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Jane Kim

Title(s)Assistant Clinical Professor, Pediatrics
SchoolHealth Sciences
Phone858-246-2022
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    Collapse Research 
    Collapse Research Activities and Funding
    Continuous Glucose Monitoring in Infants
    Dexcom Inc. Jun 1, 2020 - May 31, 2022
    Role: Principal Investigator
    Linking the Gut Microbiome to Metabolism in Obese Children with Type 1 Diabetes
    UCSD CTRI Pilot Project Award Apr 1, 2017 - Mar 31, 2018
    Urinary Metabolomic Profiling in Children and Adults with Type 2 Diabetes
    American Diabetes Association Innovation Award 1-14-IN-27Jan 1, 2014 - Dec 31, 2016
    Role: Principal Investigator
    Epigenetics of Obesity and Insulin Resistance
    NIH/NIDDK R03DK097412Dec 1, 2012 - Nov 30, 2015
    Role: Principal Investigator
    Studies of Fox01 in Insulin Resistance and its interaction with PPARgamma
    NIH/NIDDK K08DK075479Sep 20, 2007 - Aug 31, 2013
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chen K, Jih A, Osborn O, Kavaler ST, Fu W, Sasik R, Saito R, Kim JJ. Distinct gene signatures predict insulin resistance in young mice with high fat diet-induced obesity. Physiol Genomics. 2018 03 01; 50(3):144-157. PMID: 29341863.
      View in: PubMed
    2. Soontornniyomkij V, Kesby JP, Soontornniyomkij B, Kim JJ, Kisseleva T, Achim CL, Semenova S, Jeste DV. Age and High-Fat Diet Effects on Glutamine Synthetase Immunoreactivity in Liver and Hippocampus and Recognition Memory in Mice. Curr Aging Sci. 2016; 9(4):301-309. PMID: 27071478.
      View in: PubMed
    3. Kim JJ, Tosteson AN, Zauber AG, Sprague BL, Stout NK, Alagoz O, Trentham-Dietz A, Armstrong K, Pruitt SL, Rutter CM. Cancer Models and Real-world Data: Better Together. J Natl Cancer Inst. 2016 Feb; 108(2). PMID: 26538628.
      View in: PubMed
    4. Kesby JP, Kim JJ, Scadeng M, Woods G, Kado DM, Olefsky JM, Jeste DV, Achim CL, Semenova S. Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet. PLoS One. 2015; 10(10):e0140034. PMID: 26448649.
      View in: PubMed
    5. Chen K, Jih A, Kavaler ST, Lagakos WS, Oh D, Watkins SM, Kim JJ. Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance. Am J Physiol Endocrinol Metab. 2015 Aug 01; 309(3):E293-301. PMID: 26058862.
      View in: PubMed
    6. Beaber EF, Kim JJ, Schapira MM, Tosteson AN, Zauber AG, Geiger AM, Kamineni A, Weaver DL, Tiro JA. Unifying screening processes within the PROSPR consortium: a conceptual model for breast, cervical, and colorectal cancer screening. J Natl Cancer Inst. 2015 Jun; 107(6):djv120. PMID: 25957378.
      View in: PubMed
    7. Lee YS, Morinaga H, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky J. The fractalkine/CX3CR1 system regulates ß cell function and insulin secretion. Cell. 2013 Apr 11; 153(2):413-25. PMID: 23582329.
      View in: PubMed
    8. Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Lazarowski E, Olefsky JM, Kim JJ. GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity. J Immunol. 2012 Aug 15; 189(4):1992-9. PMID: 22778393.
      View in: PubMed
    9. Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. J Clin Invest. 2012 Jul; 122(7):2444-53. PMID: 22653059.
      View in: PubMed
    10. Kim JJ, Fan W, Olefsky JM. Putting the brakes on FOXO1 in fat. EMBO J. 2012 May 16; 31(10):2240-1. PMID: 22510885.
      View in: PubMed
    11. Kavaler S, Morinaga H, Jih A, Fan W, Hedlund M, Varki A, Kim JJ. Pancreatic beta-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency. FASEB J. 2011 Jun; 25(6):1887-93. PMID: 21350118.
      View in: PubMed
    12. Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J. 2010 Dec 15; 29(24):4223-36. PMID: 21045807.
      View in: PubMed
    13. Kim JJ, Sears DD. TLR4 and Insulin Resistance. Gastroenterol Res Pract. 2010; 2010. PMID: 20814545.
      View in: PubMed
    14. Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes. 2009 Jun; 58(6):1275-82. PMID: 19289458.
      View in: PubMed
    15. Fan W, Imamura T, Sonoda N, Sears DD, Patsouris D, Kim JJ, Olefsky JM. FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. J Biol Chem. 2009 May 01; 284(18):12188-97. PMID: 19246449.
      View in: PubMed
    16. Kim JJ, Kido Y, Scherer PE, White MF, Accili D. Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1694-701. PMID: 17299086.
      View in: PubMed
    17. Hosch SE, Olefsky JM, Kim JJ. APPLied mechanics: uncovering how adiponectin modulates insulin action. Cell Metab. 2006 Jul; 4(1):5-6. PMID: 16814726.
      View in: PubMed
    18. Kim JJ, Accili D. Signalling through IGF-I and insulin receptors: where is the specificity? Growth Horm IGF Res. 2002 Apr; 12(2):84-90. PMID: 12175645.
      View in: PubMed