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Adriana Tremoulet

Title(s)Professor Of Clinical, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0641
La Jolla CA 92093
Phone858-246-0012
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego, San Diego, CAMAS06/2009Master in Clinical Research
    University of California, San Diego, San Diego, CA06/2006Peds ID Fellowship
    Cedars Sinai Medical Center, Los Angeles, CA06/2003Pediatric Residency
    University of California, Los Angeles, Los Angeles, CAMD06/2000Medicine
    Harvard University, Boston, MAAB06/1995Biochemistry

    Collapse Overview 
    Collapse Overview
    Dr. Adriana (Adri) Tremoulet is an Associate Professor of Clinical Pediatrics in the Division of Host-Microbe Systems and Therapeutics in the Department of Pediatrics at UC San Diego, specializing in pediatric infectious diseases and clinical pharmacology. She serves as the Associate Director of the Kawasaki Disease (KD) Research Center at UC San Diego, caring for nearly 1700 children with KD in San Diego County and an additional 100 children annually hospitalized at Rady Children’s Hospital San Diego with KD. The primary focus of her research is repurposing therapeutics in Phase I through III clinical trials for inflammatory and infectious disorders. She has a passion for pediatric pharmacology and serves as the co-principal investigator of the NIH-funded UC San Diego Research Program in Developmental Pharmacology (RPDP) as well as co-Director of the UC San Diego Department of Pediatric Clinical Pharmacology Training Program and Altman Clinical Trials Research Institute KL2 progam. She also serves as the UC San Diego site PI for the NICHD funded Pediatric Trials Network. She is currently leading Phase I/IIa clinical trials of atorvastatin and anakinra in children with KD and coronary artery damage. As a native Spanish speaker, she has established the KD Latin American Network that collaborates in 20 Latin American countries in the collection of clinical and phenotypic data of KD patients to better understand the impact of KD in this region of the world.

    Collapse Research 
    Collapse Research Activities and Funding
    Refining an Innovative Phase III Trial of Adjunctive Therapy in Acute Kawasaki Disease with Coronary Artery Aneurysms
    NIH/NHLBI U34HL148673Aug 15, 2019 - Jul 31, 2020
    Role: Principal Investigator
    Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease
    NIH/NHLBI R01HL140898Jan 1, 2018 - Nov 30, 2022
    Role: Co-Principal Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH/NICHD U54HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Developing Pediatric Clinical Pharmacologists for the Advancement of Therapeutics
    NIH/NICHD T32HD087978May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Phase I and IIa trial of atorvastatin in children with acute Kawasaki disease
    NIH/NICHD R01HD081296Sep 23, 2014 - Jun 30, 2018
    Role: Principal Investigator
    Pharmacologic Determinants for Optimized Therapy in HIV-Infected Children
    NIH/NICHD K23HD056939Sep 1, 2007 - Aug 31, 2013
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and Hyperinflammation in COVID-19. Version 1. Arthritis Rheumatol. 2020 Jul 23. Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, F Son MB, Tremoulet AH, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ. PMID: 32705809.
      View in: PubMed   Mentions:    Fields:    
    2. Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA. 2020 Jun 08. Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, Ramnarayan P, Fraisse A, Miller O, Davies P, Kucera F, Brierley J, McDougall M, Carter M, Tremoulet A, Shimizu C, Herberg J, Burns JC, Lyall H, Levin M. PMID: 32511692.
      View in: PubMed   Mentions: 8     Fields:    
    3. High-Throughput Screening of Kawasaki Disease Sera for Antiviral Antibodies. J Infect Dis. 2020 May 09. Quiat D, Kula T, Shimizu C, Kanegaye JT, Tremoulet AH, Pitkowsky Z, Son M, Newburger JW, Elledge SJ, Burns JC. PMID: 32386318.
      View in: PubMed   Mentions:    Fields:    
    4. A Four-Year-Old with History of Kawasaki Disease Presenting in Acute Shock. Prehosp Emerg Care. 2020 May 01; 1-8. Staats K, Tremoulet AH, Harvey H, Burns JC, Donofrio-Odmann JJ. PMID: 32250719.
      View in: PubMed   Mentions:    Fields:    
    5. Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents. Clin Transl Sci. 2020 Apr 23. Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, Atz A, Delmore P, Tremoulet A, Harper B, Payne E, Lin S, Erinjeri J, Cohen-Wolkowiez M, Gonzalez D. PMID: 32324313.
      View in: PubMed   Mentions:    Fields:    
    6. Management of Myocardial Infarction in Children with Giant Coronary Artery Aneurysms after Kawasaki Disease. J Pediatr. 2020 Jun; 221:230-234. Burns JC, El-Said H, Tremoulet AH, Friedman K, Gordon JB, Newburger JW. PMID: 32312552.
      View in: PubMed   Mentions:    Fields:    
    7. Hemolysis From Intravenous Immunoglobulin in Obese Patients With Kawasaki Disease. Front Pediatr. 2020; 8:146. Van Anh KY, Shah S, Tremoulet AH. PMID: 32318529.
      View in: PubMed   Mentions:
    8. Paradoxical Antibiotic Effect of Ampicillin: Use of a Population Pharmacokinetic Model to Evaluate a Clinical Correlate of the Eagle Effect in Infants With Bacteremia. Pediatr Infect Dis J. 2020 Mar 30. Ericson JE, Hornik CP, Greenberg RG, Clark RH, Tremoulet AH, Le J, Cohen-Wolkowiez M, Smith PB, Benjamin DK. PMID: 32235247.
      View in: PubMed   Mentions:    Fields:    
    9. Multicentre validation of a computer-based tool for differentiation of acute Kawasaki disease from clinically similar febrile illnesses. Arch Dis Child. 2020 Mar 05. Hao S, Ling XB, Kanegaye JT, Bainto E, Dominguez SR, Heizer H, Jone PN, Anderson MS, Jaggi P, Baker A, Son MB, Newburger JW, Ashouri N, McElhinney DB, Burns JC, Whitin JC, Cohen HJ, Tremoulet AH. PMID: 32139365.
      View in: PubMed   Mentions:    Fields:    
    10. Intravenous Immunoglobulin Infusion Reactions in Kawasaki Disease Patients Who Undergo Sedation. J Pediatr Pharmacol Ther. 2020; 25(3):251-255. Nguyen E, Hershey D, Romanowski G, Tremoulet A. PMID: 32265610.
      View in: PubMed   Mentions:
    11. Biomarkers of Inflammation and Fibrosis in Kawasaki Disease Patients Years After Initial Presentation With Low Ejection Fraction. J Am Heart Assoc. 2020 01 07; 9(1):e014569. Hoshino S, Shimizu C, Jain S, He F, Tremoulet AH, Burns JC. PMID: 31880981.
      View in: PubMed   Mentions:    Fields:    
    12. Phase I/IIa Trial of Atorvastatin in Patients with Acute Kawasaki Disease with Coronary Artery Aneurysm. J Pediatr. 2019 12; 215:107-117.e12. Tremoulet AH, Jain S, Jone PN, Best BM, Duxbury EH, Franco A, Printz B, Dominguez SR, Heizer H, Anderson MS, Glodé MP, He F, Padilla RL, Shimizu C, Bainto E, Pancheri J, Cohen HJ, Whitin JC, Burns JC. PMID: 31561960.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    13. Risk Model Development and Validation for Prediction of Coronary Artery Aneurysms in Kawasaki Disease in a North American Population. J Am Heart Assoc. 2019 06 04; 8(11):e011319. Son MBF, Gauvreau K, Tremoulet AH, Lo M, Baker AL, de Ferranti S, Dedeoglu F, Sundel RP, Friedman KG, Burns JC, Newburger JW. PMID: 31130036.
      View in: PubMed   Mentions: 1     Fields:    
    14. HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease. Hum Immunol. 2019 Sep; 80(9):731-738. Shimizu C, Kim J, Eleftherohorinou H, Wright VJ, Hoang LT, Tremoulet AH, Franco A, Hibberd ML, Takahashi A, Kubo M, Ito K, Tanaka T, Onouchi Y, Coin LJM, Levin M, Burns JC, Shike H. PMID: 31122742.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Author Correction: Clustering and climate associations of Kawasaki Disease in San Diego County suggest environmental triggers. Sci Rep. 2019 May 09; 9(1):7401. Rypdal M, Rypdal V, Burney JA, Cayan D, Bainto E, Skochko S, Tremoulet AH, Creamean J, Shimizu C, Kim J, Burns JC. PMID: 31068599.
      View in: PubMed   Mentions:    Fields:    
    16. Treatment Intensification in Patients With Kawasaki Disease and Coronary Aneurysm at Diagnosis. Pediatrics. 2019 06; 143(6). Dionne A, Burns JC, Dahdah N, Tremoulet AH, Gauvreau K, de Ferranti SD, Baker AL, Son MB, Gould P, Fournier A, Newburger JW, Friedman KG. PMID: 31048414.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Circulating Markers of Inflammation Persist in Children and Adults With Giant Aneurysms After Kawasaki Disease. Circ Genom Precis Med. 2019 04; 12(4):e002433. Lech M, Guess J, Duffner J, Oyamada J, Shimizu C, Hoshino S, Farutin V, Bulik DA, Gutierrez B, Sarvaiya H, Kapoor B, Koppes L, Saldova R, Stockmann H, Albrecht S, McManus C, Rudd PM, Kaundinya GV, Manning AM, Bosques CJ, Kahn AM, Daniels LB, Gordon JB, Tremoulet AH, Capila I, Gunay NS, Ling LE, Burns JC. PMID: 30844302.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. The Kawasaki Disease Comparative Effectiveness (KIDCARE) trial: A phase III, randomized trial of second intravenous immunoglobulin versus infliximab for resistant Kawasaki disease. Contemp Clin Trials. 2019 04; 79:98-103. Roberts SC, Jain S, Tremoulet AH, Kim KK, Burns JC, Anand V, Anderson M, Ang J, Ansusinha E, Arditi M, Ashouri N, Bartlett A, Chatterjee A, DeBiasi R, Dekker C, DeZure C, Didion L, Dominguez S, El Feghaly R, Erdem G, Halasa N, Harahsheh A, Jackson MA, Jaggi P, Jain S, Jone PN, Kaushik N, Kurio G, Lillian A, Lloyd D, Manaloor J, McNelis A, Michalik DE, Newburger J, Newcomer C, Perkins T, Portman M, Romero J, Ronis T, Rowley A, Schneider K, Schuster J, Tejtel SKS, Sharma K, Simonsen K, Szmuszkovicz J, Truong D, Wood J, Yeh S. PMID: 30840903.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    19. Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence. Nat Med. 2019 03; 25(3):433-438. Liang H, Tsui BY, Ni H, Valentim CCS, Baxter SL, Liu G, Cai W, Kermany DS, Sun X, Chen J, He L, Zhu J, Tian P, Shao H, Zheng L, Hou R, Hewett S, Li G, Liang P, Zang X, Zhang Z, Pan L, Cai H, Ling R, Li S, Cui Y, Tang S, Ye H, Huang X, He W, Liang W, Zhang Q, Jiang J, Yu W, Gao J, Ou W, Deng Y, Hou Q, Wang B, Yao C, Liang Y, Zhang S, Duan Y, Zhang R, Gibson S, Zhang CL, Li O, Zhang ED, Karin G, Nguyen N, Wu X, Wen C, Xu J, Xu W, Wang B, Wang W, Li J, Pizzato B, Bao C, Xiang D, He W, He S, Zhou Y, Haw W, Goldbaum M, Tremoulet A, Hsu CN, Carter H, Zhu L, Zhang K, Xia H. PMID: 30742121.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    20. Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease. Clin Pharmacokinet. 2018 12; 57(12):1593-1601. Vande Casteele N, Oyamada J, Shimizu C, Best BM, Capparelli EV, Tremoulet AH, Burns JC. PMID: 29623653.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Association of Initially Normal Coronary Arteries With Normal Findings on Follow-up Echocardiography in Patients With Kawasaki Disease. JAMA Pediatr. 2018 12 01; 172(12):e183310. de Ferranti SD, Gauvreau K, Friedman KG, Tang A, Baker AL, Fulton DR, Tremoulet AH, Burns JC, Newburger JW. PMID: 30285057.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Clustering and climate associations of Kawasaki Disease in San Diego County suggest environmental triggers. Sci Rep. 2018 11 12; 8(1):16140. Rypdal M, Rypdal V, Burney JA, Cayan D, Bainto E, Skochko S, Tremoulet AH, Creamean J, Shimizu C, Kim J, Burns JC. PMID: 30420674.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    23. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2019 04 30; 92(18):e2118-e2126. Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. PMID: 30413631.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. Bifid T waves on the ECG and genetic variation in calcium channel voltage-dependent beta 2 subunit gene (CACNB2) in acute Kawasaki disease. Congenit Heart Dis. 2019 Mar; 14(2):213-220. Oyamada J, Shimizu C, Kim J, Williams MR, Png E, Hibberd ML, Tremoulet AH, Perry JC, Burns JC. PMID: 30395415.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature. JAMA Pediatr. 2018 10 01; 172(10):e182293. Wright VJ, Herberg JA, Kaforou M, Shimizu C, Eleftherohorinou H, Shailes H, Barendregt AM, Menikou S, Gormley S, Berk M, Hoang LT, Tremoulet AH, Kanegaye JT, Coin LJM, Glodé MP, Hibberd M, Kuijpers TW, Hoggart CJ, Burns JC, Levin M. PMID: 30083721.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    26. Kawasaki Disease Outcomes and Response to Therapy in a Multiethnic Community: A 10-Year Experience. J Pediatr. 2018 12; 203:408-415.e3. Skochko SM, Jain S, Sun X, Sivilay N, Kanegaye JT, Pancheri J, Shimizu C, Sheets R, Tremoulet AH, Burns JC. PMID: 30268398.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease. PLoS One. 2018; 13(5):e0197858. Jaggi P, Mejias A, Xu Z, Yin H, Moore-Clingenpeel M, Smith B, Burns JC, Tremoulet AH, Jordan-Villegas A, Chaussabel D, Texter K, Pascual V, Ramilo O. PMID: 29813106.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    28. Pediatric tolerogenic DCs expressing CD4 and immunoglobulin-like transcript receptor (ILT)-4 secrete IL-10 in response to Fc and adenosine. Eur J Immunol. 2018 03; 48(3):482-491. Franco A, Kumar J, Lin G, Behnamfar N, Hsieh LE, Shimizu C, Tremoulet AH, Burns JC, Linden J. PMID: 29244203.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    29. Development of Tolerance to Chronic Intermittent Furosemide Therapy in Pediatric Patients. J Pediatr Pharmacol Ther. 2017 Nov-Dec; 22(6):394-398. Kim GJ, Capparelli E, Romanowski G, Proudfoot JA, Tremoulet AH. PMID: 29290738.
      View in: PubMed   Mentions:
    30. Adjunctive therapies in Kawasaki disease. Int J Rheum Dis. 2018 Jan; 21(1):76-79. Tremoulet AH. PMID: 29076637.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Fever without a source: evolution of a diagnosis from Kawasaki disease to acute myelogenous leukaemia. BMJ Case Rep. 2017 May 06; 2017. Lee B, Kofman CD, Tremoulet AH, Kuo DJ. PMID: 28478386.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. High Risk of Coronary Artery Aneurysms in Infants Younger than 6 Months of Age with Kawasaki Disease. J Pediatr. 2017 06; 185:112-116.e1. Salgado AP, Ashouri N, Berry EK, Sun X, Jain S, Burns JC, Tremoulet AH. PMID: 28408126.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    33. Safety of Infliximab Following Live Virus Vaccination in Kawasaki Disease Patients. Pediatr Infect Dis J. 2017 04; 36(4):435-437. Lee AM, Burns JC, Tremoulet AH. PMID: 27918378.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    34. Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility. PLoS One. 2017; 12(2):e0170977. Kim J, Shimizu C, Kingsmore SF, Veeraraghavan N, Levy E, Ribeiro Dos Santos AM, Yang H, Flatley J, Hoang LT, Hibberd ML, Tremoulet AH, Harismendy O, Ohno-Machado L, Burns JC. PMID: 28151979.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Review: Found in Translation: International Initiatives Pursuing Interleukin-1 Blockade for Treatment of Acute Kawasaki Disease. Arthritis Rheumatol. 2017 02; 69(2):268-276. Burns JC, Koné-Paut I, Kuijpers T, Shimizu C, Tremoulet A, Arditi M. PMID: 27792871.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    36. Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness. PLoS One. 2016; 11(12):e0167434. Wang Y, Li Z, Hu G, Hao S, Deng X, Huang M, Ren M, Jiang X, Kanegaye JT, Ha KS, Lee J, Li X, Jiang X, Yu Y, Tremoulet AH, Burns JC, Whitin JC, Shin AY, Sylvester KG, McElhinney DB, Cohen HJ, Ling XB. PMID: 28002448.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease. Circ Res. 2017 Jan 20; 120(2):354-365. He M, Chen Z, Martin M, Zhang J, Sangwung P, Woo B, Tremoulet AH, Shimizu C, Jain MK, Burns JC, Shyy JY. PMID: 27923814.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    38. Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated With Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities. Circ Cardiovasc Genet. 2016 Dec; 9(6):559-568. Shimizu C, Eleftherohorinou H, Wright VJ, Kim J, Alphonse MP, Perry JC, Cimaz R, Burgner D, Dahdah N, Hoang LT, Khor CC, Salgado A, Tremoulet AH, Davila S, Kuijpers TW, Hibberd ML, Johnson TA, Takahashi A, Tsunoda T, Kubo M, Tanaka T, Onouchi Y, Yeung RS, Coin LJ, Levin M, Burns JC. PMID: 27879314.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    39. Coronary Artery Aneurysms in Kawasaki Disease: Risk Factors for Progressive Disease and Adverse Cardiac Events in the US Population. J Am Heart Assoc. 2016 09 15; 5(9). Friedman KG, Gauvreau K, Hamaoka-Okamoto A, Tang A, Berry E, Tremoulet AH, Mahavadi VS, Baker A, deFerranti SD, Fulton DR, Burns JC, Newburger JW. PMID: 27633390.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    40. Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. BMC Pediatr. 2016 09 05; 16(1):151. Connelly MA, Shimizu C, Winegar DA, Shalaurova I, Pourfarzib R, Otvos JD, Kanegaye JT, Tremoulet AH, Burns JC. PMID: 27596163.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    41. Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates. J Pediatr. 2016 Nov; 178:125-129.e1. Hornik CP, Benjamin DK, Smith PB, Pencina MJ, Tremoulet AH, Capparelli EV, Ericson JE, Clark RH, Cohen-Wolkowiez M. PMID: 27522443.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children. JAMA. 2016 Aug 23-30; 316(8):835-45. Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M. PMID: 27552617.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    43. A Classification Tool for Differentiation of Kawasaki Disease from Other Febrile Illnesses. J Pediatr. 2016 09; 176:114-120.e8. Hao S, Jin B, Tan Z, Li Z, Ji J, Hu G, Wang Y, Deng X, Kanegaye JT, Tremoulet AH, Burns JC, Cohen HJ, Ling XB. PMID: 27344221.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Building a Natural Language Processing Tool to Identify Patients With High Clinical Suspicion for Kawasaki Disease from Emergency Department Notes. Acad Emerg Med. 2016 05; 23(5):628-36. Doan S, Maehara CK, Chaparro JD, Lu S, Liu R, Graham A, Berry E, Hsu CN, Kanegaye JT, Lloyd DD, Ohno-Machado L, Burns JC, Tremoulet AH. PMID: 26826020.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    45. Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (the ANAKID trial). Contemp Clin Trials. 2016 05; 48:70-5. Tremoulet AH, Jain S, Kim S, Newburger J, Arditi M, Franco A, Best B, Burns JC. PMID: 27080929.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    46. Psoriasiform eruptions during Kawasaki disease (KD): A distinct phenotype. J Am Acad Dermatol. 2016 Jul; 75(1):69-76.e2. Haddock ES, Calame A, Shimizu C, Tremoulet AH, Burns JC, Tom WL. PMID: 26946987.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Urinary Colorimetric Sensor Array and Algorithm to Distinguish Kawasaki Disease from Other Febrile Illnesses. PLoS One. 2016; 11(2):e0146733. Li Z, Tan Z, Hao S, Jin B, Deng X, Hu G, Liu X, Zhang J, Jin H, Huang M, Kanegaye JT, Tremoulet AH, Burns JC, Wu J, Cohen HJ, Ling XB. PMID: 26859297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Axillary, Oral and Rectal Routes of Temperature Measurement During Treatment of Acute Kawasaki Disease. Pediatr Infect Dis J. 2016 Jan; 35(1):50-3. Kanegaye JT, Jones JM, Burns JC, Jain S, Sun X, Jimenez-Fernandez S, Berry E, Pancheri JM, Jaggi P, Ramilo O, Tremoulet AH. PMID: 26398742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Pulmonary Artery Dilation and Right Ventricular Function in Acute Kawasaki Disease. Pediatr Cardiol. 2016 Mar; 37(3):482-90. Numano F, Shimizu C, Tremoulet AH, Dyar D, Burns JC, Printz BF. PMID: 26681305.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. Patterns of Fever in Children After Primary Treatment for Kawasaki Disease. Pediatr Infect Dis J. 2015 Dec; 34(12):1315-8. Jaggi P, Wang W, Dvorchik I, Printz B, Berry E, Kovalchin JP, Texter K, Ramilo O, Burns JC, Tremoulet AH. PMID: 26353031.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Novel data-mining approach identifies biomarkers for diagnosis of Kawasaki disease. Pediatr Res. 2015 Nov; 78(5):547-53. Tremoulet AH, Dutkowski J, Sato Y, Kanegaye JT, Ling XB, Burns JC. PMID: 26237629.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    52. Galectin-3 is a marker of myocardial and vascular fibrosis in Kawasaki disease patients with giant aneurysms. Int J Cardiol. 2015 Dec 15; 201:429-37. Numano F, Shimizu C, Jimenez-Fernandez S, Vejar M, Oharaseki T, Takahashi K, Salgado A, Tremoulet AH, Gordon JB, Burns JC, Daniels LB. PMID: 26313861.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    53. Evaluating a novel treatment for coronary artery inflammation in acute Kawasaki disease: A Phase I/IIa trial of atorvastatin. Expert Opin Orphan Drugs. 2015; 3(9):967-970. Tremoulet AH, Jain S, Burns JC. PMID: 27525197.
      View in: PubMed   Mentions:
    54. The role of statins in inflammatory vasculitides. Autoimmunity. 2015 May; 48(3):177-80. Tremoulet AH. PMID: 25822883.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    55. Fine specificities of natural regulatory T cells after IVIG therapy in patients with Kawasaki disease. Autoimmunity. 2015 May; 48(3):181-8. Burns JC, Touma R, Song Y, Padilla RL, Tremoulet AH, Sidney J, Sette A, Franco A. PMID: 25822882.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    56. Global gene expression profiling identifies new therapeutic targets in acute Kawasaki disease. Genome Med. 2014; 6(11):541. Hoang LT, Shimizu C, Ling L, Naim AN, Khor CC, Tremoulet AH, Wright V, Levin M, Hibberd ML, Burns JC. PMID: 25614765.
      View in: PubMed   Mentions: 26     Fields:    
    57. Kawasaki Disease in Latin American Children: Past, Current, and Future Challenges. J Pediatric Infect Dis Soc. 2014 Dec; 3(4):280-1. Ulloa-Gutierrez R, Salgado AP, Tremoulet AH. PMID: 26625447.
      View in: PubMed   Mentions: 2     Fields:    
    58. Optimizing pediatric esmolol dosing using computerized practitioner order entry. J Pediatr Pharmacol Ther. 2014 Oct-Dec; 19(4):302-9. Chao T, Perry JC, Romanowski GL, Tremoulet AH, Capparelli EV. PMID: 25762876.
      View in: PubMed   Mentions:
    59. Lipoprotein particle concentrations in children and adults following Kawasaki disease. J Pediatr. 2014 Oct; 165(4):727-31. Lin J, Jain S, Sun X, Liu V, Sato YZ, Jimenez-Fernandez S, Newfield RS, Pourfarzib R, Tremoulet AH, Gordon JB, Daniels LB, Burns JC. PMID: 25039043.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    60. Origin and importance of the Latin American Kawasaki Disease Network (REKAMLATINA). Rev Chilena Infectol. 2014 Jun; 31(3):330-2. González-Mata A, Ulloa-Gutiérrez R, Brea J, Soza G, Tremoulet AH. PMID: 25146208.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    61. Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Antimicrob Agents Chemother. 2014 Jun; 58(6):3013-20. Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK, Capparelli EV, Cohen-Wolkowiez M. PMID: 24614374.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    62. Infliximab for intensification of primary therapy for Kawasaki disease: a phase 3 randomised, double-blind, placebo-controlled trial. Lancet. 2014 May 17; 383(9930):1731-8. Tremoulet AH, Jain S, Jaggi P, Jimenez-Fernandez S, Pancheri JM, Sun X, Kanegaye JT, Kovalchin JP, Printz BF, Ramilo O, Burns JC. PMID: 24572997.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCTClinical Trials
    63. Specificity of regulatory T cells that modulate vascular inflammation. Autoimmunity. 2014 Mar; 47(2):95-104. Franco A, Touma R, Song Y, Shimizu C, Tremoulet AH, Kanegaye JT, Burns JC. PMID: 24490882.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    64. Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G. PLoS One. 2013; 8(12):e81448. Ogata S, Shimizu C, Franco A, Touma R, Kanegaye JT, Choudhury BP, Naidu NN, Kanda Y, Hoang LT, Hibberd ML, Tremoulet AH, Varki A, Burns JC. PMID: 24324693.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    65. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. Clin Exp Immunol. 2013 Dec; 174(3):337-44. Burns JC, Song Y, Bujold M, Shimizu C, Kanegaye JT, Tremoulet AH, Franco A. PMID: 23901839.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    66. Hoarseness as a presenting sign in children with Kawasaki disease. Pediatr Infect Dis J. 2013 Dec; 32(12):1392-4. Leuin SC, Shanbhag S, Lago D, Sato Y, Sun X, Jain S, Burns JC, Tremoulet AH. PMID: 23811742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Comment on atorvastatin safety in kawasaki disease patients with coronary artery aneurysms. Pediatr Cardiol. 2014 Jan; 35(1):93. Tremoulet AH. PMID: 24072043.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    68. Seasonality of Kawasaki disease: a global perspective. PLoS One. 2013; 8(9):e74529. Burns JC, Herzog L, Fabri O, Tremoulet AH, Rodó X, Uehara R, Burgner D, Bainto E, Pierce D, Tyree M, Cayan D. PMID: 24058585.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    69. [Origin and importance of the Latin American Kawasaki Disease Network (REKAMLATINA)]. Rev Chilena Infectol. 2013 Aug; 30(4):402-4. González-Mata A, Ulloa-Gutierrez R, Brea del Castillo J, Soza G, Tremoulet AH. PMID: 24248109.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    70. Coronary artery outcomes among children with Kawasaki disease in the United States and Japan. Int J Cardiol. 2013 Oct 09; 168(4):3825-8. Ogata S, Tremoulet AH, Sato Y, Ueda K, Shimizu C, Sun X, Jain S, Silverstein L, Baker AL, Tanaka N, Ogihara Y, Ikehara S, Takatsuki S, Sakamoto N, Kobayashi T, Fuse S, Matsubara T, Ishii M, Saji T, Newburger JW, Burns JC. PMID: 23849968.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    71. A simple method for assessment of human anti-Neu5Gc antibodies applied to Kawasaki disease. PLoS One. 2013; 8(3):e58443. Padler-Karavani V, Tremoulet AH, Yu H, Chen X, Burns JC, Varki A. PMID: 23520510.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    72. Differential expression of miR-145 in children with Kawasaki disease. PLoS One. 2013; 8(3):e58159. Shimizu C, Kim J, Stepanowsky P, Trinh C, Lau HD, Akers JC, Chen C, Kanegaye JT, Tremoulet A, Ohno-Machado L, Burns JC. PMID: 23483985.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    73. Lymph-node-first presentation of Kawasaki disease compared with bacterial cervical adenitis and typical Kawasaki disease. J Pediatr. 2013 Jun; 162(6):1259-63, 1263.e1-2. Kanegaye JT, Van Cott E, Tremoulet AH, Salgado A, Shimizu C, Kruk P, Hauschildt J, Sun X, Jain S, Burns JC. PMID: 23305955.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    74. Infliximab treatment of pancreatitis complicating acute kawasaki disease. Pediatr Infect Dis J. 2012 Oct; 31(10):1087-9. Jimenez-Fernandez SG, Tremoulet AH. PMID: 22653489.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    75. Coronary artery dilation in acute Kawasaki disease and acute illnesses associated with Fever. Pediatr Infect Dis J. 2012 Sep; 31(9):924-6. Bratincsak A, Reddy VD, Purohit PJ, Tremoulet AH, Molkara DP, Frazer JR, Dyar D, Bush RA, Sim JY, Sang N, Burns JC, Melish MA. PMID: 22673140.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    76. Point-of-care differentiation of Kawasaki disease from other febrile illnesses. J Pediatr. 2013 Jan; 162(1):183-188.e3. Ling XB, Kanegaye JT, Ji J, Peng S, Sato Y, Tremoulet A, Burns JC, Cohen HJ. PMID: 22819274.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    77. Prolonged urticaria and fever in a toddler. Allergy Asthma Proc. 2012 May-Jun; 33(3):297-301. Broderick L, Tremoulet AH, Burns JC, Hoffman HM. PMID: 22584197.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    78. Calcineurin inhibitor treatment of intravenous immunoglobulin-resistant Kawasaki disease. J Pediatr. 2012 Sep; 161(3):506-512.e1. Tremoulet AH, Pancoast P, Franco A, Bujold M, Shimizu C, Onouchi Y, Tamamoto A, Erdem G, Dodd D, Burns JC. PMID: 22484354.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    79. Developmental pharmacokinetic changes of Lamivudine in infants and children. J Clin Pharmacol. 2012 Dec; 52(12):1824-32. Tremoulet AH, Nikanjam M, Cressey TR, Chokephaibulkit K, McKinney R, Mirochnick M, Capparelli EV. PMID: 22180560.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    80. Evolution of laboratory values in patients with Kawasaki disease. Pediatr Infect Dis J. 2011 Dec; 30(12):1022-6. Tremoulet AH, Jain S, Chandrasekar D, Sun X, Sato Y, Burns JC. PMID: 21817952.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    81. Increased incidence and severity of Kawasaki disease among Filipino-Americans in San Diego county. Pediatr Infect Dis J. 2011 Oct; 30(10):909-11. Tremoulet AH, Devera G, Best BM, Jimenez-Fernandez S, Sun X, Jain S, Burns JC. PMID: 21552184.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    82. Cardiovascular biomarkers in acute Kawasaki disease. Int J Cardiol. 2013 Mar 20; 164(1):58-63. Sato YZ, Molkara DP, Daniels LB, Tremoulet AH, Shimizu C, Kanegaye JT, Best BM, Snider JV, Frazer JR, Maisel A, Burns JC. PMID: 21777987.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    83. Recurrent fever syndromes in patients after recovery from Kawasaki syndrome. Pediatrics. 2011 Feb; 127(2):e489-93. Broderick L, Tremoulet AH, Burns JC, Bastian JF, Hoffman HM. PMID: 21220401.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. Cross-reactive neutralizing antibody against pandemic 2009 H1N1 influenza a virus in intravenous immunoglobulin preparations. Pediatr Infect Dis J. 2011 Jan; 30(1):67-9. Hong DK, Tremoulet AH, Burns JC, Lewis DB. PMID: 20724956.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    85. Infliximab for intravenous immunoglobulin resistance in Kawasaki disease: a retrospective study. J Pediatr. 2011 Apr; 158(4):644-649.e1. Son MB, Gauvreau K, Burns JC, Corinaldesi E, Tremoulet AH, Watson VE, Baker A, Fulton DR, Sundel RP, Newburger JW. PMID: 21129756.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    86. Transforming growth factor-beta signaling pathway in patients with Kawasaki disease. Circ Cardiovasc Genet. 2011 Feb; 4(1):16-25. Shimizu C, Jain S, Davila S, Hibberd ML, Lin KO, Molkara D, Frazer JR, Sun S, Baker AL, Newburger JW, Rowley AH, Shulman ST, Davila S, Burgner D, Breunis WB, Kuijpers TW, Wright VJ, Levin M, Eleftherohorinou H, Coin L, Popper SJ, Relman DA, Fury W, Lin C, Mellis S, Tremoulet AH, Burns JC. PMID: 21127203.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    87. Transcript abundance patterns in Kawasaki disease patients with intravenous immunoglobulin resistance. Hum Immunol. 2010 Sep; 71(9):865-73. Fury W, Tremoulet AH, Watson VE, Best BM, Shimizu C, Hamilton J, Kanegaye JT, Wei Y, Kao C, Mellis S, Lin C, Burns JC. PMID: 20600450.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    88. Memory T-cells and characterization of peripheral T-cell clones in acute Kawasaki disease. Autoimmunity. 2010 Jun; 43(4):317-24. Franco A, Shimizu C, Tremoulet AH, Burns JC. PMID: 20166878.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    89. Recognition of a Kawasaki disease shock syndrome. Pediatrics. 2009 May; 123(5):e783-9. Kanegaye JT, Wilder MS, Molkara D, Frazer JR, Pancheri J, Tremoulet AH, Watson VE, Best BM, Burns JC. PMID: 19403470.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    90. Resistance to intravenous immunoglobulin in children with Kawasaki disease. J Pediatr. 2008 Jul; 153(1):117-21. Tremoulet AH, Best BM, Song S, Wang S, Corinaldesi E, Eichenfield JR, Martin DD, Newburger JW, Burns JC. PMID: 18571548.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    91. Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants. Antimicrob Agents Chemother. 2007 Dec; 51(12):4297-302. Tremoulet AH, Capparelli EV, Patel P, Acosta EP, Luzuriaga K, Bryson Y, Wara D, Zorrilla C, Holland D, Mirochnick M. PMID: 17893155.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    92. Novel therapies for rheumatoid arthritis. Expert Opin Investig Drugs. 2006 Nov; 15(11):1427-41. Tremoulet AH, Albani S. PMID: 17040201.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    93. Immunomics in clinical development: bridging the gap. Expert Rev Clin Immunol. 2005 May; 1(1):3-6. Tremoulet AH, Albani S. PMID: 20477648.
      View in: PubMed   Mentions:    Fields:    
    94. Albendazole therapy for Microsporidium diarrhea in immunocompetent Costa Rican children. Pediatr Infect Dis J. 2004 Oct; 23(10):915-8. Tremoulet AH, Avila-Aguero ML, París MM, Canas-Coto A, Ulloa-Gutierrez R, Faingezicht I. PMID: 15602190.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCTClinical Trials
    95. [Tumor of the thymic loge in a 6-year-old child]. Pediatrie. 1961; 16:92-3. ROUSSEL A, BARBE A, LONGEFAIT M, TREMOULET A. PMID: 13744009.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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