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Miles Wilkinson

Title(s)Professor, Reproductive Medicine
SchoolHealth Sciences
Phone858-822-4819
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    Collapse Research 
    Collapse Research Activities and Funding
    The Role of NMD in Embryonic Development
    NIH/NICHD R01HD093846Jul 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Spermatogonial Stem Cell Establishment
    NIH/NIGMS R01GM119128May 1, 2016 - Apr 30, 2020
    Role: Principal Investigator
    Cisplatin-induced epigenomic modifications in male germ cells
    NIH/NICHD R01HD082065Dec 1, 2015 - Nov 30, 2017
    Role: Principal Investigator
    The Role of NMD in Olfactory Neurogenesis
    NIH/NIGMS R01GM111838Jul 10, 2014 - Apr 30, 2018
    Role: Principal Investigator
    Androgen-Dependent Rhox Homeobox Genes
    NIH/NICHD R01HD053808May 7, 2007 - Mar 31, 2013
    Role: Principal Investigator
    Conditional Knockout of WT1 in Sertoli Cells In Vivo
    NIH/NICHD R01HD042714Mar 1, 2003 - Feb 28, 2010
    Role: Principal Investigator
    Regulation of RNA Surveillance
    NIH/NIGMS R01GM058595Jan 1, 1999 - Jun 30, 2013
    Role: Principal Investigator
    Regulation and Function of the Rhox5 Homeobox Gene
    NIH/NICHD R01HD045595May 1, 1991 - May 31, 2014
    Role: Principal Investigator
    PEM HOMEOBOX GENE
    NIH/NCI R01CA078023May 1, 1991 - Jan 31, 2004
    Role: Principal Investigator
    PEM-A NOVEL GENE EXPRESSED IN EMBRYOS AND TUMOR CELLS
    NIH/NICHD R01HD027233May 1, 1991 - Dec 31, 1997
    Role: Principal Investigator
    REGULATION OF T-CELL RECEPTOR EXPRESSION
    NIH/NIGMS R01GM039586Feb 1, 1988 - Aug 31, 1999
    Role: Principal Investigator
    REGULATION OF T-CELL RECEPTOR GENE EXPRESSION
    NIH/NIGMS R29GM039586Feb 1, 1988 - Jan 31, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wilkinson MF. Genetic paradox explained by nonsense. Nature. 2019 Apr; 568(7751):179-180. PMID: 30962551.
      View in: PubMed
    2. Tan K, Wilkinson MF. Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass. Cell Stem Cell. 2019 Feb 07; 24(2):201-203. PMID: 30735645.
      View in: PubMed
    3. Sohni A, Tan K, Song HW, Burow D, de Rooij DG, Laurent L, Hsieh TC, Rabah R, Hammoud SS, Vicini E, Wilkinson MF. The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Rep. 2019 Feb 05; 26(6):1501-1517.e4. PMID: 30726734.
      View in: PubMed
    4. Wilkinson MF, Cook-Andersen H. Nonsense shielding: protecting RNA from decay leads to cancer. EMBO J. 2019 Feb 01; 38(3). PMID: 30679197.
      View in: PubMed
    5. Ramaiah M, Tan K, Plank TM, Song HW, Dumdie JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. EMBO Rep. 2019 Feb; 20(2). PMID: 30573526.
      View in: PubMed
    6. Jaffrey SR, Wilkinson MF. Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease. Nat Rev Neurosci. 2018 Dec; 19(12):715-728. PMID: 30410025.
      View in: PubMed
    7. Dumdie JN, Cho K, Ramaiah M, Skarbrevik D, Mora-Castilla S, Stumpo DJ, Lykke-Andersen J, Laurent LC, Blackshear PJ, Wilkinson MF, Cook-Andersen H. Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2. Dev Cell. 2018 02 05; 44(3):392-402.e7. PMID: 29408237.
      View in: PubMed
    8. Gao Z, Wilkinson M. An RNA decay factor wears a new coat: UPF3B modulates translation termination. F1000Res. 2017; 6:2159. PMID: 29333258.
      View in: PubMed
    9. M Plank TD, Wilkinson MF. RNA Decay Factor UPF1 Promotes Protein Decay: A Hidden Talent. Bioessays. 2018 Jan; 40(1). PMID: 29236296.
      View in: PubMed
    10. Goetz AE, Wilkinson M. Erratum to: Stress and the nonsense-mediated RNA decay pathway. Cell Mol Life Sci. 2017 Nov; 74(21):4047. PMID: 28905073.
      View in: PubMed
    11. Huang L, Shum EY, Jones SH, Lou CH, Dumdie J, Kim H, Roberts AJ, Jolly LA, Espinoza JL, Skarbrevik DM, Phan MH, Cook-Andersen H, Swerdlow NR, Gecz J, Wilkinson MF. A Upf3b-mutant mouse model with behavioral and neurogenesis defects. Mol Psychiatry. 2018 Aug; 23(8):1773-1786. PMID: 28948974.
      View in: PubMed
    12. Goetz AE, Wilkinson M. Stress and the nonsense-mediated RNA decay pathway. Cell Mol Life Sci. 2017 10; 74(19):3509-3531. PMID: 28503708.
      View in: PubMed
    13. Jones SH, Wilkinson M. RNA decay, evolution, and the testis. RNA Biol. 2017 02; 14(2):146-155. PMID: 27911186.
      View in: PubMed
    14. Borgmann J, Tüttelmann F, Dworniczak B, Röpke A, Song HW, Kliesch S, Wilkinson MF, Laurentino S, Gromoll J. The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men. Hum Mol Genet. 2016 11 15; 25(22):4898-4910. PMID: 28171660.
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    15. Song HW, Bettegowda A, Lake BB, Zhao AH, Skarbrevik D, Babajanian E, Sukhwani M, Shum EY, Phan MH, Plank TM, Richardson ME, Ramaiah M, Sridhar V, de Rooij DG, Orwig KE, Zhang K, Wilkinson MF. The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Cell Rep. 2016 09 27; 17(1):149-164. PMID: 27681428.
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    16. Lu J, Plank TD, Su F, Shi X, Liu C, Ji Y, Li S, Huynh A, Shi C, Zhu B, Yang G, Wu Y, Wilkinson MF, Lu Y. The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors. J Clin Invest. 2016 08 01; 126(8):3058-62. PMID: 27348585.
      View in: PubMed
    17. Lou CH, Dumdie J, Goetz A, Shum EY, Brafman D, Liao X, Mora-Castilla S, Ramaiah M, Cook-Andersen H, Laurent L, Wilkinson MF. Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. Stem Cell Reports. 2016 06 14; 6(6):844-857. PMID: 27304915.
      View in: PubMed
    18. Shum EY, Jones SH, Shao A, Dumdie J, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson MF. The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell. 2016 Apr 07; 165(2):382-95. PMID: 27040500.
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    19. Cook-Andersen H, Wilkinson MF. Molecular biology: Splicing does the two-step. Nature. 2015 May 21; 521(7552):300-1. PMID: 25970243; PMCID: PMC4809257.
    20. Shum EY, Espinoza JL, Ramaiah M, Wilkinson MF. Identification of novel post-transcriptional features in olfactory receptor family mRNAs. Nucleic Acids Res. 2015 Oct 30; 43(19):9314-26. PMID: 25908788.
      View in: PubMed
    21. Lou CH, Shum EY, Wilkinson MF. RNA degradation drives stem cell differentiation. EMBO J. 2015 Jun 12; 34(12):1606-8. PMID: 25899816; PMCID: PMC4475395.
    22. Wilkinson MF. Evidence that DNA methylation engenders dynamic gene regulation. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):E2116. PMID: 25848065.
      View in: PubMed
    23. Karam R, Lou CH, Kroeger H, Huang L, Lin JH, Wilkinson MF. The unfolded protein response is shaped by the NMD pathway. EMBO Rep. 2015 May; 16(5):599-609. PMID: 25807986; PMCID: PMC4428047.
    24. Song HW, Bettegowda A, Oliver D, Yan W, Phan MH, de Rooij DG, Corbett MA, Wilkinson MF. shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects. PLoS One. 2015; 10(3):e0118549. PMID: 25790000; PMCID: PMC4366048.
    25. Shao A, Wilkinson MF. Suppressing nonsense--a surprising function for 5-azacytidine. EMBO Mol Med. 2014 Dec; 6(12):1518-20. PMID: 25378479; PMCID: PMC4287971.
    26. Rao MK, Matsumoto Y, Richardson ME, Panneerdoss S, Bhardwaj A, Ward JM, Shanker S, Bettegowda A, Wilkinson MF. Hormone-induced and DNA demethylation-induced relief of a tissue-specific and developmentally regulated block in transcriptional elongation. J Biol Chem. 2014 Dec 19; 289(51):35087-101. PMID: 25331959; PMCID: PMC4271199.
    27. Liu C, Karam R, Zhou Y, Su F, Ji Y, Li G, Xu G, Lu L, Wang C, Song M, Zhu J, Wang Y, Zhao Y, Foo WC, Zuo M, Valasek MA, Javle M, Wilkinson MF, Lu Y. The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. Nat Med. 2014 Jun; 20(6):596-8. PMID: 24859531; PMCID: PMC4048332.
    28. De Gendt K, Verhoeven G, Amieux PS, Wilkinson MF. Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach. Mol Endocrinol. 2014 Apr; 28(4):575-91. PMID: 24606126; PMCID: PMC3968405.
    29. Song HW, Wilkinson MF. Transcriptional control of spermatogonial maintenance and differentiation. Semin Cell Dev Biol. 2014 Jun; 30:14-26. PMID: 24560784; PMCID: PMC4043860.
    30. Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF. Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. Cell Rep. 2014 Feb 27; 6(4):748-64. PMID: 24529710.
      View in: PubMed
    31. Nguyen LS, Wilkinson MF, Gecz J. Nonsense-mediated mRNA decay: inter-individual variability and human disease. Neurosci Biobehav Rev. 2014 Oct; 46 Pt 2:175-86. PMID: 24239855.
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    32. Lasalde C, Rivera AV, León AJ, González-Feliciano JA, Estrella LA, Rodríguez-Cruz EN, Correa ME, Cajigas IJ, Bracho DP, Vega IE, Wilkinson MF, González CI. Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res. 2014 Feb; 42(3):1916-29. PMID: 24198248; PMCID: PMC3919615.
    33. MacLean JA, Hu Z, Welborn JP, Song HW, Rao MK, Wayne CM, Wilkinson MF. The RHOX homeodomain proteins regulate the expression of insulin and other metabolic regulators in the testis. J Biol Chem. 2013 Nov 29; 288(48):34809-25. PMID: 24121513.
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    34. Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK. Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol. 2013 Dec; 31(12):1137-42. PMID: 24108092; PMCID: PMC3858462.
    35. Richardson ME, Bleiziffer A, Tüttelmann F, Gromoll J, Wilkinson MF. Epigenetic regulation of the RHOX homeobox gene cluster and its association with human male infertility. Hum Mol Genet. 2014 Jan 01; 23(1):12-23. PMID: 23943794; PMCID: PMC3857941.
    36. Karam R, Wengrod J, Gardner LB, Wilkinson MF. Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochim Biophys Acta. 2013 Jun-Jul; 1829(6-7):624-33. PMID: 23500037.
      View in: PubMed
    37. Song HW, Anderson RA, Bayne RA, Gromoll J, Shimasaki S, Chang RJ, Parast MM, Laurent LC, de Rooij DG, Hsieh TC, Wilkinson MF. The RHOX homeobox gene cluster is selectively expressed in human oocytes and male germ cells. Hum Reprod. 2013 Jun; 28(6):1635-46. PMID: 23482336.
      View in: PubMed
    38. Song HW, Wilkinson MF. In vitro spermatogenesis: A long journey to get tails. Spermatogenesis. 2012 Oct 01; 2(4):238-244. PMID: 23248764.
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    39. Huang L, Wilkinson MF. Regulation of nonsense-mediated mRNA decay. Wiley Interdiscip Rev RNA. 2012 Nov-Dec; 3(6):807-28. PMID: 23027648.
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    40. MacLean JA, Hayashi K, Turner TT, Wilkinson MF. The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis. Biol Reprod. 2012 Jun; 86(6):189. PMID: 22423045.
      View in: PubMed
    41. Song HW, Dann CT, McCarrey JR, Meistrich ML, Cornwall GA, Wilkinson MF. Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction. 2012 May; 143(5):611-24. PMID: 22393026.
      View in: PubMed
    42. Ramaiah M, Shum EY, Wilkinson MF. How to activate a gene: decap its associated noncoding RNA. Mol Cell. 2012 Feb 10; 45(3):271-3. PMID: 22325347; PMCID: PMC4281020.
    43. Bhardwaj A, Song HW, Beildeck M, Kerkhofs S, Castoro R, Shanker S, De Gendt K, Suzuki K, Claessens F, Issa JP, Orgebin-Crist MC, Wilkinson MF. DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis. Mol Endocrinol. 2012 Apr; 26(4):538-49. PMID: 22322598; PMCID: PMC3327359.
    44. Karam R, Wilkinson M. A conserved microRNA/NMD regulatory circuit controls gene expression. RNA Biol. 2012 Jan; 9(1):22-6. PMID: 22258150.
      View in: PubMed
    45. Nguyen LS, Jolly L, Shoubridge C, Chan WK, Huang L, Laumonnier F, Raynaud M, Hackett A, Field M, Rodriguez J, Srivastava AK, Lee Y, Long R, Addington AM, Rapoport JL, Suren S, Hahn CN, Gamble J, Wilkinson MF, Corbett MA, Gecz J. Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability. Mol Psychiatry. 2012 Nov; 17(11):1103-15. PMID: 22182939.
      View in: PubMed
    46. Huang L, Lou CH, Chan W, Shum EY, Shao A, Stone E, Karam R, Song HW, Wilkinson MF. RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD. Mol Cell. 2011 Sep 16; 43(6):950-61. PMID: 21925383; PMCID: PMC4281029.
    47. De Gendt K, Denolet E, Willems A, Daniels VW, Clinckemalie L, Denayer S, Wilkinson MF, Claessens F, Swinnen JV, Verhoeven G. Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells. Biol Reprod. 2011 Nov; 85(5):934-45. PMID: 21734264.
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    48. Bruno IG, Karam R, Huang L, Bhardwaj A, Lou CH, Shum EY, Song HW, Corbett MA, Gifford WD, Gecz J, Pfaff SL, Wilkinson MF. Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell. 2011 May 20; 42(4):500-10. PMID: 21596314; PMCID: PMC3123134.
    49. Maclean JA, Bettegowda A, Kim BJ, Lou CH, Yang SM, Bhardwaj A, Shanker S, Hu Z, Fan Y, Eckardt S, McLaughlin KJ, Skoultchi AI, Wilkinson MF. The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation. Mol Cell Biol. 2011 Mar; 31(6):1275-87. PMID: 21245380; PMCID: PMC3067900.
    50. Bettegowda A, Wilkinson MF. Transcription and post-transcriptional regulation of spermatogenesis. Philos Trans R Soc Lond B Biol Sci. 2010 May 27; 365(1546):1637-51. PMID: 20403875.
      View in: PubMed
    51. MacLean JA, Wilkinson MF. The Rhox genes. Reproduction. 2010 Aug; 140(2):195-213. PMID: 20430877.
      View in: PubMed
    52. Imam JS, Gudikote JP, Chan WK, Wilkinson MF. Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption. Nucleic Acids Res. 2010 Mar; 38(5):1559-74. PMID: 20007599; PMCID: PMC2836556.
    53. Hu Z, Dandekar D, O'Shaughnessy PJ, De Gendt K, Verhoeven G, Wilkinson MF. Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes. Mol Endocrinol. 2010 Jan; 24(1):60-75. PMID: 19901196; PMCID: PMC2802895.
    54. Estrella LA, Wilkinson MF, González CI. The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae. J Mol Biol. 2009 Dec 04; 394(3):410-22. PMID: 19733178; PMCID: PMC2783964.
    55. Chan WK, Bhalla AD, Le Hir H, Nguyen LS, Huang L, Gécz J, Wilkinson MF. A UPF3-mediated regulatory switch that maintains RNA surveillance. Nat Struct Mol Biol. 2009 Jul; 16(7):747-53. PMID: 19503078.
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    56. Zhu K, Chan W, Heymach J, Wilkinson M, McConkey DJ. Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Res. 2009 Mar 01; 69(5):1836-43. PMID: 19244104; PMCID: PMC4188393.
    57. Bhalla AD, Gudikote JP, Wang J, Chan WK, Chang YF, Olivas OR, Wilkinson MF. Nonsense codons trigger an RNA partitioning shift. J Biol Chem. 2009 Feb 13; 284(7):4062-72. PMID: 19091751; PMCID: PMC2640978.
    58. Shanker S, Hu Z, Wilkinson MF. Epigenetic regulation and downstream targets of the Rhox5 homeobox gene. Int J Androl. 2008 Sep; 31(5):462-70. PMID: 18637153.
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    59. Karam R, Carvalho J, Bruno I, Graziadio C, Senz J, Huntsman D, Carneiro F, Seruca R, Wilkinson MF, Oliveira C. The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. Oncogene. 2008 Jul 10; 27(30):4255-60. PMID: 18427545.
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    60. Shyu AB, Wilkinson MF, van Hoof A. Messenger RNA regulation: to translate or to degrade. EMBO J. 2008 Feb 06; 27(3):471-81. PMID: 18256698; PMCID: PMC2241649.
    61. Bhardwaj A, Rao MK, Kaur R, Buttigieg MR, Wilkinson MF. GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells. Mol Cell Biol. 2008 Apr; 28(7):2138-53. PMID: 18212046.
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    62. Hu Z, Shanker S, MacLean JA, Ackerman SL, Wilkinson MF. The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c. J Biol Chem. 2008 Feb 15; 283(7):3866-76. PMID: 18077458.
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    63. Hu Z, MacLean JA, Bhardwaj A, Wilkinson MF. Regulation and function of the Rhox5 homeobox gene. Ann N Y Acad Sci. 2007 Dec; 1120:72-83. PMID: 18184911.
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    64. Chang YF, Chan WK, Imam JS, Wilkinson MF. Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. J Biol Chem. 2007 Oct 12; 282(41):29738-47. PMID: 17693403.
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    65. Chan WK, Huang L, Gudikote JP, Chang YF, Imam JS, MacLean JA, Wilkinson MF. An alternative branch of the nonsense-mediated decay pathway. EMBO J. 2007 Apr 04; 26(7):1820-30. PMID: 17363904.
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    66. Chang YF, Imam JS, Wilkinson MF. The nonsense-mediated decay RNA surveillance pathway. Annu Rev Biochem. 2007; 76:51-74. PMID: 17352659.
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    67. Bruno I, Wilkinson MF. P-bodies react to stress and nonsense. Cell. 2006 Jun 16; 125(6):1036-8. PMID: 16777595.
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    68. Wang W, Cajigas IJ, Peltz SW, Wilkinson MF, González CI. Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay. Mol Cell Biol. 2006 May; 26(9):3390-400. PMID: 16611983; PMCID: PMC1447418.
    69. MacLean JA, Lorenzetti D, Hu Z, Salerno WJ, Miller J, Wilkinson MF. Rhox homeobox gene cluster: recent duplication of three family members. Genesis. 2006 Mar; 44(3):122-9. PMID: 16496311.
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    70. Rao MK, Pham J, Imam JS, MacLean JA, Murali D, Furuta Y, Sinha-Hikim AP, Wilkinson MF. Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev. 2006 Jan 15; 20(2):147-52. PMID: 16418481; PMCID: PMC1356106.
    71. Rao MK, Wilkinson MF. Tissue-specific and cell type-specific RNA interference in vivo. Nat Protoc. 2006; 1(3):1494-501. PMID: 17406440.
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    72. Gudikote JP, Imam JS, Garcia RF, Wilkinson MF. RNA splicing promotes translation and RNA surveillance. Nat Struct Mol Biol. 2005 Sep; 12(9):801-9. PMID: 16116435.
      View in: PubMed
    73. MacLean JA, Rao MK, Doyle KM, Richards JS, Wilkinson MF. Regulation of the Rhox5 homeobox gene in primary granulosa cells: preovulatory expression and dependence on SP1/SP3 and GABP. Biol Reprod. 2005 Dec; 73(6):1126-34. PMID: 16093360.
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    74. Sims-Mourtada JC, Bruce S, McKeller MR, Rangel R, Guzman-Rojas L, Cain K, Lopez C, Zimonjic DB, Popescu NC, Gordon J, Wilkinson MF, Martinez-Valdez H. The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation. DNA Cell Biol. 2005 May; 24(5):325-38. PMID: 15869410.
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    75. Bhardwaj A, Wilkinson MF. A metabolic enzyme doing double duty as a transcription factor. Bioessays. 2005 May; 27(5):467-71. PMID: 15832388.
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    76. Wilkinson MF. A new function for nonsense-mediated mRNA-decay factors. Trends Genet. 2005 Mar; 21(3):143-8. PMID: 15734573.
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    77. Maclean JA, Chen MA, Wayne CM, Bruce SR, Rao M, Meistrich ML, Macleod C, Wilkinson MF. Rhox: a new homeobox gene cluster. Cell. 2005 Feb 11; 120(3):369-82. PMID: 15707895.
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    78. Li S, Wilkinson M, Xia X, David M, Xu L, Purkel-Sutton A, Bhardwaj A. Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA. Mol Ther. 2005 Jan; 11(1):112-9. PMID: 15585412.
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    79. Maclean JA, Wilkinson MF. Gene regulation in spermatogenesis. Curr Top Dev Biol. 2005; 71:131-97. PMID: 16344105.
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    80. Inoue K, Khajavi M, Ohyama T, Hirabayashi S, Wilson J, Reggin JD, Mancias P, Butler IJ, Wilkinson MF, Wegner M, Lupski JR. Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nat Genet. 2004 Apr; 36(4):361-9. PMID: 15004559.
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    81. Wilkinson MF. The cycle of nonsense. Mol Cell. 2003 Nov; 12(5):1059-61. PMID: 14636563.
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    82. Rao MK, Wayne CM, Meistrich ML, Wilkinson MF. Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. Mol Endocrinol. 2003 Feb; 17(2):223-33. PMID: 12554750.
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    83. Wayne CM, Sutton K, Wilkinson MF. Expression of the pem homeobox gene in Sertoli cells increases the frequency of adjacent germ cells with deoxyribonucleic acid strand breaks. Endocrinology. 2002 Dec; 143(12):4875-85. PMID: 12446615.
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    84. Wayne CM, MacLean JA, Cornwall G, Wilkinson MF. Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis. Gene. 2002 Nov 13; 301(1-2):1-11. PMID: 12490318.
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    85. Wang J, Chang YF, Hamilton JI, Wilkinson MF. Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay. Mol Cell. 2002 Oct; 10(4):951-7. PMID: 12419238.
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    86. Rao MK, Wayne CM, Wilkinson MF. Pem homeobox gene regulatory sequences that direct androgen-dependent developmentally regulated gene expression in different subregions of the epididymis. J Biol Chem. 2002 Dec 13; 277(50):48771-8. PMID: 12351657.
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    87. Wang J, Hamilton JI, Carter MS, Li S, Wilkinson MF. Alternatively spliced TCR mRNA induced by disruption of reading frame. Science. 2002 Jul 05; 297(5578):108-10. PMID: 12098701.
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    88. Bühler M, Wilkinson MF, Mühlemann O. Intranuclear degradation of nonsense codon-containing mRNA. EMBO Rep. 2002 Jul; 3(7):646-51. PMID: 12101097; PMCID: PMC1084183.
    89. Wilkinson MF, Shyu AB. RNA surveillance by nuclear scanning? Nat Cell Biol. 2002 Jun; 4(6):E144-7. PMID: 12042827.
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    90. Rao MK, Maiti S, Ananthaswamy HN, Wilkinson MF. A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types. J Biol Chem. 2002 Jul 19; 277(29):26036-45. PMID: 11986330.
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    91. Wang J, Vock VM, Li S, Olivas OR, Wilkinson MF. A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation. J Biol Chem. 2002 May 24; 277(21):18489-93. PMID: 11889124.
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    92. Wang J, Han Y, Liang S, Wilkinson MF. Catalytic antibody therapy against the insecticide carbaryl. Biochem Biophys Res Commun. 2002 Mar 01; 291(3):605-10. PMID: 11855832.
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    93. Wang J, Gudikote JP, Olivas OR, Wilkinson MF. Boundary-independent polar nonsense-mediated decay. EMBO Rep. 2002 Mar; 3(3):274-9. PMID: 11850396; PMCID: PMC1084009.
    94. Gudikote JP, Wilkinson MF. T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts. EMBO J. 2002 Jan 15; 21(1-2):125-34. PMID: 11782432; PMCID: PMC125808.
    95. Wang J, Han Y, Wilkinson MF. An active immunization approach to generate protective catalytic antibodies. Biochem J. 2001 Nov 15; 360(Pt 1):151-7. PMID: 11696002.
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