Zea Borok

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of Cape Town, South AfricaM.B., Ch.B.1979University, Medical School
    Groote Schuur Hospital, Cape Town, South Africa1981Internship
    Montefiore Hospital, Pittsburgh, PA1983Internship
    Montefiore Hospital, Pittsburgh, PAMD1985Internal Medicine Residency
    College of Physicians & Surgeons of Columbia University , New York, NY1981Thrombosis Fellowship
    Presbyterian-University Hospital , Pittsburgh, PA1987Critical Care Medicine Fellowship
    National Institutes of Health, Pulmonary Branch , Bethesda, MD1990Pulmonary Medicine
    Collapse Awards and Honors
    2021Southern California Superdoctors
    Drexel University2018  - 2019Leadership in Academic Medicine Program
    2017American Thoracic Society Fellow
    2017  - 2024NHLBI R35 Outstanding Investigator Award
    American Thoracic Society 2017Elizabeth Rich Award
    Western Society for Clinical Investigation 2017Mayo Soley Award
    2014Elected to Association of American Physicians

    Collapse Overview 
    Collapse Overview
    Zea Borok, MD is the Helen M. Ranney Professor and Chair of the Department of Medicine.

    Borok was previously the Ralph Edgington Chair in Medicine, Division Chief of Pulmonary and Critical Care Medicine and Hastings Professor of Medicine and Biochemistry and Molecular Medicine at the Keck School of Medicine at the University of Southern California (USC) in Los Angeles, which she joined in 1990 as an instructor. At USC, Borok led expansion of research efforts and creation of clinical programs of excellence, such as the Center for Advanced Lung Disease, Pulmonary Hypertension Program, Sleep Center and the Interventional Pulmonary Program.

    Throughout her career, Borok said she has emphasized mentoring students, trainees and faculty, having directed more than 30 individuals. She said she is particularly aware of the challenges facing female faculty members and focuses her time mentoring and sponsoring other female scientists seeking career advancement within their fields of research.

    Collapse Research 
    Collapse Research Activities and Funding
    Beyond the barrier: alveolar epithelial cell biology in health and disease
    NIH R35HL135747Jul 1, 2017 - Jun 30, 2024
    Role: Principal Investigator
    Role of claudin 18 in regulation of lung stem/progenitor cell homeostasis
    NIH R01HL126877Feb 1, 2016 - Dec 31, 2019
    Role: Principal Investigator
    Mechanisms of beta-catenin signaling in alveolar epithelial cell differentiation
    NIH R01HL112638Jul 1, 2013 - Jun 30, 2017
    Role: Principal Investigator
    Epigenetic profiling of human alveolar epithelial cells in health and disease
    NIH R01HL114094Sep 23, 2011 - Jun 30, 2017
    Role: Co-Investigator
    Epigenetic regulation of AEC Plasticity and epithelial-mesenchymal transition
    NIH P30HL101258Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Alveolar epithelial-mesenchymal transition (EMT) in pulmonary fibrosis
    NIH R01HL089445Jul 1, 2008 - May 31, 2013
    Role: Principal Investigator
    Molecular programming of AEC differentiation: role of forkhead factors
    NIH R37HL062569Aug 15, 2000 - Dec 31, 2015
    Role: Principal Investigator