Loading...

Michael Rosenfeld

Title(s)Adjunct Professor, Molecular Biology
SchoolHealth Sciences
Phone858-534-5858
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    The Enhancer Code of AD-A Genetic Approach
    NIH/NIA R01AG056511Aug 1, 2018 - Mar 31, 2023
    Role: Co-Principal Investigator
    Combinatorial Actions of Genetic Variants and Gender Bias of Alzherimer's Disease
    NIH/NIA R01AG057706Sep 30, 2017 - May 31, 2022
    Role: Principal Investigator
    Repressive Transcriptional Programs in Breast Cancer
    NIH/NCI R01CA213371Dec 13, 2016 - Nov 30, 2021
    Role: Principal Investigator
    Chromosomal Boundary Alterations Driving Transcriptional Dysregulation in Brain Disorders
    NIH/NINDS R01NS093066Jun 1, 2016 - May 31, 2021
    Role: Principal Investigator
    Gene Networks controlling macrophage-adipocyte interactions in insulin
    NIH/NIDDK P01DK074868Apr 1, 2006 - Apr 30, 2017
    Role: Co-Investigator
    Genome-wide location analysis of neuronal genes
    NIH/NINDS R01NS048243Sep 15, 2005 - May 31, 2008
    Role: Principal Investigator
    Repressors in Prostate Cancer
    NIH/NCI R01CA097134Sep 3, 2002 - Nov 30, 2013
    Role: Principal Investigator
    Genomic and Epigenetic Approaches to Cardiovascular Development and Disease
    NIH/NHLBI R01HL065445Jul 1, 2000 - Nov 30, 2014
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    Ligand Regulated Epigenetic/Nuclear Architectural Strategies and Human Disease
    NIH/NINDS R01NS034934Aug 1, 1990 - Feb 28, 2014
    Role: Principal Investigator
    BRAIN SPECIFIC FACTORS IN DEVELOPMENT AND DISEASE
    NIH/NIMH R01MH047137Aug 1, 1990 - Jul 31, 1995
    Role: Principal Investigator
    Molecular Biological Approaches to Endocrinology
    NIH/NIDDK T32DK007541Dec 20, 1986 - May 31, 2023
    Role: Principal Investigator
    Genomic and Translational Approaches to Neuroendocrine Switching Events
    NIH/NIDDK R37DK039949Aug 1, 1982 - Nov 30, 2020
    Role: Principal Investigator
    REGULATION OF NEUROENDOCRINE SWITCHING EVENTS
    NIH/NIDDK R01DK039949Aug 1, 1982 - Nov 30, 2000
    Role: Principal Investigator
    NEUROENDOCRINE PEPTIDE SWITCHING EVENTS IN CANCER
    NIH/NCI R01CA033030Aug 1, 1982 - Jun 30, 1987
    Role: Principal Investigator
    Enhancer Connectomes in Regulation of Gene Expression
    NIH/NIDDK R01DK018477Jun 1, 1977 - Dec 31, 2021
    Role: Principal Investigator
    HORMONAL AND CAMP REGULATION OF PROTEIN SYNTHESIS
    NIH/NIADDK R01AM018477Jun 1, 1977 - May 31, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Nair SJ, Yang L, Meluzzi D, Oh S, Yang F, Friedman MJ, Wang S, Suter T, Alshareedah I, Gamliel A, Ma Q, Zhang J, Hu Y, Tan Y, Ohgi KA, Jayani RS, Banerjee PR, Aggarwal AK, Rosenfeld MG. Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly. Nat Struct Mol Biol. 2019 Mar; 26(3):193-203. PMID: 30833784.
      View in: PubMed
    2. Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus. Mol Cell. 2018 09 06; 71(5):872. PMID: 30193100.
      View in: PubMed
    3. Tan Y, Jin C, Ma W, Hu Y, Tanasa B, Oh S, Gamliel A, Ma Q, Yao L, Zhang J, Ohgi K, Liu W, Aggarwal AK, Rosenfeld MG. Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program. Mol Cell. 2018 08 16; 71(4):526-539.e8. PMID: 30118678.
      View in: PubMed
    4. Kim HS, Tan Y, Ma W, Merkurjev D, Destici E, Ma Q, Suter T, Ohgi K, Friedman M, Skowronska-Krawczyk D, Rosenfeld MG. Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells. Nature. 2018 04; 556(7702):510-514. PMID: 29670286.
      View in: PubMed
    5. Gao WW, Xiao RQ, Zhang WJ, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W. JMJD6 Licenses ERa-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex. Mol Cell. 2018 04 19; 70(2):340-357.e8. PMID: 29628309.
      View in: PubMed
    6. Cardamone MD, Tanasa B, Cederquist CT, Huang J, Mahdaviani K, Li W, Rosenfeld MG, Liesa M, Perissi V. Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Mol Cell. 2018 03 01; 69(5):757-772.e7. PMID: 29499132.
      View in: PubMed
    7. Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, Glass CK, Rosenfeld MG. Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E244-E252. PMID: 29263096.
      View in: PubMed
    8. Glasgow SM, Carlson JC, Zhu W, Chaboub LS, Kang P, Lee HK, Clovis YM, Lozzi BE, McEvilly RJ, Rosenfeld MG, Creighton CJ, Lee SK, Mohila CA, Deneen B. Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis. Nat Neurosci. 2017 Nov; 20(11):1520-1528. PMID: 28892058.
      View in: PubMed
    9. Gao X, Lee HY, Li W, Platt RJ, Barrasa MI, Ma Q, Elmes RR, Rosenfeld MG, Lodish HF. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10107-10112. PMID: 28864529.
      View in: PubMed
    10. Puc J, Aggarwal AK, Rosenfeld MG. Physiological functions of programmed DNA breaks in signal-induced transcription. Nat Rev Mol Cell Biol. 2017 08; 18(8):471-476. PMID: 28537575.
      View in: PubMed
    11. Yang F, Ma Q, Liu Z, Li W, Tan Y, Jin C, Ma W, Hu Y, Shen J, Ohgi KA, Telese F, Liu W, Rosenfeld MG. Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERa-Regulated Transcriptional Program. Mol Cell. 2017 May 04; 66(3):321-331.e6. PMID: 28475868.
      View in: PubMed
    12. Füllgrabe J, Lynch-Day MA, Heldring N, Li W, Struijk RB, Ma Q, Hermanson O, Rosenfeld MG, Klionsky DJ, Joseph B. Corrigendum: The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature. 2017 03 30; 543(7647):742. PMID: 28297710.
      View in: PubMed
    13. Cucchiara V, Yang JC, Mirone V, Gao AC, Rosenfeld MG, Evans CP. Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. Cancers (Basel). 2017 Jan 16; 9(1). PMID: 28275218.
      View in: PubMed
    14. Monaghan CE, Nechiporuk T, Jeng S, McWeeney SK, Wang J, Rosenfeld MG, Mandel G. REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E406-E415. PMID: 28049845.
      View in: PubMed
    15. Scully KM, Skowronska-Krawczyk D, Krawczyk M, Merkurjev D, Taylor H, Livolsi A, Tollkuhn J, Stan RV, Rosenfeld MG. Epithelial cell integrin ß1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13408-13413. PMID: 27810956.
      View in: PubMed
    16. Chen L, Liu Z, Zhou B, Wei C, Zhou Y, Rosenfeld MG, Fu XD, Chisholm AD, Jin Y. CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins. Elife. 2016 06 02; 5. PMID: 27253061; PMCID: PMC4946901.
    17. Li W, Notani D, Rosenfeld MG. Enhancers as non-coding RNA transcription units: recent insights and future perspectives. Nat Rev Genet. 2016 Apr; 17(4):207-23. PMID: 26948815.
      View in: PubMed
    18. Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7). PMID: 26823525.
      View in: PubMed
    19. Zhu X, Tollkuhn J, Taylor H, Rosenfeld MG. Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland. Stem Cell Reports. 2015 Dec 08; 5(6):1196-1209. PMID: 26651607; PMCID: PMC4682291.
    20. Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, Wen C, Krupa M, Luo H, Ouyang H, Lin D, Wang W, Li G, Xu Y, Li O, Chung C, Yeh E, Jafari M, Ai M, Zhong Z, Shi W, Zheng L, Krawczyk M, Chen D, Shi C, Zin C, Zhu J, Mellon PL, Gao W, Abagyan R, Zhang L, Sun X, Zhong S, Zhuo Y, Rosenfeld MG, Liu Y, Zhang K. P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. Mol Cell. 2015 Sep 17; 59(6):931-40. PMID: 26365380.
      View in: PubMed
    21. Wang J, Telese F, Tan Y, Li W, Jin C, He X, Basnet H, Ma Q, Merkurjev D, Zhu X, Liu Z, Zhang J, Ohgi K, Taylor H, White RR, Tazearslan C, Suh Y, Macfarlan TS, Pfaff SL, Rosenfeld MG. LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control. Nat Neurosci. 2015 Sep; 18(9):1256-64. PMID: 26214369; PMCID: PMC4625987.
    22. Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, Zhou X, Liu Z, Tanasa B, He X, Chen AY, Ohgi K, Zhang J, Liu W, Rosenfeld MG. Condensin I and II Complexes License Full Estrogen Receptor a-Dependent Enhancer Activation. Mol Cell. 2015 Jul 16; 59(2):188-202. PMID: 26166704.
      View in: PubMed
    23. Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W. Arginine methylation of HSP70 regulates retinoid acid-mediated RARß2 gene activation. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3327-36. PMID: 26080448; PMCID: PMC4491752.
    24. Telese F, Ma Q, Perez PM, Notani D, Oh S, Li W, Comoletti D, Ohgi KA, Taylor H, Rosenfeld MG. LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron. 2015 May 06; 86(3):696-710. PMID: 25892301; PMCID: PMC4486257.
    25. Lee JY, Skon CN, Lee YJ, Oh S, Taylor JJ, Malhotra D, Jenkins MK, Rosenfeld MG, Hogquist KA, Jameson SC. The transcription factor KLF2 restrains CD4? T follicular helper cell differentiation. Immunity. 2015 Feb 17; 42(2):252-264. PMID: 25692701.
      View in: PubMed
    26. Ryu S, Teles F, Minopoli G, Russo T, Rosenfeld MG, Suh Y. An epigenomic role of Fe65 in the cellular response to DNA damage. Mutat Res. 2015 Jun; 776:40-7. PMID: 26255939; PMCID: PMC4531264.
    27. Puc J, Kozbial P, Li W, Tan Y, Liu Z, Suter T, Ohgi KA, Zhang J, Aggarwal AK, Rosenfeld MG. Ligand-dependent enhancer activation regulated by topoisomerase-I activity. Cell. 2015 Jan 29; 160(3):367-80. PMID: 25619691.
      View in: PubMed
    28. Zhang F, Tanasa B, Merkurjev D, Lin C, Song X, Li W, Tan Y, Liu Z, Zhang J, Ohgi KA, Krones A, Skowronska-Krawczyk D, Rosenfeld MG. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1380-5. PMID: 25605944; PMCID: PMC4321301.
    29. Skowronska-Krawczyk D, Rosenfeld MG. Nuclear matrix revisited? Cell Cycle. 2015; 14(10):1487-8. PMID: 25928579; PMCID: PMC4615149.
    30. Liu Z, Merkurjev D, Yang F, Li W, Oh S, Friedman MJ, Song X, Zhang F, Ma Q, Ohgi KA, Krones A, Rosenfeld MG. Enhancer activation requires trans-recruitment of a mega transcription factor complex. Cell. 2014 Oct 09; 159(2):358-73. PMID: 25303530; PMCID: PMC4465761.
    31. Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014 Dec 11; 516(7530):267-71. PMID: 25252977; PMCID: PMC4461219.
    32. Castelo-Branco G, Lilja T, Wallenborg K, Falcão AM, Marques SC, Gracias A, Solum D, Paap R, Walfridsson J, Teixeira AI, Rosenfeld MG, Jepsen K, Hermanson O. Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases. Stem Cell Reports. 2014 Sep 09; 3(3):502-15. PMID: 25241747; PMCID: PMC4266002.
    33. Skowronska-Krawczyk D, Ma Q, Schwartz M, Scully K, Li W, Liu Z, Taylor H, Tollkuhn J, Ohgi KA, Notani D, Kohwi Y, Kohwi-Shigematsu T, Rosenfeld MG. Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature. 2014 Oct 09; 514(7521):257-61. PMID: 25119036; PMCID: PMC4358797.
    34. Dias JM, Ilkhanizadeh S, Karaca E, Duckworth JK, Lundin V, Rosenfeld MG, Ericson J, Hermanson O, Teixeira AI. CtBPs sense microenvironmental oxygen levels to regulate neural stem cell state. Cell Rep. 2014 Aug 07; 8(3):665-70. PMID: 25088415.
      View in: PubMed
    35. Shenhar G, Radomislensky I, Rosenfeld M, Peleg K. Willingness of international delegations to be deployed to areas with high risk of radiation. Prehosp Disaster Med. 2014 Aug; 29(4):369-73. PMID: 25007172.
      View in: PubMed
    36. Cardamone MD, Tanasa B, Chan M, Cederquist CT, Andricovich J, Rosenfeld MG, Perissi V. GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPAR?. Cell Rep. 2014 Jul 10; 8(1):163-76. PMID: 24953653; PMCID: PMC4104678.
    37. Jin C, Yang L, Xie M, Lin C, Merkurjev D, Yang JC, Tanasa B, Oh S, Zhang J, Ohgi KA, Zhou H, Li W, Evans CP, Ding S, Rosenfeld MG. Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9235-40. PMID: 24928520; PMCID: PMC4078819.
    38. Lam MT, Li W, Rosenfeld MG, Glass CK. Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82. PMID: 24674738; PMCID: PMC4266492.
    39. Liu Z, Hu Q, Rosenfeld MG. Complexity of the RAR-mediated transcriptional regulatory programs. Subcell Biochem. 2014; 70:203-25. PMID: 24962887.
      View in: PubMed
    40. Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, Aggarwal A, Rosenfeld MG. Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell. 2013 Dec 19; 155(7):1581-1595. PMID: 24360279; PMCID: PMC3886918.
    41. Yang L, Lin C, Jin C, Yang JC, Tanasa B, Li W, Merkurjev D, Ohgi KA, Meng D, Zhang J, Evans CP, Rosenfeld MG. lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs. Nature. 2013 Aug 29; 500(7464):598-602. PMID: 23945587; PMCID: PMC4034386.
    42. Füllgrabe J, Lynch-Day MA, Heldring N, Li W, Struijk RB, Ma Q, Hermanson O, Rosenfeld MG, Klionsky DJ, Joseph B. The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature. 2013 Aug 22; 500(7463):468-71. PMID: 23863932; PMCID: PMC4006103.
    43. Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5. PMID: 23728303; PMCID: PMC3839578.
    44. Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim HS, Glass CK, Rosenfeld MG. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 2013 Jun 27; 498(7455):516-20. PMID: 23728302; PMCID: PMC3718886.
    45. Scafoglio C, Smolka M, Zhou H, Perissi V, Rosenfeld MG. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. PLoS One. 2013; 8(5):e59986. PMID: 23690919; PMCID: PMC3656868.
    46. Luo J, Zhao L, Chen AY, Zhang X, Zhu J, Zhao J, Ouyang H, Luo H, Song Y, Lee J, Patel SH, Shaw PX, Sadda S, Zhuo Y, Rosenfeld MG, Zhang K. TCF7L2 variation and proliferative diabetic retinopathy. Diabetes. 2013 Jul; 62(7):2613-7. PMID: 23434931; PMCID: PMC3712060.
    47. Telese F, Gamliel A, Skowronska-Krawczyk D, Garcia-Bassets I, Rosenfeld MG. "Seq-ing" insights into the epigenetics of neuronal gene regulation. Neuron. 2013 Feb 20; 77(4):606-23. PMID: 23439116; PMCID: PMC3736682.
    48. Hu Q, Rosenfeld MG. Epigenetic regulation of human embryonic stem cells. Front Genet. 2012; 3:238. PMID: 23133442; PMCID: PMC3488762.
    49. Hu Q, Tanasa B, Trabucchi M, Li W, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol. 2012 Nov; 19(11):1168-75. PMID: 23064648; PMCID: PMC3743530.
    50. Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell. 2012 Oct 12; 48(1):28-38. PMID: 22921934; PMCID: PMC3472359.
    51. Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, Héroux A, Botuyan MV, Yaffe MB, Couch FJ, Rosenfeld MG, Mer G. Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proc Natl Acad Sci U S A. 2012 Sep 04; 109(36):14381-6. PMID: 22908299; PMCID: PMC3437875.
    52. Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M. Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012; 8(7):e1002823. PMID: 22844247; PMCID: PMC3405994.
    53. Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA, Rosenfeld MG, Fu XD. The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell. 2012 Aug 10; 47(3):422-33. PMID: 22727668.
      View in: PubMed
    54. Cardamone MD, Krones A, Tanasa B, Taylor H, Ricci L, Ohgi KA, Glass CK, Rosenfeld MG, Perissi V. A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2. Mol Cell. 2012 Apr 13; 46(1):91-104. PMID: 22424771; PMCID: PMC3327812.
    55. Li H, Zhou H, Wang D, Qiu J, Zhou Y, Li X, Rosenfeld MG, Ding S, Fu XD. Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4609-14. PMID: 22396588; PMCID: PMC3311343.
    56. Sun Y, Teng I, Huo R, Rosenfeld MG, Olson LE, Li X, Li X. Asymmetric requirement of surface epithelial ß-catenin during the upper and lower jaw development. Dev Dyn. 2012 Apr; 241(4):663-74. PMID: 22354888; PMCID: PMC3308359.
    57. Lin C, Yang L, Rosenfeld MG. Molecular logic underlying chromosomal translocations, random or non-random? Adv Cancer Res. 2012; 113:241-79. PMID: 22429857.
      View in: PubMed
    58. Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 2011 Dec; 7(12):e1002401. PMID: 22174696; PMCID: PMC3234212.
    59. Yang L, Lin C, Liu W, Zhang J, Ohgi KA, Grinstein JD, Dorrestein PC, Rosenfeld MG. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell. 2011 Nov 11; 147(4):773-88. PMID: 22078878; PMCID: PMC3297197.
    60. Grossman TR, Gamliel A, Wessells RJ, Taghli-Lamallem O, Jepsen K, Ocorr K, Korenberg JR, Peterson KL, Rosenfeld MG, Bodmer R, Bier E. Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS Genet. 2011 Nov; 7(11):e1002344. PMID: 22072978; PMCID: PMC3207880.
    61. Yang L, Lin C, Rosenfeld MG. A lincRNA switch for embryonic stem cell fate. Cell Res. 2011 Dec; 21(12):1646-8. PMID: 22025254; PMCID: PMC3357988.
    62. Wang J, Geesman GJ, Hostikka SL, Atallah M, Blackwell B, Lee E, Cook PJ, Pasaniuc B, Shariat G, Halperin E, Dobke M, Rosenfeld MG, Jordan IK, Lunyak VV. Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle. 2011 Sep 01; 10(17):3016-30. PMID: 21862875; PMCID: PMC3218602.
    63. Puc J, Rosenfeld MG. SOX2 and CHD7 cooperatively regulate human disease genes. Nat Genet. 2011 Jun; 43(6):505-6. PMID: 21614087.
      View in: PubMed
    64. Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011 May 15; 474(7351):390-4. PMID: 21572438; PMCID: PMC3117022.
    65. Macfarlan TS, Gifford WD, Agarwal S, Driscoll S, Lettieri K, Wang J, Andrews SE, Franco L, Rosenfeld MG, Ren B, Pfaff SL. Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes Dev. 2011 Mar 15; 25(6):594-607. PMID: 21357675; PMCID: PMC3059833.
    66. Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8. PMID: 21331046; PMCID: PMC3464905.
    67. Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. 9p21 DNA variants associated with coronary artery disease impair interferon-? signalling response. Nature. 2011 Feb 10; 470(7333):264-8. PMID: 21307941; PMCID: PMC3079517.
    68. Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. KSRP Promotes the Maturation of a Group of miRNA Precuresors. Adv Exp Med Biol. 2011; 700:36-42. PMID: 21755471.
      View in: PubMed
    69. Wang X, Song X, Glass CK, Rosenfeld MG. The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a003756. PMID: 20573714; PMCID: PMC3003465.
    70. Kim HJ, Rosenfeld MG. Epigenetic control of stem cell fate to neurons and glia. Arch Pharm Res. 2010 Oct; 33(10):1467-73. PMID: 21052927.
      View in: PubMed
    71. Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12. PMID: 20622854; PMCID: PMC3059551.
    72. Perissi V, Jepsen K, Glass CK, Rosenfeld MG. Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet. 2010 Feb; 11(2):109-23. PMID: 20084085.
      View in: PubMed
    73. Lee JM, Kim IS, Kim H, Lee JS, Kim K, Yim HY, Jeong J, Kim JH, Kim JY, Lee H, Seo SB, Kim H, Rosenfeld MG, Kim KI, Baek SH. RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer. Mol Cell. 2010 Jan 29; 37(2):183-95. PMID: 20122401.
      View in: PubMed
    74. Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. KSRP promotes the maturation of a group of miRNA precursors. Adv Exp Med Biol. 2010; 700:36-42. PMID: 21627028.
      View in: PubMed
    75. Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P. Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation. Cell Death Differ. 2010 Jun; 17(6):975-83. PMID: 20019746.
      View in: PubMed
    76. Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 2009 Dec 11; 139(6):1069-83. PMID: 19962179; PMCID: PMC2812435.
    77. Mohla S, Stearns V, Sathyamoorthy N, Rosenfeld MG, Nelson P. The biology of hormone refractory breast and prostate cancer: An NCI workshop report. Cancer Biol Ther. 2009 Nov; 8(21):1975-85. PMID: 19783900.
      View in: PubMed
    78. Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R. How to control miRNA maturation? RNA Biol. 2009 Nov-Dec; 6(5):536-40. PMID: 19875945.
      View in: PubMed
    79. Nunez E, Fu XD, Rosenfeld MG. Nuclear organization in the 3D space of the nucleus - cause or consequence? Curr Opin Genet Dev. 2009 Oct; 19(5):424-36. PMID: 19846290; PMCID: PMC2796509.
    80. Zhong XY, Wang P, Han J, Rosenfeld MG, Fu XD. SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Mol Cell. 2009 Jul 10; 35(1):1-10. PMID: 19595711; PMCID: PMC2744344.
    81. Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell. 2009 Jul 10; 35(1):48-57. PMID: 19595715; PMCID: PMC2759189.
    82. Kurokawa R, Rosenfeld MG, Glass CK. Transcriptional regulation through noncoding RNAs and epigenetic modifications. RNA Biol. 2009 Jul-Aug; 6(3):233-6. PMID: 19411842.
      View in: PubMed
    83. Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature. 2009 Jun 18; 459(7249):1010-4. PMID: 19458619.
      View in: PubMed
    84. Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, Rosenfeld MG, Briata P, Gherzi R. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J. 2009 Sep; 23(9):2898-908. PMID: 19423639.
      View in: PubMed
    85. Cardamone MD, Bardella C, Gutierrez A, Di Croce L, Rosenfeld MG, Di Renzo MF, De Bortoli M. ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7420-5. PMID: 19383788; PMCID: PMC2671327.
    86. Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 2009 Apr 03; 137(1):47-59. PMID: 19345186; PMCID: PMC2754279.
    87. Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93. PMID: 19299558; PMCID: PMC2661610.
    88. Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6. PMID: 19234442; PMCID: PMC2692521.
    89. Li H, Lovci MT, Kwon YS, Rosenfeld MG, Fu XD, Yeo GW. Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20179-84. PMID: 19088194.
      View in: PubMed
    90. Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A. 2008 12 09; 105(49):19199-204. PMID: 19052240.
      View in: PubMed
    91. Zhou W, Wang X, Rosenfeld MG. Histone H2A ubiquitination in transcriptional regulation and DNA damage repair. Int J Biochem Cell Biol. 2009 Jan; 41(1):12-5. PMID: 18929679.
      View in: PubMed
    92. Jeong J, Li X, McEvilly RJ, Rosenfeld MG, Lufkin T, Rubenstein JL. Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development. 2008 Sep; 135(17):2905-16. PMID: 18697905; PMCID: PMC4913551.
    93. Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Jul 11; 134(1):189. PMID: 18630350.
      View in: PubMed
    94. Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG, Glass CK, Kurokawa R. Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature. 2008 Jul 03; 454(7200):126-30. PMID: 18509338; PMCID: PMC2823488.
    95. Gleiberman AS, Michurina T, Encinas JM, Roig JL, Krasnov P, Balordi F, Fishell G, Rosenfeld MG, Enikolopov G. Genetic approaches identify adult pituitary stem cells. Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17):6332-7. PMID: 18436641; PMCID: PMC2359820.
    96. Lunyak VV, Rosenfeld MG. Epigenetic regulation of stem cell fate. Hum Mol Genet. 2008 Apr 15; 17(R1):R28-36. PMID: 18632693.
      View in: PubMed
    97. Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66. PMID: 18374649; PMCID: PMC2364611.
    98. Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Mar 21; 132(6):996-1010. PMID: 18358812.
      View in: PubMed
    99. Jepsen K, Gleiberman AS, Shi C, Simon DI, Rosenfeld MG. Cooperative regulation in development by SMRT and FOXP1. Genes Dev. 2008 Mar 15; 22(6):740-5. PMID: 18347093; PMCID: PMC2275427.
    100. Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carrière C. Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2481-6. PMID: 18272476; PMCID: PMC2268162.
    101. Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG. Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell. 2008 Jan 18; 29(1):69-80. PMID: 18206970; PMCID: PMC2327256.
    102. Zhu X, Wang J, Ju BG, Rosenfeld MG. Signaling and epigenetic regulation of pituitary development. Curr Opin Cell Biol. 2007 Dec; 19(6):605-11. PMID: 17988851; PMCID: PMC2796608.
    103. Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG. SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15; 450(7168):415-9. PMID: 17928865.
      View in: PubMed
    104. Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet. 2007 Oct; 39(10):1225-34. PMID: 17767158.
      View in: PubMed
    105. Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, Erdjument-Bromage H, Tempst P, Glass CK, Rosenfeld MG. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell. 2007 Aug 17; 27(4):609-21. PMID: 17707232; PMCID: PMC2709280.
    106. Lunyak VV, Prefontaine GG, Núñez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, García-Díaz A, Zhu X, Yung Y, Montoliu L, Glass CK, Rosenfeld MG. Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science. 2007 Jul 13; 317(5835):248-51. PMID: 17626886.
      View in: PubMed
    107. Zhu X, Gleiberman AS, Rosenfeld MG. Molecular physiology of pituitary development: signaling and transcriptional networks. Physiol Rev. 2007 Jul; 87(3):933-63. PMID: 17615393.
      View in: PubMed
    108. Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816. PMID: 17571346.
      View in: PubMed
    109. Xiao R, Sun Y, Ding JH, Lin S, Rose DW, Rosenfeld MG, Fu XD, Li X. Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007 Aug; 27(15):5393-402. PMID: 17526736; PMCID: PMC1952092.
    110. Lin L, Cui L, Zhou W, Dufort D, Zhang X, Cai CL, Bu L, Yang L, Martin J, Kemler R, Rosenfeld MG, Chen J, Evans SM. Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A. 2007 May 29; 104(22):9313-8. PMID: 17519333; PMCID: PMC1890491.
    111. Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG. Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19; 446(7138):882-7. PMID: 17392792.
      View in: PubMed
    112. Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):4852-7. PMID: 17360330; PMCID: PMC1821125.
    113. Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518. PMID: 17289570; PMCID: PMC1994663.
    114. Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK. Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007 Jan 12; 25(1):57-70. PMID: 17218271; PMCID: PMC1850387.
    115. Pascual G, Sullivan AL, Ogawa S, Gamliel A, Perissi V, Rosenfeld MG, Glass CK. Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Found Symp. 2007; 286:183-96; discussion 196-203. PMID: 18269183.
      View in: PubMed
    116. Ju BG, Rosenfeld MG. A breaking strategy for topoisomerase IIbeta/PARP-1-dependent regulated transcription. Cell Cycle. 2006 Nov; 5(22):2557-60. PMID: 17106262.
      View in: PubMed
    117. Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG. Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 01; 20(19):2739-53. PMID: 17015435; PMCID: PMC1578699.
    118. Bush KT, Vaughn DA, Li X, Rosenfeld MG, Rose DW, Mendoza SA, Nigam SK. Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system. Dev Biol. 2006 Oct 15; 298(2):571-84. PMID: 16934795.
      View in: PubMed
    119. Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG. A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science. 2006 Jun 23; 312(5781):1798-802. PMID: 16794079.
      View in: PubMed
    120. Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A. Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res. 2006 Jun 01; 66(11):5565-73. PMID: 16740691.
      View in: PubMed
    121. Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 2006 Jun 01; 20(11):1405-28. PMID: 16751179.
      View in: PubMed
    122. Rosenfeld MG. An interview with Michael G. Rosenfeld, M.D. Assay Drug Dev Technol. 2006 Jun; 4(3):235-8. PMID: 16834529.
      View in: PubMed
    123. Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG. Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 05; 125(3):593-605. PMID: 16678101.
      View in: PubMed
    124. Baek SH, Ohgi KA, Nelson CA, Welsbie D, Chen C, Sawyers CL, Rose DW, Rosenfeld MG. Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3100-5. PMID: 16492776; PMCID: PMC1413901.
    125. Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H, Akira S, Kotol PF, Glass CK, Rosenfeld MG, Rose DW. Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell. 2006 Feb 10; 124(3):615-29. PMID: 16469706.
      View in: PubMed
    126. Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T. Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metab. 2006 Feb; 3(2):111-22. PMID: 16459312.
      View in: PubMed
    127. Gleiberman AS, Encinas JM, Mignone JL, Michurina T, Rosenfeld MG, Enikolopov G. Expression of nestin-green fluorescent protein transgene marks oval cells in the adult liver. Dev Dyn. 2005 Oct; 234(2):413-21. PMID: 16127706; PMCID: PMC2751636.
    128. Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21. PMID: 16143103; PMCID: PMC1430687.
    129. Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature. 2005 Sep 29; 437(7059):759-63. PMID: 16127449; PMCID: PMC1464798.
    130. Perissi V, Rosenfeld MG. Controlling nuclear receptors: the circular logic of cofactor cycles. Nat Rev Mol Cell Biol. 2005 Jul; 6(7):542-54. PMID: 15957004.
      View in: PubMed
    131. Zhu X, Lin CR, Prefontaine GG, Tollkuhn J, Rosenfeld MG. Genetic control of pituitary development and hypopituitarism. Curr Opin Genet Dev. 2005 Jun; 15(3):332-40. PMID: 15917210.
      View in: PubMed
    132. Lunyak VV, Rosenfeld MG. No rest for REST: REST/NRSF regulation of neurogenesis. Cell. 2005 May 20; 121(4):499-501. PMID: 15907461.
      View in: PubMed
    133. Kim TH, Barrera LO, Qu C, Van Calcar S, Trinklein ND, Cooper SJ, Luna RM, Glass CK, Rosenfeld MG, Myers RM, Ren B. Direct isolation and identification of promoters in the human genome. Genome Res. 2005 Jun; 15(6):830-9. PMID: 15899964; PMCID: PMC1142473.
    134. Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S. T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May; 132(10):2475-87. PMID: 15843407.
      View in: PubMed
    135. Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature. 2005 Apr 14; 434(7035):921-6. PMID: 15829968.
      View in: PubMed
    136. Olson LE, Zhang J, Taylor H, Rose DW, Rosenfeld MG. Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling. Proc Natl Acad Sci U S A. 2005 Mar 08; 102(10):3708-13. PMID: 15728386; PMCID: PMC553323.
    137. Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J, Chen J, Xiao RP, Cheng H, Fu XD. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005 Jan 14; 120(1):59-72. PMID: 15652482.
      View in: PubMed
    138. Telese F, Bruni P, Donizetti A, Gianni D, D'Ambrosio C, Scaloni A, Zambrano N, Rosenfeld MG, Russo T. Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep. 2005 Jan; 6(1):77-82. PMID: 15592452; PMCID: PMC1299219.
    139. Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, Rosenfeld MG. Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell. 2004 Dec 17; 119(6):815-29. PMID: 15607978.
      View in: PubMed
    140. Beischlag TV, Taylor RT, Rose DW, Yoon D, Chen Y, Lee WH, Rosenfeld MG, Hankinson O. Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia. J Biol Chem. 2004 Dec 24; 279(52):54620-8. PMID: 15485806.
      View in: PubMed
    141. Zhu X, Rosenfeld MG. Transcriptional control of precursor proliferation in the early phases of pituitary development. Curr Opin Genet Dev. 2004 Oct; 14(5):567-74. PMID: 15380249.
      View in: PubMed
    142. Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, Rose DW, Johnson RS, Rosenfeld MG, Glass CK. A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14461-6. PMID: 15452344; PMCID: PMC521940.
    143. Baek SH, Rosenfeld MG. Nuclear receptor coregulators: their modification codes and regulatory mechanism by translocation. Biochem Biophys Res Commun. 2004 Jul 02; 319(3):707-14. PMID: 15184040.
      View in: PubMed
    144. Korzus E, Rosenfeld MG, Mayford M. CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron. 2004 Jun 24; 42(6):961-72. PMID: 15207240.
      View in: PubMed
    145. Lunyak VV, Prefontaine GG, Rosenfeld MG. REST and peace for the neuronal-specific transcriptional program. Ann N Y Acad Sci. 2004 Apr; 1014:110-20. PMID: 15153425.
      View in: PubMed
    146. Toyo-oka K, Hirotsune S, Gambello MJ, Zhou ZQ, Olson L, Rosenfeld MG, Eisenman R, Hurlin P, Wynshaw-Boris A. Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Hum Mol Genet. 2004 May 15; 13(10):1057-67. PMID: 15028671.
      View in: PubMed
    147. Carrière C, Gleiberman A, Lin CR, Rosenfeld MG. From panhypopituitarism to combined pituitary deficiencies: do we need the anterior pituitary? Rev Endocr Metab Disord. 2004 Mar; 5(1):5-13. PMID: 14966385.
      View in: PubMed
    148. Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell. 2004 Feb 20; 116(4):511-26. PMID: 14980219.
      View in: PubMed
    149. Li X, Rosenfeld MG. Transcription: origins of licensing control. Nature. 2004 Feb 19; 427(6976):687-8. PMID: 14973463.
      View in: PubMed
    150. Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. Molecular determinants of resistance to antiandrogen therapy. Nat Med. 2004 Jan; 10(1):33-9. PMID: 14702632.
      View in: PubMed
    151. Gold DA, Baek SH, Schork NJ, Rose DW, Larsen DD, Sachs BD, Rosenfeld MG, Hamilton BA. RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron. 2003 Dec 18; 40(6):1119-31. PMID: 14687547; PMCID: PMC2717708.
    152. Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20; 426(6964):247-54. PMID: 14628042.
      View in: PubMed
    153. Briata P, Ilengo C, Corte G, Moroni C, Rosenfeld MG, Chen CY, Gherzi R. The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs. Mol Cell. 2003 Nov; 12(5):1201-11. PMID: 14636578.
      View in: PubMed
    154. Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK. Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol. 2003 Aug; 23(16):5780-9. PMID: 12897148; PMCID: PMC166346.
    155. Stiedl O, Meyer M, Kishimoto T, Rosenfeld MG, Spiess J. Stress-mediated heart rate dynamics after deletion of the gene encoding corticotropin-releasing factor receptor 2. Eur J Neurosci. 2003 May; 17(10):2231-5. PMID: 12786991.
      View in: PubMed
    156. Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG. Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3245-50. PMID: 12629224; PMCID: PMC152277.
    157. Olson LE, Dasen JS, Ju BG, Tollkuhn J, Rosenfeld MG. Paired-like repression/activation in pituitary development. Recent Prog Horm Res. 2003; 58:249-61. PMID: 12795422.
      View in: PubMed
    158. Murakami DM, Erkman L, Hermanson O, Rosenfeld MG, Fuller CA. Evidence for vestibular regulation of autonomic functions in a mouse genetic model. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):17078-82. PMID: 12466504; PMCID: PMC139272.
    159. Bermingham JR, Shumas S, Whisenhunt T, Sirkowski EE, O'Connell S, Scherer SS, Rosenfeld MG. Identification of genes that are downregulated in the absence of the POU domain transcription factor pou3f1 (Oct-6, Tst-1, SCIP) in sciatic nerve. J Neurosci. 2002 Dec 01; 22(23):10217-31. PMID: 12451123.
      View in: PubMed
    160. Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG. Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell. 2002 Nov 27; 111(5):673-85. PMID: 12464179.
      View in: PubMed
    161. Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG. Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science. 2002 Nov 29; 298(5599):1747-52. PMID: 12399542.
      View in: PubMed
    162. Hermanson O, Jepsen K, Rosenfeld MG. N-CoR controls differentiation of neural stem cells into astrocytes. Nature. 2002 Oct 31; 419(6910):934-9. PMID: 12410313.
      View in: PubMed
    163. Kumar V, Carlson JE, Ohgi KA, Edwards TA, Rose DW, Escalante CR, Rosenfeld MG, Aggarwal AK. Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell. 2002 Oct; 10(4):857-69. PMID: 12419229.
      View in: PubMed
    164. Burgess R, Lunyak V, Rosenfeld M. Signaling and transcriptional control of pituitary development. Curr Opin Genet Dev. 2002 Oct; 12(5):534-39. PMID: 12200158.
      View in: PubMed
    165. Battaglioli E, Andrés ME, Rose DW, Chenoweth JG, Rosenfeld MG, Anderson ME, Mandel G. REST repression of neuronal genes requires components of the hSWI.SNF complex. J Biol Chem. 2002 Oct 25; 277(43):41038-45. PMID: 12192000.
      View in: PubMed
    166. Li X, Perissi V, Liu F, Rose DW, Rosenfeld MG. Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 2002 Aug 16; 297(5584):1180-3. PMID: 12130660.
      View in: PubMed
    167. Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell. 2002 Jul 12; 110(1):55-67. PMID: 12150997.
      View in: PubMed
    168. Olson LE, Rosenfeld MG. Perspective: genetic and genomic approaches in elucidating mechanisms of pituitary development. Endocrinology. 2002 Jun; 143(6):2007-11. PMID: 12021162.
      View in: PubMed
    169. Beischlag TV, Wang S, Rose DW, Torchia J, Reisz-Porszasz S, Muhammad K, Nelson WE, Probst MR, Rosenfeld MG, Hankinson O. Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol Cell Biol. 2002 Jun; 22(12):4319-33. PMID: 12024042; PMCID: PMC133867.
    170. Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 2002 Apr 19; 109(2):169-80. PMID: 12007404.
      View in: PubMed
    171. Scully KM, Rosenfeld MG. Pituitary development: regulatory codes in mammalian organogenesis. Science. 2002 Mar 22; 295(5563):2231-5. PMID: 11910101.
      View in: PubMed
    172. Hermanson O, Glass CK, Rosenfeld MG. Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol Metab. 2002 Mar; 13(2):55-60. PMID: 11854019.
      View in: PubMed
    173. McEvilly RJ, de Diaz MO, Schonemann MD, Hooshmand F, Rosenfeld MG. Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22; 295(5559):1528-32. PMID: 11859196.
      View in: PubMed
    174. Jepsen K, Rosenfeld MG. Biological roles and mechanistic actions of co-repressor complexes. J Cell Sci. 2002 Feb 15; 115(Pt 4):689-98. PMID: 11865025.
      View in: PubMed
    175. Kioussi C, Briata P, Baek SH, Wynshaw-Boris A, Rose DW, Rosenfeld MG. Pitx genes during cardiovascular development. Cold Spring Harb Symp Quant Biol. 2002; 67:81-7. PMID: 12858527.
      View in: PubMed
    176. Dasen JS, Martinez Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG. Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 01; 15(23):3193-207. PMID: 11731482.
      View in: PubMed
    177. Rosenfeld MG, Glass CK. Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem. 2001 Oct 05; 276(40):36865-8. PMID: 11459854.
      View in: PubMed
    178. Liu J, Lin C, Gleiberman A, Ohgi KA, Herman T, Huang HP, Tsai MJ, Rosenfeld MG. Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8674-9. PMID: 11447259.
      View in: PubMed
    179. Andersen B, Rosenfeld MG. POU domain factors in the neuroendocrine system: lessons from developmental biology provide insights into human disease. Endocr Rev. 2001 Feb; 22(1):2-35. PMID: 11159814.
      View in: PubMed
    180. Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb; 128(3):377-86. PMID: 11152636.
      View in: PubMed
    181. Dasen JS, Rosenfeld MG. Signaling and transcriptional mechanisms in pituitary development. Annu Rev Neurosci. 2001; 24:327-55. PMID: 11283314.
      View in: PubMed
    182. Wang Z, Rose DW, Hermanson O, Liu F, Herman T, Wu W, Szeto D, Gleiberman A, Krones A, Pratt K, Rosenfeld R, Glass CK, Rosenfeld MG. Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13549-54. PMID: 11087842.
      View in: PubMed
    183. Erkman L, Yates PA, McLaughlin T, McEvilly RJ, Whisenhunt T, O'Connell SM, Krones AI, Kirby MA, Rapaport DH, Bermingham JR, O'Leary DD, Rosenfeld MG. A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system. Neuron. 2000 Dec; 28(3):779-92. PMID: 11163266.
      View in: PubMed
    184. Scully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carrière C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG. Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science. 2000 Nov 10; 290(5494):1127-31. PMID: 11073444.
      View in: PubMed
    185. Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E, Hedrick SM, Mandel G, Glass CK, Rose DW, Rosenfeld MG. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell. 2000 Sep 15; 102(6):753-63. PMID: 11030619.
      View in: PubMed
    186. Llopis J, Westin S, Ricote M, Wang Z, Cho CY, Kurokawa R, Mullen TM, Rose DW, Rosenfeld MG, Tsien RY, Glass CK, Wang J. Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4363-8. PMID: 10760302.
      View in: PubMed
    187. Kishimoto T, Radulovic J, Radulovic M, Lin CR, Schrick C, Hooshmand F, Hermanson O, Rosenfeld MG, Spiess J. Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. Nat Genet. 2000 Apr; 24(4):415-9. PMID: 10742109.
      View in: PubMed
    188. Glass CK, Rosenfeld MG. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 2000 Jan 15; 14(2):121-41. PMID: 10652267.
      View in: PubMed
    189. Westin S, Rosenfeld MG, Glass CK. Nuclear receptor coactivators. Adv Pharmacol. 2000; 47:89-112. PMID: 10582085.
      View in: PubMed
    190. Rosenfeld MG, Briata P, Dasen J, Gleiberman AS, Kioussi C, Lin C, O'Connell SM, Ryan A, Szeto DP, Treier M. Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo. Recent Prog Horm Res. 2000; 55:1-13; discussion 13-4. PMID: 11036930.
      View in: PubMed
    191. Perissi V, Staszewski LM, McInerney EM, Kurokawa R, Krones A, Rose DW, Lambert MH, Milburn MV, Glass CK, Rosenfeld MG. Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev. 1999 Dec 15; 13(24):3198-208. PMID: 10617569.
      View in: PubMed
    192. Kioussi C, O'Connell S, St-Onge L, Treier M, Gleiberman AS, Gruss P, Rosenfeld MG. Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14378-82. PMID: 10588713.
      View in: PubMed
    193. Dasen JS, Rosenfeld MG. Signaling mechanisms in pituitary morphogenesis and cell fate determination. Curr Opin Cell Biol. 1999 Dec; 11(6):669-77. PMID: 10600709.
      View in: PubMed
    194. Dasen JS, Rosenfeld MG. Combinatorial codes in signaling and synergy: lessons from pituitary development. Curr Opin Genet Dev. 1999 Oct; 9(5):566-74. PMID: 10508698.
      View in: PubMed
    195. Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisúa-Belmonte JC, Rosenfeld MG. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999 Sep 16; 401(6750):279-82. PMID: 10499586.
      View in: PubMed
    196. Bach I, Rodriguez-Esteban C, Carrière C, Bhushan A, Krones A, Rose DW, Glass CK, Andersen B, Izpisúa Belmonte JC, Rosenfeld MG. RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. Nat Genet. 1999 Aug; 22(4):394-9. PMID: 10431247.
      View in: PubMed
    197. Kioussi C, Rosenfeld MG. Body's left side. Cell Mol Biol (Noisy-le-grand). 1999 Jul; 45(5):517-22. PMID: 10512184.
      View in: PubMed
    198. Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG. Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28; 97(5):587-98. PMID: 10367888.
      View in: PubMed
    199. Xu L, Glass CK, Rosenfeld MG. Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev. 1999 Apr; 9(2):140-7. PMID: 10322133.
      View in: PubMed
    200. Perissi V, Dasen JS, Kurokawa R, Wang Z, Korzus E, Rose DW, Glass CK, Rosenfeld MG. Factor-specific modulation of CREB-binding protein acetyltransferase activity. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3652-7. PMID: 10097092.
      View in: PubMed
    201. Kioussi C, Carrière C, Rosenfeld MG. A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis. Mech Dev. 1999 Mar; 81(1-2):23-35. PMID: 10330482.
      View in: PubMed
    202. Szeto DP, Rodriguez-Esteban C, Ryan AK, O'Connell SM, Liu F, Kioussi C, Gleiberman AS, Izpisúa-Belmonte JC, Rosenfeld MG. Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 Feb 15; 13(4):484-94. PMID: 10049363.
      View in: PubMed
    203. Sornson MW, Rosenfeld MG. Genetically directed representational difference analysis-based positional cloning and snorthern analysis of candidate genes. Methods Enzymol. 1999; 306:67-89. PMID: 10432448.
      View in: PubMed
    204. McEvilly RJ, Rosenfeld MG. The role of POU domain proteins in the regulation of mammalian pituitary and nervous system development. Prog Nucleic Acid Res Mol Biol. 1999; 63:223-55. PMID: 10506833.
      View in: PubMed
    205. Sugihara TM, Bach I, Kioussi C, Rosenfeld MG, Andersen B. Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15418-23. PMID: 9860983.
      View in: PubMed
    206. McInerney EM, Rose DW, Flynn SE, Westin S, Mullen TM, Krones A, Inostroza J, Torchia J, Nolte RT, Assa-Munt N, Milburn MV, Glass CK, Rosenfeld MG. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 1998 Nov 01; 12(21):3357-68. PMID: 9808623.
      View in: PubMed
    207. Xu L, Lavinsky RM, Dasen JS, Flynn SE, McInerney EM, Mullen TM, Heinzel T, Szeto D, Korzus E, Kurokawa R, Aggarwal AK, Rose DW, Glass CK, Rosenfeld MG. Signal-specific co-activator domain requirements for Pit-1 activation. Nature. 1998 Sep 17; 395(6699):301-6. PMID: 9751061.
      View in: PubMed
    208. Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, Milburn MV, Rosenfeld MG, Glass CK. Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature. 1998 Sep 10; 395(6698):199-202. PMID: 9744281.
      View in: PubMed
    209. Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC. Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature. 1998 Aug 06; 394(6693):545-51. PMID: 9707115.
      View in: PubMed
    210. Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG. Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 1998 Jun 01; 12(11):1691-704. PMID: 9620855.
      View in: PubMed
    211. Torchia J, Glass C, Rosenfeld MG. Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol. 1998 Jun; 10(3):373-83. PMID: 9640539.
      View in: PubMed
    212. Lavinsky RM, Jepsen K, Heinzel T, Torchia J, Mullen TM, Schiff R, Del-Rio AL, Ricote M, Ngo S, Gemsch J, Hilsenbeck SG, Osborne CK, Glass CK, Rosenfeld MG, Rose DW. Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2920-5. PMID: 9501191.
      View in: PubMed
    213. Wu W, Cogan JD, Pfäffle RW, Dasen JS, Frisch H, O'Connell SM, Flynn SE, Brown MR, Mullis PE, Parks JS, Phillips JA, Rosenfeld MG. Mutations in PROP1 cause familial combined pituitary hormone deficiency. Nat Genet. 1998 Feb; 18(2):147-9. PMID: 9462743.
      View in: PubMed
    214. Kurokawa R, Kalafus D, Ogliastro MH, Kioussi C, Xu L, Torchia J, Rosenfeld MG, Glass CK. Differential use of CREB binding protein-coactivator complexes. Science. 1998 Jan 30; 279(5351):700-3. PMID: 9445474.
      View in: PubMed
    215. Korzus E, Torchia J, Rose DW, Xu L, Kurokawa R, McInerney EM, Mullen TM, Glass CK, Rosenfeld MG. Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science. 1998 Jan 30; 279(5351):703-7. PMID: 9445475.
      View in: PubMed
    216. Schonemann MD, Ryan AK, Erkman L, McEvilly RJ, Bermingham J, Rosenfeld MG. POU domain factors in neural development. Adv Exp Med Biol. 1998; 449:39-53. PMID: 10026784.
      View in: PubMed
    217. Hedjran F, Yeakley JM, Huh GS, Hynes RO, Rosenfeld MG. Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12343-7. PMID: 9356451.
      View in: PubMed
    218. Andersen B, Weinberg WC, Rennekampff O, McEvilly RJ, Bermingham JR, Hooshmand F, Vasilyev V, Hansbrough JF, Pittelkow MR, Yuspa SH, Rosenfeld MG. Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev. 1997 Jul 15; 11(14):1873-84. PMID: 9242494.
      View in: PubMed
    219. Pearse RV, Drolet DW, Kalla KA, Hooshmand F, Bermingham JR, Rosenfeld MG. Reduced fertility in mice deficient for the POU protein sperm-1. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7555-60. PMID: 9207130.
      View in: PubMed
    220. Andersen B, Hariri A, Pittelkow MR, Rosenfeld MG. Characterization of Skn-1a/i POU domain factors and linkage to papillomavirus gene expression. J Biol Chem. 1997 Jun 20; 272(25):15905-13. PMID: 9188490.
      View in: PubMed
    221. Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK, Rosenfeld MG. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature. 1997 Jun 12; 387(6634):677-84. PMID: 9192892.
      View in: PubMed
    222. Söderström M, Vo A, Heinzel T, Lavinsky RM, Yang WM, Seto E, Peterson DA, Rosenfeld MG, Glass CK. Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Mol Endocrinol. 1997 Jun; 11(6):682-92. PMID: 9171232.
      View in: PubMed
    223. Scully KM, Gleiberman AS, Lindzey J, Lubahn DB, Korach KS, Rosenfeld MG. Role of estrogen receptor-alpha in the anterior pituitary gland. Mol Endocrinol. 1997 Jun; 11(6):674-81. PMID: 9171231.
      View in: PubMed
    224. Bach I, Carrière C, Ostendorff HP, Andersen B, Rosenfeld MG. A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev. 1997 Jun 01; 11(11):1370-80. PMID: 9192866.
      View in: PubMed
    225. Ryan AK, Rosenfeld MG. POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev. 1997 May 15; 11(10):1207-25. PMID: 9171367.
      View in: PubMed
    226. Glass CK, Rosenfeld MG, Rose DW, Kurokawa R, Kamei Y, Xu L, Torchia J, Ogliastro MH, Westin S. Mechanisms of transcriptional activation by retinoic acid receptors. Biochem Soc Trans. 1997 May; 25(2):602-5. PMID: 9191164.
      View in: PubMed
    227. Heinzel T, Lavinsky RM, Mullen TM, Söderstrom M, Laherty CD, Torchia J, Yang WM, Brard G, Ngo SD, Davie JR, Seto E, Eisenman RN, Rose DW, Glass CK, Rosenfeld MG. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature. 1997 May 01; 387(6628):43-8. PMID: 9139820.
      View in: PubMed
    228. DiRenzo J, Söderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Hörlein A, Rosenfeld MG, Glass CK. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol Cell Biol. 1997 Apr; 17(4):2166-76. PMID: 9121466.
      View in: PubMed
    229. Glass CK, Rose DW, Rosenfeld MG. Nuclear receptor coactivators. Curr Opin Cell Biol. 1997 Apr; 9(2):222-32. PMID: 9069256.
      View in: PubMed
    230. Horvai AE, Xu L, Korzus E, Brard G, Kalafus D, Mullen TM, Rose DW, Rosenfeld MG, Glass CK. Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1074-9. PMID: 9037008; PMCID: PMC19746.
    231. DiMattia GE, Rhodes SJ, Krones A, Carrière C, O'Connell S, Kalla K, Arias C, Sawchenko P, Rosenfeld MG. The Pit-1 gene is regulated by distinct early and late pituitary-specific enhancers. Dev Biol. 1997 Feb 01; 182(1):180-90. PMID: 9073460.
      View in: PubMed
    232. McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG. Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12; 384(6609):574-7. PMID: 8955272.
      View in: PubMed
    233. Treier M, Rosenfeld MG. The hypothalamic-pituitary axis: co-development of two organs. Curr Opin Cell Biol. 1996 Dec; 8(6):833-43. PMID: 8939677.
      View in: PubMed
    234. Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O'Connell SM, Gukovsky I, Carrière C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG. Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 1996 Nov 28; 384(6607):327-33. PMID: 8934515.
      View in: PubMed
    235. Yeakley JM, Morfin JP, Rosenfeld MG, Fu XD. A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7582-7. PMID: 8755518.
      View in: PubMed
    236. Szeto DP, Ryan AK, O'Connell SM, Rosenfeld MG. P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7706-10. PMID: 8755540.
      View in: PubMed
    237. Bermingham JR, Scherer SS, O'Connell S, Arroyo E, Kalla KA, Powell FL, Rosenfeld MG. Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev. 1996 Jul 15; 10(14):1751-62. PMID: 8698235.
      View in: PubMed
    238. Erkman L, McEvilly RJ, Luo L, Ryan AK, Hooshmand F, O'Connell SM, Keithley EM, Rapaport DH, Ryan AF, Rosenfeld MG. Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature. 1996 Jun 13; 381(6583):603-6. PMID: 8637595.
      View in: PubMed
    239. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell. 1996 May 03; 85(3):403-14. PMID: 8616895.
      View in: PubMed
    240. Rosenfeld MG, Bach I, Erkman L, Li P, Lin C, Lin S, McEvilly R, Ryan A, Rhodes S, Schonnemann M, Scully K. Transcriptional control of cell phenotypes in the neuroendocrine system. Recent Prog Horm Res. 1996; 51:217-38; discussion 238-9. PMID: 8701080.
      View in: PubMed
    241. Schonemann MD, Ryan AK, McEvilly RJ, O'Connell SM, Arias CA, Kalla KA, Li P, Sawchenko PE, Rosenfeld MG. Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev. 1995 Dec 15; 9(24):3122-35. PMID: 8543156.
      View in: PubMed
    242. Andersen B, Pearse RV, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG. The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec; 172(2):495-503. PMID: 8612966.
      View in: PubMed
    243. Kurokawa R, Söderström M, Hörlein A, Halachmi S, Brown M, Rosenfeld MG, Glass CK. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature. 1995 Oct 05; 377(6548):451-4. PMID: 7566126.
      View in: PubMed
    244. Bermingham JR, Arden KC, Naumova AK, Sapienza C, Viars CS, Fu XD, Khotz J, Manley JL, Rosenfeld MG. Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2). Genomics. 1995 Sep 01; 29(1):70-9. PMID: 8530103.
      View in: PubMed
    245. Holloway JM, Szeto DP, Scully KM, Glass CK, Rosenfeld MG. Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev. 1995 Aug 15; 9(16):1992-2006. PMID: 7649480.
      View in: PubMed
    246. Bach I, Rhodes SJ, Pearse RV, Heinzel T, Gloss B, Scully KM, Sawchenko PE, Rosenfeld MG. P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2720-4. PMID: 7708713; PMCID: PMC42290.
    247. Kishimoto T, Pearse RV, Lin CR, Rosenfeld MG. A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle. Proc Natl Acad Sci U S A. 1995 Feb 14; 92(4):1108-12. PMID: 7755719.
      View in: PubMed
    248. Andersen B, Rosenfeld MG. Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis. J Biol Chem. 1994 Nov 25; 269(47):29335-8. PMID: 7961905.
      View in: PubMed
    249. Kurokawa R, DiRenzo J, Boehm M, Sugarman J, Gloss B, Rosenfeld MG, Heyman RA, Glass CK. Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature. 1994 Oct 06; 371(6497):528-31. PMID: 7935766.
      View in: PubMed
    250. Rhodes SJ, DiMattia GE, Rosenfeld MG. Transcriptional mechanisms in anterior pituitary cell differentiation. Curr Opin Genet Dev. 1994 Oct; 4(5):709-17. PMID: 7849511.
      View in: PubMed
    251. Lin SC, Li S, Drolet DW, Rosenfeld MG. Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope. Development. 1994 Mar; 120(3):515-22. PMID: 8162852.
      View in: PubMed
    252. Turner EE, Jenne KJ, Rosenfeld MG. Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron. 1994 Jan; 12(1):205-18. PMID: 7904822.
      View in: PubMed
    253. Voss JW, Wilson L, Rhodes SJ, Rosenfeld MG. An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain. Mol Endocrinol. 1993 Dec; 7(12):1551-60. PMID: 8145762.
      View in: PubMed
    254. Andersen B, Pearse RV, Schlegel PN, Cichon Z, Schonemann MD, Bardin CW, Rosenfeld MG. Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell. Proc Natl Acad Sci U S A. 1993 Dec 01; 90(23):11084-8. PMID: 7902581.
      View in: PubMed
    255. Chang CP, Pearse RV, O'Connell S, Rosenfeld MG. Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. Neuron. 1993 Dec; 11(6):1187-95. PMID: 8274282.
      View in: PubMed
    256. Li P, He X, Gerrero MR, Mok M, Aggarwal A, Rosenfeld MG. Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Genes Dev. 1993 Dec; 7(12B):2483-96. PMID: 8276233.
      View in: PubMed
    257. Gerrero MR, McEvilly RJ, Turner E, Lin CR, O'Connell S, Jenne KJ, Hobbs MV, Rosenfeld MG. Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10841-5. PMID: 8248179.
      View in: PubMed
    258. Andersen B, Schonemann MD, Pearse RV, Jenne K, Sugarman J, Rosenfeld MG. Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. J Biol Chem. 1993 Nov 05; 268(31):23390-8. PMID: 7901208.
      View in: PubMed
    259. Yeakley JM, Hedjran F, Morfin JP, Merillat N, Rosenfeld MG, Emeson RB. Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Mol Cell Biol. 1993 Oct; 13(10):5999-6011. PMID: 8413203.
      View in: PubMed
    260. Chang CP, Lazar CS, Walsh BJ, Komuro M, Collawn JF, Kuhn LA, Tainer JA, Trowbridge IS, Farquhar MG, Rosenfeld MG. Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem. 1993 Sep 15; 268(26):19312-20. PMID: 8396132.
      View in: PubMed
    261. Lipkin SM, Näär AM, Kalla KA, Sack RA, Rosenfeld MG. Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. Genes Dev. 1993 Sep; 7(9):1674-87. PMID: 8370519.
      View in: PubMed
    262. Lin SC, Lin CR, Gukovsky I, Lusis AJ, Sawchenko PE, Rosenfeld MG. Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature. 1993 Jul 15; 364(6434):208-13. PMID: 8391647.
      View in: PubMed
    263. Kurokawa R, Yu VC, Näär A, Kyakumoto S, Han Z, Silverman S, Rosenfeld MG, Glass CK. Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev. 1993 Jul; 7(7B):1423-35. PMID: 8392479.
      View in: PubMed
    264. Wegner M, Drolet DW, Rosenfeld MG. POU-domain proteins: structure and function of developmental regulators. Curr Opin Cell Biol. 1993 Jun; 5(3):488-98. PMID: 8352967.
      View in: PubMed
    265. Rhodes SJ, Chen R, DiMattia GE, Scully KM, Kalla KA, Lin SC, Yu VC, Rosenfeld MG. A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene. Genes Dev. 1993 Jun; 7(6):913-32. PMID: 8504933.
      View in: PubMed
    266. Wegner M, Drolet DW, Rosenfeld MG. Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4743-7. PMID: 8389455.
      View in: PubMed
    267. Lira SA, Kalla KA, Glass CK, Drolet DW, Rosenfeld MG. Synergistic interactions between Pit-1 and other elements are required for effective somatotroph rat growth hormone gene expression in transgenic mice. Mol Endocrinol. 1993 May; 7(5):694-701. PMID: 8316253.
      View in: PubMed
    268. Andersen B, Schonemann MD, Flynn SE, Pearse RV, Singh H, Rosenfeld MG. Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis. Science. 1993 Apr 02; 260(5104):78-82. PMID: 7682011.
      View in: PubMed
    269. Lin C, Lin SC, Chang CP, Rosenfeld MG. Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth. Nature. 1992 Dec 24-31; 360(6406):765-8. PMID: 1334535.
      View in: PubMed
    270. Yu VC, Näär AM, Rosenfeld MG. Transcriptional regulation by the nuclear receptor superfamily. Curr Opin Biotechnol. 1992 Dec; 3(6):597-602. PMID: 1369415.
      View in: PubMed
    271. Voss JW, Rosenfeld MG. Anterior pituitary development: short tales from dwarf mice. Cell. 1992 Aug 21; 70(4):527-30. PMID: 1505020.
      View in: PubMed
    272. Delsert CD, Rosenfeld MG. A tissue-specific small nuclear ribonucleoprotein and the regulated splicing of the calcitonin/calcitonin gene-related protein transcript. J Biol Chem. 1992 Jul 25; 267(21):14573-9. PMID: 1386079.
      View in: PubMed
    273. Mathis JM, Simmons DM, He X, Swanson LW, Rosenfeld MG. Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 1992 Jul; 11(7):2551-61. PMID: 1628619.
      View in: PubMed
    274. Rosenfeld MG, Emeson RB, Yeakley JM, Merillat N, Hedjran F, Lenz J, Delsert C. Calcitonin gene-related peptide: a neuropeptide generated as a consequence of tissue-specific, developmentally regulated alternative RNA processing events. Ann N Y Acad Sci. 1992 Jun 30; 657:1-17. PMID: 1637077.
      View in: PubMed
    275. Wegner M, Cao Z, Rosenfeld MG. Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta. Science. 1992 Apr 17; 256(5055):370-3. PMID: 1314426.
      View in: PubMed
    276. Lipkin SM, Nelson CA, Glass CK, Rosenfeld MG. A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1209-13. PMID: 1311087.
      View in: PubMed
    277. Treacy MN, Neilson LI, Turner EE, He X, Rosenfeld MG. Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription. Cell. 1992 Feb 07; 68(3):491-505. PMID: 1346754.
      View in: PubMed
    278. Treacy MN, Rosenfeld MG. Expression of a family of POU-domain protein regulatory genes during development of the central nervous system. Annu Rev Neurosci. 1992; 15:139-65. PMID: 1575440.
      View in: PubMed
    279. Lipkin SM, Rosenfeld MG, Glass CK. Regulation of gene expression by thyroid hormones and retinoic acid. Genet Eng (N Y). 1992; 14:185-209. PMID: 1369379.
      View in: PubMed
    280. Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Näär AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG. RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell. 1991 Dec 20; 67(6):1251-66. PMID: 1662118.
      View in: PubMed
    281. Chang CP, Kao JP, Lazar CS, Walsh BJ, Wells A, Wiley HS, Gill GN, Rosenfeld MG. Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor. J Biol Chem. 1991 Dec 05; 266(34):23467-70. PMID: 1744139.
      View in: PubMed
    282. Drolet DW, Scully KM, Simmons DM, Wegner M, Chu KT, Swanson LW, Rosenfeld MG. TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. Genes Dev. 1991 Oct; 5(10):1739-53. PMID: 1916262.
      View in: PubMed
    283. Kapiloff MS, Farkash Y, Wegner M, Rosenfeld MG. Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements. Science. 1991 Aug 16; 253(5021):786-9. PMID: 1652153.
      View in: PubMed
    284. He X, Rosenfeld MG. Mechanisms of complex transcriptional regulation: implications for brain development. Neuron. 1991 Aug; 7(2):183-96. PMID: 1873026.
      View in: PubMed
    285. Welsh JB, Gill GN, Rosenfeld MG, Wells A. A negative feedback loop attenuates EGF-induced morphological changes. J Cell Biol. 1991 Aug; 114(3):533-43. PMID: 1860884.
      View in: PubMed
    286. Voss JW, Yao TP, Rosenfeld MG. Alternative translation initiation site usage results in two structurally distinct forms of Pit-1. J Biol Chem. 1991 Jul 15; 266(20):12832-5. PMID: 2071572.
      View in: PubMed
    287. Voss JW, Wilson L, Rosenfeld MG. POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 1991 Jul; 5(7):1309-20. PMID: 2065979.
      View in: PubMed
    288. Näär AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG. The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell. 1991 Jun 28; 65(7):1267-79. PMID: 1648451.
      View in: PubMed
    289. Rosenfeld MG. POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev. 1991 Jun; 5(6):897-907. PMID: 2044958.
      View in: PubMed
    290. Crenshaw EB, Ryan A, Dillon SR, Kalla K, Rosenfeld MG. Wocko, a neurological mutant generated in a transgenic mouse pedigree. J Neurosci. 1991 Jun; 11(6):1524-30. PMID: 1646293.
      View in: PubMed
    291. Kapiloff MS, Mathis JM, Nelson CA, Lin CR, Rosenfeld MG. Calcium/calmodulin-dependent protein kinase mediates a pathway for transcriptional regulation. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3710-4. PMID: 1850836.
      View in: PubMed
    292. Treacy MN, He X, Rosenfeld MG. I-POU: a POU-domain protein that inhibits neuron-specific gene activation. Nature. 1991 Apr 18; 350(6319):577-84. PMID: 1673230.
      View in: PubMed
    293. Carpenter CD, Ingraham HA, Cochet C, Walton GM, Lazar CS, Sowadski JM, Rosenfeld MG, Gill GN. Structural analysis of the transmembrane domain of the epidermal growth factor receptor. J Biol Chem. 1991 Mar 25; 266(9):5750-5. PMID: 2005111.
      View in: PubMed
    294. He X, Gerrero R, Simmons DM, Park RE, Lin CJ, Swanson LW, Rosenfeld MG. Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. Mol Cell Biol. 1991 Mar; 11(3):1739-44. PMID: 1705013.
      View in: PubMed
    295. Glass CK, Devary OV, Rosenfeld MG. Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor. Cell. 1990 Nov 16; 63(4):729-38. PMID: 2171781.
      View in: PubMed
    296. Li S, Crenshaw EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 1990 Oct 11; 347(6293):528-33. PMID: 1977085.
      View in: PubMed
    297. Holloway JM, Glass CK, Adler S, Nelson CA, Rosenfeld MG. The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):8160-4. PMID: 2236029.
      View in: PubMed
    298. Ingraham HA, Flynn SE, Voss JW, Albert VR, Kapiloff MS, Wilson L, Rosenfeld MG. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell. 1990 Jun 15; 61(6):1021-33. PMID: 2350782.
      View in: PubMed
    299. Simmons DM, Voss JW, Ingraham HA, Holloway JM, Broide RS, Rosenfeld MG, Swanson LW. Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev. 1990 May; 4(5):695-711. PMID: 2379827.
      View in: PubMed
    300. Franco R, Rosenfeld MG. Hormonally inducible phosphorylation of a nuclear pool of ribosomal protein S6. J Biol Chem. 1990 Mar 15; 265(8):4321-5. PMID: 2106518.
      View in: PubMed
    301. Wells A, Welsh JB, Lazar CS, Wiley HS, Gill GN, Rosenfeld MG. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science. 1990 Feb 23; 247(4945):962-4. PMID: 2305263.
      View in: PubMed
    302. Walton GM, Chen WS, Rosenfeld MG, Gill GN. Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. J Biol Chem. 1990 Jan 25; 265(3):1750-4. PMID: 1688559.
      View in: PubMed
    303. Elsholtz HP, Albert VR, Treacy MN, Rosenfeld MG. A two-base change in a POU factor-binding site switches pituitary-specific to lymphoid-specific gene expression. Genes Dev. 1990 Jan; 4(1):43-51. PMID: 2307370.
      View in: PubMed
    304. Li S, Klein ES, Russo AF, Simmons DM, Rosenfeld MG. Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9778-82. PMID: 2532363.
      View in: PubMed
    305. Glass CK, Lipkin SM, Devary OV, Rosenfeld MG. Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell. 1989 Nov 17; 59(4):697-708. PMID: 2555064.
      View in: PubMed
    306. Chen WS, Lazar CS, Lund KA, Welsh JB, Chang CP, Walton GM, Der CJ, Wiley HS, Gill GN, Rosenfeld MG. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell. 1989 Oct 06; 59(1):33-43. PMID: 2790960.
      View in: PubMed
    307. Emeson RB, Hedjran F, Yeakley JM, Guise JW, Rosenfeld MG. Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature. 1989 Sep 07; 341(6237):76-80. PMID: 2788825.
      View in: PubMed
    308. He X, Treacy MN, Simmons DM, Ingraham HA, Swanson LW, Rosenfeld MG. Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature. 1989 Jul 06; 340(6228):35-41. PMID: 2739723.
      View in: PubMed
    309. Mangalam HJ, Albert VR, Ingraham HA, Kapiloff M, Wilson L, Nelson C, Elsholtz H, Rosenfeld MG. A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally. Genes Dev. 1989 Jul; 3(7):946-58. PMID: 2550324.
      View in: PubMed
    310. Crenshaw EB, Kalla K, Simmons DM, Swanson LW, Rosenfeld MG. Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements. Genes Dev. 1989 Jul; 3(7):959-72. PMID: 2777076.
      View in: PubMed
    311. Ingraham HA, Chen RP, Mangalam HJ, Elsholtz HP, Flynn SE, Lin CR, Simmons DM, Swanson L, Rosenfeld MG. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell. 1988 Nov 04; 55(3):519-29. PMID: 2902928.
      View in: PubMed
    312. Lee EY, Bookstein R, Young LJ, Lin CJ, Rosenfeld MG, Lee WH. Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79. Proc Natl Acad Sci U S A. 1988 Aug; 85(16):6017-21. PMID: 3413073.
      View in: PubMed
    313. Glass CK, Holloway JM, Devary OV, Rosenfeld MG. The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell. 1988 Jul 29; 54(3):313-23. PMID: 3396073.
      View in: PubMed
    314. Lira SA, Crenshaw EB, Glass CK, Swanson LW, Rosenfeld MG. Identification of rat growth hormone genomic sequences targeting pituitary expression in transgenic mice. Proc Natl Acad Sci U S A. 1988 Jul; 85(13):4755-9. PMID: 3387436.
      View in: PubMed
    315. Russo AF, Crenshaw EB, Lira SA, Simmons DM, Swanson LW, Rosenfeld MG. Neuronal expression of chimeric genes in transgenic mice. Neuron. 1988 Jun; 1(4):311-20. PMID: 3078520.
      View in: PubMed
    316. Nelson C, Albert VR, Elsholtz HP, Lu LI, Rosenfeld MG. Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor. Science. 1988 Mar 18; 239(4846):1400-5. PMID: 2831625.
      View in: PubMed
    317. Adler S, Waterman ML, He X, Rosenfeld MG. Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain. Cell. 1988 Mar 11; 52(5):685-95. PMID: 3345568.
      View in: PubMed
    318. Russo AF, Nelson C, Roos BA, Rosenfeld MG. Differential regulation of the coexpressed calcitonin/alpha-CGRP and beta-CGRP neuroendocrine genes. J Biol Chem. 1988 Jan 05; 263(1):5-8. PMID: 3257211.
      View in: PubMed
    319. Rosenfeld MG, Glass CK, Adler S, Crenshaw EB, He X, Lira SA, Elsholtz HP, Mangalam HJ, Holloway JM, Nelson C. Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:545-56. PMID: 3254780.
      View in: PubMed
    320. Gill GN, Rosenfeld MG, Chen WS, Bertics PJ, Lazar CS. Analysis of functional domains in the epidermal growth factor receptor using site-directed mutagenesis. Adv Exp Med Biol. 1988; 234:91-103. PMID: 3063092.
      View in: PubMed
    321. Rosenfeld MG, Crenshaw EB, Lira SA, Swanson L, Borrelli E, Heyman R, Evans RM. Transgenic mice: applications to the study of the nervous system. Annu Rev Neurosci. 1988; 11:353-72. PMID: 3284446.
      View in: PubMed
    322. Gill GN, Chen WS, Lazar CS, Glenney JR, Wiley HS, Ingraham HA, Rosenfeld MG. Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:467-76. PMID: 3254778.
      View in: PubMed
    323. Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG. A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature. 1987 Oct 22-28; 329(6141):738-41. PMID: 3313046.
      View in: PubMed