Don Cleveland

Title(s)Professor, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 
    Collapse Overview
    Cleveland is interested in the genes and proteins involved in mitotic spindle assembly and faithful chromosome segregation just prior to division. This process is particularly relevant to the development of cancer because it is thought that cancer cells mis-segregate chromosomes due to errors in mitosis resulting in aneuploidy. The major pathway guarding against whole chromosome mis-segregation is the mitotic checkpoint, a cell cycle control mechanism in which the centromeres of unattached chromosomes generate an inhibitor that blocks cyclin B degradation and advance across mitosis. The antitumor drug taxol is effective by chronically activating this checkpoint. In the past year, starting from all purified components Cleveland’s efforts have reconstructed mitotic checkpoint signaling in vitro. Additionally, abnormalities in number of microtubule organizing centers (centrosomes) can promote errors in spindle formation that lead to subsequent chromosome missegregation and extra centrosomes are associated with many cancers. Like DNA, centrosomes are duplicated only once each cell cycle. The duplication process is governed by polo-like kinase 4 (Plk4). Cleveland’s recent efforts identified how centrosome over-replication is blocked: kinase-mediated, autoregulated instability of Plk4 acts to self-limit Plk4 activity so as to prevent centrosome amplification.

    Clinical Interests
    - Cancer Biology
    - Amyotrophic lateral sclerosis

    Collapse Research 
    Collapse Research Activities and Funding
    In vivo modelling and therapy development for stathmin-2 loss in TDP-43 proteinopathies
    NIH RF1NS124203Aug 1, 2021 - Jul 31, 2024
    Role: Co-Principal Investigator
    TDP-43 acetylation, phase separation, aggregation, and clearance by antibody-mediated degradation
    NIH R01NS121604Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Determining stathmin-2 function and potential as a therapeutic target in ALS/FTD
    NIH R01NS112503Apr 1, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis
    NIH R35GM122476May 1, 2017 - Feb 28, 2022
    Role: Principal Investigator
    Junior Faculty and Postdoctoral Fellows Career Development Workshop
    NIH R13GM111037Sep 15, 2014 - Aug 31, 2016
    Role: Principal Investigator
    ALS therapies and genomics for mutant TDP-43 and TLS/FUS
    NIH RC1NS069144Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Delivery of therapeutic genes in motor neuron disease
    NIH RC2NS069476Sep 30, 2009 - Aug 31, 2012
    Role: Co-Principal Investigator
    Mammalian Centromere Assembly
    NIH R01GM074150Feb 1, 2006 - Aug 31, 2018
    Role: Principal Investigator
    6TH INTERNATIONAL CONGRESS ON CELL BIOLOGY
    NIH R13CA072388Sep 30, 1996 - Sep 29, 1997
    Role: Principal Investigator
    Disease mechanism in ALS and frontotemporal dementia
    NIH R01NS027036Apr 1, 1989 - Aug 31, 2022
    Role: Principal Investigator
    Neurofilaments, SOD1 and Motor Neuron Diseases
    NIH R37NS027036Apr 1, 1989 - May 31, 2012
    Role: Principal Investigator
    MICROTUBULE REGULATION: CONTROL OF EXPRESSION OF TUBULI
    NIH K04HD000504Sep 30, 1982 - Aug 31, 1987
    Role: Principal Investigator
    Guarding the Genome: Aneuploidy and tumorigenesis
    NIH R01GM029513Jul 1, 1981 - Aug 31, 2017
    Role: Principal Investigator
    MICROTUBULE REGULATION
    NIH R37GM029513Jul 1, 1981 - Jun 30, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS. Mol Neurodegener. 2024 Jun 11; 19(1):46. Vazquez-Sanchez S, Tilkin B, Gasset-Rosa F, Zhang S, Piol D, McAlonis-Downes M, Artates J, Govea-Perez N, Verresen Y, Guo L, Cleveland DW, Shorter J, Da Cruz S. PMID: 38862967; PMCID: PMC11165889.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS. bioRxiv. 2024 Jun 03. Vazquez-Sanchez S, Tilkin B, Gasset-Rosa F, Zhang S, Piol D, McAlonis-Downes M, Artates J, Govea-Perez N, Verresen Y, Guo L, Cleveland DW, Shorter J, Da Cruz S. PMID: 38895337; PMCID: PMC11185515.
      View in: PubMed   Mentions:
    3. A phage nucleus-associated RNA-binding protein is required for jumbo phage infection. Nucleic Acids Res. 2024 May 08; 52(8):4440-4455. Enustun E, Armbruster EG, Lee J, Zhang S, Yee BA, Malukhina K, Gu Y, Deep A, Naritomi JT, Liang Q, Aigner S, Adler BA, Cress BF, Doudna JA, Chaikeeratisak V, Cleveland DW, Ghassemian M, Bintu B, Yeo GW, Pogliano J, Corbett KD. PMID: 38554115; PMCID: PMC11077065.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    4. CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation. Neurobiol Dis. 2024 Jun 15; 196:106516. Ko VI, Ong K, Cleveland DW, Yu H, Ravits JM. PMID: 38677657.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease. Acta Neuropathol. 2024 01 04; 147(1):9. Agra Almeida Quadros AR, Li Z, Wang X, Ndayambaje IS, Aryal S, Ramesh N, Nolan M, Jayakumar R, Han Y, Stillman H, Aguilar C, Wheeler HJ, Connors T, Lopez-Erauskin J, Baughn MW, Melamed Z, Beccari MS, Olmedo Martínez L, Canori M, Lee CZ, Moran L, Draper I, Kopin AS, Oakley DH, Dickson DW, Cleveland DW, Hyman BT, Das S, Ertekin-Taner N, Lagier-Tourenne C. PMID: 38175301; PMCID: PMC10766724.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation. Nat Neurosci. 2024 Jan; 27(1):34-47. López-Erauskin J, Bravo-Hernandez M, Presa M, Baughn MW, Melamed Z, Beccari MS, Agra de Almeida Quadros AR, Arnold-Garcia O, Zuberi A, Ling K, Platoshyn O, Niño-Jara E, Ndayambaje IS, McAlonis-Downes M, Cabrera L, Artates JW, Ryan J, Hermann A, Ravits J, Bennett CF, Jafar-Nejad P, Rigo F, Marsala M, Lutz CM, Cleveland DW, Lagier-Tourenne C. PMID: 37996528; PMCID: PMC10842032.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    7. Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates. J Med Chem. 2023 11 23; 66(22):15084-15093. Gao P, Zhang Q, Keely D, Cleveland DW, Ye Y, Zheng W, Shen M, Yu H. PMID: 37937963; PMCID: PMC10810226.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Scrambling the genome in cancer: causes and consequences of complex chromosome rearrangements. Nat Rev Genet. 2024 Mar; 25(3):196-210. Krupina K, Goginashvili A, Cleveland DW. PMID: 37938738; PMCID: PMC10922386.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification. bioRxiv. 2023 Nov 02. Nguyen TB, Miramontes R, Chillon-Marinas C, Maimon R, Vazquez-Sanchez S, Lau AL, McClure NR, England WE, Singha M, Stocksdale JT, Jang KH, Jung S, McKnight JI, Ho LN, Faull RLM, Steffan JS, Reidling JC, Jang C, Lee G, Cleveland DW, Lagier-Tourenne C, Spitale RC, Thompson LM. PMID: 37961595; PMCID: PMC10635028.
      View in: PubMed   Mentions: 1  
    10. A phage nucleus-associated RNA-binding protein is required for jumbo phage infection. bioRxiv. 2023 Sep 22. Enustun E, Armbruster EG, Lee J, Zhang S, Yee BA, Gu Y, Deep A, Naritomi JT, Liang Q, Aigner S, Adler BA, Cress BF, Doudna JA, Chaikeeratisak V, Cleveland DW, Ghassemian M, Yeo GW, Pogliano J, Corbett KD. PMID: 37790334; PMCID: PMC10542519.
      View in: PubMed   Mentions:
    11. Mitotic tethering enables inheritance of shattered micronuclear chromosomes. Nature. 2023 Jun; 618(7967):1049-1056. Trivedi P, Steele CD, Au FKC, Alexandrov LB, Cleveland DW. PMID: 37316668; PMCID: PMC10424572.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    12. Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats. Nature. 2023 04; 616(7957):504-509. Li JSZ, Abbasi A, Kim DH, Lippman SM, Alexandrov LB, Cleveland DW. PMID: 37046091; PMCID: PMC10328181.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    13. GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells. Mol Ther Nucleic Acids. 2023 Jun 13; 32:289-301. McMahon MA, Rahdar M, Mukhopadhyay S, Bui HH, Hart C, Damle S, Courtney M, Baughn MW, Cleveland DW, Bennett CF. PMID: 37096163; PMCID: PMC10122063.
      View in: PubMed   Mentions: 1  
    14. Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies. Science. 2023 03 17; 379(6637):1140-1149. Baughn MW, Melamed Z, López-Erauskin J, Beccari MS, Ling K, Zuberi A, Presa M, Gonzalo-Gil E, Maimon R, Vazquez-Sanchez S, Chaturvedi S, Bravo-Hernández M, Taupin V, Moore S, Artates JW, Acks E, Ndayambaje IS, Agra de Almeida Quadros AR, Jafar-Nejad P, Rigo F, Bennett CF, Lutz C, Lagier-Tourenne C, Cleveland DW. PMID: 36927019; PMCID: PMC10148063.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    15. A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell. 2022 12 01; 29(12):1685-1702.e22. Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz SW, Priebe T, Öttl M, Dong J, Meijer M, Janssen LJM, Lourenco VS, van der Kant R, Crusius D, Paquet D, Raulin AC, Bu G, Held A, Wainger BJ, Gabriele RMC, Casey JM, Wray S, Abu-Bonsrah D, Parish CL, Beccari MS, Cleveland DW, Li E, Rose IVL, Kampmann M, Calatayud Aristoy C, Verstreken P, Heinrich L, Chen MY, Schüle B, Dou D, Holzbaur ELF, Zanellati MC, Basundra R, Deshmukh M, Cohen S, Khanna R, Raman M, Nevin ZS, Matia M, Van Lent J, Timmerman V, Conklin BR, Johnson Chase K, Zhang K, Funes S, Bosco DA, Erlebach L, Welzer M, Kronenberg-Versteeg D, Lyu G, Arenas E, Coccia E, Sarrafha L, Ahfeldt T, Marioni JC, Skarnes WC, Cookson MR, Ward ME, Merkle FT. PMID: 36459969; PMCID: PMC9782786.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    16. Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease. Proc Natl Acad Sci U S A. 2022 12 06; 119(49):e2123487119. Jambeau M, Meyer KD, Hruska-Plochan M, Tabet R, Lee CZ, Ray-Soni A, Aguilar C, Savage K, Mishra N, Cavegn N, Borter P, Lin CC, Jansen-West KR, Jiang J, Freyermuth F, Li N, De Rossi P, Pérez-Berlanga M, Jiang X, Daughrity LM, Pereira J, Narayanan S, Gu Y, Dhokai S, Dalkilic-Liddle I, Maniecka Z, Weber J, Workman M, McAlonis-Downes M, Berezovski E, Zhang YJ, Berry J, Wainger BJ, Kankel MW, Rushe M, Hock C, Nitsch RM, Cleveland DW, Petrucelli L, Gendron TF, Montrasio F, Grimm J, Polymenidou M, Lagier-Tourenne C. PMID: 36454749; PMCID: PMC9894253.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    17. Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition. Nat Cell Biol. 2022 09; 24(9):1378-1393. Lu S, Hu J, Arogundade OA, Goginashvili A, Vazquez-Sanchez S, Diedrich JK, Gu J, Blum J, Oung S, Ye Q, Yu H, Ravits J, Liu C, Yates JR, Cleveland DW. PMID: 36075972; PMCID: PMC9872726.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    18. Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathol. 2021 12; 142(6):985-1001. Diaz-Garcia S, Ko VI, Vazquez-Sanchez S, Chia R, Arogundade OA, Rodriguez MJ, Traynor BJ, Cleveland D, Ravits J. PMID: 34618203; PMCID: PMC8568872.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    19. Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation. Mol Neurodegener. 2021 09 06; 16(1):61. Sanjuan-Ruiz I, Govea-Perez N, McAlonis-Downes M, Dieterle S, Megat S, Dirrig-Grosch S, Picchiarelli G, Piol D, Zhu Q, Myers B, Lee CZ, Cleveland DW, Lagier-Tourenne C, Da Cruz S, Dupuis L. PMID: 34488813; PMCID: PMC8419956.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    20. Transient genomic instability drives tumorigenesis through accelerated clonal evolution. Genes Dev. 2021 08 01; 35(15-16):1093-1108. Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, Fisch K, Foijer F, Cleveland DW. PMID: 34266887; PMCID: PMC8336898.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    21. Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB. Nat Neurosci. 2021 08; 24(8):1089-1099. Maimon R, Chillon-Marinas C, Snethlage CE, Singhal SM, McAlonis-Downes M, Ling K, Rigo F, Bennett CF, Da Cruz S, Hnasko TS, Muotri AR, Cleveland DW. PMID: 34083786; PMCID: PMC8338913.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    22. Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss. Proc Natl Acad Sci U S A. 2021 05 11; 118(19). William WN, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. PMID: 33952700; PMCID: PMC8126856.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    23. Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype. Front Aging Neurosci. 2021; 13:658226. Theunissen F, Anderton RS, Mastaglia FL, Flynn LL, Winter SJ, James I, Bedlack R, Hodgetts S, Fletcher S, Wilton SD, Laing NG, MacShane M, Needham M, Saunders A, Mackay-Sim A, Melamed Z, Ravits J, Cleveland DW, Akkari PA. PMID: 33841129; PMCID: PMC8033025.
      View in: PubMed   Mentions: 24  
    24. Publisher Correction: Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021 Mar; 591(7850):E19. Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. PMID: 33649505.
      View in: PubMed   Mentions: 4     Fields:    
    25. Causes and consequences of micronuclei. Curr Opin Cell Biol. 2021 06; 70:91-99. Krupina K, Goginashvili A, Cleveland DW. PMID: 33610905; PMCID: PMC8119331.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    26. The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nat Commun. 2021 01 21; 12(1):502. Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR, Villa E, Cleveland DW, Corbett KD. PMID: 33479198; PMCID: PMC7820290.
      View in: PubMed   Mentions: 229     Fields:    Translation:HumansCells
    27. Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021 03; 591(7848):137-141. Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. PMID: 33361815; PMCID: PMC7933129.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansCells
    28. HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science. 2021 02 05; 371(6529). Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, Toprani D, Beccari MS, Yates JR, Da Cruz S, Newby JM, Lafarga M, Gladfelter AS, Villa E, Cleveland DW. PMID: 33335017; PMCID: PMC8286096.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    29. Antisense Drugs Make Sense for Neurological Diseases. Annu Rev Pharmacol Toxicol. 2021 01 06; 61:831-852. Bennett CF, Kordasiewicz HB, Cleveland DW. PMID: 33035446; PMCID: PMC8682074.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    30. Author Correction: Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature. 2020 Aug; 584(7820):E17. Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD. PMID: 32724206.
      View in: PubMed   Mentions: 3     Fields:    
    31. The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. bioRxiv. 2020 Jul 31. Lu S, Ye Q, Singh D, Villa E, Cleveland DW, Corbett KD. PMID: 32766587; PMCID: PMC7402048.
      View in: PubMed   Mentions:
    32. Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature. 2020 06; 582(7813):550-556. Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD. PMID: 32581380; PMCID: PMC7521455.
      View in: PubMed   Mentions: 211     Fields:    Translation:HumansAnimalsCells
    33. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2020 04 22; 106(2):354. López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S. PMID: 32325059; PMCID: PMC7184958.
      View in: PubMed   Mentions: 5     Fields:    
    34. Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72. Nat Neurosci. 2020 05; 23(5):615-624. Zhu Q, Jiang J, Gendron TF, McAlonis-Downes M, Jiang L, Taylor A, Diaz Garcia S, Ghosh Dastidar S, Rodriguez MJ, King P, Zhang Y, La Spada AR, Xu H, Petrucelli L, Ravits J, Da Cruz S, Lagier-Tourenne C, Cleveland DW. PMID: 32284607; PMCID: PMC7384305.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    35. Gene expression regulated by RNA stability. Science. 2020 01 03; 367(6473):29. Shoshani O, Cleveland DW. PMID: 31896707.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    36. Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS. Nat Med. 2020 01; 26(1):118-130. Bravo-Hernandez M, Tadokoro T, Navarro MR, Platoshyn O, Kobayashi Y, Marsala S, Miyanohara A, Juhas S, Juhasova J, Skalnikova H, Tomori Z, Vanicky I, Studenovska H, Proks V, Chen P, Govea-Perez N, Ditsworth D, Ciacci JD, Gao S, Zhu W, Ahrens ET, Driscoll SP, Glenn TD, McAlonis-Downes M, Da Cruz S, Pfaff SL, Kaspar BK, Cleveland DW, Marsala M. PMID: 31873312; PMCID: PMC8171115.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    37. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. 2019 12 04; 104(5):885-898.e8. Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, Cleveland DW, Qiu Z, Rothstein JD, Shorter J, Gao FB, Bassik MC, Sun S. PMID: 31587919; PMCID: PMC6895427.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    38. Antisense Oligonucleotide Therapies for Neurodegenerative Diseases. Annu Rev Neurosci. 2019 07 08; 42:385-406. Bennett CF, Krainer AR, Cleveland DW. PMID: 31283897; PMCID: PMC7427431.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimals
    39. BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res. 2019 07; 29(7):562-578. Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R, Yao X. PMID: 31201382; PMCID: PMC6796941.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    40. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nat Cell Biol. 2019 06; 21(6):743-754. Nechemia-Arbely Y, Miga KH, Shoshani O, Aslanian A, McMahon MA, Lee AY, Fachinetti D, Yates JR, Ren B, Cleveland DW. PMID: 31160708; PMCID: PMC7015266.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    41. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. J Clin Invest. 2019 05 21; 129(8):3103-3120. Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Zhang D, Huang TY, Xu H. PMID: 31112137; PMCID: PMC6668683.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    42. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019 04 17; 102(2):339-357.e7. Gasset-Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, Shorter J, Da Cruz S, Cleveland DW. PMID: 30853299; PMCID: PMC6548321.
      View in: PubMed   Mentions: 210     Fields:    Translation:HumansAnimalsCells
    43. Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements. Nat Genet. 2019 04; 51(4):705-715. Ly P, Brunner SF, Shoshani O, Kim DH, Lan W, Pyntikova T, Flanagan AM, Behjati S, Page DC, Campbell PJ, Cleveland DW. PMID: 30833795; PMCID: PMC6441390.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    44. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. Elife. 2019 02 12; 8. Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW. PMID: 30747709; PMCID: PMC6389288.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    45. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci. 2019 02; 22(2):180-190. Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, Rigo F, Da Cruz S, Ravits J, Lagier-Tourenne C, Cleveland DW. PMID: 30643298; PMCID: PMC6348009.
      View in: PubMed   Mentions: 228     Fields:    Translation:HumansCells
    46. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nat Commun. 2019 01 11; 10(1):175. Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. PMID: 30635586; PMCID: PMC6329807.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    47. TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC. Nat Commun. 2018 10 19; 9(1):4354. Kim DH, Han JS, Ly P, Ye Q, McMahon MA, Myung K, Corbett KD, Cleveland DW. PMID: 30341343; PMCID: PMC6195577.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    48. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018 11 21; 100(4):816-830.e7. López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S. PMID: 30344044; PMCID: PMC6277851.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    49. Tuning Apoptosis and Neuroinflammation: TBK1 Restrains RIPK1. Cell. 2018 09 06; 174(6):1339-1341. Yu H, Cleveland DW. PMID: 30193106.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    50. Probing Mitotic CENP-E Kinesin with the Tethered Cargo Motion Assay and Laser Tweezers. Biophys J. 2018 06 05; 114(11):2640-2652. Gudimchuk N, Tarasovetc EV, Mustyatsa V, Drobyshev AL, Vitre B, Cleveland DW, Ataullakhanov FI, Grishchuk EL. PMID: 29874614; PMCID: PMC6129181.
      View in: PubMed   Mentions: 10     Fields:    
    51. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. Acta Neuropathol. 2018 09; 136(3):425-443. Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, La Spada AR. PMID: 29725819; PMCID: PMC6098723.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    52. Chemically Modified Cpf1-CRISPR RNAs Mediate Efficient Genome Editing in Mammalian Cells. Mol Ther. 2018 May 02; 26(5):1228-1240. McMahon MA, Prakash TP, Cleveland DW, Bennett CF, Rahdar M. PMID: 29650467; PMCID: PMC5993945.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    53. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. 2018 01 25; 553(7689):467-472. Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. PMID: 29342134; PMCID: PMC5785464.
      View in: PubMed   Mentions: 693     Fields:    Translation:HumansAnimalsCells
    54. C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation. Nat Commun. 2018 01 04; 9(1):51. Cheng W, Wang S, Mestre AA, Fu C, Makarem A, Xian F, Hayes LR, Lopez-Gonzalez R, Drenner K, Jiang J, Cleveland DW, Sun S. PMID: 29302060; PMCID: PMC5754368.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    55. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis. Acta Neuropathol. 2018 03; 135(3):459-474. Saberi S, Stauffer JE, Jiang J, Garcia SD, Taylor AE, Schulte D, Ohkubo T, Schloffman CL, Maldonado M, Baughn M, Rodriguez MJ, Pizzo D, Cleveland D, Ravits J. PMID: 29196813; PMCID: PMC5935138.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    56. Rethinking Unconventional Translation in Neurodegeneration. Cell. 2017 Nov 16; 171(5):994-1000. Gao FB, Richter JD, Cleveland DW. PMID: 29149615; PMCID: PMC5728172.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    57. Biological Spectrum of Amyotrophic Lateral Sclerosis Prions. Cold Spring Harb Perspect Med. 2017 Nov 01; 7(11). Polymenidou M, Cleveland DW. PMID: 28062558; PMCID: PMC5666626.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    58. Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis. Trends Cell Biol. 2017 12; 27(12):917-930. Ly P, Cleveland DW. PMID: 28899600; PMCID: PMC5696049.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    59. The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. EMBO J. 2017 08 15; 36(16):2419-2434. Ye Q, Kim DH, Dereli I, Rosenberg SC, Hagemann G, Herzog F, Tóth A, Cleveland DW, Corbett KD. PMID: 28659378; PMCID: PMC5556265.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    60. Interrogating cell division errors using random and chromosome-specific missegregation approaches. Cell Cycle. 2017 Jul 03; 16(13):1252-1258. Ly P, Cleveland DW. PMID: 28650219; PMCID: PMC5531625.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    61. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nat Commun. 2017 06 09; 8:15775. Guo LY, Allu PK, Zandarashvili L, McKinley KL, Sekulic N, Dawicki-McKenna JM, Fachinetti D, Logsdon GA, Jamiolkowski RM, Cleveland DW, Cheeseman IM, Black BE. PMID: 28598437; PMCID: PMC5472775.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    62. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport. Neuron. 2017 Apr 05; 94(1):48-57.e4. Gasset-Rosa F, Chillon-Marinas C, Goginashvili A, Atwal RS, Artates JW, Tabet R, Wheeler VC, Bang AG, Cleveland DW, Lagier-Tourenne C. PMID: 28384474; PMCID: PMC5479704.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    63. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathol. 2017 06; 133(6):907-922. Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S. PMID: 28357566; PMCID: PMC5427168.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    64. Misfolded SOD1 is not a primary component of sporadic ALS. Acta Neuropathol. 2017 07; 134(1):97-111. Da Cruz S, Bui A, Saberi S, Lee SK, Stauffer J, McAlonis-Downes M, Schulte D, Pizzo DP, Parone PA, Cleveland DW, Ravits J. PMID: 28247063; PMCID: PMC5472502.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    65. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. J Cell Biol. 2017 03 06; 216(3):607-621. Nechemia-Arbely Y, Fachinetti D, Miga KH, Sekulic N, Soni GV, Kim DH, Wong AK, Lee AY, Nguyen K, Dekker C, Ren B, Black BE, Cleveland DW. PMID: 28235947; PMCID: PMC5350519.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    66. Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals. Dev Cell. 2017 02 06; 40(3):313-322.e5. Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ. PMID: 28132847; PMCID: PMC5296221.
      View in: PubMed   Mentions: 178     Fields:    Translation:AnimalsCells
    67. CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres. Dev Cell. 2017 01 09; 40(1):104-113. Fachinetti D, Logsdon GA, Abdullah A, Selzer EB, Cleveland DW, Black BE. PMID: 28073008; PMCID: PMC5235356.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    68. Bidirectional Transcriptional Inhibition as Therapy for ALS/FTD Caused by Repeat Expansion in C9orf72. Neuron. 2016 Dec 21; 92(6):1160-1163. Jiang J, Cleveland DW. PMID: 28009271.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    69. Gene therapy: Gene-editing therapy for neurological disease. Nat Rev Neurol. 2017 01; 13(1):7-9. McMahon MA, Cleveland DW. PMID: 27982043.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    70. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nat Cell Biol. 2017 Jan; 19(1):68-75. Ly P, Teitz LS, Kim DH, Shoshani O, Skaletsky H, Fachinetti D, Page DC, Cleveland DW. PMID: 27918550; PMCID: PMC5539760.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    71. CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly. Cell Rep. 2016 11 22; 17(9):2394-2404. Hoffmann S, Dumont M, Barra V, Ly P, Nechemia-Arbely Y, McMahon MA, Hervé S, Cleveland DW, Fachinetti D. PMID: 27880912; PMCID: PMC5134894.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    72. Decoding ALS: from genes to mechanism. Nature. 2016 Nov 10; 539(7628):197-206. Taylor JP, Brown RH, Cleveland DW. PMID: 27830784; PMCID: PMC5585017.
      View in: PubMed   Mentions: 950     Fields:    Translation:HumansAnimalsCells
    73. Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. Mol Ther Methods Clin Dev. 2016; 3:16046. Miyanohara A, Kamizato K, Juhas S, Juhasova J, Navarro M, Marsala S, Lukacova N, Hruska-Plochan M, Curtis E, Gabel B, Ciacci J, Ahrens ET, Kaspar BK, Cleveland D, Marsala M. PMID: 27462649; PMCID: PMC4943453.
      View in: PubMed   Mentions: 19  
    74. Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radic Biol Med. 2016 08; 97:95-108. Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, Jaquet V. PMID: 27212019.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    75. Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. Neuron. 2016 05 04; 90(3):535-50. Jiang J, Zhu Q, Gendron TF, Saberi S, McAlonis-Downes M, Seelman A, Stauffer JE, Jafar-Nejad P, Drenner K, Schulte D, Chun S, Sun S, Ling SC, Myers B, Engelhardt J, Katz M, Baughn M, Platoshyn O, Marsala M, Watt A, Heyser CJ, Ard MC, De Muynck L, Daughrity LM, Swing DA, Tessarollo L, Jung CJ, Delpoux A, Utzschneider DT, Hedrick SM, de Jong PJ, Edbauer D, Van Damme P, Petrucelli L, Shaw CE, Bennett CF, Da Cruz S, Ravits J, Rigo F, Cleveland DW, Lagier-Tourenne C. PMID: 27112497; PMCID: PMC4860075.
      View in: PubMed   Mentions: 270     Fields:    Translation:AnimalsCells
    76. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nat Neurosci. 2016 05; 19(5):668-677. Zhang YJ, Gendron TF, Grima JC, Sasaguri H, Jansen-West K, Xu YF, Katzman RB, Gass J, Murray ME, Shinohara M, Lin WL, Garrett A, Stankowski JN, Daughrity L, Tong J, Perkerson EA, Yue M, Chew J, Castanedes-Casey M, Kurti A, Wang ZS, Liesinger AM, Baker JD, Jiang J, Lagier-Tourenne C, Edbauer D, Cleveland DW, Rademakers R, Boylan KB, Bu G, Link CD, Dickey CA, Rothstein JD, Dickson DW, Fryer JD, Petrucelli L. PMID: 26998601; PMCID: PMC5138863.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansAnimalsCells
    77. CELL BIOLOGY. Disrupted nuclear import-export in neurodegeneration. Science. 2016 Jan 08; 351(6269):125-6. Da Cruz S, Cleveland DW. PMID: 26744395; PMCID: PMC4842317.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    78. Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism. Cell Metab. 2016 Feb 09; 23(2):280-91. Quaegebeur A, Segura I, Schmieder R, Verdegem D, Decimo I, Bifari F, Dresselaers T, Eelen G, Ghosh D, Davidson SM, Schoors S, Broekaert D, Cruys B, Govaerts K, De Legher C, Bouché A, Schoonjans L, Ramer MS, Hung G, Bossaert G, Cleveland DW, Himmelreich U, Voets T, Lemmens R, Bennett CF, Robberecht W, De Bock K, Dewerchin M, Ghesquière B, Fendt SM, Carmeliet P. PMID: 26774962; PMCID: PMC4880550.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    79. Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):E6993-7002. Sun S, Sun Y, Ling SC, Ferraiuolo L, McAlonis-Downes M, Zou Y, Drenner K, Wang Y, Ditsworth D, Tokunaga S, Kopelevich A, Kaspar BK, Lagier-Tourenne C, Cleveland DW. PMID: 26621731; PMCID: PMC4687558.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    80. Synthetic CRISPR RNA-Cas9-guided genome editing in human cells. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):E7110-7. Rahdar M, McMahon MA, Prakash TP, Swayze EE, Bennett CF, Cleveland DW. PMID: 26589814; PMCID: PMC4697396.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    81. Epidermal development, growth control, and homeostasis in the face of centrosome amplification. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):E6311-20. Kulukian A, Holland AJ, Vitre B, Naik S, Cleveland DW, Fuchs E. PMID: 26578791; PMCID: PMC4655514.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    82. Chronic centrosome amplification without tumorigenesis. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):E6321-30. Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. PMID: 26578792; PMCID: PMC4655534.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    83. Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72. Acta Neuropathol. 2015 Dec; 130(6):863-76. van Blitterswijk M, Gendron TF, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Daughrity LM, Murray ME, Heckman MG, Jiang J, Lagier-Tourenne C, Edbauer D, Cleveland DW, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Petrucelli L, Boeve BF, Graff-Radford NR, Boylan KB, Dickson DW, Rademakers R. PMID: 26437865; PMCID: PMC4655160.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    84. Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers. Acta Neuropathol. 2015 Oct; 130(4):559-73. Gendron TF, van Blitterswijk M, Bieniek KF, Daughrity LM, Jiang J, Rush BK, Pedraza O, Lucas JA, Murray ME, Desaro P, Robertson A, Overstreet K, Thomas CS, Crook JE, Castanedes-Casey M, Rousseau L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Graff-Radford NR, Rademakers R, Lagier-Tourenne C, Edbauer D, Cleveland DW, Dickson DW, Petrucelli L, Boylan KB. PMID: 26350237; PMCID: PMC4575385.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    85. MYC Is a Major Determinant of Mitotic Cell Fate. Cancer Cell. 2015 Jul 13; 28(1):129-40. Topham C, Tighe A, Ly P, Bennett A, Sloss O, Nelson L, Ridgway RA, Huels D, Littler S, Schandl C, Sun Y, Bechi B, Procter DJ, Sansom OJ, Cleveland DW, Taylor SS. PMID: 26175417; PMCID: PMC4518499.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    86. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathol Commun. 2015 Jun 25; 3:36. Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE. PMID: 26108367; PMCID: PMC4479086.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    87. DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function. Dev Cell. 2015 May 04; 33(3):314-27. Fachinetti D, Han JS, McMahon MA, Ly P, Abdullah A, Wong AJ, Cleveland DW. PMID: 25942623; PMCID: PMC4421092.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    88. The curious incident of the translational dog that didn't bark. Trends Cell Biol. 2015 Apr; 25(4):187-9. Bertuzzi S, Cleveland DW. PMID: 25817192; PMCID: PMC4508195.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    89. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Mol Biol Cell. 2015 May 15; 26(10):1845-56. Holland AJ, Reis RM, Niessen S, Pereira C, Andres DA, Spielmann HP, Cleveland DW, Desai A, Gassmann R. PMID: 25808490; PMCID: PMC4436830.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    90. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. Neuron. 2015 Apr 08; 86(1):218-32. Israelson A, Ditsworth D, Sun S, Song S, Liang J, Hruska-Plochan M, McAlonis-Downes M, Abu-Hamad S, Zoltsman G, Shani T, Maldonado M, Bui A, Navarro M, Zhou H, Marsala M, Kaspar BK, Da Cruz S, Cleveland DW. PMID: 25801706; PMCID: PMC4393372.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    91. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nat Commun. 2015 Jan 27; 6:6171. Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, Cleveland DW. PMID: 25625564; PMCID: PMC4338613.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    92. Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):E4185-93. Han JS, Vitre B, Fachinetti D, Cleveland DW. PMID: 25246557; PMCID: PMC4210015.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    93. Special Issue on amyotrophic lateral sclerosis. Exp Neurol. 2014 Dec; 262 Pt B:73-4. Traynor BJ, Cleveland DW. PMID: 25158310; PMCID: PMC4559336.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    94. Polo-like kinase 4 inhibition: a strategy for cancer therapy? Cancer Cell. 2014 Aug 11; 26(2):151-3. Holland AJ, Cleveland DW. PMID: 25117704; PMCID: PMC4148003.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    95. The quantitative architecture of centromeric chromatin. Elife. 2014 Jul 15; 3:e02137. Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LE. PMID: 25027692; PMCID: PMC4091408.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    96. Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E. Mol Biol Cell. 2014 Aug 01; 25(15):2272-81. Vitre B, Gudimchuk N, Borda R, Kim Y, Heuser JE, Cleveland DW, Grishchuk EL. PMID: 24920822; PMCID: PMC4116301.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    97. Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism. Hum Genet. 2014 Aug; 133(8):1023-39. Mirzaa GM, Vitre B, Carpenter G, Abramowicz I, Gleeson JG, Paciorkowski AR, Cleveland DW, Dobyns WB, O'Driscoll M. PMID: 24748105; PMCID: PMC4415612.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    98. Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. Neuron. 2014 Apr 16; 82(2):295-307. Cortes CJ, Ling SC, Guo LT, Hung G, Tsunemi T, Ly L, Tokunaga S, Lopez E, Sopher BL, Bennett CF, Shelton GD, Cleveland DW, La Spada AR. PMID: 24742458; PMCID: PMC4096235.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    99. Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):E1035-42. Winkler EA, Sengillo JD, Sagare AP, Zhao Z, Ma Q, Zuniga E, Wang Y, Zhong Z, Sullivan JS, Griffin JH, Cleveland DW, Zlokovic BV. PMID: 24591593; PMCID: PMC3964055.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    100. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21. Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. PMID: 24584051; PMCID: PMC4113004.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansAnimalsCells
    101. Reply to Woodruff et al.: C1q and C3-dependent complement pathway activation does not contribute to disease in SOD1 mutant ALS mice. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E5. Lobsiger CS, Cleveland DW. PMID: 24555201; PMCID: PMC3890793.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    102. Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):829-32. Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK. PMID: 24379375; PMCID: PMC3896192.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansCells
    103. Mitochondrial Isolation and Purification from Mouse Spinal Cord. Bio Protoc. 2013 Nov 05; 3(21). Parone PA, Da Cruz S, Cleveland DW. PMID: 27819013; PMCID: PMC5096646.
      View in: PubMed   Mentions: 2  
    104. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4530-9. Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, Drenner K, Artates JW, McAlonis-Downes M, Markmiller S, Hutt KR, Pizzo DP, Cady J, Harms MB, Baloh RH, Vandenberg SR, Yeo GW, Fu XD, Bennett CF, Cleveland DW, Ravits J. PMID: 24170860; PMCID: PMC3839752.
      View in: PubMed   Mentions: 320     Fields:    Translation:AnimalsCells
    105. C1q induction and global complement pathway activation do not contribute to ALS toxicity in mutant SOD1 mice. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):E4385-92. Lobsiger CS, Boillée S, Pozniak C, Khan AM, McAlonis-Downes M, Lewcock JW, Cleveland DW. PMID: 24170856; PMCID: PMC3831990.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    106. Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):E4134-41. Silk AD, Zasadil LM, Holland AJ, Vitre B, Cleveland DW, Weaver BA. PMID: 24133140; PMCID: PMC3816416.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    107. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS. Mol Ther. 2013 Dec; 21(12):2148-59. Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK. PMID: 24008656; PMCID: PMC3863799.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    108. Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips. Nat Cell Biol. 2013 Sep; 15(9):1079-1088. Gudimchuk N, Vitre B, Kim Y, Kiyatkin A, Cleveland DW, Ataullakhanov FI, Grishchuk EL. PMID: 23955301; PMCID: PMC3919686.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    109. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron. 2013 Aug 07; 79(3):416-38. Ling SC, Polymenidou M, Cleveland DW. PMID: 23931993; PMCID: PMC4411085.
      View in: PubMed   Mentions: 894     Fields:    Translation:HumansAnimals
    110. CENP-A and the CENP nomenclature: response to Talbert and Henikoff. Trends Genet. 2013 Sep; 29(9):500-2. Earnshaw WC, Cleveland DW. PMID: 23910159.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    111. A two-step mechanism for epigenetic specification of centromere identity and function. Nat Cell Biol. 2013 Sep; 15(9):1056-66. Fachinetti D, Folco HD, Nechemia-Arbely Y, Valente LP, Nguyen K, Wong AJ, Zhu Q, Holland AJ, Desai A, Jansen LE, Cleveland DW. PMID: 23873148; PMCID: PMC4418506.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansAnimalsCells
    112. Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. Mol Cell. 2013 Jul 11; 51(1):92-104. Han JS, Holland AJ, Fachinetti D, Kulukian A, Cetin B, Cleveland DW. PMID: 23791783; PMCID: PMC3713096.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    113. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 2013 Apr; 21(2):101-6. Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW. PMID: 23580138; PMCID: PMC3627038.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    114. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci. 2013 May; 16(5):571-9. Kang SH, Li Y, Fukaya M, Lorenzini I, Cleveland DW, Ostrow LW, Rothstein JD, Bergles DE. PMID: 23542689; PMCID: PMC3637847.
      View in: PubMed   Mentions: 291     Fields:    Translation:HumansAnimalsCells
    115. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. J Neurosci. 2013 Mar 13; 33(11):4657-71. Parone PA, Da Cruz S, Han JS, McAlonis-Downes M, Vetto AP, Lee SK, Tseng E, Cleveland DW. PMID: 23486940; PMCID: PMC3711648.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    116. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):E736-45. Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, Shaw CE, Yeo GW, Cleveland DW. PMID: 23382207; PMCID: PMC3581922.
      View in: PubMed   Mentions: 249     Fields:    Translation:AnimalsCells
    117. The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes Dev. 2012 Dec 15; 26(24):2684-9. Holland AJ, Fachinetti D, Zhu Q, Bauer M, Verma IM, Nigg EA, Cleveland DW. PMID: 23249732; PMCID: PMC3533073.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    118. TDP-43 toxicity and the usefulness of junk. Nat Genet. 2012 Dec; 44(12):1289-91. Sun S, Cleveland DW. PMID: 23192178; PMCID: PMC3612973.
      View in: PubMed   Mentions: 2     Fields:    
    119. The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation. J Clin Invest. 2012 Dec; 122(12):4325-8. Holland AJ, Cleveland DW. PMID: 23187131; PMCID: PMC3533566.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    120. Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells. Proc Natl Acad Sci U S A. 2012 Dec 04; 109(49):E3350-7. Holland AJ, Fachinetti D, Han JS, Cleveland DW. PMID: 23150568; PMCID: PMC3523849.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansCells
    121. Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements. Nat Med. 2012 Nov; 18(11):1630-8. Holland AJ, Cleveland DW. PMID: 23135524; PMCID: PMC3616639.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    122. Centrosomes, chromosome instability (CIN) and aneuploidy. Curr Opin Cell Biol. 2012 Dec; 24(6):809-15. Vitre BD, Cleveland DW. PMID: 23127609; PMCID: PMC3621708.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    123. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nat Neurosci. 2012 Nov; 15(11):1488-97. Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, Donohue JP, Shiue L, Bennett CF, Ravits J, Cleveland DW, Yeo GW. PMID: 23023293; PMCID: PMC3586380.
      View in: PubMed   Mentions: 407     Fields:    Translation:HumansAnimalsCells
    124. Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression. Cell. 2012 Aug 31; 150(5):895-908. Yu D, Pendergraff H, Liu J, Kordasiewicz HB, Cleveland DW, Swayze EE, Lima WF, Crooke ST, Prakash TP, Corey DR. PMID: 22939619; PMCID: PMC3444165.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansAnimalsCells
    125. Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation. PLoS One. 2012; 7(8):e42614. Hefferan MP, Galik J, Kakinohana O, Sekerkova G, Santucci C, Marsala S, Navarro R, Hruska-Plochan M, Johe K, Feldman E, Cleveland DW, Marsala M. PMID: 22916141; PMCID: PMC3423406.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    126. Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron. 2012 Jun 21; 74(6):1031-44. Kordasiewicz HB, Stanek LM, Wancewicz EV, Mazur C, McAlonis MM, Pytel KA, Artates JW, Weiss A, Cheng SH, Shihabuddin LS, Hung G, Bennett CF, Cleveland DW. PMID: 22726834; PMCID: PMC3383626.
      View in: PubMed   Mentions: 384     Fields:    Translation:AnimalsCells
    127. Losing balance: the origin and impact of aneuploidy in cancer. EMBO Rep. 2012 Jun 01; 13(6):501-14. Holland AJ, Cleveland DW. PMID: 22565320; PMCID: PMC3367240.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimals
    128. Prion-like spread of protein aggregates in neurodegeneration. J Exp Med. 2012 May 07; 209(5):889-93. Polymenidou M, Cleveland DW. PMID: 22566400; PMCID: PMC3348110.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    129. Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):E1858-67. Kolano A, Brunet S, Silk AD, Cleveland DW, Verlhac MH. PMID: 22552228; PMCID: PMC3390881.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    130. Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab. 2012 May 02; 15(5):778-86. Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW. PMID: 22560226; PMCID: PMC3565468.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    131. Replicating centromeric chromatin: spatial and temporal control of CENP-A assembly. Exp Cell Res. 2012 Jul 15; 318(12):1353-60. Nechemia-Arbely Y, Fachinetti D, Cleveland DW. PMID: 22561213; PMCID: PMC3616609.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    132. Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis. Mol Biol Cell. 2012 May; 23(10):1838-45. Holland AJ, Fachinetti D, Da Cruz S, Zhu Q, Vitre B, Lince-Faria M, Chen D, Parish N, Verma IM, Bettencourt-Dias M, Cleveland DW. PMID: 22456511; PMCID: PMC3350549.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    133. Misregulated RNA processing in amyotrophic lateral sclerosis. Brain Res. 2012 Jun 26; 1462:3-15. Polymenidou M, Lagier-Tourenne C, Hutt KR, Bennett CF, Cleveland DW, Yeo GW. PMID: 22444279; PMCID: PMC3707312.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimals
    134. The seeds of neurodegeneration: prion-like spreading in ALS. Cell. 2011 Oct 28; 147(3):498-508. Polymenidou M, Cleveland DW. PMID: 22036560; PMCID: PMC3220614.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansAnimalsCells
    135. Cancer. Aneuploidy drives a mutator phenotype in cancer. Science. 2011 Aug 19; 333(6045):942-3. Kolodner RD, Cleveland DW, Putnam CD. PMID: 21852477; PMCID: PMC3806716.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    136. Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Curr Opin Neurobiol. 2011 Dec; 21(6):904-19. Da Cruz S, Cleveland DW. PMID: 21813273; PMCID: PMC3228892.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansAnimals
    137. Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. PLoS One. 2011; 6(7):e22031. Vande Velde C, McDonald KK, Boukhedimi Y, McAlonis-Downes M, Lobsiger CS, Bel Hadj S, Zandona A, Julien JP, Shah SB, Cleveland DW. PMID: 21779368; PMCID: PMC3136936.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    138. Centromere identity, function, and epigenetic propagation across cell divisions. Cold Spring Harb Symp Quant Biol. 2010; 75:403-18. Black BE, Jansen LE, Foltz DR, Cleveland DW. PMID: 21467140; PMCID: PMC3140419.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    139. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci. 2011 Apr; 14(4):459-68. Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, Yeo GW, Cleveland DW. PMID: 21358643; PMCID: PMC3094729.
      View in: PubMed   Mentions: 673     Fields:    Translation:HumansAnimalsCells
    140. Epigenetic centromere propagation and the nature of CENP-a nucleosomes. Cell. 2011 Feb 18; 144(4):471-9. Black BE, Cleveland DW. PMID: 21335232; PMCID: PMC3061232.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansAnimalsCells
    141. ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import. Proc Natl Acad Sci U S A. 2010 Dec 07; 107(49):21146-51. Li Q, Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, Capaldi RA, Cleveland DW, Miller TM. PMID: 21078990; PMCID: PMC3000256.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    142. Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol. 2010 Nov 15; 191(4):721-9. Hatch EM, Kulukian A, Holland AJ, Cleveland DW, Stearns T. PMID: 21059850; PMCID: PMC2983069.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    143. How to survive aneuploidy. Cell. 2010 Oct 01; 143(1):27-9. Cetin B, Cleveland DW. PMID: 20887888; PMCID: PMC2955074.
      View in: PubMed   Mentions: 4     Fields:    
    144. Multiclassifier proteomics to define complexes yields new chromosomal proteins. Dev Cell. 2010 Sep 14; 19(3):356-9. Lan W, Cleveland DW. PMID: 20833356; PMCID: PMC2943763.
      View in: PubMed   Mentions:    Fields:    
    145. Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron. 2010 Aug 26; 67(4):575-87. Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW. PMID: 20797535; PMCID: PMC2941987.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansAnimalsCells
    146. Neurodegeneration: An expansion in ALS genetics. Nature. 2010 Aug 26; 466(7310):1052-3. Lagier-Tourenne C, Cleveland DW. PMID: 20740002.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    147. Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell. 2010 Aug 06; 142(3):444-55. Kim Y, Holland AJ, Lan W, Cleveland DW. PMID: 20691903; PMCID: PMC2921712.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    148. Centriole duplication: A lesson in self-control. Cell Cycle. 2010 Jul 15; 9(14):2731-6. Holland AJ, Lan W, Cleveland DW. PMID: 20647763; PMCID: PMC3040958.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    149. A chemical tool box defines mitotic and interphase roles for Mps1 kinase. J Cell Biol. 2010 Jul 12; 190(1):21-4. Lan W, Cleveland DW. PMID: 20624898; PMCID: PMC2911672.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    150. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13318-23. Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW. PMID: 20624952; PMCID: PMC2922163.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansCells
    151. Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes Dev. 2010 May; 24(9):957-71. Gassmann R, Holland AJ, Varma D, Wan X, Civril F, Cleveland DW, Oegema K, Salmon ED, Desai A. PMID: 20439434; PMCID: PMC2861194.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    152. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet. 2010 Apr 15; 19(R1):R46-64. Lagier-Tourenne C, Polymenidou M, Cleveland DW. PMID: 20400460; PMCID: PMC3167692.
      View in: PubMed   Mentions: 494     Fields:    Translation:HumansCells
    153. NuMA after 30 years: the matrix revisited. Trends Cell Biol. 2010 Apr; 20(4):214-22. Radulescu AE, Cleveland DW. PMID: 20137953; PMCID: PMC3137513.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    154. Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. J Cell Biol. 2010 Jan 25; 188(2):191-8. Holland AJ, Lan W, Niessen S, Hoover H, Cleveland DW. PMID: 20100909; PMCID: PMC2813471.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansAnimalsCells
    155. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. J Cell Sci. 2010 Feb 01; 123(Pt 3):321-30. Gurden MD, Holland AJ, van Zon W, Tighe A, Vergnolle MA, Andres DA, Spielmann HP, Malumbres M, Wolthuis RM, Cleveland DW, Taylor SS. PMID: 20053638; PMCID: PMC2816182.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    156. Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J Cell Biol. 2009 Dec 14; 187(6):761-72. Ilieva H, Polymenidou M, Cleveland DW. PMID: 19951898; PMCID: PMC2806318.
      View in: PubMed   Mentions: 539     Fields:    Translation:HumansAnimalsCells
    157. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J Clin Invest. 2009 Nov; 119(11):3437-49. Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. PMID: 19841542; PMCID: PMC2769191.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    158. Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. PLoS One. 2009 Aug 28; 4(8):e6831. Samoshkin A, Arnaoutov A, Jansen LE, Ouspenski I, Dye L, Karpova T, McNally J, Dasso M, Cleveland DW, Strunnikov A. PMID: 19714251; PMCID: PMC2730017.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    159. Double-strand DNA breaks recruit the centromeric histone CENP-A. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15762-7. Zeitlin SG, Baker NM, Chapados BR, Soutoglou E, Wang JY, Berns MW, Cleveland DW. PMID: 19717431; PMCID: PMC2747192.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    160. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol. 2009 Jul; 10(7):478-87. Holland AJ, Cleveland DW. PMID: 19546858; PMCID: PMC3154738.
      View in: PubMed   Mentions: 480     Fields:    Translation:HumansAnimals
    161. The role of aneuploidy in promoting and suppressing tumors. J Cell Biol. 2009 Jun 15; 185(6):935-7. Weaver BA, Cleveland DW. PMID: 19528293; PMCID: PMC2711620.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    162. Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP. Cell. 2009 May 01; 137(3):472-84. Foltz DR, Jansen LE, Bailey AO, Yates JR, Bassett EA, Wood S, Black BE, Cleveland DW. PMID: 19410544; PMCID: PMC2747366.
      View in: PubMed   Mentions: 374     Fields:    Translation:HumansCells
    163. Rethinking ALS: the FUS about TDP-43. Cell. 2009 Mar 20; 136(6):1001-4. Lagier-Tourenne C, Cleveland DW. PMID: 19303844; PMCID: PMC3110083.
      View in: PubMed   Mentions: 274     Fields:    Translation:HumansAnimals
    164. Requirements for NuMA in maintenance and establishment of mammalian spindle poles. J Cell Biol. 2009 Mar 09; 184(5):677-90. Silk AD, Holland AJ, Cleveland DW. PMID: 19255246; PMCID: PMC2686415.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    165. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice. Proc Natl Acad Sci U S A. 2009 Mar 17; 106(11):4465-70. Lobsiger CS, Boillee S, McAlonis-Downes M, Khan AM, Feltri ML, Yamanaka K, Cleveland DW. PMID: 19251638; PMCID: PMC2657393.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    166. Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth. J Neurosci. 2009 Feb 04; 29(5):1277-84. Garcia ML, Rao MV, Fujimoto J, Garcia VB, Shah SB, Crum J, Gotow T, Uchiyama Y, Ellisman M, Calcutt NA, Cleveland DW. PMID: 19193875; PMCID: PMC2782950.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    167. Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway. Hum Mol Genet. 2009 Apr 15; 18(8):1384-94. Cleveland DW, Yamanaka K, Bomont P. PMID: 19168853; PMCID: PMC2664145.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    168. Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Dev Cell. 2009 Jan; 16(1):105-17. Kulukian A, Han JS, Cleveland DW. PMID: 19154722; PMCID: PMC2655205.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansCells
    169. The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell. 2008 Dec 09; 14(6):431-3. Weaver BA, Cleveland DW. PMID: 19061834; PMCID: PMC3132552.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    170. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12599-604. Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. PMID: 18719118; PMCID: PMC2527957.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    171. Beyond genetics: surprising determinants of cell fate in antitumor drugs. Cancer Cell. 2008 Aug 12; 14(2):103-5. Holland AJ, Cleveland DW. PMID: 18691543; PMCID: PMC3132553.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    172. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. PLoS One. 2008 Aug 06; 3(8):e2849. Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. PMID: 18682740; PMCID: PMC2481395.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    173. Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1. J Neurochem. 2008 Oct; 107(1):253-64. Dequen F, Bomont P, Gowing G, Cleveland DW, Julien JP. PMID: 18680552; PMCID: PMC3657508.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    174. Motor neuron disease: The curious ways of ALS. Nature. 2008 Jul 17; 454(7202):284-5. Polymenidou M, Cleveland DW. PMID: 18633404; PMCID: PMC3625042.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    175. Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. PLoS One. 2008 Jun 11; 3(6):e2415. Jelluma N, Brenkman AB, McLeod I, Yates JR, Cleveland DW, Medema RH, Kops GJ. PMID: 18545697; PMCID: PMC2408436.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    176. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7594-9. Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LS. PMID: 18492803; PMCID: PMC2396671.
      View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
    177. CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. J Cell Biol. 2008 May 05; 181(3):411-9. Kim Y, Heuser JE, Waterman CM, Cleveland DW. PMID: 18443223; PMCID: PMC2364708.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    178. ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat Neurosci. 2008 Apr; 11(4):420-2. Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV. PMID: 18344992; PMCID: PMC2895310.
      View in: PubMed   Mentions: 224     Fields:    Translation:HumansAnimalsCells
    179. Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):4022-7. Vande Velde C, Miller TM, Cashman NR, Cleveland DW. PMID: 18296640; PMCID: PMC2268797.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    180. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci. 2008 Mar; 11(3):251-3. Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW. PMID: 18246065; PMCID: PMC3137510.
      View in: PubMed   Mentions: 579     Fields:    Translation:HumansAnimalsCells
    181. Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1. J Clin Invest. 2008 Feb; 118(2):474-8. Boillée S, Cleveland DW. PMID: 18219386; PMCID: PMC2213376.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    182. Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression. Cell Oncol. 2008; 30(5):453. Weaver BA, Silk AD, Cleveland DW. PMID: 18791276; PMCID: PMC4618964.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    183. Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Res. 2007 Nov 01; 67(21):10103-5. Weaver BA, Cleveland DW. PMID: 17974949; PMCID: PMC3132555.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimals
    184. Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease. Nat Neurosci. 2007 Nov; 10(11):1355-60. Lobsiger CS, Cleveland DW. PMID: 17965655; PMCID: PMC3110080.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansAnimalsCells
    185. Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A. Hum Mol Genet. 2008 Feb 01; 17(3):367-75. Detmer SA, Vande Velde C, Cleveland DW, Chan DC. PMID: 17959936.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    186. Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12524-9. Gruzman A, Wood WL, Alpert E, Prasad MD, Miller RG, Rothstein JD, Bowser R, Hamilton R, Wood TD, Cleveland DW, Lingappa VR, Liu J. PMID: 17636119; PMCID: PMC1941502.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    187. RCADiA: simple automation platform for comparative multidimensional protein identification technology. Anal Chem. 2007 Aug 15; 79(16):6410-8. Bailey AO, Miller TM, Dong MQ, Vande Velde C, Cleveland DW, Yates JR. PMID: 17616168; PMCID: PMC2528021.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    188. Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science. 2007 May 18; 316(5827):982; author reply 982. Weaver BA, Cleveland DW. PMID: 17510348.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    189. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nat Med. 2007 Jun; 13(6):754-9. Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A. PMID: 17486090.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    190. CENP-A-containing nucleosomes: easier disassembly versus exclusive centromeric localization. J Mol Biol. 2007 Jul 13; 370(3):555-73. Conde e Silva N, Black BE, Sivolob A, Filipski J, Cleveland DW, Prunell A. PMID: 17524417.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    191. Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7319-26. Lobsiger CS, Boillée S, Cleveland DW. PMID: 17463094; PMCID: PMC1863491.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    192. An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5008-13. Black BE, Brock MA, Bédard S, Woods VL, Cleveland DW. PMID: 17360341; PMCID: PMC1829255.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    193. Propagation of centromeric chromatin requires exit from mitosis. J Cell Biol. 2007 Mar 12; 176(6):795-805. Jansen LE, Black BE, Foltz DR, Cleveland DW. PMID: 17339380; PMCID: PMC2064054.
      View in: PubMed   Mentions: 329     Fields:    Translation:HumansCells
    194. Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Mol Cell. 2007 Jan 26; 25(2):309-22. Black BE, Jansen LE, Maddox PS, Foltz DR, Desai AB, Shah JV, Cleveland DW. PMID: 17244537.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    195. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 2007 Jan; 11(1):25-36. Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. PMID: 17189716.
      View in: PubMed   Mentions: 398     Fields:    Translation:AnimalsCells
    196. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19546-51. Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. PMID: 17164329; PMCID: PMC1748262.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    197. Does aneuploidy cause cancer? Curr Opin Cell Biol. 2006 Dec; 18(6):658-67. Weaver BA, Cleveland DW. PMID: 17046232.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansAnimalsCells
    198. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron. 2006 Oct 05; 52(1):39-59. Boillée S, Vande Velde C, Cleveland DW. PMID: 17015226.
      View in: PubMed   Mentions: 638     Fields:    Translation:HumansAnimalsCells
    199. Intercellular miscommunication in polyglutamine pathogenesis. Nat Neurosci. 2006 Oct; 9(10):1205-6. Ross CA, Cleveland DW. PMID: 17001335.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    200. Amyotrophic lateral sclerosis and gene therapy. Nat Clin Pract Neurol. 2006 Sep; 2(9):462-3. Miller TM, Smith RA, Cleveland DW. PMID: 16932606.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    201. Cell biology: nondisjunction, aneuploidy and tetraploidy. Nature. 2006 Aug 17; 442(7104):E9-10; discussion E10. Weaver BA, Silk AD, Cleveland DW. PMID: 16915240.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    202. Antisense oligonucleotide therapy for neurodegenerative disease. J Clin Invest. 2006 Aug; 116(8):2290-6. Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, Bennett CF, Cleveland DW. PMID: 16878173; PMCID: PMC1518790.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    203. Progressive spinal axonal degeneration and slowness in ALS2-deficient mice. Ann Neurol. 2006 Jul; 60(1):95-104. Yamanaka K, Miller TM, McAlonis-Downes M, Chun SJ, Cleveland DW. PMID: 16802286.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    204. Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. J Neuroimmunol. 2006 Jul; 176(1-2):198-215. Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, Mouradian MM, Przedborski S, Trapp BD, Wyss-Coray T, Yong VW. PMID: 16983747.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    205. Onset and progression in inherited ALS determined by motor neurons and microglia. Science. 2006 Jun 02; 312(5778):1389-92. Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW. PMID: 16741123.
      View in: PubMed   Mentions: 750     Fields:    Translation:HumansAnimalsCells
    206. Novel missense mutation in ALS2 gene results in infantile ascending hereditary spastic paralysis. Ann Neurol. 2006 Jun; 59(6):976-80. Eymard-Pierre E, Yamanaka K, Haeussler M, Kress W, Gauthier-Barichard F, Combes P, Cleveland DW, Boespflug-Tanguy O. PMID: 16718699.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    207. The human CENP-A centromeric nucleosome-associated complex. Nat Cell Biol. 2006 May; 8(5):458-69. Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW. PMID: 16622419.
      View in: PubMed   Mentions: 390     Fields:    Translation:HumansCells
    208. In vivo quantitative studies of dynamic intracellular processes using fluorescence correlation spectroscopy. Biophys J. 2006 Jul 01; 91(1):343-51. Wang Z, Shah JV, Berns MW, Cleveland DW. PMID: 16603490; PMCID: PMC1479085.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    209. Determinants of rapid disease progression in ALS. Neurology. 2005 Dec 27; 65(12):1859-60. Yamanaka K, Cleveland DW. PMID: 16380607.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    210. Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F. EMBO J. 2005 Nov 16; 24(22):3927-39. Bomont P, Maddox P, Shah JV, Desai AB, Cleveland DW. PMID: 16252009; PMCID: PMC1283947.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    211. On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer. 2005 Oct; 5(10):773-85. Kops GJ, Weaver BA, Cleveland DW. PMID: 16195750.
      View in: PubMed   Mentions: 511     Fields:    Translation:HumansCells
    212. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J Cell Biol. 2005 Sep 12; 170(6):873-80. Mao Y, Desai A, Cleveland DW. PMID: 16144904; PMCID: PMC2171436.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    213. Mutations in neurofilament genes are not a significant primary cause of non-SOD1-mediated amyotrophic lateral sclerosis. Neurobiol Dis. 2006 Jan; 21(1):102-9. Garcia ML, Singleton AB, Hernandez D, Ward CM, Evey C, Sapp PA, Hardy J, Brown RH, Cleveland DW. PMID: 16084104.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    214. Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10351-6. Lobsiger CS, Garcia ML, Ward CM, Cleveland DW. PMID: 16002469; PMCID: PMC1177385.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    215. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell. 2005 Jul; 8(1):7-12. Weaver BA, Cleveland DW. PMID: 16023594.
      View in: PubMed   Mentions: 225     Fields:    Translation:HumansCells
    216. Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis. J Neurochem. 2005 May; 93(4):875-82. Liu J, Shinobu LA, Ward CM, Young D, Cleveland DW. PMID: 15857390.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    217. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Ann Neurol. 2005 May; 57(5):773-6. Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. PMID: 15852369; PMCID: PMC1351126.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    218. Merits of a New Drug Trial for ALS? Science. 2005 Apr 29; 308(5722):632b-633b. Beghi E, Bendotti C, Mennini T, Miller T, Cleveland D. PMID: 15863397.
      View in: PubMed   Mentions:    Fields:    
    219. ZW10 links mitotic checkpoint signaling to the structural kinetochore. J Cell Biol. 2005 Apr 11; 169(1):49-60. Kops GJ, Kim Y, Weaver BA, Mao Y, McLeod I, Yates JR, Tagaya M, Cleveland DW. PMID: 15824131; PMCID: PMC1351127.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    220. Medicine. Treating neurodegenerative diseases with antibiotics. Science. 2005 Jan 21; 307(5708):361-2. Miller TM, Cleveland DW. PMID: 15661995.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    221. VEGF: multitasking in ALS. Nat Neurosci. 2005 Jan; 8(1):5-7. Vande Velde C, Cleveland DW. PMID: 15622408.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    222. Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem. 2004 Dec 24; 279(52):54590-8. Wang H, Hu X, Ding X, Dou Z, Yang Z, Shaw AW, Teng M, Cleveland DW, Goldberg ML, Niu L, Yao X. PMID: 15485811.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    223. A standardized kinesin nomenclature. J Cell Biol. 2004 Oct 11; 167(1):19-22. Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L. PMID: 15479732; PMCID: PMC2041940.
      View in: PubMed   Mentions: 317     Fields:    Translation:HumansAnimals
    224. Structural determinants for generating centromeric chromatin. Nature. 2004 Jul 29; 430(6999):578-82. Black BE, Foltz DR, Chakravarthy S, Luger K, Woods VL, Cleveland DW. PMID: 15282608.
      View in: PubMed   Mentions: 183     Fields:    Translation:HumansCells
    225. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 2004 Jul 08; 43(1):5-17. Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. PMID: 15233913.
      View in: PubMed   Mentions: 210     Fields:    Translation:HumansAnimalsCells
    226. Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Curr Biol. 2004 Jun 08; 14(11):942-52. Shah JV, Botvinick E, Bonday Z, Furnari F, Berns M, Cleveland DW. PMID: 15182667.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansAnimalsCells
    227. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8699-704. Kops GJ, Foltz DR, Cleveland DW. PMID: 15159543; PMCID: PMC423258.
      View in: PubMed   Mentions: 203     Fields:    Translation:HumansCells
    228. Gene therapy for ALS delivers. Trends Neurosci. 2004 May; 27(5):235-8. Boillée S, Cleveland DW. PMID: 15111001.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    229. The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease. Neuromolecular Med. 2004; 5(3):193-203. Vande Velde C, Garcia ML, Yin X, Trapp BD, Cleveland DW. PMID: 15626820.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    230. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci. 2004; 27:723-49. Bruijn LI, Miller TM, Cleveland DW. PMID: 15217349.
      View in: PubMed   Mentions: 506     Fields:    Translation:HumansAnimalsCells
    231. Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):16041-6. Yamanaka K, Vande Velde C, Eymard-Pierre E, Bertini E, Boespflug-Tanguy O, Cleveland DW. PMID: 14668431; PMCID: PMC307689.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    232. NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth. J Cell Biol. 2003 Dec 08; 163(5):1011-20. Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, Ward CM, Crawford TO, Gotow T, Uchiyama Y, Ellisman MH, Calcutt NA, Cleveland DW. PMID: 14662745; PMCID: PMC2173620.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    233. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 03; 302(5642):113-7. Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. PMID: 14526083.
      View in: PubMed   Mentions: 405     Fields:    Translation:HumansAnimalsCells
    234. Has gene therapy for ALS arrived? Nat Med. 2003 Oct; 9(10):1256-7. Miller TM, Cleveland DW. PMID: 14520369.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    235. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. J Cell Biol. 2003 Aug 18; 162(4):551-63. Weaver BA, Bonday ZQ, Putkey FR, Kops GJ, Silk AD, Cleveland DW. PMID: 12925705; PMCID: PMC2173788.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    236. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell. 2003 Jul 11; 114(1):87-98. Mao Y, Abrieu A, Cleveland DW. PMID: 12859900.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    237. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol. 2003 Apr 14; 161(1):55-66. Xia CH, Roberts EA, Her LS, Liu X, Williams DS, Cleveland DW, Goldstein LS. PMID: 12682084; PMCID: PMC2172877.
      View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
    238. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell. 2003 Feb 21; 112(4):407-21. Cleveland DW, Mao Y, Sullivan KF. PMID: 12600307.
      View in: PubMed   Mentions: 495     Fields:    Translation:HumansAnimalsCells
    239. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron. 2002 Sep 12; 35(6):1067-83. Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B. PMID: 12354397.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    240. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev Cell. 2002 Sep; 3(3):351-65. Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, Cleveland DW. PMID: 12361599.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    241. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J Cell Biol. 2002 Aug 19; 158(4):681-93. Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW. PMID: 12186852; PMCID: PMC2174004.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    242. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nat Neurosci. 2002 Apr; 5(4):301-7. Subramaniam JR, Lyons WE, Liu J, Bartnikas TB, Rothstein J, Price DL, Cleveland DW, Gitlin JD, Wong PC. PMID: 11889469.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    243. Slow axonal transport: fast motors in the slow lane. Curr Opin Cell Biol. 2002 Feb; 14(1):58-62. Shah JV, Cleveland DW. PMID: 11792545.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    244. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1604-9. Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD. PMID: 11818550; PMCID: PMC122237.
      View in: PubMed   Mentions: 318     Fields:    Translation:HumansAnimals
    245. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J Biol Chem. 2002 Feb 15; 277(7):4644-8. Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. PMID: 11733539.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    246. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci. 2001 Nov; 2(11):806-19. Cleveland DW, Rothstein JD. PMID: 11715057.
      View in: PubMed   Mentions: 519     Fields:    Translation:HumansAnimalsCells
    247. Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell. 2001 Jul 13; 106(1):83-93. Abrieu A, Magnaghi-Jaulin L, Kahana JA, Peter M, Castro A, Vigneron S, Lorca T, Cleveland DW, Labbé JC. PMID: 11461704.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    248. Hypoxia and Lou Gehrig. Nat Genet. 2001 Jun; 28(2):107-8. Skene JP, Cleveland DW. PMID: 11381249.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    249. Cell cycle. Some importin news about spindle assembly. Science. 2001 Mar 02; 291(5509):1718-9. Kahana JA, Cleveland DW. PMID: 11253198.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    250. Formation of advanced glycation end-product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and transgenic mice expressing human SOD1 gene mutation. Neuropathology. 2001 Mar; 21(1):67-81. Kato S, Nakashima K, Horiuchi S, Nagai R, Cleveland DW, Liu J, Hirano A, Takikawa M, Kato M, Nakano I, Sakoda S, Asayama K, Ohama E. PMID: 11304045.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    251. Going new places using an old MAP: tau, microtubules and human neurodegenerative disease. Curr Opin Cell Biol. 2001 Feb; 13(1):41-8. Garcia ML, Cleveland DW. PMID: 11163132.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    252. Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell. 2000 Dec 22; 103(7):997-1000. Shah JV, Cleveland DW. PMID: 11163175.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    253. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13901-6. Pasinelli P, Houseweart MK, Brown RH, Cleveland DW. PMID: 11095709; PMCID: PMC17673.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    254. Oxidation versus aggregation - how do SOD1 mutants cause ALS? Nat Med. 2000 Dec; 6(12):1320-1. Cleveland DW, Liu J. PMID: 11100110.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    255. Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation. J Cell Biol. 2000 Nov 27; 151(5):1013-24. Sánchez I, Hassinger L, Sihag RK, Cleveland DW, Mohan P, Nixon RA. PMID: 11086003; PMCID: PMC2174358.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    256. Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation. Acta Neuropathol. 2000 Nov; 100(5):490-505. Kato S, Horiuchi S, Liu J, Cleveland DW, Shibata N, Nakashima K, Nagai R, Hirano A, Takikawa M, Kato M, Nakano I, Ohama E. PMID: 11045671.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    257. CENP-E as an essential component of the mitotic checkpoint in vitro. Cell. 2000 Sep 15; 102(6):817-26. Abrieu A, Kahana JA, Wood KW, Cleveland DW. PMID: 11030625.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    258. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol. 2000 Aug; 2(8):484-91. Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW. PMID: 10934468.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansCells
    259. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. J Cell Biol. 2000 Jul 10; 150(1):1-11. Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. PMID: 10893249; PMCID: PMC2185570.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    260. New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Jun; 1(3):163-84. Kato S, Takikawa M, Nakashima K, Hirano A, Cleveland DW, Kusaka H, Shibata N, Kato M, Nakano I, Ohama E. PMID: 11464950.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    261. Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J Cell Biol. 2000 May 15; 149(4):851-62. Merdes A, Heald R, Samejima K, Earnshaw WC, Cleveland DW. PMID: 10811826; PMCID: PMC2174573.
      View in: PubMed   Mentions: 155     Fields:    Translation:Cells
    262. Toxicity of ALS-linked SOD1 mutants. Science. 2000 Apr 21; 288(5465):399. Williamson TL, Corson LB, Huang L, Burlingame A, Liu J, Bruijn LI, Cleveland DW. PMID: 10798964.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    263. The value of transgenic models for the study of neurodegenerative diseases. Ann N Y Acad Sci. 2000; 920:179-91. Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. PMID: 11193148.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    264. Cytoskeletal linkers: new MAPs for old destinations. Curr Biol. 1999 Nov 18; 9(22):R864-6. Houseweart MK, Cleveland DW. PMID: 10574751.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    265. From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. Neuron. 1999 Nov; 24(3):515-20. Cleveland DW. PMID: 10595505.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    266. Oxidative stress and iron are implicated in fragmenting vacuoles of Saccharomyces cerevisiae lacking Cu,Zn-superoxide dismutase. J Biol Chem. 1999 Sep 24; 274(39):27590-6. Corson LB, Folmer J, Strain JJ, Culotta VC, Cleveland DW. PMID: 10488097.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    267. Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly. J Cell Biol. 1999 Sep 20; 146(6):1205-10. Kahana JA, Cleveland DW. PMID: 10491385; PMCID: PMC2156118.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    268. Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration. J Neurosci. 1999 Aug 01; 19(15):6446-56. Houseweart MK, Cleveland DW. PMID: 10414973; PMCID: PMC6782803.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    269. Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds. Hum Mol Genet. 1999 Aug; 8(8):1451-60. Ratovitski T, Corson LB, Strain J, Wong P, Cleveland DW, Culotta VC, Borchelt DR. PMID: 10400992.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    270. The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. J Neurochem. 1999 Jan; 72(1):422-9. Rothstein JD, Dykes-Hoberg M, Corson LB, Becker M, Cleveland DW, Price DL, Culotta VC, Wong PC. PMID: 9886096.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    271. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat Neurosci. 1999 Jan; 2(1):50-6. Williamson TL, Cleveland DW. PMID: 10195180.
      View in: PubMed   Mentions: 212     Fields:    Translation:HumansAnimalsCells
    272. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15763-8. Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, Brown RH. PMID: 9861044; PMCID: PMC28118.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    273. Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. J Cell Biol. 1998 Oct 05; 143(1):171-81. Rao MV, Houseweart MK, Williamson TL, Crawford TO, Folmer J, Cleveland DW. PMID: 9763429; PMCID: PMC2132801.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    274. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science. 1998 Sep 18; 281(5384):1851-4. Bruijn LI, Houseweart MK, Kato S, Anderson KL, Anderson SD, Ohama E, Reaume AG, Scott RW, Cleveland DW. PMID: 9743498.
      View in: PubMed   Mentions: 376     Fields:    Translation:HumansAnimalsCells
    275. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9631-6. Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW. PMID: 9689132; PMCID: PMC21390.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    276. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9626-30. Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. PMID: 9689131; PMCID: PMC21389.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    277. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiol Dis. 1998 Jul; 5(1):27-35. Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. PMID: 9702785.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    278. Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6361-6. Corson LB, Strain JJ, Culotta VC, Cleveland DW. PMID: 9600970; PMCID: PMC27707.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    279. Pathogenesis of two axonopathies does not require axonal neurofilaments. Nature. 1998 Feb 05; 391(6667):584-7. Eyer J, Cleveland DW, Wong PC, Peterson AC. PMID: 9468135.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    280. Intermediate filaments and their associated proteins: multiple dynamic personalities. Curr Opin Cell Biol. 1998 Feb; 10(1):93-101. Houseweart MK, Cleveland DW. PMID: 9484600.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    281. A structural scaffolding of intermediate filaments in health and disease. Science. 1998 Jan 23; 279(5350):514-9. Fuchs E, Cleveland DW. PMID: 9438837.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimalsCells
    282. The role of NuMA in the interphase nucleus. J Cell Sci. 1998 Jan; 111 ( Pt 1):71-9. Merdes A, Cleveland DW. PMID: 9394013.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    283. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell. 1997 Oct 31; 91(3):357-66. Wood KW, Sakowicz R, Goldstein LS, Cleveland DW. PMID: 9363944.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansAnimalsCells
    284. The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J Cell Biol. 1997 Oct 20; 139(2):435-47. Yao X, Anderson KL, Cleveland DW. PMID: 9334346; PMCID: PMC2139792.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    285. Pathways of spindle pole formation: different mechanisms; conserved components. J Cell Biol. 1997 Sep 08; 138(5):953-6. Merdes A, Cleveland DW. PMID: 9281574; PMCID: PMC2136757.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    286. CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9165-70. Duesbery NS, Choi T, Brown KD, Wood KW, Resau J, Fukasawa K, Cleveland DW, Vande Woude GF. PMID: 9256453; PMCID: PMC23089.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    287. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7606-11. Bruijn LI, Beal MF, Becher MW, Schulz JB, Wong PC, Price DL, Cleveland DW. PMID: 9207139; PMCID: PMC23869.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    288. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron. 1997 Feb; 18(2):327-38. Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. PMID: 9052802.
      View in: PubMed   Mentions: 467     Fields:    Translation:HumansAnimalsCells
    289. Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport. J Cell Biol. 1996 Nov; 135(3):711-24. Marszalek JR, Williamson TL, Lee MK, Xu Z, Hoffman PN, Becher MW, Crawford TO, Cleveland DW. PMID: 8909545; PMCID: PMC2121055.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    290. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 1996 Nov 01; 87(3):447-58. Merdes A, Ramyar K, Vechio JD, Cleveland DW. PMID: 8898198.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    291. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 1996 Oct; 47(4 Suppl 2):S54-61; discussion S61-2. Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. PMID: 8858052.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    292. Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease. Neuropathol Appl Neurobiol. 1996 Oct; 22(5):373-87. Bruijn LI, Cleveland DW. PMID: 8930947.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    293. Sequence variants in human neurofilament proteins: absence of linkage to familial amyotrophic lateral sclerosis. Ann Neurol. 1996 Oct; 40(4):603-10. Vechio JD, Bruijn LI, Xu Z, Brown RH, Cleveland DW. PMID: 8871580.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    294. An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell. 1996 Aug 23; 86(4):655-65. Yang Y, Dowling J, Yu QC, Kouklis P, Cleveland DW, Fuchs E. PMID: 8752219.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    295. Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H. J Biol Chem. 1996 Aug 23; 271(34):20845-52. Dong DL, Xu ZS, Hart GW, Cleveland DW. PMID: 8702840.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    296. Subunit composition of neurofilaments specifies axonal diameter. J Cell Biol. 1996 Jun; 133(5):1061-9. Xu Z, Marszalek JR, Lee MK, Wong PC, Folmer J, Crawford TO, Hsieh ST, Griffin JW, Cleveland DW. PMID: 8655579; PMCID: PMC2120858.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    297. The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. J Cell Sci. 1996 May; 109 ( Pt 5):961-9. Brown KD, Wood KW, Cleveland DW. PMID: 8743943.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    298. Neuronal growth and death: order and disorder in the axoplasm. Cell. 1996 Mar 08; 84(5):663-6. Cleveland DW. PMID: 8625404.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    299. Neuronal intermediate filaments. Annu Rev Neurosci. 1996; 19:187-217. Lee MK, Cleveland DW. PMID: 8833441.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    300. Motor neuron disease and model systems: aetiologies, mechanisms and therapies. Ciba Found Symp. 1996; 196:3-13; discussion 13-7. Price DL, Koliatsos VE, Wong PC, Pardo CA, Borchelt DR, Lee MK, Cleveland DW, Griffin JW, Hoffman PN, Cork LC, Sisodia SS. PMID: 8866125.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    301. Neurofilaments, radial growth of axons, and mechanisms of motor neuron disease. Cold Spring Harb Symp Quant Biol. 1996; 61:709-23. Williamson TL, Marszalek JR, Vechio JD, Bruijn LI, Lee MK, Xu Z, Brown RH, Cleveland DW. PMID: 9246497.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    302. Neurodegenerative diseases and model systems. Cold Spring Harb Symp Quant Biol. 1996; 61:725-38. Price DL, Borchelt DR, Wong PC, Pardo CA, Thinakaran G, Lee MK, Cleveland DW, Sisodia SS. PMID: 9246498.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    303. Toxic mutants in Charcot's sclerosis. Nature. 1995 Nov 23; 378(6555):342-3. Cleveland DW, Laing N, Hurse PV, Brown RH. PMID: 7477368.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    304. Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. J Cell Biol. 1995 Sep; 130(6):1413-22. Wong PC, Marszalek J, Crawford TO, Xu Z, Hsieh ST, Griffin JW, Cleveland DW. PMID: 7559762; PMCID: PMC2120568.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    305. Overexpression of the p53 gene in primary and metastatic head and neck carcinomas. Laryngoscope. 1995 Jun; 105(6):653-6. Sauter ER, Ridge JA, Trock B, Cleveland D, Whitley KV, Mohr RM, Klein-Szanto A. PMID: 7769953.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    306. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 1995 Jun; 14(6):1105-16. Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. PMID: 7605627.
      View in: PubMed   Mentions: 440     Fields:    Translation:HumansAnimalsCells
    307. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. J Biol Chem. 1995 Feb 17; 270(7):3234-8. Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. PMID: 7852409.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    308. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci U S A. 1995 Feb 14; 92(4):954-8. Pardo CA, Xu Z, Borchelt DR, Price DL, Sisodia SS, Cleveland DW. PMID: 7862672; PMCID: PMC42615.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    309. NuMA: a protein involved in nuclear structure, spindle assembly, and nuclear re-formation. Trends Cell Biol. 1995 Feb; 5(2):60-4. Cleveland DW. PMID: 14731413.
      View in: PubMed   Mentions: 17     Fields:    
    310. Motor neurone disease and animal models. Neurobiol Dis. 1994 Nov; 1(1-2):3-11. Price DL, Cleveland DW, Koliatsos VE. PMID: 9216981.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    311. Regional modulation of neurofilament organization by myelination in normal axons. J Neurosci. 1994 Nov; 14(11 Pt 1):6392-401. Hsieh ST, Kidd GJ, Crawford TO, Xu Z, Lin WM, Trapp BD, Cleveland DW, Griffin JW. PMID: 7965044; PMCID: PMC6577281.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    312. p53 is overexpressed in fifty percent of pre-invasive lesions of head and neck epithelium. Carcinogenesis. 1994 Oct; 15(10):2269-74. Sauter ER, Cleveland D, Trock B, Ridge JA, Klein-Szanto AJ. PMID: 7955065.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    313. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron. 1994 Oct; 13(4):975-88. Lee MK, Marszalek JR, Cleveland DW. PMID: 7946341.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    314. Neuronal intermediate filaments: new progress on an old subject. Curr Opin Neurobiol. 1994 Oct; 4(5):655-61. Xu Z, Dong DL, Cleveland DW. PMID: 7849521.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    315. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8292-6. Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH, Price DL, Sisodia SS, Cleveland DW. PMID: 8058797; PMCID: PMC44592.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansCells
    316. Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. J Cell Biol. 1994 Jun; 125(6):1303-12. Brown KD, Coulson RM, Yen TJ, Cleveland DW. PMID: 8207059; PMCID: PMC2290920.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    317. An amino-terminal tetrapeptide specifies cotranslational degradation of beta-tubulin but not alpha-tubulin mRNAs. Mol Cell Biol. 1994 Jun; 14(6):4076-86. Bachurski CJ, Theodorakis NG, Coulson RM, Cleveland DW. PMID: 8196646; PMCID: PMC358773.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    318. NuMA, a nuclear protein involved in mitosis and nuclear reformation. Curr Opin Cell Biol. 1994 Jun; 6(3):343-6. Compton DA, Cleveland DW. PMID: 7917323.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    319. Characterization of DLC-A and DLC-B, two families of cytoplasmic dynein light chain subunits. Mol Biol Cell. 1994 Jun; 5(6):645-54. Gill SR, Cleveland DW, Schroer TA. PMID: 7949421; PMCID: PMC301080.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    320. Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease. Curr Opin Cell Biol. 1994 Feb; 6(1):34-40. Lee MK, Cleveland DW. PMID: 7513179.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    321. AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm. Nucleic Acids Res. 1994 Jan 25; 22(2):238-46. Katz DA, Theodorakis NG, Cleveland DW, Lindsten T, Thompson CB. PMID: 8121809; PMCID: PMC307777.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    322. The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation. J Cell Biol. 1993 Dec; 123(6 Pt 1):1517-33. Heins S, Wong PC, Müller S, Goldie K, Cleveland DW, Aebi U. PMID: 8253847; PMCID: PMC2290863.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    323. Neurofilaments are obligate heteropolymers in vivo. J Cell Biol. 1993 Sep; 122(6):1337-50. Lee MK, Xu Z, Wong PC, Cleveland DW. PMID: 8376466; PMCID: PMC2119859.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    324. Ferritin synthesis is controlled by iron-dependent translational derepression and by changes in synthesis/transport of nuclear ferritin RNAs. Proc Natl Acad Sci U S A. 1993 Aug 15; 90(16):7613-7. Coulson RM, Cleveland DW. PMID: 8356063; PMCID: PMC47192.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    325. Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M. J Biol Chem. 1993 Aug 05; 268(22):16679-87. Dong DL, Xu ZS, Chevrier MR, Cotter RJ, Cleveland DW, Hart GW. PMID: 8344946.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    326. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell. 1993 Apr 09; 73(1):23-33. Xu Z, Cork LC, Griffin JW, Cleveland DW. PMID: 8462100.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    327. NuMA is required for the proper completion of mitosis. J Cell Biol. 1993 Feb; 120(4):947-57. Compton DA, Cleveland DW. PMID: 8432734; PMCID: PMC2200084.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    328. Involvement of neurofilaments in motor neuron disease. J Cell Sci Suppl. 1993; 17:101-8. Xu Z, Cork LC, Griffin JW, Cleveland DW. PMID: 8144684.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    329. Post-transcriptional processes. Curr Opin Cell Biol. 1992 Dec; 4(6):973-4. Cleveland DW, Hinnebusch AG. PMID: 1485967.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    330. CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature. 1992 Oct 08; 359(6395):536-9. Yen TJ, Li G, Schaar BT, Szilak I, Cleveland DW. PMID: 1406971.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansCells
    331. Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex. Genes Dev. 1992 Oct; 6(10):1927-39. Savant-Bhonsale S, Cleveland DW. PMID: 1398070.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    332. Gamma-tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation. Nature. 1992 Mar 05; 356(6364):80-3. Joshi HC, Palacios MJ, McNamara L, Cleveland DW. PMID: 1538786.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    333. Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis. J Cell Biol. 1992 Mar; 116(6):1395-408. Compton DA, Szilak I, Cleveland DW. PMID: 1541636; PMCID: PMC2289377.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    334. Physical evidence for cotranslational regulation of beta-tubulin mRNA degradation. Mol Cell Biol. 1992 Feb; 12(2):791-9. Theodorakis NG, Cleveland DW. PMID: 1732744; PMCID: PMC364304.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    335. Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol. 1991 Dec; 115(6):1639-50. Gill SR, Schroer TA, Szilak I, Steuer ER, Sheetz MP, Cleveland DW. PMID: 1836789; PMCID: PMC2289205.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    336. Slow axonal transport models come full circle: evidence that microtubule sliding mediates axon elongation and tubulin transport. Cell. 1991 Nov 01; 67(3):453-6. Cleveland DW, Hoffman PN. PMID: 1718604.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    337. Neuronal and glial cytoskeletons. Curr Opin Neurobiol. 1991 Oct; 1(3):346-53. Cleveland DW, Hoffman PN. PMID: 1821676.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    338. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J. 1991 May; 10(5):1245-54. Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW. PMID: 2022189; PMCID: PMC452779.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansCells
    339. Identification of novel centromere/kinetochore-associated proteins using monoclonal antibodies generated against human mitotic chromosome scaffolds. J Cell Biol. 1991 Mar; 112(6):1083-97. Compton DA, Yen TJ, Cleveland DW. PMID: 1999466; PMCID: PMC2288900.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    340. Ability of the c-mos product to associate with and phosphorylate tubulin. Science. 1991 Feb 08; 251(4994):671-5. Zhou RP, Oskarsson M, Paules RS, Schulz N, Cleveland D, Vande Woude GF. PMID: 1825142.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    341. Involvement of neurofilaments in the radial growth of axons. J Cell Sci Suppl. 1991; 15:85-95. Cleveland DW, Monteiro MJ, Wong PC, Gill SR, Gearhart JD, Hoffman PN. PMID: 1824110.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    342. Characterization of dominant and recessive assembly-defective mutations in mouse neurofilament NF-M. J Cell Biol. 1990 Nov; 111(5 Pt 1):1987-2003. Wong PC, Cleveland DW. PMID: 2121743; PMCID: PMC2116320.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    343. Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit. J Cell Biol. 1990 Nov; 111(5 Pt 1):2005-19. Gill SR, Wong PC, Monteiro MJ, Cleveland DW. PMID: 2121744; PMCID: PMC2116331.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    344. Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber. J Cell Biol. 1990 Oct; 111(4):1543-57. Monteiro MJ, Hoffman PN, Gearhart JD, Cleveland DW. PMID: 2120242; PMCID: PMC2116226.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    345. Use of molecular cloning methods to map the distribution of epitopes on topoisomerase I (Scl-70) recognized by sera of scleroderma patients. Arthritis Rheum. 1990 Oct; 33(10):1501-11. D'Arpa P, White-Cooper H, Cleveland DW, Rothfield NF, Earnshaw WC. PMID: 1699543.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    346. Solid adenoid cystic carcinoma of the maxilla. Oral Surg Oral Med Oral Pathol. 1990 Apr; 69(4):470-8. Cleveland D, Abrams AM, Melrose RJ, Handlers JP. PMID: 2158031.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    347. Lung abscess secondary to xanthogranulomatous pyelonephritis. Thorax. 1990 Apr; 45(4):297-9. Pandya K, Wilcox J, Khaw H, Cleveland D, Sharma OP. PMID: 2356557; PMCID: PMC473778.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    348. Tubulin site interpretation. Nature. 1990 Mar 29; 344(6265):389. Cleveland DW, Joshi HC, Murphy DB. PMID: 2138712.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    349. Microtubule MAPping. Cell. 1990 Mar 09; 60(5):701-2. Cleveland DW. PMID: 2107023.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    350. A rapidly rearranging retrotransposon within the miniexon gene locus of Crithidia fasciculata. Mol Cell Biol. 1990 Feb; 10(2):615-24. Gabriel A, Yen TJ, Schwartz DC, Smith CL, Boeke JD, Sollner-Webb B, Cleveland DW. PMID: 2153919; PMCID: PMC360853.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    351. Diversity among tubulin subunits: toward what functional end? Cell Motil Cytoskeleton. 1990; 16(3):159-63. Joshi HC, Cleveland DW. PMID: 2194680.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    352. In vivo discrimination among beta-tubulin isotypes: selective degradation of a type IV beta-tubulin isotype following overexpression in cultured animal cells. New Biol. 1990 Jan; 2(1):66-76. Sisodia SS, Gay DA, Cleveland DW. PMID: 2078553.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    353. The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis. Cell Motil Cytoskeleton. 1990; 17(2):118-32. Lee MK, Tuttle JB, Rebhun LI, Cleveland DW, Frankfurter A. PMID: 2257630.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    354. Gene regulation through messenger RNA stability. Curr Opin Cell Biol. 1989 Dec; 1(6):1148-53. Cleveland DW. PMID: 2699801.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    355. Multiple determinants of eukaryotic mRNA stability. New Biol. 1989 Nov; 1(2):121-6. Cleveland DW, Yen TJ. PMID: 2518709.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    356. Differential utilization of beta-tubulin isotypes in differentiating neurites. J Cell Biol. 1989 Aug; 109(2):663-73. Joshi HC, Cleveland DW. PMID: 2503525; PMCID: PMC2115728.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    357. Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5763-7. Gay DA, Sisodia SS, Cleveland DW. PMID: 2762294; PMCID: PMC297710.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    358. Expression of NF-L and NF-M in fibroblasts reveals coassembly of neurofilament and vimentin subunits. J Cell Biol. 1989 Feb; 108(2):579-93. Monteiro MJ, Cleveland DW. PMID: 2493000; PMCID: PMC2115435.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    359. Autoregulated control of tubulin synthesis in animal cells. Curr Opin Cell Biol. 1989 Feb; 1(1):10-4. Cleveland DW. PMID: 2629858.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    360. Use of DNA transfection to analyze gene regulation and function in animal cells: dissection of the tubulin multigene family. Cell Motil Cytoskeleton. 1989; 14(1):147-55. Cleveland DW. PMID: 2684421.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    361. Autoregulated instability of tubulin mRNAs: a novel eukaryotic regulatory mechanism. Trends Biochem Sci. 1988 Sep; 13(9):339-43. Cleveland DW. PMID: 3072712.
      View in: PubMed   Mentions: 44     Fields:    
    362. Autoregulated instability of beta-tubulin mRNAs by recognition of the nascent amino terminus of beta-tubulin. Nature. 1988 Aug 18; 334(6183):580-5. Yen TJ, Machlin PS, Cleveland DW. PMID: 3405308.
      View in: PubMed   Mentions: 107     Fields:    Translation:Cells
    363. Neurofilament and tubulin expression recapitulates the developmental program during axonal regeneration: induction of a specific beta-tubulin isotype. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4530-3. Hoffman PN, Cleveland DW. PMID: 3132717; PMCID: PMC280464.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    364. A survey of the alpha-tubulin gene family in chicken: unexpected sequence heterogeneity in the polypeptides encoded by five expressed genes. EMBO J. 1988 Apr; 7(4):931-40. Pratt LF, Cleveland DW. PMID: 3267229; PMCID: PMC454418.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    365. cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2543-7. D'Arpa P, Machlin PS, Ratrie H, Rothfield NF, Cleveland DW, Earnshaw WC. PMID: 2833744; PMCID: PMC280033.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    366. Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides. Mol Cell Biol. 1988 Mar; 8(3):1224-35. Yen TJ, Gay DA, Pachter JS, Cleveland DW. PMID: 2835666; PMCID: PMC363267.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    367. Sequence of chicken c beta 7 tubulin. Analysis of a complete set of vertebrate beta-tubulin isotypes. J Mol Biol. 1988 Feb 05; 199(3):439-46. Monteiro MJ, Cleveland DW. PMID: 3351937.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    368. Evidence of discontinuous transcription in the trypanosomatid Crithidia fasciculata. J Biol Chem. 1987 Nov 25; 262(33):16192-9. Gabriel A, Sisodia SS, Cleveland DW. PMID: 3680249.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    369. In vivo coassembly of a divergent beta-tubulin subunit (c beta 6) into microtubules of different function. J Cell Biol. 1987 Nov; 105(5):2179-90. Joshi HC, Yen TJ, Cleveland DW. PMID: 3316249; PMCID: PMC2114845.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    370. Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs. Cell. 1987 Oct 23; 51(2):283-92. Pachter JS, Yen TJ, Cleveland DW. PMID: 2444342.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    371. The sequence and expression of the divergent beta-tubulin in chicken erythrocytes. J Biol Chem. 1987 Oct 15; 262(29):14305-12. Murphy DB, Wallis KT, Machlin PS, Ratrie H, Cleveland DW. PMID: 2888766.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    372. In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens. J Cell Biol. 1987 Oct; 105(4):1707-20. Lopata MA, Cleveland DW. PMID: 3312237; PMCID: PMC2114651.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    373. Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylation. Mol Cell Biol. 1987 Oct; 7(10):3602-12. Sisodia SS, Sollner-Webb B, Cleveland DW. PMID: 3683396; PMCID: PMC368014.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    374. Sequences that confer beta-tubulin autoregulation through modulated mRNA stability reside within exon 1 of a beta-tubulin mRNA. Cell. 1987 Aug 28; 50(5):671-9. Gay DA, Yen TJ, Lau JT, Cleveland DW. PMID: 3621343.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    375. Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B. Proc Natl Acad Sci U S A. 1987 Jul; 84(14):4979-83. Earnshaw WC, Machlin PS, Bordwell BJ, Rothfield NF, Cleveland DW. PMID: 2440036; PMCID: PMC305230.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    376. Neurofilament gene expression: a major determinant of axonal caliber. Proc Natl Acad Sci U S A. 1987 May; 84(10):3472-6. Hoffman PN, Cleveland DW, Griffin JW, Landes PW, Cowan NJ, Price DL. PMID: 3472217; PMCID: PMC304893.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    377. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J Cell Biol. 1987 Apr; 104(4):817-29. Earnshaw WC, Sullivan KF, Machlin PS, Cooke CA, Kaiser DA, Pollard TD, Rothfield NF, Cleveland DW. PMID: 2435739; PMCID: PMC2114438.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansCells
    378. A combination of RNase H and S1 nuclease circumvents an artefact inherent to conventional S1 analysis of RNA splicing. Nucleic Acids Res. 1987 Mar 11; 15(5):1995-2011. Sisodia SS, Cleveland DW, Sollner-Webb B. PMID: 3031584; PMCID: PMC340613.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    379. The multitubulin hypothesis revisited: what have we learned? J Cell Biol. 1987 Mar; 104(3):381-3. Cleveland DW. PMID: 3546332; PMCID: PMC2114543.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    380. A divergent testis-specific alpha-tubulin isotype that does not contain a coded C-terminal tyrosine. Mol Cell Biol. 1987 Jan; 7(1):552-5. Pratt LF, Okamura S, Cleveland DW. PMID: 3561402; PMCID: PMC365103.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    381. Sequence and expression of the chicken beta 5- and beta 4-tubulin genes define a pair of divergent beta-tubulins with complementary patterns of expression. Mol Cell Biol. 1986 Dec; 6(12):4409-18. Sullivan KF, Havercroft JC, Machlin PS, Cleveland DW. PMID: 3025656; PMCID: PMC367223.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    382. Sequence and expression of the chicken beta 3 tubulin gene. A vertebrate testis beta-tubulin isotype. J Biol Chem. 1986 Oct 05; 261(28):13317-22. Sullivan KF, Machlin PS, Ratrie H, Cleveland DW. PMID: 3759966.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    383. RNA polymerase specificity of mRNA production and enhancer action. Proc Natl Acad Sci U S A. 1986 Sep; 83(18):6677-81. Lopata MA, Cleveland DW, Sollner-Webb B. PMID: 3462718; PMCID: PMC386572.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    384. Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4327-31. Sullivan KF, Cleveland DW. PMID: 3459176; PMCID: PMC323725.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    385. Reconstruction of tubulin gene regulation in cultured mammalian cells. Ann N Y Acad Sci. 1986; 466:75-88. Lau JT, Pittenger MF, Havercroft JC, Cleveland DW. PMID: 3460447.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    386. Retention of autoregulatory control of tubulin synthesis in cytoplasts: demonstration of a cytoplasmic mechanism that regulates the level of tubulin expression. J Cell Biol. 1985 Nov; 101(5 Pt 1):1941-52. Pittenger MF, Cleveland DW. PMID: 4055901; PMCID: PMC2113971.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    387. Apparent gene conversion between beta-tubulin genes yields multiple regulatory pathways for a single beta-tubulin polypeptide isotype. Mol Cell Biol. 1985 Sep; 5(9):2454-65. Sullivan KF, Lau JT, Cleveland DW. PMID: 3837190; PMCID: PMC366973.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    388. Reconstruction of appropriate tubulin and actin gene regulation after transient transfection of cloned beta-tubulin and beta-actin genes. Mol Cell Biol. 1985 Jul; 5(7):1611-20. Lau JT, Pittenger MF, Cleveland DW. PMID: 4022009; PMCID: PMC367279.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    389. Molecular biology and genetics of tubulin. Annu Rev Biochem. 1985; 54:331-65. Cleveland DW, Sullivan KF. PMID: 3896122.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    390. Programmed expression of beta-tubulin genes during development and differentiation of the chicken. J Cell Biol. 1984 Dec; 99(6):1927-35. Havercroft JC, Cleveland DW. PMID: 6094589; PMCID: PMC2113537.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    391. Sequence of a highly divergent beta tubulin gene reveals regional heterogeneity in the beta tubulin polypeptide. J Cell Biol. 1984 Nov; 99(5):1754-60. Sullivan KF, Cleveland DW. PMID: 6490718; PMCID: PMC2113369.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    392. High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. Nucleic Acids Res. 1984 Jul 25; 12(14):5707-17. Lopata MA, Cleveland DW, Sollner-Webb B. PMID: 6589587; PMCID: PMC320025.
      View in: PubMed   Mentions: 270     Fields:    Translation:AnimalsCells
    393. Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions. Mol Cell Biol. 1983 Oct; 3(10):1738-45. Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW. PMID: 6646120; PMCID: PMC370035.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    394. Elevation of tubulin levels by microinjection suppresses new tubulin synthesis. Nature. 1983 Oct 20-26; 305(5936):738-40. Cleveland DW, Pittenger MF, Feramisco JR. PMID: 6633643.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    395. The tubulins: from DNA to RNA to protein and back again. Cell. 1983 Sep; 34(2):330-2. Cleveland DW. PMID: 6193888.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    396. Is apparent autoregulatory control of tubulin synthesis nontranscriptionally regulated? J Cell Biol. 1983 Sep; 97(3):919-24. Cleveland DW, Havercroft JC. PMID: 6885926; PMCID: PMC2112582.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    397. Glyceraldehyde 3-phosphate dehydrogenase protein and mRNA are both differentially expressed in adult chickens but not chick embryos. Nucleic Acids Res. 1983 May 25; 11(10):3301-15. Milner RJ, Brow MD, Cleveland DW, Shinnick TM, Sutcliffe JG. PMID: 6687938; PMCID: PMC325964.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    398. Four unique genes required for beta tubulin expression in vertebrates. Cell. 1983 Mar; 32(3):713-24. Lopata MA, Havercroft JC, Chow LT, Cleveland DW. PMID: 6831558.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    399. Autoregulatory control of expression of alpha and beta tubulin. J Submicrosc Cytol. 1983 Jan; 15(1):353-8. Cleveland DW, Pittenger MF, Lopata MA. PMID: 6188853.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    400. Treadmilling of tubulin and actin. Cell. 1982 Apr; 28(4):689-91. Cleveland DW. PMID: 7046949.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    401. Autoregulatory control of the expression of alpha- and beta-tubulins: implications for microtubule assembly. Cold Spring Harb Symp Quant Biol. 1982; 46 Pt 1:171-83. Cleveland D, Kirschner M. PMID: 6286212.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    402. Probing the function of the eucaryotic 5' cap structure by using a monoclonal antibody directed against cap-binding proteins. Cell. 1981 Dec; 27(3 Pt 2):563-72. Sonenberg N, Guertin D, Cleveland D, Trachsel H. PMID: 6101207.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    403. Two distinct classes of keratin genes and their evolutionary significance. Cell. 1981 Nov; 27(1 Pt 2):75-84. Fuchs EV, Coppock SM, Green H, Cleveland DW. PMID: 6173133.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    404. Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell. 1981 Aug; 25(2):537-46. Cleveland DW, Lopata MA, Sherline P, Kirschner MW. PMID: 6116546.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    405. Multiple alpha and beta tubulin genes represent unlinked and dispersed gene families. J Biol Chem. 1981 Mar 25; 256(6):3130-4. Cleveland DW, Hughes SH, Stubblefield E, Kirschner MW, Varmus HE. PMID: 6259149.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    406. Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs. Nature. 1981 Feb 19; 289(5799):650-5. Valenzuela P, Quiroga M, Zaldivar J, Rutter WJ, Kirschner MW, Cleveland DW. PMID: 7464932.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    407. A dispersed multigene family encoding tubulin in Drosophila melanogaster. Cell. 1980 Dec; 22(3):845-54. Sánchez F, Natzle JE, Cleveland DW, Kirschner MW, McCarthy BJ. PMID: 6780200.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    408. Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell. 1980 May; 20(1):95-105. Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW. PMID: 6893015.
      View in: PubMed   Mentions: 511     Fields:    Translation:HumansAnimals
    409. Conservation of microtubule associated proteins. Isolation and characterization of tau and the high molecular weight microtubule associated protein from chicken brain and from mouse fibroblasts and comparison to the corresponding mammalian brain proteins. J Biol Chem. 1979 Dec 25; 254(24):12670-8. Cleveland DW, Spiegelman BM, Kirschner MW. PMID: 227904.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    410. Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products. Cell. 1978 Nov; 15(3):1021-31. Cleveland DW, Kirschner MW, Cowan NJ. PMID: 728983.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    411. Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence. J Cell Biol. 1978 Mar; 76(3):781-6. Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. PMID: 344329; PMCID: PMC2110001.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    412. Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. J Mol Biol. 1977 Oct 25; 116(2):227-47. Cleveland DW, Hwo SY, Kirschner MW. PMID: 146092.
      View in: PubMed   Mentions: 257     Fields:    Translation:Cells
    413. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J Mol Biol. 1977 Oct 25; 116(2):207-25. Cleveland DW, Hwo SY, Kirschner MW. PMID: 599557.
      View in: PubMed   Mentions: 282     Fields:    Translation:Cells
    414. Immunoflourescent staining of cytoplasmic and spindle microtubules in mouse fibroblasts with antibody to tau protein. Proc Natl Acad Sci U S A. 1977 Jun; 74(6):2437-40. Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. PMID: 329285; PMCID: PMC432187.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    415. Tubulin requires tau for growth onto microtubule initiating sites. Proc Natl Acad Sci U S A. 1976 Nov; 73(11):4070-4. Witman GB, Cleveland DW, Weingarten MD, Kirschner MW. PMID: 1069293; PMCID: PMC431332.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
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