Tony Yaksh

Title(s)Recall Faculty, Anesthesiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    B.S.Georgia Institute of Technology
    M.S.University of Georgia
    Ph.D.Purdue University
    Collapse Awards and Honors
    1995American Society of Anesthesiology (ASA) Award for Excellence in Research;
    1996Emmanuel Papper Lecturer, Columbia Presbyterian Hospital
    1998Joris De Castro Memorial Lecture - Belgian Society of Anaesthesia and Reanimation
    1998American Academy of Pain Medicine, Award for Outstanding Contributions to Pain Medicine
    1999UCSD Chancellor’s Associates Faculty Excellence Award in Research
    1999American Academy of Pain Management, The John Liebeskind Award for Pain Research
    2000Swedish Society of Medicine, Torsten Gordh lecturer
    2001New York Society of Anesthesiologists Rovenstine Lecturer
    2007Javitz Award in Neuroscience; National Institute of Neurological, Communicative Diseases and Stroke
    2007Schueler Distinguished Lecturer award, Tulane University
    2007Seldon Memorial Lecturer award, International Anesthesia Research Society
    2007German Promotion Award for Pain Research and Therapy, German Pain Association
    2008ohn J. Bonica Distinguished Lecturer, International Association for the Study of Pain
    2012Presidential Commendation, World Institute of Pain
    2015Lifetime achievement award (North American Neuromodulation Society - NANS)
    2017Spain Distinguished Service Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Pre-clinical evaluation of DT-001, a small molecule antagonist of MD2-TLR4 for utility in the treatment of pain.
    NIH R41NS113717Sep 30, 2019 - Aug 31, 2021
    Role: Principal Investigator
    New Approach to Atopic Dermatitis
    NIH R43AR072546Sep 1, 2018 - Aug 31, 2021
    Role: Co-Principal Investigator
    Reversal of preexisting neuropathic pain by spinal delivery of AIBP
    NIH R33NS104769Aug 1, 2018 - Jul 31, 2021
    Role: Co-Principal Investigator
    Reversal of preexisting neuropathic pain by spinal delivery of AIBP
    NIH R21NS104769Aug 1, 2018 - Jul 31, 2020
    Role: Co-Principal Investigator
    AIBP and regulation of neuropathic pain
    NIH R01NS102432Aug 15, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Sex, Stress and Immunity in the Acute to Chronic Pain Transition
    NIH R01NS099338Dec 15, 2016 - Nov 30, 2021
    Role: Principal Investigator
    Construction and Analysis of BoNT derivatives as Pain Specific Inhibitors
    NIH R21AI113580Aug 7, 2014 - Jul 31, 2016
    Role: Principal Investigator
    Discovery of novel small molecule analgesics
    NIH R41NS086244May 15, 2014 - Dec 31, 2015
    Role: Principal Investigator
    Myelin Autoantigens in Neuropathic Pain
    NIH R01DE022757Jul 30, 2012 - Aug 31, 2023
    Role: Principal Investigator
    The role of selective brain penetrating GRPR antagonists in pruritis.
    NIH R21NS077348Sep 30, 2011 - Dec 30, 2013
    Role: Principal Investigator
    Pain Mechanisms and the Development of Analgesics
    NIH R13DA021484Mar 1, 2006 - Feb 28, 2007
    Role: Principal Investigator
    Characterization of Toxicity with Spinal Opiates
    NIH R01DA015353Jul 1, 2002 - Jun 30, 2020
    Role: Principal Investigator
    Spinal Galanin and its Receptors in Pain Processing
    NIH R01NS041954Jun 1, 2002 - May 31, 2006
    Role: Principal Investigator
    Neurobiology of Pain
    NIH T32NS007407Jul 1, 1997 - Jun 30, 2007
    Role: Principal Investigator
    PRECLINICAL TOXICOLOGY STUDIES OF NMDA ANTAGONISTS
    NIH R01NS033846Aug 1, 1994 - Jul 31, 1998
    Role: Principal Investigator
    NEW MODALITIES FOR TREATMENT OF PAIN AND DRUG ABUSE
    NIH P01DA006284Sep 30, 1989 - Mar 31, 2016
    Role: Co-Investigator
    Pain Evoked Release of Amino Acids and Prostanoids
    NIH R37NS016541Sep 1, 1988 - Feb 28, 2013
    Role: Principal Investigator
    PEPTIDE RELEASE FROM PERIPHERAL TERMINALS OF AFFERENTS
    NIH R01AI026249Apr 1, 1988 - Mar 31, 1992
    Role: Principal Investigator
    The Pharmacology of Spinal Analgesics
    NIH R01DA002110Jul 1, 1983 - Jan 31, 2016
    Role: Principal Investigator
    SPINAL PHARMACOLOGY OF BLADDER FUNCTION
    NIH R01NS019650Jul 1, 1983 - Jun 30, 1986
    Role: Principal Investigator
    PAIN EVOKED RELEASE OF AMINO ACIDS AND PROSTANOIDS
    NIH R01NS016541Jul 1, 1980 - Dec 31, 2005
    Role: Principal Investigator
    Specialized Cancer Center Support Grant
    NIH P30CA023100Apr 1, 1978 - Apr 30, 2024
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Virally-initiated pain states: phenotypes, mechanisms, and future directions. Front Pain Res (Lausanne). 2025; 6:1527106. Dochnal SA, Cohen SP, Hutchinson MR, Miller YI, Yaksh TL. PMID: 39958365; PMCID: PMC11822861.
      View in: PubMed   Mentions:
    2. Role of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis. Arthritis Res Ther. 2024 Dec 18; 26(1):212. Dos Santos GG, Jiménez-Andrade JM, Muñoz-Islas E, Candanedo-Quiroz ME, Cardenas AG, Drummond B, Pham P, Stilson G, Hsu CC, Delay L, Navia-Pelaez JM, Lemes JP, Miller YI, Yaksh TL, Corr M. PMID: 39696684; PMCID: PMC11654167.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. A perspective: neuraxial therapeutics in pain management: now and future. Front Pain Res (Lausanne). 2024; 5:1505019. DeAndres J, Dickenson AH, Hayek S, Linninger A, Yaksh TL. PMID: 39720319; PMCID: PMC11666549.
      View in: PubMed   Mentions:
    4. Non-invasive evaluation of Achilles tendon and its enthesis using ultrashort echo time adiabatic T1ρ (UTE-Adiab-T1ρ) magnetic resonance imaging (MRI) in psoriatic arthritis. Eur J Radiol. 2025 Feb; 183:111841. Moazamian D, Mohammadi HS, Athertya J, Daskareh M, Ma Y, Guma M, Covey DC, Yaksh T, Singh A, Kavanaugh A, Chung CB, Du J, Chang EY, Jerban S. PMID: 39667119.
      View in: PubMed   Mentions:    Fields:    
    5. ApoA-I binding protein (AIBP) regulates transient receptor potential vanilloid 1 (TRPV1) activity in rat dorsal root ganglion neurons by selective disruption of toll-like receptor 4 (TLR4)-lipid rafts. Brain Behav Immun. 2025 Jan; 123:644-655. Li Y, Uhelski ML, North RY, Farson LB, Bankston CB, Roland GH, Fan DH, Sheffield KN, Jia A, Orlando D, Heles M, Yaksh TL, Miller YI, Kosten TA, Dougherty PM. PMID: 39414176.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. The Polyanalgesic Consensus Conference (PACC)®: Updates on Clinical Pharmacology and Comorbidity Management in Intrathecal Drug Delivery for Cancer Pain. Neuromodulation. 2024 Sep 20. Deer TR, Hayek SM, Grider JS, Pope JE, Brogan SE, Gulati A, Hagedorn JM, Strand N, Hah J, Yaksh TL, Staats PS, Perruchoud C, Knezevic NN, Wallace MS, Pilitsis JG, Lamer TJ, Buchser E, Varshney V, Osborn J, Goel V, Simpson BA, Lopez JA, Dupoiron D, Saulino MF, McDowell GC, Piedimonte F, Levy RM. PMID: 39297833.
      View in: PubMed   Mentions:    Fields:    
    7. Acetaminophen effects upon formalin-evoked flinching, postformalin, and postincisional allodynia and conditioned place preference. Pain Rep. 2024 Oct; 9(5):e1168. Yun M, Regen ND, Anchondo Y, Eddinger K, Malkmus S, Roberts SW, Donati E, Leonardi A, Yaksh TL. PMID: 39139364; PMCID: PMC11321755.
      View in: PubMed   Mentions:
    8. The Polyanalgesic Consensus Conference (PACC)®: Intrathecal Drug Delivery Guidance on Safety and Therapy Optimization When Treating Chronic Noncancer Pain. Neuromodulation. 2024 Oct; 27(7):1107-1139. Deer TR, Hayek SM, Grider JS, Hagedorn JM, McDowell GC, Kim P, Dupoiron D, Goel V, Duarte R, Pilitsis JG, Leong MS, De Andrés J, Perruchoud C, Sukumaran H, Abd-Elsayed A, Saulino M, Patin D, Poree LR, Strand N, Gritsenko K, Osborn JA, Dones I, Bux A, Shah JM, Lindsey BL, Shaw E, Yaksh TL, Levy RM. PMID: 38752946.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation. Sci Adv. 2024 Apr 26; 10(17):eadj9581. Lubejko ST, Livrizzi G, Buczynski SA, Patel J, Yung JC, Yaksh TL, Banghart MR. PMID: 38669335; PMCID: PMC11051679.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    10. 12/15-Lipoxygenases mediate neuropathic-like pain hypersensitivity in female mice. bioRxiv. 2024 Apr 08. Brown B, Chen I, Miliano C, Murdaugh LB, Dong Y, Eddinger KA, Yaksh TL, Burton MD, Buczynski MW, Gregus AM. PMID: 38644994; PMCID: PMC11030227.
      View in: PubMed   Mentions:
    11. Cholesterol-dependent LXR transcription factor activity represses pronociceptive effects of estrogen in sensory neurons and pain induced by myelin basic protein fragments. Brain Behav Immun Health. 2024 Jul; 38:100757. Hullugundi SK, Dolkas J, Chernov AV, Yaksh TL, Eddinger KA, Angert M, Catroli GF, Strongin AY, Dougherty PM, Li Y, Quehenberger O, Armando A, Shubayev VI. PMID: 38590761; PMCID: PMC10999831.
      View in: PubMed   Mentions:
    12. Pain mechanisms in the transgender individual: a review. Front Pain Res (Lausanne). 2024; 5:1241015. Anger JT, Case LK, Baranowski AP, Berger A, Craft RM, Damitz LA, Gabriel R, Harrison T, Kaptein K, Lee S, Murphy AZ, Said E, Smith SA, Thomas DA, Valdés Hernández MDC, Trasvina V, Wesselmann U, Yaksh TL. PMID: 38601924; PMCID: PMC11004280.
      View in: PubMed   Mentions:
    13. Catheter Tip-Associated Mass With Continuous Infusion of Sufentanil for Persistent Spinal Pain Syndrome Type 2: A Case Report Including Histopathologic Examination and Review of the Associated Basic and Clinical Research. Neuromodulation. 2024 Oct; 27(7):1140-1148. Pisansky AJB, MacDougall BJ, Ross EL, Chi JH, Neville G, Yaksh TL. PMID: 38441505.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. CD163+ macrophages monitor enhanced permeability at the blood-dorsal root ganglion barrier. J Exp Med. 2024 Feb 05; 221(2). Lund H, Hunt MA, Kurtovic Z, Sandor K, Kägy PB, Fereydouni N, Julien A, Göritz C, Vazquez-Liebanas E, Andaloussi Mäe M, Jurczak A, Han J, Zhu K, Harris RA, Lampa J, Graversen JH, Etzerodt A, Haglund L, Yaksh TL, Svensson CI. PMID: 38117255; PMCID: PMC10733632.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    15. Refinement of intrathecal catheter design to enhance neuraxial distribution. J Neurosci Methods. 2024 02; 402:110006. Hunt MA, Hunt SAC, Edinger K, Steinauer J, Yaksh TL. PMID: 37967672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation. bioRxiv. 2023 Oct 10. Lubejko ST, Livrizzi G, Patel J, Yung JC, Yaksh TL, Banghart MR. PMID: 37873091; PMCID: PMC10592708.
      View in: PubMed   Mentions:
    17. Hydration-induced Void-containing Hydrogels for Encapsulation and Sustained Release of Small Hydrophilic Molecules. Adv Funct Mater. 2023 Aug 22; 33(34). Li Q, Li X, Bury E, Koh A, Lackey K, Wesselmann U, Yaksh T, Zhao C. PMID: 38046826; PMCID: PMC10691822.
      View in: PubMed   Mentions: 3  
    18. Neuraxial drug delivery in pain management: An overview of past, present, and future. Best Pract Res Clin Anaesthesiol. 2023 Jun; 37(2):243-265. Yaksh TL, Santos GGD, Borges Paes Lemes J, Malange K. PMID: 37321769.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Corrigendum: Intrathecal drug delivery: Advances and applications in the management of chronic pain patient. Front Pain Res (Lausanne). 2023; 4:1190014. De Andres J, Hayek S, Perruchoud C, Lawrence MM, Reina MA, De Andres-Serrano C, Rubio-Haro R, Hunt M, Yaksh TL. PMID: 37113213; PMCID: PMC10128988.
      View in: PubMed   Mentions: 1  
    20. AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons. Pain. 2023 06 01; 164(6):e274-e285. Navia-Pelaez JM, Borges Paes Lemes J, Gonzalez L, Delay L, Dos Santos Aggum Capettini L, Lu JW, Gonçalves Dos Santos G, Gregus AM, Dougherty PM, Yaksh TL, Miller YI. PMID: 36719418; PMCID: PMC10182209.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    21. Macrophages and glial cells: Innate immune drivers of inflammatory arthritic pain perception from peripheral joints to the central nervous system. Front Pain Res (Lausanne). 2022; 3:1018800. Malange KF, Navia-Pelaez JM, Dias EV, Lemes JBP, Choi SH, Dos Santos GG, Yaksh TL, Corr M. PMID: 36387416; PMCID: PMC9644179.
      View in: PubMed   Mentions: 3  
    22. Emulsion-induced polymersomes taming tetrodotoxin for prolonged duration local anesthesia. Adv Ther (Weinh). 2023 Jan; 6(1). Li X, Li Q, Song S, Stevens AO, Broemmel Z, He Y, Wesselmann U, Yaksh T, Zhao C. PMID: 36819711; PMCID: PMC9937052.
      View in: PubMed   Mentions: 4  
    23. Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model. Brain. 2022 06 30; 145(6):1962-1977. Avansini SH, Puppo F, Adams JW, Vieira AS, Coan AC, Rogerio F, Torres FR, Araújo PAOR, Martin M, Montenegro MA, Yasuda CL, Tedeschi H, Ghizoni E, França AFEC, Alvim MKM, Athié MC, Rocha CS, Almeida VS, Dias EV, Delay L, Molina E, Yaksh TL, Cendes F, Lopes Cendes I, Muotri AR. PMID: 34957478; PMCID: PMC9336577.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    24. Intrathecal Drug Delivery: Advances and Applications in the Management of Chronic Pain Patient. Front Pain Res (Lausanne). 2022; 3:900566. De Andres J, Hayek S, Perruchoud C, Lawrence MM, Reina MA, De Andres-Serrano C, Rubio-Haro R, Hunt M, Yaksh TL. PMID: 35782225; PMCID: PMC9246706.
      View in: PubMed   Mentions: 15  
    25. Sex-Specific B Cell and Anti-Myelin Autoantibody Response After Peripheral Nerve Injury. Front Cell Neurosci. 2022; 16:835800. Lee HJ, Remacle AG, Hullugundi SK, Dolkas J, Leung JB, Chernov AV, Yaksh TL, Strongin AY, Shubayev VI. PMID: 35496906; PMCID: PMC9050049.
      View in: PubMed   Mentions: 5  
    26. DRGquant: A new modular AI-based pipeline for 3D analysis of the DRG. J Neurosci Methods. 2022 Apr 01; 371:109497. Hunt MA, Lund H, Delay L, Dos Santos GG, Pham A, Kurtovic Z, Telang A, Lee A, Parvathaneni A, Kussick E, Corr M, Yaksh TL. PMID: 35181343; PMCID: PMC10644910.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    27. Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli. Cells. 2021 12 09; 10(12). Lee S, Lee J, Khimji C, Lee J, Malkmus S, Albo M, Yaksh T, Chiang G. PMID: 34943985; PMCID: PMC8700116.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    28. Evaluation of neurotoxicity and long-term function and behavior following intrathecal 1 % 2-chloroprocaine in juvenile rats. Neurotoxicology. 2022 01; 88:155-167. Walker SM, Malkmus S, Eddinger K, Steinauer J, Roberts AJ, Shubayev VI, Grafe MR, Powell SB, Yaksh TL. PMID: 34801587.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    29. Systematic Review of Systemic and Neuraxial Effects of Acetaminophen in Preclinical Models of Nociceptive Processing. J Pain Res. 2021; 14:3521-3552. Hoshijima H, Hunt M, Nagasaka H, Yaksh T. PMID: 34795520; PMCID: PMC8594782.
      View in: PubMed   Mentions: 6  
    30. Severe altered mentation due to cervicothoracic intrathecal pump after correction of cervical stenosis: a case report. Reg Anesth Pain Med. 2021 12; 46(12):1100-1102. Sanghvi C, Su T, Yaksh TL, Copenhaver DJ, Klineberg EO, Jung MJ. PMID: 34489354.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Sex differences in neuroimmune and glial mechanisms of pain. Pain. 2021 08 01; 162(8):2186-2200. Gregus AM, Levine IS, Eddinger KA, Yaksh TL, Buczynski MW. PMID: 34256379; PMCID: PMC8277970.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    32. Treating osteoarthritis pain: mechanisms of action of acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, and nerve growth factor antibodies. Postgrad Med. 2021 Nov; 133(8):879-894. D'Arcy Y, Mantyh P, Yaksh T, Donevan S, Hall J, Sadrarhami M, Viktrup L. PMID: 34252357.
      View in: PubMed   Mentions: 19     Fields:    
    33. Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain. J Exp Med. 2021 07 05; 218(7). Navia-Pelaez JM, Choi SH, Dos Santos Aggum Capettini L, Xia Y, Gonen A, Agatisa-Boyle C, Delay L, Gonçalves Dos Santos G, Catroli GF, Kim J, Lu JW, Saylor B, Winkels H, Durant CP, Ghosheh Y, Beaton G, Ley K, Kufareva I, Corr M, Yaksh TL, Miller YI. PMID: 33970188; PMCID: PMC8111462.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    34. Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice. Sci Transl Med. 2021 03 10; 13(584). Moreno AM, Alemán F, Catroli GF, Hunt M, Hu M, Dailamy A, Pla A, Woller SA, Palmer N, Parekh U, McDonald D, Roberts AJ, Goodwill V, Dryden I, Hevner RF, Delay L, Gonçalves Dos Santos G, Yaksh TL, Mali P. PMID: 33692134; PMCID: PMC8830379.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    35. Sexual Dimorphism in the Expression of Pain Phenotype in Preclinical Models of Rheumatoid Arthritis. Rheum Dis Clin North Am. 2021 05; 47(2):245-264. Delay L, Gonçalves Dos Santos G, Dias EV, Yaksh TL, Corr M. PMID: 33781493; PMCID: PMC8015200.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    36. Frontiers in Pain Research: A Scope of Its Focus and Content. Front Pain Res (Lausanne). 2020; 1:601528. Yaksh TL. PMID: 35295691; PMCID: PMC8915630.
      View in: PubMed   Mentions: 1  
    37. Unintended consequences of COVID-19 safety measures on patients with chronic knee pain forced to defer joint replacement surgery. Pain Rep. 2020 Nov-Dec; 5(6):e855. Cisternas AF, Ramachandran R, Yaksh TL, Nahama A. PMID: 33134751; PMCID: PMC7553566.
      View in: PubMed   Mentions: 27  
    38. The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling. Sci Rep. 2020 09 24; 10(1):15596. Gonçalves Dos Santos G, Jimenéz-Andrade JM, Woller SA, Muñoz-Islas E, Ramírez-Rosas MB, Ohashi N, Ferreira Catroli G, Fujita Y, Yaksh TL, Corr M. PMID: 32973194; PMCID: PMC7515905.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    39. Topical Application of ASN008, a Permanently Charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset, and Long Duration of Action in a Mouse Model of Pruritus. J Pharmacol Exp Ther. 2020 09; 374(3):521-528. Ramachandran R, Thompson SK, Malkmus S, Mieda T, Lin JH, Gupta S, Yaksh TL. PMID: 32616515.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    40. A myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice. J Biol Chem. 2020 07 31; 295(31):10807-10821. Chernov AV, Hullugundi SK, Eddinger KA, Dolkas J, Remacle AG, Angert M, James BP, Yaksh TL, Strongin AY, Shubayev VI. PMID: 32532796; PMCID: PMC7397096.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    41. Pharmacodynamics of intrathecal and epidural fadolmidine, an α2-adrenoceptor agonist, after bolus and infusion in dogs-comparison with clonidine. Naunyn Schmiedebergs Arch Pharmacol. 2020 08; 393(8):1459-1473. Leino T, Yaksh T, Horais K, Haapalinna A. PMID: 32179953.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    42. Neuraxial Cytokines in Pain States. Front Immunol. 2019; 10:3061. Gonçalves Dos Santos G, Delay L, Yaksh TL, Corr M. PMID: 32047493; PMCID: PMC6997465.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    43. Lipid rafts in glial cells: role in neuroinflammation and pain processing. J Lipid Res. 2020 05; 61(5):655-666. Miller YI, Navia-Pelaez JM, Corr M, Yaksh TL. PMID: 31862695; PMCID: PMC7193960.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    44. Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety. Pain. 2019 10; 160(10):2210-2220. Schmelz M, Mantyh P, Malfait AM, Farrar J, Yaksh T, Tive L, Viktrup L. PMID: 31145219; PMCID: PMC6756297.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    45. Mast Cell Degranulation and Fibroblast Activation in the Morphine-induced Spinal Mass: Role of Mas-related G Protein-coupled Receptor Signaling. Anesthesiology. 2019 07; 131(1):132-147. Yaksh TL, Eddinger KA, Kokubu S, Wang Z, DiNardo A, Ramachandran R, Zhu Y, He Y, Weren F, Quang D, Malkmus SA, Lansu K, Kroeze WK, Eliceiri B, Steinauer JJ, Schiller PW, Gmeiner P, Page LM, Hildebrand KR. PMID: 31225809; PMCID: PMC6590697.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    46. Characterization of Effect of Repeated Bolus or Continuous Intrathecal Infusion of Morphine on Spinal Mass Formation in the Dog. Neuromodulation. 2019 Oct; 22(7):790-798. Hildebrand KR, Page LM, Billstrom TM, Steinauer JJ, Eddinger KA, Arjomand S, Yaksh TL. PMID: 31124198; PMCID: PMC6803019.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    47. Unilateral Epidural Targeting of Resiniferatoxin Induces Bilateral Neurolysis of Spinal Nociceptive Afferents. Pain Med. 2019 05 01; 20(5):897-906. Unger MD, Pleticha J, Steinauer J, Kanwar R, Diehn F, LaVallee KT, Banck MS, Jones B, Yaksh TL, Maus TP, Beutler AS. PMID: 30590777.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    48. Characterization of Analgesic Actions of the Chronic Intrathecal Infusion of H-Dmt-D-Arg-Phe-Lys-NH2 in Rat. Neuromodulation. 2019 Oct; 22(7):781-789. Kokubu S, Eddinger KA, Yamaguchi S, Huerta-Esquivel LL, Schiller PW, Yaksh TL. PMID: 30794333; PMCID: PMC6706328.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    49. Letter to Editor re: "Unique Intradural Inflammatory Mass Containing Precipitated Morphine" by Kim et al. Pain Pract. 2019 04; 19(4):456. Yaksh TL. PMID: 30614650.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Characterization of the antinociceptive effects of intrathecal DALDA peptides following bolus intrathecal delivery. Scand J Pain. 2019 01 28; 19(1):193-206. Kokubu S, Eddinger KA, Nguyen TM, Huerta-Esquivel LL, Yamaguchi S, Schiller PW, Yaksh TL. PMID: 30367811.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    51. Role of Toll-like receptor 4 signaling in mast cell-mediated migraine pain pathway. Mol Pain. 2019 Jan-Dec; 15:1744806919867842. Ramachandran R, Wang Z, Saavedra C, DiNardo A, Corr M, Powell SB, Yaksh TL. PMID: 31342858; PMCID: PMC6688145.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    52. Botulinum toxin blocks mast cells and prevents rosacea like inflammation. J Dermatol Sci. 2019 Jan; 93(1):58-64. Choi JE, Werbel T, Wang Z, Wu CC, Yaksh TL, Di Nardo A. PMID: 30658871; PMCID: PMC7680644.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    53. Spinal Exparel®-an extended duration of preclinical study needed. Br J Anaesth. 2019 03; 122(3):298-300. Eisenach JC, Yaksh TL. PMID: 30770045.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    54. Development of New Analgesics: An Answer to Opioid Epidemic. Trends Pharmacol Sci. 2018 12; 39(12):1000-1002. Yaksh TL, Hunt MA, Dos Santos GG. PMID: 30454767.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    55. Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug-unresponsive hyperalgesia in male rats. Pain. 2018 Dec; 159(12):2620-2629. Gregus AM, Buczynski MW, Dumlao DS, Norris PC, Rai G, Simeonov A, Maloney DJ, Jadhav A, Xu Q, Wei SC, Fitzsimmons BL, Dennis EA, Yaksh TL. PMID: 30130298; PMCID: PMC6237621.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    56. Neuraxial TNF and IFN-beta co-modulate persistent allodynia in arthritic mice. Brain Behav Immun. 2019 02; 76:151-158. Woller SA, Ocheltree C, Wong SY, Bui A, Fujita Y, Gonçalves Dos Santos G, Yaksh TL, Corr M. PMID: 30465880; PMCID: PMC6396982.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    57. Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome. Mol Pain. 2018 Jan-Dec; 14:1744806918815005. Shubayev VI, Strongin AY, Yaksh TL. PMID: 30392459; PMCID: PMC6287297.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    58. Targeting toll-like receptor-4 (TLR4)-an emerging therapeutic target for persistent pain states. Pain. 2018 Oct; 159(10):1908-1915. Bruno K, Woller SA, Miller YI, Yaksh TL, Wallace M, Beaton G, Chakravarthy K. PMID: 29889119; PMCID: PMC7890571.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    59. Transition to chronic pain: opportunities for novel therapeutics. Nat Rev Neurosci. 2018 07; 19(7):383-384. Price TJ, Basbaum AI, Bresnahan J, Chambers JF, De Koninck Y, Edwards RR, Ji RR, Katz J, Kavelaars A, Levine JD, Porter L, Schechter N, Sluka KA, Terman GW, Wager TD, Yaksh TL, Dworkin RH. PMID: 29765159; PMCID: PMC6237656.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    60. Inhibition of Neuroinflammation by AIBP: Spinal Effects upon Facilitated Pain States. Cell Rep. 2018 05 29; 23(9):2667-2677. Woller SA, Choi SH, An EJ, Low H, Schneider DA, Ramachandran R, Kim J, Bae YS, Sviridov D, Corr M, Yaksh TL, Miller YI. PMID: 29847797; PMCID: PMC6239868.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    61. Complexity of systems and actions underlying neurogenic inflammation. Semin Immunopathol. 2018 05; 40(3):225-228. Yaksh TL, Di Nardo A. PMID: 29779134.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    62. Rapid continuous 3D printing of customizable peripheral nerve guidance conduits. Mater Today (Kidlington). 2018 Nov; 21(9):951-959. Zhu W, Tringale KR, Woller SA, You S, Johnson S, Shen H, Schimelman J, Whitney M, Steinauer J, Xu W, Yaksh TL, Nguyen QT, Chen S. PMID: 31156331; PMCID: PMC6538503.
      View in: PubMed   Mentions: 57  
    63. A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus. Toxins (Basel). 2018 03 23; 10(4). Ramachandran R, Marino MJ, Paul S, Wang Z, Mascarenhas NL, Pellett S, Johnson EA, DiNardo A, Yaksh TL. PMID: 29570628; PMCID: PMC5923300.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    64. Origins of antidromic activity in sensory afferent fibers and neurogenic inflammation. Semin Immunopathol. 2018 May; 40(3):237-247. Sorkin LS, Eddinger KA, Woller SA, Yaksh TL. PMID: 29423889; PMCID: PMC7879713.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    65. An overview of pathways encoding nociception. Clin Exp Rheumatol. 2018 Jan-Feb; 36(1):172. Woller SA, Eddinger KA, Corr M, Yaksh TL. PMID: 29461960.
      View in: PubMed   Mentions: 9     Fields:    
    66. Corrigendum to "Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state" [Brain Behav. Immun. 56 (2016) 271-280]. Brain Behav Immun. 2018 03; 69:632. Woller SA, Ravula SB, Tucci FC, Beaton G, Corr M, Isseroff RR, Soulika AM, Chigbrow M, Eddinger KA, Yaksh TL. PMID: 29291934; PMCID: PMC6814394.
      View in: PubMed   Mentions:    Fields:    
    67. Toxicology Evaluation of Drugs Administered via Uncommon Routes: Intranasal, Intraocular, Intrathecal/Intraspinal, and Intra-Articular. Int J Toxicol. 2018 Jan/Feb; 37(1):4-27. Emami A, Tepper J, Short B, Yaksh TL, Bendele AM, Ramani T, Cisternas AF, Chang JH, Mellon RD. PMID: 29264927; PMCID: PMC5874330.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    68. Target engagement and histopathology of neuraxial resiniferatoxin in dog. Vet Anaesth Analg. 2018 Mar; 45(2):212-226. Hockman TM, Cisternas AF, Jones B, Butt MT, Osborn KG, Steinauer JJ, Malkmus SA, Yaksh TL. PMID: 29361418.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    69. Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics. Anesth Analg. 2017 11; 125(5):1714-1732. Knezevic NN, Yekkirala A, Yaksh TL. PMID: 29049116; PMCID: PMC5679134.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    70. Effects of opioid and nonopioid analgesics on canine wheal formation and cultured human mast cell degranulation. Toxicol Appl Pharmacol. 2018 01 01; 338:54-64. Schmidt-Rondon E, Wang Z, Malkmus SA, Di Nardo A, Hildebrand K, Page L, Yaksh TL. PMID: 29111148; PMCID: PMC9841896.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    71. An overview of pathways encoding nociception. Clin Exp Rheumatol. 2017 Sep-Oct; 35 Suppl 107(5):40-46. Woller SA, Eddinger KA, Corr M, Yaksh TL. PMID: 28967373; PMCID: PMC6636838.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    72. Editor's Highlight: Formulation and Toxicology Evaluation of the Intrathecal AYX1 DNA-Decoy in Sprague Dawley Rats. Toxicol Sci. 2017 09 01; 159(1):76-85. Mamet J, Yeomans DC, Yaksh TL, Manning DC, Harris S. PMID: 28903493.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    73. Modeling Spinal Intrathecal Drug Distribution: The Challenge of Defining and Predicting Cerebrospinal Fluid Dynamics. Anesth Analg. 2017 05; 124(5):1403-1406. Bert RJ, Hayek SM, Yaksh TL. PMID: 28426585.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    74. Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents. J Pain. 2017 10; 18(10):1184-1196. Yaksh TL, Schwarcz R, Snodgrass HR. PMID: 28428091.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    75. Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model. Scand J Pain. 2017 07; 16:1-9. Rijsdijk M, Agalave NM, van Wijck AJM, Kalkman CJ, Ramachandran R, Baharpoor A, Svensson CI, Yaksh TL. PMID: 28850381.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    76. Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor. Sci Rep. 2017 01 03; 7:39662. Flinspach M, Xu Q, Piekarz AD, Fellows R, Hagan R, Gibbs A, Liu Y, Neff RA, Freedman J, Eckert WA, Zhou M, Bonesteel R, Pennington MW, Eddinger KA, Yaksh TL, Hunter M, Swanson RV, Wickenden AD. PMID: 28045073; PMCID: PMC5206724.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    77. The Polyanalgesic Consensus Conference (PACC): Recommendations for Intrathecal Drug Delivery: Guidance for Improving Safety and Mitigating Risks. Neuromodulation. 2017 Feb; 20(2):155-176. Deer TR, Pope JE, Hayek SM, Lamer TJ, Veizi IE, Erdek M, Wallace MS, Grider JS, Levy RM, Prager J, Rosen SM, Saulino M, Yaksh TL, De Andrés JA, Abejon Gonzalez D, Vesper J, Schu S, Simpson B, Mekhail N. PMID: 28042914.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    78. The Polyanalgesic Consensus Conference (PACC): Recommendations on Intrathecal Drug Infusion Systems Best Practices and Guidelines. Neuromodulation. 2017 02; 20(2):96-132. Deer TR, Pope JE, Hayek SM, Bux A, Buchser E, Eldabe S, De Andrés JA, Erdek M, Patin D, Grider JS, Doleys DM, Jacobs MS, Yaksh TL, Poree L, Wallace MS, Prager J, Rauck R, DeLeon O, Diwan S, Falowski SM, Gazelka HM, Kim P, Leong M, Levy RM, McDowell G, McRoberts P, Naidu R, Narouze S, Perruchoud C, Rosen SM, Rosenberg WS, Saulino M, Staats P, Stearns LJ, Willis D, Krames E, Huntoon M, Mekhail N. PMID: 28042904.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    79. Pharmacology, pharmacokinetics, and metabolism of the DNA-decoy AYX1 for the prevention of acute and chronic post-surgical pain. Mol Pain. 2017 01; 13:1744806917703112. Mamet J, Harris S, Klukinov M, Yeomans DC, Donahue RR, Taylor BK, Eddinger K, Yaksh T, Manning DC. PMID: 28394696; PMCID: PMC5407669.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    80. Current and Future Issues in the Development of Spinal Agents for the Management of Pain. Curr Neuropharmacol. 2017; 15(2):232-259. Yaksh TL, Fisher CJ, Hockman TM, Wiese AJ. PMID: 26861470; PMCID: PMC5412694.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    81. Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain. Brain Behav Immun. 2017 Feb; 60:282-292. Hong S, Remacle AG, Shiryaev SA, Choi W, Hullugundi SK, Dolkas J, Angert M, Nishihara T, Yaksh TL, Strongin AY, Shubayev VI. PMID: 27833045; PMCID: PMC5214638.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    82. Ethical Concerns Regarding Human Study. CNS Neurosci Ther. 2016 10; 22(10):866. Eisenach JC, Yaksh TL. PMID: 27577599; PMCID: PMC6492918.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    83. Primary Hydromorphone-Related Intrathecal Catheter Tip Granulomas: Is There a Role for Dose and Concentration? Neuromodulation. 2016 Oct; 19(7):760-769. Veizi IE, Hayek SM, Hanes M, Galica R, Katta S, Yaksh T. PMID: 27505059.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    84. Intrathecal Catheterization and Drug Delivery in Guinea Pigs: A Small-animal Model for Morphine-evoked Granuloma Formation. Anesthesiology. 2016 08; 125(2):378-94. Eddinger KA, Rondon ES, Shubayev VI, Grafe MR, Scadeng M, Hildebrand KR, Page LM, Malkmus SA, Steinauer JJ, Yaksh TL. PMID: 27272672.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    85. Role of myelin auto-antigens in pain: a female connection. Neural Regen Res. 2016 Jun; 11(6):890-1. Shubayev VI, Strongin AY, Yaksh TL. PMID: 27482203; PMCID: PMC4962572.
      View in: PubMed   Mentions: 14  
    86. Effects of intraplantar botulinum toxin-B on carrageenan-induced changes in nociception and spinal phosphorylation of GluA1 and Akt. Eur J Neurosci. 2016 07; 44(1):1714-22. Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS, Ramachandran R. PMID: 27108664; PMCID: PMC4931962.
      View in: PubMed   Mentions: 3  Translation:AnimalsCells
    87. Identification of Psychoactive Degradants of Cannabidiol in Simulated Gastric and Physiological Fluid. Cannabis Cannabinoid Res. 2016; 1(1):102-112. Merrick J, Lane B, Sebree T, Yaksh T, O'Neill C, Banks SL. PMID: 28861485; PMCID: PMC5576596.
      View in: PubMed   Mentions: 34     Fields:    
    88. Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state. Brain Behav Immun. 2016 08; 56:271-80. Woller SA, Ravula SB, Tucci FC, Beaton G, Corr M, Isseroff RR, Soulika AM, Chigbrow M, Eddinger KA, Yaksh TL. PMID: 27044335; PMCID: PMC4917460.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    89. Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia. Brain Behav Immun. 2016 Aug; 56:378-89. Ko JS, Eddinger KA, Angert M, Chernov AV, Dolkas J, Strongin AY, Yaksh TL, Shubayev VI. PMID: 26970355; PMCID: PMC4917441.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    90. The Emerging Role of Spinal Dynorphin in Chronic Pain: A Therapeutic Perspective. Annu Rev Pharmacol Toxicol. 2016; 56:511-33. Podvin S, Yaksh T, Hook V. PMID: 26738478; PMCID: PMC4902163.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    91. Analgesic properties of intrathecal glucocorticoids in three well established preclinical pain models. Scand J Pain. 2016 01; 10:90-102. Rijsdijk M, Svensson CI, van Wijck AJ, Kalkman CJ, Yaksh TL. PMID: 28361779.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    92. Current status and future directions of botulinum neurotoxins for targeting pain processing. Toxins (Basel). 2015 Nov 04; 7(11):4519-63. Pellett S, Yaksh TL, Ramachandran R. PMID: 26556371; PMCID: PMC4663519.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    93. The effect of gabapentin and ketorolac on allodynia and conditioned place preference in antibody-induced inflammation. Eur J Pain. 2016 07; 20(6):917-25. Park HJ, Sandor K, McQueen J, Woller SA, Svensson CI, Corr M, Yaksh TL. PMID: 26517300; PMCID: PMC5986296.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    94. The effects of intraplantar and intrathecal botulinum toxin type B on tactile allodynia in mono and polyneuropathy in the mouse. Anesth Analg. 2015 Jul; 121(1):229-238. Park HJ, Marino MJ, Rondon ES, Xu Q, Yaksh TL. PMID: 26039418.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    95. The search for novel analgesics: targets and mechanisms. F1000Prime Rep. 2015; 7:56. Yaksh TL, Woller SA, Ramachandran R, Sorkin LS. PMID: 26097729; PMCID: PMC4447049.
      View in: PubMed   Mentions: 44  
    96. Botulinum toxin in migraine: Role of transport in trigemino-somatic and trigemino-vascular afferents. Neurobiol Dis. 2015 Jul; 79:111-22. Ramachandran R, Lam C, Yaksh TL. PMID: 25958249; PMCID: PMC4458441.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    97. Differences in cisplatin-induced mechanical allodynia in male and female mice. Eur J Pain. 2015 Nov; 19(10):1476-85. Woller SA, Corr M, Yaksh TL. PMID: 25716290; PMCID: PMC4755718.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    98. High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs. Gene Ther. 2015 Feb; 22(2):202-8. Pleticha J, Malkmus SA, Heilmann LF, Veesart SL, Rezek R, Xu Q, Yaksh TL, Beutler AS. PMID: 25354684; PMCID: PMC5079622.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    99. Therapeutic use of botulinum toxin in migraine: mechanisms of action. Br J Pharmacol. 2014 Sep; 171(18):4177-92. Ramachandran R, Yaksh TL. PMID: 24819339; PMCID: PMC4241086.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    100. Spinal release of tumour necrosis factor activates c-Jun N-terminal kinase and mediates inflammation-induced hypersensitivity. Eur J Pain. 2015 Feb; 19(2):260-70. Bas DB, Abdelmoaty S, Sandor K, Codeluppi S, Fitzsimmons B, Steinauer J, Hua XY, Yaksh TL, Svensson CI. PMID: 24942612; PMCID: PMC4270961.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    101. The effects of glucocorticoids on neuropathic pain: a review with emphasis on intrathecal methylprednisolone acetate delivery. Anesth Analg. 2014 May; 118(5):1097-112. Rijsdijk M, van Wijck AJ, Kalkman CJ, Yaksh TL. PMID: 24781577.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    102. TRPV1 expression regulation… A further step in defining its biology: commentary for K. Zavala et al. "The anticancer antibiotic mithramycin-A inhibits TRPV1 expression in dorsal root ganglion neurons" [Neurosci. Lett. (2014) doi:10.1016/j.neulet.2014.01.021]. Neurosci Lett. 2014 Aug 22; 578:209-10. Yaksh TL. PMID: 24769421.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    103. Preclinical toxicity screening of intrathecal oxytocin in rats and dogs. Anesthesiology. 2014 Apr; 120(4):951-61. Yaksh TL, Hobo S, Peters C, Osborn KG, Richter PJ, Rossi SS, Grafe MR, Eisenach JC. PMID: 24492326; PMCID: PMC5392224.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    104. Supraspinal characterization of the thermal grill illusion with fMRI. Mol Pain. 2014 Mar 11; 10:18. Leung A, Shukla S, Li E, Duann JR, Yaksh T. PMID: 24612493; PMCID: PMC3995740.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    105. Spinal cord ischemia/injury. Curr Pharm Des. 2014; 20(36):5738-43. Ishikawa T, Suzuki H, Ishikawa K, Yasuda S, Matsui T, Yamamoto M, Kakeda T, Yamamoto S, Owada Y, Yaksh TL. PMID: 24502574.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    106. Botulinum toxin B in the sensory afferent: transmitter release, spinal activation, and pain behavior. Pain. 2014 Apr; 155(4):674-684. Marino MJ, Terashima T, Steinauer JJ, Eddinger KA, Yaksh TL, Xu Q. PMID: 24333775; PMCID: PMC3960322.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    107. Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice. J Neuroinflammation. 2013 Dec 09; 10:148. Stokes JA, Cheung J, Eddinger K, Corr M, Yaksh TL. PMID: 24321498; PMCID: PMC3896749.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    108. Intrathecal substance P-saporin in the dog: distribution, safety, and spinal neurokinin-1 receptor ablation. Anesthesiology. 2013 Nov; 119(5):1163-77. Wiese AJ, Rathbun M, Butt MT, Malkmus SA, Richter PJ, Osborn KG, Xu Q, Veesart SL, Steinauer JJ, Higgins D, Lappi DA, Russell B, Yaksh TL. PMID: 24051388.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    109. Toll-like receptor signaling regulates cisplatin-induced mechanical allodynia in mice. Cancer Chemother Pharmacol. 2014 Jan; 73(1):25-34. Park HJ, Stokes JA, Corr M, Yaksh TL. PMID: 24162377; PMCID: PMC3917999.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    110. Single intrathecal administration of the transcription factor decoy AYX1 prevents acute and chronic pain after incisional, inflammatory, or neuropathic injury. Pain. 2014 Feb; 155(2):322-333. Mamet J, Klukinov M, Yaksh TL, Malkmus SA, Williams S, Harris S, Manning DC, Taylor BK, Donahue RR, Porreca F, Xie JY, Oyarzo J, Brennan TJ, Subieta A, Schmidt WK, Yeomans DC. PMID: 24145208.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    111. Effects of intrathecal SNC80, a delta receptor ligand, on nociceptive threshold and dorsal horn substance p release. J Pharmacol Exp Ther. 2013 Nov; 347(2):258-64. Kouchek M, Takasusuki T, Terashima T, Yaksh TL, Xu Q. PMID: 23978562; PMCID: PMC3807063.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    112. Neuroscience: Bacteria get on your nerves. Nature. 2013 Sep 05; 501(7465):43-4. Nizet V, Yaksh T. PMID: 23965630.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    113. Effects of general anesthetics on substance P release and c-Fos expression in the spinal dorsal horn. Anesthesiology. 2013 Aug; 119(2):433-42. Takasusuki T, Yamaguchi S, Hamaguchi S, Yaksh TL. PMID: 23708866; PMCID: PMC3788114.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    114. Evaluation of spinal toxicity and long-term spinal reflex function after intrathecal levobupivaciane in the neonatal rat. Anesthesiology. 2013 Jul; 119(1):142-55. Hamurtekin E, Fitzsimmons BL, Shubayev VI, Grafe MR, Deumens R, Yaksh TL, Walker SM. PMID: 23514721; PMCID: PMC3732172.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    115. Intrathecal P/Q- and R-type calcium channel blockade of spinal substance P release and c-Fos expression. Neuropharmacology. 2013 Dec; 75:1-8. Terashima T, Xu Q, Yamaguchi S, Yaksh TL. PMID: 23810829; PMCID: PMC3865027.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    116. Intrathecal neurosteroids and a neurosteroid antagonist: effects on inflammation-evoked thermal hyperalgesia and tactile allodynia. Neurosci Lett. 2013 Aug 26; 548:27-32. Svensson E, Persson J, Fitzsimmons B, Yaksh TL. PMID: 23707652; PMCID: PMC3761066.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    117. Role of meningeal mast cells in intrathecal morphine-evoked granuloma formation. Anesthesiology. 2013 Mar; 118(3):664-78. Yaksh TL, Allen JW, Veesart SL, Horais KA, Malkmus SA, Scadeng M, Steinauer JJ, Rossi SS. PMID: 23426209; PMCID: PMC3788115.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    118. Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia. FASEB J. 2013 May; 27(5):1939-49. Gregus AM, Dumlao DS, Wei SC, Norris PC, Catella LC, Meyerstein FG, Buczynski MW, Steinauer JJ, Fitzsimmons BL, Yaksh TL, Dennis EA. PMID: 23382512; PMCID: PMC3633813.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    119. Spinal toll-like receptor signaling and nociceptive processing: regulatory balance between TIRAP and TRIF cascades mediated by TNF and IFNβ. Pain. 2013 May; 154(5):733-742. Stokes JA, Corr M, Yaksh TL. PMID: 23489833; PMCID: PMC3622773.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    120. Spinal astrocytes produce and secrete dynorphin neuropeptides. Neuropeptides. 2013 Apr; 47(2):109-15. Wahlert A, Funkelstein L, Fitzsimmons B, Yaksh T, Hook V. PMID: 23290538; PMCID: PMC3606903.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    121. Persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root ganglia activated transcription factor 3: the effects of gabapentin, ketorolac, and etanercept. Anesth Analg. 2013 Jan; 116(1):224-31. Park HJ, Stokes JA, Pirie E, Skahen J, Shtaerman Y, Yaksh TL. PMID: 23223118; PMCID: PMC3530135.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    122. Alfentanil: correlations between absence of effect upon subcutaneous mast cells and absence of granuloma formation after intrathecal infusion in the dog. Neuromodulation. 2013 Sep-Oct; 16(5):459-66; discussion 466. Yaksh TL, Steinauer JJ, Veesart SL, Malkmus SA. PMID: 23170763; PMCID: PMC3582801.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    123. Development and validation of an automated system for detection and assessment of scratching in the rodent. J Neurosci Methods. 2012 Oct 15; 211(1):1-10. Marino M, Huang P, Malkmus S, Robertshaw E, Mac EA, Shatterman Y, Yaksh TL. PMID: 22971351; PMCID: PMC3473159.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    124. Polyanalgesic Consensus Conference--2012: recommendations to reduce morbidity and mortality in intrathecal drug delivery in the treatment of chronic pain. Neuromodulation. 2012 Sep-Oct; 15(5):467-82; discussion 482. Deer TR, Levy R, Prager J, Buchser E, Burton A, Caraway D, Cousins M, De Andrés J, Diwan S, Erdek M, Grigsby E, Huntoon M, Jacobs MS, Kim P, Kumar K, Leong M, Liem L, McDowell GC, Panchal S, Rauck R, Saulino M, Sitzman BT, Staats P, Stanton-Hicks M, Stearns L, Wallace M, Willis KD, Witt W, Yaksh T, Mekhail N. PMID: 22849581.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    125. Characteristics of distribution of morphine and metabolites in cerebrospinal fluid and plasma with chronic intrathecal morphine infusion in humans. Anesth Analg. 2012 Oct; 115(4):797-804. Wallace M, Yaksh TL. PMID: 22822192; PMCID: PMC3456964.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    126. Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12728-33. Lampa J, Westman M, Kadetoff D, Agréus AN, Le Maître E, Gillis-Haegerstrand C, Andersson M, Khademi M, Corr M, Christianson CA, Delaney A, Yaksh TL, Kosek E, Svensson CI. PMID: 22802629; PMCID: PMC3411968.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCTClinical Trials
    127. Neuraxial analgesia in neonates and infants: a review of clinical and preclinical strategies for the development of safety and efficacy data. Anesth Analg. 2012 Sep; 115(3):638-62. Walker SM, Yaksh TL. PMID: 22798528; PMCID: PMC4451199.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    128. Polyanalgesic Consensus Conference 2012: recommendations for the management of pain by intrathecal (intraspinal) drug delivery: report of an interdisciplinary expert panel. Neuromodulation. 2012 Sep-Oct; 15(5):436-64; discussion 464-6. Deer TR, Prager J, Levy R, Rathmell J, Buchser E, Burton A, Caraway D, Cousins M, De Andrés J, Diwan S, Erdek M, Grigsby E, Huntoon M, Jacobs MS, Kim P, Kumar K, Leong M, Liem L, McDowell GC, Panchal S, Rauck R, Saulino M, Sitzman BT, Staats P, Stanton-Hicks M, Stearns L, Wallace M, Willis KD, Witt W, Yaksh T, Mekhail N. PMID: 22748024.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    129. Pharmacokinetic analysis of ziconotide (SNX-111), an intrathecal N-type calcium channel blocking analgesic, delivered by bolus and infusion in the dog. Neuromodulation. 2012 Nov-Dec; 15(6):508-19; discussion 519. Yaksh TL, de Kater A, Dean R, Best BM, Miljanich GP. PMID: 22748108; PMCID: PMC3514653.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    130. Perineural local anesthetic and adjuvant action: the meaning of an ex vivo data set for efficacy and safety. Reg Anesth Pain Med. 2012 Jul-Aug; 37(4):366-8. Yaksh TL, Ilfeld BM, Wiese AJ. PMID: 22660488.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    131. Epidural steroids, etanercept, or saline in subacute sciatica: a multicenter, randomized trial. Ann Intern Med. 2012 Apr 17; 156(8):551-9. Cohen SP, White RL, Kurihara C, Larkin TM, Chang A, Griffith SR, Gilligan C, Larkin R, Morlando B, Pasquina PF, Yaksh TL, Nguyen C. PMID: 22508732.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    132. Polyanalgesic Consensus Conference--2012: consensus on diagnosis, detection, and treatment of catheter-tip granulomas (inflammatory masses). Neuromodulation. 2012 Sep-Oct; 15(5):483-95; discussion 496. Deer TR, Prager J, Levy R, Rathmell J, Buchser E, Burton A, Caraway D, Cousins M, De Andrés J, Diwan S, Erdek M, Grigsby E, Huntoon M, Jacobs MS, Kim P, Kumar K, Leong M, Liem L, McDowell GC, Panchal S, Rauck R, Saulino M, Sitzman BT, Staats P, Stanton-Hicks M, Stearns L, Wallace M, Willis KD, Witt W, Yaksh T, Mekhail N. PMID: 22494332.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    133. Polyanalgesic Consensus Conference--2012: recommendations on trialing for intrathecal (intraspinal) drug delivery: report of an interdisciplinary expert panel. Neuromodulation. 2012 Sep-Oct; 15(5):420-35; discussion 435. Deer TR, Prager J, Levy R, Burton A, Buchser E, Caraway D, Cousins M, De Andrés J, Diwan S, Erdek M, Grigsby E, Huntoon M, Jacobs M, Kim P, Kumar K, Leong M, Liem L, McDowell G, Panchal SJ, Rauck R, Saulino M, Staats P, Stanton-Hicks M, Stearns L, Sitzman BT, Wallace M, Willis KD, Witt W, Yaksh T, Mekhail N. PMID: 22494357.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    134. Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17):6721-6. Gregus AM, Doolen S, Dumlao DS, Buczynski MW, Takasusuki T, Fitzsimmons BL, Hua XY, Taylor BK, Dennis EA, Yaksh TL. PMID: 22493235; PMCID: PMC3340022.
      View in: PubMed   Mentions: 69     Fields:    Translation:Animals
    135. Intrathecal clonidine in the neonatal rat: dose-dependent analgesia and evaluation of spinal apoptosis and toxicity. Anesth Analg. 2012 Aug; 115(2):450-60. Walker SM, Grafe M, Yaksh TL. PMID: 22467896; PMCID: PMC4455964.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    136. Safety assessment and pharmacokinetics of intrathecal methylprednisolone acetate in dogs. Anesthesiology. 2012 Jan; 116(1):170-81. Rijsdijk M, van Wijck AJ, Kalkman CJ, Meulenhoff PC, Grafe MR, Steinauer J, Yaksh TL. PMID: 22139590.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    137. K/BxN serum transfer arthritis as a model of inflammatory joint pain. Methods Mol Biol. 2012; 851:249-60. Christianson CA, Corr M, Yaksh TL, Svensson CI. PMID: 22351097; PMCID: PMC5426904.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    138. Effects of long term polyarthritis and subsequent NSAID treatment on activity with disassociation of tactile allodynia in the mouse. Neurocomputing (Amst). 2012 May 01; 84:47-52. Suhail MS, Christianson C, Koehrn F, Malkmus SA, Mitchell W, Corr M, Yaksh TL. PMID: 22547902; PMCID: PMC3338856.
      View in: PubMed   Mentions: 2  
    139. Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis. Pain. 2011 Dec; 152(12):2881-2891. Christianson CA, Dumlao DS, Stokes JA, Dennis EA, Svensson CI, Corr M, Yaksh TL. PMID: 22019135; PMCID: PMC3347973.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    140. Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a tumor necrosis factor-dependent mechanism. Neuroscience. 2012 Jan 03; 200:199-210. Christianson CA, Fitzsimmons BL, Shim JH, Agrawal A, Cohen SM, Hua XY, Yaksh TL. PMID: 22056600; PMCID: PMC3346277.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    141. The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats. J Anesth. 2011 Dec; 25(6):884-91. Kim HJ, Seol TK, Lee HJ, Yaksh TL, Jun JH. PMID: 21983967.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    142. Transient tactile allodynia following intrathecal puncture in mouse: contributions of Toll-like receptor signaling. Neurosci Lett. 2011 Oct 31; 504(3):215-8. Stokes JA, Corr M, Yaksh TL. PMID: 21964382; PMCID: PMC3338641.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    143. Potent suppression of stretch reflex activity after systemic or spinal delivery of tizanidine in rats with spinal ischemia-induced chronic spastic paraplegia. Neuroscience. 2011 Oct 27; 194:160-9. Fuchigami T, Kakinohana O, Hefferan MP, Lukacova N, Marsala S, Platoshyn O, Sugahara K, Yaksh TL, Marsala M. PMID: 21871540; PMCID: PMC3192017.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    144. A brief comparison of the pathophysiology of inflammatory versus neuropathic pain. Curr Opin Anaesthesiol. 2011 Aug; 24(4):400-7. Xu Q, Yaksh TL. PMID: 21659872; PMCID: PMC3290396.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    145. Care to wrestle with a Brazilian armed spider? Pain. 2011 Oct; 152(10):2193-2195. Yaksh TL. PMID: 21782344.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    146. Spinal toxins can have persistent adverse effects. Pain Med. 2011 Jul; 12(7):991-2. Yaksh TL. PMID: 21752177.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    147. Regulation of spinal substance p release by intrathecal calcium channel blockade. Anesthesiology. 2011 Jul; 115(1):153-64. Takasusuki T, Yaksh TL. PMID: 21577088; PMCID: PMC3360553.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    148. Spinal botulinum neurotoxin B: effects on afferent transmitter release and nociceptive processing. PLoS One. 2011 Apr 29; 6(4):e19126. Huang PP, Khan I, Suhail MS, Malkmus S, Yaksh TL. PMID: 21559464; PMCID: PMC3084763.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    149. The effects of intrathecal and systemic gabapentin on spinal substance P release. Anesth Analg. 2011 Apr; 112(4):971-6. Takasusuki T, Yaksh TL. PMID: 21385982; PMCID: PMC3347974.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    150. Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia. J Neurosci. 2011 Feb 09; 31(6):2113-24. Xu Q, Fitzsimmons B, Steinauer J, O'Neill A, Newton AC, Hua XY, Yaksh TL. PMID: 21307248; PMCID: PMC3097059.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    151. Suppression of stretch reflex activity after spinal or systemic treatment with AMPA receptor antagonist NGX424 in rats with developed baclofen tolerance. Br J Pharmacol. 2010 Nov; 161(5):976-85. Oshiro M, Hefferan MP, Kakinohana O, Lukacova N, Sugahara K, Yaksh TL, Marsala M. PMID: 20977450; PMCID: PMC2998680.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    152. Recommendations for the use of preclinical models in the study and treatment of osteoarthritis. Osteoarthritis Cartilage. 2010 Oct; 18 Suppl 3:S10-6. Poole R, Blake S, Buschmann M, Goldring S, Laverty S, Lockwood S, Matyas J, McDougall J, Pritzker K, Rudolphi K, van den Berg W, Yaksh T. PMID: 20864015.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    153. Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis. Pain. 2010 Nov; 151(2):394-403. Christianson CA, Corr M, Firestein GS, Mobargha A, Yaksh TL, Svensson CI. PMID: 20739123; PMCID: PMC2955775.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    154. Spinal glial TLR4-mediated nociception and production of prostaglandin E(2) and TNF. Br J Pharmacol. 2010 Aug; 160(7):1754-64. Saito O, Svensson CI, Buczynski MW, Wegner K, Hua XY, Codeluppi S, Schaloske RH, Deems RA, Dennis EA, Yaksh TL. PMID: 20649577; PMCID: PMC2936846.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    155. Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. Brain Res. 2010 Sep 17; 1352:83-93. Peters CM, Hayashida K, Ewan EE, Nakajima K, Obata H, Xu Q, Yaksh TL, Eisenach JC. PMID: 20637741; PMCID: PMC2943762.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    156. Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase. Anesth Analg. 2010 Aug; 111(2):554-60. Matsui T, Svensson CI, Hirata Y, Mizobata K, Hua XY, Yaksh TL. PMID: 20610553.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    157. Effects of intrathecal ketamine in the neonatal rat: evaluation of apoptosis and long-term functional outcome. Anesthesiology. 2010 Jul; 113(1):147-59. Walker SM, Westin BD, Deumens R, Grafe M, Yaksh TL. PMID: 20526188; PMCID: PMC2904694.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    158. Validation of a preclinical spinal safety model: effects of intrathecal morphine in the neonatal rat. Anesthesiology. 2010 Jul; 113(1):183-99. Westin BD, Walker SM, Deumens R, Grafe M, Yaksh TL. PMID: 20526189; PMCID: PMC2902725.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    159. Assessment of canine sensory function by using sine-wave electrical stimuli paradigm. Physiol Behav. 2010 Oct 05; 101(3):327-30. Watabiki T, Nagakura Y, Wegner K, Kakimoto S, Tozier NA, Malkmus SA, Yaksh TL. PMID: 20570687.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    160. Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord. J Neurochem. 2010 Aug; 114(4):981-93. Buczynski MW, Svensson CI, Dumlao DS, Fitzsimmons BL, Shim JH, Scherbart TJ, Jacobsen FE, Hua XY, Yaksh TL, Dennis EA. PMID: 20492349; PMCID: PMC3994888.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    161. Effects of intrathecal ketorolac on human experimental pain. Anesthesiology. 2010 May; 112(5):1216-24. Eisenach JC, Curry R, Tong C, Houle TT, Yaksh TL. PMID: 20395821; PMCID: PMC2924167.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    162. Role of spinal cyclooxygenase in human postoperative and chronic pain. Anesthesiology. 2010 May; 112(5):1225-33. Eisenach JC, Curry R, Rauck R, Pan P, Yaksh TL. PMID: 20395820; PMCID: PMC2892621.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    163. Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs. Cell Transplant. 2010; 19(9):1103-22. Usvald D, Vodicka P, Hlucilova J, Prochazka R, Motlik J, Kuchorova K, Johe K, Marsala S, Scadeng M, Kakinohana O, Navarro R, Santa M, Hefferan MP, Yaksh TL, Marsala M. PMID: 20412634.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    164. Consent contraindicated? Science. 2010 Apr 02; 328(5974):45; author reply 45. Yaksh TL, Eisenach JC, Shafer SL. PMID: 20360092.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    165. The need for a journal policy on intrathecal, epidural, and perineural administration of non-approved drugs. Pain. 2010 Jun; 149(3):417-419. Eisenach JC, Shafer SL, Yaksh T. PMID: 20227830.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    166. Role of spinal p38alpha and beta MAPK in inflammatory hyperalgesia and spinal COX-2 expression. Neuroreport. 2010 Mar 10; 21(4):313-7. Fitzsimmons BL, Zattoni M, Svensson CI, Steinauer J, Hua XY, Yaksh TL. PMID: 20134354; PMCID: PMC2877130.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    167. Correlation between myoclonus and the 3-glucuronide metabolites in patients treated with morphine or hydromorphone: a pilot study. J Opioid Manag. 2010 Mar-Apr; 6(2):87-94. McCann S, Yaksh TL, von Gunten CF. PMID: 20481173.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    168. [Vacuoles: a hollow threat?]. Can J Anaesth. 2010 Mar; 57(3):195-200. Yaksh TL. PMID: 20054677; PMCID: PMC2821579.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    169. Preclinical research on persistent postsurgical pain: what we don't know, but should start studying. Anesthesiology. 2010 Mar; 112(3):511-3. Scholz J, Yaksh TL. PMID: 20124975; PMCID: PMC2828501.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    170. Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats. Neurosci Lett. 2010 Feb 05; 470(1):6-9. Park P, Schachter S, Yaksh T. PMID: 20026382; PMCID: PMC2834555.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    171. Behavioral models of pain states evoked by physical injury to the peripheral nerve. Neurotherapeutics. 2009 Oct; 6(4):609-19. Sorkin LS, Yaksh TL. PMID: 19789066; PMCID: PMC5084283.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    172. New caudal additives in children: benefit vs. risk? Acta Anaesthesiol Scand. 2009 Sep; 53(8):1097-8; author reply 1098-9. Walker SM, Yaksh TL. PMID: 19694618.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    173. Randomized, double-blind, placebo-controlled, dose-response, and preclinical safety study of transforaminal epidural etanercept for the treatment of sciatica. Anesthesiology. 2009 May; 110(5):1116-26. Cohen SP, Bogduk N, Dragovich A, Buckenmaier CC, Griffith S, Kurihara C, Raymond J, Richter PJ, Williams N, Yaksh TL. PMID: 19387178.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    174. The end of postoperative pain--a fast-approaching possibility? And, if so, will we be ready? Reg Anesth Pain Med. 2009 Mar-Apr; 34(2):85-7. Ilfeld BM, Yaksh TL. PMID: 19282704.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    175. Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress. Gastroenterology. 2009 Apr; 136(4):1339-48, e1-2. Bradesi S, Svensson CI, Steinauer J, Pothoulakis C, Yaksh TL, Mayer EA. PMID: 19249394; PMCID: PMC2812027.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    176. Spinal antinociceptive action of loperamide is mediated by opioid receptors in the formalin test in rats. Neurosci Lett. 2008 Dec 31; 448(3):260-2. Ray SB, Yaksh TL. PMID: 18973791; PMCID: PMC2753543.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    177. Role of p38 mitogen activated protein kinase in a model of osteosarcoma-induced pain. Pharmacol Biochem Behav. 2008 Oct; 90(4):664-75. Svensson CI, Medicherla S, Malkmus S, Jiang Y, Ma JY, Kerr I, Brainin-Mattos J, Powell HC, Luo ZD, Chakravarty S, Dugar S, Higgins LS, Protter AA, Yaksh TL. PMID: 18584857.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    178. Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine. Br J Pharmacol. 2008 Dec; 155(7):1117-26. Nazarian A, Christianson CA, Hua XY, Yaksh TL. PMID: 18846040; PMCID: PMC2597249.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    179. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12599-604. Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. PMID: 18719118; PMCID: PMC2527957.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    180. The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy. Pain. 2008 Oct 31; 139(3):569-577. Nagakura Y, Jones TL, Malkmus SA, Sorkin L, Yaksh TL. PMID: 18692315; PMCID: PMC3346272.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    181. Acetaminophen prevents hyperalgesia in central pain cascade. Neurosci Lett. 2008 Sep 05; 442(1):50-3. Crawley B, Saito O, Malkmus S, Fitzsimmons B, Hua XY, Yaksh TL. PMID: 18601979; PMCID: PMC2669887.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    182. Toxicology profile of N-methyl-D-aspartate antagonists delivered by intrathecal infusion in the canine model. Anesthesiology. 2008 May; 108(5):938-49. Yaksh TL, Tozier N, Horais KA, Malkmus S, Rathbun M, Lafranco L, Eisenach J. PMID: 18431131.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    183. The effect of acupuncture duration on analgesia and peripheral sensory thresholds. BMC Complement Altern Med. 2008 May 01; 8:18. Leung AY, Kim SJ, Schulteis G, Yaksh T. PMID: 18452622; PMCID: PMC2386116.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    184. Inhibition of spinal cytosolic phospholipase A(2) expression by an antisense oligonucleotide attenuates tissue injury-induced hyperalgesia. Neuroscience. 2008 Jun 26; 154(3):1077-87. Kim DH, Fitzsimmons B, Hefferan MP, Svensson CI, Wancewicz E, Monia BP, Hung G, Butler M, Marsala M, Hua XY, Yaksh TL. PMID: 18511207; PMCID: PMC2640426.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    185. Spinal N-methyl-D-aspartate receptors and nociception-evoked release of primary afferent substance P. Neuroscience. 2008 Mar 03; 152(1):119-27. Nazarian A, Gu G, Gracias NG, Wilkinson K, Hua XY, Vasko MR, Yaksh TL. PMID: 18222611; PMCID: PMC2730522.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    186. Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. Neuropharmacology. 2008 Feb; 54(2):269-79. Khan IM, Wart CV, Singletary EA, Stanislaus S, Deerinck T, Yaksh TL, Printz MP. PMID: 18037142; PMCID: PMC4418974.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    187. Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity. J Neurosci. 2007 Oct 17; 27(42):11179-91. Hefferan MP, Kucharova K, Kinjo K, Kakinohana O, Sekerkova G, Nakamura S, Fuchigami T, Tomori Z, Yaksh TL, Kurtz N, Marsala M. PMID: 17942713; PMCID: PMC6673044.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    188. Development of a canine nociceptive thermal escape model. J Neurosci Methods. 2008 Feb 15; 168(1):88-97. Wegner K, Horais KA, Tozier NA, Rathbun ML, Shtaerman Y, Yaksh TL. PMID: 18054083; PMCID: PMC2266689.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCTClinical Trials
    189. Neonates have a spinal alpha receptor too, as do adults. Br J Pharmacol. 2007 Aug; 151(8):1139-40. Yaksh TL. PMID: 17641678; PMCID: PMC2189816.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    190. Mandating two-year regional anesthesia fellowships: fanning the academic flame or extinguishing it? Reg Anesth Pain Med. 2007 Jul-Aug; 32(4):275-9. Ilfeld BM, Yaksh TL, Neal JM. PMID: 17720109; PMCID: PMC2048748.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    191. Determination of current threshold for paw withdrawal with sine-wave electrical stimulation in rats: effect of drugs and alteration in acute inflammation. Pain. 2008 Feb; 134(3):293-301. Nagakura Y, Malkmus S, Yaksh TL. PMID: 17583428.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    192. An assessment of the antinociceptive efficacy of intrathecal and epidural contulakin-G in rats and dogs. Anesth Analg. 2007 Jun; 104(6):1505-13, table of contents. Allen JW, Hofer K, McCumber D, Wagstaff JD, Layer RT, McCabe RT, Yaksh TL. PMID: 17513650.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    193. The pharmacokinetics of the conopeptide contulakin-G (CGX-1160) after intrathecal administration: an analysis of data from studies in beagles. Anesth Analg. 2007 Jun; 104(6):1514-20, table of contents. Kern SE, Allen J, Wagstaff J, Shafer SL, Yaksh T. PMID: 17513651.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    194. Inhibition of spinal constitutive NOS-2 by 1400W attenuates tissue injury and inflammation-induced hyperalgesia and spinal p38 activation. Eur J Neurosci. 2007 May; 25(10):2964-72. Tang Q, Svensson CI, Fitzsimmons B, Webb M, Yaksh TL, Hua XY. PMID: 17561811.
      View in: PubMed   Mentions: 19  Translation:AnimalsCells
    195. Descending serotonergic facilitation of spinal ERK activation and pain behavior. FEBS Lett. 2006 Dec 11; 580(28-29):6629-34. Svensson CI, Tran TK, Fitzsimmons B, Yaksh TL, Hua XY. PMID: 17113581; PMCID: PMC2291024.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    196. The electrophysiology of de qi sensations. J Altern Complement Med. 2006 Oct; 12(8):743-50. Leung AY, Park J, Schulteis G, Duann JR, Yaksh T. PMID: 17034280.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    197. Opiate pharmacology of intrathecal granulomas. Anesthesiology. 2006 Sep; 105(3):590-8. Allen JW, Horais KA, Tozier NA, Yaksh TL. PMID: 16931994.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    198. Time course and role of morphine dose and concentration in intrathecal granuloma formation in dogs: a combined magnetic resonance imaging and histopathology investigation. Anesthesiology. 2006 Sep; 105(3):581-9. Allen JW, Horais KA, Tozier NA, Wegner K, Corbeil JA, Mattrey RF, Rossi SS, Yaksh TL. PMID: 16931993.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    199. Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study. Neuroscience. 2006 Sep 01; 141(3):1569-83. Kakinohana O, Hefferan MP, Nakamura S, Kakinohana M, Galik J, Tomori Z, Marsala J, Yaksh TL, Marsala M. PMID: 16797137.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    200. Covariance among age, spinal p38 MAP kinase activation and allodynia. J Pain. 2006 May; 7(5):337-45. Svensson CI, Schäfers M, Jones TL, Yaksh TL, Sorkin LS. PMID: 16632323.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    201. Characterization of interference with 6 commercial delta9-tetrahydrocannabinol immunoassays by efavirenz (glucuronide) in urine. Clin Chem. 2006 May; 52(5):896-7. Rossi S, Yaksh T, Bentley H, van den Brande G, Grant I, Ellis R. PMID: 16638958.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    202. Cancer-related bone pain is attenuated by a systemically available delta-opioid receptor agonist. Pain. 2006 May; 122(1-2):174-81. Brainin-Mattos J, Smith ND, Malkmus S, Rew Y, Goodman M, Taulane J, Yaksh TL. PMID: 16545911.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    203. Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs. Toxicol Sci. 2006 May; 91(1):286-98. Allen JW, Mantyh PW, Horais K, Tozier N, Rogers SD, Ghilardi JR, Cizkova D, Grafe MR, Richter P, Lappi DA, Yaksh TL. PMID: 16500924.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    204. Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour. Eur J Neurosci. 2006 Feb; 23(3):627-36. Shi TJ, Hua XY, Lu X, Malkmus S, Kinney J, Holmberg K, Wirz S, Ceccatelli S, Yaksh T, Bartfai T, Hökfelt T. PMID: 16487144.
      View in: PubMed   Mentions: 19  Translation:AnimalsCells
    205. Calcium channels as therapeutic targets in neuropathic pain. J Pain. 2006 Jan; 7(1 Suppl 1):S13-30. Yaksh TL. PMID: 16426997.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    206. Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia. Eur J Neurosci. 2005 Nov; 22(10):2431-40. Hua XY, Svensson CI, Matsui T, Fitzsimmons B, Yaksh TL, Webb M. PMID: 16307586.
      View in: PubMed   Mentions: 106  Translation:AnimalsCells
    207. Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. J Pharmacol Exp Ther. 2006 Jan; 316(1):466-75. Yaksh TL, Kokotos G, Svensson CI, Stephens D, Kokotos CG, Fitzsimmons B, Hadjipavlou-Litina D, Hua XY, Dennis EA. PMID: 16203828.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    208. Prostaglandin E2 release evoked by intrathecal dynorphin is dependent on spinal p38 mitogen activated protein kinase. Neuropeptides. 2005 Oct; 39(5):485-94. Svensson CI, Hua XY, Powell HC, Lai J, Porreca F, Yaksh TL. PMID: 16176831.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    209. Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain. Pain. 2005 Nov; 118(1-2):112-24. Nielsen CK, Lewis RJ, Alewood D, Drinkwater R, Palant E, Patterson M, Yaksh TL, McCumber D, Smith MT. PMID: 16154696.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    210. Unexpected pain in a dog: aberration or worthy of a citation? Agree to disagree. Lab Anim (NY). 2005 Sep; 34(8):19. Torchia M, Yaksh T. PMID: 16136070.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    211. The effect of Ting point (tendinomuscular meridians) electroacupuncture on thermal pain: a model for studying the neuronal mechanism of acupuncture analgesia. J Altern Complement Med. 2005 Aug; 11(4):653-61. Leung A, Khadivi B, Duann JR, Cho ZH, Yaksh T. PMID: 16131289.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    212. Qualitative and quantitative characterization of the thermal grill. Pain. 2005 Jul; 116(1-2):26-32. Leung AY, Wallace MS, Schulteis G, Yaksh TL. PMID: 15935558.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    213. Resting and evoked spinal substance P release during chronic intrathecal morphine infusion: parallels with tolerance and dependence. J Pharmacol Exp Ther. 2005 Sep; 314(3):1362-9. Gu G, Kondo I, Hua XY, Yaksh TL. PMID: 15908510.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    214. Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release. J Neurosci. 2005 Apr 06; 25(14):3651-60. Kondo I, Marvizon JC, Song B, Salgado F, Codeluppi S, Hua XY, Yaksh TL. PMID: 15814796; PMCID: PMC6725388.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    215. Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2. Br J Pharmacol. 2005 Apr; 144(7):940-52. Lucas KK, Svensson CI, Hua XY, Yaksh TL, Dennis EA. PMID: 15685208; PMCID: PMC1576074.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    216. Mechanisms of antinociception of spinal galanin: how does galanin inhibit spinal sensitization? Neuropeptides. 2005 Jun; 39(3):211-6. Hua XY, Salgado KF, Gu G, Fitzsimmons B, Kondo I, Bartfai T, Yaksh TL. PMID: 15944014.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    217. Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization. J Neurochem. 2005 Mar; 92(6):1508-20. Svensson CI, Fitzsimmons B, Azizi S, Powell HC, Hua XY, Yaksh TL. PMID: 15748168.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    218. Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice. Neuropeptides. 2005 Jun; 39(3):217-21. Malkmus S, Lu X, Bartfai T, Yaksh TL, Hua XY. PMID: 15944015.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    219. Spinal phospholipase A2 in inflammatory hyperalgesia: role of the small, secretory phospholipase A2. Neuroscience. 2005; 133(2):543-53. Svensson CI, Lucas KK, Hua XY, Powell HC, Dennis EA, Yaksh TL. PMID: 15885922.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    220. Spinal distribution and metabolism of 2'-O-(2-methoxyethyl)-modified oligonucleotides after intrathecal administration in rats. Neuroscience. 2005; 131(3):705-15. Butler M, Hayes CS, Chappell A, Murray SF, Yaksh TL, Hua XY. PMID: 15730875.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    221. Spinal implantation of hNT neurons and neuronal precursors: graft survival and functional effects in rats with ischemic spastic paraplegia. Eur J Neurosci. 2004 Nov; 20(9):2401-14. Marsala M, Kakinohana O, Yaksh TL, Tomori Z, Marsala S, Cizkova D. PMID: 15525281.
      View in: PubMed   Mentions: 20  Translation:HumansAnimalsCells
    222. Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord. J Neurocytol. 2004 Sep; 33(5):543-56. Khan IM, Wennerholm M, Singletary E, Polston K, Zhang L, Deerinck T, Yaksh TL, Taylor P. PMID: 15906161.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    223. A preclinical post laminectomy rat model mimics the human post laminectomy syndrome. J Neurosci Methods. 2004 Aug 30; 137(2):283-9. Massie JB, Huang B, Malkmus S, Yaksh TL, Kim CW, Garfin SR, Akeson WH. PMID: 15262072.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    224. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10470-5. Bartfai T, Lu X, Badie-Mahdavi H, Barr AM, Mazarati A, Hua XY, Yaksh T, Haberhauer G, Ceide SC, Trembleau L, Somogyi L, Kröck L, Rebek J. PMID: 15240875; PMCID: PMC478593.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    225. Intrathecal protease-activated receptor stimulation produces thermal hyperalgesia through spinal cyclooxygenase activity. J Pharmacol Exp Ther. 2004 Oct; 311(1):356-63. Koetzner L, Gregory JA, Yaksh TL. PMID: 15175421.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    226. Preclinical insights into the implementation of intrathecal midazolam: a cautionary tale. Anesth Analg. 2004 Jun; 98(6):1509-1511. Yaksh TL, Allen JW. PMID: 15155298.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    227. The use of intrathecal midazolam in humans: a case study of process. Anesth Analg. 2004 Jun; 98(6):1536-1545. Yaksh TL, Allen JW. PMID: 15155302.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    228. Intrathecal ketorolac in dogs and rats. Toxicol Sci. 2004 Aug; 80(2):322-34. Yaksh TL, Horais KA, Tozier N, Rathbun M, Richter P, Rossi S, Grafe M, Tong C, Meschter C, Cline JM, Eisenach J. PMID: 15141096.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    229. Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. J Neurosci. 2004 Mar 17; 24(11):2727-32. Ghilardi JR, Svensson CI, Rogers SD, Yaksh TL, Mantyh PW. PMID: 15028765; PMCID: PMC6729511.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    230. Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2. J Neurosci. 2004 Feb 11; 24(6):1451-8. Koetzner L, Hua XY, Lai J, Porreca F, Yaksh T. PMID: 14960618; PMCID: PMC6730335.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    231. Intrathecal but not intravenous opioids release adenosine from the spinal cord. J Pain. 2004 Feb; 5(1):64-8. Eisenach JC, Hood DD, Curry R, Sawynok J, Yaksh TL, Li X. PMID: 14975380.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    232. Tissue injury models of persistent nociception in rats. Methods Mol Med. 2004; 99:25-34. Allen JW, Yaksh TL. PMID: 15131326.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    233. Intrathecal catheterization and drug delivery in the rat. Methods Mol Med. 2004; 99:109-21. Malkmus SA, Yaksh TL. PMID: 15131333.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    234. Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat. Exp Neurol. 2004 Jan; 185(1):160-8. Schäfers M, Marziniak M, Sorkin LS, Yaksh TL, Sommer C. PMID: 14697327.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    235. Assessment of acute thermal nociception in laboratory animals. Methods Mol Med. 2004; 99:11-23. Allen JW, Yaksh TL. PMID: 15131325.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    236. Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways. J Comp Neurol. 2003 Dec 01; 467(1):44-59. Khan I, Osaka H, Stanislaus S, Calvo RM, Deerinck T, Yaksh TL, Taylor P. PMID: 14574679.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    237. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb; 308(2):574-82. Hua XY, Hayes CS, Hofer A, Fitzsimmons B, Kilk K, Langel U, Bartfai T, Yaksh TL. PMID: 14610237.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    238. Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. J Neurochem. 2003 Sep; 86(6):1534-44. Svensson CI, Marsala M, Westerlund A, Calcutt NA, Campana WM, Freshwater JD, Catalano R, Feng Y, Protter AA, Scott B, Yaksh TL. PMID: 12950462.
      View in: PubMed   Mentions: 151     Fields:    Translation:AnimalsCells
    239. Chronically infused intrathecal morphine in dogs. Anesthesiology. 2003 Jul; 99(1):174-87. Yaksh TL, Horais KA, Tozier NA, Allen JW, Rathbun M, Rossi SS, Sommer C, Meschter C, Richter PJ, Hildebrand KR. PMID: 12826858.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    240. Preclinical work leading to the development of spinal analgesia. Anesthesiology. 2003 Jul; 99(1):224-5. Yaksh TL. PMID: 12826864.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    241. A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance. J Neurosci Methods. 2003 Jun 30; 126(2):165-73. Hayes CS, Mulkmus SA, Cizkova D, Yaksh TL, Hua XY. PMID: 12814841.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    242. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. J Neurosci. 2003 Jun 15; 23(12):5031-40. South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, Woolf CJ, Heinemann SF, Inturrisi CE. PMID: 12832526; PMCID: PMC6741202.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    243. Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia. Neuroreport. 2003 Jun 11; 14(8):1153-7. Svensson CI, Hua XY, Protter AA, Powell HC, Yaksh TL. PMID: 12821799.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    244. Neuraxial morphine may trigger transient motor dysfunction after a noninjurious interval of spinal cord ischemia: a clinical and experimental study. Anesthesiology. 2003 Apr; 98(4):862-70. Kakinohana M, Marsala M, Carter C, Davison JK, Yaksh TL. PMID: 12657847.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    245. Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. J Neurosci. 2003 Apr 01; 23(7):3028-38. Schäfers M, Lee DH, Brors D, Yaksh TL, Sorkin LS. PMID: 12684490; PMCID: PMC6742101.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    246. Rapid quantification of the non-competitive NMDA antagonist MK-801 in canine cerebrospinal fluid and plasma by capillary gas chromatography-nitrogen phosphorus detection. J Pharm Biomed Anal. 2003 Feb 26; 31(2):243-50. Rossi S, Yaksh T. PMID: 12609663.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    247. Epidural ketamine in healthy children--what's the point? Anesth Analg. 2003 Feb; 96(2):626; author reply 626-7. Eisenach JC, Yaksh TL. PMID: 12538224.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    248. Effects of chronic intrathecal infusion of a partial differential opioid agonist in dogs. Toxicol Sci. 2003 Feb; 71(2):263-75. Horais K, Hruby V, Rossi S, Cizkova D, Meschter C, Dorr R, Yaksh TL. PMID: 12563112.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    249. Systemic and spinal analgesic activity of a delta-opioid-selective lanthionine enkephalin analog. J Pharmacol Exp Ther. 2003 Feb; 304(2):827-32. Svensson CI, Rew Y, Malkmus S, Schiller PW, Taulane JP, Goodman M, Yaksh TL. PMID: 12538839.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    250. Spinal amino acid release and repeated withdrawal in spinal morphine tolerant rats. Br J Pharmacol. 2003 Feb; 138(4):689-97. Ibuki T, Marsala M, Masuyama T, Yaksh TL. PMID: 12598423; PMCID: PMC1573708.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    251. Inflammatory masses associated with intrathecal drug infusion: a review of preclinical evidence and human data. Pain Med. 2002 Dec; 3(4):300-12. Yaksh TL, Hassenbusch S, Burchiel K, Hildebrand KR, Page LM, Coffey RJ. PMID: 15099235.
      View in: PubMed   Mentions: 21     Fields:    
    252. Safety in numbers: how do we study toxicity of spinal analgesics? Anesthesiology. 2002 Nov; 97(5):1047-9. Eisenach JC, Yaksh TL. PMID: 12411784.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    253. Nicotinic receptor gene cluster on rat chromosome 8 in nociceptive and blood pressure hyperresponsiveness. Physiol Genomics. 2002 Oct 29; 11(2):65-72. Khan IM, Singletary E, Alemayehu A, Stanislaus S, Printz MP, Yaksh TL, Taylor P. PMID: 12388796.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    254. Phase I safety assessment of intrathecal ketorolac. Pain. 2002 Oct; 99(3):599-604. Eisenach JC, Curry R, Hood DD, Yaksh TL. PMID: 12406536.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    255. Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs inflammatory pain. Pain. 2002 Oct; 99(3):397-406. Luger NM, Sabino MAC, Schwei MJ, Mach DB, Pomonis JD, Keyser CP, Rathbun M, Clohisy DR, Honore P, Yaksh TL, Mantyh PW. PMID: 12406514.
      View in: PubMed   Mentions: 61     Fields:    Translation:Animals
    256. Localization of N-type Ca2+ channels in the rat spinal cord following chronic constrictive nerve injury. Exp Brain Res. 2002 Dec; 147(4):456-63. Cizkova D, Marsala J, Lukacova N, Marsala M, Jergova S, Orendacova J, Yaksh TL. PMID: 12444477.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    257. Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands. J Med Chem. 2002 Aug 15; 45(17):3746-54. Rew Y, Malkmus S, Svensson C, Yaksh TL, Chung NN, Schiller PW, Cassel JA, DeHaven RN, Taulane JP, Goodman M. PMID: 12166947.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    258. Rapid quantification of the delta-opioid receptor selective enkephalin DPDPE in canine cerebrospinal fluid by liquid chromatography--mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 May 25; 772(1):73-9. Rossi S, Yaksh T. PMID: 12016017.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    259. Spinal and peripheral mu opioids and the development of secondary tactile allodynia after thermal injury. Anesth Analg. 2002 Apr; 94(4):968-74, table of contents. Nozaki-Taguchi N, Yaksh TL. PMID: 11916806.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    260. Pharmacology of spinal glutamatergic receptors in post-thermal injury-evoked tactile allodynia and thermal hyperalgesia. Anesthesiology. 2002 Mar; 96(3):617-26. Nozaki-Taguchi N, Yaksh TL. PMID: 11873037.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    261. Anterograde transport of tumor necrosis factor-alpha in the intact and injured rat sciatic nerve. J Neurosci. 2002 Jan 15; 22(2):536-45. Schäfers M, Geis C, Brors D, Yaksh TL, Sommer C. PMID: 11784800; PMCID: PMC6758659.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    262. Inhibition of spinal protein kinase Calpha expression by an antisense oligonucleotide attenuates morphine infusion-induced tolerance. Neuroscience. 2002; 113(1):99-107. Hua XY, Moore A, Malkmus S, Murray SF, Dean N, Yaksh TL, Butler M. PMID: 12123688.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    263. Future advances in pain pharmacology: what does the present say about the future? Proc West Pharmacol Soc. 2002; 45:211-8. Yaksh TL. PMID: 12434582.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    264. Effects of continuous lumbar intrathecal infusion of leptin in rats on weight regulation. Neuroscience. 2002; 110(4):703-10. Yaksh TL, Scott B, LeBel CL. PMID: 11934477.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    265. The spinal phospholipase-cyclooxygenase-prostanoid cascade in nociceptive processing. Annu Rev Pharmacol Toxicol. 2002; 42:553-83. Svensson CI, Yaksh TL. PMID: 11807183.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    266. Concentration-effect relationships for intravenous alfentanil and ketamine infusions in human volunteers: effects on acute thresholds and capsaicin-evoked hyperpathia. J Clin Pharmacol. 2002 Jan; 42(1):70-80. Wallace MS, Ridgeway B, Leung A, Schulteis G, Yaksh TL. PMID: 11808827.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    267. Spinal nicotinic receptor activity in a genetic model of hypertension. Clin Exp Hypertens. 2001 Oct; 23(7):555-68. Khan IM, Stanislaus S, Zhang L, Vaughn D, Printz MP, Yaksh TL, Taylor P. PMID: 11710757.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    268. Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonists. Anesthesiology. 2001 Oct; 95(4):965-73. Sorkin LS, Yaksh TL, Doom CM. PMID: 11605940.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    269. The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. J Neurosci. 2001 Aug 15; 21(16):5847-53. Yaksh TL, Dirig DM, Conway CM, Svensson C, Luo ZD, Isakson PC. PMID: 11487607; PMCID: PMC6763183.
      View in: PubMed   Mentions: 69     Fields:    Translation:Animals
    270. Vincristine-induced allodynia in the rat. Pain. 2001 Jul; 93(1):69-76. Nozaki-Taguchi N, Chaplan SR, Higuera ES, Ajakwe RC, Yaksh TL. PMID: 11406340.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    271. Sensory neurons are PARtial to pain. Nat Med. 2001 Jul; 7(7):772-3. Mantyh PW, Yaksh TL. PMID: 11433334.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    272. An automated flinch detecting system for use in the formalin nociceptive bioassay. J Appl Physiol (1985). 2001 Jun; 90(6):2386-402. Yaksh TL, Ozaki G, McCumber D, Rathbun M, Svensson C, Malkmus S, Yaksh MC. PMID: 11356806.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    273. A-85380 and epibatidine each interact with disparate spinal nicotinic receptor subtypes to achieve analgesia and nociception. J Pharmacol Exp Ther. 2001 Apr; 297(1):230-9. Khan IM, Stanislaus S, Zhang L, Taylor P, Yaksh TL. PMID: 11259549.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    274. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J Neurosci. 2001 Mar 15; 21(6):1868-75. Luo ZD, Chaplan SR, Higuera ES, Sorkin LS, Stauderman KA, Williams ME, Yaksh TL. PMID: 11245671; PMCID: PMC6762626.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    275. Concentration-effect relationship of intravenous alfentanil and ketamine on peripheral neurosensory thresholds, allodynia and hyperalgesia of neuropathic pain. Pain. 2001 Mar; 91(1-2):177-87. Leung A, Wallace MS, Ridgeway B, Yaksh T. PMID: 11240090.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    276. Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia. Brain Res. 2000 Sep 22; 877(2):314-21. Wajima Z, Hua XY, Yaksh TL. PMID: 10986346.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    277. Intrathecal nalbuphine after cesarean delivery: are we ready? Anesth Analg. 2000 Sep; 91(3):505-8. Yaksh T, Birnbach DJ. PMID: 10960366.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    278. Evidence-based review of the literature on intrathecal delivery of pain medication. J Pain Symptom Manage. 2000 Aug; 20(2):S12-36. Bennett G, Serafini M, Burchiel K, Buchser E, Classen A, Deer T, Du Pen S, Ferrante FM, Hassenbusch SJ, Lou L, Maeyaert J, Penn R, Portenoy RK, Rauck R, Willis KD, Yaksh T. PMID: 10989255.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    279. Clinical guidelines for intraspinal infusion: report of an expert panel. PolyAnalgesic Consensus Conference 2000. J Pain Symptom Manage. 2000 Aug; 20(2):S37-43. Bennett G, Burchiel K, Buchser E, Classen A, Deer T, Du Pen S, Ferrante FM, Hassenbusch SJ, Lou L, Maeyaert J, Penn R, Portenoy RK, Rauck R, Serafini M, Willis KD, Yaksh T. PMID: 10989256.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    280. Future directions in the management of pain by intraspinal drug delivery. J Pain Symptom Manage. 2000 Aug; 20(2):S44-50. Bennett G, Deer T, Du Pen S, Rauck R, Yaksh T, Hassenbusch SJ. PMID: 10989257.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    281. The effects of intrathecal morphine encapsulated in L- and D-dipalmitoylphosphatidyl choline liposomes on acute nociception in rats. Anesth Analg. 2000 Aug; 91(2):423-8. Nishiyama T, Ho RJ, Shen DD, Yaksh TL. PMID: 10910861.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    282. Transient spinal cord ischemia in rat: the time course of spinal FOS protein expression and the effect of intraischemic hypothermia (27 degrees C). Cell Mol Neurobiol. 2000 Jun; 20(3):351-65. Yang LC, Orendacova J, Wang V, Ishikawa T, Yaksh TL, Marsala M. PMID: 10789833.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    283. Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion. Pain. 2000 Apr; 85(3):395-404. Granados-Soto V, Kalcheva I, Hua XY, Newton A, Yaksh TL. PMID: 10781912.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    284. Long-term spinal analgesic delivery: a review of the preclinical and clinical literature. Reg Anesth Pain Med. 2000 Mar-Apr; 25(2):117-57. Wallace M, Yaksh TL. PMID: 10746527.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    285. Characterization of spinal amino acid release and touch-evoked allodynia produced by spinal glycine or GABA(A) receptor antagonist. Neuroscience. 2000; 95(3):781-6. Ishikawa T, Marsala M, Sakabe T, Yaksh TL. PMID: 10670445.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    286. Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. Anesthesiology. 2000 Jan; 92(1):75-83. Wallace MS, Ridgeway BM, Leung AY, Gerayli A, Yaksh TL. PMID: 10638902.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    287. Safety assessment of encapsulated morphine delivered epidurally in a sustained-release multivesicular liposome preparation in dogs. Drug Deliv. 2000 Jan-Mar; 7(1):27-36. Yaksh TL, Provencher JC, Rathbun ML, Myers RR, Powell H, Richter P, Kohn FR. PMID: 10895417.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    288. Inhibition of spinal protein kinase C reduces nerve injury-induced tactile allodynia in neuropathic rats. Neurosci Lett. 1999 Dec 03; 276(2):99-102. Hua XY, Chen P, Yaksh TL. PMID: 10624801.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    289. Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonist. Neuroreport. 1999 Nov 26; 10(17):3523-6. Sorkin LS, Yaksh TL, Doom CM. PMID: 10619637.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    290. A drug has to do what a drug has to do. Anesth Analg. 1999 Nov; 89(5):1075-7. Yaksh TL. PMID: 10553814.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    291. Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development. J Neurosci. 1999 Nov 01; 19(21):9201-8. Luo ZD, Chaplan SR, Scott BP, Cizkova D, Calcutt NA, Yaksh TL. PMID: 10531423; PMCID: PMC6782898.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    292. Generation and analysis of GluR5(Q636R) kainate receptor mutant mice. J Neurosci. 1999 Oct 15; 19(20):8757-64. Sailer A, Swanson GT, Pérez-Otaño I, O'Leary L, Malkmus SA, Dyck RH, Dickinson-Anson H, Schiffer HH, Maron C, Yaksh TL, Gage FH, O'Gorman S, Heinemann SF. PMID: 10516295; PMCID: PMC6782774.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    293. Evaluation of interaction between gabapentin and ibuprofen on the formalin test in rats. Anesthesiology. 1999 Oct; 91(4):1006-13. Yoon MH, Yaksh TL. PMID: 10519504.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    294. Preclinical toxicity screening of intrathecal adenosine in rats and dogs. Anesthesiology. 1999 Sep; 91(3):824-32. Chiari A, Yaksh TL, Myers RR, Provencher J, Moore L, Lee CS, Eisenach JC. PMID: 10485794.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    295. Spinal systems and pain processing: development of novel analgesic drugs with mechanistically defined models. Trends Pharmacol Sci. 1999 Aug; 20(8):329-37. Yaksh TL. PMID: 10431212.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    296. The effect of intrathecal gabapentin on pain behavior and hemodynamics on the formalin test in the rat. Anesth Analg. 1999 Aug; 89(2):434-9. Yoon MH, Yaksh TL. PMID: 10439761.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    297. Regulation of spinal nociceptive processing: where we went when we wandered onto the path marked by the gate. Pain. 1999 Aug; Suppl 6:S149-S152. Yaksh TL. PMID: 10491984.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    298. The spinal biology in humans and animals of pain states generated by persistent small afferent input. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7680-6. Yaksh TL, Hua XY, Kalcheva I, Nozaki-Taguchi N, Marsala M. PMID: 10393880; PMCID: PMC33601.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    299. Pharmacokinetics and efficacy of epidurally delivered sustained-release encapsulated morphine in dogs. Anesthesiology. 1999 May; 90(5):1402-12. Yaksh TL, Provencher JC, Rathbun ML, Kohn FR. PMID: 10319789.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    300. Loperamide (ADL 2-1294), an opioid antihyperalgesic agent with peripheral selectivity. J Pharmacol Exp Ther. 1999 Apr; 289(1):494-502. DeHaven-Hudkins DL, Burgos LC, Cassel JA, Daubert JD, DeHaven RN, Mansson E, Nagasaka H, Yu G, Yaksh T. PMID: 10087042.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    301. Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids. Neuroscience. 1999 Mar; 89(2):525-34. Hua XY, Chen P, Marsala M, Yaksh TL. PMID: 10077333.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    302. In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. Br J Pharmacol. 1999 Mar; 126(6):1333-40. Dirig DM, Yaksh TL. PMID: 10217526; PMCID: PMC1565904.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    303. Characterization of the antihyperalgesic action of a novel peripheral mu-opioid receptor agonist--loperamide. Anesthesiology. 1999 Jan; 90(1):225-34. Nozaki-Taguchi N, Yaksh TL. PMID: 9915332.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    304. Spinal synthesis and release of prostanoids after peripheral injury and inflammation. Adv Exp Med Biol. 1999; 469:401-8. Dirig DM, Yaksh TL. PMID: 10667359.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    305. Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists. Neuropharmacology. 1998 Dec; 37(12):1515-25. Khan IM, Buerkle H, Taylor P, Yaksh TL. PMID: 9886674.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    306. New epidural drugs: primum non nocere. Anesth Analg. 1998 Nov; 87(5):1211-2. Eisenach JC, James FM, Gordh T, Yaksh TL. PMID: 9806714.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    307. A novel model of primary and secondary hyperalgesia after mild thermal injury in the rat. Neurosci Lett. 1998 Sep 18; 254(1):25-8. Nozaki-Taguchi N, Yaksh TL. PMID: 9780083.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    308. Effects of intrathecal NMDA and non-NMDA antagonists on acute thermal nociception and their interaction with morphine. Anesthesiology. 1998 Sep; 89(3):715-22. Nishiyama T, Yaksh TL, Weber E. PMID: 9743410.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    309. Pharmacological evidence for different alpha 2-adrenergic receptor sites mediating analgesia and sedation in the rat. Br J Anaesth. 1998 Aug; 81(2):208-15. Buerkle H, Yaksh TL. PMID: 9813525.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    310. Synthesis and biological activity of a novel methylamine-bridged enkephalin analogue (MABE): a new route to cyclic peptides and peptidomimetics. J Med Chem. 1998 Jul 02; 41(14):2631-5. Shreder K, Zhang L, Dang T, Yaksh TL, Umeno H, DeHaven R, Daubert J, Goodman M. PMID: 9651168.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    311. Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats. J Pharmacol Exp Ther. 1998 Jun; 285(3):1031-8. Dirig DM, Isakson PC, Yaksh TL. PMID: 9618405.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    312. Neurodegeneration induced by reversed microdialysis of NMDA; a quantitative model for excitotoxicity in vivo. Brain Res. 1998 Apr 13; 789(2):347-50. Vanický I, Marsala M, Yaksh TL. PMID: 9573401.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    313. Effects of endotracheal intubation on airway neuropeptide content, arterial oxygenation and lung volumes in anaesthetized rats. Eur J Clin Invest. 1998 Mar; 28(3):249-55. Högman M, Reber A, Hua XY, Dueck R, Yaksh TL. PMID: 9568472.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    314. Effect of continuous spinal remifentanil infusion on behaviour and spinal glutamate release evoked by subcutaneous formalin in the rat. Br J Anaesth. 1998 Mar; 80(3):348-53. Buerkle H, Marsala M, Yaksh TL. PMID: 9623437.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    315. Spinal neurokinin NK1 receptor down-regulation and antinociception: effects of spinal NK1 receptor antisense oligonucleotides and NK1 receptor occupancy. J Neurochem. 1998 Feb; 70(2):688-98. Hua XY, Chen P, Polgar E, Nagy I, Marsala M, Phillips E, Wollaston L, Urban L, Yaksh TL, Webb M. PMID: 9453563.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    316. The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat. Anesth Analg. 1998 Feb; 86(2):348-54. Jun JH, Yaksh TL. PMID: 9459247.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    317. Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia. Anesthesiology. 1998 Jan; 88(1):196-205. Partridge BJ, Chaplan SR, Sakamoto E, Yaksh TL. PMID: 9447873.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    318. Mechanism of action of nonsteroidal anti-inflammatory drugs. Cancer Invest. 1998; 16(7):509-27. Yaksh TL, Dirig DM, Malmberg AB. PMID: 9774958.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    319. [Pharmacology of spinal facilitation: the basis for preventive analgesia]. Rev Esp Anestesiol Reanim. 1998 Jan; 45(1):17-23. Yáñez AM, Peleteiro-Ramos R, Camba MA, Yaksh TL. PMID: 9580459.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    320. Fate of the predominant phospholipid component of DepoFoam drug delivery matrix after intrathecal administration of sustained-release encapsulated cytarabine in rats. Drug Deliv. 1998; 5(2):143-51. Kohn FR, Malkmus SA, Brownson EA, Rossi SS, Yaksh TL. PMID: 19570006.
      View in: PubMed   Mentions: 9     Fields:    
    321. Adrenomedullary secretion of DOPA, catecholamines, catechol metabolites, and neuropeptides. J Neurochem. 1997 Dec; 69(6):2413-20. Chritton SL, Chinnow SL, Grabau C, Dousa MK, Lucas D, Roddy D, Yaksh TL, Tyce GM. PMID: 9375673.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    322. Characterization of variables defining hindpaw withdrawal latency evoked by radiant thermal stimuli. J Neurosci Methods. 1997 Oct 03; 76(2):183-91. Dirig DM, Salami A, Rathbun ML, Ozaki GT, Yaksh TL. PMID: 9350970.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimals
    323. Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma--a report of a series. Anesth Analg. 1997 Oct; 85(4):794-6. Wallace MS, Lee J, Sorkin L, Dunn JS, Yaksh T, Yu A. PMID: 9322457.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    324. Characterization of muscarinic receptor subtypes that mediate antinociception in the rat spinal cord. Anesth Analg. 1997 Oct; 85(4):847-53. Naguib M, Yaksh TL. PMID: 9322468.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    325. Effect of spinal cyclooxygenase inhibitors in rat using the formalin test and in vitro prostaglandin E2 release. Eur J Pharmacol. 1997 Jul 23; 331(2-3):155-60. Dirig DM, Konin GP, Isakson PC, Yaksh TL. PMID: 9274974.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    326. Antinociception induced by civamide, an orally active capsaicin analogue. Pain. 1997 Jul; 71(3):313-22. Hua XY, Chen P, Hwang J, Yaksh TL. PMID: 9231875.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    327. Kinetic and safety studies on intrathecally infused recombinant-methionyl human brain-derived neurotrophic factor in dogs. Fundam Appl Toxicol. 1997 Jul; 38(1):89-100. Yaksh TL, Rathbun ML, Dragani JC, Malkmus S, Bourdeau AR, Richter P, Powell H, Myers RR, Lebel CP. PMID: 9268608.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    328. Technique of selective spinal cord cooling in rat: methodology and application. J Neurosci Methods. 1997 Jun 06; 74(1):97-106. Marsala M, Galik J, Ishikawa T, Yaksh TL. PMID: 9210579.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    329. Temperature dependency of basal and evoked release of amino acids and calcitonin gene-related peptide from rat dorsal spinal cord. J Neurosci. 1997 Jun 01; 17(11):4406-14. Dirig DM, Hua XY, Yaksh TL. PMID: 9151757; PMCID: PMC6573525.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    330. Spinal infusion of N-methyl-D-aspartate antagonist MK801 induces hypersensitivity to the spinal alpha-2 agonist ST91 in the rat. J Pharmacol Exp Ther. 1997 Jun; 281(3):1219-25. Dunbar SA, Yaksh TL. PMID: 9190856.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    331. Concentration-effect relations for intravenous lidocaine infusions in human volunteers: effects on acute sensory thresholds and capsaicin-evoked hyperpathia. Anesthesiology. 1997 Jun; 86(6):1262-72. Wallace MS, Laitin S, Licht D, Yaksh TL. PMID: 9197294.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    332. Effect of subarachnoid gabapentin on tactile-evoked allodynia in a surgically induced neuropathic pain model in the rat. Reg Anesth. 1997 May-Jun; 22(3):249-56. Hwang JH, Yaksh TL. PMID: 9168217.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    333. Epibatidine binding sites and activity in the spinal cord. Brain Res. 1997 Apr 11; 753(2):269-82. Khan IM, Yaksh TL, Taylor P. PMID: 9125412.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    334. Knee joint inflammation attenuates spinal FOS expression after unilateral paw formalin injection in rat. Neurosci Lett. 1997 Apr 04; 225(2):89-92. Yang LC, Marsala M, Orendacova J, Yaksh TL. PMID: 9147381.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    335. Effect of transient naloxone antagonism on tolerance development in rats receiving continuous spinal morphine infusion. Pain. 1997 Apr; 70(2-3):125-32. Ibuki T, Dunbar SA, Yaksh TL. PMID: 9150285.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    336. An improved method for the measurement of lidocaine and its metabolites in rat plasma. Ther Drug Monit. 1997 Apr; 19(2):179-84. Rossi SS, Moore AC, Hagey LR, Yaksh TL, Chaplan SR. PMID: 9108647.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    337. Capsaicin-evoked release of pituitary adenylate cyclase activating peptide (PACAP) and calcitonin gene-related peptide (CGRP) from rat spinal cord in vivo. Regul Pept. 1997 Mar 26; 69(2):83-7. Zhang Y, Malmberg AB, Yaksh TL, Sjölund B, Sundler F, Håkanson R. PMID: 9178350.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    338. The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat. Pain. 1997 Mar; 70(1):15-22. Hwang JH, Yaksh TL. PMID: 9106805.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    339. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther. 1997 Feb; 280(2):829-38. Chaplan SR, Malmberg AB, Yaksh TL. PMID: 9023297.
      View in: PubMed   Mentions: 81     Fields:    Translation:Animals
    340. Pain after injury: some basic mechanisms. J Fla Med Assoc. 1997 Jan; 84(1):16-9. Yaksh TL. PMID: 9037993.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    341. An animal model of pain produced by systemic administration of an immunotherapeutic anti-ganglioside antibody. Pain. 1997 Jan; 69(1-2):119-25. Slart R, Yu AL, Yaksh TL, Sorkin LS. PMID: 9060021.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    342. Pharmacology and mechanisms of opioid analgesic activity. Acta Anaesthesiol Scand. 1997 Jan; 41(1 Pt 2):94-111. Yaksh TL. PMID: 9061092.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimals
    343. Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram. Anesth Analg. 1997 Jan; 84(1):133-8. Dowlatshahi P, Yaksh TL. PMID: 8989014.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    344. Hyperalgesia-associated spinal synthesis and release of prostaglandins. Adv Exp Med Biol. 1997; 433:205-8. Dirig DM, Yaksh TL. PMID: 9561136.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    345. The pharmacokinetics of lignocaine in humans during a computer-controlled infusion. Eur J Pain. 1997; 1(2):141-8. Dyck JB, Wallace MS, Lu JQ, Rossi SS, Yaksh TL. PMID: 15102415.
      View in: PubMed   Mentions: 3     Fields:    
    346. Thermal hyperalgesia in rat evoked by intrathecal substance P at multiple stimulus intensities reflects an increase in the gain of nociceptive processing. Neurosci Lett. 1996 Dec 13; 220(2):93-6. Dirig DM, Yaksh TL. PMID: 8981481.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    347. Spinal nicotinic receptor expression in spontaneously hypertensive rats. Hypertension. 1996 Dec; 28(6):1093-9. Khan IM, Youngblood KL, Printz MP, Yaksh TL, Taylor P. PMID: 8952602.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    348. Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. Pain. 1996 Dec; 68(2-3):293-9. Calcutt NA, Jorge MC, Yaksh TL, Chaplan SR. PMID: 9121817.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    349. Effect of spinal kainic acid receptor activation on spinal amino acid and prostaglandin E2 release in rat. Neuroscience. 1996 Nov; 75(2):453-61. Yang LC, Marsala M, Yaksh TL. PMID: 8931009.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    350. Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: a chronic microdialysis study. Pain. 1996 Oct; 67(2-3):345-54. Yang LC, Marsala M, Yaksh TL. PMID: 8951928.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    351. Peripheral and spinal actions of opioids in the blockade of the autonomic response evoked by compression of the inflamed knee joint. Anesthesiology. 1996 Oct; 85(4):808-16. Nagasaka H, Awad H, Yaksh TL. PMID: 8873551.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    352. Effects of spinal naloxone and naltrindole on the antinociceptive action of intrathecally administered dexmedetomidine. J Anesth. 1996 Sep; 10(3):194-8. Takano Y, Takano M, Sato I, Yaksh TL. PMID: 23839625.
      View in: PubMed   Mentions: 1     Fields:    
    353. Equianalgesic doses of subcutaneous but not intrathecal morphine alter phenotypic expression of cell surface markers and mitogen-induced proliferation in rat lymphocytes. Anesthesiology. 1996 Aug; 85(2):355-65. Hamra JG, Yaksh TL. PMID: 8712452.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    354. Intrathecal nicotinic agonist-elicited release of excitatory amino acids as measured by in vivo spinal microdialysis in rats. J Pharmacol Exp Ther. 1996 Jul; 278(1):97-106. Khan IM, Marsala M, Printz MP, Taylor P, Yaksh TL. PMID: 8764340.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    355. Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury. Pain. 1996 Jul; 66(1):69-77. Wallace MS, Dyck BJ, Rossi SS, Yaksh TL. PMID: 8857633.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    356. Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists. J Pharmacol Exp Ther. 1996 Jun; 277(3):1642-8. Lee YW, Yaksh TL. PMID: 8667233.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    357. Halothane inhibits T cell proliferation and interleukin-2 receptor expression in rats. Immunopharmacol Immunotoxicol. 1996 May; 18(2):323-36. Hamra JG, Yaksh TL. PMID: 8771374.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    358. Concurrent spinal infusion of MK801 blocks spinal tolerance and dependence induced by chronic intrathecal morphine in the rat. Anesthesiology. 1996 May; 84(5):1177-88. Dunbar S, Yaksh TL. PMID: 8624012.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    359. Spinal amino acid release and precipitated withdrawal in rats chronically infused with spinal morphine. J Neurosci. 1996 Apr 15; 16(8):2758-66. Jhamandas KH, Marsala M, Ibuki T, Yaksh TL. PMID: 8786451; PMCID: PMC6578766.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    360. The effect of pituitary adenylate cyclase activating peptide (PACAP) on the nociceptive formalin test. Neurosci Lett. 1996 Apr 05; 207(3):187-90. Zhang Y, Malmberg AB, Sjölund B, Yaksh TL. PMID: 8728481.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    361. [Concurrent characterization of spinal amino acid release and touch-evoked allodynia produced by spinal glycine or GABAA receptor antagonists]. Masui. 1996 Apr; 45(4):439-44. Ishikawa T, Yaksh TL. PMID: 8725598.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    362. Continuous intrathecal administration of shortlasting mu opioids remifentanil and alfentanil in the rat. Anesthesiology. 1996 Apr; 84(4):926-35. Buerkle H, Yaksh TL. PMID: 8638848.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    363. Effect of spinal infusion of L-NAME, a nitric oxide synthase inhibitor, on spinal tolerance and dependence induced by chronic intrathecal morphine in the rat. Neurosci Lett. 1996 Mar 22; 207(1):33-6. Dunbar S, Yaksh TL. PMID: 8710203.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    364. Changes in spontaneous unit activity in lumbar spinal cord after reversible aortic occlusion in the rat. Neurosci Lett. 1996 Mar 22; 207(1):45-8. Galik J, Marsala M, Yaksh TL. PMID: 8710206.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    365. Simultaneous extraction of sufentanil and midazolam from human plasma. Clin Chim Acta. 1996 Jan 15; 244(1):103-10. Rossi SS, Dyck JB, Yaksh TL. PMID: 8919205.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    366. Horizons in Pain Research. San Diego, California, May 19-21, 1995. Anesthesiology. 1996 Jan; 84(1):245-8. Yaksh TL. PMID: 8572351.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    367. Comparison of the spinal actions of the mu-opioid remifentanil with alfentanil and morphine in the rat. Anesthesiology. 1996 Jan; 84(1):94-102. Buerkle H, Yaksh TL. PMID: 8572360.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    368. Release of beta-endorphin immunoreactivity into ventriculo-cisternal perfusate by lumbar intrathecal capsaicin in the rat. Brain Res. 1995 Dec 01; 701(1-2):192-200. Bach FW, Yaksh TL. PMID: 8925284.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    369. The spinal loop dialysis catheter: characterization of use in the unanesthetized rat. J Neurosci Methods. 1995 Nov; 62(1-2):43-53. Marsala M, Malmberg AB, Yaksh TL. PMID: 8750084.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    370. Antinociception and side effects of L- and D-dipalmitoylphosphatidyl choline liposome-encapsulated alfentanil after spinal delivery in rats. Pharmacol Toxicol. 1995 Nov; 77(5):333-40. Isackson J, Wallace MS, Ho RJ, Shen DD, Yaksh TL. PMID: 8778746.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    371. Systemic and supraspinal, but not spinal, opiates suppress allodynia in a rat neuropathic pain model. Neurosci Lett. 1995 Oct 20; 199(2):111-4. Lee YW, Chaplan SR, Yaksh TL. PMID: 8584236.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    372. Different effects of two aldose reductase inhibitors on nociception and prostaglandin E. Eur J Pharmacol. 1995 Oct 16; 285(2):189-97. Calcutt NA, Li L, Yaksh TL, Malmberg AB. PMID: 8566138.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    373. Intrathecal baclofen and muscimol, but not midazolam, are antinociceptive using the rat-formalin model. J Pharmacol Exp Ther. 1995 Oct; 275(1):219-27. Dirig DM, Yaksh TL. PMID: 7562553.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    374. Characterization of the spinal antinociceptive activity of constrained peptidomimetic opioids. J Pharmacol Exp Ther. 1995 Oct; 275(1):63-72. Yaksh TL, Malmberg AB, Ro S, Schiller P, Goodman M. PMID: 7562596.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    375. Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats. Anesthesiology. 1995 Oct; 83(4):775-85. Chaplan SR, Bach FW, Shafer SL, Yaksh TL. PMID: 7574057.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    376. Cerebrospinal fluid beta-endorphin in models of hyperalgesia in the rat. Regul Pept. 1995 Sep 22; 59(1):79-86. Bach FW, Chaplan SR, Jang J, Yaksh TL. PMID: 12506417.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    377. Release into ventriculo-cisternal perfusate of beta-endorphin- and Met-enkephalin-immunoreactivity: effects of electrical stimulation in the arcuate nucleus and periaqueductal gray of the rat. Brain Res. 1995 Sep 04; 690(2):167-76. Bach FW, Yaksh TL. PMID: 8535833.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    378. Differential right shifts in the dose-response curve for intrathecal morphine and sufentanil as a function of stimulus intensity. Pain. 1995 Sep; 62(3):321-328. Dirig DM, Yaksh TL. PMID: 8657432.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    379. Pharmacology of calcitonin gene related peptide release from sensory terminals in the rat trachea. Can J Physiol Pharmacol. 1995 Jul; 73(7):999-1006. Hua XY, Wong S, Jinno S, Yaksh TL. PMID: 8846444.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    380. Highly potent side chain-main chain cyclized dermorphin-deltorphin analogues: an integrated approach including synthesis, bioassays, NMR spectroscopy and molecular modelling. J Pept Sci. 1995 May-Jun; 1(3):157-74. Ro S, Zhu Q, Lee CW, Goodman M, Darlak K, Spatola AF, Chung NN, Schiller PW, Malmberg AB, Yaksh TL, et al. PMID: 9222993.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    381. Touch-evoked agitation produced by spinally administered phospholipid emulsion and liposomes in rats. Structure-activity relation. Anesthesiology. 1995 May; 82(5):1189-98. Yanez AM, Wallace M, Ho R, Shen D, Yaksh TL. PMID: 7741294.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    382. Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats. J Neurosci. 1995 Apr; 15(4):2768-76. Malmberg AB, Yaksh TL. PMID: 7722627; PMCID: PMC6577797.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    383. Release of beta-endorphin immunoreactivity from brain by activation of a hypothalamic N-methyl-D-aspartate receptor. Neuroscience. 1995 Apr; 65(3):775-83. Bach FW, Yaksh TL. PMID: 7609876.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    384. Effects of intrathecal mu, delta, and kappa agonists on thermally evoked cardiovascular and nociceptive reflexes in halothane-anesthetized rats. Anesth Analg. 1995 Mar; 80(3):437-43. Nagasaka H, Yaksh TL. PMID: 7864404.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    385. The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats. Br J Pharmacol. 1995 Mar; 114(5):1069-75. Malmberg AB, Yaksh TL. PMID: 7780642; PMCID: PMC1510315.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    386. Analysis of drug interaction between intrathecal clonidine and MK-801 in peripheral neuropathic pain rat model. Anesthesiology. 1995 Mar; 82(3):741-8. Lee YW, Yaksh TL. PMID: 7879942.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    387. Studies on the safety of chronically administered intrathecal neostigmine methylsulfate in rats and dogs. Anesthesiology. 1995 Feb; 82(2):412-27. Yaksh TL, Grafe MR, Malkmus S, Rathbun ML, Eisenach JC. PMID: 7856900.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    388. Retrovirus-mediated expression of an artificial beta-endorphin precursor in primary fibroblasts. J Neurochem. 1995 Feb; 64(2):475-81. Beutler AS, Banck MS, Bach FW, Gage FH, Porreca F, Bilsky EJ, Yaksh TL. PMID: 7830038.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    389. Cardiorespiratory and spinal cord blood flow effects of intrathecal neostigmine methylsulfate, clonidine, and their combination in sheep. Anesthesiology. 1995 Feb; 82(2):428-35. Hood DD, Eisenach JC, Tong C, Tommasi E, Yaksh TL. PMID: 7856901.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    390. Reversal of nerve ligation-induced allodynia by spinal alpha-2 adrenoceptor agonists. J Pharmacol Exp Ther. 1995 Jan; 272(1):207-14. Yaksh TL, Pogrel JW, Lee YW, Chaplan SR. PMID: 7815335.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    391. Effect of continuous intrathecal infusion of omega-conopeptides, N-type calcium-channel blockers, on behavior and antinociception in the formalin and hot-plate tests in rats. Pain. 1995 Jan; 60(1):83-90. Malmberg AB, Yaksh TL. PMID: 7715945.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    392. Future directions in the pharmacological management of hyperalgesic and allodynic pain states: the NMDA receptor. NIDA Res Monogr. 1995; 147:84-103. Yaksh TL, Chaplan SR, Malmberg AB. PMID: 8742782.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    393. Capsaicin-evoked prostaglandin E2 release in spinal cord slices: relative effect of cyclooxygenase inhibitors. Eur J Pharmacol. 1994 Dec 27; 271(2-3):293-9. Malmberg AB, Yaksh TL. PMID: 7705429.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    394. Stimulatory pathways and sites of action of intrathecally administered nicotinic agents. J Pharmacol Exp Ther. 1994 Dec; 271(3):1550-7. Khan IM, Taylor P, Yaksh TL. PMID: 7996469.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    395. Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension. Hypertension. 1994 Nov; 24(5):611-9. Khan IM, Printz MP, Yaksh TL, Taylor P. PMID: 7960022.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    396. Long-term perfusion of the cerebroventricular system of dogs without leakage to the peripheral circulation. Am J Physiol. 1994 Nov; 267(5 Pt 2):R1309-19. Nitecki S, Karmeli R, Harty GJ, Kamei C, Yaksh TL, Szurszewski JH. PMID: 7977859.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    397. Analgesic and neurotoxic effects of intrathecal corticosteroids in rats. Anesthesiology. 1994 Nov; 81(5):1198-205. Abram SE, Marsala M, Yaksh TL. PMID: 7978478.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    398. Characterization of muscarinic receptors involved in tracheal CGRP release. Neuroreport. 1994 Oct 27; 5(16):2133-6. Hua XY, Back SM, Yaksh TL. PMID: 7865762.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    399. Pharmacology and toxicology of chronically infused epidural clonidine.HCl in dogs. Fundam Appl Toxicol. 1994 Oct; 23(3):319-35. Yaksh TL, Rathbun M, Jage J, Mirzai T, Grafe M, Hiles RA. PMID: 7835532.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    400. Antinociception and side effects of liposome-encapsulated alfentanil after spinal delivery in rats. Anesth Analg. 1994 Oct; 79(4):778-86. Wallace MS, Yanez AM, Ho RJ, Shen DD, Yaksh TL. PMID: 7943792.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    401. Multiple mechanisms for the effects of capsaicin, bradykinin and nicotine on CGRP release from tracheal afferent nerves: role of prostaglandins, sympathetic nerves and mast cells. Neuropharmacology. 1994 Oct; 33(10):1147-54. Hua XY, Jinno S, Back SM, Tam EK, Yaksh TL. PMID: 7862250.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    402. Spinal delivery of sufentanil, alfentanil, and morphine in dogs. Physiologic and toxicologic investigations. Anesthesiology. 1994 Oct; 81(4):899-920. Sabbe MB, Grafe MR, Mjanger E, Tiseo PJ, Hill HF, Yaksh TL. PMID: 7943841.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    403. Effect of graded hypothermia (27 degrees to 34 degrees C) on behavioral function, histopathology, and spinal blood flow after spinal ischemia in rat. Stroke. 1994 Oct; 25(10):2038-46. Marsala M, Vanicky I, Yaksh TL. PMID: 8091450.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    404. Spinal somatostatin for patients with cancer. Risk-benefit assessment of an analgesic. Anesthesiology. 1994 Sep; 81(3):531-3. Yaksh TL. PMID: 7916545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    405. Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats. Pain. 1994 Sep; 58(3):413-420. Calcutt NA, Malmberg AB, Yamamoto T, Yaksh TL. PMID: 7838591.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    406. Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N- and P-type channels inhibits formalin-induced nociception. J Neurosci. 1994 Aug; 14(8):4882-90. Malmberg AB, Yaksh TL. PMID: 8046458; PMCID: PMC6577170.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    407. Differential temperature sensitivity of ischemia-induced glutamate release and eicosanoid production in rats. Brain Res. 1994 Jul 11; 650(2):205-11. Patel PM, Drummond JC, Cole DJ, Yaksh TL. PMID: 7953685.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    408. Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine. J Pharmacol Exp Ther. 1994 Jul; 270(1):159-66. Khan IM, Yaksh TL, Taylor P. PMID: 8035312.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    409. Cardiovascular and behavioral responses to nicotinic agents administered intrathecally. J Pharmacol Exp Ther. 1994 Jul; 270(1):150-8. Khan IM, Taylor P, Yaksh TL. PMID: 8035311.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    410. Transient spinal ischemia in rat: characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damage. J Cereb Blood Flow Metab. 1994 Jul; 14(4):604-14. Marsala M, Sorkin LS, Yaksh TL. PMID: 8014207.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    411. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods. 1994 Jul; 53(1):55-63. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. PMID: 7990513.
      View in: PubMed   Mentions: 3217     Fields:    Translation:Animals
    412. Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems. Anesthesiology. 1994 Jun; 80(6):1338-48. Naguib M, Yaksh TL. PMID: 8010479.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    413. Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia. J Pharmacol Exp Ther. 1994 Jun; 269(3):1117-23. Chaplan SR, Pogrel JW, Yaksh TL. PMID: 8014856.
      View in: PubMed   Mentions: 89     Fields:    Translation:Animals
    414. Antinociceptive effect of spinally delivered prostaglandin E receptor antagonists in the formalin test on the rat. Neurosci Lett. 1994 May 23; 173(1-2):193-6. Malmberg AB, Rafferty MF, Yaksh TL. PMID: 7936413.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    415. Spinal and systemic action of the alpha 2 receptor agonist dexmedetomidine in dogs. Antinociception and carbon dioxide response. Anesthesiology. 1994 May; 80(5):1057-72. Sabbe MB, Penning JP, Ozaki GT, Yaksh TL. PMID: 7912480.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    416. Transient spinal ischemia in the rat: characterization of behavioral and histopathological consequences as a function of the duration of aortic occlusion. J Cereb Blood Flow Metab. 1994 May; 14(3):526-35. Marsala M, Yaksh TL. PMID: 8163596.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    417. Antinociception produced by spinal delivery of the S and R enantiomers of flurbiprofen in the formalin test. Eur J Pharmacol. 1994 Apr 21; 256(2):205-9. Malmberg AB, Yaksh TL. PMID: 8050472.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    418. Nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea. J Appl Physiol (1985). 1994 Apr; 76(4):1651-6. Jinno S, Hua XY, Yaksh TL. PMID: 8045845.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    419. Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat. Anesthesiology. 1994 Feb; 80(2):383-91; discussion 25A. Abram SE, Yaksh TL. PMID: 8311320.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    420. Release of beta-endorphin and methionine-enkephalin into cerebrospinal fluid during deep brain stimulation for chronic pain. Effects of stimulation locus and site of sampling. J Neurosurg. 1993 Dec; 79(6):816-25. Young RF, Bach FW, Van Norman AS, Yaksh TL. PMID: 8246048.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    421. Impaired induction of vasoactive intestinal polypeptide after sciatic nerve injury in the streptozotocin-diabetic rat. J Neurol Sci. 1993 Nov; 119(2):154-61. Calcutt NA, Mizisin AP, Yaksh TL. PMID: 8277329.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    422. Effects of colchicine applied to the peripheral nerve on the thermal hyperalgesia evoked with chronic nerve constriction. Pain. 1993 Nov; 55(2):227-233. Yamamoto T, Yaksh TL. PMID: 7508592.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    423. Anti-nociceptive effects of the GM1 ganglioside derivative AGF 44 on the formalin test in normal and streptozotocin-diabetic rats. Neurosci Lett. 1993 Oct 14; 161(1):45-8. Malmberg AB, Yaksh TL, Calcutt NA. PMID: 8255545.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    424. Another call for patience instead of patients. Developing novel therapies for chronic pain. Anesthesiology. 1993 Oct; 79(4):637-40. Foley KM, Yaksh TL. PMID: 8214741.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    425. Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats. Pain. 1993 Sep; 54(3):291-300. Malmberg AB, Yaksh TL. PMID: 8233543.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    426. Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50488H, and L-PIA on the formalin test and an isobolographic analysis of the NSAID interaction. Anesthesiology. 1993 Aug; 79(2):270-81. Malmberg AB, Yaksh TL. PMID: 8102041.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    427. Suppression of nociceptive responses by spinal mu opioid agonists: effects of stimulus intensity and agonist efficacy. Anesth Analg. 1993 Aug; 77(2):265-74. Saeki S, Yaksh TL. PMID: 8346825.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    428. Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801. Pain. 1993 Jul; 54(1):79-84. Yamamoto T, Yaksh TL. PMID: 8378105.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    429. Effect of ibuprofen on regional eicosanoid production and neuronal injury after forebrain ischemia in rats. Brain Res. 1993 Jun 18; 614(1-2):315-24. Patel PM, Drummond JC, Sano T, Cole DJ, Kalkman CJ, Yaksh TL. PMID: 8348324.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    430. Dose-dependent antagonism of spinal opioid receptor agonists by naloxone and naltrindole: additional evidence for delta-opioid receptor subtypes in the rat. Eur J Pharmacol. 1993 May 12; 236(1):89-96. Tiseo PJ, Yaksh TL. PMID: 8391455.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    431. Pharmacology of the effects of bradykinin, serotonin, and histamine on the release of calcitonin gene-related peptide from C-fiber terminals in the rat trachea. J Neurosci. 1993 May; 13(5):1947-53. Hua XY, Yaksh TL. PMID: 8478685; PMCID: PMC6576580.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    432. Morphine, but not inhalation anesthesia, blocks post-injury facilitation. The role of preemptive suppression of afferent transmission. Anesthesiology. 1993 Apr; 78(4):713-21. Abram SE, Yaksh TL. PMID: 8385425.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    433. New horizons in our understanding of the spinal physiology and pharmacology of pain processing. Semin Oncol. 1993 Apr; 20(2 Suppl 1):6-18. Yaksh TL. PMID: 8475414.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    434. The spinal pharmacology of facilitation of afferent processing evoked by high-threshold afferent input of the postinjury pain state. Curr Opin Neurol Neurosurg. 1993 Apr; 6(2):250-6. Yaksh TL. PMID: 8097639.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    435. Caffeine as an analgesic adjuvant: a review of pharmacology and mechanisms of action. Pharmacol Rev. 1993 Mar; 45(1):43-85. Sawynok J, Yaksh TL. PMID: 8475169.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    436. Release of calcitonin gene-related peptide (CGRP), substance P (SP), and vasoactive intestinal polypeptide (VIP) from rat spinal cord: modulation by alpha 2 agonists. Peptides. 1993 Mar-Apr; 14(2):371-8. Takano M, Takano Y, Yaksh TL. PMID: 7683402.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    437. The role of focal nerve ischemia and Wallerian degeneration in peripheral nerve injury producing hyperesthesia. Anesthesiology. 1993 Feb; 78(2):308-16. Myers RR, Yamamoto T, Yaksh TL, Powell HC. PMID: 8439027.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    438. Spinal actions of NSAIDS in blocking spinally mediated hyperalgesia: the role of cyclooxygenase products. Agents Actions Suppl. 1993; 41:89-100. Yaksh TL, Malmberg AB. PMID: 8317344.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    439. Toxicology of baclofen continuously infused into the spinal intrathecal space of the dog. Neurotoxicology. 1993; 14(4):397-410. Sabbe MB, Grafe MR, Pfeifer BL, Mirzai TH, Yaksh TL. PMID: 8164885.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    440. Chronic spinal infusion of dexmedetomidine, ST-91 and clonidine: spinal alpha 2 adrenoceptor subtypes and intrinsic activity. J Pharmacol Exp Ther. 1993 Jan; 264(1):327-35. Takano Y, Yaksh TL. PMID: 8093729.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    441. Effects of intrathecal capsaicin and an NK-1 antagonist, CP,96-345, on the thermal hyperalgesia observed following unilateral constriction of the sciatic nerve in the rat. Pain. 1992 Dec; 51(3):329-334. Yamamoto T, Yaksh TL. PMID: 1337198.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    442. Interaction of intrathecal morphine with bupivacaine and lidocaine in the rat. Anesthesiology. 1992 Dec; 77(6):1186-2000. Penning JP, Yaksh TL. PMID: 1466469.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    443. The effect of cyclohexyladenosine on the periischemic increases of hippocampal glutamate and glycine in the rabbit. J Neurochem. 1992 Nov; 59(5):1884-92. Cantor SL, Zornow MH, Miller LP, Yaksh TL. PMID: 1357102.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    444. Isobolographic and dose-response analyses of the interaction between intrathecal mu and delta agonists: effects of naltrindole and its benzofuran analog (NTB). J Pharmacol Exp Ther. 1992 Oct; 263(1):264-75. Malmberg AB, Yaksh TL. PMID: 1328610.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    445. Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat. J Pharmacol Exp Ther. 1992 Oct; 263(1):136-46. Malmberg AB, Yaksh TL. PMID: 1403779.
      View in: PubMed   Mentions: 96     Fields:    Translation:Animals
    446. Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology. 1992 Oct; 77(4):757-63. Yamamoto T, Yaksh TL. PMID: 1416174.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    447. The effect of intrathecally administered imiloxan and WB4101: possible role of alpha 2-adrenoceptor subtypes in the spinal cord. Eur J Pharmacol. 1992 Sep 04; 219(3):465-8. Takano Y, Takano M, Yaksh TL. PMID: 1358645.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    448. Anesthesia and muscle relaxation with intrathecal injections of AR636 and AG489, two acylpolyamine spider toxins, in rat. Anesthesiology. 1992 Sep; 77(3):507-12. Herold EE, Yaksh TL. PMID: 1519789.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    449. Liposome encapsulation prolongs alfentanil spinal analgesia and alters systemic redistribution in the rat. Anesthesiology. 1992 Sep; 77(3):529-35. Bernards CM, Luger TJ, Malmberg AB, Hill HF, Yaksh TL. PMID: 1519790.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    450. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science. 1992 Aug 28; 257(5074):1276-9. Malmberg AB, Yaksh TL. PMID: 1381521.
      View in: PubMed   Mentions: 99     Fields:    
    451. Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats. J Pharmacol Exp Ther. 1992 May; 261(2):764-72. Takano Y, Yaksh TL. PMID: 1349648.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    452. Adrenal medullary secretion with splanchnic stimulation in spinal cats. J Auton Nerv Syst. 1992 May 01; 38(2):105-16. Stoddard SL, Tyce GM, Cook JA, Gaumann DM, Yaksh TL. PMID: 1619210.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    453. Use of 2-hydroxypropyl-beta-cyclodextrin as an intrathecal drug vehicle with opioids. J Pharmacol Exp Ther. 1992 May; 261(2):592-600. Jang J, Yaksh TL, Hill HF. PMID: 1349642.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    454. Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists. Pain. 1992 Apr; 49(1):121-128. Yamamoto T, Yaksh TL. PMID: 1594273.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    455. Studies of morphine and D-ala2-D-leu5-enkephalin (DADLE) cross-tolerance after continuous intrathecal infusion in the rat. Anesthesiology. 1992 Apr; 76(4):596-603. Stevens CW, Yaksh TL. PMID: 1550284.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    456. Suppression by spinal alpha-2 agonists of motor and autonomic responses evoked by low- and high-intensity thermal stimuli. J Pharmacol Exp Ther. 1992 Feb; 260(2):795-802. Saeki S, Yaksh TL. PMID: 1346645.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    457. Studies on the spinal interaction of morphine and the NMDA antagonist MK-801 on the hyperesthesia observed in a rat model of sciatic mononeuropathy. Neurosci Lett. 1992 Jan 20; 135(1):67-70. Yamamoto T, Yaksh TL. PMID: 1311824.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    458. The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis. Brain Res. 1992 Jan 13; 569(2):255-67. Jensen TS, Yaksh TL. PMID: 1347242.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    459. Brainstem excitatory amino acid receptors in nociception: microinjection mapping and pharmacological characterization of glutamate-sensitive sites in the brainstem associated with algogenic behavior. Neuroscience. 1992; 46(3):535-47. Jensen TS, Yaksh TL. PMID: 1347650.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    460. Release of calcitonin gene-related peptide and tachykinins from the rat trachea. Peptides. 1992 Jan-Feb; 13(1):113-20. Hua XY, Yaksh TL. PMID: 1377821.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    461. Comparison of the neurochemistry of the endogenous opioid systems in two brainstem pain-processing centers. Stereotact Funct Neurosurg. 1992; 59(1-4):15-9. al-Rodhan NR, Yaksh TL, Kelly PJ. PMID: 1295034.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    462. Spinal pharmacology of thermal hyperesthesia induced by incomplete ligation of sciatic nerve. I. Opioid and nonopioid receptors. Anesthesiology. 1991 Nov; 75(5):817-26. Yamamoto T, Yaksh TL. PMID: 1659256.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    463. Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain. J Neurochem. 1991 Oct; 57(4):1370-9. Baker AJ, Zornow MH, Scheller MS, Yaksh TL, Skilling SR, Smullin DH, Larson AA, Kuczenski R. PMID: 1895110.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    464. Structure-antinociceptive activity of neurotensin and some novel analogues in the periaqueductal gray region of the brainstem. Brain Res. 1991 Aug 23; 557(1-2):227-35. al-Rodhan NR, Richelson E, Gilbert JA, McCormick DJ, Kanba KS, Pfenning MA, Nelson A, Larson EW, Yaksh TL. PMID: 1660754.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    465. Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible antagonist. J Pharmacol Exp Ther. 1991 Aug; 258(2):438-46. Takano Y, Yaksh TL. PMID: 1678011.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    466. Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists. J Pharmacol Exp Ther. 1991 Aug; 258(2):544-50. Mjanger E, Yaksh TL. PMID: 1650833.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    467. The antinociceptive effects of spinally administered neuropeptide Y in the rat: systematic studies on structure-activity relationship. J Pharmacol Exp Ther. 1991 Jul 01; 258(1):243-8. Hua XY, Boublik JH, Spicer MA, Rivier JE, Brown MR, Yaksh TL. PMID: 1677040.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    468. Effects of [N-(L-(1-carboxy-2-phenyl)ethyl]-L-phenylalanyl-beta-alanine (SCH32615), a neutral endopeptidase (enkephalinase) inhibitor, on levels of enkephalin, encrypted enkephalins and substance P in cerebrospinal fluid and plasma of primates. J Pharmacol Exp Ther. 1991 Mar; 256(3):1033-41. Yaksh TL, Sabbe MB, Lucas D, Mjanger E, Chipkin RE. PMID: 1706428.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    469. Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia. JPEN J Parenter Enteral Nutr. 1991 Mar-Apr; 15(2):152-8. Murray MJ, Svingen BA, Holman RT, Yaksh TL. PMID: 1904949.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    470. Leakage of fluid after epidural injection. Pain. 1991 Mar; 44(3):325. Yaksh TL. PMID: 2052401.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    471. Nicotinic- and muscarinic-evoked release of canine adrenal catecholamines and peptides. Am J Physiol. 1991 Mar; 260(3 Pt 2):R589-99. Chritton SL, Dousa MK, Yaksh TL, Tyce GM. PMID: 2001009.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    472. Antinociceptive properties of intrathecal dexmedetomidine in rats. Eur J Pharmacol. 1991 Jan 10; 192(2):221-5. Fisher B, Zornow MH, Yaksh TL, Peterson BM. PMID: 1674472.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    473. Stereospecific effects of a nonpeptidic NK1 selective antagonist, CP-96,345: antinociception in the absence of motor dysfunction. Life Sci. 1991; 49(26):1955-63. Yamamoto T, Yaksh TL. PMID: 1721102.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    474. The utility of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs. Life Sci. 1991; 48(7):623-33. Yaksh TL, Jang JD, Nishiuchi Y, Braun KP, Ro SG, Goodman M. PMID: 1703620.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    475. Differential cross-tolerance between intrathecal morphine and sufentanil in the rat. Anesthesiology. 1990 Dec; 73(6):1141-7. Sosnowski M, Yaksh TL. PMID: 1978988.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    476. Pharmacology of intrathecal adrenergic agonists: cardiovascular and nociceptive reflexes in halothane-anesthetized rats. Anesthesiology. 1990 Dec; 73(6):1198-207. Nagasaka H, Yaksh TL. PMID: 1978989.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    477. Release in vivo of Met-enkephalin and encrypted forms of Met-enkephalin from brain and spinal cord of the anesthetized cat. Peptides. 1990 Nov-Dec; 11(6):1119-25. Lucas D, Yaksh TL. PMID: 2087436.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    478. Distribution of galanin-like immunoreactivity in the pig, rat and human central nervous system. Peptides. 1990 Nov-Dec; 11(6):1217-23. Michener SR, Aimone LD, Yaksh TL, Go VL. PMID: 1708138.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    479. Alpha-chloralose anesthesia inhibits the somato-sympathetic reflex response in cats more effectively than halothane. Zentralbl Veterinarmed A. 1990 Oct; 37(9):669-75. Gaumann DM, Yaksh TL. PMID: 2127972.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    480. Demonstration of intrathecal and systemic morphine and ST-91 effects on fed canine upper gut motility. Dig Dis Sci. 1990 Oct; 35(10):1249-56. Thomforde GM, Malagelada JR, Camilleri M, Yaksh TL. PMID: 1976496.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    481. Effects of intrathecal morphine, clonidine, and midazolam on the somato-sympathoadrenal reflex response in halothane-anesthetized cats. Anesthesiology. 1990 Sep; 73(3):425-32. Gaumann DM, Yaksh TL, Tyce GM. PMID: 2393126.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    482. Cryptic Met-enkephalin in adrenal and portal vein during splanchnic artery occlusion shock in cats. Neurosci Lett. 1990 Aug 24; 116(3):387-92. Gaumann DM, Yaksh TL, Lucas DL. PMID: 2243619.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    483. Interaction of intrathecal morphine and ST-91 on antinociception in the rat: dose-response analysis, antagonism and clearance. J Pharmacol Exp Ther. 1990 Aug; 254(2):383-92. Monasky MS, Zinsmeister AR, Stevens CW, Yaksh TL. PMID: 1974633.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    484. Distribution of neuropeptide Y in the spinal cords of cat, dog, rat, man and pig. Regul Pept. 1990 Jul 30; 29(2-3):81-92. Roddy DR, Yaksh TL, Aimone LD, Go VL. PMID: 2217906.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    485. The antinociceptive effects of SCH-32615, a neutral endopeptidase (enkephalinase) inhibitor, microinjected into the periaqueductal, ventral medulla and amygdala. Brain Res. 1990 Jun 18; 520(1-2):123-30. al-Rodhan N, Chipkin R, Yaksh TL. PMID: 2207626.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    486. The role of spinal and brainstem adenosine receptors in the modulation of the volume-evoked micturition reflex in the unanesthetized rat. Brain Res. 1990 May 07; 515(1-2):207-13. Sosnowski M, Yaksh TL. PMID: 2357559.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    487. The antinociceptive effects of intrathecally administered SCH32615, an enkephalinase inhibitor in the rat. Brain Res. 1990 May 07; 515(1-2):143-8. Oshita S, Yaksh TL, Chipkin R. PMID: 2357551.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    488. The analgesic interaction between intrathecal morphine, lidocaine and bupivacaine in the rat. Can J Anaesth. 1990 May; 37(4 Pt 2):S48. Penning JP, Yaksh TL. PMID: 2361295.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    489. Intrathecal morphine and bupivacaine in the rat; analgesic synergy without augmentation of motor dysfunction or hypotension. Can J Anaesth. 1990 May; 37(4 Pt 2):S49. Penning JP, Nagasaka H, Yaksh TL. PMID: 2361296.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    490. Interaction of midazolam and morphine in the spinal cord of the rat. Neuropharmacology. 1990 Apr; 29(4):359-64. Yanez A, Sabbe MB, Stevens CW, Yaksh TL. PMID: 2160622.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    491. Measurement of lumbar CSF levels of met-enkephalin, encrypted met-enkephalin, and neuropeptide Y in normal patients and in patients with Parkinson's disease before and after autologous transplantation of adrenal medulla into the caudate nucleus. J Lab Clin Med. 1990 Mar; 115(3):346-51. Yaksh TL, Carmichael SW, Stoddard SL, Tyce GM, Kelly PJ, Lucas D, van Heerden JA, Ahlskog JE, Byer DE. PMID: 2313164.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    492. The antiseizure activity of dihydropyridine calcium channel antagonists in the conscious rat. J Pharmacol Exp Ther. 1990 Mar; 252(3):1150-5. Morón MA, Stevens CW, Yaksh TL. PMID: 2319465.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    493. Sites in the brain at which cholecystokinin octapeptide (CCK-8) acts to suppress feeding in rats: a mapping study. Neuropharmacology. 1990 Feb; 29(2):109-18. Schick RR, Harty GJ, Yaksh TL, Go VL. PMID: 2330072.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    494. Long-term pain relief produced by intrathecal morphine infusion in 53 patients. J Neurosurg. 1990 Feb; 72(2):200-9. Onofrio BM, Yaksh TL. PMID: 1688618.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    495. Epidural and intrathecal administration of sufentanil, alfentanil and morphine in the dog: a comparison of analgesic effects and the development of tolerance. NIDA Res Monogr. 1990; 105:560. Tiseo PJ, Sabbe MB, Yaksh TL. PMID: 1831544.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    496. Systematic studies on the effects of the NMDA receptor antagonist MK-801 on cerebral blood flow and responsivity, EEG, and blood-brain barrier following complete reversible cerebral ischemia. J Cereb Blood Flow Metab. 1990 Jan; 10(1):77-88. Stevens MK, Yaksh TL. PMID: 2153692.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    497. The secretion of catecholamines, chromogranin A and neuropeptide Y from the adrenal medulla of the cat via the adrenolumbar vein and thoracic duct: different anatomic routes based on size. Neuroscience. 1990; 34(2):433-40. Carmichael SW, Stoddard SL, O'Connor DT, Yaksh TL, Tyce GM. PMID: 2333152.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    498. The spinal pharmacology of urinary function: studies on urinary continence in the unanaesthetized rat. Ciba Found Symp. 1990; 151:91-104; discussion 104-9. Tiseo PJ, Yaksh TL. PMID: 1699710.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    499. Intrathecal somatostatin, somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats. Neuroscience. 1990; 39(3):761-74. Gaumann DM, Grabow TS, Yaksh TL, Casey SJ, Rodriguez M. PMID: 1711172.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    500. Segmental analysis of neuropeptide concentrations in normal human spinal cord. Neurology. 1990 Jan; 40(1):137-44. Benarroch EE, Aimone LD, Yaksh TL. PMID: 2296359.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    501. Effects of sufentanil and naltrexone on adrenal vein catecholamines and neuropeptides during splanchnic nerve stimulation in cats. Synapse. 1990; 6(4):392-4. Gaumann DM, Yaksh TL, Tyce GM. PMID: 2149618.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    502. Role of spinal adenosine receptors in modulating the hyperesthesia produced by spinal glycine receptor antagonism. Anesth Analg. 1989 Nov; 69(5):587-92. Sosnowski M, Yaksh TL. PMID: 2552866.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    503. Opioid modulation of capsaicin-evoked release of substance P from rat spinal cord in vivo. Peptides. 1989 Nov-Dec; 10(6):1127-31. Aimone LD, Yaksh TL. PMID: 2482963.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    504. Time course characteristics of tolerance development to continuously infused antinociceptive agents in rat spinal cord. J Pharmacol Exp Ther. 1989 Oct; 251(1):216-23. Stevens CW, Yaksh TL. PMID: 2795458.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    505. Assessment of the role of A1/A2 adenosine receptors mediating the purine antinociception, motor and autonomic function in the rat spinal cord. J Pharmacol Exp Ther. 1989 Sep; 250(3):915-22. Sosnowski M, Stevens CW, Yaksh TL. PMID: 2778719.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    506. Studies on the effect of SCH-34826 and thiorphan on [Met5]enkephalin levels and release in rat spinal cord. Eur J Pharmacol. 1989 Aug 29; 167(3):367-73. Yaksh TL, Chipkin RE. PMID: 2806377.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    507. Magnitude of opioid dependence after continuous intrathecal infusion of mu- and delta-selective opioids in the rat. Eur J Pharmacol. 1989 Aug 03; 166(3):467-72. Stevens CW, Yaksh TL. PMID: 2553435.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    508. Catecholamines in CSF, plasma, and tissue after autologous transplantation of adrenal medulla to the brain in patients with Parkinson's disease. J Lab Clin Med. 1989 Aug; 114(2):185-92. Tyce GM, Ahlskog JE, Carmichael SW, Chritton SL, Stoddard SL, van Heerden JA, Yaksh TL, Kelly PJ. PMID: 2754305.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    509. Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion. J Pharmacol Exp Ther. 1989 Jul; 250(1):1-8. Stevens CW, Yaksh TL. PMID: 2526212.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    510. Cerebrospinal fluid calcium homeostasis: evidence for a plasma membrane Ca2+-pump in mammalian choroid plexus. Brain Res. 1989 Jun 12; 489(2):355-60. Borke JL, Caride AJ, Yaksh TL, Penniston JT, Kumar R. PMID: 2525946.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    511. Electroencephalographic and behavioral assessment of intracerebroventricular somatostatin and a substance P analogue. Brain Res. 1989 Jun 12; 489(2):223-30. Grabow TS, Gaumann DM, Yaksh TL. PMID: 2472857.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    512. Intrathecal somatostatin in cat and mouse studies on pain, motor behavior, and histopathology. Anesth Analg. 1989 May; 68(5):623-32. Gaumann DM, Yaksh TL, Post C, Wilcox GL, Rodriguez M. PMID: 2566288.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    513. Adrenal vein catecholamines and neuropeptides during splanchnic nerve stimulation in cats. Peptides. 1989 May-Jun; 10(3):587-92. Gaumann DM, Yaksh TL, Tyce GM, Stoddard SL. PMID: 2780418.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    514. Diltiazem enhances and flunarizine inhibits nimodipine's antiseizure effects. Eur J Pharmacol. 1989 Apr 25; 163(2-3):299-307. Morón MA, Stevens CW, Yaksh TL. PMID: 2721577.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    515. Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists. Pain. 1989 Apr; 37(1):111-123. Yaksh TL. PMID: 2542867.
      View in: PubMed   Mentions: 167     Fields:    Translation:Animals
    516. Effects of cervical spinal hemisection on dihydromorphine binding in brainstem and spinal cord in cat. Brain Res. 1989 Mar 27; 483(1):61-7. Ramberg DA, Yaksh TL. PMID: 2539891.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    517. Quantitation of endogenous substance P by on-line microcolumn liquid chromatography/continuous-flow fast-atom bombardment mass spectrometry. Rapid Commun Mass Spectrom. 1989 Feb; 3(2):43-6. Lisek CA, Bailey JE, Benson LM, Yaksh TL, Jardine I. PMID: 2485177.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    518. Adrenal vein catecholamines and met-enkephalin during staged hemorrhage and naltrexone administration in cats. Circ Shock. 1989 Feb; 27(2):139-54. Gaumann DM, Yaksh TL, Dousa MK, Tyce GM. PMID: 2539919.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    519. Comparison of the antinociceptive effect of morphine and glutamate at coincidental sites in the periaqueductal gray and medial medulla in rats. Brain Res. 1989 Jan 02; 476(1):1-9. Jensen TS, Yaksh TL. PMID: 2563331.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    520. Opioid dependence after continuous intrathecal infusion of mu and delta opioids in the rat. NIDA Res Monogr. 1989; 95:544-5. Stevens CW, Yaksh TL. PMID: 2577051.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    521. Physiologic and plasma hormone correlates of survival in endotoxic dogs: effects of opiate antagonists. Crit Care Med. 1989 Jan; 17(1):39-47. Murray MJ, Offord KP, Yaksh TL. PMID: 2535799.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    522. Studies in animals should precede human use of spinally administered drugs. Anesthesiology. 1989 Jan; 70(1):4-6. Yaksh TL, Collins JG. PMID: 2912314.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    523. Effects of thoracic aortic occlusion and cerebrospinal fluid drainage on regional spinal cord blood flow in dogs: correlation with neurologic outcome. J Vasc Surg. 1989 Jan; 9(1):135-44. Bower TC, Murray MJ, Gloviczki P, Yaksh TL, Hollier LH, Pairolero PC. PMID: 2911133.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    524. Adrenal and intestinal secretion of catecholamines and neuropeptides during splanchnic artery occlusion shock. Circ Shock. 1988 Dec; 26(4):391-407. Gaumann DM, Yaksh TL. PMID: 3214933.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    525. Time course of release in vivo of PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 into the brain extracellular space after 15 min of complete global ischemia in the presence and absence of cyclooxygenase inhibition. J Cereb Blood Flow Metab. 1988 Dec; 8(6):790-8. Stevens MK, Yaksh TL. PMID: 3142890.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    526. Release of prostaglandin E2 from brain of cat: II. In vivo studies on the effects of adrenergic, cholinergic and dopaminergic agonists and antagonists. Neuropharmacology. 1988 Oct; 27(10):1067-72. Navarro E, Romero SD, Yaksh TL. PMID: 2907118.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    527. Concurrent separation of catecholamines, dihydroxyphenylglycol, vasoactive intestinal peptide, and neuropeptide Y in superfusate and tissue extract. Anal Biochem. 1988 Sep; 173(2):340-52. Hunter LW, Rorie DK, Yaksh TL, Tyce GM. PMID: 3189813.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    528. Substance P release from knee joint afferent terminals: modulation by opioids. Brain Res. 1988 Aug 23; 458(2):319-24. Yaksh TL. PMID: 2463049.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    529. Sympathetic stimulating effects of sufentanil in the cat are mediated centrally. Neurosci Lett. 1988 Aug 15; 91(1):30-5. Gaumann DM, Yaksh TL, Tyce GM, Stoddard S. PMID: 2845307.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    530. Effect of acute and chronic spinal transection on evoked secretion of adrenal medullary catecholamines in the cat. J Auton Nerv Syst. 1988 Aug; 23(2):175-9. Stoddard SL, Tyce GM, Carmichael SW, Gaumann DM, Yaksh TL. PMID: 3171091.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    531. Micturition in the unanesthetized rat: effects of intrathecal capsaicin, N-vanillylnonanamide, 6-hydroxydopamine and 5,6-dihydroxytryptamine. Brain Res. 1988 Jun 07; 451(1-2):301-8. Durant PA, Yaksh TL. PMID: 3150817.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    532. Chronic intraventricular administration of cholecystokinin octapeptide (CCK-8) suppresses feeding in rats. Brain Res. 1988 May 17; 448(2):294-8. Schick RR, Stevens CW, Yaksh TL, Go VL. PMID: 3378151.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    533. Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system. J Pharmacol Exp Ther. 1988 May; 245(2):426-35. Durant PA, Lucas PC, Yaksh TL. PMID: 3367300.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    534. Intrathecal somatostatin in rats: antinociception only in the presence of toxic effects. Anesthesiology. 1988 May; 68(5):733-42. Gaumann DM, Yaksh TL. PMID: 2897175.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    535. Opioids preserve the adrenal medullary response evoked by severe hemorrhage: studies on adrenal catecholamine and met-enkephalin secretion in halothane anesthetized cats. Anesthesiology. 1988 May; 68(5):743-53. Gaumann DM, Yaksh TL, Tyce GM, Lucas DL. PMID: 2835918.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    536. Survey of distribution of substance P, vasoactive intestinal polypeptide, cholecystokinin, neurotensin, Met-enkephalin, bombesin and PHI in the spinal cord of cat, dog, sloth and monkey. Peptides. 1988 Mar-Apr; 9(2):357-72. Yaksh TL, Michener SR, Bailey JE, Harty GJ, Lucas DL, Nelson DK, Roddy DR, Go VL. PMID: 2453858.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    537. Drug effects on urinary bladder tone during spinal morphine-induced inhibition of the micturition reflex in unanesthetized rats. Anesthesiology. 1988 Mar; 68(3):325-34. Durant PA, Yaksh TL. PMID: 3344988.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    538. Effects of hemorrhage and opiate antagonists on adrenal release of neuropeptides in cats. Peptides. 1988 Mar-Apr; 9(2):393-405. Gaumann DM, Yaksh TL. PMID: 3375139.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    539. Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine. J Pharmacol Exp Ther. 1988 Feb; 244(2):501-7. Yaksh TL, Harty GJ. PMID: 3346833.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    540. Decreased catecholamines in the adrenal medulla of patients with parkinsonism. N Engl J Med. 1988 Jan 28; 318(4):254. Carmichael SW, Wilson RJ, Brimijoin WS, Melton LJ, Okazaki H, Yaksh TL, Ahlskog JE, Stoddard SL, Tyce GM. PMID: 3336415.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    541. Receptors in the dorsal horn and intrathecal drug administration. Ann N Y Acad Sci. 1988; 531:90-107. Yaksh TL, Gaumann DM, Stevens CW. PMID: 2898231.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    542. Opioid and adrenergic spinal receptor systems and pain control. NIDA Res Monogr. 1988; 81:343-52. Stevens C, Yaksh T. PMID: 2841603.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    543. CNS mechanisms of pain and analgesia. Cancer Surv. 1988; 7(1):5-28. Yaksh TL. PMID: 2838170.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    544. Spinal infusion of opiate and alpha-2 agonists in rats: tolerance and cross-tolerance studies. J Pharmacol Exp Ther. 1988 Jan; 244(1):63-70. Stevens CW, Monasky MS, Yaksh TL. PMID: 2891846.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    545. Sites of action of opiates in production of analgesia. Prog Brain Res. 1988; 77:371-94. Yaksh TL, Al-Rodhan NR, Jensen TS. PMID: 2851148.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    546. Chronic antagonist infusion does not increase morphine antinociception in rat spinal cord. Brain Res. 1987 Nov 10; 425(2):388-90. Stevens CW, Yaksh TL. PMID: 3427441.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    547. Retrospective consideration of the doses of morphine given intrathecally by chronic infusion in 163 patients by 19 physicians. Pain. 1987 Nov; 31(2):211-223. Yaksh TL, Onofrio BM. PMID: 3431881.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    548. Effects of hemorrhage and naloxone on adrenal release of methionine-enkephalin and catecholamines in halothane anesthetized dogs. J Auton Nerv Syst. 1987 Nov; 21(1):29-41. Gaumann DM, Yaksh TL, Dousa MK, Tyce GM, Lucas DL, Hench VS. PMID: 3440817.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    549. Release of substance P from the cat spinal cord. J Physiol. 1987 Oct; 391:141-67. Go VL, Yaksh TL. PMID: 2451003; PMCID: PMC1192207.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    550. Neuronal cholecystokinin-like immunoreactivity is postprandially released from primate hypothalamus. Brain Res. 1987 Aug 18; 418(1):20-6. Schick RR, Reilly WM, Roddy DR, Yaksh TL, Go VL. PMID: 3664270.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    551. Opioid receptor systems and the endorphins: a review of their spinal organization. J Neurosurg. 1987 Aug; 67(2):157-76. Yaksh TL. PMID: 3037042.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    552. Production of uric acid in cerebrospinal fluid after subarachnoid hemorrhage in dogs: investigation of the possible role of xanthine oxidase in chronic vasospasm. Neurosurgery. 1987 Jul; 21(1):39-44. Kim P, Yaksh TL, Romero SD, Sundt TM. PMID: 3614602.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    553. The effect of unilateral dorsal root ganglionectomies or ventral rhizotomies on alpha 2-adrenoceptor binding to, and the substance P, enkephalin, and neurotensin content of, the cat lumbar spinal cord. Neuroscience. 1987 May; 21(2):385-94. Howe JR, Yaksh TL, Go VL. PMID: 2441314.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    554. Intrathecal 6-hydroxydopamine or cervical spinal hemisection reduces norepinephrine content, but not the density of alpha 2-adrenoceptors, in the cat lumbar spinal enlargement. Neuroscience. 1987 May; 21(2):377-84. Howe JR, Yaksh TL, Tyce GM. PMID: 3039400.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    555. Release of cholecystokinin from rat cerebral cortex in vivo: role of GABA and glutamate receptor systems. Brain Res. 1987 Mar 17; 406(1-2):207-14. Yaksh TL, Furui T, Kanawati IS, Go VL. PMID: 3032357.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    556. Spinal antinociceptive action of three representative opioid peptides in frogs. Brain Res. 1987 Jan 27; 402(1):201-3. Stevens CW, Pezalla PD, Yaksh TL. PMID: 2881600.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    557. Cerebrospinal fluid levels of uric acid in dogs and the effect of allopurinol. Brain Res. 1987 Jan 27; 402(1):87-92. Kim P, Yaksh TL, Burnett PC, Blum MR, Sundt TM. PMID: 3828791.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    558. Issues in drug management. Part 2. The use of receptor-selective agents as analgesics in the spinal cord: trends and possibilities. J Pain Symptom Manage. 1987; 2(3):129-38. Yaksh TL, Durant PA, Gaumann DM, Stevens CW, Mjanger E. PMID: 3039016.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    559. Spinal opiates: a review of their effect on spinal function with emphasis on pain processing. Acta Anaesthesiol Scand Suppl. 1987; 85:25-37. Yaksh TL. PMID: 2821725.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    560. Effect of preischemia cyclooxygenase inhibition by zomepirac sodium on reflow, cerebral autoregulation, and EEG recovery in the cat after global ischemia. J Cereb Blood Flow Metab. 1986 Dec; 6(6):691-702. Stevens MK, Yaksh TL, Hansen RB, Anderson RE. PMID: 3098746.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    561. Cardiorespiratory effects and kinetics of intrathecally injected D-Ala2-D-Leu5-enkephalin and morphine in unanesthetized dogs. Anesthesiology. 1986 Dec; 65(6):609-16. Atchison SR, Durant PA, Yaksh TL. PMID: 3098139.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    562. Spinal action of dermorphin, an extremely potent opioid peptide from frog skin. Brain Res. 1986 Oct 22; 385(2):300-4. Stevens CW, Yaksh TL. PMID: 2877713.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    563. Studies on the effects of intrathalamically injected DADL and morphine on nociceptive thresholds and electroencephalographic activity: a thalamic delta receptor syndrome. Brain Res. 1986 Sep 24; 383(1-2):1-14. Walker GE, Yaksh TL. PMID: 3021275.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    564. Dynorphin A and related peptides administered intrathecally in the rat: a search for putative kappa opiate receptor activity. J Pharmacol Exp Ther. 1986 Sep; 238(3):833-8. Stevens CW, Yaksh TL. PMID: 2875172.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    565. Simple catheter preparation for permitting bolus intrathecal administration during chronic intrathecal infusion. Pharmacol Biochem Behav. 1986 Aug; 25(2):483-5. Yaksh TL, Stevens CW. PMID: 3763669.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    566. Amine sulfate formation in the central nervous system. Fed Proc. 1986 Jul; 45(8):2247-53. Tyce GM, Messick JM, Yaksh TL, Byer DE, Danielson DR, Rorie DK. PMID: 3459671.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    567. Distribution in cerebrospinal fluid, blood, and lymph of epidurally injected morphine and inulin in dogs. Anesth Analg. 1986 Jun; 65(6):583-92. Durant PA, Yaksh TL. PMID: 3706799.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    568. Conjugates of biogenic amines in ventriculocisternal perfusates of conscious African green monkeys. Brain Res. 1986 May 07; 372(2):269-76. Tyce GM, Yaksh TL. PMID: 3708364.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    569. Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique. Brain Res. 1986 May 07; 372(2):301-12. Jensen TS, Yaksh TL. PMID: 2871901.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    570. High dose of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: clinical and theoretic implications. Anesthesiology. 1986 May; 64(5):590-7. Yaksh TL, Harty GJ, Onofrio BM. PMID: 2938524.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    571. Characterization of [3H]rauwolscine binding to alpha 2-adrenoceptor sites in the lumbar spinal cord of the cat: comparison to such binding sites in the cat frontal cerebral cortex. Brain Res. 1986 Mar 12; 368(1):87-100. Howe JR, Yaksh TL. PMID: 2869820.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    572. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain Res. 1986 Mar 12; 368(1):107-15. Jeftinija S, Raspantini C, Randic M, Yaksh TL, Go VL, Larson AA. PMID: 2420413.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    573. Studies on the effects of opioid, noradrenergic and serotonergic antagonists on the antinociceptive effects of electroconvulsive shock. Brain Res. 1986 Mar 05; 367(1-2):162-8. Furui T, Harty GJ, Yaksh TL. PMID: 2870768.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    574. Effect in cat of locus coeruleus lesions on the response of cerebral blood flow and cardiac output to altered paCO2. Brain Res. 1986 Feb 19; 365(2):278-88. Reddy SV, Yaksh TL, Anderson RE, Sundt TM. PMID: 3004658.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    575. Bradycardia and hypotension associated with baclofen used during general anesthesia. Anesthesiology. 1986 Feb; 64(2):255-8. Sill JC, Schumacher K, Southorn PA, Reuter J, Yaksh TL. PMID: 3511771.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    576. Comparison of antinociceptive action of morphine in the periaqueductal gray, medial and paramedial medulla in rat. Brain Res. 1986 Jan 15; 363(1):99-113. Jensen TS, Yaksh TL. PMID: 3004644.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    577. Examination of spinal monoamine receptors through which brainstem opiate-sensitive systems act in the rat. Brain Res. 1986 Jan 15; 363(1):114-27. Jensen TS, Yaksh TL. PMID: 3004638.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    578. Development of experimental models for meningeal neoplasia using intrathecal injection of 9L gliosarcoma and Walker 256 carcinosarcoma in the rat. Cancer Res. 1986 Jan; 46(1):317-23. Kooistra KL, Rodriguez M, Powis G, Yaksh TL, Harty GJ, Hilton JF, Laws ER. PMID: 3753551.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    579. Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study. Anesthesiology. 1986 Jan; 64(1):43-53. Durant PA, Yaksh TL. PMID: 2867721.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    580. Immunochemical studies of substance P and cholecystokinin octapeptide recovery in dorsal horn following unilateral lumbosacral ganglionectomy. Somatosens Res. 1986; 3(3):239-60. Micevych PE, Stroink A, Yaksh T, Go VL. PMID: 2428085.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    581. Studies of the pharmacology and pathology of intrathecally administered 4-anilinopiperidine analogues and morphine in the rat and cat. Anesthesiology. 1986 Jan; 64(1):54-66. Yaksh TL, Noueihed RY, Durant PA. PMID: 2867722.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    582. The analgesic efficacy of intrathecal D-Ala2-D-Leu5-enkephalin in cancer patients with chronic pain. Pain. 1985 Nov; 23(3):213-221. Moulin DE, Max MB, Kaiko RF, Inturrisi CE, Maggard J, Yaksh TL, Foley KM. PMID: 3906516.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    583. Antinociceptive effects of intrathecally injected cholinomimetic drugs in the rat and cat. Eur J Pharmacol. 1985 Oct 29; 117(1):81-8. Yaksh TL, Dirksen R, Harty GJ. PMID: 3841316.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    584. Studies on spinal opiate receptor pharmacology. III. Analgetic effects of enkephalin dimers as measured by cutaneous-thermal and visceral-chemical evoked responses. Brain Res. 1985 Jul 01; 337(2):209-15. Schmauss C, Shimohigashi Y, Jensen TS, Rodbard D, Yaksh TL. PMID: 2992678.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    585. Effect of opiates on the release of cholecystokinin from in vitro hypothalamus and frontal cortex of Zucker lean (Fa/-) and obese (fa/fa) rats. Brain Res. 1985 Jul 01; 337(2):382-5. Micevych PE, Yaksh TL, Go VW, Finkelstein JA. PMID: 3896389.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    586. Characterization of the spinal adrenergic receptors mediating the spinal effects produced by the microinjection of morphine into the periaqueductal gray. Brain Res. 1985 Jun 10; 336(1):133-42. Camarata PJ, Yaksh TL. PMID: 2988700.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    587. Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing. Pharmacol Biochem Behav. 1985 May; 22(5):845-58. Yaksh TL. PMID: 2861606.
      View in: PubMed   Mentions: 98     Fields:    Translation:Animals
    588. Studies on the in vivo release of vasoactive intestinal polypeptide (VIP) from the cerebral cortex: effects of cortical, brainstem and somatic stimuli. Brain Res. 1985 Feb 11; 326(2):317-34. Wang JY, Yaksh TL, Go VL. PMID: 2982463.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    589. Efflux of 5-hydroxytryptamine and noradrenaline into spinal cord superfusates during stimulation of the rat medulla. J Physiol. 1985 Feb; 359:151-62. Hammond DL, Tyce GM, Yaksh TL. PMID: 2582112; PMCID: PMC1193369.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    590. The physiology and pharmacology of spinal opiates. Annu Rev Pharmacol Toxicol. 1985; 25:433-62. Yaksh TL, Noueihed R. PMID: 2988422.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    591. Measurement of prostaglandins in the cerebrospinal fluid in cat, dog, and man. J Neurochem. 1984 Dec; 43(6):1642-9. Romero SD, Chyatte D, Byer DE, Romero JC, Yaksh TL. PMID: 6593432.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    592. Spinal monoamine and opiate systems partly mediate the antinociceptive effects produced by glutamate at brainstem sites. Brain Res. 1984 Nov 12; 321(2):287-97. Jensen TS, Yaksh TL. PMID: 6149792.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    593. Multiple opioid receptor systems in brain and spinal cord: Part 2. Eur J Anaesthesiol. 1984 Sep; 1(3):201-43. Yaksh TL. PMID: 6152614.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    594. Action of intrathecal capsaicin and its structural analogues on the content and release of spinal substance P: selectivity of action and relationship to analgesia. Brain Res. 1984 Jul 23; 306(1-2):215-25. Jhamandas K, Yaksh TL, Harty G, Szolcsanyi J, Go VL. PMID: 6205719.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    595. Conjugates of dopamine and serotonin in ventriculocisternal perfusates of the cat. J Neurochem. 1984 Jun; 42(6):1752-7. Hammond DL, Yaksh TL, Tyce GM. PMID: 6726235.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    596. Multiple opioid receptor systems in brain and spinal cord: Part I. Eur J Anaesthesiol. 1984 Jun; 1(2):171-99. Yaksh TL. PMID: 6152613.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    597. Antagonism of stimulation-produced antinociception by intrathecal administration of methysergide or phentolamine. Brain Res. 1984 Apr 30; 298(2):329-37. Hammond DL, Yaksh TL. PMID: 6326954.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    598. Acute and chronic morphine modifies the in vivo release of methionine enkephalin-like immunoreactivity from the cat spinal cord and brain. Brain Res. 1984 Apr 09; 297(1):91-103. Jhamandas K, Yaksh TL, Go VL. PMID: 6722539.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    599. Effects of an intrathecal dopamine agonist, apomorphine, on thermal and chemical evoked noxious responses in rats. Brain Res. 1984 Apr 02; 296(2):285-93. Jensen TS, Yaksh TL. PMID: 6322926.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    600. Simultaneous measurement of cholecystokinin- and vasoactive intestinal polypeptide-like immunoreactivity from cat frontal cortex in vitro: effect of morphine and D-Ala2-D-Leu5-enkephalin. Brain Res. 1984 Jan 16; 291(1):55-62. Micevychi PE, Go VL, Yaksh TL. PMID: 6697185.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    601. Studies on the opiate receptor-mediated inhibition of K+-stimulated cholecystokinin and substance P release from cat hypothalamus in vitro. Brain Res. 1984 Jan 02; 290(1):87-94. Micevych PE, Yaksh TL, Go VL. PMID: 6198038.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    602. In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical and cutaneous thermal stimuli in the rat. J Pharmacol Exp Ther. 1984 Jan; 228(1):1-12. Schmauss C, Yaksh TL. PMID: 6319664.
      View in: PubMed   Mentions: 76     Fields:    Translation:Animals
    603. In vitro, release of cholecystokinin from hypothalamus and frontal cortex of Sprague-Dawley, Zucker lean (Fa/-) and obese (fa/fa) rats. Peptides. 1984 Jan-Feb; 5(1):73-80. Micevych PE, Go VL, Yaksh TL, Finkelstein J. PMID: 6200866.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    604. Effects of spinally administered agents on spinal cord blood flow: a need for further studies. Anesthesiology. 1983 Sep; 59(3):173-4. Yaksh TL. PMID: 6688331.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    605. In vivo studies on spinal opiate receptor systems mediating antinociception. I. Mu and delta receptor profiles in the primate. J Pharmacol Exp Ther. 1983 Aug; 226(2):303-16. Yaksh TL. PMID: 6308205.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    606. Concurrent measurement of substance P and serotonin in spinal superfusates: failure of capsaicin and p-chloroamphetamine to co-release. Brain Res. 1983 Jun 27; 270(1):181-4. Bergstrom L, Hammond DL, Go VL, Yaksh TL. PMID: 6191841.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    607. Intrathecal delta-receptor ligand produces analgesia in man. Lancet. 1983 Jun 18; 1(8338):1386-7. Onofrio BM, Yaksh TL. PMID: 6134164.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    608. Pharmacological antagonism of the antinociceptive effects of serotonin in the rat spinal cord. Eur J Pharmacol. 1983 Jun 17; 90(4):349-57. Schmauss C, Hammond DL, Ochi JW, Yaksh TL. PMID: 6688398.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    609. Spinal cord monoamines modulate the antinociceptive effects of vaginal stimulation in rats. Pain. 1983 Jun; 16(2):155-166. Steinman JL, Komisaruk BR, Yaksh TL, Tyce GM. PMID: 6877846.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    610. Studies on the release by somatic stimulation from rat and cat spinal cord of active materials which displace dihydromorphine in an opiate-binding assay. Brain Res. 1983 May 23; 268(1):119-28. Yaksh TL, Terenius L, Nyberg F, Jhamandas K, Wang JY. PMID: 6860955.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    611. Drug-induced alterations in the efflux of 5-hydroxytryptamine and of 5-hydroxyindoleacetic acid into superfusates of the rat spinal cord. Eur J Pharmacol. 1983 Mar 04; 87(4):441-8. Hammond DL, Tyce GM, Yaksh TL. PMID: 6189730.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    612. Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine. J Pharmacol Exp Ther. 1983 Mar; 224(3):552-8. Howe JR, Wang JY, Yaksh TL. PMID: 6131120.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    613. Effects on nociceptive threshold and blood pressure of intrathecally administered morphine and alpha-adrenergic agonists. Neuropharmacology. 1983 Mar; 22(3):309-15. Yasuoka S, Yaksh TL. PMID: 6133234.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    614. Effect of intrathecal capsaicin analogues on the immunofluorescence of peptides and serotonin in the dorsal horn in rats. Neuroscience. 1983 Jan; 8(1):123-31. Micevych PE, Yaksh TL, Szolcsanyi J. PMID: 6188075.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    615. Opioid activity released from cat spinal cord by sciatic nerve stimulation. Life Sci. 1983; 33 Suppl 1:17-20. Nyberg F, Yaksh TL, Terenius L. PMID: 6664216.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    616. Differential association of spinal mu, delta and kappa opioid receptors with cutaneous thermal and visceral chemical nociceptive stimuli in the rat. Life Sci. 1983; 33 Suppl 1:653-6. Schmauss C, Yaksh TL, Shimohigashi Y, Harty G, Jensen T, Rodbard D. PMID: 6319919.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    617. Spinal pharmacology of pain and its modulation. Clin Neurosurg. 1983; 31:291-303. Yaksh TL. PMID: 6209049.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    618. The analgetic effects of an intrathecally administered partial opiate agonist, nalbuphine hydrochloride. Eur J Pharmacol. 1982 Dec 17; 86(1):1-7. Schmauss C, Doherty C, Yaksh TL. PMID: 6897635.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    619. Opiate-mediated inhibition of the release of cholecystokinin and substance P, but not neurotensin from cat hypothalamic slices. Brain Res. 1982 Nov 04; 250(2):283-9. Micevych PE, Yaksh TL, Go VL. PMID: 6184121.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    620. In vivo evidence for multiple opiate receptors mediating analgesia in the rat spinal cord. Brain Res. 1982 Sep 09; 247(1):75-83. Tung AS, Yaksh TL. PMID: 6127147.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    621. Agonist regulation of muscarinic acetylcholine receptors in rat spinal cord. J Neurochem. 1982 Aug; 39(2):521-4. Taylor JE, Yaksh TL, Richelson E. PMID: 7086433.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    622. Histamine H1 receptors in the brain and spinal cord of the cat. Brain Res. 1982 Jul 15; 243(2):391-4. Taylor JE, Yaksh TL, Richelson E. PMID: 7104749.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    623. Origin and distribution of cholecystokinin-containing nerve terminals in the lumbar dorsal horn and nucleus caudalis of the cat. Brain Res. 1982 Jul 15; 243(2):363-8. Maderdrut JL, Yaksh TL, Petrusz P, Go VL. PMID: 6179576.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    624. Studies on the location and release of cholecystokinin and vasoactive intestinal peptide in rat and cat spinal cord. Brain Res. 1982 Jun 24; 242(2):279-90. Yaksh TL, Abay EO, Go VL. PMID: 6896838.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    625. Studies on the intrathecal effect of beta-endorphin in primate. Brain Res. 1982 Jun 10; 241(2):261-9. Yaksh TL, Gross KE, Li CH. PMID: 6286042.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    626. Peripheral and central substrates involved in the rostrad transmission of nociceptive information. Pain. 1982 May; 13(1):1-85. Yaksh TL, Hammond DL. PMID: 6287384.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    627. Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin. Eur J Pharmacol. 1982 Apr 23; 79(3-4):293-300. Yaksh TL, Harty GJ. PMID: 7047177.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    628. The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia. Pain. 1982 Apr; 12(4):343-356. Tung AS, Yaksh TL. PMID: 7099701.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    629. Opiate receptors and their definition by antagonists. Anesthesiology. 1982 Apr; 56(4):246-9. Yaksh TL, Howe JR. PMID: 6278990.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    630. Changes in sensitivity to intrathecal norepinephrine and serotonin after 6-hydroxydopamine (6-OHDA), 5,6-dihydroxytryptamine (5,6-DHT) or repeated monoamine administration. J Pharmacol Exp Ther. 1982 Feb; 220(2):311-21. Howe JR, Yaksh TL. PMID: 6120226.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    631. Pharmacological studies on the application, disposition, and release of neurotensin in the spinal cord. Ann N Y Acad Sci. 1982; 400:228-43. Yaksh TL, Schmauss C, Micevych PE, Abay EO, Go VL. PMID: 6188399.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    632. Spinal opiate analgesia: characteristics and principles of action. Pain. 1981 Dec; 11(3):293-346. Yaksh TL. PMID: 6276842.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    633. Functional aspects of bulbospinal monoaminergic projections in modulating processing of somatosensory information. Fed Proc. 1981 Nov; 40(13):2786-94. Yaksh TL, Hammond DL, Tyce GM. PMID: 6975220.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    634. Factors governing release of methionine enkephalin-like immunoreactivity from mesencephalon and spinal cord of the cat in vivo. J Neurophysiol. 1981 Nov; 46(5):1056-75. Yaksh TL, Elde RP. PMID: 7299446.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    635. Presence of conjugated 5-hydroxytryptamine in in vivo superfusates of rat spinal cord. J Neurochem. 1981 Oct; 37(4):1068-71. Hammond DL, Yaksh TL, Tyce GM. PMID: 6172561.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    636. An improved method for chronic catheterization of the rat spinal subarachnoid space. Physiol Behav. 1981 Sep; 27(3):559-61. LoPachin RM, Rudy TA, Yaksh TL. PMID: 7335798.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    637. Continuous low-dose intrathecal morphine administration in the treatment of chronic pain of malignant origin. Mayo Clin Proc. 1981 Aug; 56(8):516-20. Onofrio BM, Yaksh TL, Arnold PG. PMID: 6894954.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    638. The antinociceptive effects of intrathecally administered levonantradol and desacetyllevonantradol in the rat. J Clin Pharmacol. 1981 Aug-Sep; 21(S1):334S-340S. Yaksh TL. PMID: 6895380.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    639. Antagonism by phenoxybenzamine and pentazocine of the antinociceptive effects of morphine in the spinal cord. Neuropharmacology. 1981 Jun; 20(6):575-9. Russell B, Yaksh TL. PMID: 6894633.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    640. Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen. Anesthesiology. 1981 Jun; 54(6):451-67. Yaksh TL, Reddy SV. PMID: 6112935.
      View in: PubMed   Mentions: 60     Fields:    Translation:Animals
    641. Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system. J Physiol. 1981 May; 314:513-29. Tyce GM, Yaksh TL. PMID: 7310700; PMCID: PMC1249448.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    642. Release of norepinephrine and serotonin in cat spinal cord: direct in vivo evidence for the activation of descending monoamine pathways by somatic stimulation. J Physiol (Paris). 1981; 77(2-3):483-7. Yaksh TL, Tyce GM. PMID: 7288659.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    643. Peripheral and central pathways in pain. Pharmacol Ther. 1981; 14(3):459-75. Hammond DL, Yaksh TL. PMID: 7323138.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    644. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature. 1980 Jul 10; 286(5769):155-7. Yaksh TL, Jessell TM, Gamse R, Mudge AW, Leeman SE. PMID: 6157098.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    645. Resting and K+-evoked release of serotonin and norephinephrine in vivo from the rat and cat spinal cord. Brain Res. 1980 Jun 16; 192(1):133-46. Yaksh TL, Tyce GM. PMID: 7378777.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    646. Spinal cord pharmacology of adrenergic agonist-mediated antinociception. J Pharmacol Exp Ther. 1980 Jun; 213(3):525-33. Reddy SV, Maderdrut JL, Yaksh TL. PMID: 6110767.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    647. Release of methionine-enkephalin immunoreactivity from the rat spinal cord in vivo. Eur J Pharmacol. 1980 May 16; 63(4):359-62. Yaksh TL, Elde RP. PMID: 7389818.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    648. Spinal noradrenergic terminal system mediates antinociception. Brain Res. 1980 May 12; 189(2):391-401. Reddy SV, Yaksh TL. PMID: 6245762.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    649. Antinociceptive effects of lanthanum neodymium and europium following intrathecal administration. Neuropharmacology. 1980 Feb; 19(2):181-5. Reddy SV, Yaksh TL. PMID: 6892653.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    650. Analgesia produced by a spinal action of morphine and effects upon parturition in the rat. Anesthesiology. 1979 Nov; 51(5):386-92. Yaksh TL, Wilson PR, Kaiko RF, Inturrisi CE. PMID: 582883.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    651. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science. 1979 Oct 26; 206(4417):481-3. Yaksh TL, Farb DH, Leeman SE, Jessell TM. PMID: 228392.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    652. Microinjection of morphine into the periaqueductal gray evokes the release of serotonin from spinal cord. Brain Res. 1979 Jul 27; 171(1):176-81. Yaksh TL, Tyce GM. PMID: 466437.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    653. Spinal serotonin terminal system mediates antinociception. J Pharmacol Exp Ther. 1979 Mar; 208(3):446-53. Yaksh TL, Wilson PR. PMID: 581884.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    654. Responses of single units in laminae 2 and 3 of cat spinal cord. Brain Res. 1979 Jan 12; 160(2):245-60. Wall PD, Merrill EG, Yaksh TL. PMID: 216459.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    655. Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray. Brain Res. 1979 Jan 05; 160(1):180-5. Yaksh TL. PMID: 581478.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    656. Properties of two unmyelinated fibre tracts of the central nervous system: lateral Lissauer tract, and parallel fibres of the cerebellum. J Physiol. 1978 Nov; 284:127-45. Merrill EG, Wall PD, Yaksh TL. PMID: 731475; PMCID: PMC1282812.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    657. Baclofen is antinociceptive in the spinal intrathecal space of animals. Eur J Pharmacol. 1978 Oct 15; 51(4):323-30. Wilson PR, Yaksh TL. PMID: 581376.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    658. Antinociceptive effects of intrathecally administered human beta-endorphin in the rat and cat. Can J Physiol Pharmacol. 1978 Oct; 56(5):754-9. Yaksh TL, Henry JL. PMID: 581358.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    659. Analgetic actions of intrathecal opiates in cat and primate. Brain Res. 1978 Sep 15; 153(1):205-10. Yaksh TL. PMID: 98219.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    660. Effect of Lissauer tract stimulation on activity in dorsal roots and in ventral roots. Exp Neurol. 1978 Jul; 60(3):570-83. Wall PD, Yaksh TL. PMID: 680058.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    661. Effect on the nociceptive threshold and EEG activity in the rat of morphine injected into the medial thalamus and the periaqueductal gray. Neuropharmacology. 1978 Jul; 17(7):525-32. Yeung JC, Yaksh TL, Rudy TA. PMID: 692816.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    662. In vivo comparison of the receptor populations acted upon in the spinal cord by morphine and pentapeptides in the production of analgesia. Brain Res. 1978 Jun 16; 148(2):516-20. Yaksh TL, Frederickson RC, Huang SP, Rudy TA. PMID: 207391.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    663. Inhibition by etorphine of the discharge of dorsal horn neurons: effects on the neuronal response to both high- and low-threshold sensory input in the decerebrate spinal cat. Exp Neurol. 1978 May 15; 60(1):23-40. Yaksh TL. PMID: 658193.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    664. Narcotic analgestics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques. Pain. 1978 Apr; 4(4):299-359. Yaksh TL, Rudy TA. PMID: 25403.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    665. Opiate receptors for behavioral analgesia resemble those related to the depression of spinal nociceptive neurons. Science. 1978 Mar 17; 199(4334):1231-3. Yaksh TL. PMID: 204008.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    666. Hyperthermia produced by simulated intraventricular hemorrhage in the cat. Exp Neurol. 1978 Jan 15; 58(2):296-310. Rudy TA, Westergaard JL, Yaksh TL. PMID: 618748.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    667. A dose ratio comparison of the interaction between morphine and cyclazocine with naloxone in rhesus monkeys on the shock titration task. Eur J Pharmacol. 1977 Nov 15; 46(2):83-92. Yaksh TL, Rudy TA. PMID: 412680.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    668. Antagonism by indomethacin of neurogenic hyperthermia produced by unilateral puncture of the anterior hypothalamic/preoptic region. J Physiol. 1977 Nov; 272(3):721-36. Rudy TA, Williams JW, Yaksh TL. PMID: 592211; PMCID: PMC1353651.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    669. Concurrent mapping of brain sites for sensitivity to the direct application of morphine and focal electrical stimulation in the production of antinociception in the rat. Pain. 1977 Oct; 4(1):23-40. Yeung JC, Yaksh TL, Rudy TA. PMID: 927879.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    670. Hyperthermic effects of morphine: set point manipulation by a direct spinal action. Br J Pharmacol. 1977 Sep; 61(1):91-6. Rudy TA, Yaksh TL. PMID: 912212; PMCID: PMC1667677.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    671. Studies on the direct spinal action of narcotics in the production of analgesia in the rat. J Pharmacol Exp Ther. 1977 Aug; 202(2):411-28. Yaksh TL, Rudy TA. PMID: 18600.
      View in: PubMed   Mentions: 60     Fields:    Translation:Animals
    672. Hyperthermic effects of morphine in the rat spinal cord [proceedings]. J Physiol. 1977 Jun; 268(1):10P-11P. Rudy TA, Yaksh TL. PMID: 874880.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    673. Induction of tolerance and withdrawal in rats receiving morphine in the spinal subarachnoid space. Eur J Pharmacol. 1977 Apr 07; 42(3):275-84. Yaksh TL, Kohl RL, Rudy TA. PMID: 15848.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    674. Depression by morphine of the resting and evoked release of [3H]-acetylcholine from the cat caudate nucleus in vivo. Neuropharmacology. 1977 Apr; 16(4):227-33. Yaksh TL, Yamamura HI. PMID: 859683.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    675. Studies on the antagonism by raphe lesions of the antinociceptive action of systemic morphine. Eur J Pharmacol. 1977 Feb 21; 41(4):399-408. Yaksh TL, Plant RL, Rudy TA. PMID: 14836.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    676. Medial thalamic lesions in the rat: effects on the nociceptive threshold and morphine antinociception. Neuropharmacology. 1977 Feb; 16(2):107-14. Yaksh TL, Yeung JC, Rudy TA. PMID: 840367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    677. An extensive exploration of the rat brain for sites mediating prostaglandin-induced hyperthermia. Brain Res. 1977 Jan 21; 120(2):251-62. Williams JW, Rudy TA, Yaksh TL, Viswanathan CT. PMID: 832123.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    678. The direct and specific opiate-like effect of met5-enkephalin and analogues on the spinal cord. Neuroscience. 1977; 2(4):593-6. Yaksh TL, Huang SP, Rudy TA. PMID: 917285.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    679. Chronic catheterization of the spinal subarachnoid space. Physiol Behav. 1976 Dec; 17(6):1031-6. Yaksh TL, Rudy TA. PMID: 14677603.
      View in: PubMed   Mentions: 452     Fields:    Translation:Animals
    680. Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effects within the periaqueductal gray. Brain Res. 1976 Sep 10; 114(1):83-103. Yaksh TL, Yeung JC, Rudy TA. PMID: 963546.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    681. Analgesia mediated by a direct spinal action of narcotics. Science. 1976 Jun 25; 192(4246):1357-8. Yaksh TL, Rudy TA. PMID: 1273597.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    682. An inability to antagonize with naloxone the elevated nociceptive thresholds resulting from electrical stimulation of the mesencephalic central gray. Life Sci. 1976 Jun 01; 18(11):1193-8. Yaksh TL, Yeung JC, Rudy TA. PMID: 933708.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    683. Antagonism by methysergide and cinanserin of the antinociceptive action of morphine administered into the periaqueductal gray. Brain Res. 1976 Mar 12; 104(2):367-72. Yaksh TL, DuChateau JC, Rudy TA. PMID: 1260435.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    684. Acetylcholinesterase turnover in brain, cerebrospinal fluid and plasma. J Neurochem. 1975 Dec; 25(6):853-60. Yaksh TL, Filbert MG, Harris LW, Yamamura HI. PMID: 1206402.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    685. Effects of brain lesions on the antinociceptive properties of morphine in rats. Clin Exp Pharmacol Physiol. 1975 May-Jun; 2(3):261-8. Yeung JC, Yaksh TL, Rudy TA. PMID: 1149330.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    686. Blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat. Brain Res. 1975 Jan 17; 83(3):520-4. Yaksh TL, Yamamura HI. PMID: 1111819.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    687. Localization of the antinociceptive action of morphine in primate brain. Pharmacol Biochem Behav. 1975 Jan-Feb; 3(1):133-8. Pert A, Yaksh T. PMID: 1129350.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    688. Sites of morphine induced analgesia in the primate brain: relation to pain pathways. Brain Res. 1974 Nov 08; 80(1):135-40. Pert A, Yaksh T. PMID: 4424093.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    689. Fever produced by endotoxin injected into the hypothalamus of the monkey and its antagonism by salicylate. J Physiol. 1974 Nov; 243(1):167-93. Myers RD, Rudy TA, Yaksh TL. PMID: 4615138; PMCID: PMC1330695.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    690. Evocation of a biphasic febrile response in the rhesus monkey by intracerebral injection of bacterial endotoxins. Neuropharmacology. 1973 Dec; 12(12):1195-8. Myers RD, Rudy TA, Yaksh TL. PMID: 4205774.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    691. Effects of repeated withdrawal of cerebrospinal fluid by cisternal puncture on cisternal protein levels in the unanesthetized cat. Physiol Behav. 1973 Jan; 10(1):149-51. Yaksh TL, Fedele LA, Yamamura HI. PMID: 4697008.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    692. Ethanol preference in the rat: interactions between brain serotonin and ethanol, acetaldehyde, paraldehyde, 5-HTP and 5-HTOL. Neuropharmacology. 1972 Jul; 11(4):539-49. Myers RD, Evans JE, Yaksh TL. PMID: 4261739.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    693. Hypothalamic "coding" in the unanesthetized monkey of noradrenergic sites mediating feeding and thermoregulation. Physiol Behav. 1972 Feb; 8(2):251-7. Yaksh TL, Myers RD. PMID: 4198736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    694. Effect in the rhesus monkey of salicylate on centrally-induced endotoxin fevers. Neuropharmacology. 1971 Nov; 10(6):775-8. Myers RD, Rudy TA, Yaksh TL. PMID: 5001836.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    695. Fever in the monkey produced by the direct action of pyrogen on the hypothalamus. Experientia. 1971 Feb 15; 27(2):160-1. Myers RD, Rudy TA, Yaksh TL. PMID: 5544727.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
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