Brookie Best

Title(s)Dean, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0001-8569-2293 Additional info
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    Dr. Brookie Best is the Dean at the University of California (UC), San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) and is a Professor of Clinical Pharmacy and Pediatrics at SSPPS and in the UC San Diego Department of Pediatrics, School of Medicine (SOM) - Rady Children's Hospital San Diego. She completed a Bachelor of Science degree at UC San Diego in Chemistry with an Emphasis in Chemical Education in 1994. She received her Pharm.D. degree in 1999 from UC San Francisco, and did her residency in Pharmacy Practice at the UC San Diego Medical Center in 2000. Dr. Best was an NICHD/NIH Fellowship recipient in Pediatric Clinical Pharmacology Research from 2001 to 2004, and completed a Masters of Advanced Studies (M.A.S.) in Clinical Research at UC San Diego in 2007. Dr. Best specializes in pharmacokinetics - the processes by which a drug is absorbed, distributed, metabolized and eliminated by the body - and maternal/fetal and pediatric clinical pharmacology research. Her research efforts have focused on studying anti-HIV drugs in pregnant women, children and non-pregnant adults. She also studies drugs used to treat Kawasaki disease, the leading cause of acquired heart disease in children.

    Collapse Research 
    Collapse Research Activities and Funding
    Developmental and Translational Pharmacology of Pediatric Antimicrobial Therapy
    NIH U54HD071600Sep 26, 2011 - Jun 30, 2016
    Role: Co-Investigator
    Predoctoral Research Training in Maternal and Pediatric Pharmacology
    NIH T35HD064385Apr 1, 2010 - Apr 30, 2022
    Role: Principal Investigator
    PEDIATRIC CLINICAL RESEARCH PHARMACOLOGY FELLOWSHIP
    NIH F32HD008722Apr 1, 2001
    Role: Principal Investigator

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    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pharmacokinetics and Safety of Remdesivir in Pregnant and Non-Pregnant Women with COVID-19: Results from IMPAACT 2032. J Infect Dis. 2024 Jun 05. Brooks KM, Baltrusaitis K, Clarke DF, Nachman S, Jao J, Purswani MU, Agwu A, Beneri C, Deville JG, Powis KM, Stek AM, Eke AC, Shapiro DE, Capparelli E, Greene E, George K, Yin DE, Jean-Philippe P, Chakhtoura N, Bone F, Bacon K, Johnston B, Reding C, Kersey K, Humeniuk R, Best BM, Mirochnick M, Momper JD. PMID: 38839047.
      View in: PubMed   Mentions:    Fields:    
    2. Safety and pharmacokinetics of oral and long-acting injectable cabotegravir or long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study. Lancet HIV. 2024 Apr; 11(4):e211-e221. Gaur AH, Capparelli EV, Calabrese K, Baltrusaitis K, Marzinke MA, McCoig C, Van Solingen-Ristea RM, Mathiba SR, Adeyeye A, Moye JH, Heckman B, Lowenthal ED, Ward S, Milligan R, Samson P, Best BM, Harrington CM, Ford SL, Huang J, Crauwels H, Vandermeulen K, Agwu AL, Smith-Anderson C, Camacho-Gonzalez A, Ounchanum P, Kneebone JL, Townley E, Bolton Moore C, IMPAACT 2017 Collaborators, IMPAACT 2017 Team. PMID: 38538160; PMCID: PMC11213970.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. Concentrations of remdesivir and GS-441524 in human milk from lactating individuals diagnosed with COVID-19. Pediatr Res. 2024 Feb 12. Bertrand K, Sepulveda Y, Spiegel BJ, Best BM, Suhandynata R, Rossi S, Chambers CD, Momper JD. PMID: 38347172.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Efficacy, Safety, and Tolerability of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination Tablets in Adolescents Living With HIV: Results Through Week 96 from IMPAACT 2014. J Pediatric Infect Dis Soc. 2023 Dec 16; 12(12):602-609. Rungmaitree S, Aurpibul L, Best BM, Li X, Warshaw MG, Wan H, Tobin NH, Jumes P, Leavitt R, McCarthy K, Scheckter R, Ounchanum P, Violari A, Teppler H, Campbell H, Krotje C, Townley E, Moye J, Melvin AJ, IMPAACT 2014 study team . PMID: 37815035.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2023 12 01; 94(4):332-336. Momper JD, Nikanjam M, Best BM, Mirochnick M, Capparelli EV, Cressey TR. PMID: 37884053; PMCID: PMC10686188.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Pharmacokinetics and safety of first-line tuberculosis drugs rifampin, isoniazid, ethambutol, and pyrazinamide during pregnancy and postpartum: results from IMPAACT P1026s. Antimicrob Agents Chemother. 2023 11 15; 67(11):e0073723. Van Schalkwyk M, Bekker A, Decloedt E, Wang J, Theron GB, Cotton MF, Eke AC, Cressey TR, Shapiro DE, Bacon K, Knowles K, George K, Browning R, Chakhtoura N, Rungruengthanakit K, Wiesner L, Capparelli EV, Stek AM, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 37882552; PMCID: PMC10648924.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Cannabidiol Exposure Through Maternal Marijuana Use: Predictions in Breastfed Infants. Clin Pharmacokinet. 2023 11; 62(11):1611-1619. Yeung CHT, Bertrand KA, Best BM, Capparelli E, Chambers CD, Hajducek DM, Hamadeh A, Ito S, Momper JD, Edginton AN. PMID: 37735347; PMCID: PMC10659070.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Translating Clinical Pharmacology Data in Pregnancy to Evidence-Based Guideline Recommendations: Perspectives From the HIV Field. J Clin Pharmacol. 2023 06; 63 Suppl 1:S188-S196. Brooks KM, Scott RK, Best BM, Capparelli E, Momper JD. PMID: 37317495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. An Open Label, Randomized, Multicenter Study of Elafibranor in Children With Nonalcoholic Steatohepatitis. J Pediatr Gastroenterol Nutr. 2023 08 01; 77(2):160-165. Goyal NP, Mencin A, Newton KP, Durelle J, Carrier C, Ugalde-Nicalo P, Noel B, Mouton J, Vargas D, Magrez D, Tadde B, Birman P, Best BM, Addy C, Schwimmer JB. PMID: 37084342; PMCID: PMC10523882.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    10. Addressing maternal medication use during breastfeeding using clinical resources and a novel physiologically based pharmacokinetic model-derived metric: A qualitative study. Front Pediatr. 2023; 11:1147566. Yeung CHT, Houle SKD, Anderson PO, Best BM, Dubinsky S, Edginton AN. PMID: 37077336; PMCID: PMC10106747.
      View in: PubMed   Mentions:
    11. Modified team-based learning to promote collaboration in an online prematriculation course. Med Educ. 2023 05; 57(5):470-471. Schneid SD, Best BM, Evans SJ, Brandl K. PMID: 36866840.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Pharmacokinetics, Tolerability, and Safety of Doravirine and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination Tablets in Adolescents Living With HIV: Week 24 Results From IMPAACT 2014. J Acquir Immune Defic Syndr. 2023 02 01; 92(2):153-161. Melvin AJ, Yee KL, Gray KP, Yedla M, Wan H, Tobin NH, Teppler H, Campbell H, McCarthy K, Scheckter R, Aurpibul L, Ounchanum P, Rungmaitree S, Cassim H, McFarland E, Flynn P, Cooper E, Krotje C, Townley E, Moye J, Best BM, IMPAACT 2014 study team. PMID: 36215957; PMCID: PMC9839475.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Physiologically-based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID-19. CPT Pharmacometrics Syst Pharmacol. 2023 02; 12(2):148-153. Liu XI, Dallmann A, Brooks K, Best BM, Clarke DF, Mirochnick M, van den Anker JN, Capparelli EV, Momper JD. PMID: 36479969; PMCID: PMC9877749.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. The Concentration of Etanercept in Human Milk and Infant Outcomes. J Rheumatol. 2023 05; 50(5):712-714. Bertrand K, Rossi S, Wells A, Best B, Chambers CD. PMID: 36379569; PMCID: PMC10159878.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota. Pharmacotherapy. 2023 05; 43(5):442-451. Thomas SP, Denizer E, Zuffa S, Best BM, Bode L, Chambers CD, Dorrestein PC, Liu GY, Momper JD, Nizet V, Tsunoda SM, Tremoulet AH. PMID: 36181712; PMCID: PMC10763576.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Learning Outcomes in a Live Virtual versus In-Person Curriculum for Medical and Pharmacy Students. ATS Sch. 2022 Oct; 3(3):399-412. Nilaad SD, Lin E, Bailey J, Truong C, Gaboyan S, Mittal A, Best BM, Guluma K, Iglewicz A, Lander L, Evans S, Goldberg C, Crotty Alexander LE. PMID: 36312802; PMCID: PMC9585697.
      View in: PubMed   Mentions: 4  
    17. Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life. Pediatr Infect Dis J. 2022 11 01; 41(11):885-890. Liyanage M, Nikanjam M, McFadyen L, Vourvahis M, Rogg L, Moye J, Chadwick EG, Jean-Philippe P, Mirochnick M, Whitson K, Bradford S, Capparelli EV, Best BM. PMID: 35980827; PMCID: PMC9560968.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Pharmacokinetics of Tenofovir Alafenamide With Boosted Protease Inhibitors in Pregnant and Postpartum Women Living With HIV: Results From IMPAACT P1026s. J Acquir Immune Defic Syndr. 2022 07 01; 90(3):343-350. Brooks KM, Pinilla M, Stek AM, Shapiro DE, Barr E, Febo IL, Paul ME, Deville JG, George K, Knowles K, Rungruengthanakit K, Browning R, Chakhtoura N, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 35195573; PMCID: PMC9203910.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Clinical and population-based study design considerations to accelerate the investigation of new antiretrovirals during pregnancy. J Int AIDS Soc. 2022 07; 25 Suppl 2:e25917. Brummel SS, Stringer J, Mills E, Tierney C, Caniglia EC, Colbers A, Chi BH, Best BM, Gaaloul ME, Hillier S, Jourdain G, Khoo SH, Mofenson LM, Myer L, Nachman S, Stranix-Chibanda L, Clayden P, Sachikonye M, Lockman S. PMID: 35851758; PMCID: PMC9294861.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Pharmacokinetics of Atazanavir Boosted With Cobicistat in Pregnant and Postpartum Women With HIV. J Acquir Immune Defic Syndr. 2022 03 01; 89(3):303-309. Momper JD, Wang J, Stek A, Shapiro DE, Powis KM, Paul ME, Badell ML, Browning R, Chakhtoura N, Denson K, Rungruengthanakit K, George K, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34732682; PMCID: PMC8837686.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    21. Optimizing Dolutegravir Initiation in Neonates Using Population Pharmacokinetic Modeling and Simulation. J Acquir Immune Defic Syndr. 2022 01 01; 89(1):108-114. Piscitelli J, Nikanjam M, Best BM, Acosta E, Mirochnick M, Clarke DF, Capparelli EV, Momper JD. PMID: 34629412; PMCID: PMC8665018.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Anakinra Treatment in Patients with Acute Kawasaki Disease with Coronary Artery Aneurysms: A Phase I/IIa Trial. J Pediatr. 2022 04; 243:173-180.e8. Yang J, Jain S, Capparelli EV, Best BM, Son MB, Baker A, Newburger JW, Franco A, Printz BF, He F, Shimizu C, Hoshino S, Bainto E, Moreno E, Pancheri J, Burns JC, Tremoulet AH. PMID: 34953816.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    23. Brief Report: Pharmacokinetics of Bictegravir and Tenofovir in Combination With Darunavir/Cobicistat in Treatment-Experienced Persons With HIV. J Acquir Immune Defic Syndr. 2021 12 01; 88(4):389-392. Salama E, Hill L, Patel N, Best BM, Momper JD. PMID: 34285156.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development. Front Pediatr. 2021; 9:721059. Zhao S, Gockenbach M, Grimstein M, Sachs HC, Mirochnick M, Struble K, Belew Y, Wang J, Capparelli EV, Best BM, Johnson T, Momper JD, Maharaj AR. PMID: 34722417; PMCID: PMC8550258.
      View in: PubMed   Mentions: 3  
    25. Interactions between etonogestrel-releasing contraceptive implant and 3 antiretroviral regimens. Contraception. 2022 01; 105:67-74. Kreitchmann R, Stek A, Best BM, Capparelli E, Wang J, Shapiro D, Chakhtoura N, Mirochnick M, Eke AC, IMPAACT P1026s protocol team. PMID: 34407424; PMCID: PMC8678338.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Paresthesia Predicts Increased Risk of Distal Neuropathic Pain in Older People with HIV-Associated Sensory Polyneuropathy. Pain Med. 2021 08 06; 22(8):1850-1856. Diaz MM, Keltner JR, Simmons AN, Franklin D, Moore RC, Clifford D, Collier AC, Gelman BB, Marra PDC, McCutchan JA, Morgello S, Sacktor N, Best B, Notestine CF, Weibel SG, Grant I, Marcotte TD, Vaida F, Letendre S, Heaton R, Ellis RJ. PMID: 33565583; PMCID: PMC8502467.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021 Oct; 46(5):1459-1464. Mulligan N, Salama E, Momper JD, Capparelli EV, Stek A, Chakhtoura N, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34254323; PMCID: PMC8448937.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Pharmacokinetics of darunavir and cobicistat in pregnant and postpartum women with HIV. AIDS. 2021 07 01; 35(8):1191-1199. Momper JD, Wang J, Stek A, Shapiro DE, Scott GB, Paul ME, Febo IL, Burchett S, Smith E, Chakhtoura N, Denson K, Rungruengthanakit K, George K, Yang DZ, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 34076612; PMCID: PMC8173003.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    29. Pharmacokinetics of tenofovir alafenamide with and without cobicistat in pregnant and postpartum women living with HIV. AIDS. 2021 03 01; 35(3):407-417. Brooks KM, Momper JD, Pinilla M, Stek AM, Barr E, Weinberg A, Deville JG, Febo IL, Cielo M, George K, Denson K, Rungruengthanakit K, Shapiro DE, Smith E, Chakhtoura N, Rooney JF, Haubrich R, Espina R, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 33252495; PMCID: PMC8238253.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    30. Pharmacokinetics and safety of maraviroc in neonates. AIDS. 2021 03 01; 35(3):419-427. Rosebush JC, Best BM, Chadwick EG, Butler K, Moye J, Smith E, Bradford S, Reding CA, Mathiba SR, Hanley S, Aziz M, Homans J, Acosta EP, Murtaugh W, Vourvahis M, Mcfadyen L, Hayward K, Mirochnick M, Samson P, for the IMPAACT 2007 Study Team . PMID: 33252481; PMCID: PMC7856036.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. Population Pharmacokinetics of Tenofovir in Pregnant and Postpartum Women Using Tenofovir Disoproxil Fumarate. Antimicrob Agents Chemother. 2021 02 17; 65(3). Eke AC, Shoji K, Best BM, Momper JD, Stek AM, Cressey TR, Mirochnick M, Capparelli EV. PMID: 33318014; PMCID: PMC8092509.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    32. Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir. Clin Pharmacokinet. 2021 06; 60(6):795-809. Liu XI, Momper JD, Rakhmanina NY, Green DJ, Burckart GJ, Cressey TR, Mirochnick M, Best BM, van den Anker JN, Dallmann A. PMID: 33527213; PMCID: PMC9334904.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling. Clin Pharmacokinet. 2020 11; 59(11):1433-1450. Liu XI, Momper JD, Rakhmanina NY, Green DJ, Burckart GJ, Cressey TR, Mirochnick M, Best BM, van den Anker JN, Dallmann A. PMID: 32451908; PMCID: PMC7666002.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    34. Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement. Clin Pharmacol Ther. 2021 07; 110(1):36-48. Eke AC, Olagunju A, Momper J, Penazzato M, Abrams EJ, Best BM, Capparelli EV, Bekker A, Belew Y, Kiser JJ, Struble K, Taylor G, Waitt C, Mirochnick M, Cressey TR, Colbers A, participants of the WHO-IMPAACT workshop on “Approaches to Optimize and Accelerate Pharmacokinetic S. PMID: 32930408; PMCID: PMC8167886.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    35. Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV. Clin Pharmacokinet. 2020 10; 59(10):1185-1194. Eke AC, Olagunju A, Best BM, Mirochnick M, Momper JD, Abrams E, Penazzato M, Cressey TR, Colbers A. PMID: 32757103; PMCID: PMC7550310.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    36. Effectiveness of Providing Video Podcasts to Pharmacy Students in a Self-Study Pharmaceutical Calculations Module. Am J Pharm Educ. 2020 12; 84(12):ajpe7977. Mnatzaganian CL, Singh RF, Best BM, Morello CM. PMID: 34283785; PMCID: PMC7779875.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    37. Pharmacokinetic Enhancement of HIV Antiretroviral Therapy During Pregnancy. J Clin Pharmacol. 2020 12; 60(12):1537-1550. Salama E, Eke AC, Best BM, Mirochnick M, Momper JD. PMID: 32798276; PMCID: PMC8227837.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial. Lancet HIV. 2020 05; 7(5):e322-e331. João EC, Morrison RL, Shapiro DE, Chakhtoura N, Gouvèa MIS, de Lourdes B Teixeira M, Fuller TL, Mmbaga BT, Ngocho JS, Njau BN, Violari A, Mathiba R, Essack Z, Pilotto JHS, Moreira LF, Rolon MJ, Cahn P, Prommas S, Cressey TR, Chokephaibulkit K, Werarak P, Laimon L, Hennessy R, Frenkel LM, Anthony P, Best BM, Siberry GK, Mirochnick M. PMID: 32386720; PMCID: PMC7323582.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    39. Darunavir Pharmacokinetics With an Increased Dose During Pregnancy. J Acquir Immune Defic Syndr. 2020 04 01; 83(4):373-380. Eke AC, Stek AM, Wang J, Kreitchmann R, Shapiro DE, Smith E, Chakhtoura N, Capparelli EV, Mirochnick M, Best BM, IMPAACT P1026s Protocol Team. PMID: 31923087; PMCID: PMC7258985.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    40. Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy. Antimicrob Agents Chemother. 2020 03 24; 64(4). Eke AC, Wang J, Amin K, Shapiro DE, Stek A, Smith E, Chakhtoura N, Basar M, George K, Knapp KM, João EC, Rungruengthanakit K, Capparelli E, Burchett S, Mirochnick M, Best BM, P1026s Protocol Team. PMID: 32015036; PMCID: PMC7179299.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    41. Phase I/IIa Trial of Atorvastatin in Patients with Acute Kawasaki Disease with Coronary Artery Aneurysm. J Pediatr. 2019 12; 215:107-117.e12. Tremoulet AH, Jain S, Jone PN, Best BM, Duxbury EH, Franco A, Printz B, Dominguez SR, Heizer H, Anderson MS, Glodé MP, He F, Padilla RL, Shimizu C, Bainto E, Pancheri J, Cohen HJ, Whitin JC, Burns JC. PMID: 31561960; PMCID: PMC6878161.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    42. Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir. J Clin Pharmacol. 2020 02; 60(2):240-255. Liu XI, Momper JD, Rakhmanina N, van den Anker JN, Green DJ, Burckart GJ, Best BM, Mirochnick M, Capparelli EV, Dallmann A. PMID: 31489678; PMCID: PMC7316130.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    43. Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling. J Antimicrob Chemother. 2019 05 01; 74(5):1348-1356. Schalkwijk S, Ter Heine R, Colbers A, Capparelli E, Best BM, Cressey TR, Greupink R, Russel FGM, Moltó J, Mirochnick M, Karlsson MO, Burger DM. PMID: 30715324; PMCID: PMC6477987.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. Sertraline Pharmacokinetics in HIV-Infected and Uninfected Children, Adolescents, and Young Adults. Front Pediatr. 2019; 7:16. Hanan NJ, Paul ME, Huo Y, Kapetanovic S, Smith E, Siberry G, Brouwers P, Graham B, Johnston B, Capparelli EV, Best BM. PMID: 30788337; PMCID: PMC6372542.
      View in: PubMed   Mentions: 1  
    45. Efavirenz pharmacokinetics during pregnancy and infant washout. Antivir Ther. 2019; 24(2):95-103. Kreitchmann R, Schalkwijk S, Best B, Wang J, Colbers A, Stek A, Shapiro D, Cressey T, Mirochnick M, Burger D. PMID: 30530925; PMCID: PMC6642905.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    46. Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease. Clin Pharmacokinet. 2018 12; 57(12):1593-1601. Vande Casteele N, Oyamada J, Shimizu C, Best BM, Capparelli EV, Tremoulet AH, Burns JC. PMID: 29623653.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Elvitegravir/cobicistat pharmacokinetics in pregnant and postpartum women with HIV. AIDS. 2018 11 13; 32(17):2507-2516. Momper JD, Best BM, Wang J, Capparelli EV, Stek A, Barr E, Badell ML, Acosta EP, Purswani M, Smith E, Chakhtoura N, Park K, Burchett S, Shapiro DE, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 30134297; PMCID: PMC6209536.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    48. A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women. Clin Pharmacokinet. 2018 11; 57(11):1421-1433. Schalkwijk S, Ter Heine R, Colbers AC, Huitema ADR, Denti P, Dooley KE, Capparelli E, Best BM, Cressey TR, Greupink R, Russel FGM, Mirochnick M, Burger DM. PMID: 29520730; PMCID: PMC6182466.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum. J Clin Pharmacol. 2019 03; 59(3):386-393. Eke AC, McCormack SA, Best BM, Stek AM, Wang J, Kreitchmann R, Shapiro D, Smith E, Mofenson LM, Capparelli EV, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 30358179; PMCID: PMC6368469.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    50. Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood. J Clin Pharmacol. 2018 12; 58(12):1604-1617. Yang J, Nikanjam M, Best BM, Pinto J, Chadwick EG, Daar ES, Havens PL, Rakhmanina N, Capparelli EV. PMID: 30252146; PMCID: PMC6604805.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Marijuana Use by Breastfeeding Mothers and Cannabinoid Concentrations in Breast Milk. Pediatrics. 2018 09; 142(3). Bertrand KA, Hanan NJ, Honerkamp-Smith G, Best BM, Chambers CD. PMID: 30150212; PMCID: PMC6317767.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansPHPublic Health
    52. Rilpivirine Plasma and Cervicovaginal Concentrations in Women During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2018 07 01; 78(3):308-313. Eke AC, Chakhtoura N, Kashuba A, Best BM, Sykes C, Wang J, Stek AM, Smith E, Calabrese S, Capparelli EV, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 29528944; PMCID: PMC6002878.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    53. Randomized Controlled Trial of Daily Text Messages to Support Adherence to Preexposure Prophylaxis in Individuals at Risk for Human Immunodeficiency Virus: The TAPIR Study. Clin Infect Dis. 2018 05 02; 66(10):1566-1572. Moore DJ, Jain S, Dubé MP, Daar ES, Sun X, Young J, Corado K, Ellorin E, Milam J, Collins D, Blumenthal J, Best BM, Anderson P, Haubrich R, Morris SR. PMID: 29228144; PMCID: PMC6248545.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansPHPublic Health
    54. Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV. AIDS. 2018 03 27; 32(6):729-737. Mulligan N, Best BM, Wang J, Capparelli EV, Stek A, Barr E, Buschur SL, Acosta EP, Smith E, Chakhtoura N, Burchett S, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 29369162; PMCID: PMC5854536.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCellsCTClinical Trials
    55. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. Food Funct. 2018 Jan 24; 9(1):307-319. Moreno-Ulloa A, Nájera-García N, Hernández M, Ramírez-Sánchez I, Taub PR, Su Y, Beltrán-Partida E, Ceballos G, Dugar S, Schreiner G, Best BM, Ciaraldi TP, Henry RR, Villarreal F. PMID: 29171848; PMCID: PMC5783763.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    56. Effect of a Dedicated Pharmacy Student Summer Research Program on Publication Rate. Am J Pharm Educ. 2017 Apr; 81(3):48. Brandl K, Adler D, Kelly C, Taylor P, Best BM. PMID: 28496268; PMCID: PMC5423064.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    57. An Interactive, Multifaceted Approach to Enhancing Pharmacy Students' Health Literacy Knowledge and Confidence. Am J Pharm Educ. 2017 Mar 25; 81(2):32. Mnatzaganian C, Fricovsky E, Best BM, Singh RF. PMID: 28381892; PMCID: PMC5374921.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    58. Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-infected Children, Adolescents and Young Adults With Hyperlipidemia. Pediatr Infect Dis J. 2017 01; 36(1):53-60. Melvin AJ, Montepiedra G, Aaron L, Meyer WA, Spiegel HM, Borkowsky W, Abzug MJ, Best BM, Crain MJ, Borum PR, Graham B, Anthony P, Shin K, Siberry GK, P1063 Study Team. PMID: 27749649; PMCID: PMC5154931.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    59. Etravirine Pharmacokinetics in HIV-Infected Pregnant Women. Front Pharmacol. 2016; 7:239. Mulligan N, Schalkwijk S, Best BM, Colbers A, Wang J, Capparelli EV, Moltó J, Stek AM, Taylor G, Smith E, Hidalgo Tenorio C, Chakhtoura N, van Kasteren M, Fletcher CV, Mirochnick M, Burger D. PMID: 27540363; PMCID: PMC4972814.
      View in: PubMed   Mentions: 8  
    60. Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women. J Acquir Immune Defic Syndr. 2016 07 01; 72(3):289-96. Tran AH, Best BM, Stek A, Wang J, Capparelli EV, Burchett SK, Kreitchmann R, Rungruengthanakit K, George K, Cressey TR, Chakhtoura N, Smith E, Shapiro DE, Mirochnick M, IMPAACT P1026s Protocol Team. PMID: 26918544; PMCID: PMC4911231.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    61. Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (the ANAKID trial). Contemp Clin Trials. 2016 05; 48:70-5. Tremoulet AH, Jain S, Kim S, Newburger J, Arditi M, Franco A, Best B, Burns JC. PMID: 27080929; PMCID: PMC5221485.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    62. Pharmacokinetics of Once Versus Twice Daily Darunavir in Pregnant HIV-Infected Women. J Acquir Immune Defic Syndr. 2015 Sep 01; 70(1):33-41. Stek A, Best BM, Wang J, Capparelli EV, Burchett SK, Kreitchmann R, Rungruengthanakit K, Cressey TR, Mofenson LM, Smith E, Shapiro D, Mirochnick M. PMID: 25950206; PMCID: PMC4579345.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    63. Maraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women. Clin Infect Dis. 2015 Nov 15; 61(10):1582-9. Colbers A, Best B, Schalkwijk S, Wang J, Stek A, Hidalgo Tenorio C, Hawkins D, Taylor G, Kreitchmann R, Burchett S, Haberl A, Kabeya K, van Kasteren M, Smith E, Capparelli E, Burger D, Mirochnick M, PANNA Network and the IMPAACT 1026 Study Team. PMID: 26202768; PMCID: PMC4614410.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    64. Pharmacokinetics of tenofovir during pregnancy and postpartum. HIV Med. 2015 Sep; 16(8):502-11. Best BM, Burchett S, Li H, Stek A, Hu C, Wang J, Hawkins E, Byroads M, Watts DH, Smith E, Fletcher CV, Capparelli EV, Mirochnick M, International Maternal Pediatric and Adolescent AIDS Clinical Trials (IMPAACT) P1026s Team. PMID: 25959631; PMCID: PMC4862736.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    65. Raltegravir pharmacokinetics during pregnancy. J Acquir Immune Defic Syndr. 2014 Dec 01; 67(4):375-81. Watts DH, Stek A, Best BM, Wang J, Capparelli EV, Cressey TR, Aweeka F, Lizak P, Kreitchmann R, Burchett SK, Shapiro DE, Hawkins E, Smith E, Mirochnick M, IMPAACT 1026s study team. PMID: 25162818; PMCID: PMC4213295.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    66. Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics. HIV Med. 2015 Mar; 16(3):176-83. Aweeka FT, Hu C, Huang L, Best BM, Stek A, Lizak P, Burchett SK, Read JS, Watts H, Mirochnick M, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Tea. PMID: 25407158; PMCID: PMC4320673.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    67. Protecting the fetus against HIV infection: a systematic review of placental transfer of antiretrovirals. Clin Pharmacokinet. 2014 Nov; 53(11):989-1004. McCormack SA, Best BM. PMID: 25223699; PMCID: PMC4214885.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsPHPublic Health
    68. Response to urine drug testing for oxycodone and its metabolites as a tool for drug-drug interactions. J Anal Toxicol. 2015 Jan-Feb; 39(1):80. Elder NM, Atayee RS, Best BM, Ma JD. PMID: 25288719.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy. J Antimicrob Chemother. 2015 Jan; 70(1):217-24. Cressey TR, Urien S, Capparelli EV, Best BM, Buranabanjasatean S, Limtrakul A, Rawangban B, Sabsanong P, Treluyer JM, Jourdain G, Stek A, Lallemant M, Mirochnick M. PMID: 25261418; PMCID: PMC4267507.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    70. Authors' reply. J Anal Toxicol. 2014 Sep; 38(7):463. Elder NM, Atayee RS, Best BM, Ma JD. PMID: 24986838.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    71. Evaluation of concomitant methylphenidate and opioid use in patients with pain. J Anal Toxicol. 2014 Sep; 38(7):421-6. Jiang JY, Best BM, Morello CM, Atayee RS, Ma JD. PMID: 24907143.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. Urinary hydrocodone and metabolite distributions in pain patients. J Anal Toxicol. 2014 Sep; 38(7):404-9. Barakat NH, Atayee RS, Best BM, Ma JD. PMID: 24836897.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    73. Urine specimen detection of zolpidem use in patients with pain. J Anal Toxicol. 2014 Jul-Aug; 38(6):322-6. Mann LM, Atayee RS, Best BM, Morello CM, Ma JD. PMID: 24802157.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    74. Observations on hydrocodone and its metabolites in oral fluid specimens of the pain population: comparison with urine. J Opioid Manag. 2014 May-Jun; 10(3):177-86. Cao JM, Ma JD, Morello CM, Atayee RS, Best BM. PMID: 24944068.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    75. Variability in metabolism of imipramine and desipramine using urinary excretion data. J Anal Toxicol. 2014 Jul-Aug; 38(6):368-74. Ramey K, Ma JD, Best BM, Atayee RS, Morello CM. PMID: 24782142.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    76. Naltrexone metabolism and concomitant drug concentrations in chronic pain patients. J Anal Toxicol. 2014 May; 38(4):212-7. Liu JC, Ma JD, Morello CM, Atayee RS, Best BM. PMID: 24659754.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    77. Observation of improved adherence with frequent urine drug testing in patients with pain. J Opioid Manag. 2014 Mar-Apr; 10(2):111-8. Yee DA, Hughes MM, Guo AY, Barakat NH, Tse SA, Ma JD, Best BM, Atayee RS. PMID: 24715666.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    78. Observations of urinary oxycodone and metabolite distributions in pain patients. J Anal Toxicol. 2014 Apr; 38(3):129-34. Elder NM, Atayee RS, Best BM, Ma JD. PMID: 24523296.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    79. Obstetric Pharmacokinetic Dosing Studies are Urgently Needed. Front Pediatr. 2014; 2:9. McCormack SA, Best BM. PMID: 24575394; PMCID: PMC3920104.
      View in: PubMed   Mentions: 24  
    80. Urinary diazepam metabolite distribution in a chronic pain population. J Anal Toxicol. 2014 Apr; 38(3):135-42. Luk S, Atayee RS, Ma JD, Best BM. PMID: 24500275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    81. Factors affecting carisoprodol metabolism in pain patients using urinary excretion data. J Anal Toxicol. 2014 Apr; 38(3):122-8. Tse SA, Atayee RS, Ma JD, Best BM. PMID: 24488112.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    82. Observations on the urine metabolic profile of codeine in pain patients. J Anal Toxicol. 2014 Mar; 38(2):86-91. Yee DA, Atayee RS, Best BM, Ma JD. PMID: 24396053.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    83. Monitoring oxycodone use in patients with chronic pain: analysis of oxycodone and metabolite excretion in saliva and urine. J Opioid Manag. 2014 Jan-Feb; 10(1):47-56. Moy KV, Ma JD, Morello CM, Atayee RS, Best BM. PMID: 24604569.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    84. Randomized trial of central nervous system-targeted antiretrovirals for HIV-associated neurocognitive disorder. Clin Infect Dis. 2014 Apr; 58(7):1015-22. Ellis RJ, Letendre S, Vaida F, Haubrich R, Heaton RK, Sacktor N, Clifford DB, Best BM, May S, Umlauf A, Cherner M, Sanders C, Ballard C, Simpson DM, Jay C, McCutchan JA. PMID: 24352352; PMCID: PMC3952601.
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    85. Impact of a first-year student pharmacist diabetes self-care education program. Am J Pharm Educ. 2013 Dec 16; 77(10):215. Morello CM, Neighbors M, Luu L, Kobayashi S, Mutrux B, Best BM. PMID: 24371339; PMCID: PMC3872934.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    86. Tricyclic antidepressants: is your patient taking them? Observations on adherence and unreported use using prescriber-reported medication lists and urine drug testing. Pain Med. 2014 Mar; 15(3):355-63. Bordson SJ, Atayee RS, Ma JD, Best BM. PMID: 24308804.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    87. Factors impacting variability of the urinary normeperidine-to-meperidine metabolic ratio in patients with chronic pain. J Anal Toxicol. 2014 Jan-Feb; 38(1):1-7. Moy KV, Ma JD, Best BM, Atayee RS. PMID: 24133175.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    88. Urine specimen detection of concurrent nonprescribed medicinal and illicit drug use in patients prescribed buprenorphine. J Anal Toxicol. 2013 Nov-Dec; 37(9):636-41. Guo AY, Ma JD, Best BM, Atayee RS. PMID: 24080973.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    89. Reduced indinavir exposure during pregnancy. Br J Clin Pharmacol. 2013 Sep; 76(3):475-83. Cressey TR, Best BM, Achalapong J, Stek A, Wang J, Chotivanich N, Yuthavisuthi P, Suriyachai P, Prommas S, Shapiro DE, Watts DH, Smith E, Capparelli E, Kreitchmann R, Mirochnick M, IMPAACT P1026s team. PMID: 23305215; PMCID: PMC3769674.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    90. Pharmacokinetics of an increased atazanavir dose with and without tenofovir during the third trimester of pregnancy. J Acquir Immune Defic Syndr. 2013 May 01; 63(1):59-66. Kreitchmann R, Best BM, Wang J, Stek A, Caparelli E, Watts DH, Smith E, Shapiro DE, Rossi S, Burchett SK, Hawkins E, Byroads M, Cressey TR, Mirochnick M. PMID: 23392467; PMCID: PMC3625451.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    91. Etravirine in CSF is highly protein bound. J Antimicrob Chemother. 2013 May; 68(5):1161-8. Nguyen A, Rossi S, Croteau D, Best BM, Clifford D, Collier AC, Gelman B, Marra C, McArthur J, McCutchan JA, Morgello S, Simpson D, Ellis RJ, Grant I, Capparelli E, Letendre S, CHARTER Group. PMID: 23335197; PMCID: PMC3625433.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    92. Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration. J Antimicrob Chemother. 2013 Mar; 68(3):684-9. Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S, CHARTER Group. PMID: 23143899; PMCID: PMC3566670.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    93. Incidence of Kawasaki disease in northern European countries. Pediatr Int. 2012 Dec; 54(6):770-2. Salo E, Griffiths EP, Farstad T, Schiller B, Nakamura Y, Yashiro M, Uehara R, Best BM, Burns JC. PMID: 22726311; PMCID: PMC3467350.
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    94. An active-learning assignment involving peer-to-peer presentations to improve pharmacy students' attitudes and knowledge of dietary supplements. Am J Pharm Educ. 2012 Aug 10; 76(6):113. Atayee RS, Singh RF, Best BM, Freedman BA, Morello CM. PMID: 22919089; PMCID: PMC3425928.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    95. Pharmacokinetic analysis of ziconotide (SNX-111), an intrathecal N-type calcium channel blocking analgesic, delivered by bolus and infusion in the dog. Neuromodulation. 2012 Nov-Dec; 15(6):508-19; discussion 519. Yaksh TL, de Kater A, Dean R, Best BM, Miljanich GP. PMID: 22748108; PMCID: PMC3514653.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    96. Relationship between the concentration of hydrocodone and its conversion to hydromorphone in chronic pain patients using urinary excretion data. J Anal Toxicol. 2012 May; 36(4):257-64. Barakat NH, Atayee RS, Best BM, Pesce AJ. PMID: 22511700.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    97. Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients. J Anal Toxicol. 2012 May; 36(4):239-49. Leimanis E, Best BM, Atayee RS, Pesce AJ. PMID: 22511698.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    98. Observations on the metabolism of morphine to hydromorphone in pain patients. J Anal Toxicol. 2012 May; 36(4):250-6. Hughes MM, Atayee RS, Best BM, Pesce AJ. PMID: 22511699.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    99. Evaluating the relationship between carisoprodol concentrations and meprobamate formation and inter-subject and intra-subject variability in urinary excretion data of pain patients. J Anal Toxicol. 2012 May; 36(4):221-31. Tse SA, Atayee RS, Best BM, Pesce AJ. PMID: 22511696.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    100. Observations on the urine metabolic ratio of oxymorphone to oxycodone in pain patients. J Anal Toxicol. 2012 May; 36(4):232-8. Yee DA, Best BM, Atayee RS, Pesce AJ. PMID: 22511697.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    101. Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration. AIDS. 2012 Apr 24; 26(7):890-3. Croteau D, Best BM, Letendre S, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S, Grant I, CHARTER Group. PMID: 22313954; PMCID: PMC3454507.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    102. Low cerebrospinal fluid concentrations of the nucleotide HIV reverse transcriptase inhibitor, tenofovir. J Acquir Immune Defic Syndr. 2012 Apr 01; 59(4):376-81. Best BM, Letendre SL, Koopmans P, Rossi SS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Capparelli EV, Ellis RJ, Grant I, CHARTER Study Group. PMID: 22217676; PMCID: PMC3299895.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    103. Efavirenz pharmacokinetics during the third trimester of pregnancy and postpartum. J Acquir Immune Defic Syndr. 2012 Mar 01; 59(3):245-52. Cressey TR, Stek A, Capparelli E, Bowonwatanuwong C, Prommas S, Sirivatanapa P, Yuthavisuthi P, Neungton C, Huo Y, Smith E, Best BM, Mirochnick M, IMPAACT P1026s Team. PMID: 22083071; PMCID: PMC3288559.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCellsCTClinical Trials
    104. Therapeutic amprenavir concentrations in cerebrospinal fluid. Antimicrob Agents Chemother. 2012 Apr; 56(4):1985-9. Croteau D, Letendre S, Best BM, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Way L, Capparelli E, Grant I, CHARTER Group. PMID: 22290964; PMCID: PMC3318381.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    105. Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children. J Acquir Immune Defic Syndr. 2011 Dec 01; 58(4):385-91. Best BM, Capparelli EV, Diep H, Rossi SS, Farrell MJ, Williams E, Lee G, van den Anker JN, Rakhmanina N. PMID: 21876444; PMCID: PMC3205189.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    106. Effect of pregnancy on emtricitabine pharmacokinetics. HIV Med. 2012 Apr; 13(4):226-35. Stek AM, Best BM, Luo W, Capparelli E, Burchett S, Hu C, Li H, Read JS, Jennings A, Barr E, Smith E, Rossi SS, Mirochnick M. PMID: 22129166; PMCID: PMC3342997.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    107. Increased incidence and severity of Kawasaki disease among Filipino-Americans in San Diego county. Pediatr Infect Dis J. 2011 Oct; 30(10):909-11. Tremoulet AH, Devera G, Best BM, Jimenez-Fernandez S, Sun X, Jain S, Burns JC. PMID: 21552184.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    108. Cardiovascular biomarkers in acute Kawasaki disease. Int J Cardiol. 2013 Mar 20; 164(1):58-63. Sato YZ, Molkara DP, Daniels LB, Tremoulet AH, Shimizu C, Kanegaye JT, Best BM, Snider JV, Frazer JR, Maisel A, Burns JC. PMID: 21777987; PMCID: PMC3253177.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    109. Atazanavir pharmacokinetics with and without tenofovir during pregnancy. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):412-9. Mirochnick M, Best BM, Stek AM, Capparelli EV, Hu C, Burchett SK, Rossi SS, Hawkins E, Basar M, Smith E, Read JS, IMPAACT 1026s Study Team. PMID: 21283017; PMCID: PMC3125419.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    110. Antiretroviral therapy adherence, medication use, and health care costs during 3 years of a community pharmacy medication therapy management program for Medi-Cal beneficiaries with HIV/AIDS. J Manag Care Pharm. 2011 Apr; 17(3):213-23. Hirsch JD, Gonzales M, Rosenquist A, Miller TA, Gilmer TP, Best BM. PMID: 21434698; PMCID: PMC10437600.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    111. Antiretroviral pharmacology: special issues regarding pregnant women and neonates. Clin Perinatol. 2010 Dec; 37(4):907-27, xi. Mirochnick M, Best BM, Clarke DF. PMID: 21078458.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    112. Medication therapy management services in community pharmacy: a pilot programme in HIV specialty pharmacies. J Eval Clin Pract. 2010 Dec; 16(6):1142-6. Rosenquist A, Best BM, Miller TA, Gilmer TP, Hirsch JD. PMID: 21143346.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    113. Efavirenz concentrations in CSF exceed IC50 for wild-type HIV. J Antimicrob Chemother. 2011 Feb; 66(2):354-7. Best BM, Koopmans PP, Letendre SL, Capparelli EV, Rossi SS, Clifford DB, Collier AC, Gelman BB, Mbeo G, McCutchan JA, Simpson DM, Haubrich R, Ellis R, Grant I, CHARTER Group. PMID: 21098541; PMCID: PMC3019085.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    114. Total raltegravir concentrations in cerebrospinal fluid exceed the 50-percent inhibitory concentration for wild-type HIV-1. Antimicrob Agents Chemother. 2010 Dec; 54(12):5156-60. Croteau D, Letendre S, Best BM, Ellis RJ, Breidinger S, Clifford D, Collier A, Gelman B, Marra C, Mbeo G, McCutchan A, Morgello S, Simpson D, Way L, Vaida F, Ueland S, Capparelli E, Grant I, CHARTER Group. PMID: 20876368; PMCID: PMC2981289.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    115. Lopinavir tablet pharmacokinetics with an increased dose during pregnancy. J Acquir Immune Defic Syndr. 2010 Aug; 54(4):381-8. Best BM, Stek AM, Mirochnick M, Hu C, Li H, Burchett SK, Rossi SS, Smith E, Read JS, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group 1026s Study Team. PMID: 20632458; PMCID: PMC3265163.
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    116. Transcript abundance patterns in Kawasaki disease patients with intravenous immunoglobulin resistance. Hum Immunol. 2010 Sep; 71(9):865-73. Fury W, Tremoulet AH, Watson VE, Best BM, Shimizu C, Hamilton J, Kanegaye JT, Wei Y, Kao C, Mellis S, Lin C, Burns JC. PMID: 20600450; PMCID: PMC2929310.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    117. Enhancing an introductory Pharmacy Practice Experience at free medical clinics. Int J Pharm Pract. 2010 Feb; 18(1):51-7. Morello CM, Singh RF, Chen KJ, Best BM. PMID: 20405596.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    118. Variability of transdermal fentanyl metabolism and excretion in pain patients. J Opioid Manag. 2010 Jan-Feb; 6(1):29-39. Cole JM, Best BM, Pesce AJ. PMID: 20297612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    119. Lopinavir protein binding in HIV-1-infected pregnant women. HIV Med. 2010 Apr; 11(4):232-8. Aweeka FT, Stek A, Best BM, Hu C, Holland D, Hermes A, Burchett SK, Read J, Mirochnick M, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Tea. PMID: 20002783; PMCID: PMC2874627.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    120. Should antiretroviral therapy for HIV infection be tailored for intracerebral penetration? Neth J Med. 2009 Jun; 67(6):206-11. Koopmans PP, Ellis R, Best BM, Letendre S. PMID: 19749389; PMCID: PMC5077299.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    121. Periungual desquamation in patients with Kawasaki disease. Pediatr Infect Dis J. 2009 Jun; 28(6):538-9. Wang S, Best BM, Burns JC. PMID: 19483521; PMCID: PMC2738931.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    122. Recognition of a Kawasaki disease shock syndrome. Pediatrics. 2009 May; 123(5):e783-9. Kanegaye JT, Wilder MS, Molkara D, Frazer JR, Pancheri J, Tremoulet AH, Watson VE, Best BM, Burns JC. PMID: 19403470; PMCID: PMC2848476.
      View in: PubMed   Mentions: 159     Fields:    Translation:Humans
    123. Pyuria associated with acute Kawasaki disease and fever from other causes. Pediatr Infect Dis J. 2009 May; 28(5):440-3. Shike H, Kanegaye JT, Best BM, Pancheri J, Burns JC. PMID: 19319019; PMCID: PMC2738928.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    124. Low atazanavir concentrations in cerebrospinal fluid. AIDS. 2009 Jan 02; 23(1):83-7. Best BM, Letendre SL, Brigid E, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Ellis R, Capparelli EV, Grant I, CHARTER Group. PMID: 19050389; PMCID: PMC2642983.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCTClinical Trials
    125. Evaluation of the first year of a pilot program in community pharmacy: HIV/AIDS medication therapy management for Medi-Cal beneficiaries. J Manag Care Pharm. 2009 Jan-Feb; 15(1):32-41. Hirsch JD, Rosenquist A, Best BM, Miller TA, Gilmer TP. PMID: 19125548; PMCID: PMC10438302.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    126. Lopinavir exposure with an increased dose during pregnancy. J Acquir Immune Defic Syndr. 2008 Dec 15; 49(5):485-91. Mirochnick M, Best BM, Stek AM, Capparelli E, Hu C, Burchett SK, Holland DT, Smith E, Gaddipati S, Read JS, PACTG 1026s Study Team. PMID: 18989231; PMCID: PMC3912695.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    127. Development of an ambulatory palliative care pharmacist practice. J Palliat Med. 2008 Oct; 11(8):1077-82. Atayee RS, Best BM, Daniels CE. PMID: 18980446.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    128. Pharmacokinetics of new 625 mg nelfinavir formulation during pregnancy and postpartum. HIV Med. 2008 Nov; 9(10):875-82. Read JS, Best BM, Stek AM, Hu C, Capparelli EV, Holland DT, Burchett SK, Smith ME, Sheeran EC, Shearer WT, Febo I, Mirochnick M. PMID: 18795962; PMCID: PMC2732353.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    129. Infliximab treatment of intravenous immunoglobulin-resistant Kawasaki disease. J Pediatr. 2008 Dec; 153(6):833-8. Burns JC, Best BM, Mejias A, Mahony L, Fixler DE, Jafri HS, Melish ME, Jackson MA, Asmar BI, Lang DJ, Connor JD, Capparelli EV, Keen ML, Mamun K, Keenan GF, Ramilo O. PMID: 18672254; PMCID: PMC2856847.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    130. Efavirenz--still first-line king? Expert Opin Drug Metab Toxicol. 2008 Jul; 4(7):965-72. Best BM, Goicoechea M. PMID: 18624683; PMCID: PMC5761737.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    131. Implications of gender and pregnancy for antiretroviral drug dosing. Curr Opin HIV AIDS. 2008 May; 3(3):277-82. Best BM, Capparelli EV. PMID: 19372979; PMCID: PMC2804899.
      View in: PubMed   Mentions: 3     Fields:    
    132. Chronic administration of nevirapine during pregnancy: impact of pregnancy on pharmacokinetics. HIV Med. 2008 Apr; 9(4):214-20. Capparelli EV, Aweeka F, Hitti J, Stek A, Hu C, Burchett SK, Best B, Smith E, Read JS, Watts H, Nachman S, Thorpe EM, Spector SA, Jimenez E, Shearer WT, Foca M, Mirochnick M, PACTG 1026S Study Team, PACTG P1022 Study Team. PMID: 18366444; PMCID: PMC2755564.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    133. Resistance to intravenous immunoglobulin in children with Kawasaki disease. J Pediatr. 2008 Jul; 153(1):117-21. Tremoulet AH, Best BM, Song S, Wang S, Corinaldesi E, Eichenfield JR, Martin DD, Newburger JW, Burns JC. PMID: 18571548; PMCID: PMC2526555.
      View in: PubMed   Mentions: 154     Fields:    Translation:Humans
    134. Greater tenofovir-associated renal function decline with protease inhibitor-based versus nonnucleoside reverse-transcriptase inhibitor-based therapy. J Infect Dis. 2008 Jan 01; 197(1):102-8. Goicoechea M, Liu S, Best B, Sun S, Jain S, Kemper C, Witt M, Diamond C, Haubrich R, Louie S, California Collaborative Treatment Group 578 Team. PMID: 18171292.
      View in: PubMed   Mentions: 111     Fields:    Translation:Humans
    135. Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol. 2008 Jan; 65(1):65-70. Letendre S, Marquie-Beck J, Capparelli E, Best B, Clifford D, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S, Simpson D, Grant I, Ellis RJ, CHARTER Group. PMID: 18195140; PMCID: PMC2763187.
      View in: PubMed   Mentions: 384     Fields:    Translation:Humans
    136. A randomized controlled trial of therapeutic drug monitoring in treatment-naive and -experienced HIV-1-infected patients. J Acquir Immune Defic Syndr. 2007 Dec 01; 46(4):433-42. Best BM, Goicoechea M, Witt MD, Miller L, Daar ES, Diamond C, Tilles JG, Kemper CA, Larsen R, Holland DT, Sun S, Jain S, Wagner G, Capparelli EV, McCutchan JA, Haubrich RH, California Collaborative Treatment Group 578 Study Team. PMID: 17786128.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    137. Efavirenz/emtricitabine/tenofovir disoproxil fumarate fixed-dose combination: first-line therapy for all? Expert Opin Pharmacother. 2007 Feb; 8(3):371-82. Goicoechea M, Best B. PMID: 17266471.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    138. The role of cohort studies in drug development: clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the central nervous system. J Neuroimmune Pharmacol. 2007 Mar; 2(1):120-7. Letendre SL, Marquie-Beck J, Ellis RJ, Woods SP, Best B, Clifford DB, Collier AC, Gelman BB, Marra C, McArthur JC, McCutchan JA, Morgello S, Simpson D, Alexander TJ, Durelle J, Heaton R, Grant I, CHARTER Group. PMID: 18040835.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    139. Therapeutic ritonavir-boosted atazanavir plasma concentration and concurrent omeprazole use. AIDS. 2006 Oct 24; 20(16):2127-8. Goicoechea M, Best B, Capparelli E, Caperna J, Ballard C, Haubrich R. PMID: 17053363.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    140. Reduced lopinavir exposure during pregnancy. AIDS. 2006 Oct 03; 20(15):1931-9. Stek AM, Mirochnick M, Capparelli E, Best BM, Hu C, Burchett SK, Elgie C, Holland DT, Smith E, Tuomala R, Cotter A, Read JS. PMID: 16988514.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCellsCTClinical Trials
    141. Concurrent use of efavirenz and oxcarbazepine may not affect efavirenz plasma concentrations. Clin Infect Dis. 2006 Jul 01; 43(1):116-7. Goicoechea M, Best B, Capparelli E, Haubrich R, California Collaborative Treatment Group. PMID: 16758435.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    142. Failure of modified directly observed therapy combined with therapeutic drug monitoring to enhance antiretroviral adherence in a patient with major depression. AIDS Patient Care STDS. 2006 Apr; 20(4):233-7. Goicoechea M, Best B, Seefried E, Wagner G, Capparelli E, Haubrich R, California Collaborative Treatment Group (CCTG). PMID: 16623621.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    143. Impact of pregnancy on abacavir pharmacokinetics. AIDS. 2006 Feb 28; 20(4):553-60. Best BM, Mirochnick M, Capparelli EV, Stek A, Burchett SK, Holland DT, Read JS, Smith E, Hu C, Spector SA, Connor JD, PACTG P1026s Study Team. PMID: 16470119.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    144. Tipranavir: a protease inhibitor for multi-drug resistant HIV-1. Expert Opin Investig Drugs. 2006 Jan; 15(1):59-70. Best B, Haubrich R. PMID: 16370934.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    145. Pharmacokinetic and tolerability assessment of a pediatric oral formulation of pentoxifylline in kawasaki disease. Curr Ther Res Clin Exp. 2003 Feb; 64(2):96-115. Best BM, Burns JC, DeVincenzo J, Phelps SJ, Blumer JL, Wilson JT, Capparelli EV, Connor JD, Pediatric Pharmacology Research Unit Network. PMID: 24944359; PMCID: PMC4053025.
      View in: PubMed   Mentions: 3     Fields:    
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