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An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility. Sci Adv. 2025 Aug 15; 11(33):eadt0534.
Tan K, Higgins K, Liu Q, Wilkinson MF. PMID: 40802760; PMCID: PMC12346275.
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HumansAnimalsCells
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Biological roles of nonsense-mediated RNA decay: insights from the nervous system. Curr Opin Genet Dev. 2025 Aug; 93:102356.
Tan K, Wilkinson MF. PMID: 40409128.
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HumansAnimalsCells
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Cell type- and factor-specific nonsense-mediated RNA decay. Nucleic Acids Res. 2025 May 10; 53(9).
Tan K, Sebat J, Wilkinson MF. PMID: 40366162; PMCID: PMC12076418.
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PubMed Mentions:
4 Fields:
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HumansAnimalsCells
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A translation regulator that drives spermatogonial stem cell formation. Andrology. 2025 Sep; 13(6):1387-1389.
Tan K, Wilkinson MF. PMID: 39382845.
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HumansAnimalsCells
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Developmental regulators moonlighting as transposons defense factors. Andrology. 2023 07; 11(5):891-903.
Tan K, Wilkinson MF. PMID: 36895139; PMCID: PMC11162177.
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1 Fields:
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HumansCells
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PubMed Mentions:
9 Fields:
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AnimalsCells
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Regulation of both transcription and RNA turnover contribute to germline specification. Nucleic Acids Res. 2022 07 22; 50(13):7310-7325.
Tan K, Wilkinson MF. PMID: 35776114; PMCID: PMC9303369.
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PubMed Mentions:
4 Fields:
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AnimalsCells
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Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2201168119.
Yue Y, Ren L, Zhang C, Miao K, Tan K, Yang Q, Hu Y, Xi G, Luo G, Yang M, Zhang J, Hou Z, An L, Tian J. PMID: 35858425; PMCID: PMC9335330.
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PubMed Mentions:
20 Fields:
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AnimalsCells
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Nonsense-mediated RNA decay: an emerging modulator of malignancy. Nat Rev Cancer. 2022 08; 22(8):437-451.
Tan K, Stupack DG, Wilkinson MF. PMID: 35624152; PMCID: PMC11009036.
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57 Fields:
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HumansCells
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RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade. Cell Rep. 2021 07 20; 36(3):109423.
Tan K, Song HW, Wilkinson MF. PMID: 34289349; PMCID: PMC8357189.
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PubMed Mentions:
13 Fields:
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HumansAnimalsCells
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The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF. PMID: 34083437; PMCID: PMC8201764.
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PubMed Mentions:
11 Fields:
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HumansAnimalsCells
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A single-cell view of spermatogonial stem cells. Curr Opin Cell Biol. 2020 12; 67:71-78.
Tan K, Wilkinson MF. PMID: 32950921; PMCID: PMC7736222.
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PubMed Mentions:
25 Fields:
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HumansAnimalsCells
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The role of the NMD factor UPF3B in olfactory sensory neurons. Elife. 2020 08 10; 9.
Tan K, Jones SH, Lake BB, Chousal JN, Shum EY, Zhang L, Chen S, Sohni A, Pandya S, Gallo RL, Zhang K, Cook-Andersen H, Wilkinson MF. PMID: 32773035; PMCID: PMC7452722.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):17832-17841.
Tan K, Song HW, Thompson M, Munyoki S, Sukhwani M, Hsieh TC, Orwig KE, Wilkinson MF. PMID: 32661178; PMCID: PMC7395452.
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PubMed Mentions:
42 Fields:
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HumansCells
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Single-cell RNAseq analysis of testicular germ and somatic cell development during the perinatal period. Development. 2020 02 03; 147(3).
Tan K, Song HW, Wilkinson MF. PMID: 31964773; PMCID: PMC7033731.
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PubMed Mentions:
68 Fields:
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AnimalsCells
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Response to: X-linked miR-506 family miRNAs promote FMRP expression in mouse spermatogonia. EMBO Rep. 2020 01 07; 21(1):e49354.
Ramaiah M, Tan K, Plank TM, Song HW, Chousal JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. PMID: 31808609; PMCID: PMC6944912.
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PubMed Mentions:
1 Fields:
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AnimalsCells
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Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass. Cell Stem Cell. 2019 02 07; 24(2):201-203.
Tan K, Wilkinson MF. PMID: 30735645; PMCID: PMC6415922.
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16 Fields:
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HumansCells
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The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Rep. 2019 02 05; 26(6):1501-1517.e4.
Sohni A, Tan K, Song HW, Burow D, de Rooij DG, Laurent L, Hsieh TC, Rabah R, Hammoud SS, Vicini E, Wilkinson MF. PMID: 30726734; PMCID: PMC6402825.
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PubMed Mentions:
186 Fields:
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HumansCells
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A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. EMBO Rep. 2019 02; 20(2).
Ramaiah M, Tan K, Plank TM, Song HW, Chousal JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. PMID: 30573526; PMCID: PMC6362356.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Natriuretic peptide receptor 2 (NPR2) localized in bovine oocyte underlies a unique mechanism for C-type natriuretic peptide (CNP)-induced meiotic arrest. Theriogenology. 2018 Jan 15; 106:198-209.
Xi G, An L, Jia Z, Tan K, Zhang J, Wang Z, Zhang C, Miao K, Wu Z, Tian J. PMID: 29080478.
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PubMed Mentions:
21 Fields:
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AnimalsCells
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High-resolution profiles of gene expression and DNA methylation highlight mitochondrial modifications during early embryonic development. J Reprod Dev. 2017 Jun 21; 63(3):247-261.
Ren L, Zhang C, Tao L, Hao J, Tan K, Miao K, Yu Y, Sui L, Wu Z, Tian J, An L. PMID: 28367907; PMCID: PMC5481627.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Downregulation of miR-199a-5p Disrupts the Developmental Potential of In Vitro-Fertilized Mouse Blastocysts. Biol Reprod. 2016 09; 95(3):54.
Tan K, Wang X, Zhang Z, Miao K, Yu Y, An L, Tian J. PMID: 27488027.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Dynamic integrated analysis of DNA methylation and gene expression profiles in in vivo and in vitro fertilized mouse post-implantation extraembryonic and placental tissues. Mol Hum Reprod. 2016 07; 22(7):485-98.
Tan K, Zhang Z, Miao K, Yu Y, Sui L, Tian J, An L. PMID: 27090932.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):3197-202.
Tan K, An L, Miao K, Ren L, Hou Z, Tao L, Zhang Z, Wang X, Xia W, Liu J, Wang Z, Xi G, Gao S, Sui L, Zhu DS, Wang S, Wu Z, Bach I, Chen DB, Tian J. PMID: 26951653; PMCID: PMC4812732.
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PubMed Mentions:
33 Fields:
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HumansCells
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IVF affects embryonic development in a sex-biased manner in mice. Reproduction. 2016 Apr; 151(4):443-53.
Tan K, Wang Z, Zhang Z, An L, Tian J. PMID: 26825929.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos. Hum Reprod. 2015 Dec; 30(12):2892-911.
Ren L, Wang Z, An L, Zhang Z, Tan K, Miao K, Tao L, Cheng L, Zhang Z, Yang M, Wu Z, Tian J. PMID: 26385791.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Actin Disorganization Plays a Vital Role in Impaired Embryonic Development of In Vitro-Produced Mouse Preimplantation Embryos. PLoS One. 2015; 10(6):e0130382.
Tan K, An L, Wang SM, Wang XD, Zhang ZN, Miao K, Sui LL, He SZ, Nie JZ, Wu ZH, Tian JH. PMID: 26076347; PMCID: PMC4468147.
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12 Fields:
Translation:
AnimalsCells
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Generation of fully pluripotent female murine-induced pluripotent stem cells. Biol Reprod. 2015 May; 92(5):123.
Di KQ, Gao S, Cui LF, Chang G, Wu FJ, Ren LK, An L, Miao K, Tan K, Tao L, Chen H, Wang ZL, Wang SM, Wu ZH, Gao S, Li XY, Tian JH. PMID: 25788660.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells. Nat Commun. 2015 Feb 18; 6:6318.
Gao S, Zheng C, Chang G, Liu W, Kou X, Tan K, Tao L, Xu K, Wang H, Cai J, Tian J, Gao S. PMID: 25692725.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Dynamic proteomic profiles of in vivo- and in vitro-produced mouse postimplantation extraembryonic tissues and placentas. Biol Reprod. 2014 Dec; 91(6):155.
Sui L, An L, Tan K, Wang Z, Wang S, Miao K, Ren L, Tao L, He S, Yu Y, Nie J, Liu Q, Xing L, Wu Z, Hou Z, Tian J. PMID: 25320150.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells. Cell Res. 2014 Mar; 24(3):293-306.
Chang G, Gao S, Hou X, Xu Z, Liu Y, Kang L, Tao Y, Liu W, Huang B, Kou X, Chen J, An L, Miao K, Di K, Wang Z, Tan K, Cheng T, Cai T, Gao S, Tian J. PMID: 24381111; PMCID: PMC3945885.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Comparative analysis of dynamic proteomic profiles between in vivo and in vitro produced mouse embryos during postimplantation period. J Proteome Res. 2013 Sep 06; 12(9):3843-56.
Nie J, An L, Miao K, Hou Z, Yu Y, Tan K, Sui L, He S, Liu Q, Lei X, Wu Z, Tian J. PMID: 23841881.
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PubMed Mentions:
15 Fields:
Translation:
Animals