Christian Nickl

Title(s)	Staff Res Assoc, Cellular and Molecular Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
vCard	Download vCard

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression. Immunity. 2025 Apr 08; 58(4):826-842.e8. Cobo I, Murillo-Saich J, Alishala M, Calderon S, Coras R, Hemming B, Inkum F, Rosas F, Takei R, Spann N, Prohaska TA, Alabarse PVG, Jeong SJ, Nickl CK, Cheng A, Li B, Vogel A, Weichhart T, Fuster JJ, Le T, Bradstreet TR, Webber AM, Edelson BT, Razani B, Ebert BL, Taneja R, Terkeltaub R, Bryan RL, Guma M, Glass CK. PMID: 40118070.

View in: PubMed Mentions: Fields:
All Allergy and Immunology
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes. Nat Immunol. 2023 Nov; 24(11):1825-1838. Bennett H, Troutman TD, Zhou E, Spann NJ, Link VM, Seidman JS, Nickl CK, Abe Y, Sakai M, Pasillas MP, Marlman JM, Guzman C, Hosseini M, Schnabl B, Glass CK. PMID: 37735593; PMCID: PMC10602851.

View in: PubMed Mentions: 5 Fields:
All Allergy and Immunology
Translation:Animals Cells
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia. J Clin Invest. 2021 03 15; 131(6). Matthijssens F, Sharma ND, Nysus M, Nickl CK, Kang H, Perez DR, Lintermans B, Van Loocke W, Roels J, Peirs S, Demoen L, Pieters T, Reunes L, Lammens T, De Moerloose B, Van Nieuwerburgh F, Deforce DL, Cheung LC, Kotecha RS, Risseeuw MD, Van Calenbergh S, Takarada T, Yoneda Y, van Delft FW, Lock RB, Merkley SD, Chigaev A, Sklar LA, Mullighan CG, Loh ML, Winter SS, Hunger SP, Goossens S, Castillo EF, Ornatowski W, Van Vlierberghe P, Matlawska-Wasowska K. PMID: 33555272; PMCID: PMC7954605.

View in: PubMed Mentions: 18 Fields:
Med Medicine (General)
Translation:Humans Animals Cells
Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139. Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856; PMCID: PMC7028213.

View in: PubMed Mentions: 322 Fields:
Sci Science
Translation:Humans Cells
Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia. Cancer Sci. 2019 Jun; 110(6):1931-1946. Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K. PMID: 30974024; PMCID: PMC6549933.

View in: PubMed Mentions: 18 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL. Biomark Res. 2018; 6:27. Kang H, Sharma ND, Nickl CK, Devidas M, Loh ML, Hunger SP, Dunsmore KP, Winter SS, Matlawska-Wasowska K. PMID: 30159143; PMCID: PMC6107954.

View in: PubMed Mentions: 6
High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL. SLAS Discov. 2018 08; 23(7):732-741. Perez DR, Nickl CK, Waller A, Delgado-Martin C, Woods T, Sharma ND, Hermiston ML, Loh ML, Hunger SP, Winter SS, Chigaev A, Edwards B, Sklar LA, Matlawska-Wasowska K. PMID: 29746793; PMCID: PMC6292518.

View in: PubMed Mentions: 2 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 05; 64(5). Mayfield JR, Czuchlewski DR, Gale JM, Matlawska-Wasowska K, Vasef MA, Nickl C, Pickett G, Ness SA, Winter SS. PMID: 27860260; PMCID: PMC5366086.

View in: PubMed Mentions: 12 Fields:
Hem Hematology Neo Neoplasms Ped Pediatrics
Translation:Humans
Pyrosequencing for classification of human FcγRIIIA allotypes: a comparison with PCR-based techniques. Mol Diagn Ther. 2014 Dec; 18(6):665-73. Matlawska-Wasowska K, Gale JM, Nickl CK, Khalili P, Shirley B, Wilson BS, Vasef MA, Winter SS. PMID: 25230857.

View in: PubMed Mentions: 2 Fields:
Cli Clinical Laboratory Techniques Mol Molecular Biology Pha Pharmacology
Translation:Humans
Direct modulation of the protein kinase A catalytic subunit α by growth factor receptor tyrosine kinases. J Cell Biochem. 2012 Jan; 113(1):39-48. Caldwell GB, Howe AK, Nickl CK, Dostmann WR, Ballif BA, Deming PB. PMID: 21866565; PMCID: PMC3245341.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Cel Cell Biology
Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure. 2011 Sep 07; 19(9):1317-27. Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. PMID: 21893290; PMCID: PMC3168983.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha). Biochim Biophys Acta. 2010 Sep; 1804(9):1857-68. Lavogina D, Nickl CK, Enkvist E, Raidaru G, Lust M, Vaasa A, Uri A, Dostmann WR. PMID: 20406699; PMCID: PMC3071016.

View in: PubMed Mentions: Fields:
Bio Biochemistry Bio Biophysics
(D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha. Biochim Biophys Acta. 2010 Mar; 1804(3):524-32. Nickl CK, Raidas SK, Zhao H, Sausbier M, Ruth P, Tegge W, Brayden JE, Dostmann WR. PMID: 20018259; PMCID: PMC2822062.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Bio Biophysics
Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation. Mol Pharmacol. 2004 May; 65(5):1111-9. Taylor MS, Okwuchukwuasanya C, Nickl CK, Tegge W, Brayden JE, Dostmann WR. PMID: 15102939.

View in: PubMed Mentions: 15 Fields:
Mol Molecular Biology Pha Pharmacology
Translation:Animals
Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Ialpha. Pharmacol Ther. 2002 Feb-Mar; 93(2-3):203-15. Dostmann WR, Tegge W, Frank R, Nickl CK, Taylor MS, Brayden JE. PMID: 12191612.

View in: PubMed Mentions: 8 Fields:
Dru Drug Therapy Pha Pharmacology The Therapeutics
Translation:Humans Animals Cells