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Francesca Telese

Title(s)Assistant Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0648
La Jolla CA 92093
Phone858-246-2607
ORCID ORCID Icon0000-0003-3877-0628 Additional info
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    Collapse Biography 
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    University of Naples Federico II, ItalyPh.D.2007Neuroscience

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    My lab studies how the environment influences brain function in health and disease. We approach this broad question by studying epigenetic modifications that store the molecular responses of a cell to its environment. Our major focus is understanding epigenetic mechanisms underlying cell-type specific gene expression. We use next-generation sequencing techniques in cellular systems or model organisms. The identification and manipulation of epigenetic processes in the brain may enhance our basic understanding of brain function and open the door to new treatments for brain diseases.

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    Epigenomic approaches to study the gene networks underlying the cannabis effects on genetic vulnerability to psychosis
    NIH DP1DA042232Jun 1, 2016 - Apr 30, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. Addict Biol. 2020 Mar 18; e12896. Caffino L, Mottarlini F, Van Reijmersdal B, Telese F, Verheij MMM, Fumagalli F, Homberg JR. PMID: 32187792.
      View in: PubMed   Mentions:    Fields:    
    2. A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain. J Comp Neurol. 2020 Sep 01; 528(13):2218-2238. Iemolo A, Montilla-Perez P, Lai IC, Meng Y, Nolan S, Wen J, Rusu I, Dulcis D, Telese F. PMID: 32072640.
      View in: PubMed   Mentions: 1     Fields:    
    3. Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia. Neurobiol Dis. 2019 10; 130:104502. Swinton MK, Carson A, Telese F, Sanchez AB, Soontornniyomkij B, Rad L, Batki I, Quintanilla B, Pérez-Santiago J, Achim CL, Letendre S, Ellis RJ, Grant I, Murphy AN, Fields JA. PMID: 31238091.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERa-Regulated Transcriptional Program. Mol Cell. 2017 May 04; 66(3):321-331.e6. Yang F, Ma Q, Liu Z, Li W, Tan Y, Jin C, Ma W, Hu Y, Shen J, Ohgi KA, Telese F, Liu W, Rosenfeld MG. PMID: 28475868.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    5. Genome-wide epigenetic analysis of MEF2A and MEF2C transcription factors in mouse cortical neurons. Commun Integr Biol. 2015 Nov-Dec; 8(6):e1087624. Ma Q, Telese F. PMID: 27066173.
      View in: PubMed   Mentions:
    6. LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control. Nat Neurosci. 2015 Sep; 18(9):1256-64. Wang J, Telese F, Tan Y, Li W, Jin C, He X, Basnet H, Ma Q, Merkurjev D, Zhu X, Liu Z, Zhang J, Ohgi K, Taylor H, White RR, Tazearslan C, Suh Y, Macfarlan TS, Pfaff SL, Rosenfeld MG. PMID: 26214369.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    7. LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron. 2015 May 06; 86(3):696-710. Telese F, Ma Q, Perez PM, Notani D, Oh S, Li W, Comoletti D, Ohgi KA, Taylor H, Rosenfeld MG. PMID: 25892301.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    8. "Seq-ing" insights into the epigenetics of neuronal gene regulation. Neuron. 2013 Feb 20; 77(4):606-23. Telese F, Gamliel A, Skowronska-Krawczyk D, Garcia-Bassets I, Rosenfeld MG. PMID: 23439116.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    9. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6. Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. PMID: 19234442.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansAnimalsCells
    10. Biomarkers, type II collagen, glucosamine and chondroitin sulfate in osteoarthritis follow-up: the "Magenta osteoarthritis study". J Orthop Traumatol. 2008 Jun; 9(2):81-7. Scarpellini M, Lurati A, Vignati G, Marrazza MG, Telese F, Re K, Bellistri A. PMID: 19384621.
      View in: PubMed   Mentions: 7     Fields:    
    11. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518. Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. PMID: 17289570.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansCells
    12. Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage. J Biol Chem. 2007 Jan 12; 282(2):831-5. Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T. PMID: 17121854.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    13. Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep. 2005 Jan; 6(1):77-82. Telese F, Bruni P, Donizetti A, Gianni D, D'Ambrosio C, Scaloni A, Zambrano N, Rosenfeld MG, Russo T. PMID: 15592452.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    14. Fe65 is not involved in the platelet-derived growth factor-induced processing of Alzheimer's amyloid precursor protein, which activates its caspase-directed cleavage. J Biol Chem. 2004 Apr 16; 279(16):16161-9. Zambrano N, Gianni D, Bruni P, Passaro F, Telese F, Russo T. PMID: 14766758.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
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