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Wolfgang Dillmann

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0671
La Jolla CA 92093
Phone858-246-0449
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    Collapse Research 
    Collapse Research Activities and Funding
    Heart Vascular Function and Thyroid Hormone Receptors
    VA I01BX001121Jul 1, 2011 - Jun 30, 2015
    Role: Principal Investigator
    Heart Failure and Thyroid Hormone
    NIH/NHLBI R01HL089938Sep 1, 2007 - Aug 31, 2011
    Role: Principal Investigator
    Diabetic Cardiomyopathy
    NIH/NHLBI R01HL066917Sep 30, 2000 - Jun 30, 2013
    Role: Principal Investigator
    Cardiac hypertrophy and SERCa2 gene expression
    NIH/NHLBI R01HL052946Aug 1, 1995 - Nov 30, 2008
    Role: Principal Investigator
    CARDIAC ISCHEMIA AND HSPS
    NIH/NHLBI R37HL049434Dec 1, 1993 - Nov 30, 2008
    Role: Principal Investigator
    CARDIAC ISCHEMIA AND HSP70
    NIH/NHLBI R01HL049434Dec 1, 1993 - Nov 30, 1998
    Role: Principal Investigator
    CARDIAC MYOSIN &PROTEIN FORMATION IN DIABETES MELLITUS
    NIH/NHLBI R01HL027800Aug 1, 1981 - Jul 31, 1987
    Role: Principal Investigator
    THYROID ACTION IN THE HEART
    NIH/NHLBI R01HL025022May 1, 1979 - Aug 31, 2007
    Role: Principal Investigator
    Experimental Endocrinology and Metabolism
    NIH/NIDDK T32DK007044Sep 15, 1978 - Mar 31, 2021
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Suarez J, Cividini F, Scott BT, Lehmann K, Diaz-Juarez J, Diemer T, Dai A, Suarez JA, Jain M, Dillmann W. Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function. J Biol Chem. 2018 May 25; 293(21):8182-8195. PMID: 29626093.
      View in: PubMed
    2. Kalyanaraman H, Schwaerzer G, Ramdani G, Castillo F, Scott BT, Dillmann W, Sah RL, Casteel DE, Pilz RB. Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes. 2018 04; 67(4):607-623. PMID: 29301852.
      View in: PubMed
    3. Gao MH, Lai NC, Giamouridis D, Kim YC, Tan Z, Guo T, Dillmann W, Suarez J, Hammond HK. Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation. JACC Basic Transl Sci. 2016 Dec; 1(7):617-629. PMID: 28670631.
      View in: PubMed
    4. Cividini F, Scott BT, Dai A, Han W, Suarez J, Diaz-Juarez J, Diemer T, Casteel DE, Dillmann W. O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts. J Biol Chem. 2016 Dec 16; 291(51):26515-26528. PMID: 27816939.
      View in: PubMed
    5. Diaz-Juarez J, Suarez J, Cividini F, Scott BT, Diemer T, Dai A, Dillmann W. Expression of the mitochondrial calcium uniporter in cardiac myocytes improves impaired mitochondrial calcium handling and metabolism in simulated hyperglycemia. Am J Physiol Cell Physiol. 2016 Dec 01; 311(6):C1005-C1013. PMID: 27681178.
      View in: PubMed
    6. Radwanski PB, Ho HT, Veeraraghavan R, Brunello L, Liu B, Belevych AE, Unudurthi SD, Makara MA, Priori SG, Volpe P, Armoundas AA, Dillmann W, Knollmann BC, Mohler PJ, Hund TJ, Györke S. Neuronal Na+ Channels Are Integral Components of Pro-arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During ß-adrenergic Stimulation. JACC Basic Transl Sci. 2016 Jun; 1(4):251-266. PMID: 27747307.
      View in: PubMed
    7. Stary V, Puppala D, Scherrer-Crosbie M, Dillmann W, Armoundas AA. SERCA2a upregulation ameliorates cellular alternans induced by metabolic inhibition. J Appl Physiol (1985). 2016 Apr 15; 120(8):865-75. PMID: 26846549; PMCID: PMC4835906 [Available on 04/15/17].
    8. Makino A, Dai A, Han Y, Youssef KD, Wang W, Donthamsetty R, Scott BT, Wang H, Dillmann W. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice. Am J Physiol Cell Physiol. 2015 Nov 01; 309(9):C593-9. PMID: 26269457; PMCID: PMC4628934 [Available on 11/01/16].
    9. Lai NC, Gao MH, Giamouridis D, Suarez J, Miyanohara A, Parikh J, Hightower S, Guo T, Dillmann W, Kim YC, Diaz-Juarez J, Hammond HK. Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice. Hum Gene Ther. 2015 Jun; 26(6):347-56. PMID: 25760560; PMCID: PMC4492611.
    10. Suarez J, Wang H, Scott BT, Ling H, Makino A, Swanson E, Brown JH, Suarez JA, Feinstein S, Diaz-Juarez J, Dillmann W. In vivo selective expression of thyroid hormone receptor a1 in endothelial cells attenuates myocardial injury in experimental myocardial infarction in mice. Am J Physiol Regul Integr Comp Physiol. 2014 Aug 01; 307(3):R340-6. PMID: 24848360; PMCID: PMC4121632.
    11. Kalyanaraman H, Schwappacher R, Joshua J, Zhuang S, Scott BT, Klos M, Casteel DE, Frangos JA, Dillmann W, Boss GR, Pilz RB. Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Sci Signal. 2014 May 20; 7(326):ra48. PMID: 24847117.
      View in: PubMed
    12. Aguilar H, Fricovsky E, Ihm S, Schimke M, Maya-Ramos L, Aroonsakool N, Ceballos G, Dillmann W, Villarreal F, Ramirez-Sanchez I. Role for high-glucose-induced protein O-GlcNAcylation in stimulating cardiac fibroblast collagen synthesis. Am J Physiol Cell Physiol. 2014 May 01; 306(9):C794-804. PMID: 24553187; PMCID: PMC4010805.
    13. Torres-Gonzalez M, Gawlowski T, Kocalis H, Scott BT, Dillmann W. Mitochondrial 8-oxoguanine glycosylase decreases mitochondrial fragmentation and improves mitochondrial function in H9C2 cells under oxidative stress conditions. Am J Physiol Cell Physiol. 2014 Feb 01; 306(3):C221-9. PMID: 24304833; PMCID: PMC3920001.
    14. Okada H, Lai NC, Kawaraguchi Y, Liao P, Copps J, Sugano Y, Okada-Maeda S, Banerjee I, Schilling JM, Gingras AR, Asfaw EK, Suarez J, Kang SM, Perkins GA, Au CG, Israeli-Rosenberg S, Manso AM, Liu Z, Milner DJ, Kaufman SJ, Patel HH, Roth DM, Hammond HK, Taylor SS, Dillmann W, Goldhaber JI, Ross RS. Integrins protect cardiomyocytes from ischemia/reperfusion injury. J Clin Invest. 2013 Oct; 123(10):4294-308. PMID: 24091324; PMCID: PMC3784521.
    15. Gao MH, Lai NC, Tang T, Guo T, Tang R, Chun BJ, Wang H, Dalton NN, Suarez J, Dillmann W, Hammond HK. Preserved cardiac function despite marked impairment of cAMP generation. PLoS One. 2013; 8(9):e72151. PMID: 24147149; PMCID: PMC3797917.
    16. Gao MH, Lai NC, Miyanohara A, Schilling JM, Suarez J, Tang T, Guo T, Tang R, Parikh J, Giamouridis D, Dillmann W, Patel HH, Roth DM, Dalton ND, Hammond HK. Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice. Hum Gene Ther. 2013 Sep; 24(9):777-85. PMID: 23931341; PMCID: PMC3768340.
    17. Golden HB, Watson LE, Nizamutdinov D, Feng H, Gerilechaogetu F, Lal H, Verma SK, Mukhopadhyay S, Foster DM, Dillmann W, Dostal DE. Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling network. Int J Cardiol. 2013 Oct 09; 168(4):3884-95. PMID: 23907041; PMCID: PMC4112368.
    18. Sen S, Kundu BK, Wu HC, Hashmi SS, Guthrie P, Locke LW, Roy RJ, Matherne GP, Berr SS, Terwelp M, Scott B, Carranza S, Frazier OH, Glover DK, Dillmann W, Gambello MJ, Entman ML, Taegtmeyer H. Glucose regulation of load-induced mTOR signaling and ER stress in mammalian heart. J Am Heart Assoc. 2013 May 17; 2(3):e004796. PMID: 23686371; PMCID: PMC3698799.
    19. Romero-Suarez S, Mo C, Touchberry C, Lara N, Baker K, Craig R, Brotto L, Andresen J, Wacker M, Kaja S, Abreu E, Dillmann W, Mestril R, Brotto M, Nosek T. Hyperthermia: from diagnostic and treatments to new discoveries. Recent Pat Biotechnol. 2012 Dec; 6(3):172-83. PMID: 23092438.
      View in: PubMed
    20. Suarez J, McDonough PM, Scott BT, Suarez-Ramirez A, Wang H, Fricovsky ES, Dillmann W. Sorcin modulates mitochondrial Ca(2+) handling and reduces apoptosis in neonatal rat cardiac myocytes. Am J Physiol Cell Physiol. 2013 Feb 01; 304(3):C248-56. PMID: 23151801; PMCID: PMC3566440.
    21. Fricovsky ES, Suarez J, Ihm SH, Scott BT, Suarez-Ramirez JA, Banerjee I, Torres-Gonzalez M, Wang H, Ellrott I, Maya-Ramos L, Villarreal F, Dillmann W. Excess protein O-GlcNAcylation and the progression of diabetic cardiomyopathy. Am J Physiol Regul Integr Comp Physiol. 2012 Oct 01; 303(7):R689-99. PMID: 22874425; PMCID: PMC3469670.
    22. Lunova M, Zizer E, Kucukoglu O, Schwarz C, Dillmann W, Wagner M, Strnad P. Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis. PLoS One. 2012; 7(7):e39972. PMID: 22792201; PMCID: PMC3390337.
    23. Gawlowski T, Suarez J, Scott B, Torres-Gonzalez M, Wang H, Schwappacher R, Han X, Yates JR, Hoshijima M, Dillmann W. Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-ß-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes. J Biol Chem. 2012 Aug 24; 287(35):30024-34. PMID: 22745122; PMCID: PMC3436129.
    24. Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9448-53. PMID: 22566629; PMCID: PMC3386114.
    25. Zhang GX, Obata K, Takeshita D, Mitsuyama S, Nakashima T, Kikuta A, Hirabayashi M, Tomita K, Vetter R, Dillmann W, Takaki M. Evaluation of left ventricular mechanical work and energetics of normal hearts in SERCA2a transgenic rats. J Physiol Sci. 2012 May; 62(3):221-31. PMID: 22383047.
      View in: PubMed
    26. Makino A, Wang H, Scott BT, Yuan JX, Dillmann W. Thyroid hormone receptor-a and vascular function. Am J Physiol Cell Physiol. 2012 May 01; 302(9):C1346-52. PMID: 22322976; PMCID: PMC3361953.
    27. Gao L, Díaz-Martín J, Dillmann W, López-Barneo J. Heat shock protein 70 kDa over-expression and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigrostriatal degeneration in mice. Neuroscience. 2011 Oct 13; 193:323-9. PMID: 21782904.
      View in: PubMed
    28. Makino A, Suarez J, Gawlowski T, Han W, Wang H, Scott BT, Dillmann W. Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes. Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6):R1296-302. PMID: 21346246; PMCID: PMC3119148.
    29. Pinz I, Tian R, Belke D, Swanson E, Dillmann W, Ingwall JS. Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a. J Biol Chem. 2011 Mar 25; 286(12):10163-8. PMID: 21278384; PMCID: PMC3060468.
    30. Yang LZ, Kockskämper J, Khan S, Suarez J, Walther S, Doleschal B, Unterer G, Khafaga M, Mächler H, Heinzel FR, Dillmann W, Pieske B, Spiess J. cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes. Br J Pharmacol. 2011 Jan; 162(2):544-56. PMID: 20942811; PMCID: PMC3031072.
    31. Suarez J, Scott BT, Suarez-Ramirez JA, Chavira CV, Dillmann W. Thyroid hormone inhibits ERK phosphorylation in pressure overload-induced hypertrophied mouse hearts through a receptor-mediated mechanism. Am J Physiol Cell Physiol. 2010 Dec; 299(6):C1524-9. PMID: 20926779; PMCID: PMC3006330.
    32. Makino A, Scott BT, Dillmann W. Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. Diabetologia. 2010 Aug; 53(8):1783-94. PMID: 20461356; PMCID: PMC2892085.
    33. Kayani AC, Close GL, Dillmann W, Mestril R, Jackson MJ, McArdle A. Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle Cross-Sectional Area. Am J Physiol Regul Integr Comp Physiol. 2010 Jul; 299(1):R268-76. PMID: 20410481; PMCID: PMC2904147.
    34. de Zoeten EF, Wang L, Sai H, Dillmann W, Hancock WW. Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice. Gastroenterology. 2010 Feb; 138(2):583-94. PMID: 19879272; PMCID: PMC3369426.
    35. Hilal-Dandan R, He H, Martin JL, Brunton LL, Dillmann W. Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: regulation by pertussis toxin-sensitive Gi protein and cAMP. Am J Physiol Heart Circ Physiol. 2009 Mar; 296(3):H728-34. PMID: 19151257; PMCID: PMC2660228.
    36. Taleb M, Brandon CS, Lee FS, Harris KC, Dillmann W, Cunningham LL. Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death. Cell Stress Chaperones. 2009 Jul; 14(4):427-37. PMID: 19145477; PMCID: PMC2728278.
    37. Dillmann W. Cardiac hypertrophy and thyroid hormone signaling. Heart Fail Rev. 2010 Mar; 15(2):125-32. PMID: 19125327; PMCID: PMC2820695.
    38. Makino A, Suarez J, Wang H, Belke DD, Scott BT, Dillmann W. Thyroid hormone receptor-beta is associated with coronary angiogenesis during pathological cardiac hypertrophy. Endocrinology. 2009 Apr; 150(4):2008-15. PMID: 19074585; PMCID: PMC2659277.
    39. Ngoh GA, Facundo HT, Hamid T, Dillmann W, Zachara NE, Jones SP. Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury. Circ Res. 2009 Jan 02; 104(1):41-9. PMID: 19023128; PMCID: PMC2712829.
    40. Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, Trauger SA, Han W, Hu Y, Oyeleye MO, Dillmann W. Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem. 2009 Jan 02; 284(1):547-55. PMID: 19004814; PMCID: PMC2610513.
    41. Suarez J, Hu Y, Makino A, Fricovsky E, Wang H, Dillmann W. Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes. Am J Physiol Cell Physiol. 2008 Dec; 295(6):C1561-8. PMID: 19060297; PMCID: PMC2603561.
    42. Romero-Perez D, Fricovsky E, Yamasaki KG, Griffin M, Barraza-Hidalgo M, Dillmann W, Villarreal F. Cardiac uptake of minocycline and mechanisms for in vivo cardioprotection. J Am Coll Cardiol. 2008 Sep 23; 52(13):1086-94. PMID: 18848143; PMCID: PMC2572824.
    43. Suarez J, Scott B, Dillmann W. Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy. Am J Physiol Regul Integr Comp Physiol. 2008 Nov; 295(5):R1439-45. PMID: 18799637; PMCID: PMC2584853.
    44. Xu M, Remillard CV, Sachs BD, Makino A, Platoshyn O, Yao W, Dillmann W, Akassoglou K, Yuan JX. p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction. Am J Physiol Heart Circ Physiol. 2008 Oct; 295(4):H1529-38. PMID: 18689502; PMCID: PMC2593496.
    45. Rouf R, Greytak S, Wooten EC, Wu J, Boltax J, Picard M, Svensson EC, Dillmann W, Patten RD, Huggins GS. Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription. Circ Res. 2008 Aug 29; 103(5):493-501. PMID: 18658259; PMCID: PMC2650841.
    46. Taleb M, Brandon CS, Lee FS, Lomax MI, Dillmann W, Cunningham LL. Hsp70 inhibits aminoglycoside-induced hair cell death and is necessary for the protective effect of heat shock. J Assoc Res Otolaryngol. 2008 Sep; 9(3):277-89. PMID: 18512096; PMCID: PMC2538150.
    47. Makino A, Platoshyn O, Suarez J, Yuan JX, Dillmann W. Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C221-30. PMID: 18463230; PMCID: PMC2493564.
    48. Ngoh GA, Watson LJ, Facundo HT, Dillmann W, Jones SP. Non-canonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition. J Mol Cell Cardiol. 2008 Aug; 45(2):313-25. PMID: 18539296; PMCID: PMC2610867.
    49. Broderick KE, Alvarez L, Balasubramanian M, Belke DD, Makino A, Chan A, Woods VL, Dillmann W, Sharma VS, Pilz RB, Bigby TD, Boss GR. Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo. Exp Biol Med (Maywood). 2007 Dec; 232(11):1432-40. PMID: 18040067.
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    50. Llagostera E, Catalucci D, Marti L, Liesa M, Camps M, Ciaraldi TP, Kondo R, Reddy S, Dillmann W, Palacin M, Zorzano A, Ruiz-Lozano P, Gomis R, Kaliman P. Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action. PLoS One. 2007 Nov 07; 2(11):e1134. PMID: 17987120; PMCID: PMC2043489.
    51. Williamson CL, Dabkowski ER, Dillmann W, Hollander JM. Mitochondria protection from hypoxia/reoxygenation injury with mitochondria heat shock protein 70 overexpression. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H249-56. PMID: 17982016.
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    52. Xu M, Platoshyn O, Makino A, Dillmann W, Akassoglou K, Remillard CV, Yuan JX. Characterization of agonist-induced vasoconstriction in mouse pulmonary artery. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H220-8. PMID: 17982012.
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    53. Belke DD, Gloss B, Swanson EA, Dillmann W. Adeno-associated virus-mediated expression of thyroid hormone receptor isoforms-alpha1 and -beta1 improves contractile function in pressure overload-induced cardiac hypertrophy. Endocrinology. 2007 Jun; 148(6):2870-7. PMID: 17317766.
      View in: PubMed
    54. Belke DD, Swanson E, Suarez J, Scott BT, Stenbit AE, Dillmann W. Increased expression of SERCA in the hearts of transgenic mice results in increased oxidation of glucose. Am J Physiol Heart Circ Physiol. 2007 Apr; 292(4):H1755-63. PMID: 17142343.
      View in: PubMed
    55. Belke DD, Gloss B, Hollander JM, Swanson EA, Duplain H, Dillmann W. In vivo gene delivery of HSP70i by adenovirus and adeno-associated virus preserves contractile function in mouse heart following ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2905-10. PMID: 16920815.
      View in: PubMed
    56. Kim YK, Suarez J, Hu Y, McDonough PM, Boer C, Dix DJ, Dillmann W. Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy. Circulation. 2006 Jun 06; 113(22):2589-97. PMID: 16735677.
      View in: PubMed
    57. Broome CS, Kayani AC, Palomero J, Dillmann W, Mestril R, Jackson MJ, McArdle A. Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity. FASEB J. 2006 Jul; 20(9):1549-51. PMID: 16723383.
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    58. Chia SH, Weisman RA, Tieu D, Kelly C, Dillmann W, Orloff LA. Prospective study of perioperative factors predicting hypocalcemia after thyroid and parathyroid surgery. Arch Otolaryngol Head Neck Surg. 2006 Jan; 132(1):41-5. PMID: 16415428.
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    59. Dieterle T, Meyer M, Gu Y, Belke DD, Swanson E, Iwatate M, Hollander J, Peterson KL, Ross J, Dillmann W. Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure. Cardiovasc Res. 2005 Sep 01; 67(4):678-88. PMID: 15927173.
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    60. Gloss B, Giannocco G, Swanson EA, Moriscot AS, Chiellini G, Scanlan T, Baxter JD, Dillmann W. Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression. Endocrinology. 2005 Nov; 146(11):4926-33. PMID: 16081636.
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    61. Weisser-Thomas J, Kubo H, Hefner CA, Gaughan JP, McGowan BS, Ross R, Meyer M, Dillmann W, Houser SR. The Na+/Ca2+ exchanger/SR Ca2+ ATPase transport capacity regulates the contractility of normal and hypertrophied feline ventricular myocytes. J Card Fail. 2005 Jun; 11(5):380-7. PMID: 15948089.
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    62. Hu Y, Jones SV, Dillmann W. Effects of hyperthyroidism on delayed rectifier K+ currents in left and right murine atria. Am J Physiol Heart Circ Physiol. 2005 Oct; 289(4):H1448-55. PMID: 15894573.
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    63. Cowling RT, Zhang X, Reese VC, Iwata M, Gurantz D, Dillmann W, Greenberg BH. Effects of cytokine treatment on angiotensin II type 1A receptor transcription and splicing in rat cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 2005 Sep; 289(3):H1176-83. PMID: 15879490.
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    64. Hu Y, Belke D, Suarez J, Swanson E, Clark R, Hoshijima M, Dillmann W. Adenovirus-mediated overexpression of O-GlcNAcase improves contractile function in the diabetic heart. Circ Res. 2005 May 13; 96(9):1006-13. PMID: 15817886.
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    65. Kahaly GJ, Dillmann W. Thyroid hormone action in the heart. Endocr Rev. 2005 Aug; 26(5):704-28. PMID: 15632316.
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    66. Belke DD, Swanson EA, Dillmann W. Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart. Diabetes. 2004 Dec; 53(12):3201-8. PMID: 15561951.
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    67. Belke DD, Dillmann W. Altered cardiac calcium handling in diabetes. Curr Hypertens Rep. 2004 Dec; 6(6):424-9. PMID: 15527685.
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    68. Hollander JM, Martin JL, Belke DD, Scott BT, Swanson E, Krishnamoorthy V, Dillmann W. Overexpression of wild-type heat shock protein 27 and a nonphosphorylatable heat shock protein 27 mutant protects against ischemia/reperfusion injury in a transgenic mouse model. Circulation. 2004 Dec 07; 110(23):3544-52. PMID: 15569832.
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    69. Chen Y, Epperson S, Makhsudova L, Ito B, Suarez J, Dillmann W, Villarreal F. Functional effects of enhancing or silencing adenosine A2b receptors in cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2478-86. PMID: 15284071.
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    70. Suarez J, Gloss B, Belke DD, Hu Y, Scott B, Dieterle T, Kim YK, Valencik ML, McDonald JA, Dillmann W. Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H2164-72. PMID: 15256372.
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    71. Meyer M, Belke DD, Trost SU, Swanson E, Dieterle T, Scott B, Cary SP, Ho P, Bluhm WF, McDonough PM, Silverman GJ, Dillmann W. A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation. FASEB J. 2004 Aug; 18(11):1312-4. PMID: 15180962.
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    72. Lin KM, Hollander JM, Kao VY, Lin B, Macpherson L, Dillmann W. Myocyte protection by 10 kD heat shock protein (Hsp10) involves the mobile loop and attenuation of the Ras GTP-ase pathway. FASEB J. 2004 Jun; 18(9):1004-6. PMID: 15059967.
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    73. Villarreal F, Omens J, Dillmann W, Risteli J, Nguyen J, Covell J. Early degradation and serum appearance of type I collagen fragments after myocardial infarction. J Mol Cell Cardiol. 2004 Apr; 36(4):597-601. PMID: 15081319.
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    74. Petrucelli L, Dickson D, Kehoe K, Taylor J, Snyder H, Grover A, De Lucia M, McGowan E, Lewis J, Prihar G, Kim J, Dillmann W, Browne SE, Hall A, Voellmy R, Tsuboi Y, Dawson TM, Wolozin B, Hardy J, Hutton M. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Hum Mol Genet. 2004 Apr 01; 13(7):703-14. PMID: 14962978.
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    75. McArdle A, Dillmann W, Mestril R, Faulkner JA, Jackson MJ. Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction. FASEB J. 2004 Feb; 18(2):355-7. PMID: 14688209.
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    76. Hollander JM, Lin KM, Scott BT, Dillmann W. Overexpression of PHGPx and HSP60/10 protects against ischemia/reoxygenation injury. Free Radic Biol Med. 2003 Oct 01; 35(7):742-51. PMID: 14583338.
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    77. Suarez J, Belke DD, Gloss B, Dieterle T, McDonough PM, Kim YK, Brunton LL, Dillmann W. In vivo adenoviral transfer of sorcin reverses cardiac contractile abnormalities of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2004 Jan; 286(1):H68-75. PMID: 12958030.
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    78. Villarreal FJ, Griffin M, Omens J, Dillmann W, Nguyen J, Covell J. Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling. Circulation. 2003 Sep 23; 108(12):1487-92. PMID: 12952845.
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    79. Clark RJ, McDonough PM, Swanson E, Trost SU, Suzuki M, Fukuda M, Dillmann W. Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation. J Biol Chem. 2003 Nov 07; 278(45):44230-7. PMID: 12941958.
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    80. Swanson EA, Gloss B, Belke DD, Kaneshige M, Cheng SY, Dillmann W. Cardiac expression and function of thyroid hormone receptor beta and its PV mutant. Endocrinology. 2003 Nov; 144(11):4820-5. PMID: 12959993.
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    81. Andrews C, Ho PD, Dillmann W, Glembotski CC, McDonough PM. The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovasc Res. 2003 Jul 01; 59(1):46-56. PMID: 12829175.
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    82. Burke BE, Olson RD, Cusack BJ, Gambliel HA, Dillmann W. Anthracycline cardiotoxicity in transgenic mice overexpressing SR Ca2+-ATPase. Biochem Biophys Res Commun. 2003 Apr 04; 303(2):504-7. PMID: 12659846.
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    83. Vetter R, Rehfeld U, Reissfelder C, Weiss W, Wagner KD, Günther J, Hammes A, Tschöpe C, Dillmann W, Paul M. Transgenic overexpression of the sarcoplasmic reticulum Ca2+ATPase improves reticular Ca2+ handling in normal and diabetic rat hearts. FASEB J. 2002 Oct; 16(12):1657-9. PMID: 12206992.
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    84. Martin JL, Bluhm WF, He H, Mestril R, Dillmann W. Mutation of COOH-terminal lysines in overexpressed alpha B-crystallin abrogates ischemic protection in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2002 Jul; 283(1):H85-91. PMID: 12063278.
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    85. Dedeoglu A, Ferrante RJ, Andreassen OA, Dillmann W, Beal MF. Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. Exp Neurol. 2002 Jul; 176(1):262-5. PMID: 12093104.
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    86. Dillmann W. Cellular action of thyroid hormone on the heart. Thyroid. 2002 Jun; 12(6):447-52. PMID: 12165105.
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    87. Trost SU, Belke DD, Bluhm WF, Meyer M, Swanson E, Dillmann W. Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy. Diabetes. 2002 Apr; 51(4):1166-71. PMID: 11916940.
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    88. Dillmann W, Gloss BR. The role of thyroid hormone receptors in the heart. Methods Mol Biol. 2002; 202:55-70. PMID: 12094607.
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    89. Das DK, Dillmann W, Ho YS, Lin KM, Gloss BR. Using genetically engineered mice to study myocardial ischemia-reperfusion injury. Methods Enzymol. 2002; 353:346-65. PMID: 12078508.
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    90. Zhang T, Johnson EN, Gu Y, Morissette MR, Sah VP, Gigena MS, Belke DD, Dillmann W, Rogers TB, Schulman H, Ross J, Brown JH. The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem. 2002 Jan 11; 277(2):1261-7. PMID: 11694533.
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    91. Cowling RT, Gurantz D, Peng J, Dillmann W, Greenberg BH. Transcription factor NF-kappa B is necessary for up-regulation of type 1 angiotensin II receptor mRNA in rat cardiac fibroblasts treated with tumor necrosis factor-alpha or interleukin-1 beta. J Biol Chem. 2002 Feb 22; 277(8):5719-24. PMID: 11600498.
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    92. Thuerauf DJ, Hoover H, Meller J, Hernandez J, Su L, Andrews C, Dillmann W, McDonough PM, Glembotski CC. Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system. J Biol Chem. 2001 Dec 21; 276(51):48309-17. PMID: 11595740.
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    93. Ito K, Yan X, Feng X, Manning WJ, Dillmann W, Lorell BH. Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure. Circ Res. 2001 Aug 31; 89(5):422-9. PMID: 11532903.
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    94. Cummings CJ, Sun Y, Opal P, Antalffy B, Mestril R, Orr HT, Dillmann W, Zoghbi HY. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet. 2001 Jul 01; 10(14):1511-8. PMID: 11448943.
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    95. Gagneux P, Amess B, Diaz S, Moore S, Patel T, Dillmann W, Parekh R, Varki A. Proteomic comparison of human and great ape blood plasma reveals conserved glycosylation and differences in thyroid hormone metabolism. Am J Phys Anthropol. 2001 Jun; 115(2):99-109. PMID: 11385598.
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    96. Meyer M, Trost SU, Bluhm WF, Knot HJ, Swanson E, Dillmann W. Impaired sarcoplasmic reticulum function leads to contractile dysfunction and cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2001 May; 280(5):H2046-52. PMID: 11299205.
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    97. Lin KM, Lin B, Lian IY, Mestril R, Scheffler IE, Dillmann W. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation. Circulation. 2001 Apr 03; 103(13):1787-92. PMID: 11282911.
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    98. Gloss B, Trost S, Bluhm W, Swanson E, Clark R, Winkfein R, Janzen K, Giles W, Chassande O, Samarut J, Dillmann W. Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor alpha or beta. Endocrinology. 2001 Feb; 142(2):544-50. PMID: 11159823.
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    99. Ray PS, Martin JL, Swanson EA, Otani H, Dillmann W, Das DK. Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion. FASEB J. 2001 Feb; 15(2):393-402. PMID: 11156955.
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    100. Baxter JD, Dillmann W, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS. Selective modulation of thyroid hormone receptor action. J Steroid Biochem Mol Biol. 2001 Jan-Mar; 76(1-5):31-42. PMID: 11384861.
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    101. Nosek TM, Brotto MA, Essig DA, Mestril R, Conover RC, Dillmann W, Kolbeck RC. Functional properties of skeletal muscle from transgenic animals with upregulated heat shock protein 70. Physiol Genomics. 2000 Nov 09; 4(1):25-33. PMID: 11074010.
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    102. Brewis N, Ohst K, Fields K, Rapacciuolo A, Chou D, Bloor C, Dillmann W, Rockman H, Walter G. Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A. Am J Physiol Heart Circ Physiol. 2000 Sep; 279(3):H1307-18. PMID: 10993798.
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    103. Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann W. The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology. 2000 Sep; 141(9):3057-64. PMID: 10965874.
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    104. Rajdev S, Hara K, Kokubo Y, Mestril R, Dillmann W, Weinstein PR, Sharp FR. Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction. Ann Neurol. 2000 Jun; 47(6):782-91. PMID: 10852544.
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    105. Gloss B, Villegas S, Villarreal FJ, Moriscot A, Dillmann W. Thyroid hormone-induced stimulation of the sarcoplasmic reticulum Ca(2+) ATPase gene is inhibited by LIF and IL-6. Am J Physiol Endocrinol Metab. 2000 Apr; 278(4):E738-43. PMID: 10751209.
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    106. Villegas S, Villarreal FJ, Dillmann W. Leukemia Inhibitory Factor and Interleukin-6 downregulate sarcoplasmic reticulum Ca2+ ATPase (SERCA2) in cardiac myocytes. Basic Res Cardiol. 2000 Feb; 95(1):47-54. PMID: 10752545.
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    107. Bluhm WF, Kranias EG, Dillmann W, Meyer M. Phospholamban: a major determinant of the cardiac force-frequency relationship. Am J Physiol Heart Circ Physiol. 2000 Jan; 278(1):H249-55. PMID: 10644605.
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    108. Lewis SE, Mannion RJ, White FA, Coggeshall RE, Beggs S, Costigan M, Martin JL, Dillmann W, Woolf CJ. A role for HSP27 in sensory neuron survival. J Neurosci. 1999 Oct 15; 19(20):8945-53. PMID: 10516313.
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    109. He H, Meyer M, Martin JL, McDonough PM, Ho P, Lou X, Lew WY, Hilal-Dandan R, Dillmann W. Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)-ATPase activity and cardiac myocyte contractility. Circulation. 1999 Aug 31; 100(9):974-80. PMID: 10468529.
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    110. Bluhm WF, Meyer M, Sayen MR, Swanson EA, Dillmann W. Overexpression of sarcoplasmic reticulum Ca(2+)-ATPase improves cardiac contractile function in hypothyroid mice. Cardiovasc Res. 1999 Aug 01; 43(2):382-8. PMID: 10536668.
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    111. Dillmann W. Small heat shock proteins and protection against injury. Ann N Y Acad Sci. 1999 Jun 30; 874:66-8. PMID: 10415521.
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    112. Dillmann W. Calcium regulatory proteins and their alteration by transgenic approaches. Am J Cardiol. 1999 Jun 17; 83(12A):89H-91H. PMID: 10750595.
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    113. Meyer M, Bluhm WF, He H, Post SR, Giordano FJ, Lew WY, Dillmann W. Phospholamban-to-SERCA2 ratio controls the force-frequency relationship. Am J Physiol. 1999 Mar; 276(3 Pt 2):H779-85. PMID: 10070059.
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    114. Gloss B, Sayen MR, Trost SU, Bluhm WF, Meyer M, Swanson EA, Usala SJ, Dillmann W. Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family. Endocrinology. 1999 Feb; 140(2):897-902. PMID: 9927321.
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    115. Martin JL, Hickey E, Weber LA, Dillmann W, Mestril R. Influence of phosphorylation and oligomerization on the protective role of the small heat shock protein 27 in rat adult cardiomyocytes. Gene Expr. 1999; 7(4-6):349-55. PMID: 10440235.
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    116. Dillmann W. Heat shock proteins and protection against ischemic injury. Infect Dis Obstet Gynecol. 1999; 7(1-2):55-7. PMID: 10231010; PMCID: PMC1784710.
    117. Tian R, Halow JM, Meyer M, Dillmann W, Figueredo VM, Ingwall JS, Camacho SA. Thermodynamic limitation for Ca2+ handling contributes to decreased contractile reserve in rat hearts. Am J Physiol. 1998 Dec; 275(6 Pt 2):H2064-71. PMID: 9843805.
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    118. Bluhm WF, Martin JL, Mestril R, Dillmann W. Specific heat shock proteins protect microtubules during simulated ischemia in cardiac myocytes. Am J Physiol. 1998 Dec; 275(6 Pt 2):H2243-9. PMID: 9843825.
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    119. Yao A, Su Z, Dillmann W, Barry WH. Sarcoplasmic reticulum function in murine ventricular myocytes overexpressing SR CaATPase. J Mol Cell Cardiol. 1998 Dec; 30(12):2711-8. PMID: 9990541.
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    120. Bluhm WF, Meyer M, Swanson EA, Dillmann W. Postrest potentiation of active force in mouse papillary muscles is greatly accelerated by increased stimulus frequency. Ann N Y Acad Sci. 1998 Sep 16; 853:304-7. PMID: 10603965.
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    121. Dillmann W. Influences of increased expression of the Ca2+ ATPase of the sarcoplasmic reticulum by a transgenic approach on cardiac contractility. Ann N Y Acad Sci. 1998 Sep 16; 853:43-8. PMID: 10603935.
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    122. Ho PD, Zechner DK, He H, Dillmann W, Glembotski CC, McDonough PM. The Raf-MEK-ERK cascade represents a common pathway for alteration of intracellular calcium by Ras and protein kinase C in cardiac myocytes. J Biol Chem. 1998 Aug 21; 273(34):21730-5. PMID: 9705309.
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    123. Su CY, Chong KY, Owen OE, Dillmann W, Chang C, Lai CC. Constitutive and inducible hsp70s are involved in oxidative resistance evoked by heat shock or ethanol. J Mol Cell Cardiol. 1998 Mar; 30(3):587-98. PMID: 9515034.
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    124. Trost SU, Omens JH, Karlon WJ, Meyer M, Mestril R, Covell JW, Dillmann W. Protection against myocardial dysfunction after a brief ischemic period in transgenic mice expressing inducible heat shock protein 70. J Clin Invest. 1998 Feb 15; 101(4):855-62. PMID: 9466981; PMCID: PMC508634.
    125. Meyer M, Dillmann W. Sarcoplasmic reticulum Ca(2+)-ATPase overexpression by adenovirus mediated gene transfer and in transgenic mice. Cardiovasc Res. 1998 Feb; 37(2):360-6. PMID: 9614493.
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    126. Martin JL, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann W. Small heat shock proteins and protection against ischemic injury in cardiac myocytes. Circulation. 1997 Dec 16; 96(12):4343-8. PMID: 9416902.
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    127. He H, Giordano FJ, Hilal-Dandan R, Choi DJ, Rockman HA, McDonough PM, Bluhm WF, Meyer M, Sayen MR, Swanson E, Dillmann W. Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. J Clin Invest. 1997 Jul 15; 100(2):380-9. PMID: 9218515; PMCID: PMC508201.
    128. Giordano FJ, He H, McDonough P, Meyer M, Sayen MR, Dillmann W. Adenovirus-mediated gene transfer reconstitutes depressed sarcoplasmic reticulum Ca2+-ATPase levels and shortens prolonged cardiac myocyte Ca2+ transients. Circulation. 1997 Jul 15; 96(2):400-3. PMID: 9244202.
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    129. Conde AG, Lau SS, Dillmann W, Mestril R. Induction of heat shock proteins by tyrosine kinase inhibitors in rat cardiomyocytes and myogenic cells confers protection against simulated ischemia. J Mol Cell Cardiol. 1997 Jul; 29(7):1927-38. PMID: 9236146.
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    130. Wu PS, Moriscot AS, Knowlton KU, Hilal-Dandan R, He H, Dillmann W. Alpha 1-adrenergic stimulation inhibits 3,5,3'-triiodothyronine-induced expression of the rat heart sarcoplasmic reticulum Ca2+ adenosine triphosphatase gene. Endocrinology. 1997 Jan; 138(1):114-20. PMID: 8977393.
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    131. Moriscot AS, Sayen MR, Hartong R, Wu P, Dillmann W. Transcription of the rat sarcoplasmic reticulum Ca2+ adenosine triphosphatase gene is increased by 3,5,3'-triiodothyronine receptor isoform-specific interactions with the myocyte-specific enhancer factor-2a. Endocrinology. 1997 Jan; 138(1):26-32. PMID: 8977381.
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    132. Hartong R, Villarreal FJ, Giordano F, Hilal-Dandan R, McDonough PM, Dillmann W. Phorbol myristate acetate-induced hypertrophy of neonatal rat cardiac myocytes is associated with decreased sarcoplasmic reticulum Ca2+ ATPase (SERCA2) gene expression and calcium reuptake. J Mol Cell Cardiol. 1996 Dec; 28(12):2467-77. PMID: 9004163.
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    133. Mestril R, Giordano FJ, Conde AG, Dillmann W. Adenovirus-mediated gene transfer of a heat shock protein 70 (hsp 70i) protects against simulated ischemia. J Mol Cell Cardiol. 1996 Dec; 28(12):2351-8. PMID: 9004152.
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    134. Hutter JJ, Mestril R, Tam EK, Sievers RE, Dillmann W, Wolfe CL. Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo. Circulation. 1996 Sep 15; 94(6):1408-11. PMID: 8823000.
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    135. Giordano FJ, Ping P, McKirnan MD, Nozaki S, DeMaria AN, Dillmann W, Mathieu-Costello O, Hammond HK. Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart. Nat Med. 1996 May; 2(5):534-9. PMID: 8616711.
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    136. Dillmann W. Regulation of expression of cardiac sarcoplasmic reticulum proteins under pathophysiological conditions. Mol Cell Biochem. 1996 Apr 12-26; 157(1-2):125-8. PMID: 8739238.
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    137. Villarreal FJ, Lee AA, Dillmann W, Giordano FJ. Adenovirus-mediated overexpression of human transforming growth factor-beta 1 in rat cardiac fibroblasts, myocytes and smooth muscle cells. J Mol Cell Cardiol. 1996 Apr; 28(4):735-42. PMID: 8732501.
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    138. Dillmann W. Editorial: thyroid hormone action and cardiac contractility - a complex affair. Endocrinology. 1996 Mar; 137(3):799-801. PMID: 8603587.
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    139. Lee AA, Dillmann W, McCulloch AD, Villarreal FJ. Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts. J Mol Cell Cardiol. 1995 Oct; 27(10):2347-57. PMID: 8576949.
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    140. Kim NN, Villarreal FJ, Printz MP, Lee AA, Dillmann W. Trophic effects of angiotensin II on neonatal rat cardiac myocytes are mediated by cardiac fibroblasts. Am J Physiol. 1995 Sep; 269(3 Pt 1):E426-37. PMID: 7573419.
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    141. Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann W. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest. 1995 Apr; 95(4):1446-56. PMID: 7706448; PMCID: PMC295626.
    142. Mestril R, Dillmann W. Heat shock proteins and protection against myocardial ischemia. J Mol Cell Cardiol. 1995 Jan; 27(1):45-52. PMID: 7760364.
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    143. Villarreal FJ, MacKenna DA, Omens JH, Dillmann W. Myocardial remodeling in hypertensive Ren-2 transgenic rats. Hypertension. 1995 Jan; 25(1):98-104. PMID: 7843762.
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    144. Dillmann W, Mestril R. Heat shock proteins in myocardial stress. Z Kardiol. 1995; 84 Suppl 4:87-90. PMID: 8585278.
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    145. Hartong R, Wang N, Kurokawa R, Lazar MA, Glass CK, Apriletti JW, Dillmann W. Delineation of three different thyroid hormone-response elements in promoter of rat sarcoplasmic reticulum Ca2+ATPase gene. Demonstration that retinoid X receptor binds 5' to thyroid hormone receptor in response element 1. J Biol Chem. 1994 Apr 29; 269(17):13021-9. PMID: 8175722.
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    146. Mestril R, Chi SH, Sayen MR, Dillmann W. Isolation of a novel inducible rat heat-shock protein (HSP70) gene and its expression during ischaemia/hypoxia and heat shock. Biochem J. 1994 Mar 15; 298 Pt 3:561-9. PMID: 8141767; PMCID: PMC1137895.
    147. Mestril R, Chi SH, Sayen MR, O'Reilly K, Dillmann W. Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against simulated ischemia-induced injury. J Clin Invest. 1994 Feb; 93(2):759-67. PMID: 8113409; PMCID: PMC293923.
    148. Villarreal FJ, Kim NN, Ungab GD, Printz MP, Dillmann W. Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation. 1993 Dec; 88(6):2849-61. PMID: 8252698.
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    149. Iwaki K, Chi SH, Dillmann W, Mestril R. Induction of HSP70 in cultured rat neonatal cardiomyocytes by hypoxia and metabolic stress. Circulation. 1993 Jun; 87(6):2023-32. PMID: 8504517.
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    150. Sayen MR, Rohrer DK, Dillmann W. Thyroid hormone response of slow and fast sarcoplasmic reticulum Ca2+ ATPase mRNA in striated muscle. Mol Cell Endocrinol. 1992 Sep; 87(1-3):87-93. PMID: 1446789.
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    151. Villarreal FJ, Dillmann W. Cardiac hypertrophy-induced changes in mRNA levels for TGF-beta 1, fibronectin, and collagen. Am J Physiol. 1992 Jun; 262(6 Pt 2):H1861-6. PMID: 1535758.
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    152. Yuasa R, Eggo MC, Meinkoth J, Dillmann W, Burrow GN. Iodide induces transforming growth factor beta 1 (TGF-beta 1) mRNA in sheep thyroid cells. Thyroid. 1992; 2(2):141-5. PMID: 1525582.
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    153. Mestril R, Dillmann W. Heat shock and adaptive response to ischemia. Trends Cardiovasc Med. 1991 Sep; 1(6):240-4. PMID: 21239302.
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    154. Popovich BK, Sayen MR, Dillmann W. Insulin responsiveness of CK-M and CK-B mRNA in the diabetic rat heart. Am J Physiol. 1991 Sep; 261(3 Pt 1):E377-81. PMID: 1887884.
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    155. Rohrer DK, Hartong R, Dillmann W. Influence of thyroid hormone and retinoic acid on slow sarcoplasmic reticulum Ca2+ ATPase and myosin heavy chain alpha gene expression in cardiac myocytes. Delineation of cis-active DNA elements that confer responsiveness to thyroid hormone but not to retinoic acid. J Biol Chem. 1991 May 05; 266(13):8638-46. PMID: 1827123.
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    156. Maciel LM, Polikar R, Rohrer D, Popovich BK, Dillmann W. Age-induced decreases in the messenger RNA coding for the sarcoplasmic reticulum Ca2(+)-ATPase of the rat heart. Circ Res. 1990 Jul; 67(1):230-4. PMID: 2142022.
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    157. Dillmann W. Biochemical basis of thyroid hormone action in the heart. Am J Med. 1990 Jun; 88(6):626-30. PMID: 2189306.
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    158. Popovich BK, Boheler KR, Dillmann W. Diabetes decreases creatine kinase enzyme activity and mRNA level in the rat heart. Am J Physiol. 1989 Oct; 257(4 Pt 1):E573-7. PMID: 2679131.
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    159. Dillmann W. Diabetes and thyroid-hormone-induced changes in cardiac function and their molecular basis. Annu Rev Med. 1989; 40:373-94. PMID: 2658757.
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    160. Dillmann W, Barrieux A, Shanker R. Influence of thyroid hormone on myosin heavy chain mRNA and other messenger RNAs in the rat heart. Endocr Res. 1989; 15(4):565-77. PMID: 2634555.
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    161. Mehta HB, Popovich BK, Dillmann W. Ischemia induces changes in the level of mRNAs coding for stress protein 71 and creatine kinase M. Circ Res. 1988 Sep; 63(3):512-7. PMID: 3409483.
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    162. Boheler KR, Dillmann W. Cardiac response to pressure overload in the rat: the selective alteration of in vitro directed RNA translation products. Circ Res. 1988 Aug; 63(2):448-56. PMID: 2456165.
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    163. Rohrer D, Dillmann W. Thyroid hormone markedly increases the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart. J Biol Chem. 1988 May 25; 263(15):6941-4. PMID: 2966798.
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    164. Cagliero E, Barrieux A, Lehman C, Dillmann W. Diabetes-induced changes of proteins synthesized by adult cardiac myocytes are partially reversed by insulin. J Mol Cell Cardiol. 1988 May; 20(5):427-34. PMID: 3062185.
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    165. Shanker R, Neeley WE, Dillmann W. Time course of response of individual messenger RNAs in the rat heart to T3. J Mol Cell Cardiol. 1987 Jun; 19(6):595-601. PMID: 3625788.
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    166. Dillmann W, Rohrer D, Popovich B, Barrieux A. Thyroid hormone induced changes in cardiac proteins and mRNAs. Horm Metab Res Suppl. 1987; 17:26-9. PMID: 2895058.
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    167. Dillmann W, Mehta HB, Barrieux A, Guth BD, Neeley WE, Ross J. Ischemia of the dog heart induces the appearance of a cardiac mRNA coding for a protein with migration characteristics similar to heat-shock/stress protein 71. Circ Res. 1986 Jul; 59(1):110-4. PMID: 2426003.
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    168. Barrieux A, Neeley WE, Dillmann W. Diabetes-induced alterations in the translational activity of specific messenger ribonucleic acids isolated from rat hearts. Circ Res. 1985 Aug; 57(2):296-303. PMID: 4017199.
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    169. Dillmann W. Myosin isoenzyme distribution and Ca+2-activated myosin ATPase activity in the rat heart is influenced by fructose feeding and triiodothyronine. Endocrinology. 1985 Jun; 116(6):2160-6. PMID: 3158509.
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    170. Dillmann W. Methyl palmoxirate increases Ca2+-myosin ATPase activity and changes myosin isoenzyme distribution in the diabetic rat heart. Am J Physiol. 1985 May; 248(5 Pt 1):E602-6. PMID: 3158215.
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    171. Dillmann W. Fructose feeding increases Ca++-activated myosin ATPase activity and changes myosin isoenzyme distribution in the diabetic rat heart. Endocrinology. 1984 May; 114(5):1678-85. PMID: 6232127.
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    172. Sogol PB, Hershman JM, Reed AW, Dillmann W. The effects of amiodarone on serum thyroid hormones and hepatic thyroxine 5'-monodeiodination in rats. Endocrinology. 1983 Oct; 113(4):1464-9. PMID: 6617581.
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    173. Dillmann W, Barrieux A, Neeley WE, Contreras P. Influence of thyroid hormone on the in vitro translational activity of specific mRNAs in the rat heart. J Biol Chem. 1983 Jun 25; 258(12):7738-45. PMID: 6863262.
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    174. Dillmann W, Berry S, Alexander NM. A physiological dose of triiodothyronine normalizes cardiac myosin adenosine triphosphatase activity and changes myosin isoenzyme distribution in semistarved rats. Endocrinology. 1983 Jun; 112(6):2081-7. PMID: 6221921.
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    175. Dillmann W. Influence of thyroid hormone administration on myosin ATPase activity and myosin isoenzyme distribution in the heart of diabetic rats. Metabolism. 1982 Mar; 31(3):199-204. PMID: 6210824.
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    176. Dillmann W. Diabetes mellitus induces changes in cardiac myosin of the rat. Diabetes. 1980 Jul; 29(7):579-82. PMID: 6445843.
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    177. Dillmann W, Oppenheimer JH. Glucagon influences the expression of thyroid hormone action: discrepancy between nuclear triiodothyronine receptor number and enzyme responses. Endocrinology. 1979 Jul; 105(1):74-9. PMID: 221207.
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    178. Dillmann W, Mendecki J, Koerner D, Schwartz HL, Oppenheimer JH. Triiodothyronine-stimulated formation of poly(A)-containing nuclear RNA and mRNA in rat liver. Endocrinology. 1978 Feb; 102(2):568-75. PMID: 743979.
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    179. Dillmann W, Schwartz HL, Silva E, Surks MI, Oppenheimer JH. Alpha-amanitin administration results in a temporary inhibition of hepatic enzyme induction by triiodothyronine: further evidence favoring a long-lived mediator of thyroid hormone action. Endocrinology. 1977 Jun; 100(6):1621-7. PMID: 858281.
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    180. Dillmann W, Silva E, Surks MI, Oppenheimer JH. Studies of a thyroid hormone and androgen dependent protein in rat liver cytosol. Acta Endocrinol (Copenh). 1977 Mar; 84(3):548-58. PMID: 190842.
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