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Dwayne Stupack

Title(s)Professor, Pathology
SchoolHealth Sciences
Phone858-822-1150
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    Collapse Research 
    Collapse Research Activities and Funding
    In Vivo Cellular and Molecular Imaging Centers (ICMICs)
    NIH/NCI P50CA128346Sep 23, 2008 - Aug 31, 2014
    Role: Co-Investigator
    Integrins and Caspase 8 in Tumor Progression
    NIH/NCI R01CA107263Apr 1, 2004 - Apr 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wang J, Li D, Shen W, Sun W, Gao R, Jiang P, Wang L, Liu Y, Chen Y, Zhou W, Wang R, Xiang R, Stupack D, Luo N. RHAMM inhibits cell migration via the AKT/GSK3ß/Snail axis in luminal A subtype breast cancer. Anat Rec (Hoboken). 2019 Nov 26. PMID: 31769593.
      View in: PubMed
    2. Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. Elife. 2019 09 03; 8. PMID: 31478830.
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    3. Belli M, Secchi C, Stupack D, Shimasaki S. FOXO1 Negates the Cooperative Action of FOXL2C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3. J Endocr Soc. 2019 Nov 01; 3(11):2064-2081. PMID: 31701078.
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    4. Kleinschmidt EG, Miller NLG, Ozmadenci D, Tancioni I, Osterman CD, Barrie AM, Taylor KN, Ye A, Jiang S, Connolly DC, Stupack DG, Schlaepfer DD. Rgnef promotes ovarian tumor progression and confers protection from oxidative stress. Oncogene. 2019 Sep; 38(36):6323-6337. PMID: 31308489.
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    5. Gao R, Li D, Xun J, Zhou W, Li J, Wang J, Liu C, Li X, Shen W, Qiao H, Stupack DG, Luo N. CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism. Theranostics. 2018; 8(22):6248-6262. PMID: 30613295.
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    6. Gao R, Liu Y, Li D, Xun J, Zhou W, Wang P, Liu C, Li X, Shen W, Su W, Qiao H, Stupack DG, Luo N. PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner. Cell Physiol Biochem. 2018; 50(6):2108-2123. PMID: 30415245.
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    7. Belli M, Iwata N, Nakamura T, Iwase A, Stupack D, Shimasaki S. FOXL2C134W-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells. Endocrinology. 2018 04 01; 159(4):1690-1703. PMID: 29471425.
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    8. Keller N, Ozmadenci D, Ichim G, Stupack D. Caspase-8 function, and phosphorylation, in cell migration. Semin Cell Dev Biol. 2018 10; 82:105-117. PMID: 29410361.
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    9. Burgoyne AM, De Siena M, Alkhuziem M, Tang CM, Medina B, Fanta PT, Belinsky MG, von Mehren M, Thorson JA, Madlensky L, Bowler T, D'Angelo F, Stupack DG, Harismendy O, DeMatteo RP, Sicklick JK. Duodenal-Jejunal Flexure GI Stromal Tumor Frequently Heralds Somatic NF1 and Notch Pathway Mutations. JCO Precis Oncol. 2017; 2017. PMID: 29938249.
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    10. Hu S, Dong X, Gao W, Stupack D, Liu Y, Xiang R, Li N. Alternative promotion and suppression of metastasis by JNK2 governed by its phosphorylation. Oncotarget. 2017 Aug 22; 8(34):56569-56581. PMID: 28915613.
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    11. Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017 02 15; 8:14423. PMID: 28198375.
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    12. Delaney JR, Stupack DG. Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One. 2016; 11(7):e0159114. PMID: 27391266.
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    13. Davis MA, Delaney JR, Patel CB, Storgard R, Stupack DG. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016; 10:1837-46. PMID: 27330277.
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    14. Zhang Y, Shen L, Stupack DG, Bai N, Xun J, Ren G, Han J, Li L, Luo Y, Xiang R, Tan X. JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms. Oncotarget. 2016 May 17; 7(20):29387-99. PMID: 27102442.
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    15. Shen W, Chang A, Wang J, Zhou W, Gao R, Li J, Xu Y, Luo X, Xiang R, Luo N, Stupack DG. TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer. Oncogenesis. 2015 Oct 26; 4:e173. PMID: 26501855.
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    16. Delaney JR, Patel C, McCabe KE, Lu D, Davis MA, Tancioni I, von Schalscha T, Bartakova A, Haft C, Schlaepfer DD, Stupack DG. A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget. 2015 Oct 13; 6(31):31104-18. PMID: 26418751.
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    17. Wang R, Zhou W, Wang J, Liu Y, Chen Y, Jiang S, Luo X, Stupack DG, Luo N. Role of Hyaluronan and Glucose on 4-Methylumbelliferone-inhibited Cell Proliferation in Breast Carcinoma Cells. Anticancer Res. 2015 Sep; 35(9):4799-805. PMID: 26254370.
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    18. Young SA, McCabe KE, Bartakova A, Delaney J, Pizzo DP, Newbury RO, Varner JA, Schlaepfer DD, Stupack DG. Integrin a4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One. 2015; 10(5):e0120815. PMID: 25973900.
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    19. McCabe KE, Bacos K, Lu D, Delaney JR, Axelrod J, Potter MD, Vamos M, Wong V, Cosford ND, Xiang R, Stupack DG. Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis. 2014 Oct 30; 5:e1496. PMID: 25356865.
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    20. Sayyah J, Bartakova A, Nogal N, Quilliam LA, Stupack DG, Brown JH. The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth. J Biol Chem. 2014 Jun 20; 289(25):17689-98. PMID: 24790104.
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    21. Díaz J, Mendoza P, Ortiz R, Díaz N, Leyton L, Stupack D, Quest AF, Torres VA. Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion. J Cell Sci. 2014 Jun 01; 127(Pt 11):2401-6. PMID: 24659799.
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    22. Graf RP, Keller N, Barbero S, Stupack D. Caspase-8 as a regulator of tumor cell motility. Curr Mol Med. 2014 Feb; 14(2):246-54. PMID: 24467204.
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    23. Cheresh DA, Stupack DG. Tumor angiogenesis: putting a value on plastic GEMMs. Circ Res. 2014 Jan 03; 114(1):9-11. PMID: 24385501.
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    24. Chen S, Li X, Lu D, Xu Y, Mou W, Wang L, Chen Y, Liu Y, Li X, Li LY, Liu L, Stupack D, Reisfeld RA, Xiang R, Li N. SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells. Carcinogenesis. 2014 Mar; 35(3):613-23. PMID: 24233838.
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    25. Mendoza P, Ortiz R, Díaz J, Quest AF, Leyton L, Stupack D, Torres VA. Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. J Cell Sci. 2013 Sep 01; 126(Pt 17):3835-47. PMID: 23813952.
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    26. Graf R, Barbero S, Keller N, Chen L, Uryu S, Schlaepfer D, Stupack D. Src-inducible association of CrkL with procaspase-8 promotes cell migration. Cell Adh Migr. 2013 Jul-Aug; 7(4):362-9. PMID: 23751956.
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    27. Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C. Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biol Ther. 2013 Jun; 14(6):511-20. PMID: 23760493.
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    28. Ward KK, Tancioni I, Lawson C, Miller NL, Jean C, Chen XL, Uryu S, Kim J, Tarin D, Stupack DG, Plaxe SC, Schlaepfer DD. Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression. Clin Exp Metastasis. 2013 Jun; 30(5):579-94. PMID: 23275034.
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    29. Wang L, Chen S, Zhang M, Li N, Chen Y, Su W, Liu Y, Lu D, Li S, Yang Y, Li Z, Stupack D, Qu P, Hu H, Xiang R. Legumain: a biomarker for diagnosis and prognosis of human ovarian cancer. J Cell Biochem. 2012 Aug; 113(8):2679-86. PMID: 22441772.
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    30. Lu D, Chen S, Tan X, Li N, Liu C, Li Z, Liu Z, Stupack DG, Reisfeld RA, Xiang R. Fra-1 promotes breast cancer chemosensitivity by driving cancer stem cells from dormancy. Cancer Res. 2012 Jul 15; 72(14):3451-6. PMID: 22586064.
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    31. Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. EGFR-mediated carcinoma cell metastasis mediated by integrin avß5 depends on activation of c-Src and cleavage of MUC1. PLoS One. 2012; 7(5):e36753. PMID: 22586492.
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    32. Yuan RT, Young S, Liang J, Schmid MC, Mielgo A, Stupack DG. Caspase-8 isoform 6 promotes death effector filament formation independent of microtubules. Apoptosis. 2012 Mar; 17(3):229-35. PMID: 22160860.
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    33. Kinsella JM, Jimenez RE, Karmali PP, Rush AM, Kotamraju VR, Gianneschi NC, Ruoslahti E, Stupack D, Sailor MJ. X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles. Angew Chem Int Ed Engl. 2011 Dec 16; 50(51):12308-11. PMID: 22028313.
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    34. Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 2012 May 31; 31(22):2783-93. PMID: 21963850.
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    35. DE Wever O, Sobczak-Thépot J, Vercoutter-Edouart AS, Michalski JC, Ouelaa-Benslama R, Stupack DG, Bracke M, Wang JYJ, Gespach C, Emami S. Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. Int J Oncol. 2011 Aug; 39(2):393-400. PMID: 21567080.
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    36. Torres VA, Stupack DG. Rab5 in the regulation of cell motility and invasion. Curr Protein Pept Sci. 2011 Feb; 12(1):43-51. PMID: 21190523.
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    37. Stupack DG. Caspase-8 as a therapeutic target in cancer. Cancer Lett. 2013 May 28; 332(2):133-40. PMID: 20817393.
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    38. Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, Phillips A, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models. Cancer Biol Ther. 2010 May 15; 9(10):778-90. PMID: 20234193.
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    39. Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer Biol Ther. 2010 May 15; 9(10):764-77. PMID: 20234191.
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    40. Thalhauser CJ, Lowengrub JS, Stupack D, Komarova NL. Selection in spatial stochastic models of cancer: migration as a key modulator of fitness. Biol Direct. 2010 Apr 20; 5:21. PMID: 20406439.
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    41. De Magalhães N, Liaw LH, Berns M, Cristini V, Chen Z, Stupack D, Lowengrub J. Applications of a new In vivo tumor spheroid based shell-less chorioallantoic membrane 3-D model in bioengineering research. J Biomed Sci Eng. 2010 Jan 01; 3(1):20-26. PMID: 21243108.
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    42. Mielgo A, Torres VA, Schmid MC, Graf R, Zeitlin SG, Lee P, Shields DJ, Barbero S, Jamora C, Stupack DG. The death effector domains of caspase-8 induce terminal differentiation. PLoS One. 2009 Nov 18; 4(11):e7879. PMID: 19924290.
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    43. Torres VA, Mielgo A, Barbero S, Hsiao R, Wilkins JA, Stupack DG. Rab5 mediates caspase-8-promoted cell motility and metastasis. Mol Biol Cell. 2010 Jan 15; 21(2):369-76. PMID: 19923319.
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    44. Mielgo A, Torres VA, Clair K, Barbero S, Stupack DG. Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene. 2009 Oct 08; 28(40):3551-62. PMID: 19668227.
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    45. Weis SM, Stupack DG, Cheresh DA. Agonizing integrin antagonists? Cancer Cell. 2009 May 05; 15(5):359-61. PMID: 19411065.
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    46. Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barilà D, Lahti JM, Schlaepfer D, Stupack DG. Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res. 2009 May 01; 69(9):3755-63. PMID: 19383910.
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    47. Delloye-Bourgeois C, Fitamant J, Paradisi A, Cappellen D, Douc-Rasy S, Raquin MA, Stupack D, Nakagawara A, Rousseau R, Combaret V, Puisieux A, Valteau-Couanet D, Bénard J, Bernet A, Mehlen P. Netrin-1 acts as a survival factor for aggressive neuroblastoma. J Exp Med. 2009 Apr 13; 206(4):833-47. PMID: 19349462.
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    48. Huang X, Wu D, Jin H, Stupack D, Wang JY. Induction of cell retraction by the combined actions of Abl-CrkII and Rho-ROCK1 signaling. J Cell Biol. 2008 Nov 17; 183(4):711-23. PMID: 19001122.
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    49. Torres VA, Mielgo A, Barilà D, Anderson DH, Stupack D. Caspase 8 promotes peripheral localization and activation of Rab5. J Biol Chem. 2008 Dec 26; 283(52):36280-9. PMID: 18974049.
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    50. Cheresh DA, Stupack DG. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene. 2008 Oct 20; 27(48):6285-98. PMID: 18931694.
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    51. Walsh CT, Radeff-Huang J, Matteo R, Hsiao A, Subramaniam S, Stupack D, Brown JH. Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61. FASEB J. 2008 Nov; 22(11):4011-21. PMID: 18687805.
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    52. Walsh CT, Stupack D, Brown JH. G protein-coupled receptors go extracellular: RhoA integrates the integrins. Mol Interv. 2008 Aug; 8(4):165-73. PMID: 18829842.
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    53. Lim ST, Mikolon D, Stupack DG, Schlaepfer DD. FERM control of FAK function: implications for cancer therapy. Cell Cycle. 2008 Aug; 7(15):2306-14. PMID: 18677107.
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    54. Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2313-8. PMID: 18268346.
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    55. Barbero S, Barilà D, Mielgo A, Stagni V, Clair K, Stupack D. Identification of a critical tyrosine residue in caspase 8 that promotes cell migration. J Biol Chem. 2008 May 09; 283(19):13031-4. PMID: 18216014.
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    56. Mielgo A, Brondani V, Landmann L, Glaser-Ruhm A, Erb P, Stupack D, Günthert U. The CD44 standard/ezrin complex regulates Fas-mediated apoptosis in Jurkat cells. Apoptosis. 2007 Nov; 12(11):2051-61. PMID: 17726647.
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    57. Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD. Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility. Oncogene. 2008 Feb 28; 27(10):1439-48. PMID: 17828307.
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    58. Stupack DG. The biology of integrins. Oncology (Williston Park). 2007 Aug; 21(9 Suppl 3):6-12. PMID: 17927025.
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    59. Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A. Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol. 2007 Oct; 81(19):10249-57. PMID: 17626077.
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    60. Alavi A, Stupack DG. Cell survival in a three-dimensional matrix. Methods Enzymol. 2007; 426:85-101. PMID: 17697881.
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    61. Lahti JM, Teitz T, Stupack DG. Does integrin-mediated cell death confer tissue tropism in metastasis? Cancer Res. 2006 Jun 15; 66(12):5981-4. PMID: 16778165.
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    62. Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 2006 Sep 28; 25(44):5969-84. PMID: 16682956.
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    63. Teitz T, Stupack DG, Lahti JM. Halting neuroblastoma metastasis by controlling integrin-mediated death. Cell Cycle. 2006 Apr; 5(7):681-5. PMID: 16582638.
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    64. Jin H, Aiyer A, Su J, Borgstrom P, Stupack D, Friedlander M, Varner J. A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature. J Clin Invest. 2006 Mar; 116(3):652-62. PMID: 16498499.
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    65. Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature. 2006 Jan 05; 439(7072):95-9. PMID: 16397500.
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    66. Stupack DG. Integrins as a distinct subtype of dependence receptors. Cell Death Differ. 2005 Aug; 12(8):1021-30. PMID: 15933741.
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    67. Storgard C, Mikolon D, Stupack DG. Angiogenesis assays in the chick CAM. Methods Mol Biol. 2005; 294:123-36. PMID: 15576910.
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    68. Stupack DG, Cheresh DA. A Bit-role for integrins in apoptosis. Nat Cell Biol. 2004 May; 6(5):388-9. PMID: 15122265.
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    69. Stupack DG, Cheresh DA. Integrins and angiogenesis. Curr Top Dev Biol. 2004; 64:207-38. PMID: 15563949.
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    70. Stupack DG, Cheresh DA. Apoptotic cues from the extracellular matrix: regulators of angiogenesis. Oncogene. 2003 Dec 08; 22(56):9022-9. PMID: 14663480.
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    71. Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. Role of Raf in vascular protection from distinct apoptotic stimuli. Science. 2003 Jul 04; 301(5629):94-6. PMID: 12843393.
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    72. Zhong J, Eliceiri B, Stupack D, Penta K, Sakamoto G, Quertermous T, Coleman M, Boudreau N, Varner JA. Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J Clin Invest. 2003 Jul; 112(1):30-41. PMID: 12840057.
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    73. Desrumaux CM, Mak PA, Boisvert WA, Masson D, Stupack D, Jauhiainen M, Ehnholm C, Curtiss LK. Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. J Lipid Res. 2003 Aug; 44(8):1453-61. PMID: 12730304.
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    74. Stupack DG, Cheresh DA. Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci. 2002 Oct 01; 115(Pt 19):3729-38. PMID: 12235283.
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    75. Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol. 2002 Apr 01; 157(1):149-60. PMID: 11927607.
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    76. Cheresh DA, Stupack DG. Integrin-mediated death: an explanation of the integrin-knockout phenotype? Nat Med. 2002 Mar; 8(3):193-4. PMID: 11875466.
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    77. Stupack DG, Cheresh DA. ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands. Sci STKE. 2002 Feb 12; 2002(119):pe7. PMID: 11842241.
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    78. Stupack DG, Puente XS, Boutsaboualoy S, Storgard CM, Cheresh DA. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol. 2001 Oct 29; 155(3):459-70. PMID: 11684710.
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    79. Li E, Brown SL, Stupack DG, Puente XS, Cheresh DA, Nemerow GR. Integrin alpha(v)beta1 is an adenovirus coreceptor. J Virol. 2001 Jun; 75(11):5405-9. PMID: 11333925.
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    80. Goralski KB, Stupack DG, Hatch GM, Sitar DS. Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy. Can J Physiol Pharmacol. 2001 Jan; 79(1):18-24. PMID: 11201497.
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    81. Li E, Stupack DG, Brown SL, Klemke R, Schlaepfer DD, Nemerow GR. Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry. J Biol Chem. 2000 May 12; 275(19):14729-35. PMID: 10799562.
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    82. Huang S, Stupack D, Liu A, Cheresh D, Nemerow GR. Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of alpha(v) integrins. Oncogene. 2000 Apr 06; 19(15):1915-23. PMID: 10773881.
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    83. Stupack DG, Cho SY, Klemke RL. Molecular signaling mechanisms of cell migration and invasion. Immunol Res. 2000; 21(2-3):83-8. PMID: 10852105.
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    84. Pampori N, Hato T, Stupack DG, Aidoudi S, Cheresh DA, Nemerow GR, Shattil SJ. Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand. J Biol Chem. 1999 Jul 30; 274(31):21609-16. PMID: 10419468.
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    85. Stupack DG, Escobar MR, Carlisle M, Davie T, Sitar DS. Heterogeneity among beta-adrenoreceptor blockers in the modulation of energy-dependent uptake of the organic cation amantadine by rat renal tubules. Can J Physiol Pharmacol. 1999 Jun; 77(6):407-13. PMID: 10537226.
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    86. Stupack DG, Storgard CM, Cheresh DA. A role for angiogenesis in rheumatoid arthritis. Braz J Med Biol Res. 1999 May; 32(5):573-81. PMID: 10412569.
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    87. Stupack DG, Li E, Silletti SA, Kehler JA, Geahlen RL, Hahn K, Nemerow GR, Cheresh DA. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase. J Cell Biol. 1999 Feb 22; 144(4):777-88. PMID: 10037798.
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    88. Storgard CM, Stupack DG, Jonczyk A, Goodman SL, Fox RI, Cheresh DA. Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist. J Clin Invest. 1999 Jan; 103(1):47-54. PMID: 9884333.
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    89. Li E, Stupack D, Bokoch GM, Nemerow GR. Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases. J Virol. 1998 Nov; 72(11):8806-12. PMID: 9765425.
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    90. Li E, Stupack D, Klemke R, Cheresh DA, Nemerow GR. Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase. J Virol. 1998 Mar; 72(3):2055-61. PMID: 9499060.
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    91. Huang S, Stupack D, Mathias P, Wang Y, Nemerow G. Growth arrest of Epstein-Barr virus immortalized B lymphocytes by adenovirus-delivered ribozymes. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):8156-61. PMID: 9223331.
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    92. Wilkins JA, Li A, Ni H, Stupack DG, Shen C. Control of beta1 integrin function. Localization of stimulatory epitopes. J Biol Chem. 1996 Feb 09; 271(6):3046-51. PMID: 8621699.
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    93. Stupack DG, Shen C, Wilkins JA. Control of lymphocyte integrin function: evidence for multiple contributing factors. Cell Immunol. 1994 Apr 15; 155(1):237-45. PMID: 7513261.
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