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Shigeki Miyamoto

Photo of Shigeki Miyamoto
Title(s)Adjunct Professor, Pharmacology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
Emailsmiyamoto@ucsd.edu
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    Collapse Biography 
    Collapse education and training
    University of TokyoPh.D.

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    Cardiomyocyte CaM kinase II as a driver of cardiac inflammation and remodeling
    NIH R01HL145459Dec 15, 2018 - Nov 30, 2022
    Role: Co-Principal Investigator
    Hexokinase-II protects the heart against ischemia through regulation of autophagy
    NIH R56HL097037Sep 4, 2015 - Aug 31, 2018
    Role: Principal Investigator
    Mitochondrial Protection by Hexokinase-II and Akt in the Heart
    NIH R01HL097037Aug 1, 2009 - Apr 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cardiomyocyte YAP represses myocardial inflammation and fibrosis and restrains MEF2-regulated gene expression. Am J Physiol Heart Circ Physiol. 2025 Sep 01; 329(3):H774-H787. Ninh VK, Barlow M, Aydin S, Brand CS, Yu J, Smith J, Francisco J, Daneman R, King KR, Miyamoto S, Del Re DP, Brown JH. PMID: 40637445; PMCID: PMC12338972.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    2. NEMO is essential for directing the kinases IKKα and ATM to the sites of DNA damage. Sci Signal. 2025 Mar 11; 18(877):eadr0128. Alonso-Marañón J, Solé L, Álvarez-Villanueva D, Maqueda M, Lobo-Jarne T, Montoto Á, Yélamos J, Borràs E, Uraga L, Hooper C, Sabidó E, Miyamoto S, Bigas A, Espinosa L. PMID: 40067909; PMCID: PMC12070652.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Untangling the role of RhoA in the heart: protective effect and mechanism. Cell Death Dis. 2024 Aug 09; 15(8):579. Miyamoto S. PMID: 39122698; PMCID: PMC11315981.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    4. Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion. Sci Rep. 2023 12 16; 13(1):22412. Chaim OM, Miki S, Prager BC, Ma J, Jeong AY, Lara J, Tran NK, Smith JM, Rich JN, Gutkind JS, Miyamoto S, Furnari FB, Brown JH. PMID: 38104152; PMCID: PMC10725435.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice. J Clin Invest. 2023 12 15; 133(24). Rajagopalan A, Feng Y, Gayatri MB, Ranheim EA, Klungness T, Matson DR, Lee MH, Jung MM, Zhou Y, Gao X, Nadiminti KV, Yang DT, Tran VL, Padron E, Miyamoto S, Bresnick EH, Zhang J. PMID: 37847561; PMCID: PMC10721149.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    6. Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression. Microbiol Spectr. 2023 08 17; 11(4):e0142123. Romero N, Tishchenko A, Verhamme R, Wuerzberger-Davis SM, Van Waesberghe C, Nauwynck HJ, Miyamoto S, Favoreel HW. PMID: 37466427; PMCID: PMC10434116.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes. Front Immunol. 2023; 14:1103231. Torres A, Kang S, Mahony CB, Cedeño M, Oliveira PG, Fernandez-Bustamante M, Kemble S, Laragione T, Gulko PS, Croft AP, Sanchez-Lopez E, Miyamoto S, Guma M. PMID: 37529037; PMCID: PMC10389265.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    8. Hippo signaling pathway and mitochondrial dysfunction in Takotsubo syndrome. Am J Physiol Heart Circ Physiol. 2023 04 01; 324(4):H525-H527. Miyamoto S. PMID: 36800511.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    9. Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma. Life Sci Alliance. 2023 03; 6(3). De Bakshi D, Chen YC, Wuerzberger-Davis SM, Ma M, Waters BJ, Li L, Suzuki A, Miyamoto S. PMID: 36625202; PMCID: PMC9748848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells. Oncogenesis. 2022 Oct 25; 11(1):65. Lee MH, Sung K, Beebe D, Huang W, Shapiro D, Miyamoto S, Abel EJ. PMID: 36284084; PMCID: PMC9596416.
      View in: PubMed   Mentions: 6  
    11. RHOA, a small G-protein, signals to mitophagy through regulation of PINK1 protein stability and protects cardiomyocytes against ischemia. Autophagy. 2023 06; 19(6):1865-1866. Tu M, Miyamoto S. PMID: 36201460; PMCID: PMC10262781.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. Mol Cancer Res. 2022 09 02; 20(9):1456-1466. Mark C, Warrick J, Callander NS, Hematti P, Miyamoto S. PMID: 35604822; PMCID: PMC9444915.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria. Cell Death Differ. 2022 12; 29(12):2472-2486. Tu M, Tan VP, Yu JD, Tripathi R, Bigham Z, Barlow M, Smith JM, Brown JH, Miyamoto S. PMID: 35760846; PMCID: PMC9751115.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    14. Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution. Integr Biol (Camb). 2022 06 08; 14(3):49-61. Mark C, Callander NS, Chng K, Miyamoto S, Warrick J. PMID: 35653717; PMCID: PMC9175638.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Splicing and Dicing: A Deeper Dive Into CaMKIIδ and Cardiac Inflammation. Circ Res. 2022 03 18; 130(6):904-906. Brown JH, Miyamoto S. PMID: 35298299; PMCID: PMC8944245.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger. Cells. 2021 11 27; 10(12). Yu JD, Miyamoto S. PMID: 34943839; PMCID: PMC8699551.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ. Int J Mol Sci. 2021 Apr 23; 22(9). Pavez-Giani MG, Sánchez-Aguilera PI, Bomer N, Miyamoto S, Booij HG, Giraldo P, Oberdorf-Maass SU, Nijholt KT, Yurista SR, Milting H, van der Meer P, Boer RA, Heller Brown J, Sillje HWH, Westenbrink BD. PMID: 33922643; PMCID: PMC8122940.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    18. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, et al. PMID: 33634751; PMCID: PMC7996087.
      View in: PubMed   Mentions: 1317     Fields:    Translation:HumansAnimalsCells
    19. SiglecF(HI) Marks Late-Stage Neutrophils of the Infarcted Heart: A Single-Cell Transcriptomic Analysis of Neutrophil Diversification. J Am Heart Assoc. 2021 02 16; 10(4):e019019. Calcagno DM, Zhang C, Toomu A, Huang K, Ninh VK, Miyamoto S, Aguirre AD, Fu Z, Heller Brown J, King KR. PMID: 33525909; PMCID: PMC7955351.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    20. Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling. PLoS Biol. 2020 09; 18(9):e3000866. Zhang JZ, Nguyen AH, Miyamoto S, Heller Brown J, McCulloch AD, Zhang J. PMID: 32881857; PMCID: PMC7494096.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    21. IκBα Nuclear Export Enables 4-1BB-Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity. J Immunol. 2020 09 15; 205(6):1540-1553. Lisiero DN, Cheng Z, Tejera MM, Neldner BT, Warrick JW, Wuerzberger-Davis SM, Hoffmann A, Suresh M, Miyamoto S. PMID: 32817348; PMCID: PMC7484350.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    22. IκBα deficiency imposes a fetal phenotype to intestinal stem cells. EMBO Rep. 2020 06 04; 21(6):e49708. Marruecos L, Bertran J, Guillén Y, González J, Batlle R, López-Arribillaga E, Garrido M, Ruiz-Herguido C, Lisiero D, González-Farré M, Arce-Gallego S, Iglesias M, Nebreda AR, Miyamoto S, Bigas A, Espinosa L. PMID: 32270911; PMCID: PMC7271649.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    23. Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia. Cell Death Dis. 2019 09 30; 10(10):730. Tan VP, Smith JM, Tu M, Yu JD, Ding EY, Miyamoto S. PMID: 31570704; PMCID: PMC6768853.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    24. Inflammation in nonischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling. Am J Physiol Heart Circ Physiol. 2019 11 01; 317(5):H877-H890. Suetomi T, Miyamoto S, Brown JH. PMID: 31441689; PMCID: PMC6879920.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    25. Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. Front Immunol. 2019; 10:1743. de Oliveira PG, Farinon M, Sanchez-Lopez E, Miyamoto S, Guma M. PMID: 31428089; PMCID: PMC6688519.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    26. Autophagy and cardiac aging. Cell Death Differ. 2019 03; 26(4):653-664. Miyamoto S. PMID: 30692640; PMCID: PMC6460392.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    27. Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload. J Biol Chem. 2019 03 08; 294(10):3603-3617. Byun J, Del Re DP, Zhai P, Ikeda S, Shirakabe A, Mizushima W, Miyamoto S, Brown JH, Sadoshima J. PMID: 30635403; PMCID: PMC6416448.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    28. Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling. Circulation. 2018 11 27; 138(22):2530-2544. Suetomi T, Willeford A, Brand CS, Cho Y, Ross RS, Miyamoto S, Brown JH. PMID: 30571348; PMCID: PMC6309790.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
    29. Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Ann Rheum Dis. 2018 11; 77(11):1636-1643. Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M. PMID: 30061164; PMCID: PMC6328432.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    30. RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes. Cell Signal. 2018 Oct; 50:48-57. Brand CS, Tan VP, Brown JH, Miyamoto S. PMID: 29953931; PMCID: PMC6361616.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    31. CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis. JCI Insight. 2018 06 21; 3(12). Willeford A, Suetomi T, Nickle A, Hoffman HM, Miyamoto S, Heller Brown J. PMID: 29925681; PMCID: PMC6124412.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    32. YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity. Oncogene. 2018 10; 37(41):5492-5507. Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. PMID: 29887596; PMCID: PMC6195840.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    33. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma. J Biol Chem. 2018 02 16; 293(7):2452-2465. Huynh M, Pak C, Markovina S, Callander NS, Chng KS, Wuerzberger-Davis SM, Bakshi DD, Kink JA, Hematti P, Hope C, Asimakopoulos F, Rui L, Miyamoto S. PMID: 29279332; PMCID: PMC5818187.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    34. Mitophagy as a Protective Mechanism against Myocardial Stress. Compr Physiol. 2017 Sep 12; 7(4):1407-1424. Nah J, Miyamoto S, Sadoshima J. PMID: 28915329.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    35. [Hexokinase 2 mediated cellular protection: interaction with Akt/mTORC1 to regulate mitochondrial protection and autophagy]. Seikagaku. 2017 Apr; 89(2):199-210. Miyamoto S. PMID: 29624985.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    36. PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells. Cell Death Discov. 2017; 3:16103. Xiong X, Wen YA, Mitov MI, C Oaks M, Miyamoto S, Gao T. PMID: 28179998; PMCID: PMC5253420.
      View in: PubMed   Mentions: 21  
    37. CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α. J Mol Cell Cardiol. 2017 02; 103:48-55. Gray CB, Suetomi T, Xiang S, Mishra S, Blackwood EA, Glembotski CC, Miyamoto S, Westenbrink BD, Brown JH. PMID: 28077321; PMCID: PMC5564300.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    38. Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection. J Mol Cell Cardiol. 2017 02; 103:1-10. Yung BS, Brand CS, Xiang SY, Gray CB, Means CK, Rosen H, Chun J, Purcell NH, Brown JH, Miyamoto S. PMID: 28017639; PMCID: PMC5410967.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    39. Immunoregulatory roles of versican proteolysis in the myeloma microenvironment. Blood. 2016 08 04; 128(5):680-5. Hope C, Foulcer S, Jagodinsky J, Chen SX, Jensen JL, Patel S, Leith C, Maroulakou I, Callander N, Miyamoto S, Hematti P, Apte SS, Asimakopoulos F. PMID: 27259980; PMCID: PMC4974200.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    40. Drp1 and Mitochondrial Autophagy Lend a Helping Hand in Adaptation to Pressure Overload. Circulation. 2016 Mar 29; 133(13):1225-7. Miyamoto S, Brown JH. PMID: 26915632; PMCID: PMC4811683.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    41. Evaluating mitochondrial autophagy in the mouse heart. J Mol Cell Cardiol. 2016 Mar; 92:134-9. Shirakabe A, Fritzky L, Saito T, Zhai P, Miyamoto S, Gustafsson ÅB, Kitsis RN, Sadoshima J. PMID: 26868976.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    42. Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals. J Mol Cell Cardiol. 2016 06; 95:31-41. Tan VP, Miyamoto S. PMID: 26773603; PMCID: PMC4909545.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    43. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
      View in: PubMed   Mentions: 3002     Fields:    Translation:HumansAnimals
    44. Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation. Mol Cell Biol. 2016 Jan 01; 36(1):39-49. Yu OM, Miyamoto S, Brown JH. PMID: 26459764; PMCID: PMC4702594.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    45. Strategies from UW-Madison for rescuing biomedical research in the US. Elife. 2015 Jun 30; 4:e09305. Kimble J, Bement WM, Chang Q, Cox BL, Drinkwater NR, Gourse RL, Hoskins AA, Huttenlocher A, Kreeger PK, Lambert PF, Mailick MR, Miyamoto S, Moss RL, O'Connor-Giles KM, Roopra A, Saha K, Seidel HS. PMID: 26122792; PMCID: PMC4484056.
      View in: PubMed   Mentions: 20     Fields:    
    46. IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. J Biol Chem. 2015 Jul 17; 290(29):17967-17984. Hwang B, McCool K, Wan J, Wuerzberger-Davis SM, Young EWK, Choi EY, Cingolani G, Weaver BA, Miyamoto S. PMID: 26060253; PMCID: PMC4505044.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    47. Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma. Cancer Immunol Res. 2015 Aug; 3(8):881-90. Jensen JL, Rakhmilevich A, Heninger E, Broman AT, Hope C, Phan F, Miyamoto S, Maroulakou I, Callander N, Hematti P, Chesi M, Bergsagel PL, Sondel P, Asimakopoulos F. PMID: 25941352; PMCID: PMC4527950.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    48. Cellular redox status determines sensitivity to BNIP3-mediated cell death in cardiac myocytes. Am J Physiol Cell Physiol. 2015 Jun 15; 308(12):C983-92. Lee Y, Kubli DA, Hanna RA, Cortez MQ, Lee HY, Miyamoto S, Gustafsson ÅB. PMID: 25810259; PMCID: PMC4469750.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    49. Quantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stress. PLoS One. 2015; 10(3):e0116374. Hwang B, Phan FP, McCool K, Choi EY, You J, Johnson A, Audhya A, Miyamoto S. PMID: 25742655; PMCID: PMC4350935.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    50. Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation. Circ Res. 2015 Feb 27; 116(5):e28-39. Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy AN, Miyamoto S, Dorn GW, Heller Brown J. PMID: 25605649; PMCID: PMC4344921.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    51. HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection. Autophagy. 2015; 11(6):963-4. Tan VP, Miyamoto S. PMID: 26075878; PMCID: PMC4502787.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    52. Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling. Exp Cell Res. 2015 Feb 01; 331(1):58-72. Jackson SS, Oberley C, Hooper CP, Grindle K, Wuerzberger-Davis S, Wolff J, McCool K, Rui L, Miyamoto S. PMID: 25304104; PMCID: PMC4302062.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    53. Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1205-13. Edwards AG, Grandi E, Hake JE, Patel S, Li P, Miyamoto S, Omens JH, Heller Brown J, Bers DM, McCulloch AD. PMID: 25236710; PMCID: PMC4301603.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    54. Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. J Mol Cell Cardiol. 2014 Oct; 75:152-61. Zhao X, Ding EY, Yu OM, Xiang SY, Tan-Sah VP, Yung BS, Hedgpeth J, Neubig RR, Lau LF, Brown JH, Miyamoto S. PMID: 25106095; PMCID: PMC4157956.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    55. DEAD-box helicase DP103 defines metastatic potential of human breast cancers. J Clin Invest. 2014 Sep; 124(9):3807-24. Shin EM, Hay HS, Lee MH, Goh JN, Tan TZ, Sen YP, Lim SW, Yousef EM, Ong HT, Thike AA, Kong X, Wu Z, Mendoz E, Sun W, Salto-Tellez M, Lim CT, Lobie PE, Lim YP, Yap CT, Zeng Q, Sethi G, Lee MB, Tan P, Goh BC, Miller LD, Thiery JP, Zhu T, Gaboury L, Tan PH, Hui KM, Yip GW, Miyamoto S, Kumar AP, Tergaonkar V. PMID: 25083991; PMCID: PMC4151228.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    56. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation. PLoS One. 2014; 9(2):e88052. Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF. PMID: 24558376; PMCID: PMC3928145.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    57. Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition. Mol Cell. 2014 Feb 20; 53(4):521-33. Roberts DJ, Tan-Sah VP, Ding EY, Smith JM, Miyamoto S. PMID: 24462113; PMCID: PMC3943874.
      View in: PubMed   Mentions: 181     Fields:    Translation:AnimalsCells
    58. PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart. Sci Signal. 2013 Dec 17; 6(306):ra108. Xiang SY, Ouyang K, Yung BS, Miyamoto S, Smrcka AV, Chen J, Heller Brown J. PMID: 24345679; PMCID: PMC4035240.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    59. Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes. J Biol Chem. 2013 Aug 16; 288(33):23798-806. Roberts DJ, Tan-Sah VP, Smith JM, Miyamoto S. PMID: 23836898; PMCID: PMC3745326.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    60. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013 Jun 15; 27(12):1365-77. Thomas RL, Roberts DJ, Kubli DA, Lee Y, Quinsay MN, Owens JB, Fischer KM, Sussman MA, Miyamoto S, Gustafsson ÅB. PMID: 23788623; PMCID: PMC3701192.
      View in: PubMed   Mentions: 147     Fields:    Translation:AnimalsCells
    61. Conference report from the 2012 AHA scientific sessions in Los Angeles. Expert Opin Ther Targets. 2013 Jun; 17(6):733-7. Westenbrink BD, Edwards AG, Miyamoto S. PMID: 23642039.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    62. Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes. Circ Res. 2011 Dec 09; 109(12):1354-62. Mishra S, Gray CB, Miyamoto S, Bers DM, Brown JH. PMID: 21998325; PMCID: PMC3241507.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    63. NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress. Mol Cell. 2011 Jul 22; 43(2):180-91. Lee MH, Mabb AM, Gill GB, Yeh ET, Miyamoto S. PMID: 21777808; PMCID: PMC3172129.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    64. RhoA protects the mouse heart against ischemia/reperfusion injury. J Clin Invest. 2011 Aug; 121(8):3269-76. Xiang SY, Vanhoutte D, Del Re DP, Purcell NH, Ling H, Banerjee I, Bossuyt J, Lang RA, Zheng Y, Matkovich SJ, Miyamoto S, Molkentin JD, Dorn GW, Brown JH. PMID: 21747165; PMCID: PMC3148727.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    65. A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Mol Cell Biol. 2011 Jul; 31(14):2774-86. Yang Y, Xia F, Hermance N, Mabb A, Simonson S, Morrissey S, Gandhi P, Munson M, Miyamoto S, Kelliher MA. PMID: 21606198; PMCID: PMC3133388.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    66. IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS One. 2011 Apr 07; 6(4):e18447. Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, Hauer-Jensen M, Miyamoto S, Zhou D. PMID: 21490922; PMCID: PMC3072401.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    67. ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Mol Cell. 2010 Oct 08; 40(1):75-86. Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, Miyamoto S, Tergaonkar V. PMID: 20932476; PMCID: PMC3048026.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    68. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest. 2010 Aug; 120(8):2805-16. Zhang D, Contu R, Latronico MV, Zhang J, Zhang JL, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, Chen J, Sonenberg N, Condorelli G. PMID: 20644257; PMCID: PMC2912201.
      View in: PubMed   Mentions: 206     Fields:    Translation:AnimalsCells
    69. PHLPP-1 negatively regulates Akt activity and survival in the heart. Circ Res. 2010 Aug 20; 107(4):476-84. Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. PMID: 20576936; PMCID: PMC2957297.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    70. Revisited and revised: is RhoA always a villain in cardiac pathophysiology? J Cardiovasc Transl Res. 2010 Aug; 3(4):330-43. Miyamoto S, Del Re DP, Xiang SY, Zhao X, Florholmen G, Brown JH. PMID: 20559774; PMCID: PMC3005405.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    71. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ Res. 2010 Apr 16; 106(7):1265-74. Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, Gustafsson AB, Miyamoto S, Glembotski CC, Gottlieb RA, Brown JH, Sussman MA. PMID: 20203306; PMCID: PMC2864233.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    72. TAK-ling IKK activation: "Ub" the judge. Sci Signal. 2010 Jan 19; 3(105):pe3. Wuerzberger-Davis SM, Miyamoto S. PMID: 20086238.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    73. A PAR-SUMOnious mechanism of NEMO activation. Mol Cell. 2009 Nov 13; 36(3):349-50. McCool K, Miyamoto S. PMID: 19917242.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    74. Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue. J Bioenerg Biomembr. 2009 Apr; 41(2):169-80. Miyamoto S, Murphy AN, Brown JH. PMID: 19377835; PMCID: PMC2732429.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    75. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovasc Res. 2009 May 01; 82(2):272-85. Miyamoto S, Rubio M, Sussman MA. PMID: 19279164; PMCID: PMC2675933.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    76. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. J Mol Cell Cardiol. 2009 Jul; 47(1):96-103. Rubio M, Avitabile D, Fischer K, Emmanuel G, Gude N, Miyamoto S, Mishra S, Schaefer EM, Brown JH, Sussman MA. PMID: 19269295; PMCID: PMC2692628.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    77. Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection. J Biol Chem. 2008 Dec 19; 283(51):35622-9. Del Re DP, Miyamoto S, Brown JH. PMID: 18854312; PMCID: PMC2602897.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    78. Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress. EMBO J. 2008 Jul 23; 27(14):1963-73. Wu ZH, Miyamoto S. PMID: 18583959; PMCID: PMC2486281.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    79. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. PLoS One. 2008 Jun 18; 3(6):e2446. Hensler ME, Miyamoto S, Nizet V. PMID: 18560574; PMCID: PMC2409074.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    80. Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo. J Immunol. 2008 Jun 01; 180(11):7107-11. Ni CY, Wu ZH, Florence WC, Parekh VV, Arrate MP, Pierce S, Schweitzer B, Van Kaer L, Joyce S, Miyamoto S, Ballard DW, Oltz EM. PMID: 18490708; PMCID: PMC2601684.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    81. S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses. J Biol Chem. 2008 May 02; 283(18):11954-63. Means CK, Miyamoto S, Chun J, Brown JH. PMID: 18296752; PMCID: PMC2335351.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    82. RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. J Biol Chem. 2007 Mar 16; 282(11):8069-78. Del Re DP, Miyamoto S, Brown JH. PMID: 17234627.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    83. Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. Mol Cell Biol. 2007 Jan; 27(2):497-509. Berchtold CM, Wu ZH, Huang TT, Miyamoto S. PMID: 17074802; PMCID: PMC1800799.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    84. NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells. Cancer Res. 2006 Jun 15; 66(12):6008-13. Chang PY, Draheim K, Kelliher MA, Miyamoto S. PMID: 16778171.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    85. Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. Science. 2006 Feb 24; 311(5764):1141-6. Wu ZH, Shi Y, Tibbetts RS, Miyamoto S. PMID: 16497931.
      View in: PubMed   Mentions: 268     Fields:    Translation:HumansCells
    86. Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy. J Mol Cell Cardiol. 2006 May; 40(5):597-604. Howes AL, Miyamoto S, Adams JW, Woodcock EA, Brown JH. PMID: 16466740.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    87. Ca2+ dysregulation induces mitochondrial depolarization and apoptosis: role of Na+/Ca2+ exchanger and AKT. J Biol Chem. 2005 Nov 18; 280(46):38505-12. Miyamoto S, Howes AL, Adams JW, Dorn GW, Brown JH. PMID: 16061478.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    88. Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction. Mol Cancer Res. 2005 Jun; 3(6):345-53. Wuerzberger-Davis SM, Chang PY, Berchtold C, Miyamoto S. PMID: 15972853.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    89. Inhibition of IkappaBalpha nuclear export as an approach to abrogate nuclear factor-kappaB-dependent cancer cell survival. Mol Cancer Res. 2005 Jan; 3(1):42-9. O'Connor S, Shumway S, Miyamoto S. PMID: 15671248.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    90. Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs. Eur J Pharmacol. 2005 Jan 04; 506(3):249-55. Nagasawa Y, Zhu BM, Chen J, Kamiya K, Miyamoto S, Hashimoto K. PMID: 15627435.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    91. Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. Mol Cell Biol. 2004 Jun; 24(11):4895-908. O'Connor S, Shumway SD, Amanna IJ, Hayes CE, Miyamoto S. PMID: 15143182; PMCID: PMC416427.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    92. RelA life and death decisions. Mol Cell. 2004 Mar 26; 13(6):763-4. Miyamoto S. PMID: 15053867.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    93. Cardiomyocyte calcium and calcium/calmodulin-dependent protein kinase II: friends or foes? Recent Prog Horm Res. 2004; 59:141-68. Zhang T, Miyamoto S, Brown JH. PMID: 14749501.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    94. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell. 2003 Nov 26; 115(5):565-76. Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S. PMID: 14651848.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansAnimalsCells
    95. Rapid formation of hepatic organoid in collagen sponge by rat small hepatocytes and hepatic nonparenchymal cells. J Hepatol. 2003 Nov; 39(5):716-23. Harada K, Mitaka T, Miyamoto S, Sugimoto S, Ikeda S, Takeda H, Mochizuki Y, Hirata K. PMID: 14568252.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    96. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene. 2003 Sep 01; 22(37):5813-27. Criswell T, Leskov K, Miyamoto S, Luo G, Boothman DA. PMID: 12947388.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    97. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. J Biol Chem. 2003 Oct 10; 278(41):40343-51. Howes AL, Arthur JF, Zhang T, Miyamoto S, Adams JW, Dorn GW, Woodcock EA, Brown JH. PMID: 12900409.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    98. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J Biol Chem. 2003 Aug 15; 278(33):31111-7. Kawamura S, Miyamoto S, Brown JH. PMID: 12777392.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    99. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res. 2003 May 02; 92(8):912-9. Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J, Bers DM, Brown JH. PMID: 12676814.
      View in: PubMed   Mentions: 273     Fields:    Translation:AnimalsCells
    100. KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs. Jpn J Pharmacol. 2002 Nov; 90(3):229-35. Miyamoto S, Zhu BM, Kamiya K, Nagasawa Y, Hashimoto K. PMID: 12499577.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    101. The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors. Mol Cell Biol. 2002 Aug; 22(16):5813-25. Huang TT, Feinberg SL, Suryanarayanan S, Miyamoto S. PMID: 12138192; PMCID: PMC133970.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    102. CD14-dependent activation of NF-kappaB by filarial parasitic sheath proteins. Cell Biol Int. 2002; 26(1):43-54. Narayanan K, Seufzer BJ, Brockman-Schneider RA, Gern JE, Balakrishnan A, Miyamoto S. PMID: 11779220.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    103. Inhibitory effects of pre-ischemic and post-ischemic treatment with FR 168888, a Na+/H+ exchange inhibitor, on reperfusion-induced ventricular arrhythmias in anesthetized rat. Jpn J Pharmacol. 2002 Jan; 88(1):93-9. Zhu BM, Miyamoto S, Kamiya K, Komori S, Hashimoto K. PMID: 11855683.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    104. Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells. Mol Pharmacol. 2002 Jan; 61(1):177-85. Shumway SD, Berchtold CM, Gould MN, Miyamoto S. PMID: 11752219.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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