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Gene Amplification of Mediator Subunit 30 Redirects the MYC Transcriptional Program and Oncogenesis. Res Sq. 2024 May 06.
Jin C, Zhao L, Zhao G, Liu Y, Ma W, Ma S, Yao L, Liu Y, Wu Q, Yuan H, Yang K, Ohgi K, Rich JN, Rosenfeld MG. PMID: 38766212; PMCID: PMC11100879.
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PubMed Mentions:
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A systems biology-based identification and in vivo functional screening of Alzheimer's disease risk genes reveal modulators of memory function. Neuron. 2024 Jul 03; 112(13):2112-2129.e4.
Hudgins AD, Zhou S, Arey RN, Rosenfeld MG, Murphy CT, Suh Y. PMID: 38692279; PMCID: PMC11223975.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Enhancer-promoter specificity in gene transcription: molecular mechanisms and disease associations. Exp Mol Med. 2024 Apr; 56(4):772-787.
Friedman MJ, Wagner T, Lee H, Rosenfeld MG, Oh S. PMID: 38658702; PMCID: PMC11058250.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proc Natl Acad Sci U S A. 2024 Jan 09; 121(2):e2316104121.
Abe Y, Kofman ER, Ouyang Z, Cruz-Becerra G, Spann NJ, Seidman JS, Troutman TD, Stender JD, Taylor H, Fan W, Link VM, Shen Z, Sakai J, Downes M, Evans RM, Kadonaga JT, Rosenfeld MG, Glass CK. PMID: 38165941; PMCID: PMC10786282.
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PubMed Mentions: Fields:
Translation:
Cells
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EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma. Mol Cell. 2023 Dec 07; 83(23):4334-4351.e7.
Lv D, Zhong C, Dixit D, Yang K, Wu Q, Godugu B, Prager BC, Zhao G, Wang X, Xie Q, Bao S, He C, Heiland DH, Rosenfeld MG, Rich JN. PMID: 37979586; PMCID: PMC10842222.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Ultrafine mapping of chromosome conformation at hundred basepair resolution reveals regulatory genome architecture. Proc Natl Acad Sci U S A. 2023 Nov 07; 120(45):e2313285120.
Zhu Y, Rosenfeld MG, Suh Y. PMID: 37922325; PMCID: PMC10636305.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression. Mol Cell. 2023 10 05; 83(19):3421-3437.e11.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK. PMID: 37751740; PMCID: PMC10591845.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16INK4a. Aging Cell. 2023 09; 22(9):e13908.
Zhu Y, Tazearslan C, Rosenfeld MG, Fiser A, Suh Y. PMID: 37345431; PMCID: PMC10497822.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16 INK4a. bioRxiv. 2023 May 22.
Zhu Y, Tazearslan C, Rosenfeld MG, Fiser A, Suh Y. PMID: 37292862; PMCID: PMC10245730.
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Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nat Struct Mol Biol. 2023 02; 30(2):148-158.
Tan Y, Yao L, Gamliel A, Nair SJ, Taylor H, Ohgi K, Aggarwal AK, Rosenfeld MG. PMID: 36747093; PMCID: PMC9935399.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Long-distance association of topological boundaries through nuclear condensates. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2206216119.
Gamliel A, Meluzzi D, Oh S, Jiang N, Destici E, Rosenfeld MG, Nair SJ. PMID: 35914133; PMCID: PMC9371644.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Transcriptional enhancers at 40: evolution of a viral DNA element to nuclear architectural structures. Trends Genet. 2022 10; 38(10):1019-1047.
Nair SJ, Suter T, Wang S, Yang L, Yang F, Rosenfeld MG. PMID: 35811173; PMCID: PMC9474616.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Author Correction: Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes. Nature. 2022 Jul; 607(7919):E11.
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. PMID: 35790797.
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PubMed Mentions: Fields:
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An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation. Blood. 2021 11 04; 138(18):1691-1704.
Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim KC, Engel JD. PMID: 34324630; PMCID: PMC8569417.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation. PLoS One. 2021; 16(9):e0257265.
Kim SS, Hudgins AD, Yang J, Zhu Y, Tu Z, Rosenfeld MG, DiLorenzo TP, Suh Y. PMID: 34529725; PMCID: PMC8445446.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Shape of promoter antisense RNAs regulates ligand-induced transcription activation. Nature. 2021 07; 595(7867):444-449.
Yang F, Tanasa B, Micheletti R, Ohgi KA, Aggarwal AK, Rosenfeld MG. PMID: 34194047; PMCID: PMC8439151.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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A transcriptional switch governs fibroblast activation in heart disease. Nature. 2021 07; 595(7867):438-443.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. PMID: 34163071; PMCID: PMC8341289.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Enhancer release and retargeting activates disease-susceptibility genes. Nature. 2021 07; 595(7869):735-740.
Oh S, Shao J, Mitra J, Xiong F, D'Antonio M, Wang R, Garcia-Bassets I, Ma Q, Zhu X, Lee JH, Nair SJ, Yang F, Ohgi K, Frazer KA, Zhang ZD, Li W, Rosenfeld MG. PMID: 34040254; PMCID: PMC11171441.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Hippo signalling maintains ER expression and ER+ breast cancer growth. Nature. 2021 03; 591(7848):E1-E10.
Ma S, Wu Z, Yang F, Zhang J, Johnson RL, Rosenfeld MG, Guan KL. PMID: 33658690; PMCID: PMC8725601.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis. Adv Sci (Weinh). 2021 05; 8(9):2004635.
Shen HF, Zhang WJ, Huang Y, He YH, Hu GS, Wang L, Peng BL, Yi J, Li TT, Rong R, Chen XY, Liu JY, Li WJ, Ohgi K, Li SW, Rosenfeld MG, Liu W. PMID: 33977073; PMCID: PMC8097366.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Signalosome-Regulated Serum Response Factor Phosphorylation Determining Myocyte Growth in Width Versus Length as a Therapeutic Target for Heart Failure. Circulation. 2020 12; 142(22):2138-2154.
Li J, Tan Y, Passariello CL, Martinez EC, Kritzer MD, Li X, Li X, Li Y, Yu Q, Ohgi K, Thakur H, MacArthur JW, Ivey JR, Woo YJ, Emter CA, Dodge-Kafka K, Rosenfeld MG, Kapiloff MS. PMID: 32933333; PMCID: PMC7704863.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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The DNA methyltransferase DNMT3A contributes to autophagy long-term memory. Autophagy. 2021 05; 17(5):1259-1277.
González-Rodríguez P, Cheray M, Füllgrabe J, Salli M, Engskog-Vlachos P, Keane L, Cunha V, Lupa A, Li W, Ma Q, Dreij K, Rosenfeld MG, Joseph B. PMID: 32876528; PMCID: PMC8143216.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21618-21627.
Park A, Oh S, Jung KL, Choi UY, Lee HR, Rosenfeld MG, Jung JU. PMID: 32817485; PMCID: PMC7474655.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor. Cell Rep. 2020 06 23; 31(12):107803.
Yang M, Lee JH, Zhang Z, De La Rosa R, Bi M, Tan Y, Liao Y, Hong J, Du B, Wu Y, Scheirer J, Hong T, Li W, Fei T, Hsieh CL, Liu Z, Li W, Rosenfeld MG, Xu K. PMID: 32579929; PMCID: PMC8564762.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. Nat Commun. 2020 04 29; 11(1):2082.
Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M. PMID: 32350257; PMCID: PMC7190832.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Reorganized 3D Genome Structures Support Transcriptional Regulation in Mouse Spermatogenesis. iScience. 2020 Apr 24; 23(4):101034.
Luo Z, Wang X, Jiang H, Wang R, Chen J, Chen Y, Xu Q, Cao J, Gong X, Wu J, Yang Y, Li W, Han C, Cheng CY, Rosenfeld MG, Sun F, Song X. PMID: 32315832; PMCID: PMC7170994.
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PubMed Mentions:
20
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Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell. 2020 03 19; 180(6):1212-1227.e14.
Gou LT, Lim DH, Ma W, Aubol BE, Hao Y, Wang X, Zhao J, Liang Z, Shao C, Zhang X, Meng F, Li H, Zhang X, Xu R, Li D, Rosenfeld MG, Mellon PL, Adams JA, Liu MF, Fu XD. PMID: 32169215; PMCID: PMC7190278.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139.
Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856; PMCID: PMC7028213.
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PubMed Mentions:
276 Fields:
Translation:
HumansCells
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Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. Nat Genet. 2019 10; 51(10):1506-1517.
Benaglio P, D'Antonio-Chronowska A, Ma W, Yang F, Young Greenwald WW, Donovan MKR, DeBoever C, Li H, Drees F, Singhal S, Matsui H, van Setten J, Sotoodehnia N, Gaulton KJ, Smith EN, D'Antonio M, Rosenfeld MG, Frazer KA. PMID: 31570892; PMCID: PMC6858543.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly. Nat Struct Mol Biol. 2019 03; 26(3):193-203.
Nair SJ, Yang L, Meluzzi D, Oh S, Yang F, Friedman MJ, Wang S, Suter T, Alshareedah I, Gamliel A, Ma Q, Zhang J, Hu Y, Tan Y, Ohgi KA, Jayani RS, Banerjee PR, Aggarwal AK, Rosenfeld MG. PMID: 30833784; PMCID: PMC6709854.
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PubMed Mentions:
147 Fields:
Translation:
HumansCells
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The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus. Mol Cell. 2018 09 06; 71(5):872.
Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. PMID: 30193100; PMCID: PMC6173192.
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PubMed Mentions:
5 Fields:
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Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program. Mol Cell. 2018 08 16; 71(4):526-539.e8.
Tan Y, Jin C, Ma W, Hu Y, Tanasa B, Oh S, Gamliel A, Ma Q, Yao L, Zhang J, Ohgi K, Liu W, Aggarwal AK, Rosenfeld MG. PMID: 30118678; PMCID: PMC6149533.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells. Nature. 2018 04; 556(7702):510-514.
Kim HS, Tan Y, Ma W, Merkurjev D, Destici E, Ma Q, Suter T, Ohgi K, Friedman M, Skowronska-Krawczyk D, Rosenfeld MG. PMID: 29670286; PMCID: PMC6021123.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex. Mol Cell. 2018 04 19; 70(2):340-357.e8.
Gao WW, Xiao RQ, Zhang WJ, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W. PMID: 29628309; PMCID: PMC6258263.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Mol Cell. 2018 03 01; 69(5):757-772.e7.
Cardamone MD, Tanasa B, Cederquist CT, Huang J, Mahdaviani K, Li W, Rosenfeld MG, Liesa M, Perissi V. PMID: 29499132; PMCID: PMC6022402.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E244-E252.
Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, Glass CK, Rosenfeld MG. PMID: 29263096; PMCID: PMC5777077.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis. Nat Neurosci. 2017 Nov; 20(11):1520-1528.
Glasgow SM, Carlson JC, Zhu W, Chaboub LS, Kang P, Lee HK, Clovis YM, Lozzi BE, McEvilly RJ, Rosenfeld MG, Creighton CJ, Lee SK, Mohila CA, Deneen B. PMID: 28892058; PMCID: PMC5919190.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10107-10112.
Gao X, Lee HY, Li W, Platt RJ, Barrasa MI, Ma Q, Elmes RR, Rosenfeld MG, Lodish HF. PMID: 28864529; PMCID: PMC5617304.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Physiological functions of programmed DNA breaks in signal-induced transcription. Nat Rev Mol Cell Biol. 2017 08; 18(8):471-476.
Puc J, Aggarwal AK, Rosenfeld MG. PMID: 28537575; PMCID: PMC5854152.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program. Mol Cell. 2017 May 04; 66(3):321-331.e6.
Yang F, Ma Q, Liu Z, Li W, Tan Y, Jin C, Ma W, Hu Y, Shen J, Ohgi KA, Telese F, Liu W, Rosenfeld MG. PMID: 28475868; PMCID: PMC5510478.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Corrigendum: The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature. 2017 03 30; 543(7647):742.
Füllgrabe J, Lynch-Day MA, Heldring N, Li W, Struijk RB, Ma Q, Hermanson O, Rosenfeld MG, Klionsky DJ, Joseph B. PMID: 28297710.
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PubMed Mentions:
3 Fields:
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Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. Cancers (Basel). 2017 Jan 16; 9(1).
Cucchiara V, Yang JC, Mirone V, Gao AC, Rosenfeld MG, Evans CP. PMID: 28275218; PMCID: PMC5295780.
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PubMed Mentions:
17
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REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E406-E415.
Monaghan CE, Nechiporuk T, Jeng S, McWeeney SK, Wang J, Rosenfeld MG, Mandel G. PMID: 28049845; PMCID: PMC5255626.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Epithelial cell integrin β1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13408-13413.
Scully KM, Skowronska-Krawczyk D, Krawczyk M, Merkurjev D, Taylor H, Livolsi A, Tollkuhn J, Stan RV, Rosenfeld MG. PMID: 27810956; PMCID: PMC5127350.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins. Elife. 2016 06 02; 5.
Chen L, Liu Z, Zhou B, Wei C, Zhou Y, Rosenfeld MG, Fu XD, Chisholm AD, Jin Y. PMID: 27253061; PMCID: PMC4946901.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Enhancers as non-coding RNA transcription units: recent insights and future perspectives. Nat Rev Genet. 2016 Apr; 17(4):207-23.
Li W, Notani D, Rosenfeld MG. PMID: 26948815.
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PubMed Mentions:
371 Fields:
Translation:
HumansAnimalsCells
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Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7).
Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. PMID: 26823525; PMCID: PMC4948565.
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PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland. Stem Cell Reports. 2015 Dec 08; 5(6):1196-1209.
Zhu X, Tollkuhn J, Taylor H, Rosenfeld MG. PMID: 26651607; PMCID: PMC4682291.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. Mol Cell. 2015 Sep 17; 59(6):931-40.
Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, Wen C, Krupa M, Luo H, Ouyang H, Lin D, Wang W, Li G, Xu Y, Li O, Chung C, Yeh E, Jafari M, Ai M, Zhong Z, Shi W, Zheng L, Krawczyk M, Chen D, Shi C, Zin C, Zhu J, Mellon PL, Gao W, Abagyan R, Zhang L, Sun X, Zhong S, Zhuo Y, Rosenfeld MG, Liu Y, Zhang K. PMID: 26365380; PMCID: PMC4648709.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control. Nat Neurosci. 2015 Sep; 18(9):1256-64.
Wang J, Telese F, Tan Y, Li W, Jin C, He X, Basnet H, Ma Q, Merkurjev D, Zhu X, Liu Z, Zhang J, Ohgi K, Taylor H, White RR, Tazearslan C, Suh Y, Macfarlan TS, Pfaff SL, Rosenfeld MG. PMID: 26214369; PMCID: PMC4625987.
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PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
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Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation. Mol Cell. 2015 Jul 16; 59(2):188-202.
Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, Zhou X, Liu Z, Tanasa B, He X, Chen AY, Ohgi K, Zhang J, Liu W, Rosenfeld MG. PMID: 26166704; PMCID: PMC5770188.
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PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3327-36.
Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W. PMID: 26080448; PMCID: PMC4491752.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron. 2015 May 06; 86(3):696-710.
Telese F, Ma Q, Perez PM, Notani D, Oh S, Li W, Comoletti D, Ohgi KA, Taylor H, Rosenfeld MG. PMID: 25892301; PMCID: PMC4486257.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
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The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation. Immunity. 2015 Feb 17; 42(2):252-264.
Lee JY, Skon CN, Lee YJ, Oh S, Taylor JJ, Malhotra D, Jenkins MK, Rosenfeld MG, Hogquist KA, Jameson SC. PMID: 25692701; PMCID: PMC4409658.
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PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
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An epigenomic role of Fe65 in the cellular response to DNA damage. Mutat Res. 2015 Jun; 776:40-7.
Ryu S, Teles F, Minopoli G, Russo T, Rosenfeld MG, Suh Y. PMID: 26255939; PMCID: PMC4531264.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Ligand-dependent enhancer activation regulated by topoisomerase-I activity. Cell. 2015 Jan 29; 160(3):367-80.
Puc J, Kozbial P, Li W, Tan Y, Liu Z, Suter T, Ohgi KA, Zhang J, Aggarwal AK, Rosenfeld MG. PMID: 25619691; PMCID: PMC4422651.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells
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Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1380-5.
Zhang F, Tanasa B, Merkurjev D, Lin C, Song X, Li W, Tan Y, Liu Z, Zhang J, Ohgi KA, Krones A, Skowronska-Krawczyk D, Rosenfeld MG. PMID: 25605944; PMCID: PMC4321301.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Enhancer activation requires trans-recruitment of a mega transcription factor complex. Cell. 2014 Oct 09; 159(2):358-73.
Liu Z, Merkurjev D, Yang F, Li W, Oh S, Friedman MJ, Song X, Zhang F, Ma Q, Ohgi KA, Krones A, Rosenfeld MG. PMID: 25303530; PMCID: PMC4465761.
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PubMed Mentions:
108 Fields:
Translation:
HumansCells
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Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014 Dec 11; 516(7530):267-71.
Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. PMID: 25252977; PMCID: PMC4461219.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases. Stem Cell Reports. 2014 Sep 09; 3(3):502-15.
Castelo-Branco G, Lilja T, Wallenborg K, Falcão AM, Marques SC, Gracias A, Solum D, Paap R, Walfridsson J, Teixeira AI, Rosenfeld MG, Jepsen K, Hermanson O. PMID: 25241747; PMCID: PMC4266002.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature. 2014 Oct 09; 514(7521):257-61.
Skowronska-Krawczyk D, Ma Q, Schwartz M, Scully K, Li W, Liu Z, Taylor H, Tollkuhn J, Ohgi KA, Notani D, Kohwi Y, Kohwi-Shigematsu T, Rosenfeld MG. PMID: 25119036; PMCID: PMC4358797.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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CtBPs sense microenvironmental oxygen levels to regulate neural stem cell state. Cell Rep. 2014 Aug 07; 8(3):665-70.
Dias JM, Ilkhanizadeh S, Karaca E, Duckworth JK, Lundin V, Rosenfeld MG, Ericson J, Hermanson O, Teixeira AI. PMID: 25088415.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Willingness of international delegations to be deployed to areas with high risk of radiation. Prehosp Disaster Med. 2014 Aug; 29(4):369-73.
Shenhar G, Radomislensky I, Rosenfeld M, Peleg K. PMID: 25007172.
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PubMed Mentions: Fields:
Translation:
Humans
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GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ. Cell Rep. 2014 Jul 10; 8(1):163-76.
Cardamone MD, Tanasa B, Chan M, Cederquist CT, Andricovich J, Rosenfeld MG, Perissi V. PMID: 24953653; PMCID: PMC4104678.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9235-40.
Jin C, Yang L, Xie M, Lin C, Merkurjev D, Yang JC, Tanasa B, Oh S, Zhang J, Ohgi KA, Zhou H, Li W, Evans CP, Ding S, Rosenfeld MG. PMID: 24928520; PMCID: PMC4078819.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82.
Lam MT, Li W, Rosenfeld MG, Glass CK. PMID: 24674738; PMCID: PMC4266492.
View in:
PubMed Mentions:
263 Fields:
Translation:
HumansAnimalsCells
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Complexity of the RAR-mediated transcriptional regulatory programs. Subcell Biochem. 2014; 70:203-25.
Liu Z, Hu Q, Rosenfeld MG. PMID: 24962887.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell. 2013 Dec 19; 155(7):1581-1595.
Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, Aggarwal A, Rosenfeld MG. PMID: 24360279; PMCID: PMC3886918.
View in:
PubMed Mentions:
225 Fields:
Translation:
HumansCells
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lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs. Nature. 2013 Aug 29; 500(7464):598-602.
Yang L, Lin C, Jin C, Yang JC, Tanasa B, Li W, Merkurjev D, Ohgi KA, Meng D, Zhang J, Evans CP, Rosenfeld MG. PMID: 23945587; PMCID: PMC4034386.
View in:
PubMed Mentions:
364 Fields:
Translation:
HumansAnimalsCells
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The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature. 2013 Aug 22; 500(7463):468-71.
Füllgrabe J, Lynch-Day MA, Heldring N, Li W, Struijk RB, Ma Q, Hermanson O, Rosenfeld MG, Klionsky DJ, Joseph B. PMID: 23863932; PMCID: PMC4006103.
View in:
PubMed Mentions:
184 Fields:
Translation:
HumansCells
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Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 2013 Jun 27; 498(7455):516-20.
Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim HS, Glass CK, Rosenfeld MG. PMID: 23728302; PMCID: PMC3718886.
View in:
PubMed Mentions:
536 Fields:
Translation:
HumansCells
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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5.
Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. PMID: 23728303; PMCID: PMC3839578.
View in:
PubMed Mentions:
320 Fields:
Translation:
AnimalsCells
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The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. PLoS One. 2013; 8(5):e59986.
Scafoglio C, Smolka M, Zhou H, Perissi V, Rosenfeld MG. PMID: 23690919; PMCID: PMC3656868.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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TCF7L2 variation and proliferative diabetic retinopathy. Diabetes. 2013 Jul; 62(7):2613-7.
Luo J, Zhao L, Chen AY, Zhang X, Zhu J, Zhao J, Ouyang H, Luo H, Song Y, Lee J, Patel SH, Shaw PX, Sadda S, Zhuo Y, Rosenfeld MG, Zhang K. PMID: 23434931; PMCID: PMC3712060.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Epigenetic regulation of human embryonic stem cells. Front Genet. 2012; 3:238.
Hu Q, Rosenfeld MG. PMID: 23133442; PMCID: PMC3488762.
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PubMed Mentions:
12
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DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol. 2012 Nov; 19(11):1168-75.
Hu Q, Tanasa B, Trabucchi M, Li W, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 23064648; PMCID: PMC3743530.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell. 2012 Oct 12; 48(1):28-38.
Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. PMID: 22921934; PMCID: PMC3472359.
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PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proc Natl Acad Sci U S A. 2012 Sep 04; 109(36):14381-6.
Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, Héroux A, Botuyan MV, Yaffe MB, Couch FJ, Rosenfeld MG, Mer G. PMID: 22908299; PMCID: PMC3437875.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012; 8(7):e1002823.
Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M. PMID: 22844247; PMCID: PMC3405994.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell. 2012 Aug 10; 47(3):422-33.
Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. PMID: 22727668; PMCID: PMC3418396.
View in:
PubMed Mentions:
148 Fields:
Translation:
HumansCells
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A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2. Mol Cell. 2012 Apr 13; 46(1):91-104.
Cardamone MD, Krones A, Tanasa B, Taylor H, Ricci L, Ohgi KA, Glass CK, Rosenfeld MG, Perissi V. PMID: 22424771; PMCID: PMC3327812.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4609-14.
Li H, Zhou H, Wang D, Qiu J, Zhou Y, Li X, Rosenfeld MG, Ding S, Fu XD. PMID: 22396588; PMCID: PMC3311343.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Asymmetric requirement of surface epithelial β-catenin during the upper and lower jaw development. Dev Dyn. 2012 Apr; 241(4):663-74.
Sun Y, Teng I, Huo R, Rosenfeld MG, Olson LE, Li X, Li X. PMID: 22354888; PMCID: PMC3308359.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Molecular logic underlying chromosomal translocations, random or non-random? Adv Cancer Res. 2012; 113:241-79.
Lin C, Yang L, Rosenfeld MG. PMID: 22429857.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 2011 Dec; 7(12):e1002401.
Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. PMID: 22174696; PMCID: PMC3234212.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell. 2011 Nov 11; 147(4):773-88.
Yang L, Lin C, Liu W, Zhang J, Ohgi KA, Grinstein JD, Dorrestein PC, Rosenfeld MG. PMID: 22078878; PMCID: PMC3297197.
View in:
PubMed Mentions:
344 Fields:
Translation:
HumansCells
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Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS Genet. 2011 Nov; 7(11):e1002344.
Grossman TR, Gamliel A, Wessells RJ, Taghli-Lamallem O, Jepsen K, Ocorr K, Korenberg JR, Peterson KL, Rosenfeld MG, Bodmer R, Bier E. PMID: 22072978; PMCID: PMC3207880.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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A lincRNA switch for embryonic stem cell fate. Cell Res. 2011 Dec; 21(12):1646-8.
Yang L, Lin C, Rosenfeld MG. PMID: 22025254; PMCID: PMC3357988.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle. 2011 Sep 01; 10(17):3016-30.
Wang J, Geesman GJ, Hostikka SL, Atallah M, Blackwell B, Lee E, Cook PJ, Pasaniuc B, Shariat G, Halperin E, Dobke M, Rosenfeld MG, Jordan IK, Lunyak VV. PMID: 21862875; PMCID: PMC3218602.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
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SOX2 and CHD7 cooperatively regulate human disease genes. Nat Genet. 2011 Jun; 43(6):505-6.
Puc J, Rosenfeld MG. PMID: 21614087.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011 May 15; 474(7351):390-4.
Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. PMID: 21572438; PMCID: PMC3117022.
View in:
PubMed Mentions:
502 Fields:
Translation:
HumansCells
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Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes Dev. 2011 Mar 15; 25(6):594-607.
Macfarlan TS, Gifford WD, Agarwal S, Driscoll S, Lettieri K, Wang J, Andrews SE, Franco L, Rosenfeld MG, Ren B, Pfaff SL. PMID: 21357675; PMCID: PMC3059833.
View in:
PubMed Mentions:
153 Fields:
Translation:
AnimalsCells
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Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8.
Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. PMID: 21331046; PMCID: PMC3464905.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature. 2011 Feb 10; 470(7333):264-8.
Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. PMID: 21307941; PMCID: PMC3079517.
View in:
PubMed Mentions:
313 Fields:
Translation:
HumansCells
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KSRP Promotes the Maturation of a Group of miRNA Precuresors. Adv Exp Med Biol. 2011; 700:36-42.
Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. PMID: 21755471.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a003756.
Wang X, Song X, Glass CK, Rosenfeld MG. PMID: 20573714; PMCID: PMC3003465.
View in:
PubMed Mentions:
87 Fields:
Translation:
Cells
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Epigenetic control of stem cell fate to neurons and glia. Arch Pharm Res. 2010 Oct; 33(10):1467-73.
Kim HJ, Rosenfeld MG. PMID: 21052927.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12.
Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PMID: 20622854; PMCID: PMC3059551.
View in:
PubMed Mentions:
223 Fields:
Translation:
HumansCells
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Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet. 2010 Feb; 11(2):109-23.
Perissi V, Jepsen K, Glass CK, Rosenfeld MG. PMID: 20084085.
View in:
PubMed Mentions:
265 Fields:
Translation:
HumansAnimalsCells
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RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer. Mol Cell. 2010 Jan 29; 37(2):183-95.
Lee JM, Kim IS, Kim H, Lee JS, Kim K, Yim HY, Jeong J, Kim JH, Kim JY, Lee H, Seo SB, Kim H, Rosenfeld MG, Kim KI, Baek SH. PMID: 20122401.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
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KSRP promotes the maturation of a group of miRNA precursors. Adv Exp Med Biol. 2010; 700:36-42.
Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. PMID: 21627028; PMCID: PMC5705231.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation. Cell Death Differ. 2010 Jun; 17(6):975-83.
Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P. PMID: 20019746.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 2009 Dec 11; 139(6):1069-83.
Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. PMID: 19962179; PMCID: PMC2812435.
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PubMed Mentions:
310 Fields:
Translation:
HumansCells
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The biology of hormone refractory breast and prostate cancer: An NCI workshop report. Cancer Biol Ther. 2009 Nov; 8(21):1975-85.
Mohla S, Stearns V, Sathyamoorthy N, Rosenfeld MG, Nelson P. PMID: 19783900.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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How to control miRNA maturation? RNA Biol. 2009 Nov-Dec; 6(5):536-40.
Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R. PMID: 19875945.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Nuclear organization in the 3D space of the nucleus - cause or consequence? Curr Opin Genet Dev. 2009 Oct; 19(5):424-36.
Nunez E, Fu XD, Rosenfeld MG. PMID: 19846290; PMCID: PMC2796509.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Mol Cell. 2009 Jul 10; 35(1):1-10.
Zhong XY, Wang P, Han J, Rosenfeld MG, Fu XD. PMID: 19595711; PMCID: PMC2744344.
View in:
PubMed Mentions:
165 Fields:
Translation:
HumansAnimalsCells
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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell. 2009 Jul 10; 35(1):48-57.
Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. PMID: 19595715; PMCID: PMC2759189.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Transcriptional regulation through noncoding RNAs and epigenetic modifications. RNA Biol. 2009 Jul-Aug; 6(3):233-6.
Kurokawa R, Rosenfeld MG, Glass CK. PMID: 19411842.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature. 2009 Jun 18; 459(7249):1010-4.
Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. PMID: 19458619; PMCID: PMC2768332.
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PubMed Mentions:
358 Fields:
Translation:
HumansAnimalsCells
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LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J. 2009 Sep; 23(9):2898-908.
Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, Rosenfeld MG, Briata P, Gherzi R. PMID: 19423639.
View in:
PubMed Mentions:
106 Fields:
Translation:
AnimalsCells
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ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7420-5.
Cardamone MD, Bardella C, Gutierrez A, Di Croce L, Rosenfeld MG, Di Renzo MF, De Bortoli M. PMID: 19383788; PMCID: PMC2671327.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 2009 Apr 03; 137(1):47-59.
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. PMID: 19345186; PMCID: PMC2754279.
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PubMed Mentions:
460 Fields:
Translation:
AnimalsCells
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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93.
Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. PMID: 19299558; PMCID: PMC2661610.
View in:
PubMed Mentions:
140 Fields:
Translation:
AnimalsCells
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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6.
Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. PMID: 19234442; PMCID: PMC2692521.
View in:
PubMed Mentions:
279 Fields:
Translation:
HumansAnimalsCells
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Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20179-84.
Li H, Lovci MT, Kwon YS, Rosenfeld MG, Fu XD, Yeo GW. PMID: 19088194; PMCID: PMC2603435.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A. 2008 12 09; 105(49):19199-204.
Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 19052240; PMCID: PMC2593616.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansCells
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Histone H2A ubiquitination in transcriptional regulation and DNA damage repair. Int J Biochem Cell Biol. 2009 Jan; 41(1):12-5.
Zhou W, Wang X, Rosenfeld MG. PMID: 18929679.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development. 2008 Sep; 135(17):2905-16.
Jeong J, Li X, McEvilly RJ, Rosenfeld MG, Lufkin T, Rubenstein JL. PMID: 18697905; PMCID: PMC4913551.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Jul 11; 134(1):189.
Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 18630350.
View in:
PubMed Mentions:
2 Fields:
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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature. 2008 Jul 03; 454(7200):126-30.
Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG, Glass CK, Kurokawa R. PMID: 18509338; PMCID: PMC2823488.
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PubMed Mentions:
523 Fields:
Translation:
HumansCells
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Genetic approaches identify adult pituitary stem cells. Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17):6332-7.
Gleiberman AS, Michurina T, Encinas JM, Roig JL, Krasnov P, Balordi F, Fishell G, Rosenfeld MG, Enikolopov G. PMID: 18436641; PMCID: PMC2359820.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Epigenetic regulation of stem cell fate. Hum Mol Genet. 2008 Apr 15; 17(R1):R28-36.
Lunyak VV, Rosenfeld MG. PMID: 18632693.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66.
Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 18374649; PMCID: PMC2364611.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansAnimalsCells
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Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Mar 21; 132(6):996-1010.
Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 18358812.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Cooperative regulation in development by SMRT and FOXP1. Genes Dev. 2008 Mar 15; 22(6):740-5.
Jepsen K, Gleiberman AS, Shi C, Simon DI, Rosenfeld MG. PMID: 18347093; PMCID: PMC2275427.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2481-6.
Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carrière C. PMID: 18272476; PMCID: PMC2268162.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell. 2008 Jan 18; 29(1):69-80.
Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG. PMID: 18206970; PMCID: PMC2327256.
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PubMed Mentions:
185 Fields:
Translation:
HumansAnimalsCells
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Signaling and epigenetic regulation of pituitary development. Curr Opin Cell Biol. 2007 Dec; 19(6):605-11.
Zhu X, Wang J, Ju BG, Rosenfeld MG. PMID: 17988851; PMCID: PMC2796608.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15; 450(7168):415-9.
Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG. PMID: 17928865.
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PubMed Mentions:
215 Fields:
Translation:
HumansAnimalsCells
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Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet. 2007 Oct; 39(10):1225-34.
Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. PMID: 17767158; PMCID: PMC5578467.
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PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell. 2007 Aug 17; 27(4):609-21.
Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, Erdjument-Bromage H, Tempst P, Glass CK, Rosenfeld MG. PMID: 17707232; PMCID: PMC2709280.
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PubMed Mentions:
145 Fields:
Translation:
HumansAnimalsCells
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Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science. 2007 Jul 13; 317(5835):248-51.
Lunyak VV, Prefontaine GG, Núñez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, García-Díaz A, Zhu X, Yung Y, Montoliu L, Glass CK, Rosenfeld MG. PMID: 17626886.
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PubMed Mentions:
145 Fields:
Translation:
AnimalsCells
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Molecular physiology of pituitary development: signaling and transcriptional networks. Physiol Rev. 2007 Jul; 87(3):933-63.
Zhu X, Gleiberman AS, Rosenfeld MG. PMID: 17615393.
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PubMed Mentions:
138 Fields:
Translation:
AnimalsCells
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816.
ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA, NISC Comparative Sequencing Program, Baylor College of Medicine Human Genome Sequencing Center, Washington University Genome Sequencing Center, Broad Institute, Children's Hospital Oakland Research Institute, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ. PMID: 17571346; PMCID: PMC2212820.
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PubMed Mentions:
2627 Fields:
Translation:
HumansCells
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Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007 Aug; 27(15):5393-402.
Xiao R, Sun Y, Ding JH, Lin S, Rose DW, Rosenfeld MG, Fu XD, Li X. PMID: 17526736; PMCID: PMC1952092.
View in:
PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A. 2007 May 29; 104(22):9313-8.
Lin L, Cui L, Zhou W, Dufort D, Zhang X, Cai CL, Bu L, Yang L, Martin J, Kemler R, Rosenfeld MG, Chen J, Evans SM. PMID: 17519333; PMCID: PMC1890491.
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PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
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Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19; 446(7138):882-7.
Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG. PMID: 17392792.
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PubMed Mentions:
310 Fields:
Translation:
AnimalsCells
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Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):4852-7.
Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. PMID: 17360330; PMCID: PMC1821125.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518.
Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. PMID: 17289570; PMCID: PMC1994663.
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PubMed Mentions:
234 Fields:
Translation:
HumansCells
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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007 Jan 12; 25(1):57-70.
Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK. PMID: 17218271; PMCID: PMC1850387.
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PubMed Mentions:
262 Fields:
Translation:
HumansAnimalsCells
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Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Found Symp. 2007; 286:183-96; discussion 196-203.
Pascual G, Sullivan AL, Ogawa S, Gamliel A, Perissi V, Rosenfeld MG, Glass CK. PMID: 18269183.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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A breaking strategy for topoisomerase IIbeta/PARP-1-dependent regulated transcription. Cell Cycle. 2006 Nov; 5(22):2557-60.
Ju BG, Rosenfeld MG. PMID: 17106262.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 01; 20(19):2739-53.
Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG. PMID: 17015435; PMCID: PMC1578699.
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PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
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Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system. Dev Biol. 2006 Oct 15; 298(2):571-84.
Bush KT, Vaughn DA, Li X, Rosenfeld MG, Rose DW, Mendoza SA, Nigam SK. PMID: 16934795.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science. 2006 Jun 23; 312(5781):1798-802.
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG. PMID: 16794079.
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PubMed Mentions:
444 Fields:
Translation:
HumansCells
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Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 2006 Jun 01; 20(11):1405-28.
Rosenfeld MG, Lunyak VV, Glass CK. PMID: 16751179.
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PubMed Mentions:
397 Fields:
Translation:
HumansAnimalsCells
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An interview with Michael G. Rosenfeld, M.D. Assay Drug Dev Technol. 2006 Jun; 4(3):235-8.
Rosenfeld MG. PMID: 16834529.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res. 2006 Jun 01; 66(11):5565-73.
Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A. PMID: 16740691.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 05; 125(3):593-605.
Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG. PMID: 16678101.
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PubMed Mentions:
128 Fields:
Translation:
HumansAnimalsCells
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Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3100-5.
Baek SH, Ohgi KA, Nelson CA, Welsbie D, Chen C, Sawyers CL, Rose DW, Rosenfeld MG. PMID: 16492776; PMCID: PMC1413901.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell. 2006 Feb 10; 124(3):615-29.
Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H, Akira S, Kotol PF, Glass CK, Rosenfeld MG, Rose DW. PMID: 16469706.
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PubMed Mentions:
127 Fields:
Translation:
HumansAnimalsCells
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Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metab. 2006 Feb; 3(2):111-22.
Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T. PMID: 16459312.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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Expression of nestin-green fluorescent protein transgene marks oval cells in the adult liver. Dev Dyn. 2005 Oct; 234(2):413-21.
Gleiberman AS, Encinas JM, Mignone JL, Michurina T, Rosenfeld MG, Enikolopov G. PMID: 16127706; PMCID: PMC2751636.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21.
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. PMID: 16143103; PMCID: PMC1430687.
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PubMed Mentions:
259 Fields:
Translation:
AnimalsCells
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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature. 2005 Sep 29; 437(7059):759-63.
Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK. PMID: 16127449; PMCID: PMC1464798.
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PubMed Mentions:
561 Fields:
Translation:
AnimalsCells
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Controlling nuclear receptors: the circular logic of cofactor cycles. Nat Rev Mol Cell Biol. 2005 Jul; 6(7):542-54.
Perissi V, Rosenfeld MG. PMID: 15957004.
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PubMed Mentions:
200 Fields:
Translation:
HumansAnimalsCells
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Genetic control of pituitary development and hypopituitarism. Curr Opin Genet Dev. 2005 Jun; 15(3):332-40.
Zhu X, Lin CR, Prefontaine GG, Tollkuhn J, Rosenfeld MG. PMID: 15917210.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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No rest for REST: REST/NRSF regulation of neurogenesis. Cell. 2005 May 20; 121(4):499-501.
Lunyak VV, Rosenfeld MG. PMID: 15907461.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Direct isolation and identification of promoters in the human genome. Genome Res. 2005 Jun; 15(6):830-9.
Kim TH, Barrera LO, Qu C, Van Calcar S, Trinklein ND, Cooper SJ, Luna RM, Glass CK, Rosenfeld MG, Myers RM, Ren B. PMID: 15899964; PMCID: PMC1142473.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May; 132(10):2475-87.
Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S. PMID: 15843407; PMCID: PMC5576439.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature. 2005 Apr 14; 434(7035):921-6.
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. PMID: 15829968.
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PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling. Proc Natl Acad Sci U S A. 2005 Mar 08; 102(10):3708-13.
Olson LE, Zhang J, Taylor H, Rose DW, Rosenfeld MG. PMID: 15728386; PMCID: PMC553323.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005 Jan 14; 120(1):59-72.
Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J, Chen J, Xiao RP, Cheng H, Fu XD. PMID: 15652482.
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PubMed Mentions:
178 Fields:
Translation:
HumansAnimalsCells
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Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep. 2005 Jan; 6(1):77-82.
Telese F, Bruni P, Donizetti A, Gianni D, D'Ambrosio C, Scaloni A, Zambrano N, Rosenfeld MG, Russo T. PMID: 15592452; PMCID: PMC1299219.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell. 2004 Dec 17; 119(6):815-29.
Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, Rosenfeld MG. PMID: 15607978.
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PubMed Mentions:
125 Fields:
Translation:
AnimalsCells
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Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia. J Biol Chem. 2004 Dec 24; 279(52):54620-8.
Beischlag TV, Taylor RT, Rose DW, Yoon D, Chen Y, Lee WH, Rosenfeld MG, Hankinson O. PMID: 15485806.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Transcriptional control of precursor proliferation in the early phases of pituitary development. Curr Opin Genet Dev. 2004 Oct; 14(5):567-74.
Zhu X, Rosenfeld MG. PMID: 15380249.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14461-6.
Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, Rose DW, Johnson RS, Rosenfeld MG, Glass CK. PMID: 15452344; PMCID: PMC521940.
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PubMed Mentions:
105 Fields:
Translation:
AnimalsCells
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Nuclear receptor coregulators: their modification codes and regulatory mechanism by translocation. Biochem Biophys Res Commun. 2004 Jul 02; 319(3):707-14.
Baek SH, Rosenfeld MG. PMID: 15184040.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron. 2004 Jun 24; 42(6):961-72.
Korzus E, Rosenfeld MG, Mayford M. PMID: 15207240; PMCID: PMC8048715.
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PubMed Mentions:
378 Fields:
Translation:
AnimalsCells
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REST and peace for the neuronal-specific transcriptional program. Ann N Y Acad Sci. 2004 Apr; 1014:110-20.
Lunyak VV, Prefontaine GG, Rosenfeld MG. PMID: 15153425.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Hum Mol Genet. 2004 May 15; 13(10):1057-67.
Toyo-oka K, Hirotsune S, Gambello MJ, Zhou ZQ, Olson L, Rosenfeld MG, Eisenman R, Hurlin P, Wynshaw-Boris A. PMID: 15028671.
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PubMed Mentions:
26 Fields:
Translation:
Animals
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From panhypopituitarism to combined pituitary deficiencies: do we need the anterior pituitary? Rev Endocr Metab Disord. 2004 Mar; 5(1):5-13.
Carrière C, Gleiberman A, Lin CR, Rosenfeld MG. PMID: 14966385.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell. 2004 Feb 20; 116(4):511-26.
Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG. PMID: 14980219.
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PubMed Mentions:
248 Fields:
Translation:
AnimalsCells
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Transcription: origins of licensing control. Nature. 2004 Feb 19; 427(6976):687-8.
Li X, Rosenfeld MG. PMID: 14973463.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Molecular determinants of resistance to antiandrogen therapy. Nat Med. 2004 Jan; 10(1):33-9.
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. PMID: 14702632.
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PubMed Mentions:
988 Fields:
Translation:
HumansCells
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RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron. 2003 Dec 18; 40(6):1119-31.
Gold DA, Baek SH, Schork NJ, Rose DW, Larsen DD, Sachs BD, Rosenfeld MG, Hamilton BA. PMID: 14687547; PMCID: PMC2717708.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20; 426(6964):247-54.
Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. PMID: 14628042.
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PubMed Mentions:
283 Fields:
Translation:
AnimalsCells
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The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs. Mol Cell. 2003 Nov; 12(5):1201-11.
Briata P, Ilengo C, Corte G, Moroni C, Rosenfeld MG, Chen CY, Gherzi R. PMID: 14636578.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol. 2003 Aug; 23(16):5780-9.
Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK. PMID: 12897148; PMCID: PMC166346.
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PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
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Stress-mediated heart rate dynamics after deletion of the gene encoding corticotropin-releasing factor receptor 2. Eur J Neurosci. 2003 May; 17(10):2231-5.
Stiedl O, Meyer M, Kishimoto T, Rosenfeld MG, Spiess J. PMID: 12786991.
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PubMed Mentions:
6 Translation:
Animals
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Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3245-50.
Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG. PMID: 12629224; PMCID: PMC152277.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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Paired-like repression/activation in pituitary development. Recent Prog Horm Res. 2003; 58:249-61.
Olson LE, Dasen JS, Ju BG, Tollkuhn J, Rosenfeld MG. PMID: 12795422.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Evidence for vestibular regulation of autonomic functions in a mouse genetic model. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):17078-82.
Murakami DM, Erkman L, Hermanson O, Rosenfeld MG, Fuller CA. PMID: 12466504; PMCID: PMC139272.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Identification of genes that are downregulated in the absence of the POU domain transcription factor pou3f1 (Oct-6, Tst-1, SCIP) in sciatic nerve. J Neurosci. 2002 Dec 01; 22(23):10217-31.
Bermingham JR, Shumas S, Whisenhunt T, Sirkowski EE, O'Connell S, Scherer SS, Rosenfeld MG. PMID: 12451123; PMCID: PMC6758772.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell. 2002 Nov 27; 111(5):673-85.
Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG. PMID: 12464179.
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PubMed Mentions:
216 Fields:
Translation:
AnimalsCells
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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science. 2002 Nov 29; 298(5599):1747-52.
Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG. PMID: 12399542.
View in:
PubMed Mentions:
183 Fields:
Translation:
HumansAnimalsCells
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N-CoR controls differentiation of neural stem cells into astrocytes. Nature. 2002 Oct 31; 419(6910):934-9.
Hermanson O, Jepsen K, Rosenfeld MG. PMID: 12410313.
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PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
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Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell. 2002 Oct; 10(4):857-69.
Kumar V, Carlson JE, Ohgi KA, Edwards TA, Rose DW, Escalante CR, Rosenfeld MG, Aggarwal AK. PMID: 12419229.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansCells
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Signaling and transcriptional control of pituitary development. Curr Opin Genet Dev. 2002 Oct; 12(5):534-39.
Burgess R, Lunyak V, Rosenfeld M. PMID: 12200158.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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REST repression of neuronal genes requires components of the hSWI.SNF complex. J Biol Chem. 2002 Oct 25; 277(43):41038-45.
Battaglioli E, Andrés ME, Rose DW, Chenoweth JG, Rosenfeld MG, Anderson ME, Mandel G. PMID: 12192000.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 2002 Aug 16; 297(5584):1180-3.
Li X, Perissi V, Liu F, Rose DW, Rosenfeld MG. PMID: 12130660.
View in:
PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell. 2002 Jul 12; 110(1):55-67.
Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. PMID: 12150997.
View in:
PubMed Mentions:
212 Fields:
Translation:
HumansAnimalsCells
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Perspective: genetic and genomic approaches in elucidating mechanisms of pituitary development. Endocrinology. 2002 Jun; 143(6):2007-11.
Olson LE, Rosenfeld MG. PMID: 12021162.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol Cell Biol. 2002 Jun; 22(12):4319-33.
Beischlag TV, Wang S, Rose DW, Torchia J, Reisz-Porszasz S, Muhammad K, Nelson WE, Probst MR, Rosenfeld MG, Hankinson O. PMID: 12024042; PMCID: PMC133867.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansCells
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An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 2002 Apr 19; 109(2):169-80.
Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. PMID: 12007404.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Pituitary development: regulatory codes in mammalian organogenesis. Science. 2002 Mar 22; 295(5563):2231-5.
Scully KM, Rosenfeld MG. PMID: 11910101.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol Metab. 2002 Mar; 13(2):55-60.
Hermanson O, Glass CK, Rosenfeld MG. PMID: 11854019.
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PubMed Mentions:
102 Fields:
Translation:
HumansAnimalsCells
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Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22; 295(5559):1528-32.
McEvilly RJ, de Diaz MO, Schonemann MD, Hooshmand F, Rosenfeld MG. PMID: 11859196.
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PubMed Mentions:
114 Fields:
Translation:
AnimalsCells
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Biological roles and mechanistic actions of co-repressor complexes. J Cell Sci. 2002 Feb 15; 115(Pt 4):689-98.
Jepsen K, Rosenfeld MG. PMID: 11865025.
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PubMed Mentions:
140 Fields:
Translation:
HumansAnimalsCells
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Pitx genes during cardiovascular development. Cold Spring Harb Symp Quant Biol. 2002; 67:81-7.
Kioussi C, Briata P, Baek SH, Wynshaw-Boris A, Rose DW, Rosenfeld MG. PMID: 12858527.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 01; 15(23):3193-207.
Dasen JS, Martinez Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG. PMID: 11731482; PMCID: PMC312840.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
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Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem. 2001 Oct 05; 276(40):36865-8.
Rosenfeld MG, Glass CK. PMID: 11459854.
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PubMed Mentions:
122 Fields:
Translation:
HumansCells
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Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8674-9.
Liu J, Lin C, Gleiberman A, Ohgi KA, Herman T, Huang HP, Tsai MJ, Rosenfeld MG. PMID: 11447259; PMCID: PMC37494.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb; 128(3):377-86.
Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. PMID: 11152636.
View in:
PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
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POU domain factors in the neuroendocrine system: lessons from developmental biology provide insights into human disease. Endocr Rev. 2001 Feb; 22(1):2-35.
Andersen B, Rosenfeld MG. PMID: 11159814.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Signaling and transcriptional mechanisms in pituitary development. Annu Rev Neurosci. 2001; 24:327-55.
Dasen JS, Rosenfeld MG. PMID: 11283314.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13549-54.
Wang Z, Rose DW, Hermanson O, Liu F, Herman T, Wu W, Szeto D, Gleiberman A, Krones A, Pratt K, Rosenfeld R, Glass CK, Rosenfeld MG. PMID: 11087842; PMCID: PMC17613.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system. Neuron. 2000 Dec; 28(3):779-92.
Erkman L, Yates PA, McLaughlin T, McEvilly RJ, Whisenhunt T, O'Connell SM, Krones AI, Kirby MA, Rapaport DH, Bermingham JR, O'Leary DD, Rosenfeld MG. PMID: 11163266.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science. 2000 Nov 10; 290(5494):1127-31.
Scully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carrière C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG. PMID: 11073444.
View in:
PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
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Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell. 2000 Sep 15; 102(6):753-63.
Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E, Hedrick SM, Mandel G, Glass CK, Rose DW, Rosenfeld MG. PMID: 11030619.
View in:
PubMed Mentions:
196 Fields:
Translation:
AnimalsCells
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Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4363-8.
Llopis J, Westin S, Ricote M, Wang Z, Cho CY, Kurokawa R, Mullen TM, Rose DW, Rosenfeld MG, Tsien RY, Glass CK, Wang J. PMID: 10760302; PMCID: PMC18247.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. Nat Genet. 2000 Apr; 24(4):415-9.
Kishimoto T, Radulovic J, Radulovic M, Lin CR, Schrick C, Hooshmand F, Hermanson O, Rosenfeld MG, Spiess J. PMID: 10742109.
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PubMed Mentions:
140 Fields:
Translation:
AnimalsCells
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The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 2000 Jan 15; 14(2):121-41.
Glass CK, Rosenfeld MG. PMID: 10652267.
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PubMed Mentions:
650 Fields:
Translation:
HumansAnimalsCells
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Nuclear receptor coactivators. Adv Pharmacol. 2000; 47:89-112.
Westin S, Rosenfeld MG, Glass CK. PMID: 10582085.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo. Recent Prog Horm Res. 2000; 55:1-13; discussion 13-4.
Rosenfeld MG, Briata P, Dasen J, Gleiberman AS, Kioussi C, Lin C, O'Connell SM, Ryan A, Szeto DP, Treier M. PMID: 11036930.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev. 1999 Dec 15; 13(24):3198-208.
Perissi V, Staszewski LM, McInerney EM, Kurokawa R, Krones A, Rose DW, Lambert MH, Milburn MV, Glass CK, Rosenfeld MG. PMID: 10617569; PMCID: PMC317209.
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PubMed Mentions:
142 Fields:
Translation:
HumansAnimalsCells
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Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14378-82.
Kioussi C, O'Connell S, St-Onge L, Treier M, Gleiberman AS, Gruss P, Rosenfeld MG. PMID: 10588713; PMCID: PMC24444.
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PubMed Mentions:
38 Fields:
Translation:
Animals
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Signaling mechanisms in pituitary morphogenesis and cell fate determination. Curr Opin Cell Biol. 1999 Dec; 11(6):669-77.
Dasen JS, Rosenfeld MG. PMID: 10600709.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Combinatorial codes in signaling and synergy: lessons from pituitary development. Curr Opin Genet Dev. 1999 Oct; 9(5):566-74.
Dasen JS, Rosenfeld MG. PMID: 10508698.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999 Sep 16; 401(6750):279-82.
Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisúa-Belmonte JC, Rosenfeld MG. PMID: 10499586.
View in:
PubMed Mentions:
181 Fields:
Translation:
AnimalsCells
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RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. Nat Genet. 1999 Aug; 22(4):394-9.
Bach I, Rodriguez-Esteban C, Carrière C, Bhushan A, Krones A, Rose DW, Glass CK, Andersen B, Izpisúa Belmonte JC, Rosenfeld MG. PMID: 10431247.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Body's left side. Cell Mol Biol (Noisy-le-grand). 1999 Jul; 45(5):517-22.
Kioussi C, Rosenfeld MG. PMID: 10512184.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28; 97(5):587-98.
Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG. PMID: 10367888.
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PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
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Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev. 1999 Apr; 9(2):140-7.
Xu L, Glass CK, Rosenfeld MG. PMID: 10322133.
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PubMed Mentions:
239 Fields:
Translation:
Animals
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Factor-specific modulation of CREB-binding protein acetyltransferase activity. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3652-7.
Perissi V, Dasen JS, Kurokawa R, Wang Z, Korzus E, Rose DW, Glass CK, Rosenfeld MG. PMID: 10097092; PMCID: PMC22349.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis. Mech Dev. 1999 Mar; 81(1-2):23-35.
Kioussi C, Carrière C, Rosenfeld MG. PMID: 10330482.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 Feb 15; 13(4):484-94.
Szeto DP, Rodriguez-Esteban C, Ryan AK, O'Connell SM, Liu F, Kioussi C, Gleiberman AS, Izpisúa-Belmonte JC, Rosenfeld MG. PMID: 10049363; PMCID: PMC316471.
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PubMed Mentions:
122 Fields:
Translation:
Animals
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Genetically directed representational difference analysis-based positional cloning and snorthern analysis of candidate genes. Methods Enzymol. 1999; 306:67-89.
Sornson MW, Rosenfeld MG. PMID: 10432448.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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The role of POU domain proteins in the regulation of mammalian pituitary and nervous system development. Prog Nucleic Acid Res Mol Biol. 1999; 63:223-55.
McEvilly RJ, Rosenfeld MG. PMID: 10506833.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15418-23.
Sugihara TM, Bach I, Kioussi C, Rosenfeld MG, Andersen B. PMID: 9860983; PMCID: PMC28057.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 1998 Nov 01; 12(21):3357-68.
McInerney EM, Rose DW, Flynn SE, Westin S, Mullen TM, Krones A, Inostroza J, Torchia J, Nolte RT, Assa-Munt N, Milburn MV, Glass CK, Rosenfeld MG. PMID: 9808623; PMCID: PMC317227.
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PubMed Mentions:
146 Fields:
Translation:
AnimalsCells
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Signal-specific co-activator domain requirements for Pit-1 activation. Nature. 1998 Sep 17; 395(6699):301-6.
Xu L, Lavinsky RM, Dasen JS, Flynn SE, McInerney EM, Mullen TM, Heinzel T, Szeto D, Korzus E, Kurokawa R, Aggarwal AK, Rose DW, Glass CK, Rosenfeld MG. PMID: 9751061.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature. 1998 Sep 10; 395(6698):199-202.
Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, Milburn MV, Rosenfeld MG, Glass CK. PMID: 9744281.
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PubMed Mentions:
82 Fields:
Translation:
Cells
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Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature. 1998 Aug 06; 394(6693):545-51.
Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC. PMID: 9707115.
View in:
PubMed Mentions:
121 Fields:
Translation:
Animals
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Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol. 1998 Jun; 10(3):373-83.
Torchia J, Glass C, Rosenfeld MG. PMID: 9640539.
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PubMed Mentions:
130 Fields:
Translation:
AnimalsCells
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Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 1998 Jun 01; 12(11):1691-704.
Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG. PMID: 9620855; PMCID: PMC316866.
View in:
PubMed Mentions:
126 Fields:
Translation:
AnimalsCells
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Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2920-5.
Lavinsky RM, Jepsen K, Heinzel T, Torchia J, Mullen TM, Schiff R, Del-Rio AL, Ricote M, Ngo S, Gemsch J, Hilsenbeck SG, Osborne CK, Glass CK, Rosenfeld MG, Rose DW. PMID: 9501191; PMCID: PMC19670.
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PubMed Mentions:
136 Fields:
Translation:
HumansAnimalsCells
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Mutations in PROP1 cause familial combined pituitary hormone deficiency. Nat Genet. 1998 Feb; 18(2):147-9.
Wu W, Cogan JD, Pfäffle RW, Dasen JS, Frisch H, O'Connell SM, Flynn SE, Brown MR, Mullis PE, Parks JS, Phillips JA, Rosenfeld MG. PMID: 9462743.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Differential use of CREB binding protein-coactivator complexes. Science. 1998 Jan 30; 279(5351):700-3.
Kurokawa R, Kalafus D, Ogliastro MH, Kioussi C, Xu L, Torchia J, Rosenfeld MG, Glass CK. PMID: 9445474.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science. 1998 Jan 30; 279(5351):703-7.
Korzus E, Torchia J, Rose DW, Xu L, Kurokawa R, McInerney EM, Mullen TM, Glass CK, Rosenfeld MG. PMID: 9445475.
View in:
PubMed Mentions:
147 Fields:
Translation:
HumansCells
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POU domain factors in neural development. Adv Exp Med Biol. 1998; 449:39-53.
Schonemann MD, Ryan AK, Erkman L, McEvilly RJ, Bermingham J, Rosenfeld MG. PMID: 10026784.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12343-7.
Hedjran F, Yeakley JM, Huh GS, Hynes RO, Rosenfeld MG. PMID: 9356451; PMCID: PMC24936.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev. 1997 Jul 15; 11(14):1873-84.
Andersen B, Weinberg WC, Rennekampff O, McEvilly RJ, Bermingham JR, Hooshmand F, Vasilyev V, Hansbrough JF, Pittelkow MR, Yuspa SH, Rosenfeld MG. PMID: 9242494.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Reduced fertility in mice deficient for the POU protein sperm-1. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7555-60.
Pearse RV, Drolet DW, Kalla KA, Hooshmand F, Bermingham JR, Rosenfeld MG. PMID: 9207130; PMCID: PMC23860.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Characterization of Skn-1a/i POU domain factors and linkage to papillomavirus gene expression. J Biol Chem. 1997 Jun 20; 272(25):15905-13.
Andersen B, Hariri A, Pittelkow MR, Rosenfeld MG. PMID: 9188490.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature. 1997 Jun 12; 387(6634):677-84.
Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK, Rosenfeld MG. PMID: 9192892.
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PubMed Mentions:
223 Fields:
Translation:
HumansAnimalsCells
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Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Mol Endocrinol. 1997 Jun; 11(6):682-92.
Söderström M, Vo A, Heinzel T, Lavinsky RM, Yang WM, Seto E, Peterson DA, Rosenfeld MG, Glass CK. PMID: 9171232.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Role of estrogen receptor-alpha in the anterior pituitary gland. Mol Endocrinol. 1997 Jun; 11(6):674-81.
Scully KM, Gleiberman AS, Lindzey J, Lubahn DB, Korach KS, Rosenfeld MG. PMID: 9171231.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimals
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A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev. 1997 Jun 01; 11(11):1370-80.
Bach I, Carrière C, Ostendorff HP, Andersen B, Rosenfeld MG. PMID: 9192866.
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PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev. 1997 May 15; 11(10):1207-25.
Ryan AK, Rosenfeld MG. PMID: 9171367.
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PubMed Mentions:
124 Fields:
Translation:
Cells
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Mechanisms of transcriptional activation by retinoic acid receptors. Biochem Soc Trans. 1997 May; 25(2):602-5.
Glass CK, Rosenfeld MG, Rose DW, Kurokawa R, Kamei Y, Xu L, Torchia J, Ogliastro MH, Westin S. PMID: 9191164.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature. 1997 May 01; 387(6628):43-8.
Heinzel T, Lavinsky RM, Mullen TM, Söderstrom M, Laherty CD, Torchia J, Yang WM, Brard G, Ngo SD, Davie JR, Seto E, Eisenman RN, Rose DW, Glass CK, Rosenfeld MG. PMID: 9139820.
View in:
PubMed Mentions:
335 Fields:
Translation:
HumansAnimalsCells
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Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol Cell Biol. 1997 Apr; 17(4):2166-76.
DiRenzo J, Söderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Hörlein A, Rosenfeld MG, Glass CK. PMID: 9121466; PMCID: PMC232065.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Nuclear receptor coactivators. Curr Opin Cell Biol. 1997 Apr; 9(2):222-32.
Glass CK, Rose DW, Rosenfeld MG. PMID: 9069256.
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PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1074-9.
Horvai AE, Xu L, Korzus E, Brard G, Kalafus D, Mullen TM, Rose DW, Rosenfeld MG, Glass CK. PMID: 9037008; PMCID: PMC19746.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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The Pit-1 gene is regulated by distinct early and late pituitary-specific enhancers. Dev Biol. 1997 Feb 01; 182(1):180-90.
DiMattia GE, Rhodes SJ, Krones A, Carrière C, O'Connell S, Kalla K, Arias C, Sawchenko P, Rosenfeld MG. PMID: 9073460.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12; 384(6609):574-7.
McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG. PMID: 8955272.
View in:
PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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The hypothalamic-pituitary axis: co-development of two organs. Curr Opin Cell Biol. 1996 Dec; 8(6):833-43.
Treier M, Rosenfeld MG. PMID: 8939677.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 1996 Nov 28; 384(6607):327-33.
Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O'Connell SM, Gukovsky I, Carrière C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG. PMID: 8934515.
View in:
PubMed Mentions:
200 Fields:
Translation:
AnimalsCells
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A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7582-7.
Yeakley JM, Morfin JP, Rosenfeld MG, Fu XD. PMID: 8755518; PMCID: PMC38789.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7706-10.
Szeto DP, Ryan AK, O'Connell SM, Rosenfeld MG. PMID: 8755540; PMCID: PMC38811.
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PubMed Mentions:
48 Fields:
Translation:
Animals
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Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev. 1996 Jul 15; 10(14):1751-62.
Bermingham JR, Scherer SS, O'Connell S, Arroyo E, Kalla KA, Powell FL, Rosenfeld MG. PMID: 8698235.
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PubMed Mentions:
100 Fields:
Translation:
AnimalsCells
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Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature. 1996 Jun 13; 381(6583):603-6.
Erkman L, McEvilly RJ, Luo L, Ryan AK, Hooshmand F, O'Connell SM, Keithley EM, Rapaport DH, Ryan AF, Rosenfeld MG. PMID: 8637595.
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PubMed Mentions:
179 Fields:
Translation:
AnimalsCells
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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell. 1996 May 03; 85(3):403-14.
Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG. PMID: 8616895.
View in:
PubMed Mentions:
442 Fields:
Translation:
AnimalsCells
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Transcriptional control of cell phenotypes in the neuroendocrine system. Recent Prog Horm Res. 1996; 51:217-38; discussion 238-9.
Rosenfeld MG, Bach I, Erkman L, Li P, Lin C, Lin S, McEvilly R, Ryan A, Rhodes S, Schonnemann M, Scully K. PMID: 8701080.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev. 1995 Dec 15; 9(24):3122-35.
Schonemann MD, Ryan AK, McEvilly RJ, O'Connell SM, Arias CA, Kalla KA, Li P, Sawchenko PE, Rosenfeld MG. PMID: 8543156.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec; 172(2):495-503.
Andersen B, Pearse RV, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG. PMID: 8612966.
View in:
PubMed Mentions:
46 Fields:
Translation:
Animals
-
Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature. 1995 Oct 05; 377(6548):451-4.
Kurokawa R, Söderström M, Hörlein A, Halachmi S, Brown M, Rosenfeld MG, Glass CK. PMID: 7566126.
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PubMed Mentions:
130 Fields:
Translation:
HumansCells
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Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2). Genomics. 1995 Sep 01; 29(1):70-9.
Bermingham JR, Arden KC, Naumova AK, Sapienza C, Viars CS, Fu XD, Khotz J, Manley JL, Rosenfeld MG. PMID: 8530103.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev. 1995 Aug 15; 9(16):1992-2006.
Holloway JM, Szeto DP, Scully KM, Glass CK, Rosenfeld MG. PMID: 7649480.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2720-4.
Bach I, Rhodes SJ, Pearse RV, Heinzel T, Gloss B, Scully KM, Sawchenko PE, Rosenfeld MG. PMID: 7708713; PMCID: PMC42290.
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PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle. Proc Natl Acad Sci U S A. 1995 Feb 14; 92(4):1108-12.
Kishimoto T, Pearse RV, Lin CR, Rosenfeld MG. PMID: 7755719; PMCID: PMC42647.
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PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis. J Biol Chem. 1994 Nov 25; 269(47):29335-8.
Andersen B, Rosenfeld MG. PMID: 7961905.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature. 1994 Oct 06; 371(6497):528-31.
Kurokawa R, DiRenzo J, Boehm M, Sugarman J, Gloss B, Rosenfeld MG, Heyman RA, Glass CK. PMID: 7935766.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansCells
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Transcriptional mechanisms in anterior pituitary cell differentiation. Curr Opin Genet Dev. 1994 Oct; 4(5):709-17.
Rhodes SJ, DiMattia GE, Rosenfeld MG. PMID: 7849511.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope. Development. 1994 Mar; 120(3):515-22.
Lin SC, Li S, Drolet DW, Rosenfeld MG. PMID: 8162852.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron. 1994 Jan; 12(1):205-18.
Turner EE, Jenne KJ, Rosenfeld MG. PMID: 7904822.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. Neuron. 1993 Dec; 11(6):1187-95.
Chang CP, Pearse RV, O'Connell S, Rosenfeld MG. PMID: 8274282.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Genes Dev. 1993 Dec; 7(12B):2483-96.
Li P, He X, Gerrero MR, Mok M, Aggarwal A, Rosenfeld MG. PMID: 8276233.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain. Mol Endocrinol. 1993 Dec; 7(12):1551-60.
Voss JW, Wilson L, Rhodes SJ, Rosenfeld MG. PMID: 8145762.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell. Proc Natl Acad Sci U S A. 1993 Dec 01; 90(23):11084-8.
Andersen B, Pearse RV, Schlegel PN, Cichon Z, Schonemann MD, Bardin CW, Rosenfeld MG. PMID: 7902581; PMCID: PMC47926.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Immunohistochemical expression of Pit-1 protein in human pituitary adenomas. Endocr Pathol. 1993 Dec; 4(4):201-204.
Inada K, Oda K, Utsunomiya H, Sanno N, Itoh J, Osamura RY, Voss JW, Rosenfeld MG. PMID: 32138434.
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PubMed Mentions: Fields:
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Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10841-5.
Gerrero MR, McEvilly RJ, Turner E, Lin CR, O'Connell S, Jenne KJ, Hobbs MV, Rosenfeld MG. PMID: 8248179; PMCID: PMC47874.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. J Biol Chem. 1993 Nov 05; 268(31):23390-8.
Andersen B, Schonemann MD, Pearse RV, Jenne K, Sugarman J, Rosenfeld MG. PMID: 7901208.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Mol Cell Biol. 1993 Oct; 13(10):5999-6011.
Yeakley JM, Hedjran F, Morfin JP, Merillat N, Rosenfeld MG, Emeson RB. PMID: 8413203; PMCID: PMC364659.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem. 1993 Sep 15; 268(26):19312-20.
Chang CP, Lazar CS, Walsh BJ, Komuro M, Collawn JF, Kuhn LA, Tainer JA, Trowbridge IS, Farquhar MG, Rosenfeld MG, et al. PMID: 8396132.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. Genes Dev. 1993 Sep; 7(9):1674-87.
Lipkin SM, Näär AM, Kalla KA, Sack RA, Rosenfeld MG. PMID: 8370519.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature. 1993 Jul 15; 364(6434):208-13.
Lin SC, Lin CR, Gukovsky I, Lusis AJ, Sawchenko PE, Rosenfeld MG. PMID: 8391647.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
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Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev. 1993 Jul; 7(7B):1423-35.
Kurokawa R, Yu VC, Näär A, Kyakumoto S, Han Z, Silverman S, Rosenfeld MG, Glass CK. PMID: 8392479.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene. Genes Dev. 1993 Jun; 7(6):913-32.
Rhodes SJ, Chen R, DiMattia GE, Scully KM, Kalla KA, Lin SC, Yu VC, Rosenfeld MG. PMID: 8504933.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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POU-domain proteins: structure and function of developmental regulators. Curr Opin Cell Biol. 1993 Jun; 5(3):488-98.
Wegner M, Drolet DW, Rosenfeld MG. PMID: 8352967.
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PubMed Mentions:
61 Fields:
Translation:
HumansAnimals
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Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4743-7.
Wegner M, Drolet DW, Rosenfeld MG. PMID: 8389455; PMCID: PMC46589.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Synergistic interactions between Pit-1 and other elements are required for effective somatotroph rat growth hormone gene expression in transgenic mice. Mol Endocrinol. 1993 May; 7(5):694-701.
Lira SA, Kalla KA, Glass CK, Drolet DW, Rosenfeld MG. PMID: 8316253.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis. Science. 1993 Apr 02; 260(5104):78-82.
Andersen B, Schonemann MD, Flynn SE, Pearse RV, Singh H, Rosenfeld MG. PMID: 7682011.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth. Nature. 1992 Dec 24-31; 360(6406):765-8.
Lin C, Lin SC, Chang CP, Rosenfeld MG. PMID: 1334535.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Transcriptional regulation by the nuclear receptor superfamily. Curr Opin Biotechnol. 1992 Dec; 3(6):597-602.
Yu VC, Näär AM, Rosenfeld MG. PMID: 1369415.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Anterior pituitary development: short tales from dwarf mice. Cell. 1992 Aug 21; 70(4):527-30.
Voss JW, Rosenfeld MG. PMID: 1505020.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Development of Prolactin and Growth Hormone Production in the Fetal Rat Pituitary: An Immunochemical Study: (hormone production/ontogeny/fetal rat pituitary/immunochemistry). Dev Growth Differ. 1992 Aug; 34(4):473-478.
Nagata S, Rosenfeld MG, Inoue K. PMID: 37281039.
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PubMed Mentions:
1 Fields:
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A tissue-specific small nuclear ribonucleoprotein and the regulated splicing of the calcitonin/calcitonin gene-related protein transcript. J Biol Chem. 1992 Jul 25; 267(21):14573-9.
Delsert CD, Rosenfeld MG. PMID: 1386079.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 1992 Jul; 11(7):2551-61.
Mathis JM, Simmons DM, He X, Swanson LW, Rosenfeld MG. PMID: 1628619; PMCID: PMC556730.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Calcitonin gene-related peptide: a neuropeptide generated as a consequence of tissue-specific, developmentally regulated alternative RNA processing events. Ann N Y Acad Sci. 1992 Jun 30; 657:1-17.
Rosenfeld MG, Emeson RB, Yeakley JM, Merillat N, Hedjran F, Lenz J, Delsert C. PMID: 1637077.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta. Science. 1992 Apr 17; 256(5055):370-3.
Wegner M, Cao Z, Rosenfeld MG. PMID: 1314426.
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PubMed Mentions:
91 Fields:
Translation:
Cells
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A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1209-13.
Lipkin SM, Nelson CA, Glass CK, Rosenfeld MG. PMID: 1311087; PMCID: PMC48418.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription. Cell. 1992 Feb 07; 68(3):491-505.
Treacy MN, Neilson LI, Turner EE, He X, Rosenfeld MG. PMID: 1346754.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Regulation of gene expression by thyroid hormones and retinoic acid. Genet Eng (N Y). 1992; 14:185-209.
Lipkin SM, Rosenfeld MG, Glass CK. PMID: 1369379.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Expression of a family of POU-domain protein regulatory genes during development of the central nervous system. Annu Rev Neurosci. 1992; 15:139-65.
Treacy MN, Rosenfeld MG. PMID: 1575440.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell. 1991 Dec 20; 67(6):1251-66.
Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Näär AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG. PMID: 1662118.
View in:
PubMed Mentions:
280 Fields:
Translation:
AnimalsCells
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Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor. J Biol Chem. 1991 Dec 05; 266(34):23467-70.
Chang CP, Kao JP, Lazar CS, Walsh BJ, Wells A, Wiley HS, Gill GN, Rosenfeld MG. PMID: 1744139.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. Genes Dev. 1991 Oct; 5(10):1739-53.
Drolet DW, Scully KM, Simmons DM, Wegner M, Chu KT, Swanson LW, Rosenfeld MG. PMID: 1916262.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements. Science. 1991 Aug 16; 253(5021):786-9.
Kapiloff MS, Farkash Y, Wegner M, Rosenfeld MG. PMID: 1652153.
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PubMed Mentions:
38 Fields:
Translation:
Cells
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A negative feedback loop attenuates EGF-induced morphological changes. J Cell Biol. 1991 Aug; 114(3):533-43.
Welsh JB, Gill GN, Rosenfeld MG, Wells A. PMID: 1860884; PMCID: PMC2289101.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of complex transcriptional regulation: implications for brain development. Neuron. 1991 Aug; 7(2):183-96.
He X, Rosenfeld MG. PMID: 1873026.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Alternative translation initiation site usage results in two structurally distinct forms of Pit-1. J Biol Chem. 1991 Jul 15; 266(20):12832-5.
Voss JW, Yao TP, Rosenfeld MG. PMID: 2071572.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 1991 Jul; 5(7):1309-20.
Voss JW, Wilson L, Rosenfeld MG. PMID: 2065979.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell. 1991 Jun 28; 65(7):1267-79.
Näär AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG. PMID: 1648451.
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PubMed Mentions:
154 Fields:
Translation:
HumansAnimalsCells
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POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev. 1991 Jun; 5(6):897-907.
Rosenfeld MG. PMID: 2044958.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Wocko, a neurological mutant generated in a transgenic mouse pedigree. J Neurosci. 1991 Jun; 11(6):1524-30.
Crenshaw EB, Ryan A, Dillon SR, Kalla K, Rosenfeld MG. PMID: 1646293; PMCID: PMC6575413.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Calcium/calmodulin-dependent protein kinase mediates a pathway for transcriptional regulation. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3710-4.
Kapiloff MS, Mathis JM, Nelson CA, Lin CR, Rosenfeld MG. PMID: 1850836; PMCID: PMC51522.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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I-POU: a POU-domain protein that inhibits neuron-specific gene activation. Nature. 1991 Apr 18; 350(6319):577-84.
Treacy MN, He X, Rosenfeld MG. PMID: 1673230.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Structural analysis of the transmembrane domain of the epidermal growth factor receptor. J Biol Chem. 1991 Mar 25; 266(9):5750-5.
Carpenter CD, Ingraham HA, Cochet C, Walton GM, Lazar CS, Sowadski JM, Rosenfeld MG, Gill GN. PMID: 2005111.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. Mol Cell Biol. 1991 Mar; 11(3):1739-44.
He X, Gerrero R, Simmons DM, Park RE, Lin CJ, Swanson LW, Rosenfeld MG. PMID: 1705013; PMCID: PMC369487.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor. Cell. 1990 Nov 16; 63(4):729-38.
Glass CK, Devary OV, Rosenfeld MG. PMID: 2171781.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 1990 Oct 11; 347(6293):528-33.
Li S, Crenshaw EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG. PMID: 1977085.
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PubMed Mentions:
270 Fields:
Translation:
AnimalsCells
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The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):8160-4.
Holloway JM, Glass CK, Adler S, Nelson CA, Rosenfeld MG. PMID: 2236029; PMCID: PMC54912.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell. 1990 Jun 15; 61(6):1021-33.
Ingraham HA, Flynn SE, Voss JW, Albert VR, Kapiloff MS, Wilson L, Rosenfeld MG. PMID: 2350782.
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PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
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Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev. 1990 May; 4(5):695-711.
Simmons DM, Voss JW, Ingraham HA, Holloway JM, Broide RS, Rosenfeld MG, Swanson LW. PMID: 2379827.
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PubMed Mentions:
117 Fields:
Translation:
AnimalsCells
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Hormonally inducible phosphorylation of a nuclear pool of ribosomal protein S6. J Biol Chem. 1990 Mar 15; 265(8):4321-5.
Franco R, Rosenfeld MG. PMID: 2106518.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science. 1990 Feb 23; 247(4945):962-4.
Wells A, Welsh JB, Lazar CS, Wiley HS, Gill GN, Rosenfeld MG. PMID: 2305263.
View in:
PubMed Mentions:
107 Fields:
Translation:
Cells
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Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. J Biol Chem. 1990 Jan 25; 265(3):1750-4.
Walton GM, Chen WS, Rosenfeld MG, Gill GN. PMID: 1688559.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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A two-base change in a POU factor-binding site switches pituitary-specific to lymphoid-specific gene expression. Genes Dev. 1990 Jan; 4(1):43-51.
Elsholtz HP, Albert VR, Treacy MN, Rosenfeld MG. PMID: 2307370.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9778-82.
Li S, Klein ES, Russo AF, Simmons DM, Rosenfeld MG. PMID: 2532363; PMCID: PMC298585.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell. 1989 Nov 17; 59(4):697-708.
Glass CK, Lipkin SM, Devary OV, Rosenfeld MG. PMID: 2555064.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell. 1989 Oct 06; 59(1):33-43.
Chen WS, Lazar CS, Lund KA, Welsh JB, Chang CP, Walton GM, Der CJ, Wiley HS, Gill GN, Rosenfeld MG. PMID: 2790960.
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PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature. 1989 Sep 07; 341(6237):76-80.
Emeson RB, Hedjran F, Yeakley JM, Guise JW, Rosenfeld MG. PMID: 2788825.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature. 1989 Jul 06; 340(6228):35-41.
He X, Treacy MN, Simmons DM, Ingraham HA, Swanson LW, Rosenfeld MG. PMID: 2739723.
View in:
PubMed Mentions:
207 Fields:
Translation:
HumansAnimalsCells
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A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally. Genes Dev. 1989 Jul; 3(7):946-58.
Mangalam HJ, Albert VR, Ingraham HA, Kapiloff M, Wilson L, Nelson C, Elsholtz H, Rosenfeld MG. PMID: 2550324.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements. Genes Dev. 1989 Jul; 3(7):959-72.
Crenshaw EB, Kalla K, Simmons DM, Swanson LW, Rosenfeld MG. PMID: 2777076.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell. 1988 Nov 04; 55(3):519-29.
Ingraham HA, Chen RP, Mangalam HJ, Elsholtz HP, Flynn SE, Lin CR, Simmons DM, Swanson L, Rosenfeld MG. PMID: 2902928.
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199 Fields:
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AnimalsCells
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Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79. Proc Natl Acad Sci U S A. 1988 Aug; 85(16):6017-21.
Lee EY, Bookstein R, Young LJ, Lin CJ, Rosenfeld MG, Lee WH. PMID: 3413073; PMCID: PMC281896.
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14 Fields:
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Cells
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The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell. 1988 Jul 29; 54(3):313-23.
Glass CK, Holloway JM, Devary OV, Rosenfeld MG. PMID: 3396073.
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155 Fields:
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Identification of rat growth hormone genomic sequences targeting pituitary expression in transgenic mice. Proc Natl Acad Sci U S A. 1988 Jul; 85(13):4755-9.
Lira SA, Crenshaw EB, Glass CK, Swanson LW, Rosenfeld MG. PMID: 3387436; PMCID: PMC280514.
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16 Fields:
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HumansAnimalsCells
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Neuronal expression of chimeric genes in transgenic mice. Neuron. 1988 Jun; 1(4):311-20.
Russo AF, Crenshaw EB, Lira SA, Simmons DM, Swanson LW, Rosenfeld MG. PMID: 3078520.
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14 Fields:
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AnimalsCells
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Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor. Science. 1988 Mar 18; 239(4846):1400-5.
Nelson C, Albert VR, Elsholtz HP, Lu LI, Rosenfeld MG. PMID: 2831625.
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92 Fields:
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AnimalsCells
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Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain. Cell. 1988 Mar 11; 52(5):685-95.
Adler S, Waterman ML, He X, Rosenfeld MG. PMID: 3345568.
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51 Fields:
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Differential regulation of the coexpressed calcitonin/alpha-CGRP and beta-CGRP neuroendocrine genes. J Biol Chem. 1988 Jan 05; 263(1):5-8.
Russo AF, Nelson C, Roos BA, Rosenfeld MG. PMID: 3257211.
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9 Fields:
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HumansCells
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Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:545-56.
Rosenfeld MG, Glass CK, Adler S, Crenshaw EB, He X, Lira SA, Elsholtz HP, Mangalam HJ, Holloway JM, Nelson C, et al. PMID: 3254780.
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PubMed Mentions:
2 Fields:
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AnimalsCells
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Analysis of functional domains in the epidermal growth factor receptor using site-directed mutagenesis. Adv Exp Med Biol. 1988; 234:91-103.
Gill GN, Rosenfeld MG, Chen WS, Bertics PJ, Lazar CS. PMID: 3063092.
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Transgenic mice: applications to the study of the nervous system. Annu Rev Neurosci. 1988; 11:353-72.
Rosenfeld MG, Crenshaw EB, Lira SA, Swanson L, Borrelli E, Heyman R, Evans RM. PMID: 3284446.
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9 Fields:
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HumansAnimalsCells
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Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:467-76.
Gill GN, Chen WS, Lazar CS, Glenney JR, Wiley HS, Ingraham HA, Rosenfeld MG. PMID: 3254778.
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1 Fields:
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AnimalsCells
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A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature. 1987 Oct 22-28; 329(6141):738-41.
Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG. PMID: 3313046.
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71 Fields:
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AnimalsCells