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Kun Tan

Title(s)Assistant Adjunct Professor, Ob/Gyn & Reproductive sciences
SchoolVc-health Sciences-schools
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Decoding the heterogeneity of human undifferentiated spermatogonia reveals RAS-dependent regulation of stem cell fate. Cell Rep. 2026 Feb 24; 45(2):116868. Capponi C, Smith C, Medica A, Hsieh TC, Orwig KE, Tan K. PMID: 41579373.
      View in: PubMed   Mentions:
    2. Clinical features, epidemiology, treatment, and prognosis of multicentre pediatric pneumococcal meningitis in China from 2019 to 2021. BMC Infect Dis. 2025 Dec 24; 25(1):1739. Jian B, Shen G, Liu J, Li W, Li Z, Tan K, Zhou K, Deng H, Li J, Bi J, Jing S, Zhu C, Zhang X, Wang Y, Li J, Chen B, Dong F, Zhao S, Wang L, Ning X, Zhu L, Li L, Huang C, Jia L, Wang F, Deng J, Shan M, Cai H, Liu S, Jiang T, Wang Y, Zhou Y, Liang J, Ye L, Lu X, Sun J, Zhao Q, Wang H, Zhang B, Yao K, Yang Y, Liu G. PMID: 41444504; PMCID: PMC12729672.
      View in: PubMed   Mentions:    Fields:    
    3. Astrocytic RNA degradation suppresses calcium signaling to support synapse function and restrain anxiety. bioRxiv. 2025 Nov 18. Lituma PJ, Deveci A, Barrio-Alonso E, Tan K, Wilkinson MF, Castillo PE, Colak D. PMID: 41332760; PMCID: PMC12667954.
      View in: PubMed   Mentions:
    4. Genetic variants reshape the m6A epitranscriptome and drive transcriptomic reprogramming in colorectal cancer. Sci Rep. 2025 Nov 11; 15(1):39384. Han SH, Jang S, Kim Y, Tan K, Wilkinson MF, Jeong H, Choe J. PMID: 41219359; PMCID: PMC12606336.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Integrated clinical and single-cell profiling of BCMA CAR-T therapy in relapsed/refractory multiple myeloma. J Transl Med. 2025 Nov 10; 23(1):1251. Fang C, Wang L, Zhao W, Wang L, Huang W, Chen Z, Wang Y, Tan K, Guo X, Xu Y, Wang S, Wang L, Qiao J, Meng X, He Z, Yu C, Mei J, Wang H, Li Y, Yu L. PMID: 41214679; PMCID: PMC12604393.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility. Sci Adv. 2025 Aug 15; 11(33):eadt0534. Tan K, Higgins K, Liu Q, Wilkinson MF. PMID: 40802760; PMCID: PMC12346275.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Biological roles of nonsense-mediated RNA decay: insights from the nervous system. Curr Opin Genet Dev. 2025 Aug; 93:102356. Tan K, Wilkinson MF. PMID: 40409128.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Cell type- and factor-specific nonsense-mediated RNA decay. Nucleic Acids Res. 2025 May 10; 53(9). Tan K, Sebat J, Wilkinson MF. PMID: 40366162; PMCID: PMC12076418.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    9. Contaminated faucets and sinks as a reservoir for antibiotic-resistant bacterial transmission in healthcare settings. J Infect Dev Ctries. 2025 Jan 31; 19(1):98-106. Li Q, Ding H, Chen Z, Li W, Tan K, Xu C, Zou M, Wang X, Tan L. PMID: 39977473.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    10. A translation regulator that drives spermatogonial stem cell formation. Andrology. 2025 Sep; 13(6):1387-1389. Tan K, Wilkinson MF. PMID: 39382845.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Long-term outcomes of left bundle branch area pacing compared with right ventricular pacing in TAVI patients. Heart Rhythm. 2025 Jul; 22(7):1774-1781. Wang X, Xu Y, Zeng L, Tan K, Zhang X, Han X, Xiong T, Zhao Z, Peng Y, Wei J, Li Q, He S, Chen Y, Zhou M, Li X, Wei X, Liang Y, Zhou W, Jiang L, Liu X, Meng W, Zhou R, Xiong G, Dai M, Deng X, Feng Y, Chen M. PMID: 39288882.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Bispecific CAR-T cells targeting CD19/20 in patients with relapsed or refractory B cell non-Hodgkin lymphoma: a phase I/II trial. Blood Cancer J. 2024 08 07; 14(1):130. Wang L, Fang C, Kang Q, Huang W, Chen Z, Zhao W, Wang L, Wang Y, Tan K, Guo X, Xu Y, Wang S, Wang L, Qiao J, Tang Z, Yu C, Xu Y, Li Y, Yu L. PMID: 39112452; PMCID: PMC11306243.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    13. Invasive pneumococcal diseases in Chinese children: a multicentre hospital-based active surveillance from 2019 to 2021. Emerg Microbes Infect. 2024 Dec; 13(1):2332670. Ning X, Li L, Liu J, Wang F, Tan K, Li W, Zhou K, Jing S, Lin A, Bi J, Zhao S, Deng H, Zhu C, Lv S, Li J, Liang J, Zhao Q, Wang Y, Chen B, Zhu L, Shen G, Liu J, Li Z, Deng J, Zhao X, Shan M, Wang Y, Liu S, Jiang T, Chen X, Zhang Y, Cai S, Wang L, Lu X, Jiang J, Dong F, Ye L, Sun J, Yao K, Yang Y, Liu G. PMID: 38646911; PMCID: PMC11047219.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    14. The endoplasmic reticulum stress-related genes and molecular typing predicts prognosis and reveals characterization of tumor immune microenvironment in lung squamous cell carcinoma. Discov Oncol. 2024 Feb 16; 15(1):37. Wang R, Huang Y, He J, Jin S, Li X, Tan K, Xia W. PMID: 38363409; PMCID: PMC10873263.
      View in: PubMed   Mentions: 2  
    15. Ambient particulate matter and in-hospital case fatality of acute myocardial infarction: A multi-province cross-sectional study in China. Ecotoxicol Environ Saf. 2023 Dec; 268:115731. Lin X, Cai M, Tan K, Liu E, Wang X, Song C, Wei J, Lin H, Pan J. PMID: 38007949.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    16. Estimation of the distribution patterns of heavy metal in soil from airborne hyperspectral imagery based on spectral absorption characteristics. J Environ Manage. 2023 Dec 01; 347:119196. Tan K, Chen L, Wang H, Liu Z, Ding J, Wang X. PMID: 37801949.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    17. Developmental regulators moonlighting as transposons defense factors. Andrology. 2023 07; 11(5):891-903. Tan K, Wilkinson MF. PMID: 36895139; PMCID: PMC11162177.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis. Nucleic Acids Res. 2022 11 11; 50(20):11470-11491. Lehtiniemi T, Bourgery M, Ma L, Ahmedani A, Mäkelä M, Asteljoki J, Olotu O, Laasanen S, Zhang FP, Tan K, Chousal JN, Burow D, Koskinen S, Laiho A, Elo LL, Chalmel F, Wilkinson MF, Kotaja N. PMID: 36259644; PMCID: PMC9723633.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Progression of the pluripotent epiblast depends upon the NMD factor UPF2. Development. 2022 11 01; 149(21). Chousal JN, Sohni A, Vitting-Seerup K, Cho K, Kim M, Tan K, Porse B, Wilkinson MF, Cook-Andersen H. PMID: 36255229; PMCID: PMC9687065.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    20. Regulation of both transcription and RNA turnover contribute to germline specification. Nucleic Acids Res. 2022 07 22; 50(13):7310-7325. Tan K, Wilkinson MF. PMID: 35776114; PMCID: PMC9303369.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    21. Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2201168119. Yue Y, Ren L, Zhang C, Miao K, Tan K, Yang Q, Hu Y, Xi G, Luo G, Yang M, Zhang J, Hou Z, An L, Tian J. PMID: 35858425; PMCID: PMC9335330.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    22. Nonsense-mediated RNA decay: an emerging modulator of malignancy. Nat Rev Cancer. 2022 08; 22(8):437-451. Tan K, Stupack DG, Wilkinson MF. PMID: 35624152; PMCID: PMC11009036.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    23. Development of a soil heavy metal estimation method based on a spectral index: Combining fractional-order derivative pretreatment and the absorption mechanism. Sci Total Environ. 2022 Mar 20; 813:151882. Chen L, Lai J, Tan K, Wang X, Chen Y, Ding J. PMID: 34822891.
      View in: PubMed   Mentions: 9     Fields:    Translation:PHPublic Health
    24. Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study. BMC Infect Dis. 2021 Nov 15; 21(1):1156. Chen TM, Li WH, Wang F, Tan K, Zhu QX, Zhou K, Liu SH, Liu J, Bi J, Deng HL, Chen XX, Li J, Wang YM, Zhao Q, Zhu L, Ma HX, Li Z, Deng JK, Zhu CH, Wu KK, Lin AW, Li SJ, Wang DM, Cai HJ, Zhao SY, Lu XD, Ye L, Dong F, Zhang WS, Yang YH, Liu G. PMID: 34775956; PMCID: PMC8591947.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade. Cell Rep. 2021 07 20; 36(3):109423. Tan K, Song HW, Wilkinson MF. PMID: 34289349; PMCID: PMC8357189.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    26. The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 06 08; 118(23). Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF. PMID: 34083437; PMCID: PMC8201764.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    27. A single-cell view of spermatogonial stem cells. Curr Opin Cell Biol. 2020 12; 67:71-78. Tan K, Wilkinson MF. PMID: 32950921; PMCID: PMC7736222.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    28. The role of the NMD factor UPF3B in olfactory sensory neurons. Elife. 2020 08 10; 9. Tan K, Jones SH, Lake BB, Chousal JN, Shum EY, Zhang L, Chen S, Sohni A, Pandya S, Gallo RL, Zhang K, Cook-Andersen H, Wilkinson MF. PMID: 32773035; PMCID: PMC7452722.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    29. Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):17832-17841. Tan K, Song HW, Thompson M, Munyoki S, Sukhwani M, Hsieh TC, Orwig KE, Wilkinson MF. PMID: 32661178; PMCID: PMC7395452.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    30. Single-cell RNAseq analysis of testicular germ and somatic cell development during the perinatal period. Development. 2020 02 03; 147(3). Tan K, Song HW, Wilkinson MF. PMID: 31964773; PMCID: PMC7033731.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    31. Response to: X-linked miR-506 family miRNAs promote FMRP expression in mouse spermatogonia. EMBO Rep. 2020 01 07; 21(1):e49354. Ramaiah M, Tan K, Plank TM, Song HW, Chousal JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. PMID: 31808609; PMCID: PMC6944912.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    32. Genomic characterization of a novel recombinant porcine astrovirus isolated in northeastern China. Arch Virol. 2019 May; 164(5):1469-1473. Zhao C, Chen C, Li Y, Dong S, Tan K, Tian Y, Zhang L, Huang J, Zhang L. PMID: 30868264.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    33. Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass. Cell Stem Cell. 2019 02 07; 24(2):201-203. Tan K, Wilkinson MF. PMID: 30735645; PMCID: PMC6415922.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Rep. 2019 02 05; 26(6):1501-1517.e4. Sohni A, Tan K, Song HW, Burow D, de Rooij DG, Laurent L, Hsieh TC, Rabah R, Hammoud SS, Vicini E, Wilkinson MF. PMID: 30726734; PMCID: PMC6402825.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansCells
    35. A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. EMBO Rep. 2019 02; 20(2). Ramaiah M, Tan K, Plank TM, Song HW, Chousal JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. PMID: 30573526; PMCID: PMC6362356.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    36. Natriuretic peptide receptor 2 (NPR2) localized in bovine oocyte underlies a unique mechanism for C-type natriuretic peptide (CNP)-induced meiotic arrest. Theriogenology. 2018 Jan 15; 106:198-209. Xi G, An L, Jia Z, Tan K, Zhang J, Wang Z, Zhang C, Miao K, Wu Z, Tian J. PMID: 29080478.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    37. High-resolution profiles of gene expression and DNA methylation highlight mitochondrial modifications during early embryonic development. J Reprod Dev. 2017 Jun 21; 63(3):247-261. Ren L, Zhang C, Tao L, Hao J, Tan K, Miao K, Yu Y, Sui L, Wu Z, Tian J, An L. PMID: 28367907; PMCID: PMC5481627.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    38. Downregulation of miR-199a-5p Disrupts the Developmental Potential of In Vitro-Fertilized Mouse Blastocysts. Biol Reprod. 2016 09; 95(3):54. Tan K, Wang X, Zhang Z, Miao K, Yu Y, An L, Tian J. PMID: 27488027.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    39. Dynamic integrated analysis of DNA methylation and gene expression profiles in in vivo and in vitro fertilized mouse post-implantation extraembryonic and placental tissues. Mol Hum Reprod. 2016 07; 22(7):485-98. Tan K, Zhang Z, Miao K, Yu Y, Sui L, Tian J, An L. PMID: 27090932.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    40. Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):3197-202. Tan K, An L, Miao K, Ren L, Hou Z, Tao L, Zhang Z, Wang X, Xia W, Liu J, Wang Z, Xi G, Gao S, Sui L, Zhu DS, Wang S, Wu Z, Bach I, Chen DB, Tian J. PMID: 26951653; PMCID: PMC4812732.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    41. IVF affects embryonic development in a sex-biased manner in mice. Reproduction. 2016 Apr; 151(4):443-53. Tan K, Wang Z, Zhang Z, An L, Tian J. PMID: 26825929.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    42. Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos. Hum Reprod. 2015 Dec; 30(12):2892-911. Ren L, Wang Z, An L, Zhang Z, Tan K, Miao K, Tao L, Cheng L, Zhang Z, Yang M, Wu Z, Tian J. PMID: 26385791.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    43. Actin Disorganization Plays a Vital Role in Impaired Embryonic Development of In Vitro-Produced Mouse Preimplantation Embryos. PLoS One. 2015; 10(6):e0130382. Tan K, An L, Wang SM, Wang XD, Zhang ZN, Miao K, Sui LL, He SZ, Nie JZ, Wu ZH, Tian JH. PMID: 26076347; PMCID: PMC4468147.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    44. Generation of fully pluripotent female murine-induced pluripotent stem cells. Biol Reprod. 2015 May; 92(5):123. Di KQ, Gao S, Cui LF, Chang G, Wu FJ, Ren LK, An L, Miao K, Tan K, Tao L, Chen H, Wang ZL, Wang SM, Wu ZH, Gao S, Li XY, Tian JH. PMID: 25788660.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    45. Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells. Nat Commun. 2015 Feb 18; 6:6318. Gao S, Zheng C, Chang G, Liu W, Kou X, Tan K, Tao L, Xu K, Wang H, Cai J, Tian J, Gao S. PMID: 25692725.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    46. Dynamic proteomic profiles of in vivo- and in vitro-produced mouse postimplantation extraembryonic tissues and placentas. Biol Reprod. 2014 Dec; 91(6):155. Sui L, An L, Tan K, Wang Z, Wang S, Miao K, Ren L, Tao L, He S, Yu Y, Nie J, Liu Q, Xing L, Wu Z, Hou Z, Tian J. PMID: 25320150.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    47. High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells. Cell Res. 2014 Mar; 24(3):293-306. Chang G, Gao S, Hou X, Xu Z, Liu Y, Kang L, Tao Y, Liu W, Huang B, Kou X, Chen J, An L, Miao K, Di K, Wang Z, Tan K, Cheng T, Cai T, Gao S, Tian J. PMID: 24381111; PMCID: PMC3945885.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    48. Comparative analysis of dynamic proteomic profiles between in vivo and in vitro produced mouse embryos during postimplantation period. J Proteome Res. 2013 Sep 06; 12(9):3843-56. Nie J, An L, Miao K, Hou Z, Yu Y, Tan K, Sui L, He S, Liu Q, Lei X, Wu Z, Tian J. PMID: 23841881.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
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