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Dwayne Stupack

Title(s)Professor, Pathology
SchoolHealth Sciences
Address9500 Gilman Drive #0803
La Jolla CA 92093
Phone858-822-1150
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    Collapse Biography 
    Collapse Education and Training
    U Manitoba, CanadaPhD05/96Medical Microbiology

    Collapse Research 
    Collapse Research Activities and Funding
    FOXL2 in Adult Granulosa Cell Tumorigenesis
    NIH/NCI R01CA244182Jun 1, 2020 - May 31, 2025
    Role: Co-Principal Investigator
    Dissecting FAK-regulated oncogenic signaling programs in ovarian cancer
    NIH/NCI R01CA247562May 1, 2020 - Apr 30, 2025
    Role: Co-Principal Investigator
    In Vivo Cellular and Molecular Imaging Centers (ICMICs)
    NIH/NCI P50CA128346Jun 1, 2009 - Aug 31, 2014
    Role: Co-Investigator
    Integrins and Caspase 8 in Tumor Progression
    NIH/NCI R01CA107263Apr 1, 2004 - Nov 30, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Underlying Subwavelength Aperture Architecture Drives the Optical Properties of Microcavity Surface Plasmon Resonance Sensors. Sensors (Basel). 2020 Aug 30; 20(17). Amarie D, Mosavian N, Waters EL, Stupack DG. PMID: 32872658.
      View in: PubMed   Mentions:    Fields:    
    2. Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLoS Genet. 2020 01; 16(1):e1008558. Delaney JR, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR, Stupack DG. PMID: 31923184.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. RHAMM inhibits cell migration via the AKT/GSK3ß/Snail axis in luminal A subtype breast cancer. Anat Rec (Hoboken). 2020 Sep; 303(9):2344-2356. Wang J, Li D, Shen W, Sun W, Gao R, Jiang P, Wang L, Liu Y, Chen Y, Zhou W, Wang R, Xiang R, Stupack D, Luo N. PMID: 31769593.
      View in: PubMed   Mentions:    Fields:    
    4. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. Elife. 2019 09 03; 8. Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. PMID: 31478830.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    5. FOXO1 Negates the Cooperative Action of FOXL2C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3. J Endocr Soc. 2019 Nov 01; 3(11):2064-2081. Belli M, Secchi C, Stupack D, Shimasaki S. PMID: 31701078.
      View in: PubMed   Mentions:
    6. Rgnef promotes ovarian tumor progression and confers protection from oxidative stress. Oncogene. 2019 09; 38(36):6323-6337. Kleinschmidt EG, Miller NLG, Ozmadenci D, Tancioni I, Osterman CD, Barrie AM, Taylor KN, Ye A, Jiang S, Connolly DC, Stupack DG, Schlaepfer DD. PMID: 31308489.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism. Theranostics. 2018; 8(22):6248-6262. Gao R, Li D, Xun J, Zhou W, Li J, Wang J, Liu C, Li X, Shen W, Qiao H, Stupack DG, Luo N. PMID: 30613295.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner. Cell Physiol Biochem. 2018; 50(6):2108-2123. Gao R, Liu Y, Li D, Xun J, Zhou W, Wang P, Liu C, Li X, Shen W, Su W, Qiao H, Stupack DG, Luo N. PMID: 30415245.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. FOXL2C134W-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells. Endocrinology. 2018 04 01; 159(4):1690-1703. Belli M, Iwata N, Nakamura T, Iwase A, Stupack D, Shimasaki S. PMID: 29471425.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Caspase-8 function, and phosphorylation, in cell migration. Semin Cell Dev Biol. 2018 10; 82:105-117. Keller N, Ozmadenci D, Ichim G, Stupack D. PMID: 29410361.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. Duodenal-Jejunal Flexure GI Stromal Tumor Frequently Heralds Somatic NF1 and Notch Pathway Mutations. JCO Precis Oncol. 2017; 2017. Burgoyne AM, De Siena M, Alkhuziem M, Tang CM, Medina B, Fanta PT, Belinsky MG, von Mehren M, Thorson JA, Madlensky L, Bowler T, D'Angelo F, Stupack DG, Harismendy O, DeMatteo RP, Sicklick JK. PMID: 29938249.
      View in: PubMed   Mentions:
    12. Alternative promotion and suppression of metastasis by JNK2 governed by its phosphorylation. Oncotarget. 2017 Aug 22; 8(34):56569-56581. Hu S, Dong X, Gao W, Stupack D, Liu Y, Xiang R, Li N. PMID: 28915613.
      View in: PubMed   Mentions: 1     Fields:    
    13. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017 02 15; 8:14423. Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. PMID: 28198375.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    14. Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One. 2016; 11(7):e0159114. Delaney JR, Stupack DG. PMID: 27391266.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016; 10:1837-46. Davis MA, Delaney JR, Patel CB, Storgard R, Stupack DG. PMID: 27330277.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    16. JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms. Oncotarget. 2016 May 17; 7(20):29387-99. Zhang Y, Shen L, Stupack DG, Bai N, Xun J, Ren G, Han J, Li L, Luo Y, Xiang R, Tan X. PMID: 27102442.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    17. TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer. Oncogenesis. 2015 Oct 26; 4:e173. Shen W, Chang A, Wang J, Zhou W, Gao R, Li J, Xu Y, Luo X, Xiang R, Luo N, Stupack DG. PMID: 26501855.
      View in: PubMed   Mentions:
    18. A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget. 2015 Oct 13; 6(31):31104-18. Delaney JR, Patel C, McCabe KE, Lu D, Davis MA, Tancioni I, von Schalscha T, Bartakova A, Haft C, Schlaepfer DD, Stupack DG. PMID: 26418751.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    19. Role of Hyaluronan and Glucose on 4-Methylumbelliferone-inhibited Cell Proliferation in Breast Carcinoma Cells. Anticancer Res. 2015 Sep; 35(9):4799-805. Wang R, Zhou W, Wang J, Liu Y, Chen Y, Jiang S, Luo X, Stupack DG, Luo N. PMID: 26254370.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    20. Integrin a4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One. 2015; 10(5):e0120815. Young SA, McCabe KE, Bartakova A, Delaney J, Pizzo DP, Newbury RO, Varner JA, Schlaepfer DD, Stupack DG. PMID: 25973900.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    21. Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis. 2014 Oct 30; 5:e1496. McCabe KE, Bacos K, Lu D, Delaney JR, Axelrod J, Potter MD, Vamos M, Wong V, Cosford ND, Xiang R, Stupack DG. PMID: 25356865.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth. J Biol Chem. 2014 Jun 20; 289(25):17689-98. Sayyah J, Bartakova A, Nogal N, Quilliam LA, Stupack DG, Brown JH. PMID: 24790104.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    23. Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion. J Cell Sci. 2014 Jun 01; 127(Pt 11):2401-6. Díaz J, Mendoza P, Ortiz R, Díaz N, Leyton L, Stupack D, Quest AF, Torres VA. PMID: 24659799.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    24. Caspase-8 as a regulator of tumor cell motility. Curr Mol Med. 2014 Feb; 14(2):246-54. Graf RP, Keller N, Barbero S, Stupack D. PMID: 24467204.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    25. Tumor angiogenesis: putting a value on plastic GEMMs. Circ Res. 2014 Jan 03; 114(1):9-11. Cheresh DA, Stupack DG. PMID: 24385501.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    26. SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells. Carcinogenesis. 2014 Mar; 35(3):613-23. Chen S, Li X, Lu D, Xu Y, Mou W, Wang L, Chen Y, Liu Y, Li X, Li LY, Liu L, Stupack D, Reisfeld RA, Xiang R, Li N. PMID: 24233838.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    27. Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. J Cell Sci. 2013 Sep 01; 126(Pt 17):3835-47. Mendoza P, Ortiz R, Díaz J, Quest AF, Leyton L, Stupack D, Torres VA. PMID: 23813952.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    28. Src-inducible association of CrkL with procaspase-8 promotes cell migration. Cell Adh Migr. 2013 Jul-Aug; 7(4):362-9. Graf R, Barbero S, Keller N, Chen L, Uryu S, Schlaepfer D, Stupack D. PMID: 23751956.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    29. Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biol Ther. 2013 Jun; 14(6):511-20. Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C. PMID: 23760493.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    30. Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression. Clin Exp Metastasis. 2013 Jun; 30(5):579-94. Ward KK, Tancioni I, Lawson C, Miller NL, Jean C, Chen XL, Uryu S, Kim J, Tarin D, Stupack DG, Plaxe SC, Schlaepfer DD. PMID: 23275034.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    31. Legumain: a biomarker for diagnosis and prognosis of human ovarian cancer. J Cell Biochem. 2012 Aug; 113(8):2679-86. Wang L, Chen S, Zhang M, Li N, Chen Y, Su W, Liu Y, Lu D, Li S, Yang Y, Li Z, Stupack D, Qu P, Hu H, Xiang R. PMID: 22441772.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    32. Fra-1 promotes breast cancer chemosensitivity by driving cancer stem cells from dormancy. Cancer Res. 2012 Jul 15; 72(14):3451-6. Lu D, Chen S, Tan X, Li N, Liu C, Li Z, Liu Z, Stupack DG, Reisfeld RA, Xiang R. PMID: 22586064.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    33. EGFR-mediated carcinoma cell metastasis mediated by integrin avß5 depends on activation of c-Src and cleavage of MUC1. PLoS One. 2012; 7(5):e36753. Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. PMID: 22586492.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    34. Caspase-8 isoform 6 promotes death effector filament formation independent of microtubules. Apoptosis. 2012 Mar; 17(3):229-35. Yuan RT, Young S, Liang J, Schmid MC, Mielgo A, Stupack DG. PMID: 22160860.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    35. X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles. Angew Chem Int Ed Engl. 2011 Dec 16; 50(51):12308-11. Kinsella JM, Jimenez RE, Karmali PP, Rush AM, Kotamraju VR, Gianneschi NC, Ruoslahti E, Stupack D, Sailor MJ. PMID: 22028313.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    36. EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 2012 May 31; 31(22):2783-93. Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. PMID: 21963850.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    37. Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. Int J Oncol. 2011 Aug; 39(2):393-400. DE Wever O, Sobczak-Thépot J, Vercoutter-Edouart AS, Michalski JC, Ouelaa-Benslama R, Stupack DG, Bracke M, Wang JYJ, Gespach C, Emami S. PMID: 21567080.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    38. Rab5 in the regulation of cell motility and invasion. Curr Protein Pept Sci. 2011 Feb; 12(1):43-51. Torres VA, Stupack DG. PMID: 21190523.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    39. Caspase-8 as a therapeutic target in cancer. Cancer Lett. 2013 May 28; 332(2):133-40. Stupack DG. PMID: 20817393.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    40. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer Biol Ther. 2010 May 15; 9(10):764-77. Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. PMID: 20234191.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    41. Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models. Cancer Biol Ther. 2010 May 15; 9(10):778-90. Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, Phillips A, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. PMID: 20234193.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    42. Selection in spatial stochastic models of cancer: migration as a key modulator of fitness. Biol Direct. 2010 Apr 20; 5:21. Thalhauser CJ, Lowengrub JS, Stupack D, Komarova NL. PMID: 20406439.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    43. Applications of a new In vivo tumor spheroid based shell-less chorioallantoic membrane 3-D model in bioengineering research. J Biomed Sci Eng. 2010 Jan 01; 3(1):20-26. De Magalhães N, Liaw LH, Berns M, Cristini V, Chen Z, Stupack D, Lowengrub J. PMID: 21243108.
      View in: PubMed   Mentions:
    44. Rab5 mediates caspase-8-promoted cell motility and metastasis. Mol Biol Cell. 2010 Jan 15; 21(2):369-76. Torres VA, Mielgo A, Barbero S, Hsiao R, Wilkins JA, Stupack DG. PMID: 19923319.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    45. The death effector domains of caspase-8 induce terminal differentiation. PLoS One. 2009 Nov 18; 4(11):e7879. Mielgo A, Torres VA, Schmid MC, Graf R, Zeitlin SG, Lee P, Shields DJ, Barbero S, Jamora C, Stupack DG. PMID: 19924290.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    46. Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene. 2009 Oct 08; 28(40):3551-62. Mielgo A, Torres VA, Clair K, Barbero S, Stupack DG. PMID: 19668227.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    47. Agonizing integrin antagonists? Cancer Cell. 2009 May 05; 15(5):359-61. Weis SM, Stupack DG, Cheresh DA. PMID: 19411065.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    48. Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res. 2009 May 01; 69(9):3755-63. Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barilà D, Lahti JM, Schlaepfer D, Stupack DG. PMID: 19383910.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    49. Netrin-1 acts as a survival factor for aggressive neuroblastoma. J Exp Med. 2009 Apr 13; 206(4):833-47. Delloye-Bourgeois C, Fitamant J, Paradisi A, Cappellen D, Douc-Rasy S, Raquin MA, Stupack D, Nakagawara A, Rousseau R, Combaret V, Puisieux A, Valteau-Couanet D, Bénard J, Bernet A, Mehlen P. PMID: 19349462.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    50. Induction of cell retraction by the combined actions of Abl-CrkII and Rho-ROCK1 signaling. J Cell Biol. 2008 Nov 17; 183(4):711-23. Huang X, Wu D, Jin H, Stupack D, Wang JY. PMID: 19001122.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    51. Caspase 8 promotes peripheral localization and activation of Rab5. J Biol Chem. 2008 Dec 26; 283(52):36280-9. Torres VA, Mielgo A, Barilà D, Anderson DH, Stupack D. PMID: 18974049.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    52. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene. 2008 Oct 20; 27(48):6285-98. Cheresh DA, Stupack DG. PMID: 18931694.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    53. Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61. FASEB J. 2008 Nov; 22(11):4011-21. Walsh CT, Radeff-Huang J, Matteo R, Hsiao A, Subramaniam S, Stupack D, Brown JH. PMID: 18687805.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    54. G protein-coupled receptors go extracellular: RhoA integrates the integrins. Mol Interv. 2008 Aug; 8(4):165-73. Walsh CT, Stupack D, Brown JH. PMID: 18829842.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    55. FERM control of FAK function: implications for cancer therapy. Cell Cycle. 2008 Aug; 7(15):2306-14. Lim ST, Mikolon D, Stupack DG, Schlaepfer DD. PMID: 18677107.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    56. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2313-8. Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG. PMID: 18268346.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    57. Identification of a critical tyrosine residue in caspase 8 that promotes cell migration. J Biol Chem. 2008 May 09; 283(19):13031-4. Barbero S, Barilà D, Mielgo A, Stagni V, Clair K, Stupack D. PMID: 18216014.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    58. The CD44 standard/ezrin complex regulates Fas-mediated apoptosis in Jurkat cells. Apoptosis. 2007 Nov; 12(11):2051-61. Mielgo A, Brondani V, Landmann L, Glaser-Ruhm A, Erb P, Stupack D, Günthert U. PMID: 17726647.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    59. Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility. Oncogene. 2008 Feb 28; 27(10):1439-48. Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD. PMID: 17828307.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    60. The biology of integrins. Oncology (Williston Park). 2007 Aug; 21(9 Suppl 3):6-12. Stupack DG. PMID: 17927025.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    61. Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol. 2007 Oct; 81(19):10249-57. Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A. PMID: 17626077.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    62. Cell survival in a three-dimensional matrix. Methods Enzymol. 2007; 426:85-101. Alavi A, Stupack DG. PMID: 17697881.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    63. Does integrin-mediated cell death confer tissue tropism in metastasis? Cancer Res. 2006 Jun 15; 66(12):5981-4. Lahti JM, Teitz T, Stupack DG. PMID: 16778165.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    64. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 2006 Sep 28; 25(44):5969-84. Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. PMID: 16682956.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    65. Halting neuroblastoma metastasis by controlling integrin-mediated death. Cell Cycle. 2006 Apr; 5(7):681-5. Teitz T, Stupack DG, Lahti JM. PMID: 16582638.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    66. A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature. J Clin Invest. 2006 Mar; 116(3):652-62. Jin H, Aiyer A, Su J, Borgstrom P, Stupack D, Friedlander M, Varner J. PMID: 16498499.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    67. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature. 2006 Jan 05; 439(7072):95-9. Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA. PMID: 16397500.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    68. Integrins as a distinct subtype of dependence receptors. Cell Death Differ. 2005 Aug; 12(8):1021-30. Stupack DG. PMID: 15933741.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    69. Angiogenesis assays in the chick CAM. Methods Mol Biol. 2005; 294:123-36. Storgard C, Mikolon D, Stupack DG. PMID: 15576910.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    70. A Bit-role for integrins in apoptosis. Nat Cell Biol. 2004 May; 6(5):388-9. Stupack DG, Cheresh DA. PMID: 15122265.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    71. Integrins and angiogenesis. Curr Top Dev Biol. 2004; 64:207-38. Stupack DG, Cheresh DA. PMID: 15563949.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    72. Apoptotic cues from the extracellular matrix: regulators of angiogenesis. Oncogene. 2003 Dec 08; 22(56):9022-9. Stupack DG, Cheresh DA. PMID: 14663480.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    73. Role of Raf in vascular protection from distinct apoptotic stimuli. Science. 2003 Jul 04; 301(5629):94-6. Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. PMID: 12843393.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    74. Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J Clin Invest. 2003 Jul; 112(1):30-41. Zhong J, Eliceiri B, Stupack D, Penta K, Sakamoto G, Quertermous T, Coleman M, Boudreau N, Varner JA. PMID: 12840057.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    75. Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. J Lipid Res. 2003 Aug; 44(8):1453-61. Desrumaux CM, Mak PA, Boisvert WA, Masson D, Stupack D, Jauhiainen M, Ehnholm C, Curtiss LK. PMID: 12730304.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    76. Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci. 2002 Oct 01; 115(Pt 19):3729-38. Stupack DG, Cheresh DA. PMID: 12235283.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    77. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol. 2002 Apr 01; 157(1):149-60. Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. PMID: 11927607.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    78. Integrin-mediated death: an explanation of the integrin-knockout phenotype? Nat Med. 2002 Mar; 8(3):193-4. Cheresh DA, Stupack DG. PMID: 11875466.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    79. ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands. Sci STKE. 2002 Feb 12; 2002(119):pe7. Stupack DG, Cheresh DA. PMID: 11842241.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    80. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol. 2001 Oct 29; 155(3):459-70. Stupack DG, Puente XS, Boutsaboualoy S, Storgard CM, Cheresh DA. PMID: 11684710.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    81. Integrin alpha(v)beta1 is an adenovirus coreceptor. J Virol. 2001 Jun; 75(11):5405-9. Li E, Brown SL, Stupack DG, Puente XS, Cheresh DA, Nemerow GR. PMID: 11333925.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    82. Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy. Can J Physiol Pharmacol. 2001 Jan; 79(1):18-24. Goralski KB, Stupack DG, Hatch GM, Sitar DS. PMID: 11201497.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    83. Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry. J Biol Chem. 2000 May 12; 275(19):14729-35. Li E, Stupack DG, Brown SL, Klemke R, Schlaepfer DD, Nemerow GR. PMID: 10799562.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    84. Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of alpha(v) integrins. Oncogene. 2000 Apr 06; 19(15):1915-23. Huang S, Stupack D, Liu A, Cheresh D, Nemerow GR. PMID: 10773881.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    85. Molecular signaling mechanisms of cell migration and invasion. Immunol Res. 2000; 21(2-3):83-8. Stupack DG, Cho SY, Klemke RL. PMID: 10852105.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    86. Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand. J Biol Chem. 1999 Jul 30; 274(31):21609-16. Pampori N, Hato T, Stupack DG, Aidoudi S, Cheresh DA, Nemerow GR, Shattil SJ. PMID: 10419468.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    87. Heterogeneity among beta-adrenoreceptor blockers in the modulation of energy-dependent uptake of the organic cation amantadine by rat renal tubules. Can J Physiol Pharmacol. 1999 Jun; 77(6):407-13. Stupack DG, Escobar MR, Carlisle M, Davie T, Sitar DS. PMID: 10537226.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    88. A role for angiogenesis in rheumatoid arthritis. Braz J Med Biol Res. 1999 May; 32(5):573-81. Stupack DG, Storgard CM, Cheresh DA. PMID: 10412569.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    89. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase. J Cell Biol. 1999 Feb 22; 144(4):777-88. Stupack DG, Li E, Silletti SA, Kehler JA, Geahlen RL, Hahn K, Nemerow GR, Cheresh DA. PMID: 10037798.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    90. Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist. J Clin Invest. 1999 Jan; 103(1):47-54. Storgard CM, Stupack DG, Jonczyk A, Goodman SL, Fox RI, Cheresh DA. PMID: 9884333.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    91. Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases. J Virol. 1998 Nov; 72(11):8806-12. Li E, Stupack D, Bokoch GM, Nemerow GR. PMID: 9765425.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    92. Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase. J Virol. 1998 Mar; 72(3):2055-61. Li E, Stupack D, Klemke R, Cheresh DA, Nemerow GR. PMID: 9499060.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    93. Growth arrest of Epstein-Barr virus immortalized B lymphocytes by adenovirus-delivered ribozymes. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):8156-61. Huang S, Stupack D, Mathias P, Wang Y, Nemerow G. PMID: 9223331.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    94. Control of beta1 integrin function. Localization of stimulatory epitopes. J Biol Chem. 1996 Feb 09; 271(6):3046-51. Wilkins JA, Li A, Ni H, Stupack DG, Shen C. PMID: 8621699.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    95. Control of lymphocyte integrin function: evidence for multiple contributing factors. Cell Immunol. 1994 Apr 15; 155(1):237-45. Stupack DG, Shen C, Wilkins JA. PMID: 7513261.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    96. Induction of alpha v beta 3 integrin-mediated attachment to extracellular matrix in beta 1 integrin (CD29)-negative B cell lines. Exp Cell Res. 1992 Dec; 203(2):443-8. Stupack DG, Shen C, Wilkins JA. PMID: 1281112.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    97. The interactions of gamma delta T cells with extracellular matrix: receptor expression and utilization patterns. Scand J Immunol. 1992 Aug; 36(2):213-9. Wilkins J, Selin L, Stewart S, Sivananthan K, Stupack D. PMID: 1380178.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    98. B lymphocyte fibronectin receptors: expression and utilization. Scand J Immunol. 1991 Dec; 34(6):761-9. Stupack DG, Stewart S, Carter WG, Wayner EA, Wilkins JA. PMID: 1836275.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    99. Beta 1 integrin-mediated lymphocyte adherence to extracellular matrix is enhanced by phorbol ester treatment. Eur J Immunol. 1991 Feb; 21(2):517-22. Wilkins JA, Stupack D, Stewart S, Caixia S. PMID: 1999229.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
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