 Christian Nickl
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| Title(s) | , Cellular and Molecular Medicine |
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| School | Health Sciences |
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| vCard | Download vCard |
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 Bibliographic
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Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139. PMID: 31727856.
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Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K. Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia. Cancer Sci. 2019 Jun; 110(6):1931-1946. PMID: 30974024.
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Kang H, Sharma ND, Nickl CK, Devidas M, Loh ML, Hunger SP, Dunsmore KP, Winter SS, Matlawska-Wasowska K. Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL. Biomark Res. 2018; 6:27. PMID: 30159143.
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Perez DR, Nickl CK, Waller A, Delgado-Martin C, Woods T, Sharma ND, Hermiston ML, Loh ML, Hunger SP, Winter SS, Chigaev A, Edwards B, Sklar LA, Matlawska-Wasowska K. High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL. SLAS Discov. 2018 08; 23(7):732-741. PMID: 29746793.
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Mayfield JR, Czuchlewski DR, Gale JM, Matlawska-Wasowska K, Vasef MA, Nickl C, Pickett G, Ness SA, Winter SS. Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 05; 64(5). PMID: 27860260.
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Matlawska-Wasowska K, Gale JM, Nickl CK, Khalili P, Shirley B, Wilson BS, Vasef MA, Winter SS. Pyrosequencing for classification of human Fc?RIIIA allotypes: a comparison with PCR-based techniques. Mol Diagn Ther. 2014 Dec; 18(6):665-73. PMID: 25230857.
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Caldwell GB, Howe AK, Nickl CK, Dostmann WR, Ballif BA, Deming PB. Direct modulation of the protein kinase A catalytic subunit a by growth factor receptor tyrosine kinases. J Cell Biochem. 2012 Jan; 113(1):39-48. PMID: 21866565.
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Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure. 2011 Sep 07; 19(9):1317-27. PMID: 21893290.
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Lavogina D, Nickl CK, Enkvist E, Raidaru G, Lust M, Vaasa A, Uri A, Dostmann WR. Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha). Biochim Biophys Acta. 2010 Sep; 1804(9):1857-68. PMID: 20406699.
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Nickl CK, Raidas SK, Zhao H, Sausbier M, Ruth P, Tegge W, Brayden JE, Dostmann WR. (D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha. Biochim Biophys Acta. 2010 Mar; 1804(3):524-32. PMID: 20018259.
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Taylor MS, Okwuchukwuasanya C, Nickl CK, Tegge W, Brayden JE, Dostmann WR. Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation. Mol Pharmacol. 2004 May; 65(5):1111-9. PMID: 15102939.
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Dostmann WR, Tegge W, Frank R, Nickl CK, Taylor MS, Brayden JE. Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Ialpha. Pharmacol Ther. 2002 Feb-Mar; 93(2-3):203-15. PMID: 12191612.
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