Francesca Telese
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Title(s) | Assistant Professor, Medicine |
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School | Health Sciences |
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Address | 9500 Gilman Drive #0648 La Jolla CA 92093
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Phone | 858-246-2607 |
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ORCID
.gif) | 0000-0003-3877-0628  |
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vCard | Download vCard |
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Biography University of Naples Federico II, Italy | Ph.D. | 2007 | Neuroscience |
Overview My lab studies mechanisms of gene regulation involved in neuronal plasticity and behavior in health and disease. We integrate cellular and behavioral studies with transcriptomic and epigenomic measurements at tissue- and cell type-specific level. Currently, we are focusing on the neurobiology of substance use disorders and neuropsychiatric disorders. The identification and manipulation of gene regulatory mechanisms in the brain may enhance our basic understanding of brain function and open the door to new treatments for brain diseases.
Research ORNG Applications Bibliographic
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Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Reelin deficiency contributes to long-term behavioral abnormalities induced by chronic adolescent exposure to Δ9-tetrahydrocannabinol in mice. Neuropharmacology. 2021 Feb 11; 108495.
Iemolo A, Montilla-Perez P, Nguyen J, Risbrough VB, Taffe MA, Telese F. PMID: 33582152.
View in: PubMed Mentions:
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The Cannabinoid Receptor Agonist, WIN, Suppresses the Activation of Proinflammatory Genes Induced by Interleukin 1 Beta in Human Astrocytes. Cannabis and Cannabinoid Research. 2020.
Jerel Adam Fields, Mary K. Swinton, Patricia Montilla-Perez, Eugenia Ricciardelli, and Francesca Telese
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A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain. J Comp Neurol. 2020 Sep 01; 528(13):2218-2238.
Iemolo A, Montilla-Perez P, Lai IC, Meng Y, Nolan S, Wen J, Rusu I, Dulcis D, Telese F. PMID: 32072640.
View in: PubMed Mentions: 1 Fields:
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Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia. Neurobiol Dis. 2019 10; 130:104502.
Swinton MK, Carson A, Telese F, Sanchez AB, Soontornniyomkij B, Rad L, Batki I, Quintanilla B, Pérez-Santiago J, Achim CL, Letendre S, Ellis RJ, Grant I, Murphy AN, Fields JA. PMID: 31238091.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
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Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERa-Regulated Transcriptional Program. Mol Cell. 2017 May 04; 66(3):321-331.e6.
Yang F, Ma Q, Liu Z, Li W, Tan Y, Jin C, Ma W, Hu Y, Shen J, Ohgi KA, Telese F, Liu W, Rosenfeld MG. PMID: 28475868.
View in: PubMed Mentions: 11 Fields: Translation: HumansCells
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Genome-wide epigenetic analysis of MEF2A and MEF2C transcription factors in mouse cortical neurons. Commun Integr Biol. 2015 Nov-Dec; 8(6):e1087624.
Ma Q, Telese F. PMID: 27066173.
View in: PubMed Mentions:
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LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control. Nat Neurosci. 2015 Sep; 18(9):1256-64.
Wang J, Telese F, Tan Y, Li W, Jin C, He X, Basnet H, Ma Q, Merkurjev D, Zhu X, Liu Z, Zhang J, Ohgi K, Taylor H, White RR, Tazearslan C, Suh Y, Macfarlan TS, Pfaff SL, Rosenfeld MG. PMID: 26214369.
View in: PubMed Mentions: 40 Fields: Translation: AnimalsCells
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LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron. 2015 May 06; 86(3):696-710.
Telese F, Ma Q, Perez PM, Notani D, Oh S, Li W, Comoletti D, Ohgi KA, Taylor H, Rosenfeld MG. PMID: 25892301.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimalsCells
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"Seq-ing" insights into the epigenetics of neuronal gene regulation. Neuron. 2013 Feb 20; 77(4):606-23.
PMID: 23439116.
View in: PubMed Mentions: 35 Fields: Translation: HumansCells
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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6.
Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. PMID: 19234442.
View in: PubMed Mentions: 209 Fields: Translation: HumansAnimalsCells
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Biomarkers, type II collagen, glucosamine and chondroitin sulfate in osteoarthritis follow-up: the "Magenta osteoarthritis study". J Orthop Traumatol. 2008 Jun; 9(2):81-7.
Scarpellini M, Lurati A, Vignati G, Marrazza MG, Telese F, Re K, Bellistri A. PMID: 19384621.
View in: PubMed Mentions: 8 Fields:
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Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518.
Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. PMID: 17289570.
View in: PubMed Mentions: 202 Fields: Translation: HumansCells
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Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage. J Biol Chem. 2007 Jan 12; 282(2):831-5.
Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T. PMID: 17121854.
View in: PubMed Mentions: 24 Fields: Translation: AnimalsCells
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Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. . 2005 Jan; 6(1):77-82.
Telese F, Bruni P, Donizetti A, Gianni D, D'Ambrosio C, Scaloni A, Zambrano N, Rosenfeld MG, Russo T. PMID: 15592452.
View in: PubMed Mentions:
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Fe65 is not involved in the platelet-derived growth factor-induced processing of Alzheimer's amyloid precursor protein, which activates its caspase-directed cleavage. J Biol Chem. 2004 Apr 16; 279(16):16161-9.
Zambrano N, Gianni D, Bruni P, Passaro F, Telese F, Russo T. PMID: 14766758.
View in: PubMed Mentions: 10 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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2004 | 1 | 2005 | 1 | 2006 | 1 | 2007 | 1 | 2008 | 1 | 2009 | 1 | 2013 | 1 | 2015 | 3 | 2017 | 1 | 2019 | 1 | 2020 | 2 | 2021 | 1 |
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