Jon Gangoiti

Title(s)	CLIN RSCH SUPV 2, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Use of an oversized AAV8 vector for CPS1 deficiency results in long-term survival and ammonia control. Mol Ther Nucleic Acids. 2025 Mar 11; 36(1):102470. Diep T, Zhou W, Reyes RE, Nitzahn M, Day IL, Makris G, Lueptow L, Zhuravka I, Bakshi S, Gangoiti J, Padaon H, Li Y, Barshop BA, Haberle J, Lipshutz GS. PMID: 40083646; PMCID: PMC11905892.

View in: PubMed Mentions: 1
Changes in Expression of DNA-Methyltransferase and Cannabinoid Receptor mRNAs in Blood Lymphocytes After Acute Cannabis Smoking. Front Psychiatry. 2022; 13:887700. Smith RC, Sershen H, Janowsky DS, Lajtha A, Grieco M, Gangoiti JA, Gertsman I, Johnson WS, Marcotte TD, Davis JM. PMID: 35859599; PMCID: PMC9290435.

View in: PubMed Mentions: 3
Pregnancy and Breastfeeding in Nephropathic Cystinosis With Native Kidneys. Kidney Int Rep. 2022 Jul; 7(7):1716-1719. Chan L, Wichart J, Kiang T, Khurana R, Gangoiti JA, Barshop BA, Midgley J. PMID: 35812296; PMCID: PMC9263244.

View in: PubMed Mentions: 1
Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice. J Clin Invest. 2021 11 01; 131(21). Mishra S, Sadagopan N, Dunkerly-Eyring B, Rodriguez S, Sarver DC, Ceddia RP, Murphy SA, Knutsdottir H, Jani VP, Ashok D, Oeing CU, O'Rourke B, Gangoiti JA, Sears DD, Wong GW, Collins S, Kass DA. PMID: 34618683; PMCID: PMC8553561.

View in: PubMed Mentions: 12 Fields:
Med Medicine (General)
Translation:Animals Cells
Tumor metabolism and neurocognition in CNS lymphoma. Neuro Oncol. 2021 10 01; 23(10):1668-1679. Geng H, Tsang M, Subbaraj L, Cleveland J, Chen L, Lu M, Sharma J, Vigneron DB, Kurhanewicz J, LaFontaine M, Luks T, Barshop BA, Gangoiti J, Villanueva-Meyer JE, Rubenstein JL. PMID: 33625503; PMCID: PMC8485453.

View in: PubMed Mentions: 6 Fields:
Neo Neoplasms Neu Neurology
Translation:Humans
Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children. J Pediatr Gastroenterol Nutr. 2021 04 01; 72(4):e90-e96. Sawh MC, Wallace M, Shapiro E, Goyal NP, Newton KP, Yu EL, Bross C, Durelle J, Knott C, Gangoiti JA, Barshop BA, Gengatharan JM, Meurs N, Schlein A, Middleton MS, Sirlin CB, Metallo CM, Schwimmer JB. PMID: 33399331; PMCID: PMC8842839.

View in: PubMed Mentions: 11 Fields:
Gas Gastroenterology Nut Nutritional Sciences Ped Pediatrics
Translation:Humans
Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. J Antimicrob Chemother. 2020 10 01; 75(10):2925-2932. Probst A, Häberli C, Siegel D, Huang J, Vigneron S, Ta AP, Skinner DE, El-Sakkary N, Momper JD, Gangoiti J, Dong Y, Vennerstrom JL, Charman SA, Caffrey CR, Keiser J. PMID: 32617557; PMCID: PMC7556815.

View in: PubMed Mentions: 1 Fields:
Ant Anti-Infective Agents
Translation:Animals
Cardiac tissue citric acid cycle intermediates in exercised very long-chain acyl-CoA dehydrogenase-deficient mice fed triheptanoin or medium-chain triglyceride. J Inherit Metab Dis. 2020 11; 43(6):1232-1242. Gaston G, Gangoiti JA, Winn S, Chan B, Barshop BA, Harding CO, Gillingham MB. PMID: 33448436.

View in: PubMed Mentions: 5 Fields:
Met Metabolism
Translation:Animals Cells
Identification of pathognomonic purine synthesis biomarkers by metabolomic profiling of adolescents with obesity and type 2 diabetes. PLoS One. 2020; 15(6):e0234970. Concepcion J, Chen K, Saito R, Gangoiti J, Mendez E, Nikita ME, Barshop BA, Natarajan L, Sharma K, Kim JJ. PMID: 32589682; PMCID: PMC7319336.

View in: PubMed Mentions: 16 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma. Blood Adv. 2018 07 10; 2(13):1595-1607. Rubenstein JL, Geng H, Fraser EJ, Formaker P, Chen L, Sharma J, Killea P, Choi K, Ventura J, Kurhanewicz J, Lowell C, Hwang J, Treseler P, Sneed PK, Li J, Wang X, Chen N, Gangoiti J, Munster PN, Damato B. PMID: 29986852; PMCID: PMC6039666.

View in: PubMed Mentions: 72 Fields:
Hem Hematology
Translation:Humans CTClinical Trials
Inhibition of HDAC8 and HDAC9 by microbial short-chain fatty acids breaks immune tolerance of the epidermis to TLR ligands. Sci Immunol. 2016 Oct 28; 1(4). Sanford JA, Zhang LJ, Williams MR, Gangoiti JA, Huang CM, Gallo RL. PMID: 28783689.

View in: PubMed Mentions: 68 Fields:
All Allergy and Immunology
Hereditary Orotic Aciduria and the Excretion of Orotidine. Neuropediatrics. 2016 Dec; 47(6):408-409. Nyhan WL, Gangoiti JA. PMID: 27574833.

View in: PubMed Mentions: Fields:
Neu Neurology Ped Pediatrics
Translation:Humans
The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome. J Microb Biochem Technol. 2016 Aug; 8(4):259-265. Kao MS, Wang Y, Marito S, Huang S, Lin WZ, Gangoiti JA, Barshop BA, Hyun C, Lee WR, Sanford JA, Gallo RL, Ran Y, Chen WT, Huang CJ, Hsieh MF, Huang CM. PMID: 28111598; PMCID: PMC5243119.

View in: PubMed Mentions: 6
Diagnosis and Monitoring of Cystinosis Using Immunomagnetically Purified Granulocytes. Clin Chem. 2016 05; 62(5):766-72. Gertsman I, Johnson WS, Nishikawa C, Gangoiti JA, Holmes B, Barshop BA. PMID: 26980209.

View in: PubMed Mentions: 7 Fields:
Che Chemistry
Translation:Humans Cells
Metabolic Effects of Increasing Doses of Nitisinone in the Treatment of Alkaptonuria. JIMD Rep. 2015; 24:13-20. Gertsman I, Barshop BA, Panyard-Davis J, Gangoiti JA, Nyhan WL. PMID: 25665838; PMCID: PMC4582031.

View in: PubMed Mentions: 9
Perturbations of tyrosine metabolism promote the indolepyruvate pathway via tryptophan in host and microbiome. Mol Genet Metab. 2015 Mar; 114(3):431-7. Gertsman I, Gangoiti JA, Nyhan WL, Barshop BA. PMID: 25680927.

View in: PubMed Mentions: 24 Fields:
Bio Biochemistry Met Metabolism Mol Molecular Biology
Translation:Humans Cells
Validation of a dual LC-HRMS platform for clinical metabolic diagnosis in serum, bridging quantitative analysis and untargeted metabolomics. Metabolomics. 2014 Apr 04; 10(2):312-323. Gertsman I, Gangoiti JA, Barshop BA. PMID: 25411574; PMCID: PMC4234038.

View in: PubMed Mentions: 21 Fields:
Met Metabolism
A model-driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K-12 MG1655 that is biochemically and thermodynamically consistent. Biotechnol Bioeng. 2014 Apr; 111(4):803-15. McCloskey D, Gangoiti JA, King ZA, Naviaux RK, Barshop BA, Palsson BO, Feist AM. PMID: 24249002.

View in: PubMed Mentions: 26 Fields:
Bio Biomedical Engineering Bio Biotechnology
Translation:Cells
Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol. 2013 Nov; 24(11):1901-12. Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK. PMID: 23949796; PMCID: PMC3810086.

View in: PubMed Mentions: 284 Fields:
Nep Nephrology
Translation:Humans
Cysteamine modulates oxidative stress and blocks myofibroblast activity in CKD. J Am Soc Nephrol. 2014 Jan; 25(1):43-54. Okamura DM, Bahrami NM, Ren S, Pasichnyk K, Williams JM, Gangoiti JA, Lopez-Guisa JM, Yamaguchi I, Barshop BA, Duffield JS, Eddy AA. PMID: 24009239; PMCID: PMC3871767.

View in: PubMed Mentions: 30 Fields:
Nep Nephrology
Translation:Animals Cells
Pharmacokinetics of cysteamine bitartrate following intraduodenal delivery. Fundam Clin Pharmacol. 2014 Apr; 28(2):136-43. Dohil R, Cabrera BL, Gangoiti JA, Barshop BA, Rioux P. PMID: 23113697.

View in: PubMed Mentions: 9 Fields:
Pha Pharmacology
Translation:Animals
The Effect of Food on Cysteamine Bitartrate Absorption in Healthy Participants. Clin Pharmacol Drug Dev. 2012 Oct; 1(4):170-4. Dohil R, Cabrera BL, Gangoiti J, Rioux P. PMID: 27121459.

View in: PubMed Mentions: 3 Fields:
Dru Drug Therapy Pha Pharmacology
The role of DMQ(9) in the long-lived mutant clk-1. Mech Ageing Dev. 2011 Jun-Jul; 132(6-7):331-9. Yang YY, Vasta V, Hahn S, Gangoiti JA, Opheim E, Sedensky MM, Morgan PG. PMID: 21745495; PMCID: PMC3156029.

View in: PubMed Mentions: 17 Fields:
Ger Geriatrics
Pharmacokinetics of enteric-coated cysteamine bitartrate in healthy adults: a pilot study. Br J Clin Pharmacol. 2010 Sep; 70(3):376-82. Gangoiti JA, Fidler M, Cabrera BL, Schneider JA, Barshop BA, Dohil R. PMID: 20716238; PMCID: PMC2949910.

View in: PubMed Mentions: 13 Fields:
Pha Pharmacology
Translation:Humans
Long-term treatment of cystinosis in children with twice-daily cysteamine. J Pediatr. 2010 May; 156(5):823-7. Dohil R, Gangoiti JA, Cabrera BL, Fidler M, Schneider JA, Barshop BA. PMID: 20138296.

View in: PubMed Mentions: 15 Fields:
Ped Pediatrics
Translation:Humans Cells
Twice-daily cysteamine bitartrate therapy for children with cystinosis. J Pediatr. 2010 Jan; 156(1):71-75.e1-3. Dohil R, Fidler M, Gangoiti JA, Kaskel F, Schneider JA, Barshop BA. PMID: 19775699.

View in: PubMed Mentions: 25 Fields:
Ped Pediatrics
Translation:Humans Cells
Time before isolating cystinotic leukocytes affects reliability of cystine determination. Pediatr Nephrol. 2009 Dec; 24(12):2465-6. Fidler MC, Gangoiti JA, Schneider JA, Barshop BA. PMID: 19396469; PMCID: PMC2770136.

View in: PubMed Mentions: Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans Cells
The effect of different ubiquinones on lifespan in Caenorhabditis elegans. Mech Ageing Dev. 2009 Jun; 130(6):370-6. Yang YY, Gangoiti JA, Sedensky MM, Morgan PG. PMID: 19428456; PMCID: PMC2684812.

View in: PubMed Mentions: 21 Fields:
Ger Geriatrics
Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol. 2008 Sep; 19(9):1732-40. Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. PMID: 18508962; PMCID: PMC2518443.

View in: PubMed Mentions: 36 Fields:
Nep Nephrology
Translation:Animals Cells
Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics. 2008 Apr 22; 33(2):180-92. Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. PMID: 18270321; PMCID: PMC3016923.

View in: PubMed Mentions: 92 Fields:
Mol Molecular Biology
Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin Chem. 2007 Dec; 53(12):2169-76. Wikoff WR, Gangoiti JA, Barshop BA, Siuzdak G. PMID: 17951291.

View in: PubMed Mentions: 61 Fields:
Che Chemistry
Translation:Humans
Analysis of coenzyme Q in human blood and tissues. Mitochondrion. 2007 Jun; 7 Suppl:S89-93. Barshop BA, Gangoiti JA. PMID: 17485249.

View in: PubMed Mentions: 17 Fields:
Cel Cell Biology
Translation:Humans Cells
Pharmacokinetics of cysteamine bitartrate following gastrointestinal infusion. Br J Clin Pharmacol. 2007 Jan; 63(1):36-40. Fidler MC, Barshop BA, Gangoiti JA, Deutsch R, Martin M, Schneider JA, Dohil R. PMID: 17229040; PMCID: PMC2000721.

View in: PubMed Mentions: 11 Fields:
Pha Pharmacology
Translation:Humans
Understanding intestinal cysteamine bitartrate absorption. J Pediatr. 2006 Jun; 148(6):764-9. Dohil R, Fidler M, Barshop BA, Gangoiti J, Deutsch R, Martin M, Schneider JA. PMID: 16769383.

View in: PubMed Mentions: 16 Fields:
Ped Pediatrics
Translation:Humans Cells
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem. 2006 Feb 24; 281(8):5072-83. Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. PMID: 16354673.

View in: PubMed Mentions: 92 Fields:
Bio Biochemistry
Translation:Animals Cells