 Christian Nickl
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| Title(s) | , Cellular and Molecular Medicine |
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| School | Health Sciences |
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| vCard | Download vCard |
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 Bibliographic
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Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K. Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia. Cancer Sci. 2019 Jun; 110(6):1931-1946. PMID: 30974024.
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Kang H, Sharma ND, Nickl CK, Devidas M, Loh ML, Hunger SP, Dunsmore KP, Winter SS, Matlawska-Wasowska K. Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL. Biomark Res. 2018; 6:27. PMID: 30159143.
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Perez DR, Nickl CK, Waller A, Delgado-Martin C, Woods T, Sharma ND, Hermiston ML, Loh ML, Hunger SP, Winter SS, Chigaev A, Edwards B, Sklar LA, Matlawska-Wasowska K. High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL. SLAS Discov. 2018 Aug; 23(7):732-741. PMID: 29746793.
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Mayfield JR, Czuchlewski DR, Gale JM, Matlawska-Wasowska K, Vasef MA, Nickl C, Pickett G, Ness SA, Winter SS. Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 05; 64(5). PMID: 27860260.
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Matlawska-Wasowska K, Gale JM, Nickl CK, Khalili P, Shirley B, Wilson BS, Vasef MA, Winter SS. Pyrosequencing for classification of human Fc?RIIIA allotypes: a comparison with PCR-based techniques. Mol Diagn Ther. 2014 Dec; 18(6):665-73. PMID: 25230857.
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Caldwell GB, Howe AK, Nickl CK, Dostmann WR, Ballif BA, Deming PB. Direct modulation of the protein kinase A catalytic subunit a by growth factor receptor tyrosine kinases. J Cell Biochem. 2012 Jan; 113(1):39-48. PMID: 21866565.
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Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure. 2011 Sep 07; 19(9):1317-27. PMID: 21893290; PMCID: PMC3168983.
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Lavogina D, Nickl CK, Enkvist E, Raidaru G, Lust M, Vaasa A, Uri A, Dostmann WR. Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha). Biochim Biophys Acta. 2010 Sep; 1804(9):1857-68. PMID: 20406699.
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Nickl CK, Raidas SK, Zhao H, Sausbier M, Ruth P, Tegge W, Brayden JE, Dostmann WR. (D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha. Biochim Biophys Acta. 2010 Mar; 1804(3):524-32. PMID: 20018259.
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Taylor MS, Okwuchukwuasanya C, Nickl CK, Tegge W, Brayden JE, Dostmann WR. Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation. Mol Pharmacol. 2004 May; 65(5):1111-9. PMID: 15102939.
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Dostmann WR, Tegge W, Frank R, Nickl CK, Taylor MS, Brayden JE. Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Ialpha. Pharmacol Ther. 2002 Feb-Mar; 93(2-3):203-15. PMID: 12191612.
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