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Alysson Muotri

Title(s)Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thought, cultural learning and consciousness. From such dynamic complexity emerged extraordinary technological and artistic masterpieces in a relatively short cultural history. Moreover, brain complexity has a creative purpose. Understanding what produces neuronal diversification during brain development has been a longstanding challenge for neuroscientists and may bring insights into the evolution of human cognition.
    The Muotri lab explores mobile elements as generators of diversity during neuronal differentiation. These mobile elements may be part of a conserved genetic core process responsible for evoking facilitated complex non-random phenotypical variation upon which selection may act. The lab uses animal models, neural stem cells, human and other primates’ pluripotent cells and several molecular tools to investigate fundamental mechanisms of brain development, evolution and neural disorders, including Autism Spectrum Disorders.

    Research Focus Areas:

  • Developmental Biology

  • DNA Replication and Repair

  • Genetics and Genomics

  • Gene Expression and Regulation

  • Neurodevelopment and Neurodegenerative Disease

  • Stem Cell Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Molecular neuroanatomy of anorexia nervosa. Sci Rep. 2020 Jul 10; 10(1):11411. Howard D, Negraes P, Voineskos AN, Kaplan AS, Muotri AR, Duvvuri V, French L. PMID: 32651428.
      View in: PubMed   Mentions:    Fields:    
    2. Brainstem Organoids From Human Pluripotent Stem Cells. Front Neurosci. 2020; 14:538. Eura N, Matsui TK, Luginbühl J, Matsubayashi M, Nanaura H, Shiota T, Kinugawa K, Iguchi N, Kiriyama T, Zheng C, Kouno T, Lan YJ, Kongpracha P, Wiriyasermkul P, Sakaguchi YM, Nagata R, Komeda T, Morikawa N, Kitayoshi F, Jong M, Kobashigawa S, Nakanishi M, Hasegawa M, Saito Y, Shiromizu T, Nishimura Y, Kasai T, Takeda M, Kobayashi H, Inagaki Y, Tanaka Y, Makinodan M, Kishimoto T, Kuniyasu H, Nagamori S, Muotri AR, Shin JW, Sugie K, Mori E. PMID: 32670003.
      View in: PubMed   Mentions:
    3. Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. Cell Res. 2020 Oct; 30(10):833-853. Tang M, Xie Q, Gimple RC, Zhong Z, Tam T, Tian J, Kidwell RL, Wu Q, Prager BC, Qiu Z, Yu A, Zhu Z, Mesci P, Jing H, Schimelman J, Wang P, Lee D, Lorenzini MH, Dixit D, Zhao L, Bhargava S, Miller TE, Wan X, Tang J, Sun B, Cravatt BF, Muotri AR, Chen S, Rich JN. PMID: 32499560.
      View in: PubMed   Mentions:    Fields:    
    4. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin avß5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038.
      View in: PubMed   Mentions: 5     Fields:    
    5. Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. Sci Rep. 2019 12 17; 9(1):19291. Shiga Y, Shiga A, Mesci P, Kwon H, Brifault C, Kim JH, Jeziorski JJ, Nasamran C, Ohtori S, Muotri AR, Gonias SL, Campana WM. PMID: 31848365.
      View in: PubMed   Mentions:    Fields:    
    6. Getting to the Cores of Autism. Cell. 2019 09 05; 178(6):1287-1298. Iakoucheva LM, Muotri AR, Sebat J. PMID: 31491383.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    7. Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. Physiology (Bethesda). 2019 09 01; 34(5):365-375. Adams JW, Cugola FR, Muotri AR. PMID: 31389776.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    8. Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. Cell Stem Cell. 2019 10 03; 25(4):558-569.e7. Trujillo CA, Gao R, Negraes PD, Gu J, Buchanan J, Preissl S, Wang A, Wu W, Haddad GG, Chaim IA, Domissy A, Vandenberghe M, Devor A, Yeo GW, Voytek B, Muotri AR. PMID: 31474560.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    9. Transposable Elements, Inflammation, and Neurological Disease. Front Neurol. 2019; 10:894. Saleh A, Macia A, Muotri AR. PMID: 31481926.
      View in: PubMed   Mentions:
    10. Exosomes regulate neurogenesis and circuit assembly. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):16086-16094. Sharma P, Mesci P, Carromeu C, McClatchy DR, Schiapparelli L, Yates JR, Muotri AR, Cline HT. PMID: 31320591.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    11. Altered Gene Expression of Thyroid Hormone Transporters and Deiodinases in iPS MeCP2-Knockout Cells-Derived Neurons. Mol Neurobiol. 2019 Dec; 56(12):8277-8295. de Souza JS, Ferreira DR, Herai R, Carromeu C, Torres LB, Araujo BHS, Cugola F, Maciel RMB, Muotri AR, Giannocco G. PMID: 31214863.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Brain organoids and insights on human evolution. F1000Res. 2019; 8. Muotri AR. PMID: 31275562.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Brain organoids as a model system for human neurodevelopment and disease. Semin Cell Dev Biol. 2019 11; 95:93-97. Setia H, Muotri AR. PMID: 30904636.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    14. Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. PLoS One. 2019; 14(2):e0212553. Kim JJ, Savas JN, Miller MT, Hu X, Carromeu C, Lavallée-Adam M, Freitas BCG, Muotri AR, Yates JR, Ghosh A. PMID: 30789962.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 2019 02 07; 8. Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH. PMID: 30730291.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019 01 29; 26(5):1189-1202.e6. Ward JM, Stoyas CA, Switonski PM, Ichou F, Fan W, Collins B, Wall CE, Adanyeguh I, Niu C, Sopher BL, Kinoshita C, Morrison RS, Durr A, Muotri AR, Evans RM, Mochel F, La Spada AR. PMID: 30699348.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    17. Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice. Transl Psychiatry. 2019 01 17; 9(1):24. Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR. PMID: 30655503.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Brain Organoids and the Study of Neurodevelopment. Trends Mol Med. 2018 12; 24(12):982-990. Trujillo CA, Muotri AR. PMID: 30377071.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    19. Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. EMBO J. 2018 12 14; 37(24). Baltussen LL, Negraes PD, Silvestre M, Claxton S, Moeskops M, Christodoulou E, Flynn HR, Snijders AP, Muotri AR, Ultanir SK. PMID: 30266824.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Direct Generation of Human Cortical Organoids from Primary Cells. Stem Cells Dev. 2018 11 15; 27(22):1549-1556. Schukking M, Miranda HC, Trujillo CA, Negraes PD, Muotri AR. PMID: 30142987.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Frequency and association of mitochondrial genetic variants with neurological disorders. Mitochondrion. 2019 05; 46:345-360. Cruz ACP, Ferrasa A, Muotri AR, Herai RH. PMID: 30218715.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Author Correction: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2018 Jul; 21(7):1016. Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 29703932.
      View in: PubMed   Mentions: 2     Fields:    
    23. Author Correction: Blocking Zika virus vertical transmission. Sci Rep. 2018 Jun 05; 8(1):8794. Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29867187.
      View in: PubMed   Mentions: 1     Fields:    
    24. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Sci Transl Med. 2018 05 09; 10(440). Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud AN, Marsala S, Kafka J, Miyanohara A, Kato T, Tadokoro T, Hefferan MP, Kamizato K, Yoshizumi T, Juhas S, Juhasova J, Ho CS, Kheradmand T, Chen P, Bohaciakova D, Hruska-Plochan M, Todd AJ, Driscoll SP, Glenn TD, Pfaff SL, Klima J, Ciacci J, Curtis E, Gage FH, Bui J, Yamada K, Muotri AR, Marsala M. PMID: 29743351.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    25. Paternally inherited cis-regulatory structural variants are associated with autism. Science. 2018 04 20; 360(6386):327-331. Brandler WM, Antaki D, Gujral M, Kleiber ML, Whitney J, Maile MS, Hong O, Chapman TR, Tan S, Tandon P, Pang T, Tang SC, Vaux KK, Yang Y, Harrington E, Juul S, Turner DJ, Thiruvahindrapuram B, Kaur G, Wang Z, Kingsmore SF, Gleeson JG, Bisson D, Kakaradov B, Telenti A, Venter JC, Corominas R, Toma C, Cormand B, Rueda I, Guijarro S, Messer KS, Nievergelt CM, Arranz MJ, Courchesne E, Pierce K, Muotri AR, Iakoucheva LM, Hervas A, Scherer SW, Corsello C, Sebat J. PMID: 29674594.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    26. Autism spectrum disorders: Challenges and perspectives. Dev Neurobiol. 2018 05; 78(5):431-433. Muotri AR. PMID: 29516662.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    27. Genetic variations on SETD5 underlying autistic conditions. Dev Neurobiol. 2018 05; 78(5):500-518. Fernandes IR, Cruz ACP, Ferrasa A, Phan D, Herai RH, Muotri AR. PMID: 29484850.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    28. Blocking Zika virus vertical transmission. Sci Rep. 2018 01 19; 8(1):1218. Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29352135.
      View in: PubMed   Mentions: 9     Fields:    
    29. The contribution of GTF2I haploinsufficiency to Williams syndrome. Mol Cell Probes. 2018 08; 40:45-51. Chailangkarn T, Noree C, Muotri AR. PMID: 29305905.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    30. Modeling neuro-immune interactions during Zika virus infection. Hum Mol Genet. 2018 01 01; 27(1):41-52. Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, de A Zanotto PM, Beltrão-Braga PCB, Nizet V, Muotri AR. PMID: 29048558.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    31. LINE-1 retrotransposons in healthy and diseased human brain. Dev Neurobiol. 2018 May; 78(5):434-455. Suarez NA, Macia A, Muotri AR. PMID: 29239145.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    32. Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. Dis Model Mech. 2017 12 19; 10(12):1439-1451. van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D. PMID: 28993314.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    33. Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. Sci Rep. 2017 Nov 17; 7(1):15771. Shiryaev SA, Mesci P, Pinto A, Fernandes I, Sheets N, Shresta S, Farhy C, Huang CT, Strongin AY, Muotri AR, Terskikh AV. PMID: 29150641.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    34. The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells. Biochem Biophys Res Commun. 2017 12 16; 494(3-4):504-510. Yoo M, Carromeu C, Kwon O, Muotri A, Schachner M. PMID: 29050935.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    35. Modeling the Interplay Between Neurons and Astrocytes in Autism Using Human Induced Pluripotent Stem Cells. Biol Psychiatry. 2018 04 01; 83(7):569-578. Russo FB, Freitas BC, Pignatari GC, Fernandes IR, Sebat J, Muotri AR, Beltrão-Braga PCB. PMID: 29129319.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    36. Corrigendum: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2017 Sep 28; 20(10):1427. Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 28949329.
      View in: PubMed   Mentions:    Fields:    
    37. Autism spectrum disorders and disease modeling using stem cells. Cell Tissue Res. 2018 01; 371(1):153-160. Brito A, Russo FB, Muotri AR, Beltrão-Braga PCB. PMID: 28918504.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    38. Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. Cell Stem Cell. 2017 09 07; 21(3):319-331.e8. Thomas CA, Tejwani L, Trujillo CA, Negraes PD, Herai RH, Mesci P, Macia A, Crow YJ, Muotri AR. PMID: 28803918.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    39. Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA. Hum Mol Genet. 2017 07 01; 26(13):2590. Herai RH, Negraes PD, Muotri AR. PMID: 28637317.
      View in: PubMed   Mentions:    Fields:    
    40. Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA. Hum Mol Genet. 2017 07 01; 26(13):2472-2479. Herai RH, Negraes PD, Muotri AR. PMID: 28430982.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    41. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5635-E5644. Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W. PMID: 28630288.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    42. Stem cell contributions to neurological disease modeling and personalized medicine. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jan 03; 80(Pt A):54-62. Liang N, Trujillo CA, Negraes PD, Muotri AR, Lameu C, Ulrich H. PMID: 28576415.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    43. Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons. Transl Psychiatry. 2017 03 14; 7(3):e1060. Negraes PD, Cugola FR, Herai RH, Trujillo CA, Cristino AS, Chailangkarn T, Muotri AR, Duvvuri V. PMID: 28291261.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    44. Modeling Williams syndrome with induced pluripotent stem cells. Neurogenesis (Austin). 2017; 4(1):e1283187. Chailangkarn T, Muotri AR. PMID: 28229087.
      View in: PubMed   Mentions:
    45. IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3. Hum Mol Genet. 2017 01 15; 26(2):270-281. de Souza JS, Carromeu C, Torres LB, Araujo BH, Cugola FR, Maciel RM, Muotri AR, Giannocco G. PMID: 28007906.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    46. TRPC Channels and Mental Disorders. Adv Exp Med Biol. 2017; 976:137-148. Griesi-Oliveira K, Suzuki AM, Muotri AR. PMID: 28508319.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    47. Engineered LINE-1 retrotransposition in nondividing human neurons. Genome Res. 2017 03; 27(3):335-348. Macia A, Widmann TJ, Heras SR, Ayllon V, Sanchez L, Benkaddour-Boumzaouad M, Muñoz-Lopez M, Rubio A, Amador-Cubero S, Blanco-Jimenez E, Garcia-Castro J, Menendez P, Ng P, Muotri AR, Goodier JL, Garcia-Perez JL. PMID: 27965292.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    48. Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations. Drug Discov Today. 2017 02; 22(2):327-339. Langley GR, Adcock IM, Busquet F, Crofton KM, Csernok E, Giese C, Heinonen T, Herrmann K, Hofmann-Apitius M, Landesmann B, Marshall LJ, McIvor E, Muotri AR, Noor F, Schutte K, Seidle T, van de Stolpe A, Van Esch H, Willett C, Woszczek G. PMID: 27989722.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    49. The Na+/HCO3- co-transporter is protective during ischemia in astrocytes. Neuroscience. 2016 Dec 17; 339:329-337. Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad GG. PMID: 27717805.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    50. L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2016 12; 19(12):1583-1591. Erwin JA, Paquola AC, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FI, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 27618310.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    51. Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation. J Cell Sci. 2016 09 15; 129(18):3437-48. Pillat MM, Lameu C, Trujillo CA, Glaser T, Cappellari AR, Negraes PD, Battastini AM, Schwindt TT, Muotri AR, Ulrich H. PMID: 27528403.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    52. A human neurodevelopmental model for Williams syndrome. Nature. 2016 08 18; 536(7616):338-43. Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR. PMID: 27509850.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    53. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry. 2017 06; 22(6):820-835. Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR. PMID: 27378147.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    54. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016 06 09; 534(7606):267-71. Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimarães KP, Benazzato C, Almeida N, Pignatari GC, Romero S, Polonio CM, Cunha I, Freitas CL, Brandão WN, Rossato C, Andrade DG, Faria Dde P, Garcez AT, Buchpigel CA, Braconi CT, Mendes E, Sall AA, Zanotto PM, Peron JP, Muotri AR, Beltrão-Braga PC. PMID: 27279226.
      View in: PubMed   Mentions: 351     Fields:    Translation:AnimalsCells
    55. Frequency and Complexity of De Novo Structural Mutation in Autism. Am J Hum Genet. 2016 Apr 07; 98(4):667-79. Brandler WM, Antaki D, Gujral M, Noor A, Rosanio G, Chapman TR, Barrera DJ, Lin GN, Malhotra D, Watts AC, Wong LC, Estabillo JA, Gadomski TE, Hong O, Fajardo KV, Bhandari A, Owen R, Baughn M, Yuan J, Solomon T, Moyzis AG, Maile MS, Sanders SJ, Reiner GE, Vaux KK, Strom CM, Zhang K, Muotri AR, Akshoomoff N, Leal SM, Pierce K, Courchesne E, Iakoucheva LM, Corsello C, Sebat J. PMID: 27018473.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    56. Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation. Cell Rep. 2016 Mar 22; 14(11):2554-61. Wang Y, Jones-Tabah J, Chakravarty P, Stewart A, Muotri A, Laposa RR, Svejstrup JQ. PMID: 26972010.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    57. Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):3185-90. Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A. PMID: 26944080.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    58. Modeling autism spectrum disorders with human neurons. Brain Res. 2017 02 01; 1656:49-54. Beltrão-Braga PC, Muotri AR. PMID: 26854137.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    59. XPC deficiency is related to APE1 and OGG1 expression and function. Mutat Res. 2016 Feb-Mar; 784-785:25-33. de Melo JT, de Souza Timoteo AR, Lajus TB, Brandão JA, de Souza-Pinto NC, Menck CF, Campalans A, Radicella JP, Vessoni AT, Muotri AR, Agnez-Lima LF. PMID: 26811994.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    60. Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony. Hum Mol Genet. 2016 Apr 01; 25(7):1271-80. Vessoni AT, Herai RH, Karpiak JV, Leal AM, Trujillo CA, Quinet A, Agnez Lima LF, Menck CF, Muotri AR. PMID: 26755826.
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    61. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):751-6. Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. PMID: 26733678.
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    62. L1 Retrotransposition in Neural Progenitor Cells. Methods Mol Biol. 2016; 1400:157-63. Muotri AR. PMID: 26895053.
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    63. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. 2015 Dec 08; 5(6):933-945. Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. PMID: 26610635.
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    64. Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research. Environ Health Perspect. 2015 Nov; 123(11):A268-72. Langley G, Austin CP, Balapure AK, Birnbaum LS, Bucher JR, Fentem J, Fitzpatrick SC, Fowle JR, Kavlock RJ, Kitano H, Lidbury BA, Muotri AR, Peng SQ, Sakharov D, Seidle T, Trez T, Tonevitsky A, van de Stolpe A, Whelan M, Willett C. PMID: 26523530.
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    65. Neurotoxic Methamphetamine Doses Increase LINE-1 Expression in the Neurogenic Zones of the Adult Rat Brain. Sci Rep. 2015 Oct 14; 5:14356. Moszczynska A, Flack A, Qiu P, Muotri AR, Killinger BA. PMID: 26463126.
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    66. Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome. Hum Mol Genet. 2015 Dec 15; 24(24):6877-85. Melo US, Macedo-Souza LI, Figueiredo T, Muotri AR, Gleeson JG, Coux G, Armas P, Calcaterra NB, Kitajima JP, Amorim S, Olávio TR, Griesi-Oliveira K, Coatti GC, Rocha CR, Martins-Pinheiro M, Menck CF, Zaki MS, Kok F, Zatz M, Santos S. PMID: 26385635.
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    67. Altered neuronal network and rescue in a human MECP2 duplication model. Mol Psychiatry. 2016 Feb; 21(2):178-88. Nageshappa S, Carromeu C, Trujillo CA, Mesci P, Espuny-Camacho I, Pasciuto E, Vanderhaeghen P, Verfaillie CM, Raitano S, Kumar A, Carvalho CM, Bagni C, Ramocki MB, Araujo BH, Torres LB, Lupski JR, Van Esch H, Muotri AR. PMID: 26347316.
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    68. The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. Neurotherapeutics. 2015 Jul; 12(3):534-45. Acab A, Muotri AR. PMID: 25851569.
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    69. Systematic optimization of human pluripotent stem cells media using Design of Experiments. Sci Rep. 2015 May 05; 5:9834. Marinho PA, Chailangkarn T, Muotri AR. PMID: 25940691.
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    70. The Human Model: Changing Focus on Autism Research. Biol Psychiatry. 2016 Apr 15; 79(8):642-9. Muotri AR. PMID: 25861701.
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    71. Altered iPSC-derived neurons' sodium channel properties in subjects with Monge's disease. Neuroscience. 2015 Mar 12; 288:187-99. Zhao HW, Gu XQ, Chailangkarn T, Perkins G, Callacondo D, Appenzeller O, Poulsen O, Zhou D, Muotri AR, Haddad GG. PMID: 25559931.
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    72. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry. 2015 Nov; 20(11):1350-65. Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. PMID: 25385366.
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    73. Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. Nat Neurosci. 2014 Sep; 17(9):1180-9. Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR. PMID: 25108912.
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    74. Fibroblast sources: Where can we get them? Cytotechnology. 2016 Mar; 68(2):223-8. Fernandes IR, Russo FB, Pignatari GC, Evangelinellis MM, Tavolari S, Muotri AR, Beltrão-Braga PC. PMID: 25060709.
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    75. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 2014 Jul 02; 83(1):69-86. Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. PMID: 24991955.
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    76. Micro RNA detection in long-term fixed tissue of cortical glutamatergic pyramidal neurons after targeted laser-capture neuroanatomical microdissection. J Neurosci Methods. 2014 Sep 30; 235:76-82. Herai RR, Stefanacci L, Hrvoj-Mihic B, Chailangkarn T, Hanson K, Semendeferi K, Muotri AR. PMID: 24992573.
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    77. Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies. J Comp Neurol. 2014 Aug 15; 522(12):2784-801. Dolezalova D, Hruska-Plochan M, Bjarkam CR, Sørensen JC, Cunningham M, Weingarten D, Ciacci JD, Juhas S, Juhasova J, Motlik J, Hefferan MP, Hazel T, Johe K, Carromeu C, Muotri A, Bui J, Strnadel J, Marsala M. PMID: 24610493.
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    78. Evolution, development, and plasticity of the human brain: from molecules to bones. Front Hum Neurosci. 2013 Oct 30; 7:707. Hrvoj-Mihic B, Bienvenu T, Stefanacci L, Muotri AR, Semendeferi K. PMID: 24194709.
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    79. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 2013 Nov 28; 503(7477):525-529. Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. PMID: 24153179.
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    80. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Biol Psychiatry. 2014 Jun 15; 75(12):929-35. Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR. PMID: 24041506.
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    81. Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell. 2013 Aug 01; 13(2):246-54. Yoshioka N, Gros E, Li HR, Kumar S, Deacon DC, Maron C, Muotri AR, Chi NC, Fu XD, Yu BD, Dowdy SF. PMID: 23910086.
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    82. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Res. 2013 Sep; 11(2):743-57. Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. PMID: 23759711.
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    83. Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. Neurobiol Learn Mem. 2013 Mar; 101:94-102. Lovatel GA, Elsner VR, Bertoldi K, Vanzella C, Moysés Fdos S, Vizuete A, Spindler C, Cechinel LR, Netto CA, Muotri AR, Siqueira IR. PMID: 23357282.
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    84. In-a-dish: induced pluripotent stem cells as a novel model for human diseases. Cytometry A. 2013 Jan; 83(1):11-7. Beltrão-Braga PC, Pignatari GC, Russo FB, Fernandes IR, Muotri AR. PMID: 23281003.
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    85. Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study. Exp Gerontol. 2013 Feb; 48(2):136-9. Elsner VR, Lovatel GA, Moysés F, Bertoldi K, Spindler C, Cechinel LR, Muotri AR, Siqueira IR. PMID: 23201423.
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    86. Kinin-B2 receptor activity determines the differentiation fate of neural stem cells. J Biol Chem. 2012 Dec 28; 287(53):44046-61. Trujillo CA, Negraes PD, Schwindt TT, Lameu C, Carromeu C, Muotri AR, Pesquero JB, Cerqueira DM, Pillat MM, de Souza HD, Turaça LT, Abreu JG, Ulrich H. PMID: 23132855.
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    87. Stem cells and modeling of autism spectrum disorders. Exp Neurol. 2014 Oct; 260:33-43. Freitas BC, Trujillo CA, Carromeu C, Yusupova M, Herai RH, Muotri AR. PMID: 23036599.
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    88. A quantitative proteomic and transcriptomic comparison of human mesenchymal stem cells from bone marrow and umbilical cord vein. Proteomics. 2012 Aug; 12(17):2607-17. Miranda HC, Herai RH, Thomé CH, Gomes GG, Panepucci RA, Orellana MD, Covas DT, Muotri AR, Greene LJ, Faça VM. PMID: 22778083.
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    89. Modeling neurodevelopmental disorders using human neurons. Curr Opin Neurobiol. 2012 Oct; 22(5):785-90. Chailangkarn T, Acab A, Muotri AR. PMID: 22717528.
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    90. Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome. Hum Mol Genet. 2012 Sep 01; 21(17):3825-34. Andrade LN, Nathanson JL, Yeo GW, Menck CF, Muotri AR. PMID: 22661500.
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    91. What makes each brain unique. Sci Am. 2012 Mar; 306(3):26-31. Gage FH, Muotri AR. PMID: 22375319.
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    92. Autophagy in stem cell maintenance and differentiation. Stem Cells Dev. 2012 Mar 01; 21(4):513-20. Vessoni AT, Muotri AR, Okamoto OK. PMID: 22066548.
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    93. LINE-1: creators of neuronal diversity. Front Biosci (Elite Ed). 2012 Jan 01; 4:1663-8. Thomas CA, Muotri AR. PMID: 22201983.
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    94. LINE-1 retrotransposition in the nervous system. Annu Rev Cell Dev Biol. 2012; 28:555-73. Thomas CA, Paquola AC, Muotri AR. PMID: 23057747.
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    95. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20382-7. Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. PMID: 22159035.
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    96. Cellular reprogramming: recent advances in modeling neurological diseases. J Neurosci. 2011 Nov 09; 31(45):16070-5. Ming GL, Brüstle O, Muotri A, Studer L, Wernig M, Christian KM. PMID: 22072658.
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    97. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum Mol Genet. 2011 Sep 15; 20(18):3642-52. Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M. PMID: 21685205.
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    98. Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro. . 2011 Sep; 301(3):R727-45. Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad GG. PMID: 21677276.
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    99. Feeder-free derivation of induced pluripotent stem cells from human immature dental pulp stem cells. Cell Transplant. 2011; 20(11-12):1707-19. Beltrão-Braga PC, Pignatari GC, Maiorka PC, Oliveira NA, Lizier NF, Wenceslau CV, Miglino MA, Muotri AR, Kerkis I. PMID: 21457612.
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    100. Maintenance and differentiation of neural stem cells. Wiley Interdiscip Rev Syst Biol Med. 2011 Jan-Feb; 3(1):107-14. Massirer KB, Carromeu C, Griesi-Oliveira K, Muotri AR. PMID: 21061307.
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    101. Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. J Neurol Res. 2011; 1(5). Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad GG. PMID: 24348887.
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    102. L1 retrotransposition in neurons is modulated by MeCP2. Nature. 2010 Nov 18; 468(7322):443-6. Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH. PMID: 21085180.
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    103. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 2010 Nov 12; 143(4):527-39. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. PMID: 21074045.
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    104. Hematopoietic stem cell transplantation protects mice from lethal stroke. Exp Neurol. 2010 Oct; 225(2):284-93. Felfly H, Muotri A, Yao H, Haddad GG. PMID: 20547154.
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    105. Coordination of centrosome homeostasis and DNA repair is intact in MCF-7 and disrupted in MDA-MB 231 breast cancer cells. Cancer Res. 2010 Apr 15; 70(8):3320-8. Acu ID, Liu T, Suino-Powell K, Mooney SM, D'Assoro AB, Rowland N, Muotri AR, Correa RG, Niu Y, Kumar R, Salisbury JL. PMID: 20388771.
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    106. Gene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood. Stem Cell Rev Rep. 2009 Dec; 5(4):387-401. Secco M, Moreira YB, Zucconi E, Vieira NM, Jazedje T, Muotri AR, Okamoto OK, Verjovski-Almeida S, Zatz M. PMID: 20058202.
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    107. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus. 2009 Oct; 19(10):1002-7. Muotri AR, Zhao C, Marchetto MC, Gage FH. PMID: 19771587.
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    108. Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One. 2009 Sep 18; 4(9):e7076. Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. PMID: 19763270.
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    109. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat Neurosci. 2009 Sep; 12(9):1097-105. Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH. PMID: 19701198.
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    110. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 2008 Dec 04; 3(6):649-57. Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH. PMID: 19041781.
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    111. Modeling epilepsy with pluripotent human cells. Epilepsy Behav. 2009 Jan; 14 Suppl 1:81-5. Muotri AR. PMID: 18845273.
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    112. Identification of XP complementation groups by recombinant adenovirus carrying DNA repair genes. J Invest Dermatol. 2009 Feb; 129(2):502-6. Leite RA, Marchetto MC, Muotri AR, Vasconcelos Dde M, de Oliveira ZN, Machado MC, Menck CF. PMID: 18685619.
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    113. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Hum Mol Genet. 2008 Apr 15; 17(R1):R67-75. Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. PMID: 18632700.
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    114. Mesenchymal stem cells from umbilical cord: do not discard the cord! Neuromuscul Disord. 2008 Jan; 18(1):17-8. Secco M, Zucconi E, Vieira NM, Fogaça LL, Cerqueira A, Carvalho MD, Jazedje T, Okamoto OK, Muotri AR, Zatz M. PMID: 18155523.
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    115. Identification of small molecules from human embryonic stem cells using metabolomics. Stem Cells Dev. 2007 Dec; 16(6):869-82. Cezar GG, Quam JA, Smith AM, Rosa GJ, Piekarczyk MS, Brown JF, Gage FH, Muotri AR. PMID: 18042039.
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    116. Exploring DNA damage responses in human cells with recombinant adenoviral vectors. Hum Exp Toxicol. 2007 Nov; 26(11):899-906. Armelini MG, Lima-Bessa KM, Marchetto MC, Muotri AR, Chiganças V, Leite RA, Carvalho H, Menck CF. PMID: 18042584.
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    117. The necessary junk: new functions for transposable elements. Hum Mol Genet. 2007 Oct 15; 16 Spec No. 2:R159-67. Muotri AR, Marchetto MC, Coufal NG, Gage FH. PMID: 17911158.
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    118. Multipotent stem cells from umbilical cord: cord is richer than blood! Stem Cells. 2008 Jan; 26(1):146-50. Secco M, Zucconi E, Vieira NM, Fogaça LL, Cerqueira A, Carvalho MD, Jazedje T, Okamoto OK, Muotri AR, Zatz M. PMID: 17932423.
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    119. Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput Biol. 2007 Oct; 3(10):1951-67. Yeo GW, Xu X, Liang TY, Muotri AR, Carson CT, Coufal NG, Gage FH. PMID: 17967047.
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    120. LINE-1 retrotransposition in human embryonic stem cells. Hum Mol Genet. 2007 Jul 01; 16(13):1569-77. Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. PMID: 17468180.
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    121. Generation of neuronal variability and complexity. Nature. 2006 Jun 29; 441(7097):1087-93. Muotri AR, Gage FH. PMID: 16810244.
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    122. Functional lentiviral vectors for xeroderma pigmentosum gene therapy. J Biotechnol. 2006 Dec 01; 126(4):424-30. Marchetto MC, Correa RG, Menck CF, Muotri AR. PMID: 16857285.
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    123. UV-mediated NF-kappaB activation is abolished in deficient XPC/D primary fibroblasts. . 2006 May; 5(10):1085-9. Muotri AR, Bottero V, Tergaonkar V, Correa RG. PMID: 16721051.
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    124. Skeletal muscle cells expressing VEGF induce capillary formation and reduce cardiac injury in rats. Int J Cardiol. 2006 Nov 18; 113(3):348-54. Becker C, Lacchini S, Muotri AR, da Silva GJ, Castelli JB, Vassallo PF, Menck CF, Krieger JE. PMID: 16675047.
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    125. Unconventional translation of mammalian LINE-1 retrotransposons. Genes Dev. 2006 Jan 15; 20(2):210-24. Alisch RS, Garcia-Perez JL, Muotri AR, Gage FH, Moran JV. PMID: 16418485.
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    126. Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci. 2006; 29:77-103. Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. PMID: 16776580.
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    127. Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18644-8. Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH. PMID: 16352714.
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    128. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature. 2005 Jun 16; 435(7044):903-10. Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. PMID: 15959507.
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    129. DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proc Natl Acad Sci U S A. 2005 Apr 19; 102(16):5844-9. Lilley CE, Carson CT, Muotri AR, Gage FH, Weitzman MD. PMID: 15824307.
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    130. Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus. Cancer Gene Ther. 2005 Apr; 12(4):389-96. Armelini MG, Muotri AR, Marchetto MC, de Lima-Bessa KM, Sarasin A, Menck CF. PMID: 15650764.
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    131. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med. 2005 Feb; 11(2):228-32. Martin MJ, Muotri A, Gage F, Varki A. PMID: 15685172.
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    132. Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17759-64. Marchetto MC, Muotri AR, Burns DK, Friedberg EC, Menck CF. PMID: 15598745.
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    133. Vibrating in the background. Nat Genet. 2003 Nov; 35(3):205-7. Muotri AR, Gage FH. PMID: 14593403.
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    134. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6777-82. Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. PMID: 12748381.
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    135. Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer. Hum Gene Ther. 2002 Oct 10; 13(15):1833-44. Muotri AR, Marchetto MC, Zerbini LF, Libermann TA, Ventura AM, Sarasin A, Menck CF. PMID: 12396616.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    136. Low amounts of the DNA repair XPA protein are sufficient to recover UV-resistance. Carcinogenesis. 2002 Jun; 23(6):1039-46. Muotri AR, Marchetto MC, Suzuki MF, Okazaki K, Lotfi CF, Brumatti G, Amarante-Mendes GP, Menck CF. PMID: 12082027.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    137. An adenovirus vector containing the suicide gene thymidine kinase for a broad application in cancer gene therapy. Mem Inst Oswaldo Cruz. 2002 Jun; 97(4):547-52. Magalhaes GS, Muotri AR, Marchetto MC, Menck CF, Ventura AM. PMID: 12118289.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    138. DNA repair and sequence context affect (1)O(2)-induced mutagenesis in bacteria. Nucleic Acids Res. 2001 Jul 01; 29(13):2899-903. Agnez-Lima LF, Napolitano RL, Fuchs RP, Mascio PD, Muotri AR, Menck CF. PMID: 11433036.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    139. Photorepair prevents ultraviolet-induced apoptosis in human cells expressing the marsupial photolyase gene. Cancer Res. 2000 May 01; 60(9):2458-63. Chiganças V, Miyaji EN, Muotri AR, de Fátima Jacysyn J, Amarante-Mendes GP, Yasui A, Menck CF. PMID: 10811124.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    140. Ribozymes and the anti-gene therapy: how a catalytic RNA can be used to inhibit gene function. Gene. 1999 Sep 17; 237(2):303-10. Muotri AR, da Veiga Pereira L, dos Reis Vasques L, Menck CF. PMID: 10521654.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
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