David Cheresh

Title(s)Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Exploiting KRAS addiction for lung cancer therapy
    NIH/NCI R01CA212411Sep 19, 2018 - Aug 31, 2023
    Role: Principal Investigator
    Attacking stress tolerance in cancer
    NIH/NCI R35CA220512Sep 18, 2018 - Aug 31, 2025
    Role: Principal Investigator
    Targeting a non-canonical RAS-driven pathway in pancreatic cancer
    NIH/NCI R01CA168692Jul 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    MicroRNA regulation of RasGAP's during angiogenesis
    NIH/NHLBI R01HL103956Jun 15, 2011 - May 31, 2016
    Role: Principal Investigator
    Identification of novel pancreatic cancer biomarkers
    NIH/NCI R21CA129660Sep 1, 2007 - Aug 31, 2009
    Role: Principal Investigator
    Endothelial Barrier Function Regulation by VEGF
    NIH/NHLBI R01HL078912Aug 1, 2005 - Jul 31, 2010
    Role: Principal Investigator
    Targeting Vessels in Tumors
    NIH P01CA104898May 16, 2005 - Aug 31, 2011
    Role: Co-Investigator
    Biological Response to the Extracellular Matrix
    NIH/NCI R13CA094245Apr 1, 2002 - Dec 31, 2002
    Role: Principal Investigator
    Regulation of cell invasion by apoptotic mechanisms
    NIH/NCI R01CA095262Mar 1, 2002 - May 31, 2012
    Role: Principal Investigator
    Angiogenesis and Mircrocirculation Conference
    NIH/NCI R13CA092869Jun 1, 2001 - May 31, 2002
    Role: Principal Investigator
    NIH/NHLBI R13HL065737Aug 1, 2000 - Jul 31, 2001
    Role: Principal Investigator
    Combinatorial Chemistry and Cancer Target
    NIH P01CA078045May 7, 1998 - Feb 28, 2010
    Role: Co-Investigator
    Integrin Signaling in Hemostasis and Blood Diseases
    NIH/NHLBI P01HL057900Apr 1, 1997 - Mar 31, 2007
    Role: Co-Investigator
    NIH/NHLBI R01HL054444Jun 1, 1995 - May 31, 1999
    Role: Principal Investigator
    VEGF and PDGF in angiogenesis and tumor progression
    NIH/NCI R37CA050286Aug 1, 1989 - Apr 30, 2014
    Role: Principal Investigator
    CRAF-mediated vascular resistance to cancer therapies
    NIH/NCI R01CA050286Aug 1, 1989 - May 31, 1994
    Role: Principal Investigator
    Integrin alpha v beta 3 promotes resistance to EGF receptor inhibitors
    NIH/NCI R01CA045726Apr 1, 1988 - May 31, 2012
    Role: Principal Investigator
    NIH/NCI F32CA007544Mar 1, 1985
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin avß5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038.
      View in: PubMed   Mentions: 5     Fields:    
    2. Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression. Cancer Res. 2019 10 01; 79(19):5048-5059. Wettersten HI, Weis SM, Pathria P, Von Schalscha T, Minami T, Varner JA, Cheresh DA. PMID: 31416839.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. Nat Cell Biol. 2019 02; 21(2):238-250. Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM. PMID: 30664790.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    4. Integrin CD11b activation drives anti-tumor innate immunity. Nat Commun. 2018 12 19; 9(1):5379. Schmid MC, Khan SQ, Kaneda MM, Pathria P, Shepard R, Louis TL, Anand S, Woo G, Leem C, Faridi MH, Geraghty T, Rajagopalan A, Gupta S, Ahmed M, Vazquez-Padron RI, Cheresh DA, Gupta V, Varner JA. PMID: 30568188.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    5. Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell Discov. 2018; 4:26. Wang H, Lapek J, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Melo CM, Miller YI, Elliott KC, Cheresh DA, Klemke RL. PMID: 29872538.
      View in: PubMed   Mentions:
    6. Re-thinking the preclinical development of GBM therapeutics. Oncoscience. 2018 Jan; 5(1-2):11-12. Cosset É, Weis SM, Cheresh DA. PMID: 29556513.
      View in: PubMed   Mentions:
    7. Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. J Clin Invest. 2018 01 02; 128(1):531-544. Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. PMID: 29227280.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    8. Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma. Cancer Cell. 2017 Dec 11; 32(6):856-868.e5. Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, Guan KL, Dietrich PY, Weis SM, Mischel PS, Cheresh DA. PMID: 29198914.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    9. Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discov. 2017 12; 7(12):1464-1479. Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. PMID: 28893801.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    10. Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke's encephalopathy. Neurosci Lett. 2017 03 06; 642:163-167. Hazell AS, Afadlal S, Cheresh DA, Azar A. PMID: 28109775.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    11. MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment. Nat Commun. 2016 11 25; 7:13597. Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S. PMID: 27886180.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. Kinase-independent role for CRAF-driving tumour radioresistance via CHK2. Nat Commun. 2015 Sep 03; 6:8154. Advani SJ, Camargo MF, Seguin L, Mielgo A, Anand S, Hicks AM, Aguilera J, Franovic A, Weis SM, Cheresh DA. PMID: 26333361.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    13. Glioblastomas require integrin avß3/PAK4 signaling to escape senescence. Cancer Res. 2015 Nov 01; 75(21):4466-73. Franovic A, Elliott KC, Seguin L, Camargo MF, Weis SM, Cheresh DA. PMID: 26297735.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    14. hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature. Stem Cell Reports. 2015 Jun 09; 4(6):1075-88. Acevedo LM, Lindquist JN, Walsh BM, Sia P, Cimadamore F, Chen C, Denzel M, Pernia CD, Ranscht B, Terskikh A, Snyder EY, Cheresh DA. PMID: 26004631.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    15. Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends Cell Biol. 2015 Apr; 25(4):234-40. Seguin L, Desgrosellier JS, Weis SM, Cheresh DA. PMID: 25572304.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansCells
    16. Integrin avß3 drives slug activation and stemness in the pregnant and neoplastic mammary gland. Dev Cell. 2014 Aug 11; 30(3):295-308. Desgrosellier JS, Lesperance J, Seguin L, Gozo M, Kato S, Franovic A, Yebra M, Shattil SJ, Cheresh DA. PMID: 25117682.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    17. Targeting the Achilles' heel of drug-resistant cancer stem cells. . 2014; 13(13):2017-8. Seguin L, Gozo M, Weis SM, Cheresh DA. PMID: 24906000.
      View in: PubMed   Mentions:
    18. Variety in the tumor microenvironment: integrin splicing regulates stemness. Cell Stem Cell. 2014 May 01; 14(5):557-8. Seguin L, Weis SM, Cheresh DA. PMID: 24792112.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. An integrin ß3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68. Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. PMID: 24747441.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    20. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. J Cell Biol. 2014 Jan 20; 204(2):247-63. Jean C, Chen XL, Nam JO, Tancioni I, Uryu S, Lawson C, Ward KK, Walsh CT, Miller NL, Ghassemian M, Turowski P, Dejana E, Weis S, Cheresh DA, Schlaepfer DD. PMID: 24446483.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    21. Tumor angiogenesis: putting a value on plastic GEMMs. Circ Res. 2014 Jan 03; 114(1):9-11. Cheresh DA, Stupack DG. PMID: 24385501.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    22. Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. J Clin Invest. 2013 Nov; 123(11):4900-8. Westenskow PD, Kurihara T, Aguilar E, Scheppke EL, Moreno SK, Wittgrove C, Marchetti V, Michael IP, Anand S, Nagy A, Cheresh D, Friedlander M. PMID: 24084735.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    23. A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood. 2013 Dec 12; 122(25):4140-9. Han J, Zhang G, Welch EJ, Liang Y, Fu J, Vogel SM, Lowell CA, Du X, Cheresh DA, Malik AB, Li Z. PMID: 24108461.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    24. A wake-up call for hibernating tumour cells. Nat Cell Biol. 2013 Jul; 15(7):721-3. Weis SM, Cheresh DA. PMID: 23817234.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. PI3Ka activates integrin a4ß1 to establish a metastatic niche in lymph nodes. Proc Natl Acad Sci U S A. 2013 May 28; 110(22):9042-7. Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. PMID: 23671068.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    26. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 2012 Jul 10; 22(1):21-35. Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. PMID: 22789536.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansCells
    27. Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. J Cell Biol. 2012 Jun 25; 197(7):907-19. Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD. PMID: 22734001.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    28. EGFR-mediated carcinoma cell metastasis mediated by integrin avß5 depends on activation of c-Src and cleavage of MUC1. PLoS One. 2012; 7(5):e36753. Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. PMID: 22586492.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    29. The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome. Int J Cancer. 2012 Oct 15; 131(8):1744-54. Yu PT, Babicky M, Jaquish D, French R, Marayuma K, Mose E, Niessen S, Hoover H, Shields D, Cheresh D, Cravatt BF, Lowy AM. PMID: 22275185.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    30. VEGF-induced vascular permeability is mediated by FAK. Dev Cell. 2012 Jan 17; 22(1):146-57. Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD. PMID: 22264731.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    31. Emerging Role of Micro-RNAs in the Regulation of Angiogenesis. Genes Cancer. 2011 Dec; 2(12):1134-8. Anand S, Cheresh DA. PMID: 22866204.
      View in: PubMed   Mentions:
    32. Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood. 2012 Mar 01; 119(9):2149-58. Scheppke L, Murphy EA, Zarpellon A, Hofmann JJ, Merkulova A, Shields DJ, Weis SM, Byzova TV, Ruggeri ZM, Iruela-Arispe ML, Cheresh DA. PMID: 22134168.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    33. Monographs editor. Genes Cancer. 2011 Dec; 2(12):1071. Cheresh DA. PMID: 22866197.
      View in: PubMed   Mentions:
    34. Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies. Genes Cancer. 2011 Dec; 2(12):1159-65. Reardon DA, Cheresh D. PMID: 22866207.
      View in: PubMed   Mentions:
    35. A MEK-independent role for CRAF in mitosis and tumor progression. Nat Med. 2011 Nov 13; 17(12):1641-5. Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA. PMID: 22081024.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    36. Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med. 2011 Nov 07; 17(11):1359-70. Weis SM, Cheresh DA. PMID: 22064426.
      View in: PubMed   Mentions: 480     Fields:    Translation:HumansCells
    37. EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 2012 May 31; 31(22):2783-93. Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. PMID: 21963850.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    38. aV integrins in angiogenesis and cancer. Cold Spring Harb Perspect Med. 2011 Sep; 1(1):a006478. Weis SM, Cheresh DA. PMID: 22229119.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    39. Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia. Nat Med. 2011 Jun 19; 17(7):845-53. Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M. PMID: 21685897.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    40. Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression. Cancer Cell. 2011 Jun 14; 19(6):715-27. Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA. PMID: 21665146.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimals
    41. A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels. Liver Int. 2011 Sep; 31(8):1222-30. Aspinall RJ, Weis SM, Barnes L, Lutu-Fuga K, Bylund DJ, Pockros PJ, Cheresh DA. PMID: 21745297.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    42. MicroRNA-mediated regulation of the angiogenic switch. Curr Opin Hematol. 2011 May; 18(3):171-6. Anand S, Cheresh DA. PMID: 21423013.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    43. Targeted nanogels: a versatile platform for drug delivery to tumors. . 2011 Jun; 10(6):972-82. Murphy EA, Majeti BK, Mukthavaram R, Acevedo LM, Barnes LA, Cheresh DA. PMID: 21518727.
      View in: PubMed   Mentions:
    44. Oncogenic Ras/Src cooperativity in pancreatic neoplasia. Oncogene. 2011 May 05; 30(18):2123-34. Shields DJ, Murphy EA, Desgrosellier JS, Mielgo A, Lau SK, Barnes LA, Lesperance J, Huang M, Schmedt C, Tarin D, Lowy AM, Cheresh DA. PMID: 21242978.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    45. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 2010 Aug; 16(8):909-14. Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA. PMID: 20676106.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansAnimalsCells
    46. Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Cancer Res. 2010 Apr 15; 70(8):3042-51. Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. PMID: 20388801.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    47. Derivation of vasculature from embryonic stem cells. Curr Protoc Stem Cell Biol. 2010 Mar; Chapter 1:Unit 1F.9. Lindquist JN, Cheresh DA, Snyder EY. PMID: 20200855.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    48. Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4299-304. Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA. PMID: 20154271.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    49. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2010 Jan; 10(1):9-22. Desgrosellier JS, Cheresh DA. PMID: 20029421.
      View in: PubMed   Mentions: 1029     Fields:    Translation:HumansAnimalsCells
    50. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2189-94. Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. PMID: 20080647.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    51. VEGF as an inhibitor of tumor vessel maturation: implications for cancer therapy. Expert Opin Biol Ther. 2009 Nov; 9(11):1347-56. Greenberg JI, Cheresh DA. PMID: 19761418.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    52. An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat Med. 2009 Oct; 15(10):1163-9. Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prévost N, Tarin D, Shattil SJ, Cheresh DA. PMID: 19734908.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    53. Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation. J Cell Sci. 2009 Jun 01; 122(Pt 11):1812-22. Koh W, Sachidanandam K, Stratman AN, Sacharidou A, Mayo AM, Murphy EA, Cheresh DA, Davis GE. PMID: 19435802.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    54. Agonizing integrin antagonists? Cancer Cell. 2009 May 05; 15(5):359-61. Weis SM, Stupack DG, Cheresh DA. PMID: 19411065.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    55. Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue. J Biomed Opt. 2009 Mar-Apr; 14(2):024032. Makale M, McElroy M, O'Brien P, Hoffman RM, Guo S, Bouvet M, Barnes L, Ingulli E, Cheresh D. PMID: 19405761.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    56. Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. Cancer Res. 2009 Feb 15; 69(4):1383-91. Ricono JM, Huang M, Barnes LA, Lau SK, Weis SM, Schlaepfer DD, Hanks SK, Cheresh DA. PMID: 19208836.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    57. Suppressing NFAT increases VEGF signaling in hemangiomas. Cancer Cell. 2008 Dec 09; 14(6):429-30. Acevedo LM, Cheresh DA. PMID: 19061833.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    58. Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease. J Pharmacol Exp Ther. 2009 Mar; 328(3):758-65. Doukas J, Eide L, Stebbins K, Racanelli-Layton A, Dellamary L, Martin M, Dneprovskaia E, Noronha G, Soll R, Wrasidlo W, Acevedo LM, Cheresh DA. PMID: 19056934.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    59. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature. 2008 Dec 11; 456(7223):809-13. Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, Huang J, Scheppke L, Stockmann C, Johnson RS, Angle N, Cheresh DA. PMID: 18997771.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansAnimalsCells
    60. Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature. 2008 Dec 11; 456(7223):814-8. Stockmann C, Doedens A, Weidemann A, Zhang N, Takeda N, Greenberg JI, Cheresh DA, Johnson RS. PMID: 18997773.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    61. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene. 2008 Oct 20; 27(48):6285-98. Cheresh DA, Stupack DG. PMID: 18931694.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    62. Matrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: a computational time-lapse study. Mol Biol Cell. 2008 Dec; 19(12):5529-40. Rupp PA, Visconti RP, Czirók A, Cheresh DA, Little CD. PMID: 18923152.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    63. Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc Natl Acad Sci U S A. 2008 Jul 08; 105(27):9343-8. Murphy EA, Majeti BK, Barnes LA, Makale M, Weis SM, Lutu-Fuga K, Wrasidlo W, Cheresh DA. PMID: 18607000.
      View in: PubMed   Mentions: 120     Fields:    Translation:AnimalsCells
    64. Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits. J Clin Invest. 2008 Jun; 118(6):2337-46. Scheppke L, Aguilar E, Gariano RF, Jacobson R, Hood J, Doukas J, Cao J, Noronha G, Yee S, Weis S, Martin MB, Soll R, Cheresh DA, Friedlander M. PMID: 18483622.
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    65. H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors. Circ Res. 2008 Jun 06; 102(11):1350-8. Serban D, Leng J, Cheresh D. PMID: 18467631.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    66. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. J Cell Biol. 2008 Apr 07; 181(1):43-50. Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA. PMID: 18391070.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    67. Robo4 counteracts VEGF signaling. Nat Med. 2008 Apr; 14(4):372-3. Acevedo LM, Weis SM, Cheresh DA. PMID: 18391935.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    68. Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood. 2008 Mar 01; 111(5):2674-80. Acevedo LM, Barillas S, Weis SM, Göthert JR, Cheresh DA. PMID: 18180379.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    69. Preface: a tribute to Dr. Judah Folkman. Methods Enzymol. 2008; 443:xv-xvi. Cheresh DA. PMID: 18772007.
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    70. Gain-of-function mutational activation of human tRNA synthetase procytokine. Chem Biol. 2007 Dec; 14(12):1323-33. Yang XL, Kapoor M, Otero FJ, Slike BM, Tsuruta H, Frausto R, Bates A, Ewalt KL, Cheresh DA, Schimmel P. PMID: 18096501.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    71. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature. 2007 Apr 05; 446(7136):690-4. Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA, Karin M. PMID: 17377533.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansAnimalsCells
    72. Chemoresistance of endothelial cells induced by basic fibroblast growth factor depends on Raf-1-mediated inhibition of the proapoptotic kinase, ASK1. Cancer Res. 2007 Mar 15; 67(6):2766-72. Alavi AS, Acevedo L, Min W, Cheresh DA. PMID: 17363598.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    73. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19866-71. Doukas J, Wrasidlo W, Noronha G, Dneprovskaia E, Fine R, Weis S, Hood J, Demaria A, Soll R, Cheresh D. PMID: 17172449.
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    74. Cooperation between VEGF and beta3 integrin during cardiac vascular development. Blood. 2007 Mar 01; 109(5):1962-70. Weis SM, Lindquist JN, Barnes LA, Lutu-Fuga KM, Cui J, Wood MR, Cheresh DA. PMID: 17062734.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    75. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 2006 Sep 28; 25(44):5969-84. Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. PMID: 16682956.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    76. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature. 2006 Jan 05; 439(7072):95-9. Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA. PMID: 16397500.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    77. Pathophysiological consequences of VEGF-induced vascular permeability. Nature. 2005 Sep 22; 437(7058):497-504. Weis SM, Cheresh DA. PMID: 16177780.
      View in: PubMed   Mentions: 248     Fields:    Translation:HumansAnimalsCells
    78. Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state. J Biol Chem. 2005 Sep 09; 280(36):31906-12. Potter MD, Barbero S, Cheresh DA. PMID: 16027153.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansAnimalsCells
    79. Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. J Cell Biol. 2004 Oct 25; 167(2):223-9. Weis S, Cui J, Barnes L, Cheresh D. PMID: 15504909.
      View in: PubMed   Mentions: 169     Fields:    Translation:AnimalsCells
    80. A Bit-role for integrins in apoptosis. Nat Cell Biol. 2004 May; 6(5):388-9. Stupack DG, Cheresh DA. PMID: 15122265.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    81. Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. J Clin Invest. 2004 Mar; 113(6):885-94. Weis S, Shintani S, Weber A, Kirchmair R, Wood M, Cravens A, McSharry H, Iwakura A, Yoon YS, Himes N, Burstein D, Doukas J, Soll R, Losordo D, Cheresh D. PMID: 15067321.
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    82. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. J Immunother. 2004 Mar-Apr; 27(2):161-75. McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. PMID: 14770088.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    83. Integrins and angiogenesis. Curr Top Dev Biol. 2004; 64:207-38. Stupack DG, Cheresh DA. PMID: 15563949.
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    84. Apoptotic cues from the extracellular matrix: regulators of angiogenesis. Oncogene. 2003 Dec 08; 22(56):9022-9. Stupack DG, Cheresh DA. PMID: 14663480.
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    85. Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol. 2003 Sep 01; 162(5):933-43. Hood JD, Frausto R, Kiosses WB, Schwartz MA, Cheresh DA. PMID: 12952943.
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    86. Building a better Trap. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8624-5. Hood JD, Cheresh DA. PMID: 12861079.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    87. Role of Raf in vascular protection from distinct apoptotic stimuli. Science. 2003 Jul 04; 301(5629):94-6. Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. PMID: 12843393.
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    88. Differential regulation of cell motility and invasion by FAK. J Cell Biol. 2003 Mar 03; 160(5):753-67. Hsia DA, Mitra SK, Hauck CR, Streblow DN, Nelson JA, Ilic D, Huang S, Li E, Nemerow GR, Leng J, Spencer KS, Cheresh DA, Schlaepfer DD. PMID: 12615911.
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    89. FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth. EMBO J. 2002 Dec 02; 21(23):6289-302. Hauck CR, Hsia DA, Puente XS, Cheresh DA, Schlaepfer DD. PMID: 12456636.
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    90. Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci. 2002 Oct 01; 115(Pt 19):3729-38. Stupack DG, Cheresh DA. PMID: 12235283.
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    91. Tumor regression by targeted gene delivery to the neovasculature. Science. 2002 Jun 28; 296(5577):2404-7. Hood JD, Bednarski M, Frausto R, Guccione S, Reisfeld RA, Xiang R, Cheresh DA. PMID: 12089446.
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    92. Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase. J Biol Chem. 2002 Jun 07; 277(23):20124-6. Wakasugi K, Slike BM, Hood J, Ewalt KL, Cheresh DA, Schimmel P. PMID: 11956181.
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    93. A dominant-negative p65 PAK peptide inhibits angiogenesis. Circ Res. 2002 Apr 05; 90(6):697-702. Kiosses WB, Hood J, Yang S, Gerritsen ME, Cheresh DA, Alderson N, Schwartz MA. PMID: 11934838.
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    94. Herpesvirus hijacks an integrin. Nat Cell Biol. 2002 Apr; 4(4):E69-71. Nemerow GR, Cheresh DA. PMID: 11944033.
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    95. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol. 2002 Apr 01; 157(1):149-60. Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. PMID: 11927607.
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    96. Integrin-mediated death: an explanation of the integrin-knockout phenotype? Nat Med. 2002 Mar; 8(3):193-4. Cheresh DA, Stupack DG. PMID: 11875466.
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    97. Loss of p53 compensates for alpha v-integrin function in retinal neovascularization. J Biol Chem. 2002 Apr 19; 277(16):13371-4. Strömblad S, Fotedar A, Brickner H, Theesfeld C, Aguilar de Diaz E, Friedlander M, Cheresh DA. PMID: 11856728.
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    98. ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands. Sci STKE. 2002 Feb 12; 2002(119):pe7. Stupack DG, Cheresh DA. PMID: 11842241.
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    99. Role of integrins in cell invasion and migration. Nat Rev Cancer. 2002 Feb; 2(2):91-100. Hood JD, Cheresh DA. PMID: 12635172.
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    100. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):178-83. Otani A, Slike BM, Dorrell MI, Hood J, Kinder K, Ewalt KL, Cheresh D, Schimmel P, Friedlander M. PMID: 11773625.
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    101. A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):173-7. Wakasugi K, Slike BM, Hood J, Otani A, Ewalt KL, Friedlander M, Cheresh DA, Schimmel P. PMID: 11773626.
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    102. Matrix metalloproteinase/integrin interactions as target for anti-angiogenic treatment strategies. Ann Hematol. 2002; 81 Suppl 2:S69-70. Kessler TA, Pfeifer A, Silletti S, Mesters RM, Berdel WE, Verma I, Cheresh D. PMID: 12611083.
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    103. Targeted delivery of mutant Raf kinase to neovessels causes tumor regression. Cold Spring Harb Symp Quant Biol. 2002; 67:285-91. Hood JD, Cheresh DA. PMID: 12858551.
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    104. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol. 2001 Oct 29; 155(3):459-70. Stupack DG, Puente XS, Boutsaboualoy S, Storgard CM, Cheresh DA. PMID: 11684710.
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    105. Adhesion events in angiogenesis. Curr Opin Cell Biol. 2001 Oct; 13(5):563-8. Eliceiri BP, Cheresh DA. PMID: 11544024.
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    106. Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. Neurosurgery. 2001 Aug; 49(2):380-9; discussion 390. Bello L, Francolini M, Marthyn P, Zhang J, Carroll RS, Nikas DC, Strasser JF, Villani R, Cheresh DA, Black PM. PMID: 11504114.
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    107. Integrin alpha(v)beta1 is an adenovirus coreceptor. J Virol. 2001 Jun; 75(11):5405-9. Li E, Brown SL, Stupack DG, Puente XS, Cheresh DA, Nemerow GR. PMID: 11333925.
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    108. Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging. Mol Ther. 2001 Mar; 3(3):319-22. Pfeifer A, Kessler T, Yang M, Baranov E, Kootstra N, Cheresh DA, Hoffman RM, Verma IM. PMID: 11273773.
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    109. Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3). J Am Chem Soc. 2001 Feb 21; 123(7):1280-8. Boger DL, Goldberg J, Silletti S, Kessler T, Cheresh DA. PMID: 11456699.
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    110. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke. Nat Med. 2001 Feb; 7(2):222-7. Paul R, Zhang ZG, Eliceiri BP, Jiang Q, Boccia AD, Zhang RL, Chopp M, Cheresh DA. PMID: 11175854.
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    111. Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. Proc Natl Acad Sci U S A. 2001 Jan 02; 98(1):119-24. Silletti S, Kessler T, Goldberg J, Boger DL, Cheresh DA. PMID: 11134507.
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    112. Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist. Neurosurgery. 2001 Jan; 48(1):151-7. MacDonald TJ, Taga T, Shimada H, Tabrizi P, Zlokovic BV, Cheresh DA, Laug WE. PMID: 11152340.
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    113. Alpha(v)beta3 and alpha(v)beta5 integrin expression in meningiomas. Neurosurgery. 2000 Nov; 47(5):1185-95. Bello L, Zhang J, Nikas DC, Strasser JF, Villani RM, Cheresh DA, Carroll RS, Black PM. PMID: 11063113.
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    114. Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):12227-32. Pfeifer A, Kessler T, Silletti S, Cheresh DA, Verma IM. PMID: 11035804.
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    115. Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3. Clin Cancer Res. 2000 Aug; 6(8):3056-61. Gutheil JC, Campbell TN, Pierce PR, Watkins JD, Huse WD, Bodkin DJ, Cheresh DA. PMID: 10955784.
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    116. Role of alpha v integrins during angiogenesis. Cancer J. 2000 May; 6 Suppl 3:S245-9. Eliceiri BP, Cheresh DA. PMID: 10874494.
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    117. Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of alpha(v) integrins. Oncogene. 2000 Apr 06; 19(15):1915-23. Huang S, Stupack D, Liu A, Cheresh D, Nemerow GR. PMID: 10773881.
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    118. Regulation of adenovirus membrane penetration by the cytoplasmic tail of integrin beta5. J Virol. 2000 Mar; 74(6):2731-9. Wang K, Guan T, Cheresh DA, Nemerow GR. PMID: 10684289.
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    119. beta1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway. Neuroscience. 2000; 101(4):1145-52. Bonfoco E, Chen W, Paul R, Cheresh DA, Cooper NR. PMID: 11113363.
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    120. Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase. J Biol Chem. 1999 Dec 31; 274(53):37855-61. Leng J, Klemke RL, Reddy AC, Cheresh DA. PMID: 10608850.
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    121. Bifurcation of cell migratory and proliferative signaling by the adaptor protein Shc. J Cell Biol. 1999 Dec 27; 147(7):1561-8. Collins LR, Ricketts WA, Yeh L, Cheresh D. PMID: 10613912.
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    122. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell. 1999 Dec; 4(6):915-24. Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. PMID: 10635317.
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    123. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. J Cell Biol. 1999 Sep 06; 146(5):1107-16. Cheresh DA, Leng J, Klemke RL. PMID: 10477763.
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    124. Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand. J Biol Chem. 1999 Jul 30; 274(31):21609-16. Pampori N, Hato T, Stupack DG, Aidoudi S, Cheresh DA, Nemerow GR, Shattil SJ. PMID: 10419468.
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    125. Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival. Cancer Res. 1999 Jun 01; 59(11):2724-30. Petitclerc E, Strömblad S, von Schalscha TL, Mitjans F, Piulats J, Montgomery AM, Cheresh DA, Brooks PC. PMID: 10363998.
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    126. The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest. 1999 May; 103(9):1227-30. Eliceiri BP, Cheresh DA. PMID: 10225964.
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    127. A role for angiogenesis in rheumatoid arthritis. Braz J Med Biol Res. 1999 May; 32(5):573-81. Stupack DG, Storgard CM, Cheresh DA. PMID: 10412569.
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    128. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase. J Cell Biol. 1999 Feb 22; 144(4):777-88. Stupack DG, Li E, Silletti SA, Kehler JA, Geahlen RL, Hahn K, Nemerow GR, Cheresh DA. PMID: 10037798.
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    129. Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1591-6. Lode HN, Moehler T, Xiang R, Jonczyk A, Gillies SD, Cheresh DA, Reisfeld RA. PMID: 9990069.
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    130. Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist. J Clin Invest. 1999 Jan; 103(1):47-54. Storgard CM, Stupack DG, Jonczyk A, Goodman SL, Fox RI, Cheresh DA. PMID: 9884333.
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    131. Use of the 10-day-old chick embryo model for studying angiogenesis. Methods Mol Biol. 1999; 129:257-69. Brooks PC, Montgomery AM, Cheresh DA. PMID: 10494570.
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    132. The role of alphav integrins during angiogenesis. Mol Med. 1998 Dec; 4(12):741-50. Eliceiri BP, Cheresh DA. PMID: 9990860.
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    133. Vascular integrin alpha(v)beta3: a new prognostic indicator in breast cancer. Clin Cancer Res. 1998 Nov; 4(11):2625-34. Gasparini G, Brooks PC, Biganzoli E, Vermeulen PB, Bonoldi E, Dirix LY, Ranieri G, Miceli R, Cheresh DA. PMID: 9829725.
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    134. Design, synthesis and biological evaluation of nonpeptide integrin antagonists. Bioorg Med Chem. 1998 Aug; 6(8):1185-208. Nicolaou KC, Trujillo JI, Jandeleit B, Chibale K, Rosenfeld M, Diefenbach B, Cheresh DA, Goodman SL. PMID: 9784861.
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    135. A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries. Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8910-5. Rader C, Cheresh DA, Barbas CF. PMID: 9671778.
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    136. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nat Med. 1998 May; 4(5):623-6. Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC. PMID: 9585240.
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    137. Death to a blood vessel, death to a tumor. Nat Med. 1998 Apr; 4(4):395-6. Cheresh DA. PMID: 9546782.
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    138. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol. 1998 Mar 09; 140(5):1255-63. Eliceiri BP, Klemke R, Strömblad S, Cheresh DA. PMID: 9490736.
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    139. Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase. J Virol. 1998 Mar; 72(3):2055-61. Li E, Stupack D, Klemke R, Cheresh DA, Nemerow GR. PMID: 9499060.
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    140. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol. 1998 Feb 23; 140(4):961-72. Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA. PMID: 9472046.
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    141. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell. 1998 Feb 06; 92(3):391-400. Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. PMID: 9476898.
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    142. Reduced intimal thickening following alpha(v)beta3 blockade is associated with smooth muscle cell apoptosis. Cell Adhes Commun. 1998; 6(5):371-9. van der Zee R, Murohara T, Passeri J, Kearney M, Cheresh DA, Isner JM. PMID: 10223353.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    143. A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins. J Cell Biol. 1997 Dec 15; 139(6):1567-81. Felding-Habermann B, Silletti S, Mei F, Siu CH, Yip PM, Brooks PC, Cheresh DA, O'Toole TE, Ginsberg MH, Montgomery AM. PMID: 9396761.
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    144. Induction of the angiogenic phenotype by Hox D3. J Cell Biol. 1997 Oct 06; 139(1):257-64. Boudreau N, Andrews C, Srebrow A, Ravanpay A, Cheresh DA. PMID: 9314544.
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    145. Regulation of cell motility by mitogen-activated protein kinase. J Cell Biol. 1997 Apr 21; 137(2):481-92. Klemke RL, Cai S, Giannini AL, Gallagher PJ, de Lanerolle P, Cheresh DA. PMID: 9128257.
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    146. Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo. J Clin Invest. 1997 Mar 15; 99(6):1390-8. Brooks PC, Klemke RL, Schon S, Lewis JM, Schwartz MA, Cheresh DA. PMID: 9077549.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    147. Cell adhesion and angiogenesis. Trends Cell Biol. 1996 Dec; 6(12):462-8. Strömblad S, Cheresh DA. PMID: 15157503.
      View in: PubMed   Mentions: 32     Fields:    
    148. Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration. J Biol Chem. 1996 Nov 15; 271(46):29393-9. Yebra M, Parry GC, Strömblad S, Mackman N, Rosenberg S, Mueller BM, Cheresh DA. PMID: 8910604.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    149. Integrins, angiogenesis and vascular cell survival. Chem Biol. 1996 Nov; 3(11):881-5. Strömblad S, Cheresh DA. PMID: 8939711.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    150. Integrins and cancer. Curr Opin Cell Biol. 1996 Oct; 8(5):724-30. Varner JA, Cheresh DA. PMID: 8939661.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    151. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9764-9. Friedlander M, Theesfeld CL, Sugita M, Fruttiger M, Thomas MA, Chang S, Cheresh DA. PMID: 8790405.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimals
    152. Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. J Cell Biol. 1996 Sep; 134(5):1323-32. Lewis JM, Cheresh DA, Schwartz MA. PMID: 8794871.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    153. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. J Clin Invest. 1996 Jul 15; 98(2):426-33. Strömblad S, Becker JC, Yebra M, Brooks PC, Cheresh DA. PMID: 8755653.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    154. Integrin alphavbeta3 is expressed in selected microvessels after focal cerebral ischemia. Am J Pathol. 1996 Jul; 149(1):37-44. Okada Y, Copeland BR, Hamann GF, Koziol JA, Cheresh DA, del Zoppo GJ. PMID: 8686760.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    155. Regulation of cell migration by the integrin beta subunit ectodomain. J Cell Sci. 1996 Jun; 109 ( Pt 6):1615-22. Filardo EJ, Deming SL, Cheresh DA. PMID: 8799848.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    156. Osteopontin activation of c-src in human melanoma cells requires the cytoplasmic domain of the integrin alpha v-subunit. Endocrinology. 1996 Jun; 137(6):2432-40. Chellaiah M, Fitzgerald C, Filardo EJ, Cheresh DA, Hruska KA. PMID: 8641196.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    157. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell. 1996 May 31; 85(5):683-93. Brooks PC, Strömblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, Cheresh DA. PMID: 8646777.
      View in: PubMed   Mentions: 353     Fields:    Translation:HumansAnimalsCells
    158. Transient functional expression of alphaVbeta 3 on vascular cells during wound repair. Am J Pathol. 1996 May; 148(5):1407-21. Clark RA, Tonnesen MG, Gailit J, Cheresh DA. PMID: 8623913.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    159. Cell-type specific recognition of RGD- and non-RGD-containing cell binding domains in fibrillin-1. J Biol Chem. 1996 Mar 01; 271(9):4916-22. Sakamoto H, Broekelmann T, Cheresh DA, Ramirez F, Rosenbloom J, Mecham RP. PMID: 8617764.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    160. Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3. J Cell Biol. 1996 Feb; 132(3):475-85. Montgomery AM, Becker JC, Siu CH, Lemmon VP, Cheresh DA, Pancook JD, Zhao X, Reisfeld RA. PMID: 8636223.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    161. Tumor angiogenesis and the role of vascular cell integrin alphavbeta3. Important Adv Oncol. 1996; 69-87. Varner JA, Cheresh DA. PMID: 8791129.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    162. Extracellular matrix and integrin composition of the normal bladder wall. World J Urol. 1996; 14 Suppl 1:S30-7. Wilson CB, Leopard J, Cheresh DA, Nakamura RM. PMID: 8738408.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    163. Definition of two angiogenic pathways by distinct alpha v integrins. Science. 1995 Dec 01; 270(5241):1500-2. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA. PMID: 7491498.
      View in: PubMed   Mentions: 270     Fields:    Translation:Animals
    164. REVIEW: the integrin alpha V beta 3: angiogenesis and apoptosis. Cell Adhes Commun. 1995 Nov; 3(4):367-74. Varner JA, Brooks PC, Cheresh DA. PMID: 8821037.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    165. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest. 1995 Oct; 96(4):1815-22. Brooks PC, Strömblad S, Klemke R, Visscher D, Sarkar FH, Cheresh DA. PMID: 7560073.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansAnimalsCells
    166. Selective type IV collagen defects in the urothelial basement membrane in interstitial cystitis. J Urol. 1995 Sep; 154(3):1222-6. Wilson CB, Leopard J, Nakamura RM, Cheresh DA, Stein PC, Parsons CL. PMID: 7637092.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    167. Induction of carcinoma cell migration on vitronectin by NF-kappa B-dependent gene expression. Mol Biol Cell. 1995 Jul; 6(7):841-50. Yebra M, Filardo EJ, Bayna EM, Kawahara E, Becker JC, Cheresh DA. PMID: 7579698.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    168. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. Endocrinology. 1995 Jul; 136(7):2984-92. Hruska KA, Rolnick F, Huskey M, Alvarez U, Cheresh D. PMID: 7540546.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    169. An antagonist of integrin alpha v beta 3 prevents maturation of blood vessels during embryonic neovascularization. J Cell Sci. 1995 Jul; 108 ( Pt 7):2655-61. Drake CJ, Cheresh DA, Little CD. PMID: 7593306.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimals
    170. Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. J Cell Biol. 1995 Jul; 130(2):441-50. Filardo EJ, Brooks PC, Deming SL, Damsky C, Cheresh DA. PMID: 7542248.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    171. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. Ann N Y Acad Sci. 1995 Apr 21; 760:151-65. Hruska KA, Rolnick F, Huskey M, Alvarez U, Cheresh D. PMID: 7540372.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    172. Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors. J Cell Sci. 1995 Mar; 108 ( Pt 3):947-56. Gladson CL, Wilcox JN, Sanders L, Gillespie GY, Cheresh DA. PMID: 7542670.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    173. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest. 1995 Feb; 95(2):713-24. Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. PMID: 7532190.
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    174. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell. 1994 Dec 30; 79(7):1157-64. Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA. PMID: 7528107.
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    175. Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. J Cell Biol. 1994 Nov; 127(3):859-66. Klemke RL, Yebra M, Bayna EM, Cheresh DA. PMID: 7525598.
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    176. Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization. J Cell Biol. 1994 Oct; 127(1):257-64. Wickham TJ, Filardo EJ, Cheresh DA, Nemerow GR. PMID: 7523420.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    177. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19):8856-60. Montgomery AM, Reisfeld RA, Cheresh DA. PMID: 7522323.
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    178. Specific roles of the alpha V beta 1, alpha V beta 3 and alpha V beta 5 integrins in avian neural crest cell adhesion and migration on vitronectin. Development. 1994 Sep; 120(9):2687-702. Delannet M, Martin F, Bossy B, Cheresh DA, Reichardt LF, Duband JL. PMID: 7525179.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    179. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 1994 Apr 22; 264(5158):569-71. Brooks PC, Clark RA, Cheresh DA. PMID: 7512751.
      View in: PubMed   Mentions: 715     Fields:    Translation:HumansAnimals
    180. A beta turn in the cytoplasmic tail of the integrin alpha v subunit influences conformation and ligand binding of alpha v beta 3. J Biol Chem. 1994 Feb 11; 269(6):4641-7. Filardo EJ, Cheresh DA. PMID: 7508446.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    181. Adenovirus entry into host cells: a role for alpha(v) integrins. Trends Cell Biol. 1994 Feb; 4(2):52-5. Nemerow GR, Cheresh DA, Wickham TJ. PMID: 14731867.
      View in: PubMed   Mentions: 12     Fields:    
    182. Anti-glycosphingolipid autoantibodies in rheumatologic disorders. J Clin Lab Anal. 1994; 8(6):378-84. Zeballos RS, Fox RI, Cheresh DA, McPherson RA. PMID: 7869176.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    183. A structural basis for bidirectional integrin signalling. Princess Takamatsu Symp. 1994; 24:106-17. Filardo EJ, Cheresh DA. PMID: 8983068.
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    184. Vitronectin and its receptors. Curr Opin Cell Biol. 1993 Oct; 5(5):864-8. Felding-Habermann B, Cheresh DA. PMID: 7694604.
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    185. Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption. J Biol Chem. 1993 May 05; 268(13):9901-7. Ross FP, Chappel J, Alvarez JI, Sander D, Butler WT, Farach-Carson MC, Mintz KA, Robey PG, Teitelbaum SL, Cheresh DA. PMID: 8486670.
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    186. Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell. 1993 Apr 23; 73(2):309-19. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR. PMID: 8477447.
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    187. Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J Cell Biol. 1993 Apr; 121(1):163-70. Leavesley DI, Schwartz MA, Rosenfeld M, Cheresh DA. PMID: 7681432.
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    188. Binding of osteopontin to the osteoclast integrin alpha v beta 3. Osteoporos Int. 1993; 3 Suppl 1:132-5. Miyauchi A, Alvarez J, Greenfield EM, Teti A, Grano M, Colucci S, Zambonin-Zallone A, Ross FP, Teitelbaum SL, Cheresh D. PMID: 8461540.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    189. Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin. J Clin Invest. 1992 Oct; 90(4):1406-13. Nip J, Shibata H, Loskutoff DJ, Cheresh DA, Brodt P. PMID: 1383272.
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    190. Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen. J Cell Biol. 1992 Jun; 117(5):1101-7. Leavesley DI, Ferguson GD, Wayner EA, Cheresh DA. PMID: 1374415.
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    191. Involvement of integrin alpha V gene expression in human melanoma tumorigenicity. J Clin Invest. 1992 Jun; 89(6):2018-22. Felding-Habermann B, Mueller BM, Romerdahl CA, Cheresh DA. PMID: 1376331.
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    192. Structural and biologic properties of integrin-mediated cell adhesion. Clin Lab Med. 1992 Jun; 12(2):217-36. Cheresh DA. PMID: 1611819.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    193. Distinct biological consequences of integrin alpha v beta 3-mediated melanoma cell adhesion to fibrinogen and its plasmic fragments. J Biol Chem. 1992 Mar 15; 267(8):5070-7. Felding-Habermann B, Ruggeri ZM, Cheresh DA. PMID: 1531979.
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    194. Role of alpha V integrins and vitronectin in human melanoma cell growth. Cold Spring Harb Symp Quant Biol. 1992; 57:233-40. Sanders LC, Felding-Habermann B, Mueller BM, Cheresh DA. PMID: 1285050.
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    195. Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. J Clin Invest. 1991 Dec; 88(6):1924-32. Gladson CL, Cheresh DA. PMID: 1721625.
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    196. Integrins in thrombosis, wound healing and cancer. Biochem Soc Trans. 1991 Nov; 19(4):835-8. Cheresh DA. PMID: 1794568.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    197. Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts. J Biol Chem. 1991 Oct 25; 266(30):20369-74. Miyauchi A, Alvarez J, Greenfield EM, Teti A, Grano M, Colucci S, Zambonin-Zallone A, Ross FP, Teitelbaum SL, Cheresh D. PMID: 1939092.
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    198. Arginine-glycine-aspartic acid binding leading to molecular stabilization between integrin alpha v beta 3 and its ligand. J Biol Chem. 1991 Oct 15; 266(29):19543-50. Orlando RA, Cheresh DA. PMID: 1717468.
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    199. Labeling of integrin alpha v beta 3 with 58Co(III). Evidence of metal ion coordination sphere involvement in ligand binding. J Biol Chem. 1991 Jun 25; 266(18):11429-32. Smith JW, Cheresh DA. PMID: 1711032.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    200. Structure, function and biological properties of integrin alpha v beta 3 on human melanoma cells. Cancer Metastasis Rev. 1991 May; 10(1):3-10. Cheresh DA. PMID: 1717171.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    201. Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. J Cell Biol. 1991 May; 113(4):919-29. Wayner EA, Orlando RA, Cheresh DA. PMID: 1709170.
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    202. Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. J Cell Biol. 1991 Apr; 113(2):451-61. Kieffer N, Fitzgerald LA, Wolf D, Cheresh DA, Phillips DR. PMID: 1707057.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    203. Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab patients with Glanzmann thrombasthenia in Israel. Blood. 1991 Jan 01; 77(1):75-83. Coller BS, Cheresh DA, Asch E, Seligsohn U. PMID: 1702031.
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    204. The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin. J Cell Biol. 1990 Dec; 111(6 Pt 1):2795-800. Charo IF, Nannizzi L, Smith JW, Cheresh DA. PMID: 1703545.
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    205. cDNA sequence of the human integrin beta 5 subunit. J Biol Chem. 1990 Oct 05; 265(28):17126-31. McLean JW, Vestal DJ, Cheresh DA, Bodary SC. PMID: 2211615.
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    206. Increased lysis of melanoma by in vivo-elicited human lymphokine-activated killer cells after addition of antiganglioside antibodies in vitro. Cancer Res. 1990 Oct 01; 50(19):6311-5. Harel W, Shau H, Hadley CG, Morgan AC, Reisfeld RA, Cheresh DA, Mitchell MS. PMID: 2400994.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    207. Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells. Blood. 1990 Aug 01; 76(3):570-7. Ylänne J, Cheresh DA, Virtanen I. PMID: 1696147.
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    208. Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites. J Biol Chem. 1990 Jul 25; 265(21):12267-71. Smith JW, Ruggeri ZM, Kunicki TJ, Cheresh DA. PMID: 2373693.
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    209. Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin. J Biol Chem. 1990 Jul 05; 265(19):11008-13. Smith JW, Vestal DJ, Irwin SV, Burke TA, Cheresh DA. PMID: 1694173.
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    210. Cell adhesion mechanisms and their potential impact on wound healing and tumor control. Clin Plast Surg. 1990 Jul; 17(3):457-62. Rudolph R, Cheresh D. PMID: 1696193.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    211. Getting unglued about integrins. The Molecular Basis of Cellular Adhesion: A UCLA symposium, sponsored by Genentech and Glaxo Steamboat Springs, CO, USA, January 20-26, 1990. New Biol. 1990 Jun; 2(6):518-22. Smith JW, Cheresh DA. PMID: 1982422.
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    212. Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor. J Biol Chem. 1990 Feb 05; 265(4):2168-72. Smith JW, Cheresh DA. PMID: 1688848.
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    213. Identification of a novel integrin beta subunit expressed on cultured monocytes (macrophages). Evidence that one alpha subunit can associate with multiple beta subunits. J Biol Chem. 1990 Jan 15; 265(2):823-30. Krissansen GW, Elliott MJ, Lucas CM, Stomski FC, Berndt MC, Cheresh DA, Lopez AF, Burns GF. PMID: 1688554.
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    214. Blood leukocytes bind platelet glycoprotein (IIb-IIIa)' but do not express the vitronectin receptor. Int Immunol. 1990; 2(3):267-77. Krissansen GW, Lucas CM, Stomski FC, Elliott MJ, Berndt MC, Boyd AW, Horton MA, Cheresh DA, Vadas MA, Burns GF. PMID: 1708278.
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    215. Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells. Cell. 1989 Sep 08; 58(5):945-53. Cheresh DA, Berliner SA, Vicente V, Ruggeri ZM. PMID: 2673537.
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    216. Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14.18. Cancer Res. 1989 Jun 01; 49(11):2857-61. Mujoo K, Kipps TJ, Yang HM, Cheresh DA, Wargalla U, Sander DJ, Reisfeld RA. PMID: 2720646.
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    217. RGD-dependent linkage between plant cell wall and plasma membrane: consequences for growth. J Cell Biol. 1989 May; 108(5):1955-65. Schindler M, Meiners S, Cheresh DA. PMID: 2715184.
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    218. A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells. Cell. 1989 Apr 07; 57(1):59-69. Cheresh DA, Smith JW, Cooper HM, Quaranta V. PMID: 2467745.
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    219. Augmentation of lymphocyte responses by monoclonal antibodies to the gangliosides GD3 and GD2: the role of protein kinase C, cyclic nucleotides, and intracellular calcium. Cell Immunol. 1989 Apr 01; 119(2):263-78. Hersey P, Schibeci S, Cheresh D. PMID: 2784717.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    220. Isolation and characterization of a platelet membrane protein related to the vitronectin receptor. J Biol Chem. 1989 Mar 05; 264(7):3742-9. Lam SC, Plow EF, D'Souza SE, Cheresh DA, Frelinger AL, Ginsberg MH. PMID: 2465293.
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    221. Human melanoma cell attachment involves an Arg-Gly-Asp-directed adhesion receptor and the disialoganglioside GD2. Prog Clin Biol Res. 1989; 288:3-24. Cheresh DA. PMID: 2470110.
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    222. Potentiation of interleukin-2 production and its binding by monoclonal antibodies to the gangliosides GD3 and GD2. Cancer Immunol Immunother. 1989; 29(2):109-17. Schibeci S, Hersey P, Cheresh D. PMID: 2524255.
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    223. The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit. J Biol Chem. 1988 Dec 15; 263(35):18726-31. Smith JW, Cheresh DA. PMID: 2461930.
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    224. Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor. J Biol Chem. 1987 Dec 25; 262(36):17703-11. Cheresh DA, Spiro RC. PMID: 2447074.
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    225. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. Proc Natl Acad Sci U S A. 1987 Sep; 84(18):6471-5. Cheresh DA. PMID: 2442758.
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    226. An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2. J Cell Biol. 1987 Sep; 105(3):1163-73. Cheresh DA, Pytela R, Pierschbacher MD, Klier FG, Ruoslahti E, Reisfeld RA. PMID: 2443507.
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    227. Analysis of effector cells in human antibody-dependent cellular cytotoxicity with murine monoclonal antibodies. J Immunol. 1987 May 15; 138(10):3566-72. Ortaldo JR, Woodhouse C, Morgan AC, Herberman RB, Cheresh DA, Reisfeld R. PMID: 2437198.
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    228. Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth. Cancer Res. 1987 Feb 15; 47(4):1098-104. Mujoo K, Cheresh DA, Yang HM, Reisfeld RA. PMID: 3100030.
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    229. Arg-Gly-Asp recognition by a cell adhesion receptor requires its 130-kDa alpha subunit. J Biol Chem. 1987 Feb 05; 262(4):1434-7. Cheresh DA, Harper JR. PMID: 2433281.
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    230. Enhancement of cytotoxic and proliferative responses of lymphocytes from melanoma patients by incubation with monoclonal antibodies against ganglioside GD3. Cancer Immunol Immunother. 1987; 24(2):144-50. Hersey P, MacDonald M, Burns C, Cheresh DA. PMID: 3493846.
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    231. Human tumor antigens. Adv Immunol. 1987; 40:323-77. Reisfeld RA, Cheresh DA. PMID: 3591561.
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    232. Potentiation of lymphocyte responses by monoclonal antibodies to the ganglioside GD3. Cancer Res. 1986 Dec; 46(12 Pt 1):6083-90. Hersey P, Schibeci SD, Townsend P, Burns C, Cheresh DA. PMID: 3022915.
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    233. Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res. 1986 Oct; 46(10):5112-8. Cheresh DA, Rosenberg J, Mujoo K, Hirschowitz L, Reisfeld RA. PMID: 3019521.
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    234. Disialoganglioside GD2 distributes preferentially into substrate-associated microprocesses on human melanoma cells during their attachment to fibronectin. J Cell Biol. 1986 May; 102(5):1887-97. Cheresh DA, Klier FG. PMID: 3084502.
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    235. Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J Cell Biol. 1986 Mar; 102(3):688-96. Cheresh DA, Pierschbacher MD, Herzig MA, Mujoo K. PMID: 3005335.
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    236. Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis. Proc Natl Acad Sci U S A. 1985 Aug; 82(15):5155-9. Cheresh DA, Honsik CJ, Staffileno LK, Jung G, Reisfeld RA. PMID: 3860849.
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    237. Characterization of a membrane surface glycoprotein associated with T-cell activation. J Immunol. 1985 Jul; 135(1):158-64. Sportsman JR, Park MM, Cheresh DA, Fukuda M, Elder JH, Fox RI. PMID: 2987344.
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    238. Structural and functional properties of ganglioside antigens on human tumors of neuroectodermal origin. Surv Synth Pathol Res. 1985; 4(2):97-109. Cheresh DA. PMID: 2996108.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    239. Human tumour-associated antigens: targets for monoclonal antibody-mediated cancer therapy. Cancer Surv. 1985; 4(1):271-90. Reisfeld RA, Cheresh DA. PMID: 3916082.
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    240. Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res. 1984 Dec; 44(12 Pt 1):5914-20. Schulz G, Cheresh DA, Varki NM, Yu A, Staffileno LK, Reisfeld RA. PMID: 6498849.
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    241. Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells. Proc Natl Acad Sci U S A. 1984 Sep; 81(18):5767-71. Cheresh DA, Harper JR, Schulz G, Reisfeld RA. PMID: 6385004.
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    242. O-acetylation of disialoganglioside GD3 by human melanoma cells creates a unique antigenic determinant. Science. 1984 Aug 24; 225(4664):844-6. Cheresh DA, Reisfeld RA, Varki AP. PMID: 6206564.
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    243. A monoclonal antibody recognizes an O-acylated sialic acid in a human melanoma-associated ganglioside. J Biol Chem. 1984 Jun 25; 259(12):7453-9. Cheresh DA, Varki AP, Varki NM, Stallcup WB, Levine J, Reisfeld RA. PMID: 6203895.
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    244. Interaction of an acute phase reactant, alpha 1-acid glycoprotein (orosomucoid), with the lymphoid cell surface: a model for non-specific immune suppression. Immunology. 1984 Mar; 51(3):541-8. Cheresh DA, Haynes DH, Distasio JA. PMID: 6698580.
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    245. Blocked herpes simplex virus type 2-specific DNA synthesis in simian virus 40-transformed hamster cells permissive for herpes simplex virus type 1. Infect Immun. 1983 Aug; 41(2):584-90. Cheresh DA, Haines H. PMID: 6307875.
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    246. Mitogen-induced blastogenesis and receptor mobility inhibition by breast cancer serum with elevated orosomucoid (alpha 1-acid glycoprotein) levels. J Natl Cancer Inst. 1982 May; 68(5):779-83. Cheresh DA, Distasio JA, Vogel CL, Lopez DM. PMID: 6951088.
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    247. Maximizing differences in the concanavalin A-induced blastogenic responses of lymphocytes from breast cancer patients and controls by the use of alpha-methyl-D-mannoside. J Natl Cancer Inst. 1982 Jan; 68(1):68-9. Distasio JA, Cheresh DA, Schilder RJ, Vogel CL, Silverman MA, Lopez DM. PMID: 6948127.
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