. Nat Struct Mol Biol. 2023 10; 30(10):1428-1433. Xie Y, Zhu C, Wang Z, Tastemel M, Chang L, Li YE, Ren B. PMID: 37563440; PMCID: PMC10584685.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. [The effects of high risk of ovarian hyperstimulation syndrome and duration of embryo cryopreservation on perinatal outcomes of single live births in the first frozen embryo transfer cycle after whole embryo cryopreservation]. Zhonghua Yi Xue Za Zhi. 2023 Jul 11; 103(26):1993-1999. Ran SY, Zu RW, Wu H, Zheng W, Yang C, Yang SH, Ren BN, Zhang W, Kuang YH, Li MN, Cao MY, Wu J, Guan YC. PMID: 37438081.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Author Correction: A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH. Nat Biotechnol. 2023 Jul; 41(7):1027. Jia BB, Jussila A, Kern C, Zhu Q, Ren B. PMID: 36646934; PMCID: PMC10344773.
      View in: PubMed   Mentions:    Fields:    
    23. Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes. Cell Genom. 2023 Jul 12; 3(7):100342. Xie F, Armand EJ, Yao Z, Liu H, Bartlett A, Behrens MM, Li YE, Lucero JD, Luo C, Nery JR, Pinto-Duarte A, Poirion OB, Preissl S, Rivkin AC, Tasic B, Zeng H, Ren B, Ecker JR, Mukamel EA. PMID: 37492103; PMCID: PMC10363915.
      View in: PubMed   Mentions: 3     Fields:    
    24. Interpreting non-coding disease-associated human variants using single-cell epigenomics. Nat Rev Genet. 2023 08; 24(8):516-534. Gaulton KJ, Preissl S, Ren B. PMID: 37161089; PMCID: PMC10629587.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    25. Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proc Natl Acad Sci U S A. 2023 05 16; 120(20):e2210991120. Raviram R, Raman A, Preissl S, Ning J, Wu S, Koga T, Zhang K, Brennan CW, Zhu C, Luebeck J, Van Deynze K, Han JY, Hou X, Ye Z, Mischel AK, Li YE, Fang R, Baback T, Mugford J, Han CZ, Glass CK, Barr CL, Mischel PS, Bafna V, Escoubet L, Ren B, Chen CC. PMID: 37155843; PMCID: PMC10194019.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH. Nat Biotechnol. 2023 Jul; 41(7):1004-1017. Jia BB, Jussila A, Kern C, Zhu Q, Ren B. PMID: 36593410; PMCID: PMC10344783.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    27. Author Correction: Human-gained heart enhancers are associated with species-specific cardiac attributes. Nat Cardiovasc Res. 2022 Dec; 1(12):1231. Destici E, Zhu F, Tran S, Preissl S, Farah EN, Zhang Y, Hou X, Poirion OB, Lee AY, Grinstein JD, Bloomekatz J, Kim HS, Hu R, Evans SM, Ren B, Benner C, Chi NC. PMID: 39196171.
      View in: PubMed   Mentions:
    28. Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines. Cell Genom. 2022 Dec 14; 2(12):100214. Benaglio P, Zhu H, Okino ML, Yan J, Elgamal R, Nariai N, Beebe E, Korgaonkar K, Qiu Y, Donovan MKR, Chiou J, Wang G, Newsome J, Kaur J, Miller M, Preissl S, Corban S, Aylward A, Taipale J, Ren B, Frazer KA, Sander M, Gaulton KJ. PMID: 36778047; PMCID: PMC9903835.
      View in: PubMed   Mentions: 8     Fields:    
    29. Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation. Cell Rep. 2022 11 08; 41(6):111630. Chen PB, Fiaux PC, Zhang K, Li B, Kubo N, Jiang S, Hu R, Rooholfada E, Wu S, Wang M, Wang W, McVicker G, Mischel PS, Ren B. PMID: 36351387; PMCID: PMC9687083.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    30. Human-gained heart enhancers are associated with species-specific cardiac attributes. Nat Cardiovasc Res. 2022 Sep; 1(9):830-843. Destici E, Zhu F, Tran S, Preissl S, Farah EN, Zhang Y, Hou X, Poirion OB, Lee AY, Grinstein JD, Bloomekatz J, Kim HS, Hu R, Evans SM, Ren B, Benner C, Chi NC. PMID: 36817700; PMCID: PMC9937543.
      View in: PubMed   Mentions: 3  
    31. Characterizing cis-regulatory elements using single-cell epigenomics. Nat Rev Genet. 2023 01; 24(1):21-43. Preissl S, Gaulton KJ, Ren B. PMID: 35840754; PMCID: PMC9771884.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    32. The Hippo pathway mediates Semaphorin signaling. Sci Adv. 2022 May 27; 8(21):eabl9806. Meng Z, Li FL, Fang C, Yeoman B, Qiu Y, Wang Y, Cai X, Lin KC, Yang D, Luo M, Fu V, Ma X, Diao Y, Giancotti FG, Ren B, Engler AJ, Guan KL. PMID: 35613278; PMCID: PMC9132450.
      View in: PubMed   Mentions: 7     Fields:    
    33. Improved epicardial cardiac fibroblast generation from iPSCs. J Mol Cell Cardiol. 2022 03; 164:58-68. Whitehead AJ, Hocker JD, Ren B, Engler AJ. PMID: 34826415; PMCID: PMC9048147.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    34. Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors. Nat Commun. 2021 11 17; 12(1):6636. Geusz RJ, Wang A, Lam DK, Vinckier NK, Alysandratos KD, Roberts DA, Wang J, Kefalopoulou S, Ramirez A, Qiu Y, Chiou J, Gaulton KJ, Ren B, Kotton DN, Sander M. PMID: 34789735; PMCID: PMC8599738.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    35. A single-cell atlas of chromatin accessibility in the human genome. Cell. 2021 11 24; 184(24):5985-6001.e19. Zhang K, Hocker JD, Miller M, Hou X, Chiou J, Poirion OB, Qiu Y, Li YE, Gaulton KJ, Wang A, Preissl S, Ren B. PMID: 34774128; PMCID: PMC8664161.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansCells
    36. Cardiac cell type-specific gene regulatory programs and disease risk association. Sci Adv. 2021 05; 7(20). Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang TM, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B, Chi NC, Preissl S. PMID: 33990324; PMCID: PMC8121433.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    37. Publisher Correction: Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021 Mar; 591(7850):E19. Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. PMID: 33649505.
      View in: PubMed   Mentions: 4     Fields:    
    38. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. Elife. 2021 02 05; 10. Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDS, Gaulton KJ, Sander M. PMID: 33544077; PMCID: PMC7864636.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    39. KDM1A maintains genome-wide homeostasis of transcriptional enhancers. Genome Res. 2021 Feb; 31(2):186-197. Agarwal S, Bonefas KM, Garay PM, Brookes E, Murata-Nakamura Y, Porter RS, Macfarlan TS, Ren B, Iwase S. PMID: 33414108; PMCID: PMC7849409.
      View in: PubMed   Mentions: 13     Fields:    
    40. Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation. Nat Struct Mol Biol. 2021 02; 28(2):152-161. Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B. PMID: 33398174; PMCID: PMC7913465.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    41. Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021 03; 591(7848):137-141. Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. PMID: 33361815; PMCID: PMC7933129.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansCells
    42. Circular ecDNA promotes accessible chromatin and high oncogene expression. Nature. 2019 11; 575(7784):699-703. Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, Coruh C, Abnousi A, Houston J, Ye Z, Hu R, Yu M, Kim H, Law JA, Verhaak RGW, Hu M, Furnari FB, Chang HY, Ren B, Bafna V, Mischel PS. PMID: 31748743; PMCID: PMC7094777.
      View in: PubMed   Mentions: 225     Fields:    Translation:HumansCells
    43. Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139. Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856; PMCID: PMC7028213.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansCells
    44. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nat Cell Biol. 2019 06; 21(6):743-754. Nechemia-Arbely Y, Miga KH, Shoshani O, Aslanian A, McMahon MA, Lee AY, Fachinetti D, Yates JR, Ren B, Cleveland DW. PMID: 31160708; PMCID: PMC7015266.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    45. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling. Nature. 2019 05; 569(7757):570-575. Chowdhry S, Zanca C, Rajkumar U, Koga T, Diao Y, Raviram R, Liu F, Turner K, Yang H, Brunk E, Bi J, Furnari F, Bafna V, Ren B, Mischel PS. PMID: 31019297; PMCID: PMC7138021.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    46. Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase. Nat Struct Mol Biol. 2019 03; 26(3):164-174. Patel L, Kang R, Rosenberg SC, Qiu Y, Raviram R, Chee S, Hu R, Ren B, Cole F, Corbett KD. PMID: 30778236; PMCID: PMC6403010.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    47. Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation. Cancer Cell. 2019 01 14; 35(1):81-94.e7. Jiang Q, Isquith J, Zipeto MA, Diep RH, Pham J, Delos Santos N, Reynoso E, Chau J, Leu H, Lazzari E, Melese E, Ma W, Fang R, Minden M, Morris S, Ren B, Pineda G, Holm F, Jamieson C. PMID: 30612940; PMCID: PMC6333511.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    48. Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development. Neuro Oncol. 2018 09 03; 20(10):1310-1320. Koga T, Li B, Figueroa JM, Ren B, Chen CC, Carter BS, Furnari FB. PMID: 29660021; PMCID: PMC6120357.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    49. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. 2018 08; 560(7720):655-660. Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. PMID: 30135582; PMCID: PMC6128698.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    50. Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function. Cell. 2018 06 14; 173(7):1796-1809.e17. Link VM, Duttke SH, Chun HB, Holtman IR, Westin E, Hoeksema MA, Abe Y, Skola D, Romanoski CE, Tao J, Fonseca GJ, Troutman TD, Spann NJ, Strid T, Sakai M, Yu M, Hu R, Fang R, Metzler D, Ren B, Glass CK. PMID: 29779944; PMCID: PMC6003872.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    51. NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes. Genes Dev. 2018 05 01; 32(9-10):682-694. Fei J, Ishii H, Hoeksema MA, Meitinger F, Kassavetis GA, Glass CK, Ren B, Kadonaga JT. PMID: 29759984; PMCID: PMC6004073.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    52. Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions. Cell Rep. 2017 Nov 14; 21(7):1870-1882. Lee J, Liao R, Wang G, Yang BH, Luo X, Varki NM, Qiu SJ, Ren B, Fu W, Feng GS. PMID: 29141219; PMCID: PMC5737819.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    53. High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure. Circulation. 2017 Oct 24; 136(17):1613-1625. Rosa-Garrido M, Chapski DJ, Schmitt AD, Kimball TH, Karbassi E, Monte E, Balderas E, Pellegrini M, Shih TT, Soehalim E, Liem D, Ping P, Galjart NJ, Ren S, Wang Y, Ren B, Vondriska TM. PMID: 28802249; PMCID: PMC5648689.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    54. The Three-Dimensional Organization of Mammalian Genomes. Annu Rev Cell Dev Biol. 2017 10 06; 33:265-289. Yu M, Ren B. PMID: 28783961; PMCID: PMC5837811.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimals
    55. Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells. Cell Stem Cell. 2017 04 06; 20(4):533-546.e7. DeBoever C, Li H, Jakubosky D, Benaglio P, Reyna J, Olson KM, Huang H, Biggs W, Sandoval E, D'Antonio M, Jepsen K, Matsui H, Arias A, Ren B, Nariai N, Smith EN, D'Antonio-Chronowska A, Farley EK, Frazer KA. PMID: 28388430; PMCID: PMC5444918.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    56. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. J Cell Biol. 2017 03 06; 216(3):607-621. Nechemia-Arbely Y, Fachinetti D, Miga KH, Sekulic N, Soni GV, Kim DH, Wong AK, Lee AY, Nguyen K, Dekker C, Ren B, Black BE, Cleveland DW. PMID: 28235947; PMCID: PMC5350519.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    57. Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. Nature. 2017 03 02; 543(7643):122-125. Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. PMID: 28178237; PMCID: PMC5334176.
      View in: PubMed   Mentions: 343     Fields:    Translation:HumansCells
    58. A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome. Cell Rep. 2016 11 15; 17(8):2042-2059. Schmitt AD, Hu M, Jung I, Xu Z, Qiu Y, Tan CL, Li Y, Lin S, Lin Y, Barr CL, Ren B. PMID: 27851967; PMCID: PMC5478386.
      View in: PubMed   Mentions: 410     Fields:    Translation:HumansAnimalsCells
    59. Genome-wide mapping and analysis of chromosome architecture. Nat Rev Mol Cell Biol. 2016 12; 17(12):743-755. Schmitt AD, Hu M, Ren B. PMID: 27580841; PMCID: PMC5763923.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCells
    60. A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. Genome Res. 2016 Mar; 26(3):397-405. Diao Y, Li B, Meng Z, Jung I, Lee AY, Dixon J, Maliskova L, Guan KL, Shen Y, Ren B. PMID: 26813977; PMCID: PMC4772021.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    61. Transcriptional Enhancers: Bridging the Genome and Phenome. Cold Spring Harb Symp Quant Biol. 2015; 80:17-26. Ren B, Yue F. PMID: 26582789.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    62. Human body epigenome maps reveal noncanonical DNA methylation variation. Nature. 2015 Jul 09; 523(7559):212-6. Schultz MD, He Y, Whitaker JW, Hariharan M, Mukamel EA, Leung D, Rajagopal N, Nery JR, Urich MA, Chen H, Lin S, Lin Y, Jung I, Schmitt AD, Selvaraj S, Ren B, Sejnowski TJ, Wang W, Ecker JR. PMID: 26030523; PMCID: PMC4499021.
      View in: PubMed   Mentions: 359     Fields:    Translation:HumansCells
    63. A CRISPR Connection between Chromatin Topology and Genetic Disorders. Cell. 2015 May 21; 161(5):955-957. Ren B, Dixon JR. PMID: 26000472; PMCID: PMC4478077.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    64. Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell. 2015 Apr 02; 16(4):386-99. Wang A, Yue F, Li Y, Xie R, Harper T, Patel NA, Muth K, Palmer J, Qiu Y, Wang J, Lam DK, Raum JC, Stoffers DA, Ren B, Sander M. PMID: 25842977; PMCID: PMC4478079.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    65. Chromatin architecture reorganization during stem cell differentiation. Nature. 2015 Feb 19; 518(7539):331-6. Dixon JR, Jung I, Selvaraj S, Shen Y, Antosiewicz-Bourget JE, Lee AY, Ye Z, Kim A, Rajagopal N, Xie W, Diao Y, Liang J, Zhao H, Lobanenkov VV, Ecker JR, Thomson JA, Ren B. PMID: 25693564; PMCID: PMC4515363.
      View in: PubMed   Mentions: 802     Fields:    Translation:HumansCells
    66. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 2014 Nov 20; 515(7527):355-64. Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B, Mouse ENCODE Consortium. PMID: 25409824; PMCID: PMC4266106.
      View in: PubMed   Mentions: 895     Fields:    Translation:HumansAnimalsCells
    67. Distinct and predictive histone lysine acetylation patterns at promoters, enhancers, and gene bodies. G3 (Bethesda). 2014 Aug 12; 4(11):2051-63. Rajagopal N, Ernst J, Ray P, Wu J, Zhang M, Kellis M, Ren B. PMID: 25122670; PMCID: PMC4232531.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    68. The 3D genome in transcriptional regulation and pluripotency. Cell Stem Cell. 2014 Jun 05; 14(6):762-75. Gorkin DU, Leung D, Ren B. PMID: 24905166; PMCID: PMC4107214.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    69. Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1. Proc Natl Acad Sci U S A. 2014 May 06; 111(18):6690-5. Leung D, Du T, Wagner U, Xie W, Lee AY, Goyal P, Li Y, Szulwach KE, Jin P, Lorincz MC, Ren B. PMID: 24757056; PMCID: PMC4020067.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    70. Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing. Nat Biotechnol. 2013 Dec; 31(12):1111-8. Selvaraj S, R Dixon J, Bansal V, Ren B. PMID: 24185094; PMCID: PMC4180835.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansCells
    71. STAR: an integrated solution to management and visualization of sequencing data. Bioinformatics. 2013 Dec 15; 29(24):3204-10. Wang T, Liu J, Shen L, Tonti-Filippini J, Zhu Y, Jia H, Lister R, Whitaker JW, Ecker JR, Millar AH, Ren B, Wang W. PMID: 24078702; PMCID: PMC3842760.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    72. Mapping human epigenomes. Cell. 2013 Sep 26; 155(1):39-55. Rivera CM, Ren B. PMID: 24074860; PMCID: PMC3838898.
      View in: PubMed   Mentions: 261     Fields:    Translation:HumansAnimalsCells
    73. Developmental biology. Enhancing pluripotency and lineage specification. Science. 2013 Jul 19; 341(6143):245-7. Xie W, Ren B. PMID: 23869010.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    74. RFECS: a random-forest based algorithm for enhancer identification from chromatin state. PLoS Comput Biol. 2013; 9(3):e1002968. Rajagopal N, Xie W, Li Y, Wagner U, Wang W, Stamatoyannopoulos J, Ernst J, Kellis M, Ren B. PMID: 23526891; PMCID: PMC3597546.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansCells
    75. Comparative annotation of functional regions in the human genome using epigenomic data. Nucleic Acids Res. 2013 Apr; 41(8):4423-32. Won KJ, Zhang X, Wang T, Ding B, Raha D, Snyder M, Ren B, Wang W. PMID: 23482391; PMCID: PMC3632130.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    76. Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML. Blood. 2012 Aug 16; 120(7):1473-84. Lo MC, Peterson LF, Yan M, Cong X, Jin F, Shia WJ, Matsuura S, Ahn EY, Komeno Y, Ly M, Ommen HB, Chen IM, Hokland P, Willman CL, Ren B, Zhang DE. PMID: 22740448; PMCID: PMC3423785.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    77. Enhancers: multi-dimensional signal integrators. Transcription. 2011 Sep-Oct; 2(5):226-30. Jin F, Li Y, Ren B, Natarajan R. PMID: 22231119; PMCID: PMC3265780.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    78. Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency. Cell Res. 2011 Oct; 21(10):1393-409. Hawkins RD, Hon GC, Yang C, Antosiewicz-Bourget JE, Lee LK, Ngo QM, Klugman S, Ching KA, Edsall LE, Ye Z, Kuan S, Yu P, Liu H, Zhang X, Green RD, Lobanenkov VV, Stewart R, Thomson JA, Ren B. PMID: 21876557; PMCID: PMC3193447.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    79. PU.1 and C/EBP(alpha) synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5290-5. Jin F, Li Y, Ren B, Natarajan R. PMID: 21402921; PMCID: PMC3069155.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    80. 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature. 2011 Feb 10; 470(7333):264-8. Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. PMID: 21307941; PMCID: PMC3079517.
      View in: PubMed   Mentions: 318     Fields:    Translation:HumansCells
    81. Next-generation genomics: an integrative approach. Nat Rev Genet. 2010 Jul; 11(7):476-86. Hawkins RD, Hon GC, Ren B. PMID: 20531367; PMCID: PMC3321268.
      View in: PubMed   Mentions: 275     Fields:    
    82. Genome-wide prediction of transcription factor binding sites using an integrated model. Genome Biol. 2010 Jan 22; 11(1):R7. Won KJ, Ren B, Wang W. PMID: 20096096; PMCID: PMC2847719.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    83. Discovery and annotation of functional chromatin signatures in the human genome. PLoS Comput Biol. 2009 Nov; 5(11):e1000566. Hon G, Wang W, Ren B. PMID: 19918365; PMCID: PMC2775352.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    84. Finding distal regulatory elements in the human genome. Curr Opin Genet Dev. 2009 Dec; 19(6):541-9. Heintzman ND, Ren B. PMID: 19854636; PMCID: PMC3321269.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansCells
    85. Predictive chromatin signatures in the mammalian genome. Hum Mol Genet. 2009 Oct 15; 18(R2):R195-201. Hon GC, Hawkins RD, Ren B. PMID: 19808796; PMCID: PMC2912651.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    86. An integrated approach to identifying cis-regulatory modules in the human genome. PLoS One. 2009; 4(5):e5501. Won KJ, Agarwal S, Shen L, Shoemaker R, Ren B, Wang W. PMID: 19434238; PMCID: PMC2677454.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    87. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature. 2009 May 07; 459(7243):108-12. Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF, Ye Z, Lee LK, Stuart RK, Ching CW, Ching KA, Antosiewicz-Bourget JE, Liu H, Zhang X, Green RD, Lobanenkov VV, Stewart R, Thomson JA, Crawford GE, Kellis M, Ren B. PMID: 19295514; PMCID: PMC2910248.
      View in: PubMed   Mentions: 1471     Fields:    Translation:HumansCells
    88. Prediction of regulatory elements in mammalian genomes using chromatin signatures. BMC Bioinformatics. 2008 Dec 18; 9:547. Won KJ, Chepelev I, Ren B, Wang W. PMID: 19094206; PMCID: PMC2657164.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    89. ChromaSig: a probabilistic approach to finding common chromatin signatures in the human genome. PLoS Comput Biol. 2008 Oct; 4(10):e1000201. Hon G, Ren B, Wang W. PMID: 18927605; PMCID: PMC2556089.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    90. Genome-wide mapping of allele-specific protein-DNA interactions in human cells. Nat Methods. 2008 Apr; 5(4):307-9. Maynard ND, Chen J, Stuart RK, Fan JB, Ren B. PMID: 18345007.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    91. Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res. 2008 Jan; 18(1):46-59. Barrera LO, Li Z, Smith AD, Arden KC, Cavenee WK, Zhang MQ, Green RD, Ren B. PMID: 18042645; PMCID: PMC2134779.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    92. Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. Cell. 2007 Mar 23; 128(6):1231-45. Kim TH, Abdullaev ZK, Smith AD, Ching KA, Loukinov DI, Green RD, Zhang MQ, Lobanenkov VV, Ren B. PMID: 17382889; PMCID: PMC2572726.
      View in: PubMed   Mentions: 617     Fields:    Translation:HumansAnimalsCells
    93. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet. 2007 Mar; 39(3):311-8. Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, Hawkins RD, Barrera LO, Van Calcar S, Qu C, Ching KA, Wang W, Weng Z, Green RD, Crawford GE, Ren B. PMID: 17277777.
      View in: PubMed   Mentions: 1893     Fields:    Translation:HumansCells
    94. Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res. 2006 Jun 01; 66(11):5565-73. Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A. PMID: 16740691.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    95. The transcriptional regulatory code of eukaryotic cells--insights from genome-wide analysis of chromatin organization and transcription factor binding. Curr Opin Cell Biol. 2006 Jun; 18(3):291-8. Barrera LO, Ren B. PMID: 16647254.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    96. Genome-wide location analysis: insights on transcriptional regulation. Hum Mol Genet. 2006 Apr 15; 15 Spec No 1:R1-7. Hawkins RD, Ren B. PMID: 16651365.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    97. Genome-wide analysis of protein-DNA interactions. Annu Rev Genomics Hum Genet. 2006; 7:81-102. Kim TH, Ren B. PMID: 16722805.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    98. An all-round view of eukaryotic transcription. Genome Biol. 2006; 7(7):323. Kim TH, Ren B. PMID: 16879733; PMCID: PMC1779551.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    99. A high-resolution map of active promoters in the human genome. Nature. 2005 Aug 11; 436(7052):876-80. Kim TH, Barrera LO, Zheng M, Qu C, Singer MA, Richmond TA, Wu Y, Green RD, Ren B. PMID: 15988478; PMCID: PMC1895599.
      View in: PubMed   Mentions: 512     Fields:    Translation:HumansCells
    100. Direct isolation and identification of promoters in the human genome. Genome Res. 2005 Jun; 15(6):830-9. Kim TH, Barrera LO, Qu C, Van Calcar S, Trinklein ND, Cooper SJ, Luna RM, Glass CK, Rosenfeld MG, Myers RM, Ren B. PMID: 15899964; PMCID: PMC1142473.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    101. beta-Catenin activates the growth factor endothelin-1 in colon cancer cells. Oncogene. 2005 Jan 20; 24(4):597-604. Kim TH, Xiong H, Zhang Z, Ren B. PMID: 15558022.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    102. Use of chromatin immunoprecipitation assays in genome-wide location analysis of mammalian transcription factors. Methods Enzymol. 2004; 376:304-15. Ren B, Dynlacht BD. PMID: 14975314.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    103. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8164-9. Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. PMID: 12808131; PMCID: PMC166200.
      View in: PubMed   Mentions: 255     Fields:    Translation:HumansCells
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