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Development of a physiologically-based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady-state conditions. CPT Pharmacometrics Syst Pharmacol. 2024 Dec 23.
Ngo LT, Jung W, Bui TT, Yun HY, Chae JW, Momper JD. PMID: 39714044.
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Interaction of milrinone with extracorporeal life support. J Extra Corpor Technol. 2024 Dec; 56(4):167-173.
Whelan AJ, Mim S, Hunt JP, McKnite AM, Green DJ, Imburgia CE, Momper JD, Stitt G, Watt KM. PMID: 39705580.
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Humans
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Pharmacokinetics and safety of bictegravir in pregnant and postpartum persons with HIV and their infants. J Acquir Immune Defic Syndr. 2024 Nov 21.
Powis KM, Pinilla M, McMorrow F, Stek A, Brooks KM, Shapiro DE, Knowles K, Eke AC, Greene E, Agwu A, Topete L, Browning R, Chakhtoura N, Arora P, Huang X, Best BM, Mirochnick M, Momper JD, IMPAACT 2026 Protocol Team. PMID: 39813286.
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Acute inflammation upregulates FAHFAs in adipose tissue and in differentiated adipocytes. J Biol Chem. 2024 Nov 05; 300(12):107972.
Ertunc ME, Konduri S, Ma Z, Pinto AFM, Donaldson CJ, Momper J, Siegel D, Saghatelian A. PMID: 39510180; PMCID: PMC11647607.
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Evaluation of Effective Half-Life and Its Impact on Time to Steady State for Oral MeltDose Tacrolimus (LCPT) in De Novo Kidney Transplant Recipients. Ther Drug Monit. 2024 Oct 24.
Momper JD, Venkataramanan R, Jantz AS, Cibrik DM, Birdwell K, Nguyen T, Masters BM, Patel SJ. PMID: 39446891.
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Translation:
CTClinical Trials
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Pharmacokinetics and Safety of Remdesivir in Pregnant and Nonpregnant Women With COVID-19: Results From IMPAACT 2032. J Infect Dis. 2024 Oct 16; 230(4):878-888.
Brooks KM, Baltrusaitis K, Clarke DF, Nachman S, Jao J, Purswani MU, Agwu A, Beneri C, Deville JG, Powis KM, Stek AM, Eke AC, Shapiro DE, Capparelli E, Greene E, George K, Yin DE, Jean-Philippe P, Chakhtoura N, Bone F, Bacon K, Johnston B, Reding C, Kersey K, Humeniuk R, Best BM, Mirochnick M, Momper JD, IMPAACT 2032 Study Team
. PMID: 38839047; PMCID: PMC11481345.
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CTClinical Trials
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Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer's Disease Therapeutics. ACS Pharmacol Transl Sci. 2024 Oct 11; 7(10):2924-2935.
Boyarko B, Podvin S, Greenberg B, Arnold S, Juanes AM, van der Kant R, Goldstein L, Momper JD, Bang A, Silverman J, Feldman HH, Hook V. PMID: 39421657; PMCID: PMC11480897.
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In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3. Nutrients. 2024 Jul 12; 16(14).
Falah K, Zhang P, Nigam AK, Maity K, Chang G, Granados JC, Momper JD, Nigam SK. PMID: 39064685; PMCID: PMC11280313.
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PubMed Mentions:
1 Fields:
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HumansAnimals
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A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with early Alzheimer's Disease. Alzheimers Res Ther. 2024 07 05; 16(1):151.
Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas RG, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. PMID: 38970127; PMCID: PMC11225352.
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3 Fields:
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HumansCTClinical Trials
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Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning. Pharmaceutics. 2024 Apr 26; 16(5).
Nigam AK, Momper JD, Ojha AA, Nigam SK. PMID: 38794254; PMCID: PMC11125978.
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A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with Early Alzheimer's Disease. medRxiv. 2024 Mar 22.
Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas R, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. PMID: 38562783; PMCID: PMC10984053.
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Pharmacokinetics, Fecal Output, and Grimace Scores in Rabbits Given Long-acting Buprenorphine or Fentanyl for Postsurgical Analgesia. J Am Assoc Lab Anim Sci. 2024 05 01; 63(3):303-309.
Farkas MR, Dorn S, Muller L, Singh VP, Sepulveda YJ, Suhandynata RT, Momper JD, Masuda K, Richter PJ. PMID: 38490726; PMCID: PMC11193423.
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Animals
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1 Fields:
Translation:
HumansCells
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Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2023 12 01; 94(4):332-336.
Momper JD, Nikanjam M, Best BM, Mirochnick M, Capparelli EV, Cressey TR. PMID: 37884053; PMCID: PMC10686188.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme. Nat Chem Biol. 2023 Nov; 19(11):1406-1414.
Dulchavsky M, Mitra R, Wu K, Li J, Boer K, Liu X, Zhang Z, Vasquez C, Clark CT, Funckes K, Shankar K, Bonnet-Zahedi S, Siddiq M, Sepulveda Y, Suhandynata RT, Momper JD, Calabrese AN, George O, Stull F, Bardwell JCA. PMID: 37770699; PMCID: PMC10611581.
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AnimalsCells
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Cannabidiol Exposure Through Maternal Marijuana Use: Predictions in Breastfed Infants. Clin Pharmacokinet. 2023 11; 62(11):1611-1619.
Yeung CHT, Bertrand KA, Best BM, Capparelli E, Chambers CD, Hajducek DM, Hamadeh A, Ito S, Momper JD, Edginton AN. PMID: 37735347; PMCID: PMC10659070.
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2 Fields:
Translation:
Humans
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Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease. Front Pharmacol. 2023; 14:1190402.
Boyarko B, Podvin S, Greenberg B, Momper JD, Huang Y, Gerwick WH, Bang AG, Quinti L, Griciuc A, Kim DY, Tanzi RE, Feldman HH, Hook V. PMID: 37601062; PMCID: PMC10436590.
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PubMed Mentions:
5
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Severe arsenic poisoning due to Ayurvedic supplements. Clin Case Rep. 2023 Jul; 11(7):e7733.
Hardin J, Seltzer J, Suhandynata R, Spiegel B, Silver R, Thomas D, Galust H, Friedman N, Clark R, Momper J. PMID: 37492071; PMCID: PMC10363841.
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4
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Translating Clinical Pharmacology Data in Pregnancy to Evidence-Based Guideline Recommendations: Perspectives From the HIV Field. J Clin Pharmacol. 2023 06; 63 Suppl 1:S188-S196.
Brooks KM, Scott RK, Best BM, Capparelli E, Momper JD. PMID: 37317495.
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1 Fields:
Translation:
Humans
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Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Cell Chem Biol. 2023 09 21; 30(9):1090-1103.e7.
Hendricks JM, Doubravsky CE, Wehri E, Li Z, Roberts MA, Deol KK, Lange M, Lasheras-Otero I, Momper JD, Dixon SJ, Bersuker K, Schaletzky J, Olzmann JA. PMID: 37178691; PMCID: PMC10524360.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Variable Delta-9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics After Cannabis Smoking in Regular Users. Ther Drug Monit. 2023 10 01; 45(5):689-696.
Liyanage M, Nikanjam M, Capparelli EV, Suhandynata RT, Fitzgerald RL, Marcotte TD, Grant I, Momper JD. PMID: 37199428.
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HumansAnimals
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A single post-exposure oxime RS194B treatment rapidly reactivates acetylcholinesterase and reverses acute symptoms in macaques exposed to diethylphosphorothioate parathion and chlorpyrifos insecticides. J Neurochem. 2024 04; 168(4):370-380.
Rosenberg YJ, Garcia K, Diener J, Sullivan D, Donahue S, Mao L, Lees J, Jiang X, Urban LA, Momper JD, Ho KY, Taylor P. PMID: 36786545.
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1 Fields:
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Animals
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Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors. Chemistry. 2023 Apr 06; 29(20):e202203958.
Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E, Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. PMID: 36617500; PMCID: PMC10894724.
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7 Fields:
Translation:
HumansAnimals
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Comparative Pharmacokinetics and Injection Site Histopathology in Nude Mice Treated with Long-acting Buprenorphine Formulations. J Am Assoc Lab Anim Sci. 2023 03 01; 62(2):147-152.
Illario JA, Osborn KG, Garcia AV, Sepulveda YJ, Momper JD, Kiel JW, Kirihennedige AS, Sun SA, Richter PJ. PMID: 36813268; PMCID: PMC10078935.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Physiologically-based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID-19. CPT Pharmacometrics Syst Pharmacol. 2023 02; 12(2):148-153.
Liu XI, Dallmann A, Brooks K, Best BM, Clarke DF, Mirochnick M, van den Anker JN, Capparelli EV, Momper JD. PMID: 36479969; PMCID: PMC9877749.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota. Pharmacotherapy. 2023 05; 43(5):442-451.
Thomas SP, Denizer E, Zuffa S, Best BM, Bode L, Chambers CD, Dorrestein PC, Liu GY, Momper JD, Nizet V, Tsunoda SM, Tremoulet AH. PMID: 36181712; PMCID: PMC10763576.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Non-invasive skin sampling detects systemically administered drugs in humans. PLoS One. 2022; 17(7):e0271794.
Panitchpakdi M, Weldon KC, Jarmusch AK, Gentry EC, Choi A, Sepulveda Y, Aguirre S, Sun K, Momper JD, Dorrestein PC, Tsunoda SM. PMID: 35881585; PMCID: PMC9321436.
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5 Fields:
Translation:
Humans
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Estimation of Kidney Function in Patients With Multiple Myeloma: Implications for Lenalidomide Dosing. Ann Pharmacother. 2023 01; 57(1):29-35.
Salama E, Lam S, Gonsalves WI, Tzachanis D, Momper JD, M Saunders I. PMID: 35511200; PMCID: PMC9619254.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Pediatric and Adult Placebo Response Rates in Placebo-Controlled Clinical Trials Submitted to the US Food and Drug Administration 2012-2020. J Clin Pharmacol. 2022 08; 62(8):970-982.
Park K, Tran NK, Momper JD, Green DJ, Burckart GJ. PMID: 35118684.
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1 Fields:
Translation:
Humans
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Pharmacokinetics of Atazanavir Boosted With Cobicistat in Pregnant and Postpartum Women With HIV. J Acquir Immune Defic Syndr. 2022 03 01; 89(3):303-309.
Momper JD, Wang J, Stek A, Shapiro DE, Powis KM, Paul ME, Badell ML, Browning R, Chakhtoura N, Denson K, Rungruengthanakit K, George K, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34732682; PMCID: PMC8837686.
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PubMed Mentions:
4 Fields:
Translation:
HumansPHPublic Health
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Optimizing Dolutegravir Initiation in Neonates Using Population Pharmacokinetic Modeling and Simulation. J Acquir Immune Defic Syndr. 2022 01 01; 89(1):108-114.
Piscitelli J, Nikanjam M, Best BM, Acosta E, Mirochnick M, Clarke DF, Capparelli EV, Momper JD. PMID: 34629412; PMCID: PMC8665018.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Brief Report: Pharmacokinetics of Bictegravir and Tenofovir in Combination With Darunavir/Cobicistat in Treatment-Experienced Persons With HIV. J Acquir Immune Defic Syndr. 2021 12 01; 88(4):389-392.
Salama E, Hill L, Patel N, Best BM, Momper JD. PMID: 34285156.
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2 Fields:
Translation:
Humans
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Mechanistic Modeling of Placental Drug Transfer in Humans: How Do Differences in Maternal/Fetal Fraction of Unbound Drug and Placental Influx/Efflux Transfer Rates Affect Fetal Pharmacokinetics? Front Pediatr. 2021; 9:723006.
Liu XI, Green DJ, van den Anker JN, Rakhmanina NY, Ahmadzia HK, Momper JD, Park K, Burckart GJ, Dallmann A. PMID: 34733804; PMCID: PMC8559552.
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PubMed Mentions:
3
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Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development. Front Pediatr. 2021; 9:721059.
Zhao S, Gockenbach M, Grimstein M, Sachs HC, Mirochnick M, Struble K, Belew Y, Wang J, Capparelli EV, Best BM, Johnson T, Momper JD, Maharaj AR. PMID: 34722417; PMCID: PMC8550258.
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PubMed Mentions:
5
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Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients. Microbiol Spectr. 2021 10 31; 9(2):e0046021.
Shoji K, Saito J, Nakagawa H, Funaki T, Fukuda A, Sakamoto S, Kasahara M, Momper JD, Capparelli EV, Miyairi I. PMID: 34612690; PMCID: PMC8510181.
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Humans
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Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021 Oct; 46(5):1459-1464.
Mulligan N, Salama E, Momper JD, Capparelli EV, Stek A, Chakhtoura N, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34254323; PMCID: PMC8448937.
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2 Fields:
Translation:
Humans
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Pharmacokinetics of darunavir and cobicistat in pregnant and postpartum women with HIV. AIDS. 2021 07 01; 35(8):1191-1199.
Momper JD, Wang J, Stek A, Shapiro DE, Scott GB, Paul ME, Febo IL, Burchett S, Smith E, Chakhtoura N, Denson K, Rungruengthanakit K, George K, Yang DZ, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34076612; PMCID: PMC8173003.
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Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis. J Med Chem. 2021 07 08; 64(13):9404-9430.
Klug DM, Mavrogiannaki EM, Forbes KC, Silva L, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, Garcia-Hernández R, Bosch-Navarrete C, Cordón-Obras C, Gómez-Liñán C, Saura A, Momper JD, Martinez-Martinez MS, Manzano P, Syed A, El-Sakkary N, Caffrey CR, Gamarro F, Ruiz-Perez LM, Gonzalez Pacanowska D, Ferrins L, Navarro M, Pollastri MP. PMID: 34156862; PMCID: PMC8412142.
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3 Fields:
Translation:
HumansAnimalsCells
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Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures. J Pharmacol Exp Ther. 2021 Sep; 378(3):315-321.
Shyong YJ, Sepulveda Y, Garcia A, Samskey NM, Radic Z, Sit RK, Sharpless KB, Momper JD, Taylor P. PMID: 34145064; PMCID: PMC11046989.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability. Clin Pharmacokinet. 2021 08; 60(8):971-984.
Tsunoda SM, Gonzales C, Jarmusch AK, Momper JD, Ma JD. PMID: 33959897; PMCID: PMC8332605.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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Cannabidiol reduces withdrawal symptoms in nicotine-dependent rats. Psychopharmacology (Berl). 2021 Aug; 238(8):2201-2211.
Smith LC, Tieu L, Suhandynata RT, Boomhower B, Hoffman M, Sepulveda Y, Carrette LLG, Momper JD, Fitzgerald RL, Hanham K, Dowling J, Kallupi M, George O. PMID: 33909102; PMCID: PMC8295227.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial. Lancet. 2021 04 03; 397(10281):1276-1292.
Lockman S, Brummel SS, Ziemba L, Stranix-Chibanda L, McCarthy K, Coletti A, Jean-Philippe P, Johnston B, Krotje C, Fairlie L, Hoffman RM, Sax PE, Moyo S, Chakhtoura N, Stringer JS, Masheto G, Korutaro V, Cassim H, Mmbaga BT, João E, Hanley S, Purdue L, Holmes LB, Momper JD, Shapiro RL, Thoofer NK, Rooney JF, Frenkel LM, Amico KR, Chinula L, Currier J, IMPAACT 2010/VESTED Study Team and Investigators. PMID: 33812487; PMCID: PMC8132194.
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Pharmacokinetics of tenofovir alafenamide with and without cobicistat in pregnant and postpartum women living with HIV. AIDS. 2021 03 01; 35(3):407-417.
Brooks KM, Momper JD, Pinilla M, Stek AM, Barr E, Weinberg A, Deville JG, Febo IL, Cielo M, George K, Denson K, Rungruengthanakit K, Shapiro DE, Smith E, Chakhtoura N, Rooney JF, Haubrich R, Espina R, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 33252495; PMCID: PMC8238253.
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8 Fields:
Translation:
Humans
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Population Pharmacokinetics of Tenofovir in Pregnant and Postpartum Women Using Tenofovir Disoproxil Fumarate. Antimicrob Agents Chemother. 2021 02 17; 65(3).
Eke AC, Shoji K, Best BM, Momper JD, Stek AM, Cressey TR, Mirochnick M, Capparelli EV. PMID: 33318014; PMCID: PMC8092509.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir. Clin Pharmacokinet. 2021 06; 60(6):795-809.
Liu XI, Momper JD, Rakhmanina NY, Green DJ, Burckart GJ, Cressey TR, Mirochnick M, Best BM, van den Anker JN, Dallmann A. PMID: 33527213; PMCID: PMC9334904.
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8 Fields:
Translation:
Humans
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Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling. Clin Pharmacokinet. 2020 11; 59(11):1433-1450.
Liu XI, Momper JD, Rakhmanina NY, Green DJ, Burckart GJ, Cressey TR, Mirochnick M, Best BM, van den Anker JN, Dallmann A. PMID: 32451908; PMCID: PMC7666002.
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PubMed Mentions:
11 Fields:
Translation:
HumansPHPublic Health
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Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement. Clin Pharmacol Ther. 2021 07; 110(1):36-48.
Eke AC, Olagunju A, Momper J, Penazzato M, Abrams EJ, Best BM, Capparelli EV, Bekker A, Belew Y, Kiser JJ, Struble K, Taylor G, Waitt C, Mirochnick M, Cressey TR, Colbers A, participants of the WHO-IMPAACT workshop on “Approaches to Optimize and Accelerate Pharmacokinetic S. PMID: 32930408; PMCID: PMC8167886.
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14 Fields:
Translation:
HumansPHPublic Health
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Chronopharmacokinetics and Food Effects of Single-Dose LCP-Tacrolimus in Healthy Volunteers. Ther Drug Monit. 2020 10; 42(5):679-685.
Alloway RR, Trofe-Clark J, Brennan DC, Kerr J, Cohen EA, Meier-Kriesche U, Stevens DR, Moten MA, Momper JD. PMID: 32453306.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. J Antimicrob Chemother. 2020 10 01; 75(10):2925-2932.
Probst A, Häberli C, Siegel D, Huang J, Vigneron S, Ta AP, Skinner DE, El-Sakkary N, Momper JD, Gangoiti J, Dong Y, Vennerstrom JL, Charman SA, Caffrey CR, Keiser J. PMID: 32617557; PMCID: PMC7556815.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV. Clin Pharmacokinet. 2020 10; 59(10):1185-1194.
Eke AC, Olagunju A, Best BM, Mirochnick M, Momper JD, Abrams E, Penazzato M, Cressey TR, Colbers A. PMID: 32757103; PMCID: PMC7550310.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Ethical Considerations for Pediatric Placebo-Controlled Trials: FDA Outcomes and Perspectives. Ther Innov Regul Sci. 2021 03; 55(2):282-303.
Momper JD, Green DJ, Park K, Burckart GJ, Snyder DL. PMID: 32901443.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol. Reprod Health. 2020 Aug 24; 17(1):128.
Cafferata ML, Toscani MA, Althabe F, Belizán JM, Bergel E, Berrueta M, Capparelli EV, Ciganda Á, Danesi E, Dumonteil E, Gibbons L, Gulayin PE, Herrera C, Momper JD, Rossi S, Shaffer JG, Schijman AG, Sosa-Estani S, Stella CB, Klein K, Buekens P. PMID: 32831069; PMCID: PMC7446054.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Pharmacokinetic Enhancement of HIV Antiretroviral Therapy During Pregnancy. J Clin Pharmacol. 2020 12; 60(12):1537-1550.
Salama E, Eke AC, Best BM, Mirochnick M, Momper JD. PMID: 32798276; PMCID: PMC8227837.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. Clin Transl Sci. 2020 09; 13(5):972-984.
Jarmusch AK, Vrbanac A, Momper JD, Ma JD, Alhaja M, Liyanage M, Knight R, Dorrestein PC, Tsunoda SM. PMID: 32216086; PMCID: PMC7485946.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology. Clin Pharmacol Ther. 2020 07; 108(1):40-53.
Nigam SK, Bush KT, Bhatnagar V, Poloyac SM, Momper JD. PMID: 32119114; PMCID: PMC7292762.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats. Psychopharmacology (Berl). 2020 May; 237(5):1545-1555.
Kimbrough A, Kononoff J, Simpson S, Kallupi M, Sedighim S, Palomino K, Conlisk D, Momper JD, de Guglielmo G, George O. PMID: 32114633; PMCID: PMC7269712.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Clinical lactation studies and the role of pharmacokinetic modeling and simulation in predicting drug exposures in breastfed infants. J Pharmacokinet Pharmacodyn. 2020 08; 47(4):295-304.
Anderson PO, Momper JD. PMID: 32034606.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Extrapolation of Adult Efficacy to Pediatric Patients With Chemotherapy-Induced Nausea and Vomiting. J Clin Pharmacol. 2020 06; 60(6):775-784.
Momper JD, Heinrichs MT, Krudys K, Griebel D, Kumar S, Kim I, Mehrotra N, Mulberg AE, Garimella N, Nelson R, Reaman G, Sinha V, Yao L, Zineh I, Burckart G, Sachs H, Mulugeta Y. PMID: 31967340.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Use of Simulation Strategies to Predict Subtherapeutic Meropenem Exposure Caused by Augmented Renal Clearance in Critically Ill Pediatric Patients With Sepsis. J Pediatr Pharmacol Ther. 2020; 25(5):413-422.
Avedissian SN, Skochko SM, Le J, Hingtgen S, Harvey H, Capparelli EV, Richardson A, Momper J, Mak RH, Neely M, Bradley JS. PMID: 32641911; PMCID: PMC7337137.
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PubMed Mentions:
11
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Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir. J Clin Pharmacol. 2020 02; 60(2):240-255.
Liu XI, Momper JD, Rakhmanina N, van den Anker JN, Green DJ, Burckart GJ, Best BM, Mirochnick M, Capparelli EV, Dallmann A. PMID: 31489678; PMCID: PMC7316130.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin. J Am Chem Soc. 2019 07 31; 141(30):11765-11769.
Callmann CE, LeGuyader CLM, Burton ST, Thompson MP, Hennis R, Barback C, Henriksen NM, Chan WC, Jaremko MJ, Yang J, Garcia A, Burkart MD, Gilson MK, Momper JD, Bertin PA, Gianneschi NC. PMID: 31317744; PMCID: PMC6676409.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Determination of Benznidazole in Human Dried Blood Spots by Liquid Chromatography-Mass Spectrometry to Monitor Adherence to Trypanosoma cruzi Infection Treatment in Infants and Children. Am J Trop Med Hyg. 2019 07; 101(1):116-122.
Momper JD, Hanan NJ, Rossi SS, Mirochnick MH, Cafferata ML, Lavenia A, Flores I, Gibbons L, Ciganda A, Sosa Estani S, Capparelli EV, Buekens P. PMID: 31115303; PMCID: PMC6609196.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Interaction Between Cyclosporine and Palbociclib in a Renal Transplant Patient: Case Report and Pharmacokinetic Perspective. J Pharm Pract. 2020 Dec; 33(6):912-914.
Momper JD, Yang J, Kerr J, Saunders I, Smith J, Shah MM. PMID: 31248333.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure. Chem Biol Interact. 2019 Aug 01; 308:194-197.
Taylor P, Yan-Jye S, Momper J, Hou W, Camacho-Hernandez GA, Radic' Z, Rosenberg Y, Kovarik Z, Sit R, Sharpless KB. PMID: 31100277.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation. Clin J Am Soc Nephrol. 2019 04 05; 14(4):540-548.
Momper JD, Yang J, Gockenbach M, Vaida F, Nigam SK. PMID: 30885911; PMCID: PMC6450358.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. J Med Chem. 2019 02 14; 62(3):1609-1625.
Perez C, Barkley-Levenson AM, Dick BL, Glatt PF, Martinez Y, Siegel D, Momper JD, Palmer AA, Cohen SM. PMID: 30628789; PMCID: PMC6467756.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development. J Med Chem. 2019 01 24; 62(2):665-687.
Bachovchin KA, Sharma A, Bag S, Klug DM, Schneider KM, Singh B, Jalani HB, Buskes MJ, Mehta N, Tanghe S, Momper JD, Sciotti RJ, Rodriguez A, Mensa-Wilmot K, Pollastri MP, Ferrins L. PMID: 30565932; PMCID: PMC6556231.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Elvitegravir/cobicistat pharmacokinetics in pregnant and postpartum women with HIV. AIDS. 2018 11 13; 32(17):2507-2516.
Momper JD, Best BM, Wang J, Capparelli EV, Stek A, Barr E, Badell ML, Acosta EP, Purswani M, Smith E, Chakhtoura N, Park K, Burchett S, Shapiro DE, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 30134297; PMCID: PMC6209536.
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PubMed Mentions:
26 Fields:
Translation:
HumansCTClinical Trials
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Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors. J Am Chem Soc. 2018 09 12; 140(36):11424-11437.
Yoo E, Stokes BH, de Jong H, Vanaerschot M, Kumar T, Lawrence N, Njoroge M, Garcia A, Van der Westhuyzen R, Momper JD, Ng CL, Fidock DA, Bogyo M. PMID: 30107725; PMCID: PMC6407133.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Author Correction: Blocking Zika virus vertical transmission. Sci Rep. 2018 Jun 05; 8(1):8794.
Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29867187; PMCID: PMC5986756.
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3 Fields:
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Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication. Expert Opin Drug Metab Toxicol. 2018 Jun; 14(6):561-570.
Momper JD, Nigam SK. PMID: 29746174; PMCID: PMC6277044.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Blocking Zika virus vertical transmission. Sci Rep. 2018 01 19; 8(1):1218.
Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. PMID: 29352135; PMCID: PMC5775359.
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25 Fields:
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Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques. Toxicol Lett. 2018 Sep 01; 293:229-234.
Rosenberg YJ, Wang J, Ooms T, Rajendran N, Mao L, Jiang X, Lees J, Urban L, Momper JD, Sepulveda Y, Shyong YJ, Taylor P. PMID: 29129799; PMCID: PMC5943181.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsPHPublic Health
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Evaluation of the effect of torsemide on warfarin dosage requirements. Int J Clin Pharm. 2017 Aug; 39(4):831-835.
Lai S, Momper JD, Yam FK. PMID: 28523460.
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Translation:
Humans
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Sex differences in transplantation. Transplant Rev (Orlando). 2017 07; 31(3):145-150.
Momper JD, Misel ML, McKay DB. PMID: 28262425; PMCID: PMC5795092.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams. Antimicrob Agents Chemother. 2016 09; 60(9):5539-45.
Momper JD, Capparelli EV, Wade KC, Kantak A, Dhanireddy R, Cummings JJ, Nedrelow JH, Hudak ML, Mundakel GT, Natarajan G, Gao J, Laughon M, Smith PB, Benjamin DK. PMID: 27401564; PMCID: PMC4997840.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Evaluation of Proposed In Vivo Probe Substrates and Inhibitors for Phenotyping Transporter Activity in Humans. J Clin Pharmacol. 2016 07; 56 Suppl 7:S82-98.
Momper JD, Tsunoda SM, Ma JD. PMID: 27385182.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models. J Pediatr Pharmacol Ther. 2016 May-Jun; 21(3):224-32.
Marek E, Momper JD, Hines RN, Takao CM, Gill JC, Pravica V, Gaedigk A, Burckart GJ, Neville KA. PMID: 27453700; PMCID: PMC4956330.
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PubMed Mentions:
4
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Failed Pediatric Drug Development Trials. Clin Pharmacol Ther. 2015 Sep; 98(3):245-51.
Momper JD, Mulugeta Y, Burckart GJ. PMID: 25963725.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Pediatric drug development programs for type 2 diabetes: A review. J Clin Pharmacol. 2015 Jul; 55(7):731-8.
Christensen ML, Franklin BE, Momper JD, Reed MD. PMID: 25781151.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Adverse Event Detection and Labeling in Pediatric Drug Development: Antiretroviral Drugs. Ther Innov Regul Sci. 2015 Mar; 49(2):302-309.
Momper JD, Chang Y, Jackson M, Schuette P, Seo S, Younis I, Abernethy DR, Yao L, Capparelli EV, Burckart GJ. PMID: 30222418.
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PubMed Mentions:
4 Fields:
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Consensus recommendations for systematic evaluation of drug-drug interaction evidence for clinical decision support. Drug Saf. 2015 Feb; 38(2):197-206.
Scheife RT, Hines LE, Boyce RD, Chung SP, Momper JD, Sommer CD, Abernethy DR, Horn JR, Sklar SJ, Wong SK, Jones G, Brown ML, Grizzle AJ, Comes S, Wilkins TL, Borst C, Wittie MA, Malone DC. PMID: 25556085; PMCID: PMC4624322.
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PubMed Mentions:
62 Fields:
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Drug development for pediatric neurogenic bladder dysfunction: dosing, endpoints, and study design. J Clin Pharmacol. 2014 Nov; 54(11):1239-46.
Momper JD, Karesh A, Green DJ, Hirsch M, Khurana M, Lee J, Kim MJ, Mulugeta Y, Sachs HC, Yao L, Burckart GJ. PMID: 24922179.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Therapeutic drug monitoring as a component of personalized medicine: applications in pediatric drug development. Clin Pharmacol Ther. 2014 Feb; 95(2):138-40.
Momper JD, Wagner JA. PMID: 24253660.
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6 Fields:
Translation:
Humans
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Adolescent dosing and labeling since the Food and Drug Administration Amendments Act of 2007. JAMA Pediatr. 2013 Oct; 167(10):926-32.
Momper JD, Mulugeta Y, Green DJ, Karesh A, Krudys KM, Sachs HC, Yao LP, Burckart GJ. PMID: 23921678.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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The integration of allometry and virtual populations to predict clearance and clearance variability in pediatric populations over the age of 6 years. Clin Pharmacokinet. 2013 Aug; 52(8):693-703.
Edginton AN, Shah B, Sevestre M, Momper JD. PMID: 23588537.
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16 Fields:
Translation:
Humans
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Genetics-based pediatric warfarin dosage regimen derived using pharmacometric bridging. J Pediatr Pharmacol Ther. 2013 Jul; 18(3):209-19.
Lala M, Burckart GJ, Takao CM, Pravica V, Momper JD, Gobburu JV. PMID: 24052784; PMCID: PMC3775555.
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PubMed Mentions:
11
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Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection. Transpl Infect Dis. 2013 Feb; 15(1):34-41.
Momper JD, Zhao Y, Shapiro R, Schonder KS, Gao Y, Randhawa PS, Venkataramanan R. PMID: 23025519; PMCID: PMC3654813.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The impact of conversion from prograf to generic tacrolimus in liver and kidney transplant recipients with stable graft function. Am J Transplant. 2011 Sep; 11(9):1861-7.
Momper JD, Ridenour TA, Schonder KS, Shapiro R, Humar A, Venkataramanan R. PMID: 21714845.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Nonrenal drug clearance in CKD: Searching for the path less traveled. Adv Chronic Kidney Dis. 2010 Sep; 17(5):384-91.
Momper JD, Venkataramanan R, Nolin TD. PMID: 20727508.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Determination of cidofovir in human plasma after low dose drug administration using high-performance liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2010 Dec 01; 53(4):1015-21.
Momper JD, Zhang S, Randhawa PS, Shapiro R, Schonder KS, Venkataramanan R. PMID: 20673618; PMCID: PMC3654809.
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PubMed Mentions:
3 Fields:
Translation:
Humans