Dan Kaufman

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Identification of Novel Regulators of Natural Killer Cell Activity
    NIH R21CA241006Dec 7, 2020 - Nov 30, 2022
    Role: Principal Investigator
    A Rational Systematic Approach to Find Combinations of Pharmacologic and Immune Therapies that Target Identifiable Oncogenic States
    NIH U01CA217885Sep 12, 2017 - Jul 31, 2022
    Role: Co-Principal Investigator
    Blocking NK cell shedding of CD16a to increase cancer cell killing
    NIH R01CA203348Jan 1, 2016 - Mar 31, 2026
    Role: Principal Investigator
    Stem Cell Biology Training Program
    NIH/NIGMS T32GM113846Jul 1, 2015 - Jun 30, 2020
    Role: Co-Principal Investigator
    Osteogenic Repair from Human Pluripotent Stem Cells
    NIH R01DE022556Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Stem Cell Biology Training Program
    NIH T32HD060536Aug 15, 2010 - Jul 31, 2015
    Role: Principal Investigator
    Midwestern Progenitor Cell Consortium
    NIH U01HL100407Sep 30, 2009 - Apr 30, 2017
    Role: Co-Principal Investigator
    Hematopoietic Precursor Development from Human Embryonic Stem (ES) Cells
    NIH R01HL077923Apr 1, 2006 - Mar 31, 2012
    Role: Principal Investigator
    In Vivo Potential of Human ES Cell-Derived Blood Cells
    NIH R21HL072000Sep 30, 2002 - Aug 31, 2005
    Role: Principal Investigator
    Stem Cell Therapy for Myocardial Repair
    NIH R01HL067828Aug 24, 2001 - Sep 30, 2015
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy. Trends Biotechnol. 2023 07; 41(7):907-922. Xue D, Lu S, Zhang H, Zhang L, Dai Z, Kaufman DS, Zhang J. PMID: 36858941.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    2. CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity. Nat Commun. 2022 04 07; 13(1):1899. Bernareggi D, Xie Q, Prager BC, Yun J, Cruz LS, Pham TV, Kim W, Lee X, Coffey M, Zalfa C, Azmoon P, Zhu H, Tamayo P, Rich JN, Kaufman DS. PMID: 35393416; PMCID: PMC8990014.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    3. iPSC-Derived Natural Killer Cell Therapies - Expansion and Targeting. Front Immunol. 2022; 13:841107. Goldenson BH, Hor P, Kaufman DS. PMID: 35185932; PMCID: PMC8851389.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    4. Disease-associated mutations in topoisomerase IIβ result in defective NK cells. J Allergy Clin Immunol. 2022 06; 149(6):2171-2176.e3. Broderick L, Clay GM, Blum RH, Liu Y, McVicar R, Papes F, Booshehri LM, Cowell IG, Austin CA, Putnam CD, Kaufman DS. PMID: 35063500.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    5. Into the multiverse of gene edited NK cell-based therapeutic strategies. Cell Stem Cell. 2021 12 02; 28(12):2041-2043. Goldenson BH, Kaufman DS. PMID: 34861144.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    6. Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. Stem Cells. 2021 12; 39(12):1701-1717. Pouyanfard S, Meshgin N, Cruz LS, Diggle K, Hashemi H, Pham TV, Fierro M, Tamayo P, Fanjul A, Kisseleva T, Kaufman DS. PMID: 34460131.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    7. iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy. Sci Transl Med. 2020 11 04; 12(568). Cichocki F, Bjordahl R, Gaidarova S, Mahmood S, Abujarour R, Wang H, Tuininga K, Felices M, Davis ZB, Bendzick L, Clarke R, Stokely L, Rogers P, Ge M, Robinson M, Rezner B, Robbins DL, Lee TT, Kaufman DS, Blazar BR, Valamehr B, Miller JS. PMID: 33148626; PMCID: PMC8861807.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    8. Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles. Front Immunol. 2020; 11:561553. Goldenson BH, Zhu H, Wang YM, Heragu N, Bernareggi D, Ruiz-Cisneros A, Bahena A, Ask EH, Hoel HJ, Malmberg KJ, Kaufman DS. PMID: 33178188; PMCID: PMC7593774.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    9. Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity. Cell Stem Cell. 2020 08 06; 27(2):224-237.e6. Zhu H, Blum RH, Bernareggi D, Ask EH, Wu Z, Hoel HJ, Meng Z, Wu C, Guan KL, Malmberg KJ, Kaufman DS. PMID: 32531207; PMCID: PMC7415618.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    10. Lineage-specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1-RUNX2 association in neural crest-derived osteoprogenitors. Stem Cells. 2020 09; 38(9):1107-1123. Kidwai F, Mui BWH, Arora D, Iqbal K, Hockaday M, de Castro Diaz LF, Cherman N, Martin D, Myneni VD, Ahmad M, Futrega K, Ali S, Merling RK, Kaufman DS, Lee J, Robey PG. PMID: 32442326; PMCID: PMC7484058.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. Pluripotent stem cell-derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity. Blood. 2020 02 06; 135(6):399-410. Zhu H, Blum RH, Bjordahl R, Gaidarova S, Rogers P, Lee TT, Abujarour R, Bonello GB, Wu J, Tsai PF, Miller JS, Walcheck B, Valamehr B, Kaufman DS. PMID: 31856277; PMCID: PMC7005364.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    12. Outcomes and Cost-Effectiveness of Autologous Hematopoietic Cell Transplant for Multiple Sclerosis. Curr Treat Options Neurol. 2019 Oct 17; 21(10):53. Dunn-Pirio AM, Heyman BM, Kaufman DS, Kinkel RP. PMID: 31624926.
      View in: PubMed   Mentions: 4  
    13. Engineered human pluripotent stem cell-derived natural killer cells: the next frontier for cancer immunotherapy. Blood Sci. 2019 Aug; 1(1):4-11. Zhu H, Kaufman DS. PMID: 35402797; PMCID: PMC8974906.
      View in: PubMed   Mentions: 8  
    14. Development of innate immune cells from human pluripotent stem cells. Exp Hematol. 2019 03; 71:13-23. Bernareggi D, Pouyanfard S, Kaufman DS. PMID: 30611869; PMCID: PMC6401218.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    15. An Improved Method to Produce Clinical-Scale Natural Killer Cells from Human Pluripotent Stem Cells. Methods Mol Biol. 2019; 2048:107-119. Zhu H, Kaufman DS. PMID: 31396935.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    16. Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells. Front Immunol. 2018; 9:2873. Snyder KM, Hullsiek R, Mishra HK, Mendez DC, Li Y, Rogich A, Kaufman DS, Wu J, Walcheck B. PMID: 30574146; PMCID: PMC6291448.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    17. Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells. Semin Immunopathol. 2019 01; 41(1):59-68. Saetersmoen ML, Hammer Q, Valamehr B, Kaufman DS, Malmberg KJ. PMID: 30361801.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    18. Advances in the role of the aryl hydrocarbon receptor to regulate early hematopoietic development. Curr Opin Hematol. 2018 07; 25(4):273-278. Angelos MG, Kaufman DS. PMID: 29697485.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    19. Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity. Cell Stem Cell. 2018 Aug 02; 23(2):181-192.e5. Li Y, Hermanson DL, Moriarity BS, Kaufman DS. PMID: 30082067; PMCID: PMC6084450.
      View in: PubMed   Mentions: 397     Fields:    Translation:HumansAnimalsCells
    20. Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy. Stem Cells. 2018 02; 36(2):134-145. Zhu H, Lai YS, Li Y, Blum RH, Kaufman DS. PMID: 29235195; PMCID: PMC5914526.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    21. Single Cell Resolution of Human Hematoendothelial Cells Defines Transcriptional Signatures of Hemogenic Endothelium. Stem Cells. 2018 02; 36(2):206-217. Angelos MG, Abrahante JE, Blum RH, Kaufman DS. PMID: 29139170; PMCID: PMC5914515.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    22. Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells. Blood. 2017 06 29; 129(26):3428-3439. Angelos MG, Ruh PN, Webber BR, Blum RH, Ryan CD, Bendzick L, Shim S, Yingst AM, Tufa DM, Verneris MR, Kaufman DS. PMID: 28533309; PMCID: PMC5492090.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    23. Fibrinogen Induces RUNX2 Activity and Osteogenic Development from Human Pluripotent Stem Cells. Stem Cells. 2016 08; 34(8):2079-89. Kidwai F, Edwards J, Zou L, Kaufman DS. PMID: 27331788; PMCID: PMC5097445.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Angiogenic activity mediates bone repair from human pluripotent stem cell-derived osteogenic cells. Sci Rep. 2016 Mar 16; 6:22868. Zou L, Chen Q, Quanbeck Z, Bechtold JE, Kaufman DS. PMID: 26980556; PMCID: PMC4793227.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. Mouse Xenograft Model for Intraperitoneal Administration of NK Cell Immunotherapy for Ovarian Cancer. Methods Mol Biol. 2016; 1441:277-84. Hermanson DL, Bendzick L, Kaufman DS. PMID: 27177674.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    26. Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer. Stem Cells. 2016 Jan; 34(1):93-101. Hermanson DL, Bendzick L, Pribyl L, McCullar V, Vogel RI, Miller JS, Geller MA, Kaufman DS. PMID: 26503833; PMCID: PMC4713309.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    27. Pluripotent stem cell applications for regenerative medicine. Curr Opin Organ Transplant. 2015 Dec; 20(6):663-70. Angelos MG, Kaufman DS. PMID: 26536430; PMCID: PMC4635470.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    28. Efficient generation of endothelial cells from human pluripotent stem cells and characterization of their functional properties. J Biomed Mater Res A. 2016 03; 104(3):678-687. Song W, Kaufman DS, Shen W. PMID: 26519950.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    29. Silent IL2RG Gene Editing in Human Pluripotent Stem Cells. Mol Ther. 2016 Mar; 24(3):582-91. Li LB, Ma C, Awong G, Kennedy M, Gornalusse G, Keller G, Kaufman DS, Russell DW. PMID: 26444081; PMCID: PMC4786911.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Utilizing chimeric antigen receptors to direct natural killer cell activity. Front Immunol. 2015; 6:195. Hermanson DL, Kaufman DS. PMID: 25972867; PMCID: PMC4412125.
      View in: PubMed   Mentions: 88     Fields:    
    31. The RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cells. Stem Cells. 2015 Apr; 33(4):1130-41. Ferrell PI, Xi J, Ma C, Adlakha M, Kaufman DS. PMID: 25546363; PMCID: PMC4751882.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    32. Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells. PLoS One. 2015; 10(3):e0121788. Jing Y, Ni Z, Wu J, Higgins L, Markowski TW, Kaufman DS, Walcheck B. PMID: 25816339; PMCID: PMC4376770.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    33. Use of RUNX2 expression to identify osteogenic progenitor cells derived from human embryonic stem cells. Stem Cell Reports. 2015 Feb 10; 4(2):190-8. Zou L, Kidwai FK, Kopher RA, Motl J, Kellum CA, Westendorf JJ, Kaufman DS. PMID: 25680477; PMCID: PMC4325195.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    34. Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells. Cell Stem Cell. 2014 Dec 04; 15(6):750-61. Ye L, Chang YH, Xiong Q, Zhang P, Zhang L, Somasundaram P, Lepley M, Swingen C, Su L, Wendel JS, Guo J, Jang A, Rosenbush D, Greder L, Dutton JR, Zhang J, Kamp TJ, Kaufman DS, Ge Y, Zhang J. PMID: 25479750; PMCID: PMC4275050.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    35. Expression of chimeric receptor CD4ζ by natural killer cells derived from human pluripotent stem cells improves in vitro activity but does not enhance suppression of HIV infection in vivo. Stem Cells. 2014 Apr; 32(4):1021-31. Ni Z, Knorr DA, Bendzick L, Allred J, Kaufman DS. PMID: 24307574; PMCID: PMC3960346.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    36. Functional assessment of hematopoietic niche cells derived from human embryonic stem cells. Stem Cells Dev. 2014 Jun 15; 23(12):1355-63. Ferrell PI, Hexum MK, Kopher RA, Lepley MA, Gussiaas A, Kaufman DS. PMID: 24517837; PMCID: PMC4046207.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    37. Intraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model. Cytotherapy. 2013 Oct; 15(10):1297-306. Geller MA, Knorr DA, Hermanson DA, Pribyl L, Bendzick L, McCullar V, Miller JS, Kaufman DS. PMID: 23993303; PMCID: PMC3775496.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    38. Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood. 2013 Jun 27; 121(26):5252-3. Ran D, Lam K, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. PMID: 23813938; PMCID: PMC3695367.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    39. Development, expansion, and in vivo monitoring of human NK cells from human embryonic stem cells (hESCs) and and induced pluripotent stem cells (iPSCs). J Vis Exp. 2013 Apr 23; (74):e50337. Bock AM, Knorr D, Kaufman DS. PMID: 23644738; PMCID: PMC3667548.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    40. Heterodimeric bispecific single-chain variable-fragment antibodies against EpCAM and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells. Cancer Biother Radiopharm. 2013 May; 28(4):274-82. Vallera DA, Zhang B, Gleason MK, Oh S, Weiner LM, Kaufman DS, McCullar V, Miller JS, Verneris MR. PMID: 23611188; PMCID: PMC4209492.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    41. Engineered human embryonic stem cell-derived lymphocytes to study in vivo trafficking and immunotherapy. Stem Cells Dev. 2013 Jul 01; 22(13):1861-9. Knorr DA, Bock A, Brentjens RJ, Kaufman DS. PMID: 23421330; PMCID: PMC3685314.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    42. Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy. Stem Cells Transl Med. 2013 Apr; 2(4):274-83. Knorr DA, Ni Z, Hermanson D, Hexum MK, Bendzick L, Cooper LJ, Lee DA, Kaufman DS. PMID: 23515118; PMCID: PMC3659832.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    43. Tu-mor(e) blood cells from human pluripotent stem cells. Blood. 2013 Feb 21; 121(8):1245-6. Kaufman DS. PMID: 23429981.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    44. RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood. 2013 Apr 11; 121(15):2882-90. Ran D, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. PMID: 23372166; PMCID: PMC3624936.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    45. Functional consequences of human induced pluripotent stem cell therapy: myocardial ATP turnover rate in the in vivo swine heart with postinfarction remodeling. Circulation. 2013 Mar 05; 127(9):997-1008. Xiong Q, Ye L, Zhang P, Lepley M, Tian J, Li J, Zhang L, Swingen C, Vaughan JT, Kaufman DS, Zhang J. PMID: 23371930; PMCID: PMC3980462.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    46. Pluripotent stem cells and gene therapy. Transl Res. 2013 Apr; 161(4):284-92. Simara P, Motl JA, Kaufman DS. PMID: 23353080; PMCID: PMC3602131.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. Hematopoietic and nature killer cell development from human pluripotent stem cells. Methods Mol Biol. 2013; 1029:33-41. Ni Z, Knorr DA, Kaufman DS. PMID: 23756940.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    48. Bioenergetic and functional consequences of cellular therapy: activation of endogenous cardiovascular progenitor cells. Circ Res. 2012 Aug 03; 111(4):455-68. Xiong Q, Ye L, Zhang P, Lepley M, Swingen C, Zhang L, Kaufman DS, Zhang J. PMID: 22723295; PMCID: PMC3635674.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    49. Concise review: Cord blood banking, transplantation and induced pluripotent stem cell: success and opportunities. Stem Cells. 2012 Jan; 30(1):55-60. Rao M, Ahrlund-Richter L, Kaufman DS. PMID: 22069231.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    50. Erythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PLoS One. 2011; 6(12):e29110. Sjeklocha LM, Park CW, Wong PY, Roney MJ, Belcher JD, Kaufman DS, Vercellotti GM, Hebbel RP, Steer CJ. PMID: 22216176; PMCID: PMC3247234.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    51. Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer. Mol Cancer Ther. 2011 Oct; 10(10):1829-38. Waldron NN, Kaufman DS, Oh S, Inde Z, Hexum MK, Ohlfest JR, Vallera DA. PMID: 21862685; PMCID: PMC3191276.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    52. A synthetic substrate to support early mesodermal differentiation of human embryonic stem cells. Biomaterials. 2011 Nov; 32(32):8058-66. Liu Y, Wang X, Kaufman DS, Shen W. PMID: 21821284; PMCID: PMC3189998.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow. J Orthop Res. 2011 Dec; 29(12):1804-11. Undale A, Fraser D, Hefferan T, Kopher RA, Herrick J, Evans GL, Li X, Kakar S, Hayes M, Atkinson E, Yaszemski MJ, Kaufman DS, Westendorf JJ, Khosla S. PMID: 21674605; PMCID: PMC3179810.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    54. Extramedullary relapse of acute myelogenous leukemia after allogeneic hematopoietic stem cell transplantation: better prognosis than systemic relapse. Biol Blood Marrow Transplant. 2012 Jan; 18(1):106-12. Solh M, DeFor TE, Weisdorf DJ, Kaufman DS. PMID: 21703975.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    55. A fibrin patch-based enhanced delivery of human embryonic stem cell-derived vascular cell transplantation in a porcine model of postinfarction left ventricular remodeling. Stem Cells. 2011 Feb; 29(2):367-75. Xiong Q, Hill KL, Li Q, Suntharalingam P, Mansoor A, Wang X, Jameel MN, Zhang P, Swingen C, Kaufman DS, Zhang J. PMID: 21732493; PMCID: PMC3412592.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    56. In vivo evaluation of putative hematopoietic stem cells derived from human pluripotent stem cells. Methods Mol Biol. 2011; 767:433-47. Hexum MK, Tian X, Kaufman DS. PMID: 21822894.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    57. Methotrexate supports in vivo selection of human embryonic stem cell derived-hematopoietic cells expressing dihydrofolate reductase. Bioeng Bugs. 2010 Nov-Dec; 1(6):434-6. Gori JL, McIvor RS, Kaufman DS. PMID: 21468213; PMCID: PMC3056096.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    58. Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms. J Virol. 2011 Jan; 85(1):43-50. Ni Z, Knorr DA, Clouser CL, Hexum MK, Southern P, Mansky LM, Park IH, Kaufman DS. PMID: 20962093; PMCID: PMC3014194.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    59. Use of human embryonic stem cells to understand hematopoiesis and hematopoietic stem cell niche. Curr Stem Cell Res Ther. 2010 Sep; 5(3):245-50. Islam MS, Ni Z, Kaufman DS. PMID: 20214557.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    60. Pluripotent stem cell-derived natural killer cells for cancer therapy. Transl Res. 2010 Sep; 156(3):147-54. Knorr DA, Kaufman DS. PMID: 20801411; PMCID: PMC2932648.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    61. Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. Bone. 2010 Oct; 47(4):718-28. Kopher RA, Penchev VR, Islam MS, Hill KL, Khosla S, Kaufman DS. PMID: 20601304; PMCID: PMC2939152.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    62. Human embryonic stem cell-derived vascular progenitor cells capable of endothelial and smooth muscle cell function. Exp Hematol. 2010 Mar; 38(3):246-257.e1. Hill KL, Obrtlikova P, Alvarez DF, King JA, Keirstead SA, Allred JR, Kaufman DS. PMID: 20067819; PMCID: PMC2838385.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    63. Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells. Stem Cells. 2009 Nov; 27(11):2675-85. Tian X, Hexum MK, Penchev VR, Taylor RJ, Shultz LD, Kaufman DS. PMID: 19711457; PMCID: PMC2857550.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    64. In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase. Gene Ther. 2010 Feb; 17(2):238-49. Gori JL, Tian X, Swanson D, Gunther R, Shultz LD, McIvor RS, Kaufman DS. PMID: 19829316; PMCID: PMC2820606.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    65. Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells. Blood. 2009 Oct 22; 114(17):3513-23. Kaufman DS. PMID: 19652198; PMCID: PMC2766673.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    66. Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome. J Clin Oncol. 2009 Aug 01; 27(22):3634-41. Tomblyn MB, Arora M, Baker KS, Blazar BR, Brunstein CG, Burns LJ, DeFor TE, Dusenbery KE, Kaufman DS, Kersey JH, MacMillan ML, McGlave PB, Miller JS, Orchard PJ, Slungaard A, Tomblyn MR, Vercellotti GM, Verneris MR, Wagner JE, Weisdorf DJ. PMID: 19581540; PMCID: PMC2720079.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    67. Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity. Blood. 2009 Jun 11; 113(24):6094-101. Woll PS, Grzywacz B, Tian X, Marcus RK, Knorr DA, Verneris MR, Kaufman DS. PMID: 19365083; PMCID: PMC2699231.
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    68. Hematopoietic differentiation of human embryonic stem cells by cocultivation with stromal layers. Curr Protoc Stem Cell Biol. 2008 Sep; Chapter 1:Unit 1F.6. Hill KL, Kaufman DS. PMID: 18819084.
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    69. Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood-derived hematopoietic progenitor cells. Blood. 2008 Oct 01; 112(7):2730-7. Martin CH, Woll PS, Ni Z, Zúñiga-Pflücker JC, Kaufman DS. PMID: 18621931; PMCID: PMC2556609.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    70. Differentiation of embryonic stem cells towards hematopoietic cells: progress and pitfalls. Curr Opin Hematol. 2008 Jul; 15(4):312-8. Tian X, Kaufman DS. PMID: 18536568.
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    71. Activation of hypoxic response in human embryonic stem cell-derived embryoid bodies. Exp Biol Med (Maywood). 2008 Aug; 233(8):1044-57. Cameron CM, Harding F, Hu WS, Kaufman DS. PMID: 18535160.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    72. Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells. Stem Cells Dev. 2008 Apr; 17(2):325-32. Bera TK, Saint Fleur A, Ha D, Yamada M, Lee Y, Lee B, Hahn Y, Kaufman DS, Pera M, Pastan I. PMID: 18447647; PMCID: PMC7233169.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    73. Reduced-intensity allogeneic transplant in patients older than 55 years: unrelated umbilical cord blood is safe and effective for patients without a matched related donor. Biol Blood Marrow Transplant. 2008 Mar; 14(3):282-9. Majhail NS, Brunstein CG, Tomblyn M, Thomas AJ, Miller JS, Arora M, Kaufman DS, Burns LJ, Slungaard A, McGlave PB, Wagner JE, Weisdorf DJ. PMID: 18275894; PMCID: PMC2674378.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCTClinical Trials
    74. Hematopoietic development of human embryonic stem cells in culture. Methods Mol Biol. 2008; 430:119-33. Tian X, Kaufman DS. PMID: 18370295.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    75. Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells. Blood. 2008 Jan 01; 111(1):122-31. Woll PS, Morris JK, Painschab MS, Marcus RK, Kohn AD, Biechele TL, Moon RT, Kaufman DS. PMID: 17875805; PMCID: PMC2200802.
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    76. Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transfer. Stem Cells. 2007 Nov; 25(11):2919-27. Wilber A, Linehan JL, Tian X, Woll PS, Morris JK, Belur LR, McIvor RS, Kaufman DS. PMID: 17673526.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    77. Donor cell leukemia: insight into cancer stem cells and the stem cell niche. Blood. 2007 Apr 01; 109(7):2688-92. Flynn CM, Kaufman DS. PMID: 17132724.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    78. Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation. Biotechnol Bioeng. 2006 Aug 05; 94(5):938-48. Cameron CM, Hu WS, Kaufman DS. PMID: 16547998.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    79. Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy. Retrovirology. 2006 Apr 19; 3:24. Anderson JS, Bandi S, Kaufman DS, Akkina R. PMID: 16623949; PMCID: PMC1462997.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    80. Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells. 2006 May; 24(5):1370-80. Tian X, Woll PS, Morris JK, Linehan JL, Kaufman DS. PMID: 16456127.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    81. Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development. Exp Hematol. 2005 Dec; 33(12):1450-8. Qiu C, Hanson E, Olivier E, Inada M, Kaufman DS, Gupta S, Bouhassira EE. PMID: 16338487.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    82. Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem Cells Dev. 2005 Dec; 14(6):643-55. Schwartz RE, Linehan JL, Painschab MS, Hu WS, Verfaillie CM, Kaufman DS. PMID: 16433619.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    83. Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood. 2006 Mar 01; 107(5):2180-3. Narayan AD, Chase JL, Lewis RL, Tian X, Kaufman DS, Thomson JA, Zanjani ED. PMID: 16278307; PMCID: PMC1895718.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    84. Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. J Immunol. 2005 Oct 15; 175(8):5095-103. Woll PS, Martin CH, Miller JS, Kaufman DS. PMID: 16210613.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    85. Synergistic use of adult and embryonic stem cells to study human hematopoiesis. Curr Opin Biotechnol. 2005 Oct; 16(5):510-5. Martin CH, Kaufman DS. PMID: 16095900.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    86. Nonhuman primate embryonic stem cells as a preclinical model for hematopoietic and vascular repair. Exp Hematol. 2005 Sep; 33(9):980-6. Hematti P, Obrtlikova P, Kaufman DS. PMID: 16140145.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    87. Hematopoietic development of human embryonic stem cells in culture. Methods Mol Biol. 2005; 290:149-62. Tian X, Kaufman DS. PMID: 15361661.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    88. Hematopoietic development of human embryonic stem cells in culture. Methods Mol Med. 2005; 105:425-36. Tian X, Kaufman DS. PMID: 15492412.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    89. Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells. Exp Hematol. 2004 Oct; 32(10):1000-9. Tian X, Morris JK, Linehan JL, Kaufman DS. PMID: 15504555.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    90. Efficient transfection of embryonic and adult stem cells. Stem Cells. 2004; 22(4):531-43. Lakshmipathy U, Pelacho B, Sudo K, Linehan JL, Coucouvanis E, Kaufman DS, Verfaillie CM. PMID: 15277699.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    91. Mouse and human embryonic stem cell models of hematopoiesis: past, present, and future. Biotechniques. 2003 Dec; 35(6):1253-61. Chen D, Lewis RL, Kaufman DS. PMID: 14682061.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    92. Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood. 2004 Feb 15; 103(4):1325-32. Kaufman DS, Lewis RL, Hanson ET, Auerbach R, Plendl J, Thomson JA. PMID: 14563647.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    93. Multilineage differentiation from human embryonic stem cell lines. Stem Cells. 2001; 19(3):193-204. Odorico JS, Kaufman DS, Thomson JA. PMID: 11359944.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansCells
    94. MHC class I expression on tumor targets inhibits natural killer cell-mediated cytotoxicity without interfering with target recognition. J Immunol. 1993 Feb 15; 150(4):1429-36. Kaufman DS, Schoon RA, Leibson PJ. PMID: 8432986.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    95. Role for major histocompatibility complex class I in regulating natural killer cell-mediated killing of virus-infected cells. Proc Natl Acad Sci U S A. 1992 Sep 01; 89(17):8337-41. Kaufman DS, Schoon RA, Leibson PJ. PMID: 1325654; PMCID: PMC49913.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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