Xinlian Zhang

Title(s)Associate Professor In Residence, Herbert Wertheim School of Public Health & Human Longevity Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Longitudinal T-Cell Phenotypic Dynamics During Sustained Antiretroviral Therapy in People With HIV. Open Forum Infect Dis. 2026 Jan; 13(1):ofaf775. Vanpouille C, Wells A, DeGruttola V, Lynch M, Zhang X, Tu XM, Chaillon A, Woodworth B, Gaitan N, Rawlings SA, Landay A, Weber KM, Scully EP, Karn J, Gianella S. PMID: 41536614; PMCID: PMC12798725.
      View in: PubMed   Mentions:
    2. An effective short form of the 20-item University of California Los Angeles Loneliness Scale version 3: item response theory and network psychometrics. Gen Psychiatr. 2025; 38(4):e102055. Liu J, Chen M, Wu H, Cai H, Tu S, Lee E, Zhang X. PMID: 40667491; PMCID: PMC12258266.
      View in: PubMed   Mentions:
    3. Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease. Cell Host Microbe. 2025 Jun 11; 33(6):957-972.e6. Yang Y, Duan Y, Lang S, Fondevila MF, Schöler D, Harberts A, Cabré N, Chen S, Shao Y, Vervier K, Miyamoto Y, Zhang X, Chu H, Yang L, Tan C, Eckmann L, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Stärkel P, Lawley TD, Schnabl B. PMID: 40441146; PMCID: PMC12162233.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    4. Mothers Inspiring Healthy Actions (MIHA) program: A randomized control trial testing obesity treatment for mother-daughter dyads. Contemp Clin Trials. 2025 07; 154:107946. Marquez B, Zhang X, Lebensohn-Chialvo F, Butte KT, Arredondo E, Allison M. PMID: 40383370; PMCID: PMC12150675.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease. J Clin Invest. 2025 Jul 01; 135(13). Cabré N, Fondevila MF, Wei W, Yamazaki T, Tonetti FR, Eguileor A, Garcia-Carbonell R, Meijnikman AS, Miyamoto Y, Mayo S, Wang Y, Zhang X, Trimbuch T, Lehnardt S, Eckmann L, Fouts DE, Llorente C, Tsukamoto H, Stärkel P, Schnabl B. PMID: 40359032; PMCID: PMC12208555.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis. Gut. 2024 12 10; 74(1):103-115. Kreimeyer H, Gonzalez CG, Fondevila MF, Hsu CL, Hartmann P, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Investigators A, Gonzalez DJ, Schnabl B. PMID: 39033024; PMCID: PMC11631684.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. Cytokine trajectory over time in men and women with HIV on long-term antiretroviral therapy. AIDS. 2025 Jan 01; 39(1):1-10. Vanpouille C, Wells A, DeGruttola V, Lynch M, Zhang X, Fitzgerald W, Tu X, Chaillon A, Landay A, Weber K, Scully E, Karn J, Gianella S. PMID: 39639719; PMCID: PMC11631044.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. A doubly robust estimator for the Mann Whitney Wilcoxon rank sum test when applied for causal inference in observational studies. J Appl Stat. 2024; 51(16):3267-3291. Chen R, Lin T, Liu L, Liu J, Chen R, Zou J, Liu C, Natarajan L, Tang W, Zhang X, Tu X. PMID: 39628859; PMCID: PMC11610351.
      View in: PubMed   Mentions:
    9. Body image and physical activity in Latinas. J Behav Med. 2024 06; 47(3):531-536. Marquez B, Zhang X, Huang X, Mendoza-Vasconez A, Benitez T, Marcus B. PMID: 38393444; PMCID: PMC11234904.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis. Hepatology. 2024 08 01; 80(2):403-417. Yamazaki T, Kouno T, Hsu CL, Hartmann P, Mayo S, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Schnabl B, AlcHepNet Investigators. PMID: 38377466; PMCID: PMC11268475.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    11. Fungal signature differentiates alcohol-associated liver disease from nonalcoholic fatty liver disease. Gut Microbes. 2024 Jan-Dec; 16(1):2307586. Viebahn G, Hartmann P, Lang S, Demir M, Zhang X, Fouts DE, Stärkel P, Schnabl B. PMID: 38298161; PMCID: PMC10841010.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    12. Single-cell RNA sequencing reveals common and unique gene expression profiles in primary CD4+ T cells latently infected with HIV under different conditions. Front Cell Infect Microbiol. 2023; 13:1286168. Zhang X, Qazi AA, Deshmukh S, Lobato Ventura R, Mukim A, Beliakova-Bethell N. PMID: 38156317; PMCID: PMC10754520.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nat Genet. 2023 12; 55(12):2189-2199. Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, Adam M, Morgan L, Wani S, Tiwari A, Guccione C, Lin Y, Dutta A, Lo YY, Juarez E, Robinson JT, Korshunov A, Michaels JA, Cho YJ, Malicki DM, Coufal NG, Levy ML, Hobbs C, Scheuermann RH, Crawford JR, Pomeroy SL, Rich JN, Zhang X, Chang HY, Dixon JR, Bagchi A, Deshpande AJ, Carter H, Fraenkel E, Mischel PS, Wechsler-Reya RJ, Bafna V, Mesirov JP, Chavez L. PMID: 37945900; PMCID: PMC10703696.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    14. A New Paradigm for High-dimensional Data: Distance-Based Semiparametric Feature Aggregation Framework via Between-Subject Attributes. Scand Stat Theory Appl. 2024 Jun; 51(2):672-696. Liu J, Zhang X, Lin T, Chen R, Zhong Y, Chen T, Wu T, Liu C, Huang A, Nguyen TT, Lee EE, Jeste DV, Tu XM. PMID: 39101047; PMCID: PMC11296665.
      View in: PubMed   Mentions:
    15. The fecal mycobiome in non-alcoholic fatty liver disease. J Hepatol. 2022 04; 76(4):788-799. Demir M, Lang S, Hartmann P, Duan Y, Martin A, Miyamoto Y, Bondareva M, Zhang X, Wang Y, Kasper P, Bang C, Roderburg C, Tacke F, Steffen HM, Goeser T, Kruglov A, Eckmann L, Stärkel P, Fouts DE, Schnabl B. PMID: 34896404; PMCID: PMC8981795.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimals
    16. Dynamic Changes of the Fungal Microbiome in Alcohol Use Disorder. Front Physiol. 2021; 12:699253. Hartmann P, Lang S, Zeng S, Duan Y, Zhang X, Wang Y, Bondareva M, Kruglov A, Fouts DE, Stärkel P, Schnabl B. PMID: 34349667; PMCID: PMC8327211.
      View in: PubMed   Mentions: 52  
    17. Relation of prior statin and anti-hypertensive use to severity of disease among patients hospitalized with COVID-19: Findings from the American Heart Association's COVID-19 Cardiovascular Disease Registry. PLoS One. 2021; 16(7):e0254635. Daniels LB, Ren J, Kumar K, Bui QM, Zhang J, Zhang X, Sawan MA, Eisen H, Longhurst CA, Messer K. PMID: 34264974; PMCID: PMC8281996.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    18. A semiparametric model for between-subject attributes: Applications to beta-diversity of microbiome data. Biometrics. 2022 09; 78(3):950-962. Liu J, Zhang X, Chen T, Wu T, Lin T, Jiang L, Lang S, Liu L, Natarajan L, Tu JX, Kosciolek T, Morton J, Nguyen TT, Schnabl B, Knight R, Feng C, Zhong Y, Tu XM. PMID: 34010477; PMCID: PMC8602427.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease. Liver Int. 2021 07; 41(7):1576-1591. Lang S, Martin A, Zhang X, Farowski F, Wisplinghoff H, J G T Vehreschild M, Krawczyk M, Nowag A, Kretzschmar A, Scholz C, Kasper P, Roderburg C, Mohr R, Lammert F, Tacke F, Schnabl B, Goeser T, Steffen HM, Demir M. PMID: 33896117; PMCID: PMC8947846.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    20. Association of Loneliness and Wisdom With Gut Microbial Diversity and Composition: An Exploratory Study. Front Psychiatry. 2021; 12:648475. Nguyen TT, Zhang X, Wu TC, Liu J, Le C, Tu XM, Knight R, Jeste DV. PMID: 33841213; PMCID: PMC8029068.
      View in: PubMed   Mentions: 18  
    21. Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3. J Biol Chem. 2021 Jan-Jun; 296:100575. Granados JC, Richelle A, Gutierrez JM, Zhang P, Zhang X, Bhatnagar V, Lewis NE, Nigam SK. PMID: 33757768; PMCID: PMC8102410.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    22. Dicer-like proteins influence Arabidopsis root microbiota independent of RNA-directed DNA methylation. Microbiome. 2021 02 26; 9(1):57. Kaushal R, Peng L, Singh SK, Zhang M, Zhang X, Vílchez JI, Wang Z, He D, Yang Y, Lv S, Xu Z, Morcillo RJL, Wang W, Huang W, Paré PW, Song CP, Zhu JK, Liu R, Zhong W, Ma P, Zhang H. PMID: 33637135; PMCID: PMC7913254.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    23. Fungi-Bacteria Correlation in Alcoholic Hepatitis Patients. Toxins (Basel). 2021 02 14; 13(2). Gao B, Zhang X, Schnabl B. PMID: 33672887; PMCID: PMC7917833.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    24. Intestinal Virome in Patients With Alcoholic Hepatitis. Hepatology. 2020 12; 72(6):2182-2196. Jiang L, Lang S, Duan Y, Zhang X, Gao B, Chopyk J, Schwanemann LK, Ventura-Cots M, Bataller R, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Ho SB, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Kisseleva T, Brenner DA, Tu XM, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 32654263; PMCID: PMC8159727.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    25. Rods Contribute to Visual Behavior in Larval Zebrafish. Invest Ophthalmol Vis Sci. 2020 10 01; 61(12):11. Venkatraman P, Mills-Henry I, Padmanabhan KR, Pascuzzi P, Hassan M, Zhang J, Zhang X, Ma P, Pang CP, Dowling JE, Zhang M, Leung YF. PMID: 33049059; PMCID: PMC7571310.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    26. Strength of immune selection in tumors varies with sex and age. Nat Commun. 2020 08 17; 11(1):4128. Castro A, Pyke RM, Zhang X, Thompson WK, Day CP, Alexandrov LB, Zanetti M, Carter H. PMID: 32807809; PMCID: PMC7431859.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    27. Changes in the fecal bacterial microbiota associated with disease severity in alcoholic hepatitis patients. Gut Microbes. 2020 11 09; 12(1):1785251. Lang S, Fairfied B, Gao B, Duan Y, Zhang X, Fouts DE, Schnabl B. PMID: 32684075; PMCID: PMC7524371.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    28. Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease. Gastroenterology. 2020 11; 159(5):1839-1852. Lang S, Demir M, Martin A, Jiang L, Zhang X, Duan Y, Gao B, Wisplinghoff H, Kasper P, Roderburg C, Tacke F, Steffen HM, Goeser T, Abraldes JG, Tu XM, Loomba R, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 32652145; PMCID: PMC8404510.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    29. METHYLTRANSFERASE1 and Ripening Modulate Vivipary during Tomato Fruit Development. Plant Physiol. 2020 08; 183(4):1883-1897. Yao M, Chen W, Kong J, Zhang X, Shi N, Zhong S, Ma P, Gallusci P, Jackson S, Liu Y, Hong Y. PMID: 32503901; PMCID: PMC7401104.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    30. Foxtail mosaic virus-induced flowering assays in monocot crops. J Exp Bot. 2020 05 30; 71(10):3012-3023. Yuan C, Li H, Qin C, Zhang X, Chen Q, Zhang P, Xu X, He M, Zhang X, Tör M, Xue D, Wang H, Jackson S, He Y, Liu Y, Shi N, Hong Y. PMID: 32061090.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    31. Molecular and functional characterization of the SBP-box transcription factor SPL-CNR in tomato fruit ripening and cell death. J Exp Bot. 2020 05 30; 71(10):2995-3011. Lai T, Wang X, Ye B, Jin M, Chen W, Wang Y, Zhou Y, Blanks AM, Gu M, Zhang P, Zhang X, Li C, Wang H, Liu Y, Gallusci P, Tör M, Hong Y. PMID: 32016417; PMCID: PMC7260717.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    32. MHC-I genotype and tumor mutational burden predict response to immunotherapy. Genome Med. 2020 05 19; 12(1):45. Goodman AM, Castro A, Pyke RM, Okamura R, Kato S, Riviere P, Frampton G, Sokol E, Zhang X, Ball ED, Carter H, Kurzrock R. PMID: 32430031; PMCID: PMC7236948.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    33. An RNAi suppressor activates in planta virus-mediated gene editing. Funct Integr Genomics. 2020 Jul; 20(4):471-477. Zhang X, Kang L, Zhang Q, Meng Q, Pan Y, Yu Z, Shi N, Jackson S, Zhang X, Wang H, Tor M, Hong Y. PMID: 31848794.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    34. Normalization of large-scale behavioural data collected from zebrafish. PLoS One. 2019; 14(2):e0212234. Xie R, Zhang M, Venkatraman P, Zhang X, Zhang G, Carmer R, Kantola SA, Pang CP, Ma P, Zhang M, Zhong W, Leung YF. PMID: 30768618; PMCID: PMC6377122.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    35. Mini review: Revisiting mobile RNA silencing in plants. Plant Sci. 2019 Jan; 278:113-117. Zhang X, Lai T, Zhang P, Zhang X, Yuan C, Jin Z, Li H, Yu Z, Qin C, Tör M, Ma P, Cheng Q, Hong Y. PMID: 30471724; PMCID: PMC6556431.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    36. SIRT5 as a biomarker for response to anthracycline-taxane-based neoadjuvant chemotherapy in triple-negative breast cancer. Oncol Rep. 2018 May; 39(5):2315-2323. Xu L, Che X, Wu Y, Song N, Shi S, Wang S, Li C, Zhang L, Zhang X, Qu X, Teng Y. PMID: 29565454.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsCTClinical Trials
    37. Statistical Leveraging Methods in Big Data. Handbook of Big Data Analytics. 2018; 51-74. Zhang X., Xie R., Ma P. View Publication.
    38. Expression profiling of the retina of pde6c, a zebrafish model of retinal degeneration. Sci Data. 2017 12 12; 4:170182. Zhang L, Zhang X, Zhang G, Pang CP, Leung YF, Zhang M, Zhong W. PMID: 29231925; PMCID: PMC5726315.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    39. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Dev Cell. 2017 08 07; 42(3):241-255.e6. Akay A, Di Domenico T, Suen KM, Nabih A, Parada GE, Larance M, Medhi R, Berkyurek AC, Zhang X, Wedeles CJ, Rudolph KLM, Engelhardt J, Hemberg M, Ma P, Lamond AI, Claycomb JM, Miska EA. PMID: 28787591; PMCID: PMC5554785.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
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